ARITA Michitsune 有田通恒

… Alternative Names

有田通恒アリタミチツネ

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Researcher Number	80307719
Other IDs
Affiliation (Current)	2025: 東邦大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2025: 東邦大学, 医学部, 助教 2009 – 2023: 東邦大学, 医学部, 助教 2000 – 2005: 東邦大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related / Digestive surgery Except Principal Investigator Digestive surgery / Digestive surgery / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 低酸素 / p53 / EMAST / 大腸癌 / DNAミスマッチ修復遺伝子 / 悪性化機構 / マイクロサテライト不安定 / 進行大腸癌 / DNAミスマッチ修復 / MSH3 … More / 癌 / ゲノム不安定性 / 転移 / 癌微小環境 / 転写因子 / 転写調節機構 / hMLH1遺伝子 / CRISPR-Cas9 / p53変異 / マイクロサテライト / ミスマッチ修復 / p53変異分類 / TrkB / がん微小環境 / 散発性大腸癌 / 進行性大腸癌 / 転写制御因子 / hnRPH1 / SYF2 / 低酸素状態 / CXXC5 / MLH1 / 転写制御 / 腫瘍微小環境 / 小腸大腸肛門外科学 / ch6Orf145 / c6orf145 / TIF1α / タンパク結合部位 / 酵母one-hybrid法 / p29 / 転写制御機構 / 転写調節因子 / hMLH1 / trans-acting factor / cis-element / プロモーター領域 / 細胞株 … More Except Principal Investigator EMAST / DNAミスマッチ修復遺伝子 / 大腸癌 / DNAミスマッチ修復 / ゲノム不安定性 / LOH / histone / cell lines / hMSH2 gene / hMLH1 gene / DNA mismatch repair genes / colorectal cancer / ミスマッチ修復遺伝子 / 細胞株 / hMSH2遺伝子 / hMLH1遺伝子 / p53 / 低酸素 / 大腸がん / MSH3 / マイクロサテライト不安定性 / 卵巣癌 / DNA double-strand breaks / drug sensitivity / microsatellite instability / molecular genetic marker / DNA mismatch repair / colorectal carcinoma / 散発性大腸癌 / 抗癌薬感受性 / マクロサテライト不安定性 / 遺伝性非ポーリープ性大腸癌 / DSB / 薬剤感受性 / MSI / 分子遺伝学的マーカー / transcription factor / acetylation / アセチル化状態 / 転写活性 / ヒストンH4 / 転写因子 / アセチル化 / chemotherapeutic agents / drug-resistance / 化学療法剤 / 薬剤耐性 / DNAミスマッチ遺伝子 / GLUT1 / DNA修復 / 発現制御 / 遺伝子 Less

p53に依存した低酸素性DNAミスマッチ修復の根本的理解と進行大腸癌攻略への挑戦Principal Investigator
- Principal Investigator
  
  有田通恒
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Toho University
Investigation of mechanism by which advanced colorectal cancer progresses EMAST-relating malignancy in hypoxiaPrincipal Investigator
- Principal Investigator
  
  有田通恒
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Toho University
予後改善を目的としたEMAST卵巣癌の発生機構の解明
- Principal Investigator
  
  渡部洋
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Identification of responsible genes for advanced colorectal cancer: Development of in vitro system that mimics EMAST-related tumor-progression regulated by p53.Principal Investigator
- Principal Investigator
  
  Arita Michitsune
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Toho University
Identification of key factors to drive metastasis of progressive colorectal cancers: A search focusing transient players at early stage of metastasisPrincipal Investigator
- Principal Investigator
  
  ARITA Michitsune
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Toho University
Investigation of an EMAST-generating tumor microenvironment and its relating malignant progression for colorectal cancerPrincipal Investigator
- Principal Investigator
  
  ARITA Michitsune
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Toho University
Studies in molecular events of EMAST colorectal cancer and prognostic factors
- Principal Investigator
  
  HEMMI Hiromichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Toho University
Molecular mechanism of transcriptional regulation forDNA repair genes: Identification of partner proteins for CXXC5, a novel MLH1 transcriptional factorPrincipal Investigator
- Principal Investigator
  
  ARITA Michitsune
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Toho University
Molecular mechanism of hypoxia-induced genome instability in human colorectal cancer
- Principal Investigator
  
  HEMMI Hiromichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Toho University
Development of easy procedure for determining MSI tumor and its application on diagnosis in colorectal cancer
- Principal Investigator
  
  HEMMI Hiromichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Toho University
ミスマッチ修復遺伝子hMLH1の転写制御機構の解明:転写因子の同定とその異常検索Principal Investigator
- Principal Investigator
  
  有田通恒
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Toho University
ミスマッチ修復遺伝子の転写制御機構の検討:転写因子の単離同定と役割の解明Principal Investigator
- Principal Investigator
  
  有田通恒
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Toho University
Study for inactivation mechanism of tumor-associated genes in sporadic colorectal cancers
- Principal Investigator
  
  HEMMI Hiromichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  TOHO UNIVERSITY
Basic study for establishment of chemotherapy of DNA mismatch repair-deficient colorectal cancers : Specificity of DNA damage and drug sensitivity
- Principal Investigator
  
  FUNAHASHI Kimihiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  TOHO UNIVERSITY

All 2021 2020 2017 2015 2014 2012 2011 2010 2009 Other

All Journal Article Presentation Patent

[Journal Article] Licochalcone A Inhibits BDNF and TrkB Gene Expression and Hypoxic Growth of Human Tumor Cell Lines2020
- Author(s)
  Arita Michitsune、Koike Junichi、Yoshikawa Nobuji、Kondo Motonari、Hemmi Hiromichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 2 Pages: 506-518
- DOI
  10.3390/ijms21020506
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09229, KAKENHI-PROJECT-16K10555
[Journal Article] 分子標的薬の基礎：DNAミスマッチ修復2020
- Author(s)
  有田通恒、渡部洋
- Journal Title
  
  産科と婦人科
  
  Volume: 87 Pages: 17-21
- Data Source
  KAKENHI-PROJECT-19K09229
[Journal Article] Down-regulation of MutS homolog 3 by hypoxia in human colorectal cancer2012
- Author(s)
  Li J, Koike J, Kugoh H, Arita M, Ohhira T, Kikuchi Y, Funahashi K, Takamatsu K, Boland CR, Koi M, Hemmi H
- Journal Title
  
  Biochim Biophys Acta -Molecular Cell Research
  
  Volume: 1823(4) Issue: 4 Pages: 889-899
- DOI
  10.1016/j.bbamcr.2012.01.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200038, KAKENHI-PROJECT-21591736, KAKENHI-PROJECT-22501012, KAKENHI-PROJECT-22591495
[Journal Article] Downregulation of MutS homolog 3 by hypoxia in human colorectal cancer2012
- Author(s)
  Li J, Koike J, Kugoh H, Arita M, Ohhira T, Kikuchi Y. Funahashi K, Takamatsu K, Boland CR, Koi M, Hemmi H
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1823(4) Pages: 889-99
- URL
  http://dx.doi.org/10.1016/j.bbamcr.2012.01.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591736
[Journal Article] Factors regulating angiotensin-converting enzyme 2 expression in a human proximal tubular cell line HK-2.2011
- Author(s)
  Aoki T, Hemmi H, Arita M, et al
- Journal Title
  
  J Med Soc Toho
  
  Volume: 58(1) Pages: 19-26
- NAID
  40017650365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591736
[Journal Article] Effluent markers related to epithelial mesenchymal transition with adjusted values for effluent cancer antigen 125 in peritoneal dialysis patients2011
- Author(s)
  Mizuiri S, Hemmi H, et al
- Journal Title
  
  Int J Nephrol
  
  Volume: 2011 Pages: 2610401-5
- DOI
  10.4061/2011/261040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591736, KAKENHI-PROJECT-22591495
[Journal Article] Effluent markers related to epithelial mesenchymal transition with adjusted values for effluent cancer antigen 125 in peritoneal dialysis patients.2011
- Author(s)
  Mizuiri S, Hemmi H, Arita M, et al
- Journal Title
  
  Int J Nephrol
  
  Volume: (in Press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591736
[Journal Article] Increased ACE and decreased ACE2 expression in kidneys from patients with IgA nephropathy2011
- Author(s)
  Mizuiri S, Hemmi H, Arita M, Aoki T, Ohashi Y, Miyagi M, Sakai K, Shibuya K, Hase H, and Aikawa A.
- Journal Title
  
  Nephron Clin Prac
  
  Volume: 117(1) Issue: 1 Pages: c57-c66
- DOI
  10.1159/000319648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591495
[Journal Article] Urinary angiotensin-converting enzyme 2 in patients with CKD2011
- Author(s)
  Mizuiri S, Aoki T, Hemmi H, Arita M, Sakai K, and Aikawa A
- Journal Title
  
  Nephrology(Carlton)
  
  Volume: 16(6) Issue: 6 Pages: 567-72
- DOI
  10.1111/j.1440-1797.2011.01467.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591495
[Patent] 制癌剤2014
- Inventor(s)
  逸見仁道, 有田通恒
- Industrial Property Rights Holder
  逸見仁道, 有田通恒
- Industrial Property Rights Type
  特許
- Filing Date
  2014-07-16
- Data Source
  KAKENHI-PROJECT-24591985
[Presentation] 上皮性卵巣癌におけるDNAミスマッチ修復異常の解析2021
- Author(s)
  有田通恒
- Organizer
  第62回　日本婦人科腫瘍学会学術講演
- Invited
- Data Source
  KAKENHI-PROJECT-19K09229
[Presentation] マイクロサテライト不安定性の一形式であるEMASTの発生過程におけるp53の役割2017
- Author(s)
  有田通恒, 小池淳一，近藤元就，逸見仁道
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K10555
[Presentation] 甘草由来化合物Licochalcone AによるTrkB mRNA分解促進作用2017
- Author(s)
  有田通恒, 小池淳一, 吉川展司，近藤元就，逸見仁道
- Organizer
  第59回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10555
[Presentation] 甘草由来成分リコカルコンAの抗がん活性：TrkB-JNK シグナリング阻害を介した神経芽腫細胞増殖抑制2015
- Author(s)
  有田通恒
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25462071
[Presentation] Licochalcone A inhibits hypoxic and normoxic growth via different proliferative pathways in a human neuroblastoma cell line SK-N-SH2015
- Author(s)
  有田通恒
- Organizer
  第57回日本小児血液・がん学会学術集会
- Place of Presentation
  甲府富士屋ホテル（山梨県・甲府市）
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-25462071
[Presentation] EMAST大腸がんの悪性化に寄与する遺伝子の検索．2014
- Author(s)
  有田通恒,　近藤元就，逸見仁道.
- Organizer
  第73回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24591985
[Presentation] N-myc非増幅神経芽腫細胞株SK-N-SHが示す低酸素応答の施設間多様性2014
- Author(s)
  有田通恒,　黒岩　実，上條岳彦，近藤元就，逸見仁道.
- Organizer
  第56回日本小児血液・がん学会学術集会
- Place of Presentation
  岡山コンベンションセンター、岡山シティミュージアム（岡山県・岡山市）
- Year and Date
  2014-11-28
- Data Source
  KAKENHI-PROJECT-24591985
[Presentation] Hypoxic down-regulation of DNA mismatch repair gene hMSH3 and genetic instability of colorectal cancer2012
- Author(s)
  Hemmi H, Arita M, Koike J, Kikuchi Y, Funahashi K, Ohira T, Kugoh H, Kondo M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] DNA ミスマッチ修復遺伝子 MSH3による EMAST 腫瘍発生の分子機構2012
- Author(s)
  有田通恒,児井稔,久郷裕之,近藤元就,逸見仁
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] 低酸素による hMLH1 発現抑制における SYF2 おより hnRPH1 の役割2011
- Author(s)
  有田通恒,李傑,安井明,近藤元就,逸見仁道
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] 低酸素によるhMLH1発現抑制におけるSYF2およびhnRPH1の役割2011
- Author(s)
  有田通恒
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] N-myc非増幅神経芽腫細胞における N-myc の役割2011
- Author(s)
  李傑,有田通恒,柴田祐充子,岩崎維和夫,黒岩実,近藤元就,逸見仁道
- Organizer
  第53回日本小児血液・がん学会学術集会
- Place of Presentation
  前橋
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] 低酸素によるhMLH1発現抑制におけるSYF2およびhnRPH1の役割2011
- Author(s)
  有田通恒, 逸見仁道, 他
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21591736
[Presentation] 低酸素による hMLH1 発現抑制時の転写因子CXXC5, SYF2 およびhnRPH1 の関与2011
- Author(s)
  有田通恒,李傑,菅野新一郎,菊池由宣,安井明,近藤元就,逸見仁道
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] 低酸素によるhMLH1発現抑制時の転写因子CXXC5, SYF2およびhnRPH1の関与2011
- Author(s)
  有田通恒, 李傑, 菅野新一郎, 菊池由宣, 安井明, 近藤元就, 逸見仁道
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21591736
[Presentation] N-myc非増幅神経芽腫細胞におけるN-mycの役割2011
- Author(s)
  李傑, 有田通恒, 柴田祐充子, 岩崎維和夫, 黒岩実, 近藤元就, 逸見仁道
- Organizer
  第53回日本小児血液・がん学会学術集会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-21591736
[Presentation] 低酸素によるhMLH1発現抑制時の転写因子CXXC5,SYF2およびhnRNPH1の関与2011
- Author(s)
  有田通恒
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] 低酸素によるhMLH1発現抑制におけるSYF2およびhnRPH1の役割2011
- Author(s)
  有田通恒, 李傑, 安井明, 近藤元就, 逸見仁道
- Organizer
  The 70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-21591736
[Presentation] Regulation of MMR genes and stem cell markers in hypoxia in colorectal cancer cells.2010
- Author(s)
  Li J, Arita M, Koike J, Hemmi H
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] A novel transcriptional regulator, CXXC5 zinc finger protein, for a DNA mismatch repair gene, hMLH12010
- Author(s)
  有田通恒
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] Regulation of MMR genes and stem cell markers in hypoxia in colorectal cancer cells2010
- Author(s)
  Li J, Arita M, Koike J, Hemmi H
- Organizer
  The 69th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-21591736
[Presentation] CXXC5とSYF2/p29によるhMLH1転写制御2010
- Author(s)
  有田通恒
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] ヒト尿細管上皮細胞におけるブドウ糖,ヒト血清アルブミンによる ACE2 発現の変化2010
- Author(s)
  青木敏行,水入苑生,有田通恒,逸見仁道,大谷隆俊,鈴木康紀,服部吉成,田中仁英,大橋靖,酒井謙,相川厚
- Organizer
  第53回日本腎臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] CXXC5とSYF/p29によるhM転写制御, a zinc finger protein2010
- Author(s)
  有田通恒, 李傑, 菅野新一郎, 安井明, 逸見仁道
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591736
[Presentation] CXXC5 と SYF2/p29 によるhMLH1 転写制御2010
- Author(s)
  有田通恒,李傑,菅野新一郎,安井明,逸見仁道
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] A novel transcriptional regulator, CXXC5 zinc finger protein, for a DNA mismatch repair gene, hMLH12010
- Author(s)
  Arita M, Li J, Yasui A, Hemmi H
- Organizer
  The 69th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-21591736
[Presentation] Regulation of MMR genes and stem cell markers in hypoxia in colorectal cancer cells.(English Workshop)2010
- Author(s)
  Li J, Arita M, Koike J, Hemmi H.
- Organizer
  The 69th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21591736
[Presentation] A novel transcriptional regulator, CXXC5 zinc finger protein, for a DNA mismatch repair gene, hMLH12010
- Author(s)
  Arita M, Li J, Yasui A, Hemmi H
- Organizer
  A novel transcriptional regulator, CXXC5 zinc finger protein, for a DNA mismatch repair gene, hMLH1
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] 腎 ACE2 発現低下は糖尿病腎症に特異的か?2010
- Author(s)
  水入苑生,逸見仁道,有田通恒,酒井謙,大橋靖,田中仁英,服部吉成,鈴木康紀,渋谷和俊,相川厚
- Organizer
  第53回日本腎臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] 大腸がん由来細胞株におけるhMSH3 転写制御機構2010
- Author(s)
  李傑,有田通恒,児井稔,逸見仁道
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] 大腸がん由来細胞株におけるhMSH3転写制御機構2010
- Author(s)
  李傑, 有田通恒, 児井稔, 逸見仁道
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591736
[Presentation] Transcriptional regulation of the hMLH1 gene by CXXC5, a zinc finger protein2009
- Author(s)
  有田通恒, 李傑, 菅野新一郎, 安井明, 逸見仁道
- Organizer
  The 32nd Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-21591736
[Presentation] A study in regulatory mechanism of the MSH3 gene expression2009
- Author(s)
  Li J, Min Z, Arita M, Koi M, Hemmi H
- Organizer
  The 32nd Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-21591736
[Presentation] A study in regulatory mechanism of the MSH3 gene expression2009
- Author(s)
  Li J, Min Z, Arita M, Koi M, Hemmi H
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21591736
[Presentation] DNAミスマッチ修復遺伝子MSH3によるEMAST腫瘍発生の分子機構
- Author(s)
  有田通恒
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場，マリンメッセ福岡（福岡）
- Data Source
  KAKENHI-PROJECT-22591495
[Presentation] 低酸素条件における大腸がん由来細胞でのEMASTの発生誘導
- Author(s)
  有田通恒, 久郷裕之，近藤元就，逸見仁道
- Organizer
  第72回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-24591985
[Presentation] DNAミスマッチ修復遺伝子MSH3によるEMAST腫瘍発生の分子機構
- Author(s)
  有田通恒, 児井稔，久郷裕之，近藤元就，逸見仁道
- Organizer
  第３５回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-24591985
[Presentation] Hypoxic down-regulation of DNA mismatch repair gene hMSH3 and genetic instability of colorectal cancer
- Author(s)
  Hemmi H, Arita M, Koike J, Kikuchi Y, Funahashi K, Ohhira T, Kugoh H, Kondo M
- Organizer
  71st Annual Meeting of Japanese Cancer Association (English oral session)
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-24591985
[Presentation] N-myc非増幅神経芽腫細胞が示すMAPK経路活性化を介した低酸素性N-myc発現増加と増殖亢進
- Author(s)
  有田通恒
- Organizer
  第55回日本小児血液・がん学会学術集会
- Place of Presentation
  ヒルトン福岡シーホーク（福岡）
- Data Source
  KAKENHI-PROJECT-25462071
[Presentation] 神経芽腫における低酸素下でのMAPK経路によるN-mycの活性化．
- Author(s)
  逸見仁道，有田通恒, 柴田祐充子, 岩崎維和夫，黒岩実，中川原　章、近藤元就
- Organizer
  第５４回日本小児血液・がん学会学術集会
- Place of Presentation
  パシフィコ横浜会議センター（神奈川）
- Data Source
  KAKENHI-PROJECT-24591985
[Presentation] N-myc非増幅神経芽腫細胞が示すMAPK経路活性化を介した低酸素性N-myc発現増加と増殖亢進
- Author(s)
  有田通恒, 酒井正人, 黒岩実, 近藤元就, 逸見仁道
- Organizer
  第５5回日本小児血液・がん学会学術集会
- Place of Presentation
  ヒルトン福岡シーホーク（福岡県）
- Data Source
  KAKENHI-PROJECT-24591985
[Presentation] Generation of EMAST in a colorectal cancer cell line under hypoxic condition
- Author(s)
  Michitsune Arita
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-25462071

1. HEMMI Hiromichi (90165514)

# of Collaborated Projects: 5 results

# of Collaborated Products: 23 results
2. KOIKE Junichi (30339155)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
3. FUNAHASHI Kiminiko (90297698)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SHIBUYA Kazutoshi (20196447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KANAZAWA Shinsaku (00408767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KANNO Shin-ichiro (10400417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 渡部洋 (80231009)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 竹原和宏 (20510374)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 刑部光正 (60400561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 齋藤俊章 (80162212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 小林陽一 (90205493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. LI Jie

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
13. YAMADA Kanae

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 久郷裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ARITA Michitsune 有田 通恒

有田 通恒 アリタ ミチツネ

Research Projects

Research Products

Co-Researchers

p53に依存した低酸素性DNAミスマッチ修復の根本的理解と進行大腸癌攻略への挑戦Principal Investigator

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Investigation of mechanism by which advanced colorectal cancer progresses EMAST-relating malignancy in hypoxiaPrincipal Investigator

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予後改善を目的としたEMAST卵巣癌の発生機構の解明

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Identification of responsible genes for advanced colorectal cancer: Development of in vitro system that mimics EMAST-related tumor-progression regulated by p53.Principal Investigator

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Identification of key factors to drive metastasis of progressive colorectal cancers: A search focusing transient players at early stage of metastasisPrincipal Investigator

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Investigation of an EMAST-generating tumor microenvironment and its relating malignant progression for colorectal cancerPrincipal Investigator

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Studies in molecular events of EMAST colorectal cancer and prognostic factors

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Molecular mechanism of transcriptional regulation forDNA repair genes: Identification of partner proteins for CXXC5, a novel MLH1 transcriptional factorPrincipal Investigator

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Molecular mechanism of hypoxia-induced genome instability in human colorectal cancer

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Development of easy procedure for determining MSI tumor and its application on diagnosis in colorectal cancer

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ミスマッチ修復遺伝子hMLH1の転写制御機構の解明:転写因子の同定とその異常検索Principal Investigator

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ミスマッチ修復遺伝子の転写制御機構の検討:転写因子の単離同定と役割の解明Principal Investigator

Principal Investigator

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Study for inactivation mechanism of tumor-associated genes in sporadic colorectal cancers

Principal Investigator

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ARITA Michitsune 有田通恒

有田通恒アリタミチツネ