UCHIDA Takafumi 内田隆史

Researcher Number	80312239
Other IDs	https://orcid.org/0000-0003-3665-4906
External Links
Affiliation (Current)	2025: 東京家政大学, 生活科学研究所, 研究員
Affiliation (based on the past Project Information) *help	2018 – 2019: 東京家政大学, 生活科学研究所, 研究員 2014 – 2018: 東北大学, 農学研究科, 教授 2012 – 2016: 東北大学, (連合)農学研究科(研究院), 教授 2010 – 2012: Tohoku University, 大学院・農学研究科, 教授 2008 – 2009: 東北大, (連合)農学研究科(研究院), 教授 … More 2008: Tohoku University, 大学院農学研究科, 教授 2007 – 2008: Tohoku University, Tohoku University, Graduate School of Agricultural Scinece, Professor 2006: 東北大学, 大学院農学研究科, 教授 2006: 東北大学, 大学院農学系研究科, 教授 2005: 東北大学, 大学院・農学研究科, 教授 2003 – 2004: Tohoku University, Center for Interdisciplinary Research, Associate Professor, 学際科学国際高等研究センター, 助教授 2001 – 2002: 東北大学, 加齢医学研究所, 助教授 Less
Review Section/Research Field	Principal Investigator Applied molecular and cellular biology / Applied molecular and cellular biology / Applied biochemistry / Biological Sciences / Cell biology / 食品科学・栄養科学 Except Principal Investigator Applied pharmacology / Bioorganic chemistry / Biological pharmacy / Applied molecular and cellular biology / Bioproduction chemistry/Bioorganic chemistry / Biological Sciences
Keywords	Principal Investigator Pin1 / Tau / アルツハイマー病 / Myc / 癌 / プロリン異性化酵素 / p53 / リン酸化 / Notch1 / 微小管 … More / Gas7 / ノックアウトマウス / Par14 / myc / 細胞周期 / 酵素 / 肥満 / Gas7b / リチウム / stat3 / アミロイド / タウ / P53 / 胸腺肥大 / 可視化 / 蛋白質 / NO / 生体機能利用 / AMPK / MDR / FOXO3 / 硝酸 / シグナル伝達 / 骨粗鬆症 / 加齢疾患 / 食品 / 脳神経疾患 / 再生医学 / 幹細胞 / 心臓疾患 / 血小板 / 健康長寿 / tau / ポリフェノール / FRET / Alzheimer''s disease / thymus / Amyloid / trans isomerase / peptidyl prolyl cis / プルセニリン / tat-Pin1 / プロテオーム / mcl1 / 胸腺 / Neurodenerative Disease / Cancer / Knock Out Mouse / Pint / 酵母 / cyclinD / ペプチジルプロリルイソメラーゼ / フォールディング / アポトーシス / インヒビター / がん遺伝子 / 神経原繊維変化 / 神経変性疾患 / 遺伝子欠損マウス / 細胞死 / 細胞膜透過 / 分化 / インテグリン / 脂肪細胞 / TAT-Pin1 / 細胞膜透過性Pin1 / 細胞分化 / 間葉系幹細胞 / 天然物資源 / 薬剤探索 / αシヌクレイン / 生活習慣病 / キネシン / リン酸化タウ / 機能調節剤 / 微小管関連タンパク質 / 微小管重合 / JNK / CAMKII / パクリタクセル / motility assay / コンデショナルノックアウトマウス / hGas7b / CREB / Pn1 / タンパク質・糖鎖工学 / 発生・分化制御 / 細胞機能 / Arp / spinal cord injury / oligodendrocyte / Alzheimer's disease / proteome / Alzheimer'sdlsease / high throughput screening / Smad / TGβ / Pinl / STAT / wwドメイン / QCM / リン酸化タンパク質 / プロリルイソメラーゼ / プリオン … More Except Principal Investigator Pin1 / maoecrystal V / JBIR-23 / enacyloxins / 全合成 / 単離構造決定 / 抗生物質 / リン酸化 / 増殖 / 肺動脈血管平滑筋 / Pin1阻害薬 / 肺高血圧 / 血管平滑筋細胞 / 肺動脈血管平滑筋細胞 / eNOS / 内皮型一酸化窒素合成酵素 / 肺動脈血管内皮細胞 / プロリン異性化酵素 / 肺高血圧症 / cortistain / echinopine / organocuprate / sanctolide A / thelepamide / sanctlide A / taxane / enacyloxin / sialidase / terpenoids / polyketides / marine products / antibitics / total synthesis / structure elucidation / 破骨細胞 / 骨芽細胞 / 骨粗鬆症 / 細胞周期 / p57Kip2 / 骨代謝 / アンチターミネーション / 温室効果ガス / 病原システム / ダイズ / 根粒菌 / エフェクター / タンパク質分泌系 / 脱窒 / 共生 / 生物間相互作用 / echinopines / Aspergillus puniceus / cortistatins / 抗性物質 / ステロイド / ポリケチド / テルペノイド / 海洋物質 / 天然物 / 構造活性相関 / タキサンジテルペノイド / ジャスモン酸 / 海洋天然物 / 植物毒素 / 制御 / モーター / タンパク質分子 / 生体ナノシステム / 細胞 / キネシン / ミオシン / ダイニン / ナノシステム Less

Role of Pin1 in the development of pulmonary hypertension and therapeutic application
- Principal Investigator
  
  SAKAI Satoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  University of Tsukuba
Is inducion of osteoblasts proliferation useful to treat the osteporosis patients?
- Principal Investigator
  
  Takahashi Katsuhiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hoshi University
Mechanisms of symbiotic evolution and N2O mitigation of soybean bradyrhizobia
- Principal Investigator
  
  Minamisawa Kiwamu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Tohoku University
Preparation for PTD-Pin1 and its appllication to stem cell differentiationPrincipal Investigator
- Principal Investigator
  
  Uchida Takafumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Tohoku University
Prevention, diagnosis and drug discovery of aging diseases using Pin1 related moleculesPrincipal Investigator
- Principal Investigator
  
  Uchida Takafumi
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Tokyo Kasei University
  Tohoku University
Development of agrochemical and pharmaceutical lead compounds based on the search and total synthesis of natural compounds with a unique structure and biological activity
- Principal Investigator
  
  Kiyota Hiromasa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Okayama University
Total synthesis and investigation of biologically active natural compounds with novel and complex structures and its application to the development of agricultural and pharmaceutical lead compounds
- Principal Investigator
  
  KIYOTA Hiromasa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Tohoku University
Drug Discovery of Alzheimer Disease from Molecules- Regulating Microtubule PolymerizationPrincipal Investigator
- Principal Investigator
  
  UCHIDA Takafumi
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Tohoku University
プロリン異性化酵素を標的とした薬剤Principal Investigator
- Principal Investigator
  
  内田隆史
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied biochemistry
- Research Institution
  Tohoku University
Regulation of Bio-nanosystems
- Principal Investigator
  
  HIGUCHI Hideo
- Project Period (FY)
  2004 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  Tohoku University
Integrated Mechanism Regulating Phosphorylation- Dependent Signal TransductionPrincipal Investigator
- Principal Investigator
  
  UCHIDA Takafumi
- Project Period (FY)
  2004 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Analysis of the stress resistance functions of Prolyl Isomerase Pin1Principal Investigator
- Principal Investigator
  
  UCHIDA Takafumi
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Tohoku University
リン酸化蛋白質の構造を変化させる新規蛋白質の発見Principal Investigator
- Principal Investigator
  
  内田隆史
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Tohoku University
プリオンを基質にするプロリルイソメラーゼの探索Principal Investigator
- Principal Investigator
  
  内田隆史
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  食品科学・栄養科学
- Research Institution
  Tohoku University
Biological Activities of Protein Folding EnzymePrincipal Investigator
- Principal Investigator
  
  UCHIDA Takafumi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Tohoku University

[Journal Article] Growth arrest specific protein 7 inhibits tau fibrillogenesis.2020
- Author(s)
  Shimizu, T., Hirose, K., Uchida, C., Uchida, T.
- Journal Title
  
  Biochem Biophy Res Commun,
  
  Volume: 526 Issue: 2 Pages: 281-286
- DOI
  10.1016/j.bbrc.2020.03.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18609, KAKENHI-PROJECT-26252064
[Journal Article] Prolyl isomerase Pin1 is required sperm production by promoting mitosis progression of spermatogonial stem cells.2018
- Author(s)
  Kurita-Suzuki A, Kamo Y, Uchida C, Tanemura K, Hara K, Uchida T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 497 Issue: 1 Pages: 388-393
- DOI
  10.1016/j.bbrc.2018.02.090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-25114004, KAKENHI-PROJECT-16H05220, KAKENHI-PROJECT-26252064
[Journal Article] Food polyphenols targeting peptidyl prolyl cis/trans isomerase Pin1.2018
- Author(s)
  Hidaka M, Kosaka K, Tsushima S, Uchida C, Takahashi K, Takahashi N, Tsubuki M, Hara Y, Uchida T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 499 Issue: 3 Pages: 681-687
- DOI
  10.1016/j.bbrc.2018.03.212
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05220, KAKENHI-PROJECT-17K08292, KAKENHI-PROJECT-17K18609, KAKENHI-PROJECT-26252064
[Journal Article] Expression of human mutant cyclin dependent kinase 4, Cyclin D and telomerase extends the life span but does not immortalize fibroblasts derived from loggerhead sea turtle (Caretta caretta).2018
- Author(s)
  Fukuda T, Eitsuka T, Donai K, Kurita M, Saito T, Okamoto H, Kinoshita K, Katayama M, Nitto H, Uchida T, Onuma M, Sone H, Inoue-Murayama M, Kiyono T.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 9229-9229
- DOI
  10.1038/s41598-018-27271-x
- NAID
  120006979734
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07803, KAKENHI-PROJECT-17K19426, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-15H01749, KAKENHI-PROJECT-17H03624, KAKENHI-PLANNED-25118005, KAKENHI-PROJECT-26252064, KAKENHI-PROJECT-16H05801
[Journal Article] MicroRNA-205-5p suppresses the invasiveness of oral squamous cell carcinoma by inhibiting TIMP-2 expression.2018
- Author(s)
  Nagai H, Hasegawa S, Uchida F, Terabe T, Ishibashi Kanno N, Kato K, Yamagata K, Sakai S, Kawashiri S, Sato H, Yanagawa T, Bukawa H.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 52 Pages: 841-850
- DOI
  10.3892/ijo.2018.4260
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05038, KAKENHI-PROJECT-15H05042, KAKENHI-PROJECT-16H05220, KAKENHI-PROJECT-26463038
[Journal Article] Prolyl Isomerase Pin1 Directly Regulates Calcium/Calmodulin-Dependent Protein Kinase II Activity in Mouse Brains2018
- Author(s)
  Shimizu Taiki、Kanai Kenta、Sugawara Yui、Uchida Chiyoko、Uchida Takafumi
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 9 Pages: 1351-1351
- DOI
  10.3389/fphar.2018.01351
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18609, KAKENHI-PROJECT-26252064
[Journal Article] Exercise habituation is effective for improvement of periodontal disease status: a prospective intervention study.2018
- Author(s)
  Omori S, Uchida F, Oh S, So R, Tsujimoto T, Yanagawa T, Sakai S, Shoda J, Tanaka K, Bukawa H.
- Journal Title
  
  Ther Clin Risk Manag
  
  Volume: 14 Pages: 565-574
- DOI
  10.2147/tcrm.s153397
- NAID
  120007134309
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19888, KAKENHI-PROJECT-16H03255, KAKENHI-PROJECT-17H02174, KAKENHI-PROJECT-16K15188, KAKENHI-PROJECT-16H05220
[Journal Article] Food polyphenols targeting peptidyl prolyl cis/trans isomerase Pin12018
- Author(s)
  M.Hidaka, K.Kosaka, S.Tsushima, C.Uchida, K.Takahashi, M.Tsubuki, N.Takahashi, Y.Hara, and T.Uchida
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07950
[Journal Article] Fluorescent resonance energy transfer -based biosensor for detecting conformational changes of Pin12018
- Author(s)
  Hidaka Masafumi、Okabe Emiko、Hatakeyama Kodai、Zook Heather、Uchida Chiyoko、Uchida Takafumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 505 Issue: 2 Pages: 399-404
- DOI
  10.1016/j.bbrc.2018.09.123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18609, KAKENHI-PROJECT-26252064
[Journal Article] Loss of Pin1 suppresses Hedgehog-driven medulloblastoma tumorigenesis.2017
- Author(s)
  Xu T, Zhang H, Park S, Venneti S, Kuick R, Ha K, Michael LE, Santi M, Uchida C, Uchida T, Srinivasan A, Dlugosz A, Olson J, Camelo-Piragua S, Rual JF
- Journal Title
  
  Neoplasisa
  
  Volume: 19 Pages: 216-225
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26660287
[Journal Article] Prolyl isomerase Pin1 promotes proplatelet formation of megakaryocytes via tau2017
- Author(s)
  Shimizu Taiki、Uchida Chiyoko、Shimizu Ritsuko、Motohashi Hozumi、Uchida Takafumi
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 493 Issue: 2 Pages: 946-951
- DOI
  10.1016/j.bbrc.2017.09.115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-15H04759, KAKENHI-PROJECT-16H05220, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-26252064
[Journal Article] Peptidyl-Prolyl Isomerase 1 Regulates Ca(2+) Handling by Modulating Sarco(Endo)Plasmic Reticulum Calcium ATPase and Na(2+)/Ca(2+) Exchanger 1 Protein Levels and Function.2017
- Author(s)
  Sacchi V, Wang BJ, Kubli D, Martinez AS, Jin JK, Alvarez R Jr, Hariharan N, Glembotski C, Uchida T, Malter JS, Yang Y, Gross P, Zhang C, Houser S, Rota M, Sussman MA
- Journal Title
  
  J Am Heart Assoc
  
  Volume: 493 Issue: 10
- DOI
  10.1161/jaha.117.006837
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05220, KAKENHI-PROJECT-26252064
[Journal Article] Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis2017
- Author(s)
  Xu Tao、Zhang Honglai、Park Sung-Soo、Venneti Sriram、Kuick Rork、Ha Kimberly、Michael Lowell Evan、Santi Mariarita、Uchida Chiyoko、Uchida Takafumi、Srinivasan Ashok、Olson James M.、Dlugosz Andrzej、Camelo-Piragua Sandra、Rual Jean-Fransois
- Journal Title
  
  Neoplasia
  
  Volume: 19 Issue: 3 Pages: 216-225
- DOI
  10.1016/j.neo.2017.01.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26252064, KAKENHI-PROJECT-16H05220
[Journal Article] Prolyl isomerase Pin1 regulates doxorubicin-inducible P-glycoprotein level by reducing Foxo3 stability.2016
- Author(s)
  T.Shimizu, Y.Bamba, Y.Kawabe, T.Fukuda, F.Fujimori, K.Takahashi, C.Uchida, and T.Uchida
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 471 Pages: 328-333
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07950
[Journal Article] MicroRNA-155-5p is associated with oral squamous cell carcinoma metastasis and poor prognosis2016
- Author(s)
  Osamu Baba,Shogo Hasegawa,Hiroki Nagai,Fumihiko Uchida,Masanobu Yamatoji,Naomi I. Kanno,Kenji Yamagata,Satoshi Sakai,Toru Yanagawa,Hiroki Bukawa
- Journal Title
  
  Journal of Oral Pathology & Medicine
  
  Volume: 45 Issue: 4 Pages: 248-255
- DOI
  10.1111/jop.12351
- NAID
  120007135548
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05038, KAKENHI-PROJECT-25293125, KAKENHI-PROJECT-15K15318, KAKENHI-PROJECT-16H05220
[Journal Article] Immunogenic properties of Landrace pigs selected for resistance to mycoplasma pneumonia of swine.2016
- Author(s)
  Borjigin L, Shimazu T, Katayama Y, Li M, Satoh T, Watanabe K, Kitazawa H, Roh S, Aso H, Katoh K, Uchida T, Suda Y, Sakuma A, Nakajo M and Suzuki K
- Journal Title
  
  Animal Science Journal
  
  Volume: 印刷中 Issue: 3 Pages: 321-329
- DOI
  10.1111/asj.12440
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26660287, KAKENHI-PROJECT-26252064, KAKENHI-PROJECT-15H04586, KAKENHI-PROJECT-16K15021
[Journal Article] Immunogenic properties of Landrace pigs selected for resistance to mycoplasma pneumonia of swine.2016
- Author(s)
  Borjigin L, Shimazu T, Katayama Y, Watanabe K, Kitazawa H, Roh S, Aso H, Katoh K, Uchida T, Suda Y, Sakuma A, Nakajo M and Suzuki K
- Journal Title
  
  Animal Science Journal
  
  Volume: 印刷中 Issue: 5 Pages: 638-645
- DOI
  10.1111/asj.12471
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26660287, KAKENHI-PROJECT-26252064, KAKENHI-PROJECT-15H04586, KAKENHI-PROJECT-16K15021
[Journal Article] 白血病治療薬剤ATRAの新規標的分子、プロリン異性化酵素Pin12016
- Author(s)
  高橋勝彦、内田千代子、内田隆史 :
- Journal Title
  
  血液内科
  
  Volume: 73 Pages: 491-496
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07950
[Journal Article] sNOOOpy, a Sensor for Physiological NO3－/NO2－ Employing a Bacterial Two-Component Regulatory System.2016
- Author(s)
  Hidaka M, Gotoh A, Shimizu T, Minamisawa K, Imamura H and Uchida T
- Journal Title
  
  Journal Biological Chemistry
  
  Volume: 291 Issue: 5 Pages: 2260-2269
- DOI
  10.1074/jbc.m115.687632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26660287, KAKENHI-PROJECT-26850042, KAKENHI-PUBLICLY-15H01401, KAKENHI-PROJECT-26252065, KAKENHI-PROJECT-26291027, KAKENHI-PROJECT-26252064
[Journal Article] Brown Algae polyphenol, a prolyl isomerase Pin1 inhibitor, prevents obesity by inhibiting the differentiation of stem cells into adipocytes.2016
- Author(s)
  Suzuki A, Saeki T, Ikuji H, Uchida C, Uchida T
- Journal Title
  
  Plos One
  
  Volume: 11(12) Issue: 12 Pages: e0168830-e0168830
- DOI
  10.1371/journal.pone.0168830
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26660287, KAKENHI-PROJECT-26252064
[Journal Article] Prolyl Isomerase Pin1 Regulates Doxorubicin- Inducible P-glycoprotein Level by Reducing Foxo3 Stability.2016
- Author(s)
  Shimizu T, Bamba Y, Kawabe Y , Fukuda T, Fujimori F, Takahashi K, Uchida C, and Uchida T
- Journal Title
  
  Biochemical Biophysical Research Communications
  
  Volume: 471 Issue: 2 Pages: 328-333
- DOI
  10.1016/j.bbrc.2016.02.014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26660287, KAKENHI-PROJECT-26252064, KAKENHI-PROJECT-16H05220
[Journal Article] The Protein Level and Transcription Activity of Activating Transcription Factor 1 is Regulated by Prolyl-isomerase Pin1 in Nasopharyngeal Carcinoma Progression.2016
- Author(s)
  Huang GL, Liao D, Chen H, Lu Y, Chen L, Li H, Li B, Liu W, Ye C, Li T, Zhu Z, Wang J, Uchida T, Zou Y, Don Z, He Z
- Journal Title
  
  Cell Death Dis
  
  Volume: 7(12) Issue: 12 Pages: e2571-e2571
- DOI
  10.1038/cddis.2016.349
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26660287, KAKENHI-PROJECT-26252064
[Journal Article] p62 modulates the intrinsic signaling of UVB-induced apoptosis.2016
- Author(s)
  Ito S, Kimura S, Warabi E, Kawachi Y, Yamatoji M, Uchida F, Ishibashi-Kanno N, Yamagata K, Hasegawa S, Shoda J, Tabuchi K, Sakai S, Bukawa H, Sekido M, Yanagawa T.
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 83 Issue: 3 Pages: 226-233
- DOI
  10.1016/j.jdermsci.2016.05.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H04917, KAKENHI-PROJECT-16H03255, KAKENHI-PROJECT-26282191, KAKENHI-PROJECT-26293284, KAKENHI-PROJECT-26293297, KAKENHI-PROJECT-26460485, KAKENHI-PROJECT-15K15037, KAKENHI-PROJECT-15K15488, KAKENHI-PROJECT-16K15188, KAKENHI-PROJECT-15K15318, KAKENHI-PROJECT-16H05220
[Journal Article] 白血病治療薬剤ATRAの新規標的分子、プロリン異性化酵素Pin12016
- Author(s)
  高橋勝彦、内田千代子、内田隆史
- Journal Title
  
  血液内科
  
  Volume: 73 Pages: 491-486
- Data Source
  KAKENHI-PROJECT-26252064
[Journal Article] Mycoplasma pneumonia of swine (MPS) resistance and immune characteristics of pig lines generated by crossing an MPS pulmonary lesion selected Landrace line and a highly immune capacity selected Large White line.2016
- Author(s)
  Borjigin L, Shimazu T, Katayama Y, Watanabe K, Kitazawa H, Roh SG, Aso H, Katoh K, Uchida T, Suda Y, Sakuma A, Nakajo M, Suzuki K
- Journal Title
  
  Animal Science Journal
  
  Volume: 印刷中 Issue: 8 Pages: 972-981
- DOI
  10.1111/asj.12529
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26660287, KAKENHI-PROJECT-26252064, KAKENHI-PROJECT-15H04586, KAKENHI-PROJECT-16K15021
[Journal Article] Inhibition of ASCT2 is essential in all-trans retinoic acid-induced reduction of adipogenesis in 3T3-L1 cells.2015
- Author(s)
  K. Takahashi, N. Uchida, C. Kitanaka, C. Sagara, M. Imai, and N. Takahashi,
- Journal Title
  
  FEBS Open Bio.
  
  Volume: 5 Pages: 571-578
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07950
[Journal Article] Pin1 Promotes Neuronal Death in Stroke by Stabilizing Notch Intracellular Domain2015
- Author(s)
  1.Baik SH, Fane M, Hyung PJ, Cheng YL, Yun UJ, Choi Y, Park JS, Chai B, Park JS, Back aik SH, Fane M, Hyung PJ, Cheng YL, Yun UJ, Choi Y, Park JS, Chai B, Park JS, Back SH, Jeong JI, Jang YJ, Bahn G, Lee JY, Li YI, Sobey C, Uchida T, Park JH, Kim HT, Tang S, Arumugam T and Jo DG.
- Journal Title
  
  Ann Neurol
  
  Volume: 77(3) Issue: 3 Pages: 504-516
- DOI
  10.1002/ana.24347
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26660287, KAKENHI-PROJECT-26252064
[Journal Article] Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunit2015
- Author(s)
  Nakatsu Y, Iwashita M, Sakoda H, Ono H, Nagata K, Matsunaga Y, Fukushima T, Fujishiro M, Kushiyama A, Kamata H, Takahashi S, Katagiri H, Honda H, Kiyonari H, Uchida T, Asano T
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 40 Pages: 24255-24266
- DOI
  10.1074/jbc.m115.658559
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09398, KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-26660287, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-25253067, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26670447, KAKENHI-PROJECT-26252064, KAKENHI-PROJECT-16H05220
[Journal Article] Phosphatidylethanolamine plasmalogen enhances the inhibiting effect of phosphatidylethanolamine on γ-secretase activity2015
- Author(s)
  Tomoko Onodera, Eugene Futai, Eiichiro Kan, Naoki Abe, Takafumi Uchida, Yoshiyuki Kamio and Jun Kaneko
- Journal Title
  
  Journal of Biochemistry,156,(2015)]
  
  Volume: 156 Issue: 5 Pages: 301-309
- DOI
  10.1093/jb/mvu074
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292043, KAKENHI-PROJECT-26660287, KAKENHI-PUBLICLY-26102504, KAKENHI-PROJECT-26252064
[Journal Article] Site-specific Phosphorylation of Tau Protein is Associated with Deacetylation of Microtubules in Mouse Spermatogenic Cells During Meiosis.2014
- Author(s)
  7.Inoue H, Hiradate Y, Shirakata Y, Kanai K, Kosaka K, Gotoh A, Fukuda Y, Nakai Y, Uchida T, Sato E and Tanemura K
- Journal Title
  
  FEBS Lett.
  
  Volume: 588, Issue: 11 Pages: 2003-2008
- DOI
  10.1016/j.febslet.2014.04.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26660287
[Journal Article] Neurotensin enhances sperm capacitation and the acrosome reaction　in　mice.2014
- Author(s)
  佐藤英明
- Journal Title
  
  BIOLOGY OF REPRODUCTION
  
  Volume: 91(2)53 Issue: 2 Pages: 1-9
- DOI
  10.1095/biolreprod.113.112789
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25660247, KAKENHI-PROJECT-26660287, KAKENHI-PROJECT-26252064
[Journal Article] Site-specific Phosphorylation of Tau Protein is Associated with Deacetylation of Microtubules in Mouse Spermatogenic Cells During Meiosis2014
- Author(s)
  Inoue H, Uchida T,Tanemura K
- Journal Title
  
  FEBS Lett
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] A High-Throughput Screen for Inhibitors of the Prolyl Isomerase, Pin1, Identifies a Seaweed Polyphenol that Reduces Adipose Cell Differentiation2014
- Author(s)
  Mori T, Uchida T.
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] The nitrate-sensing NasST system regulates nitrous oxide reductase and periplasmic nitrate reductase in Bradyrhizobium japonicum.2014
- Author(s)
  Sanchez, C., M. Itakura, T. Okubo, T. Matsumoto, H. Yoshikawa, A. Gotoh, M. Hidaka, T. Uchida, and K. Minamisawa.
- Journal Title
  
  Environmental Microbiology
  
  Volume: 16 Issue: 10 Pages: 3263-3274
- DOI
  10.1111/1462-2920.12546
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12F02398, KAKENHI-PROJECT-26252065, KAKENHI-PROJECT-26660287, KAKENHI-PROJECT-26252064
[Journal Article] Role of prolyl isomerase Pin1 in pathogenesis of diseases and remedy for the diseases from natural products2014
- Author(s)
  Takahashi K, Shimizu T, Kosaka K, Hidaka M, Uchida C, and Uchida T
- Journal Title
  
  Current Drug Target,
  
  Volume: 15 Pages: 973-981
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26252064
[Journal Article] Coffee consumption delays the hepatitis and suppresses the inflammation related gene expression in the Long-Evans Cinnamon rat2014
- Author(s)
  Katayama M, Uchida T, Fukuda T
- Journal Title
  
  Clin Nutr
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] A High-Throughput Screen for Inhibitors of the Prolyl Isomerase, Pin1, Identifies a Seaweed Polyphenol that Reduces Adipose Cell Differentiation2014
- Author(s)
  １．Mori T, Hidaka M , Ikuji H, Yoshizawa I, ToyoharaH, Okuda T, Uchida C, Asano T, Yotsu-Yamashita M and Uchida T
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] A high-throughput screen for inhibitors of the prolyl isomerase, Pin1, identifies a seaweed polyphenol that reduces adipose cell differentiation.2014
- Author(s)
  Mori T, Hidaka M, Ikuji H, Yoshizawa I, Toyohara H, Okuda T, Uchida C, Asano T, Yotsu-Yamashita M, Uchida T
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 78 Issue: 5 Pages: 832-838
- DOI
  10.1080/09168451.2014.905189
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25350109, KAKENHI-PROJECT-26292057, KAKENHI-PROJECT-26660094, KAKENHI-PROJECT-26660287, KAKENHI-PROJECT-26252064
[Journal Article] Primary fibroblast cultures and karyotype analysis for the olive ridley sea turtle (Lepidochelys olivacea)2014
- Author(s)
  Fukuda T, Katayama M. Kinoshita K. Kasugai T, Okamoto H. Kobayashi K. Kurita M. Soichi M. Douai K. Uchida T, Onuma M, Sone H, Isogai E. Inoue-Murayama M.
- Journal Title
  
  in vitro Leiluiar ana uevelopmentai biology -Animal-
  
  Volume: (In print) Issue: 5 Pages: 381-383
- DOI
  10.1007/s11626-013-9715-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J01484, KAKENHI-PROJECT-13J04781, KAKENHI-PROJECT-20228006, KAKENHI-PLANNED-25118005, KAKENHI-PROJECT-25290082
[Journal Article] Coffee consumption delays the hepatitis and suppresses the inflammation related gene expression in the Long-Evans Cinnamon rat2014
- Author(s)
  Masafumi Katayama, Kenichiro Donai, Hiroyuki Sakakibara, Yukiko Ohtomo, Makoto Miyagawa, Kengo Kuroda, Hiroko Kodama, Kazufumi Suzuki, Noriyuki Kasai, Katsuhiko Nishimori, Takafumi Uchida, Kouichi Watanabe, Hisashi Aso, Emiko Isogai, Hideko Sone, Tomokazu Fukuda
- Journal Title
  
  Clinical Nutrition
  
  Volume: 33 Issue: 2 Pages: 302-310
- DOI
  10.1016/j.clnu.2013.05.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J04781, KAKENHI-PROJECT-20228006
[Journal Article] Pin1 regulates osteoclast fusion through suppression of the master regulator of cell fusion DC-STAMP.2014
- Author(s)
  5.Islam R, Bae HS, Yoon WJ, Woo KM, Baek JH, Kim HH, Uchida T, and Ryoo HM
- Journal Title
  
  J Cell Physiol,
  
  Volume: 229 Issue: 12 Pages: 2166-2174
- DOI
  10.1002/jcp.24679
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26660287, KAKENHI-PROJECT-26252064
[Journal Article] Differential Regulation of Cellular Senescence and Differentiation by Prolyl Isomerase Pin1 in Cardiac Progenitor Cells2014
- Author(s)
  Toko H, Uchida T, Sussman MA
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Pages: 5348-5356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Par14 associates with IRS-1, thereby enhancing insulin-induced IRS-1 phosphorylation and metabolic actions2013
- Author(s)
  Zhang J, Uchida T, Asano T
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 20692-20701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Pin1 Stimulates Dephosphorylation of Tau at Cdk5-Dependent Alzheimer Phosphorylation Sites2013
- Author(s)
  Kimura T, Uchida T, Hisanaga S
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 7968-7977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Regulation of Cardiac Hypertrophic Signaling by Prolyl Isomerase Pin12013
- Author(s)
  8. Toko H, Konstandin MH, Doroudgar S, Ormachea L, Joyo E, Joyo AY, Din S, Gude NA, Collins B, Völkers MJ, Thuerauf DJ, Glembotski CC, Chen CH, Lu KP, Müller OJ, Uchida T, Sussman MA
- Journal Title
  
  Circ Res
  
  Volume: 112(9) Issue: 9 Pages: 1244-1252
- DOI
  10.1161/circresaha.113.301084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Pin1-mediated Runx2 modification is critical for skeletal development2013
- Author(s)
  Yoon WJ, Uchida T, Ryoo HM
- Journal Title
  
  J Cell Physiol
  
  Volume: 228 Pages: 2377-2385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Primary fibroblast cultures and karyotype analysis for the olive ridley sea turtle (Lepidochelys olivacea)2013
- Author(s)
  Fukuda T. Uchida T
- Journal Title
  
  In Vitro Cell Dev Biol Anim
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Growth arrest specific protein 7b (Gas7b) regulates neuronal cell morphology by enhancing microtubule and actin filament assembly2013
- Author(s)
  Gotoh A, Uchida T
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 34699-34706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Regulation of Cardiac Hypertrophic Signaling by Prolyl Isomerase Pin12013
- Author(s)
  Toko H, Uchida T, Sussman MA
- Journal Title
  
  Circ Res
  
  Volume: 112 Pages: 1244-1252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Isolation and structural determination of two novel phlorotannins from the brown alga Ecklonia kurome Okanura, and their radical scavenging activities2013
- Author(s)
  Yamashita YM, Uchida T
- Journal Title
  
  Mar Drugs
  
  Volume: 11 Pages: 165-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] p53 retards cell-growth and suppresses etoposide-induced apoptosis in Pin1-deficient mouse embryonic fibroblasts2012
- Author(s)
  Shimazaki K, Uchida T
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 422 Pages: 133-138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Efficient establishment of primary fibroblast cultures from the hawksbill sea turtle (Eretmochelys imbricata)2012
- Author(s)
  Fukuda T, Uchida T
- Journal Title
  
  In Vitro Cell Dev Biol Anim
  
  Volume: 48 Pages: 660-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] A critical step for JNK activation : Isomerization by the prolyl isomerase Pin12012
- Author(s)
  Park JE
- Journal Title
  
  Cell Death Differ
  
  Volume: 19 Issue: 1 Pages: 153-153
- DOI
  10.1038/cdd.2011.82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Establishment of an adipose-derived mesenchymal stem cell line from a p53-knockout mouse2012
- Author(s)
  13. Komine A, Abe M, Saeki T, Terakawa T, Uchida C and Uchida T
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 426 Issue: 4 Pages: 468-474
- DOI
  10.1016/j.bbrc.2012.08.094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] A critical step for JNK activation : Isomerization by the prolyl isomerase Pin12012
- Author(s)
  Park JE, Uchida T, Cho S
- Journal Title
  
  Cell Death Differ
  
  Volume: 19 Pages: 153-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Alzheimer's Disease-Related Protein hGas7b Interferes with Kinesin Motility2012
- Author(s)
  Hidaka M, Uchida T
- Journal Title
  
  J Biochem
  
  Volume: 151 Pages: 593-598
- NAID
  10031166101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Establishment of an adipose-derived mesenchymal stem cell line from a p53-knockout mouse2012
- Author(s)
  Komine A, Uchida T
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 426 Pages: 468-474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Relationship between the Structures of Taxane Derivatives and Their Microtubule Polymerization Activity2012
- Author(s)
  T. Koga, H. Kiyota, T. Horiguchi, Q.-W. Shi, K. Hirose, T. Uchida
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 76 Issue: 2 Pages: 349-352
- DOI
  10.1271/bbb.110797
- NAID
  10030400057
- ISSN
  0916-8451, 1347-6947
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580112
[Journal Article] Prolyl Isomerase Pin1 Regulates Mouse Embryonic Fibroblast Differentiation into Adipose Cells2012
- Author(s)
  Uchida T
- Journal Title
  
  PLoS One
  
  Volume: 7(3) Issue: 3 Pages: e31823-e31823
- DOI
  10.1371/journal.pone.0031823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006, KAKENHI-PROJECT-23701104
[Journal Article] Relationship between structure of Taxane derivatives and their microtubule polymerization activity2012
- Author(s)
  Hidaka M, Uchida T
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 76 Pages: 349-352
- NAID
  10030400057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Alzheimer's Disease-Related Protein hGas7b Interferes with Kinesin Motility2012
- Author(s)
  Hidaka M
- Journal Title
  
  J Biochem
  
  Volume: (未定)(掲載確定) Issue: 6 Pages: 593-598
- DOI
  10.1093/jb/mvs038
- NAID
  10031166101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Role of Pin1 in the pathogenesis of non-alcoholic steatohepatitis in a rodent model2012
- Author(s)
  Nakatsu Y, Uchida T Asano T
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 44526-44535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Efficient Establishment of Pig Embryonic Fibroblast Cell lines with Conditional Expression of the Simian Vacuolating Virus 40 Large T Fragment2012
- Author(s)
  Fukuda T, Uchida T
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 76 Pages: 1372-1377
- NAID
  10030982228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Identification of tuberculosis-associated proteins in whole blood supernatant2011
- Author(s)
  Tanaka T, Uchida T, Keicho N
- Journal Title
  
  BMC Infectious Diseases
  
  Volume: 11 Issue: 1 Pages: 71-71
- DOI
  10.1186/1471-2334-11-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006, KAKENHI-PROJECT-23500870
[Journal Article] Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 associates with IRS-1 and enhances insulin actions and adipogenesis2011
- Author(s)
  Nakatsu Y, Uchida T, Asano T
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 20812-20822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Quantifying the uncertainty of spontaneous Ca2+ oscillations in astrocytes: Particulars of ns in astrocytes : Particulars of Alzheimer's disease2011
- Author(s)
  Riera J, Uchida T, Kawashima R
- Journal Title
  
  Biophys J
  
  Volume: 101 Pages: 554-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] A dual inhibitor against prolyl isomerase Pin1 and cyclophilin discovered by a novel real-time fluorescence detection method2011
- Author(s)
  Mori, T, Uchida T
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 406 Pages: 439-443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] TIEG1 negatively controls the myoblast pool indispensable for fusion during myogenic differentiation of C2C12 cells2011
- Author(s)
  Miyake M, Uchida T, Yamaguchi T
- Journal Title
  
  J Cell Physiol
  
  Volume: 226 Pages: 1128-1136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] A dual inhibitor against prolyl isomerase Pinl and cyclophilin discovered by a novel real-time fluorescence detection method.2011
- Author(s)
  Mori, T, Hidaka M, Lin Y, Yoshizawa I, Okabe T, Egashira S, Kojima H, Nagano T, Koketsu M, Takamiya, M, Uchida T
- Journal Title
  
  Biochem.Biophys.Res.Commun. 406
  
  Pages: 439-443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Prolyl isomerase Pin1 protects mice from endotoxin shock2011
- Author(s)
  Akiyama H, Uchida T
- Journal Title
  
  PLoS One
  
  Volume: 6(2) Issue: 2 Pages: e14656-e14656
- DOI
  10.1371/journal.pone.0014656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Prolyl isomerase Pinl protects mice from endotoxin shock2011
- Author(s)
  Akiyama H, Misawa T, Ono M, Uchida C, Uchida T
- Journal Title
  
  PLoS One
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Pin1promotes TGF-beta-induced.9) migration and invasion2010
- Author(s)
  Matsuura I, Uchida T, Liu F
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 1754-1764
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Identification of Pin1-binding phosphorylated proteins in mouse brain2010
- Author(s)
  Tatara Y, Terakawa T, Uchida T
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 74 Pages: 2480-2483
- NAID
  10027728301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Preparation of protein transduction domain fused peptidyl prolyl cis/trans isomerase Pin12010
- Author(s)
  Ohashi T, Uchida T
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 74 Pages: 2067-2070
- NAID
  10027560590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Endocrine disrupting chemicals bind to a novel receptor, microtubule-associated protein 2, and positively and negatively regulate dendritic outgrowth in hippocampal neurons2010
- Author(s)
  Matsunaga, H, Uchida T, Ueda H
- Journal Title
  
  J Neurochem
  
  Volume: 114 Pages: 1333-1343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Pin1 associates with and induces translocation of CRTC2 to the cytosol, thereby suppressing CRE transcriptional activity2010
- Author(s)
  Nakatsu Y, Uchida T, Asano T
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 33018-33027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] hGas7b that promotes tubulin polymerization is decreased in Alzheimer's disease brain.2009
- Author(s)
  Akiyama H, Gotoh A, Shin RW, Koga T, Ohashi T, Sakamoto W, Arai H, Harada A, Sawa A, Uchida C, Uchida T
- Journal Title
  
  J Biol Chem 284
  
  Pages: 32695-32699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Dipentamethylene thiuram monosulfide is a novel inhibitor of Pin12009
- Author(s)
  Tatara Y, Lin YC, Bamba Y, Mori T and Uchida T
- Journal Title
  
  Biochem Biophys Res Commun 384
  
  Pages: 394-398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Use of a Real-time Fluorescence Monitoring System for High-Throughput Screening for Prolyl Isomerase Inhibitors2009
- Author(s)
  Mori T, Itami S, Yanagi T, Tatara Y, Takamiya M and Uchida T
- Journal Title
  
  J .Biomol Screen 14(4)
  
  Pages: 419-424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] The human actin-related protein hArp5 : Nucleo-cytoplasmic shuttling and involvement in DNA repair2009
- Author(s)
  Kitayama K, Kamo M, Oma Y, Matsuda R, Uchida T, Ikura T, Tashiro S, Ohyama T, Winsor B, Harata M
- Journal Title
  
  Exp Cell Res 315(2)
  
  Pages: 206-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Pin1 downregulates TGF-β signaling by inducing degradation of Smad proteins2009
- Author(s)
  Nakano A, Uchida T, Imamura T
- Journal Title
  
  J Biol Chem
  
  Volume: 284 Pages: 6109-6115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Effect of Pin1 or microtubule binding on dephosphorylation of FTDP-17 mutant tau2009
- Author(s)
  Yotsumoto K, Uchida T, Hisanaga S
- Journal Title
  
  J Biol Chem
  
  Volume: 284 Pages: 16840-16847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] hGas7b that promotes tubulin polymerization is decreased in Alzheimer's disease brain2009
- Author(s)
  Akiyama H, Uchida T
- Journal Title
  
  J Biol Chem
  
  Volume: 284 Pages: 32695-32699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Pin1 downregulates TGF-beta signaling by inducing degradation of Smad proteins2009
- Author(s)
  Nakano A, Koinuma D, Miyazawa K, Uchida T, Saitoh M, Kawabata M, Hanai J, Akiyama H, Abe M, Miyazono K, Matsumoto T, Imamura T
- Journal Title
  
  J Biol Chem 284
  
  Pages: 6109-6115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Direct Optical Microscopic Observation of the Microtubule Polymerization Intermediate Sheet Structure in the Presence of Gas7.2009
- Author(s)
  Uchida T, Akiyama H, Sakamoto W, Koga T, Yan, K., Uchida C, Hirose K, Itoh JT
- Journal Title
  
  J Mol Biol 391
  
  Pages: 849-857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] The peptidyl-prolyl isomerase Pin1 determines parathyroid hormone mRNA levels and stability in secondary hyperparathyroidism2009
- Author(s)
  Nechama M, Uchida T, Naveh-Many T
- Journal Title
  
  J Clin Invest
  
  Volume: 119 Pages: 3103-3114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Effect of Pin1 or microtubule binding on dephosphorylation of FTDP-17 mutant tau2009
- Author(s)
  Yotsumoto K, Saito T, Asada A, Oikawa1 T, Kimura T, Uchida C, Ishiguro K, Uchida T, Hasegawa M and Hisanaga S
- Journal Title
  
  J Biol Chem, (doi/10.1074/jbc.M109.003277) in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Use of a Real-time Fluorescence Monitoring System for High-Throughput Screening for Prolyl Isomerase Inhibitors2009
- Author(s)
  Mori T, Uchida T
- Journal Title
  
  J. Biomol Screen
  
  Volume: 14(4) Pages: 419-424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Dipentamethylene thiuram monosulfide is a novel inhibitor of Pin12009
- Author(s)
  Tatara Y, Uchida T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 384 Pages: 394-398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Direct Optical Microscopic Observation of the Microtubule Polymerization Intermediate Sheet Structure in the Presence of Gas72009
- Author(s)
  Uchida T
- Journal Title
  
  J Mol Biol
  
  Volume: 391 Pages: 849-857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] The peptidyl-prolyl isomerase Pinl determines parathyroid hormone mRNA levels and stability in secondary hyperparathyroidism.2009
- Author(s)
  Nechama M, Uchida T, Yosef-Levi IM, Silver J, Naveh-Many T
- Journal Title
  
  J Clin Invest 119
  
  Pages: 3103-3114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Onco-suppressor p53 protein prevents an Alzheimer disease mouse model, Pin1-null mouse from the increase of presenilin-12008
- Author(s)
  Takahashi K, Shimazaki K, Obama T, Kato R, Itabe H, Akiyama H. Uchida C, Shin RW, and Uchida T
- Journal Title
  
  New Frontiersin Lifestyle-Related Diseases, (Eds. Miyazaki, A and Imawari M), (Springer Japan, Doi : 10.1007/978-4-431-76428-1)
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Novel Functions of Prolyl Isomerase Pin12008
- Author(s)
  Akiyama H, Tatara Y and Uchida T
- Journal Title
  
  Tohoku J Agr Res 58
  
  Pages: 147-156
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Acid activation of protyrosinase from Aspergillus oryzae: homo-tetrameric protyrosinase is converted to active dimmers with an essential intersubunit disulfide bond at acididic pH2008
- Author(s)
  Tatara Y, Namba T, Yamagata, Y., Yoshida, T, Uchida, T. and Ichishima, E
- Journal Title
  
  Pigment Cell Res 21
  
  Pages: 89-96
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] The human actin-related protein hArp5 : Nucleo- cytoplasmic shuttling and involvement in DNA repair2008
- Author(s)
  Kitayama K, Uchida T, Harata M
- Journal Title
  
  Exp Cell Res
  
  Volume: 315(2) Pages: 206-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Pseudomonas fluorescens proliferates in a mouse organ homogenate at low temperature2008
- Author(s)
  Tatara Y, Terakawa T, Yamagata, Y. and Uchida T
- Journal Title
  
  Int J Mol Med 21
  
  Pages: 621-626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Acid activation of protyrosinase from Aspergillus oryzae : homo-tetrameric protyrosinase is converted to active dimmers with an essential intersubunit disulfide bond at acididic pH2008
- Author(s)
  Tatara Y, Uchida, T, Ichishima, E
- Journal Title
  
  Pigment Cell Melanoma Res
  
  Volume: 21 Pages: 89-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Acid activation of protyrosinase from Aspergillus oryzae : homo-tetrameric protyrosinase is converted to active dimmers with an essential intersubunit disulfide bond at acididic pH2008
- Author(s)
  Tatara Y, Namba T, Yamagata, Y., Yoshida, T, Uchida, T. and Ichishima, E
- Journal Title
  
  Pigment Cell Melanoma Res 21
  
  Pages: 89-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Pseudomonas fluorescens proliferates in a mouse organ homogenate at low temperature2008
- Author(s)
  Tatara Y, Uchida T
- Journal Title
  
  Int J Mol Med
  
  Volume: 21 Pages: 621-626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228006
[Journal Article] Proly1 isomerase Pin1: New findings on post-translational modifications and physiological substrates in cancer, Alzheimer''s disease and asthma2008
- Author(s)
  Takahashi K, Uchida C, Shin RW, Shimazaki, K and Uchida T.
- Journal Title
  
  Cell and Mol Life Sci. 65
  
  Pages: 359-375
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Pseudomonas fluorescens proliferates in a mouse organ homogenate at low temperature.2008
- Author(s)
  Tatara Y, Terakawa T, Yamagata, Y. and Uchida.
- Journal Title
  
  Int J Mol Med 21
  
  Pages: 621-626
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Prolyl isomerase Pin1 : New findings on post-translational modifications and physiological substrates in cancer, Alzheimer's disease and asthma2008
- Author(s)
  Takahashi K, Uchida C, Shin RW, Shimazaki,K and Uchida T
- Journal Title
  
  Cell and Mol Life Sci 65
  
  Pages: 359-375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Pin1 is required for the Ser727 phosphorylation-dependent Stat3 activity2007
- Author(s)
  Lufei C, Koh TH, Uchida T and Cao X
- Journal Title
  
  Oncogene 26
  
  Pages: 7656-7664
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Opposite regulation of oligodendrocyte apoptosis by JNK3 and Pin1 after spinal cord injury2007
- Author(s)
  Li M, Tep C, Yune Y, Zhou Z, Uchida T, Lu P, Yoon SO
- Journal Title
  
  J Neurosci 27
  
  Pages: 8395-8404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Topology of AspT, the aspartate: alanine antiporter of Tetragenococcus halophilus, determined by site-directed fluorescence labeling2007
- Author(s)
  Nanatani K, Fujiki T, Kanou K, Takeda-Shitaka M, Umeyama H, Ye L, Wang X, Nakajima T, Uchida T, maloney PC, Abe K.
- Journal Title
  
  J Bacteriol 189
  
  Pages: 7089-7097
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Safe and Handy Fluorescent Stain Imager for Proteome Analysis2007
- Author(s)
  Terakawa T, Keicho N, Uchida C and Uchida T
- Journal Title
  
  Current Proteomics 4
  
  Pages: 115-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Ablation of a peptidyl prolyl isomerase Pin1 from p53-null mice accelerated thymic hyperplasia by increasing the level of the intracellular form of Notch12007
- Author(s)
  Takahashi K, Akiyama H, Shimazaki K, Uchida C, Akiyama OH, Tomita M, Fukumoto M, and Uchida T
- Journal Title
  
  Oncogene 26
  
  Pages: 3835-3845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Opposite regulation of oligodendrocyte apoptosis by JNK3 and Pin1 after spinal cord injury2007
- Author(s)
  Li M, Tep C, Yune Y, Zhou Z, Uchida T, Lu P, Yoon So.
- Journal Title
  
  J Neurosic 27
  
  Pages: 8395-8404
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Topology of AspT, the aspartate:alanine antiporter of Tetragenococcus halophilus, determined by site-directed fluorescence labeling2007
- Author(s)
  Nanatani K, Fujiki T, Kanou K, Takeda-Shitaka M, Umeyama H, Ye L, Wang X, Nakajima T, Uchida T, Maloney PC, Abe K
- Journal Title
  
  J Bacteriol 189
  
  Pages: 7089-7097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Pin1 is required for the Ser727 phosphorylation- dependent Stat3 activity2007
- Author(s)
  Lufei C, Koh TH, Uchida T and Cao X
- Journal Title
  
  Oncogene 26
  
  Pages: 7656-7664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Ablation of a peptidy1 proly1 isomerase Pin1 from p53-null mice accelerated thymic hyperplasia by increasing the level of the intracellular form of Notch 12007
- Author(s)
  Takahashi K, Akiyama H, Shimazaki K, Uchida C, Akiyama OH, Tomita M, Fukumoto M, and Uchida T
- Journal Title
  
  Oncogene 26
  
  Pages: 3835-3845
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Safe and Handy Fluorescent Stain Imager for Proteome Analysis2007
- Author(s)
  Terakawa T, Keicho N, Uchida C and Uchida T.
- Journal Title
  
  Current Proteomics 4
  
  Pages: 115-120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Membrane Topology of Aspartate: Alanine Antiporter AspT from Comamonas testosteroni.2007
- Author(s)
  Fujiki T, Nanatani K, Nishitani K, Yagi K, Ohnishi F, Yoneyama H, Uchida T, Nakajima T, Abe K
- Journal Title
  
  J Biochem 141
  
  Pages: 85-91
- NAID
  10020102081
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Membrane Topology of Aspartate:Alanine Antiporter AspT from Comamonas testosteroni2007
- Author(s)
  Fujiki T, Nanatani K, Nishitani K, Yagi K, Ohnishi F, Yoneyama H, Uchida T, Nakajima T, Abe K
- Journal Title
  
  J Biochem 141
  
  Pages: 85-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Follicle-stimulating hormone (FSH) stimulates the expression of Pin1, a peptidy1-proly1 isomerase, in the bovine granulosa cells2006
- Author(s)
  Shimizu T, Tetsuka M, Miyamoto A and Uchida T
- Journal Title
  
  Domest Anim Endocrinol. 32
  
  Pages: 226-234
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] 認知症のメカニズムに迫る Pin1 とアルツハイマー病の病態2006
- Author(s)
  辛龍雲、秋山弘匡、内田隆史
- Journal Title
  
  化学と生物 44,7
  
  Pages: 447-452
- NAID
  10017994673
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Comparative analysis of enzyme activities and mRNA levels of peptidyl prolyl cis/trans isomerases in various organs of wild type and Pin1-/- mice2006
- Author(s)
  Fanghanel J, Akiyama H, Uchida C and Uchida T
- Journal Title
  
  FEBS Lett 580
  
  Pages: 3227-3245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Expression of Pin1, A Peptidyl Prolyl Isomerase, in the Ovaries of eCG/hCG-treated Immature Female Mice2006
- Author(s)
  Shimizu T, Akiyama H, Abe Y, Sasada H, Sato E, Miyamoto A and Uchida T
- Journal Title
  
  J Reprod Dev 52
  
  Pages: 287-291
- NAID
  120006390132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Comparative analysis of enzyme activities and mRNA levels of peptidy1 proly1 cis/trans isomerases in various organs of wild type and Pin1 -/- mice2006
- Author(s)
  Fanghanel J, Akiyama H, Uchida C and Uchida T
- Journal Title
  
  FEBS Lett 580
  
  Pages: 3227-3245
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Hydrophobic interactions between the secondary structures on the molecular surface reinforce the alkaline stability of serine protease2006
- Author(s)
  Oguchi Y, Maeda H, Abe K, Nakajima T, Uchida T and Yamagata Y
- Journal Title
  
  Biotechnol Lett 28
  
  Pages: 1383-1391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Novel mechanism undering dementia-Pin1 and Alzheimer's disease2006
- Author(s)
  Shin RW, Akiyama H and uchida T
- Journal Title
  
  Chem and Biol (Japanese) 44
  
  Pages: 447-452
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Follicle- stimulating hormone (FSH) stimulates the expression of Pin1, a peptidyl-prolyl isomerase, in the bovine granulosa cells2006
- Author(s)
  Shimizu T, Tetsuka M, Miyamoto A and Uchida T
- Journal Title
  
  Domest Anim Endocrinol 32
  
  Pages: 226-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Hydrophobic interactions between the secondary structures ont he molecular surface reinforce the alkaline stability of serine protease2006
- Author(s)
  Oguchi Y, Maeda H, Abe K, nakajima T, Uchida T and Yamagata Y
- Journal Title
  
  Biotechnol Lett 28
  
  Pages: 1383-1391
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] 加齢疾患を制御するプロリン異性化酵素Pin12005
- Author(s)
  内田隆史等
- Journal Title
  
  PNE 50(11)
  
  Pages: 1413-1419
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] 加齢疾患を抑制するプロリン異性化酵素Pin12005
- Author(s)
  内田隆史 Joerg Fanghaenel、内田千代子、Linnaea Ostroff
- Journal Title
  
  タンパク核酸酵素, (共立出版) Vol50, No.11
  
  Pages: 1413-1419
- NAID
  40006927837
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Proly1 isomerase Pin1 facilitates production of Alzheimer's amyloid beta from beta-cleaved amyloid precursor protein2005
- Author(s)
  Akiyama H, Shin R, Uchida C, Kitamoto T and UchidaT
- Journal Title
  
  Biochem Biophys Res Commun(Corrigendum; Nature(2007)446,342) 336
  
  Pages: 521-529
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Prolyl isomerase Pin1 facilitates production of Alzheimer's amyloid beta from beta-cleaved amyloid precursor protein2005
- Author(s)
  Akiyama H, Shin R, Uchida C, Kitamoto T and UchidaT
- Journal Title
  
  Biochem Biophys Res Commun, (Corrigendum ; Nature (2007)446, 342) 336
  
  Pages: 521-529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] 加齢疾患を制御するプロリン異性化酵素Pin12005
- Author(s)
  内田隆史等
- Journal Title
  
  PNE 50(11)
  
  Pages: 1413-1419
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] 加齢疾患を制御するプロリン異性化酵素Pin12005
- Author(s)
  内田隆史等
- Journal Title
  
  PNE 50(11)
  
  Pages: 1413-1419
- Data Source
  KAKENHI-PROJECT-15657043
[Journal Article] Enzyme regulating ageing, proly1 isomerase Pin12005
- Author(s)
  Uchida T, Fangaenel J, Uchida C and Ostroff L
- Journal Title
  
  PNE (Japanese) 50(11)
  
  Pages: 1413-1419
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] リン酸化タンパク質の構造と機能を制御する因子の生物活性2004
- Author(s)
  内田隆史
- Journal Title
  
  Molecular Medicine 41(5)
  
  Pages: 518-521
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Cytochrome P450 gene expression levels in peripheral blood mononuclear cells in comparison with the liver2004
- Author(s)
  Furukawa, M., Nishimura, M., Ogino, D., Chiba, R., Ikai, I., Ueda, N., Naito, S., Kuribayashi, S., Moustafa, MA, Uchida, T., Sawada, H., Kamataki, T., Funae, Y., Fukumoto, M
- Journal Title
  
  Cancer Sci 95(6)
  
  Pages: 520-529
- NAID
  10013723642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] A signaling pathway controlling myc degradation that impacts oncogenic transformation of human cells2004
- Author(s)
  Yeh, E, Cunnigham, M., Arnold, H., Chasse, D., Monteith, T., Ivaldi, G., Hahn, WC., Stukenberg, T., Shenolikar, S., Uchida, T., Counter, CM., Nevins, JR., Means, AR. And Sears, R
- Journal Title
  
  Nature Cell Biol 6(4)
  
  Pages: 308-318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] リン酸化タンパク質の構造と機能を制御する因子の生物活性2004
- Author(s)
  内田隆史
- Journal Title
  
  Molecular Medicine 41(5)
  
  Pages: 518-521
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] リン酸化タンパク質調節因子Pin1による癌およびアルツハイマー病の制御2004
- Author(s)
  内田隆史
- Journal Title
  
  Molecular Medicine 41(5)
  
  Pages: 538-543
- Data Source
  KAKENHI-PROJECT-15657043
[Journal Article] Comparative analysis of ATP-binding cassette (ABC) transporter gene expression levels in peripheral blood leukocytes and in liver with hepatocellular carcinoma2004
- Author(s)
  Moustafa, MA., Ogino, D., Nishimura, M., Ueda, N., Naito, S., Furukawa, M., Uchida, T., Ikai, I., Sawada, H., Fukumoto, M
- Journal Title
  
  Cancer Sci 95(6)
  
  Pages: 530-536
- NAID
  10013723669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] リン酸化タンパク質調節因子Pin1 による癌およびアルツハイマー病の制御, 特集「タンパク質リン酸化調節異常と疾患」2004
- Author(s)
  内田隆史
- Journal Title
  
  Molecular Medicine, (内田隆史編) 41(5)
- NAID
  40006185286
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Control of cancer and Alzheimer's disease by phosphorylated protein regulatory Enzyme, Pin12004
- Author(s)
  Uchida T
- Journal Title
  
  Molecular Medicine (Japanese) 42(5)
  
  Pages: 538-543
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] リン酸化タンパク質調節因子Pin1による癌およびアルツハイマー病の制御2004
- Author(s)
  内田隆史
- Journal Title
  
  Molecular Medicine 41(5)
  
  Pages: 538-543
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] 微小管の重合・脱重合 : 原子から細胞そして個体へ癌・アルツハイマー病とリン酸化調節因子Pin12004
- Author(s)
  内田隆史
- Journal Title
  
  生物物理,44巻,(Suppl.1)
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] リン酸化タンパク質の構造と機能を制御する因子の生物活性2004
- Author(s)
  内田隆史
- Journal Title
  
  Molecular Medicine 41(5)
  
  Pages: 518-521
- Data Source
  KAKENHI-PROJECT-15657043
[Journal Article] Cytochrome P450 Gene expression levels in peripheral blood mononuclear cells in comparison with the liver2004
- Author(s)
  Furukawa, M., Nishimura, M., Ogino, D., Chiba, R., Ikai, I., Ueda, N., Naito, Kuribayashi, S., Moustafa, MA. Uchida, T., Sawada, H., Kamataki, T., Funae, Y., Fukumoto, M.
- Journal Title
  
  S, Cancer Sci. 95(6)
  
  Pages: 520-529
- NAID
  10013723642
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Comparative analysis of ATP-binding cassette (ABC) transporter gene expression levels in peripheral blood leukocytes and in liver with hepatocellular carinoma2004
- Author(s)
  Moustafa, MA., Ogino, D., Nishimura, M., ueda, N., Naito, S., Furukawa, M. Uchida, T., Ikai, I.., Sawada, H., Fukumoto, M.
- Journal Title
  
  Cancer Sci. 95(6)
  
  Pages: 530-536
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] A signaling pathway controlling myc degradation that impacts oncogenic transformation of human cells2004
- Author(s)
  Yeh, E, Cunnigham, M. Arnold, H. Chasse, D., Moteith, T., Ivaldi, G., Hahn, WC., Stukengerg, T., Shenolikar, S., Uchida, T., Counter, CM.,Nevins, JR., Means, AR. And Sears R.
- Journal Title
  
  Nature Cell Biol. 6(4)
  
  Pages: 308-318
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] リン酸化タンパク質調節因子Pin1による癌およびアルツハイマー病の制御2004
- Author(s)
  内田隆史
- Journal Title
  
  Molecular Medicine 41(5)
  
  Pages: 538-543
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Journal Article] Overview リン酸化タンパク質の構造と機能を制御する因子の生物活性, 特集「タンパク質リン酸化調節異常と疾患」2004
- Author(s)
  内田隆史
- Journal Title
  
  Molecular Medicine, (内田隆史編) 41(5)
  
  Pages: 518-521
- NAID
  40006185283
- Data Source
  KAKENHI-PROJECT-16083202
[Journal Article] Functions of enzyme regulating the structure and function of phosphorylated proteins2004
- Author(s)
  Uchida T
- Journal Title
  
  Molecular medicine (Japanese) 41(5)
  
  Pages: 518-521
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Presentation] Pin 1 gene deficient mice impair spatial cognitive function and increase amyloid formation in the brain2019
- Author(s)
  大滝博和, 田中優希, 内田隆史 et al
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] Pin1 gene deficient mice impaired spatial cognitive function and showed a decrease of frontotemporal lobar.2019
- Author(s)
  Ohtaki H eH. OHTAKI1, Y. TANAKA1, T. UCHIDA　et al
- Organizer
  Neuro 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] Pin1 gene deficient mice impair spatial memory and show small brain volume2019
- Author(s)
  H. OHTAKI1, Y. TANAKA1, T. UCHIDA　et al
- Organizer
  Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] tau と相互作用する Gas7 の機能解析2018
- Author(s)
  清水泰希、藤田彩子、内田隆史
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] tau 凝集における Gas7 の役割について2018
- Author(s)
  清水泰希、内田隆史
- Organizer
  au 研究ミーティング
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] Pin1 and Par14 prolyl isomerase inhibitors block oral cancer cell proliferation2017
- Author(s)
  H. Miyashita, S Mori, T. Takahashi, T. Uchida
- Organizer
  oral & maxillofacial surgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] Pin1による tauを介した巨核球胞体形成制御機構2017
- Author(s)
  清水泰希、菅原佑衣、広瀬恵子、清水律子、本橋ほづみ、内田千代子、内田隆史
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] アミノ酸による脂肪細胞のPin1活性量調節2017
- Author(s)
  高橋勝彦、片桐啓暁、清水愛、和泉田有望、福田翔大、高橋典子、内田隆史、東伸昭
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] Pin1阻害作用のある褐藻類ポリフェノールは PPARγ レベルを低下させることでマウスの肥満を抑制した2017
- Author(s)
  岡田拓実、鈴木充子、生地紘子、内田隆史
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] Pin1peptidyl prolyl isomerase inhibitors block cancer proliferation2017
- Author(s)
  H. Miyashita, T. Takahashi, T. Uchida
- Organizer
  日本頭頚部癌学会大会
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] in1 Functions during early cleavage in mouse embryo2017
- Author(s)
  Hoshino Y, Miyamoto T, Kawai T, Uchida T, Shimada M
- Organizer
  World Congress of Reproductive Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] Par14の細胞周期進行制御機能の解明2017
- Author(s)
  竹原一真、内田隆史
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] MRIによるPin1遺伝子欠損マウスの脳の容量の解析2017
- Author(s)
  発表者；大滝博和、渡邊潤、矢倉一道、宮本和幸、土肥謙二、内田隆史、本田一穂
- Organizer
  第122回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] Establishment of mesenchymal stem cell line from p53-deleted mouse and its application to drug discovery2017
- Author(s)
  Uchida T, Miyashita T, Suzuki T, Suzuki A, Uchida C
- Organizer
  Bioprocessing summit
- Place of Presentation
  Boston,　USA
- Year and Date
  2017-08-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] アミノ酸による脂肪細胞の Pin1 活性量調節2017
- Author(s)
  高橋勝彦、片桐啓暁、清水愛、和泉田有望、福田翔大、高橋典子、内田隆史、東伸昭
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-15K07950
[Presentation] Pin1によるFoxO3を介したP-glycoproteinの発現制御機構2017
- Author(s)
  清水泰希、坂場義正、川邉庸介、内田隆史
- Organizer
  日本農芸化学会
- Place of Presentation
  京都女子大学（京都府・京都市）
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] プロリン異性化酵素Pin1による着床前初期胚発生に果たす役割2016
- Author(s)
  星野由美、川合智子、内田隆史、島田昌之
- Organizer
  第34回日本受精着床学会総会・学術講演会
- Place of Presentation
  軽井沢プリンスホテルウエスト（長野県・軽井沢町）
- Year and Date
  2016-09-15
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] c-Mycとの相互作用によるPin1の構造変化を解析できるFRET法の確立2016
- Author(s)
  畠山皓大, 岡部恵美子、日高将文、内田隆史
- Organizer
  第89回日本生化学会
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] 卵子の形成・成熟、受精後の初期胚発生過程におけるプロリン異性化酵素Pin1の発現と機能2016
- Author(s)
  星野由美、川合智子、内田隆史、島田昌之
- Organizer
  第57回日本卵子学会
- Place of Presentation
  新潟コンベンションセンター（新潟県・新潟市）
- Year and Date
  2016-05-14
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] プロリン異性化酵素Pin1は受精卵の卵割に機能する2016
- Author(s)
  星野由美、宮本拓真、川合智子、内田隆史、島田昌之
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] Pin1はCamKIIの活性を低下させることでTauの機能制御を行う2016
- Author(s)
  菅原佑衣、金井研太、清水泰希、広瀬恵子、日高将文、内田千代子、内田隆史
- Organizer
  第89回本生化学会大会
- Place of Presentation
  仙台国際会議センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] Pin1はCamKIIの活性を低下させることでTauの機能制御を行う2016
- Author(s)
  菅原佑衣、金井研太、清水泰希、広瀬恵子、日高将文、内田千代子、内田隆史
- Organizer
  第89回日本生化学会
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] 卵子の形成・成熟、受精後の初期胚発生過程におけるプロリン異性化酵素Pin1の発現と機能2016
- Author(s)
  星野由美、川合智子、内田隆史、島田昌之
- Organizer
  第57回日本卵子学会
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] プロリン異性化酵素Pin1 阻害ポリフェノールの発見2016
- Author(s)
  對馬早織、日高將文、高橋典子、津吹政可、内田隆史
- Organizer
  日本農芸化学会2016年大会
- Place of Presentation
  札幌コンベンションセンター（北海道、札幌市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] Growth arrest specific protein 7bによる微小管関連蛋白質Tauの制御2016
- Author(s)
  清水泰希、藤田彩子、後藤愛那、日高將文、内田隆史
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際会議センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] プロリン異性化酵素Pin1阻害剤である褐藻ポリフェノールによる脂肪由来間葉系幹細胞の脂肪細胞への分化抑制2016
- Author(s)
  鈴木充子、佐伯俊之、内田隆史、内田千代子
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際会議センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] プロリン異性化酵素Pin1は受精卵の卵割に機能する2016
- Author(s)
  星野由美、宮本拓真、川合智子、内田隆史、島田昌之
- Organizer
  第38回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] Growth arrest specific protein 7bによる微小管関連蛋白質Tauの制御2016
- Author(s)
  清水泰希、藤田彩子、後藤愛那、日高將文、内田隆史
- Organizer
  第89回日本生化学会
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] c-Mycとの相互作用によるPin1の構造変化を解析できるFRET法の確立2016
- Author(s)
  畠山皓大, 岡部恵美子、日高将文、内田隆史
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際会議センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] Establishment of mesenchymal stem cell line from p53-deleted mouse and its application to drug discovery2016
- Author(s)
  Uchida T, Miyashita T, Suzuki T, Suzuki A, Uchida C
- Organizer
  Bioprocessing summit
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] Crisper/Cas9 法によるPin1-欠損ヒト細胞の作製と解析2016
- Author(s)
  秋吉皓太、イ　タツチュウ;、カスジャンマシュー、内田隆史
- Organizer
  日本農芸化学会2016年大会
- Place of Presentation
  札幌コンベンションセンター（北海道、札幌市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] プロリン異性化酵素Pin1による着床前初期胚発生に果たす役割2016
- Author(s)
  星野由美、川合智子、内田隆史、島田昌之
- Organizer
  第34回日本受精着床学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] プロリン異性化酵素Pin1阻害剤である褐藻ポリフェノールによる脂肪由来間葉系幹細胞の脂肪細胞への分化抑制2016
- Author(s)
  鈴木充子、佐伯俊之、内田隆史、内田千代子
- Organizer
  第89回日本生化学会
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] Regulation of nitrous oxide reductase genes by the NasST system in Bradyrhizobium diazoefficiens2015
- Author(s)
  Cristina Sanchez, Manabu Itakura, Takashi Okubo, Takashi Matsumoto, Hirofumi Yoshikawa, Aina Gotoh, Masafumi Hidaka, Takafumi Uchida, Kiwamu Minamisawa
- Organizer
  20th European Nitrogen Cycle Meeting
- Place of Presentation
  The University of Aberdeen (UK)
- Year and Date
  2015-09-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26252065
[Presentation] Pin1による巨核球膜構造変化制御2015
- Author(s)
  清水泰希、鈴木伸幸、本橋ほづみ、内田隆史
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県、神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] Pin1によるタウキナーゼ活性制御の解析2015
- Author(s)
  馬場貴大, 金井研太, 日高將文, 内田隆史
- Organizer
  農芸化学会
- Place of Presentation
  岡山大学
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] Pin1 gene deficient mice impaired spatial cognitive function and exhibited frontotemporal lobar atrophy2015
- Author(s)
  大滝博和、桐山恵介、渡邊潤、山本麗奈、松本皆子、高橋勝彦、内田隆史、塩田清二
- Organizer
  日本解剖学会総会・全国学術集会・日本生理学会大会合同大会（
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] 海藻ポリフェノールはPin1活性を阻害しマウスの脂肪量を低下させた2015
- Author(s)
  鈴木充子、宮下拓也、秋吉皓太、鈴木寿弥、日高将文、内田隆史、内田千代子
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県、神戸市）
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] Pin1は脂肪由来間葉系幹細胞の分化を促進させた2015
- Author(s)
  鈴木寿弥、鈴木充子、宮下拓也、佐伯俊幸、阿部素子、内田隆史
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県、神戸市）
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-26252064
[Presentation] 根粒菌の二成分制御システムを利用したNO3－/NO2－バイオセンサーの開発2014
- Author(s)
  後藤愛那、日高將文、清水泰希、板倉学、クリスチーナ・サンチェス、南澤究、今村博臣、内田隆史
- Organizer
  日本生化学会大会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] Improvement of FRET based indicator for structural change of Pin12014
- Author(s)
  岡部恵美子、日高將文、内田隆史
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜国際会議場
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] Growth arrest specific protein b(Gas7b)によるリン酸化Tau量の調節機構2014
- Author(s)
  乗田理恵、清水泰希、秋山弘匡、広瀬恵子、後藤愛那、日高將文、内田隆史
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  東京、明治大学
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] FRETを用いた硝酸センサータンパク質の開発2014
- Author(s)
  後藤愛那日高將文岡部恵美子金井研太小坂啓太板倉学クリスチーナサンチェス南澤究内田隆史
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  東京, 明治大学
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] プロリン異性化酵素Pin1によるP糖タンパク質の発現制御機構の解析2014
- Author(s)
  川邉庸介、坂場義正、内田隆史
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  東京、明治大学
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] ポリフェノールによるプロリン異性化酵素(Pin1、Cyp)の活性制御2014
- Author(s)
  小坂啓太、生地紘子、日高將文、内田隆史
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  東京、明治大学
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] FRET法を用いたPin1構造変化の可視化2014
- Author(s)
  岡部恵美子、日高將文、内田隆史
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  東京、明治大学
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] Pin1/p53ダブルノックアウトマウス由来　脂肪由来間葉系幹細胞株の樹立と解析2014
- Author(s)
  佐伯俊幸、鈴木寿弥、秋吉皓太、阿部素子、内田隆史
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜国際会議場
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] プロリン異性化酵素Pin1による脳内CaMKIIの活性と安定性制御2014
- Author(s)
  金井研太、馬場貴大、日高將文、内田隆史
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜国際会議場
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] Pin1阻害剤としてのポリフェノール類の構造・機能相関2014
- Author(s)
  小坂啓太、生地絋子、日高將文、内田隆史
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜国際会議場
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-26660287
[Presentation] プロリン異性化酵素Pin1阻害剤のハイスループットスクリーニングによる、脂肪細胞分化抑制効果を有する海藻ポリフェノールの同定2013
- Author(s)
  森正、林宜瑾、吉澤いぶき、生地紘子、田村隆裕、奥田徹、内田千代子、豊原治彦、山下まり、内田隆史
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  仙台市、東北大学
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] 化合物ライブラリーを用いたアカデミア創薬の東北大学における取り組み2013
- Author(s)
  菅原明、青木淳賢、段孝、清水律子、鈴木教郎、可野邦行、奥平真一、箱田明子、金子寛、内田隆史、中澤徹、土井隆行、宮田敏男、大島吉輝、山本雅之
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡市、国際会議場
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] p53KOマウス脂肪由来クローナル間葉系幹細胞の樹立と解析2013
- Author(s)
  佐伯俊幸、阿部素子、小峰陽比古、内田千代子、内田隆史
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  仙台市、東北大学
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] プロリン異性化酵素Pin1はPresenilin1に結合し、活性を制御する2013
- Author(s)
  佐々木広美、二井勇人、内田隆史
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  仙台市、東北大学
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] Significance of Pin1- Knock Out Mouse Creation Speaker2013
- Author(s)
  Uchida T
- Organizer
  International symposium on "Cyclophilins and other Foldases : Cell Siganaling Catalysts and Drug Targets"
- Place of Presentation
  Halle, Germany
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] プロリン異性化酵素Pin1の脳関連キナーゼCaMKIIへの影響2013
- Author(s)
  金井研太、小坂啓太、堤貴明、後藤愛那、二井勇人、日高將文、内田隆史
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  仙台市, 東北大学
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] アルツハイマー病関連タンパク質Gas7bの機能2013
- Author(s)
  乗田理恵、藤田彩子、後藤愛那、二井勇人、内田隆史
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  仙台市、東北大学
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] c-mycに作用し構造変化するPin1-FRET法の構築2013
- Author(s)
  岡部恵美子、日高將文、内田隆史
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  仙台市、東北大学
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] リン酸化Tauの微小管重合促進能を回復させる因子Pin1およびhGas72013
- Author(s)
  清水泰希、小坂啓太、林悠太、岡部恵美子、藤田彩子、後藤愛那、日高將文、内田隆史
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  仙台市、東北大学
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] Establishment of adipose-derived mesenchymal stem cell lines from a p53-knockout mouse2012
- Author(s)
  Komine A, Abe M, Saeki T, Terakawa T, Uchida C and Uchida T
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡市、マリンメッセ
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] Visualization of Pin1-phosphopeptide association with FRET-based indicators2012
- Author(s)
  岡部恵美子、日高将文、内田隆史
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡市、マリンメッセ
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] Gas7bと細胞骨格タンパク質actin、tubulinとの関連2012
- Author(s)
  後藤　愛那、広瀬　恵子、内田　隆史
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡市、マリンメッセ
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] 微小管重合制御因子の探索2010
- Author(s)
  藤田彩子・甲賀友恵・後藤愛那・坂本渉・寺川貴裕・内田隆史
- Organizer
  日本農芸化学会大会
- Place of Presentation
  東京
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] Pinl阻害剤の探索系の確立2010
- Author(s)
  吉澤いぶき・林宜瑾・坂場義正・多田羅洋太・須田義人・纐纈守・豊原治彦・塩見和朗・大村智・山下まり・森正・内田隆史
- Organizer
  日本農芸化学会大会
- Place of Presentation
  東京
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] hGas7b Enhances Microtubule Polymerization but Blocks Kinesin Movement on Microtubule2010
- Author(s)
  Masafumi Hidaka, Tomoe Koga, Aina Goto, Hideo Higuchi, Takafumi Uchida
- Organizer
  4th Mechanobiology Workshop : Actin, The Cytoskeleton and the Nucleus
- Place of Presentation
  シンガポール
- Year and Date
  2010-11-10
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] 微小管重合を調節するタンパク質および化学物質の探索2009
- Author(s)
  坂本渉・林宜瑾・甲賀友恵・纐纈守・奥田徹・内田隆史
- Organizer
  日本農芸化学会大会
- Place of Presentation
  福岡
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] 微小管重合調節因子Gas7と微小管の直接結合の可能性2009
- Author(s)
  甲賀友恵、坂本渉、秋山弘匡、Nguyen Anh Hoa,樋口秀男、内田隆史
- Organizer
  生体運動研究合同班会議2009 in TOKYO
- Place of Presentation
  東京大学駒場
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] Establishment of High-Throughput Screening for Prolyl Isomerasese Inhibitors with Real-time Fluorescence Monitoring System2009
- Author(s)
  TADASHI MORI, SEIMA ITAMI, MARI TAKAMIYA, TSUTOMU KAMIYAMA, TAKAFUMI UCHIDA
- Organizer
  16th SBS annual meeting
- Place of Presentation
  フェニックス、米国
- Year and Date
  2009-04-11
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] 細胞増殖抑制タンパク質Gas7による微小管重合制御2009
- Author(s)
  後藤愛那、甲賀友恵、坂本渉、秋山弘匡、内田隆史
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] Tally Naveh-Many The peptidyl-prolyl isomerase Pin1 determines parathyroid hormone mRNA stability in vitro, in Pin1 knockout mice and in rats with experimental kidney disease2008
- Author(s)
  Morris Nechama, Hirotada Akiyama, Takafumi Uchida, Justin Silver
- Organizer
  RNA TURNOVER
- Place of Presentation
  Asheville, USA
- Year and Date
  2008-10-19
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] アルツハイマー病患脳で減少しているGas7はリン酸化Tau に結合し微小管シート構造を安定化させる2008
- Author(s)
  秋山弘匡、伊藤知彦、辛龍雲、東誉人、後藤愛那、原田彰宏、内田隆史
- Organizer
  BMB2008(第31回日本分子生物学会年会第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] 天然物由来のリン酸化蛋白質特異的プロリン異性化酵素機能調節剤の探索2008
- Author(s)
  内田隆史
- Organizer
  2008年度大会日本農芸化学会産学官学術交流委員会フォーラム・企画賞中間報告
- Place of Presentation
  名古屋名城大学
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] Harmful increase of astrocytic Ca2+ trigger reactive oxygen species production2008
- Author(s)
  Morito R, Miyazaki K, Kadji HG, Uchida T, Kawashima R, Riera JJ
- Organizer
  Gordon Research Conferences on Brain Energy Metabolism & Blood Flow
- Place of Presentation
  Andover, USA
- Year and Date
  2008-08-08
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] 天然物由来のリン酸化蛋白質特異的プロリン異性化酵素機能調節剤の探索2008
- Author(s)
  内田隆史
- Organizer
  日本農芸化学会(産学官学術交流委員会フォーラム)
- Place of Presentation
  名古屋
- Year and Date
  2008-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Presentation] Harmful increase of astrocytic Ca2+ trigger reactive oxygen species production2008
- Author(s)
  Rieko Morito, Kenichi Miyazaki, Herve Germain Enjieu Kadji, Takafumi Uchida, Ryuta Kawashima, Jorge Riera
- Organizer
  The 3rd International Society for Neurochemistry Special Neurochemistry Conference
- Place of Presentation
  Chaina/Beijin
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] Novel microtubule regulatory proteins, Pin1 and Gas72008
- Author(s)
  Takafumi Uchida
- Organizer
  12th Akabori Conference
- Place of Presentation
  Kyoto
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] Tally Naveh-Many The prolyl isomerase Pin1 determines PTH expression in vitro, in Pin1 knockout mice and in secondary hyperparathyroidism2008
- Author(s)
  Morris Nechama, Takafumi Uchida, Justin Silver
- Organizer
  American Society of Nephorology
- Place of Presentation
  Philaderphia, USA
- Year and Date
  2008-11-20
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] Screening for natural compounds that regulate Pin12008
- Author(s)
  Takafumi Uchida
- Organizer
  Annual Meeting of Japan Society for Bioscience Biotechnology & Agrochemistry Special report
- Place of Presentation
  Nagoya
- Year and Date
  2008-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Presentation] プロリン異性但酵素Pinlの分子生物学-ライフサィエンスの応用を目指して-2008
- Author(s)
  内田隆史
- Organizer
  第5回東北大学バイオサイエンスシンポジウム
- Place of Presentation
  仙台国際センター
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-20228006
[Presentation] プロリン異性化酵素Pin1の分子生物学-ライフサイエンスの応用を目指して-2008
- Author(s)
  内田隆史
- Organizer
  第5回東北大学ライフサイエンスセミナーシンポジウム
- Place of Presentation
  Sendai
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] hGas7b that controls microtubule dynamics is degraded in Alzheimer's brain2008
- Author(s)
  Hirotada Akiyama, Tomohiko J. Itoh, Takahito Higashi, Ryong-Woon Shin, Keiko Hirose, Akihiro Harada, Chiyoko Uchida and Takafumi Uchida
- Organizer
  2008nano学会
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] プロリン異性化酵素Pin1の分子生物学-ライフサイエンスの応用を目指して-2008
- Author(s)
  内田隆史
- Organizer
  東北大学ライフサイエンスセミナーシンポジウム
- Place of Presentation
  仙台国際センター
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] 暗視野顕微鏡による微小管重合調節剤の探索2008
- Author(s)
  坂本渉・奥田徹・山下まり・山口高弘・渡邊康一・内田隆史
- Organizer
  第5回東北大学バイオサイエンスシンポジウム(ポスターセッション)
- Place of Presentation
  仙台
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] 前頭側頭葉認知症(FTDP-17)変異型タウの脱リン酸化2008
- Author(s)
  浅田明子、四本健介、斎藤太郎、笈川貴之、石黒幸一、内田隆史、長谷川成人、久永真市
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] リン酸化タンパク質の構造と機能を変化させるタンパク質。生体システムの制御の基盤となる蛋白質の構造変化2007
- Author(s)
  内田隆史
- Organizer
  第7回日本蛋白質学会(ワークショップ)
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] Overview of"Bio-nanosystems in Cells"and Novel Regulatory Molecules for Phosphorylated Protein2007
- Author(s)
  内田隆史
- Organizer
  International symposium on Bio-nanosystem(Workshio; Bio-nanosystem in Cells)Sep, 2006, (Matsushima)
- Place of Presentation
  仙台
- Year and Date
  2007-09-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Presentation] リン酸化タンパク質の構造と機能を変化させるタンパク質。生体システムの制御の基盤となる蛋白質の構造変化2007
- Author(s)
  内田隆史
- Organizer
  第7回日本蛋白質学会ワークショップ
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Presentation] リン酸化タンパク質の構造と機能を変化させるタンパク質。生体システムの制御の基盤となる蛋白質の構造変化2007
- Author(s)
  内田隆史
- Organizer
  第7回日本蛋白質学会(ワークショップ)
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-16380225
[Presentation] Novel Protein changing the structure and function of phosphorylated proteins2007
- Author(s)
  Takafumi Uchida
- Organizer
  Annual Meeting of Protein Society Work shop
- Place of Presentation
  Sendai
- Year and Date
  2007-05-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Presentation] 脳特異的に発現するGas7はリン酸化Tauに結合し微小管シート構造を安定化させた2007
- Author(s)
  東誉人、辛龍雲、原田彰宏、秋山弘匡、内田隆史
- Organizer
  第30回日本分子生物学会(ワークショップ)
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-16083202
[Presentation] Overview of "Bio-nanosystems in Cells" and Novel Regulatory Molecules for Phosphorylated Protein2006
- Author(s)
  Takafumi Uchida
- Organizer
  International symposium on Bio-nanosystem(Workshop;Bio-nanosystem in Cells)
- Place of Presentation
  Matsushima
- Year and Date
  2006-09-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Presentation] Gas7, A Novel Microtubule Polymerization Accelerator Stabillizes Sheet Structure of The Polymerization Intermediate2006
- Author(s)
  内田隆史
- Organizer
  Ameican Cell Biology Meeting
- Place of Presentation
  SanDiego(USA)
- Year and Date
  2006-12-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Presentation] リン酸化タンパク質の機能調節に関わるプロリン異性化酵素Pinl2006
- Author(s)
  内田隆史
- Organizer
  ポリアミン研究会特別講演
- Place of Presentation
  仙台
- Year and Date
  2006-01-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Presentation] Pinl, a regulatory molecule of phosphorylated proteins2006
- Author(s)
  Takafumi Uchida
- Organizer
  Japan Polyamine Meeting Special lecture
- Place of Presentation
  Sendai
- Year and Date
  2006-01-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Presentation] Gas7, A Novel Microtubule Polymerization Accelerator Stabillizes Sheer Structure of The Polymerization Intermediate2006
- Author(s)
  Takafumi Uchida
- Organizer
  Ameican Cell Biology Meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2006-12-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Presentation] Role of phosphorylated protein regulator, Pinl on cancer and Alzheimer''s disesease2004
- Author(s)
  Takafumi Uchida
- Organizer
  Annual Meeting of Japan Society for Biophysics
- Place of Presentation
  Kyoto
- Year and Date
  2004-12-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Presentation] 癌・アルツハイマー病とリン酸化調節因子Pihlの役割2004
- Author(s)
  内田隆史
- Organizer
  第42回日本生物物理学会(シンポジウム)
- Place of Presentation
  京都
- Year and Date
  2004-12-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380225
[Presentation] The nitrate-sensing NasST system regulates nitrous oxide reductase in Bradyrhizobium japonicum
- Author(s)
  Cristina Sanchez, Manabu Itakura, Takashi Okubo, Takashi Matsumoto, Hirofumi Yoshikawa, Aina Gotoh, Masafumi Hidaka, Takafumi Uchida, Kiwamu Minamisawa
- Organizer
  15th International Symposium on Microbial Ecology
- Place of Presentation
  Coex Comvention Center (Seoul, Korea)
- Year and Date
  2014-08-24 – 2014-08-29
- Data Source
  KAKENHI-PROJECT-26252065

1. UCHIDA Chiyoko (80312776)

# of Collaborated Projects: 6 results

# of Collaborated Products: 215 results
2. TAKAHASHI Katuhiko (80307066)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. KAWATANI Makoto (50391925)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KIYOTA Hiromasa (30234397)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. USUI Takeo (60281648)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. FUKUMOTO Manabu (60156809)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. HIGUCHI Hideo (90165093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SHINGYOJI Chikako (80125997)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HIROSE Kenzo (00292730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUTOH Kazuo (20111453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HARADA Masahiko (70218642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. ITOU Tomohiko (30183742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. YAMASHITA Mari (50192430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. HIROSE Keiko (90357872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. OKUDA Toru (40328026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. Minamisawa Kiwamu (70167667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. FUJIMORI Fumihiro (50318226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. RYONG-WOON Shin (40271910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
19. Amano Hitoshi (90212571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. Takahashi Noriko (50277696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
21. IZUMI Minoru (90379719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. SAKAI Satoshi (30282362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 日高將文 (00584848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 二井勇人 (90447459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
25. 佐藤修正 (70370921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 竹林勇二 (70321982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 八木淳二 (70182300)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 秋山弘匡 (40400254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
29. 今村博臣 (20422545)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 柳川徹 (10312852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
31. 正田純一 (90241827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
32. SHI Qinq-Wen

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 西森克彦

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. HARA Kenshiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. EITSUKA Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. ONO Hiraku

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 南沢究

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
38. 佐藤英明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 武川寛樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
40. 廣瀬恵子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
41. 日高将文

# of Collaborated Projects: 0 results

# of Collaborated Products: 14 results
42. 豊原治彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 豊原容子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 本橋ほづみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 蕨栄治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 神尾好是

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 金子淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

UCHIDA Takafumi 内田 隆史

Research Projects

Research Products

Co-Researchers

Role of Pin1 in the development of pulmonary hypertension and therapeutic application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Is inducion of osteoblasts proliferation useful to treat the osteporosis patients?

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of symbiotic evolution and N2O mitigation of soybean bradyrhizobia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Preparation for PTD-Pin1 and its appllication to stem cell differentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prevention, diagnosis and drug discovery of aging diseases using Pin1 related moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of agrochemical and pharmaceutical lead compounds based on the search and total synthesis of natural compounds with a unique structure and biological activity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Total synthesis and investigation of biologically active natural compounds with novel and complex structures and its application to the development of agricultural and pharmaceutical lead compounds

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Drug Discovery of Alzheimer Disease from Molecules- Regulating Microtubule PolymerizationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

プロリン異性化酵素を標的とした薬剤Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of Bio-nanosystems

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Integrated Mechanism Regulating Phosphorylation- Dependent Signal TransductionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the stress resistance functions of Prolyl Isomerase Pin1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

リン酸化蛋白質の構造を変化させる新規蛋白質の発見Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

UCHIDA Takafumi 内田隆史