YAMAMOTO Takaharu 山本隆晴

Researcher Number	80312346
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2016: 北海道大学, 遺伝子病制御研究所, 助教 2007 – 2011: 北海道大学, 遺伝子病制御研究所, 助教 2006: 遺伝子病制御研究所, 助手 2000 – 2006: 北海道大学, 遺伝子病制御研究所, 助手
Review Section/Research Field	Principal Investigator General medical chemistry / Biological Sciences / Functional biochemistry / Cell biology Except Principal Investigator Cell biology / Science and Engineering / Biological Sciences
Keywords	Principal Investigator アクチン細胞骨格 / WASP-interacting protein / 出芽酵母 / MTI1 / 細胞運動 / SH3ドメイン / I型ミオシン / ArfGAP / アレスチン / 脂質 … More / 遺伝学 / モデル生物 / フリッパーゼキナーゼ / 細胞内小胞輸送 / リン脂質フリッパーゼ / リン脂質非対称分布 / 生体膜 / Hip1 / WIP / WASP / Rho / Eps15 / HIP1 / F-アクチン / ミオシン / 低分子量G蛋白質 / PAK / フォルミン / セブチン / 細胞極性形成 / UCSドメイン / SHE4 / 蛋白質間相互作用 / two-hybrid / 合成致死 / MYO5 / unconventional ミオシン / unconventionalミオシン / 遺伝学的相互作用 / プロリンリッチドメイン / 蛋白質-蛋白質相互作用 … More Except Principal Investigator P-type ATPase / 細胞極性 / リン脂質トランスロケース / 酵母 / 細胞内小胞輸送 / 脂質の非対称性 / 細胞骨格 / 出芽酵母 / Phospholipid translocase / Lipid asymmetry / Yeast / Endocytosis / Intracellular vesicle transport / Cytoskeleton / Cell polarity / ゴルジ体 / アミノリン脂質トランスロケース / エンドサイトーシス / リン酸質トランスロケース / Cdc42 small GTPase / タンパク質リン酸化酵素 / 細胞膜 / 光ピンセット / ナノバイオ / 生物・生体工学 / 計測工学 / 応用光学・量子光工学 / 細胞生物学 / トランスロケーション / リン脂質 / 脂質二重層 / メンブレントラフィック / 温度感受性変異 / アクチン / タイプIミオシン Less

リン脂質フリッパーゼが誘導する輸送小胞形成の試験管内再構成Principal Investigator
- Principal Investigator
  
  山本隆晴
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Hokkaido University
Role of novel kinases that regulate the function of phospholipid flippasesPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Takaharu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Hokkaido University
Regulation of membrane trafficking and cell polarity by changes in phospholipid asymmetry
- Principal Investigator
  
  YANAKA Kazuma
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Hokkaido University
フォトンフォース計測技術を用いた細胞系ダイナミック分析法の開発
- Principal Investigator
  
  笹木敬司
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
膜リン脂質の非対称性がメンブレントラフィックに果たす役割
- Principal Investigator
  
  鎌田このみ
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Roles for phospholipid asymmetry in cell polarity
- Principal Investigator
  
  TANAKA Kazuma
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Hokkaido University
癌細胞の浸潤・転移に関与するアクチン細胞骨格制御蛋白質の機能解析Principal Investigator
- Principal Investigator
  
  山本隆晴
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Hokkaido University
アクチン細胞骨格再編成に関与する蛋白質間相互作用の役割Principal Investigator
- Principal Investigator
  
  山本隆晴
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
出芽酵母ミオシン分子の機能制御機構の解析
- Principal Investigator
  
  KAMADA Konomi
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Hokkaido University
アクチン細胞骨格系を制御するシグナル伝達蛋白質群の分子間相互作用機構Principal Investigator
- Principal Investigator
  
  山本隆晴
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
癌細胞の浸潤・転移に関与するミオシンモーター分子の探索Principal Investigator
- Principal Investigator
  
  山本隆晴
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Hokkaido University

All 2012 2011 2010 2008 2007 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] Mutations in N-terminal Flanking Region of Blue Light-sensing Light-Oxygen and Voltage 2 (LOV2) Domain Disrupt Its Repressive Activity on Kinase Domain in the Chlamydomonas Phototropin2012
- Author(s)
  Yusuke Aihara, Takaharu Yamamoto, Koji Okajima, Kazuhiko Yamamoto, Tomomi Suzuki, Satoru Tokutomi, Kazuma Tanaka, Akira Nagatani
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 287 Issue: 13 Pages: 9901-9909
- DOI
  10.1074/jbc.m111.324723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J01094, KAKENHI-PROJECT-21370020, KAKENHI-PROJECT-21370085, KAKENHI-PROJECT-21570192, KAKENHI-ORGANIZER-22120001, KAKENHI-PLANNED-22120002, KAKENHI-PLANNED-22120005, KAKENHI-PROJECT-23657105, KAKENHI-PROJECT-23770040
[Journal Article] Mutations in the N-terminal flanking region of the blue-light sensing domain LOV2 disrupt its repressive activity on the kinase domain in the Chlamydomonas phototropin2012
- Author(s)
  Aihara Y, Yamamoto T, Okajima K, Yamamoto K, Suzuki T, Tokutomi S, Tanaka K, Nagatani A
- Journal Title
  
  J Biol Chem.
  
  Volume: 287(13) Pages: 9901-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570192
[Journal Article] Functions of phospholipid flippases.2011
- Author(s)
  Tanaka K, Fujimura-Kamada K, Yamamoto T.
- Journal Title
  
  J Biochem.
  
  Volume: 149 Pages: 131-143
- NAID
  10030583216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570192
[Journal Article] Konomi Fujimura-Kamada and Takaharu YamamotoFunctions of phospholipid flippases2011
- Author(s)
  Kazuma Tanaka
- Journal Title
  
  J Biochem
  
  Volume: 149 Issue: 2 Pages: 131-143
- DOI
  10.1093/jb/mvq140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370085, KAKENHI-PROJECT-21570192
[Journal Article] Initial polarized bud growth byendocytic recycling in the absence of actin cable-dependent vesicle transport in yeast2010
- Author(s)
  Yamamoto T, Mochida J, Kadota J, Takeda M, Bi E, and Tanaka K
- Journal Title
  
  Mol Biol Cell
  
  Volume: 21 Issue: 7 Pages: 1237-1252
- DOI
  10.1091/mbc.e09-05-0412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370085, KAKENHI-PROJECT-21570192
[Journal Article] Protein kinases Fpk1p and Fpk2p are novel regulators of phospholipid asymmetry2008
- Author(s)
  Nakano K, Yamamoto T, Kishimoto T, Noji T, Tanaka K.
- Journal Title
  
  Mol. Biol. Cell 19
  
  Pages: 1783-1797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370074
[Journal Article] Endocytic recycling in yeast is regulated by putative phospholipid translocases and the Ypt31p/32p-Rcy1p pathway2007
- Author(s)
  Furuta N, Fujimura-Kamada K, Saito K, Yamamoto T, Tanaka K.
- Journal Title
  
  Mol. Biol. Cell 18
  
  Pages: 295-312
- NAID
  120000967896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370074
[Journal Article] Mutational analysis of the Lem3p-Dnf1p putative phospholipid-translocating P-type ATPase reveals novel regulatory roles for Lem3p and a carboxyl-terminal region of Dnf1p independent of the phospholipid-translocating activity of Dnf1p in yeast2006
- Author(s)
  Noji T, Yamamoto T, Saito K, Fujimura-Kamada K, Kondo S, Tanaka K.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 344
  
  Pages: 323-331
- NAID
  120000955300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370074
[Journal Article] The functional relationship between the Cdc50p-Drs2p putative aminophospholipid translocase and the Arf GAP Gcs1p in vesicle formation in the retrieval pathway from yeast early endosomes to the TGN2006
- Author(s)
  Sakane H, Yamamoto T, Tanaka K.
- Journal Title
  
  Cell Struct. Funct. 31
  
  Pages: 87-108
- NAID
  130004137511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370074
[Journal Article] Identification of novel mutations in ACT1 and SLA2 that suppress the actin cable-overproducing phenotype caused by overexpression of a dominant active form of Bni1p in Saccharomyces cerevisiae2006
- Author(s)
  Yoshiuchi S, Yamamoto T, Sakane H, Kadota J, Mochida J, Asaka M, Tanaka K.
- Journal Title
  
  Genetics 173
  
  Pages: 527-539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370074
[Journal Article] Defects in Structural Integrity of Ergosterol and the Cdc50p-Drs2p Phospholipid Translocase Cause Accumulation of Endocytic Membranes, onto Which Actin Patches Are Assembled in Yeast2005
- Author(s)
  Kishimoto, T., Yamamoto, T., Tanaka, K.
- Journal Title
  
  Mol.Biol.Cell 16
  
  Pages: 5592-5609
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370081
[Journal Article] Septin ring assembly requires concentrated action of polarisome components, a PAK kinase Cla4p, and the actin cytoskeleton in Saccharomyces cerevisiae2004
- Author(s)
  Kadota, J., Yamamoto, T., Yoshiuchi, S., Bi, E., Tanaka, K.
- Journal Title
  
  Mol.Biol.Cell 15
  
  Pages: 5329-5345
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370081
[Journal Article] Initial Polarized Bud Growth by Endocytic Recycling in the Absence of Actin Cable-dependent Vesicle Transport in Yeast
- Author(s)
  Yamamoto T., et al
- Journal Title
  
  Molecular Biology of the Cell (印刷中)
- NAID
  120002087040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570192
[Presentation] The role of phospholipid asymmetry in the localization of tryptophan permease Tat2p2011
- Author(s)
  鉢呂健, 山本隆晴, 田中一馬
- Organizer
  第63回細胞生物学会大会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-21570192
[Presentation] 細胞内小胞輸送におけるリン脂質フリッパーゼの役割2011
- Author(s)
  山本隆晴、鎌田このみ、花松久寿、Zahra Zendehboodi、武田美代子、田中一馬
- Organizer
  第48回日本生化学会北海道支部例会
- Place of Presentation
  札幌医科大学(札幌市)
- Year and Date
  2011-08-05
- Data Source
  KAKENHI-PROJECT-21570192
[Presentation] Functions of the non-catalytic region of Gcslp in the phospholipid flippase-regulatingmembrane trafficking pathway2011
- Author(s)
  Zahra Zendehboodi, Takaharu Yamamoto, Kazuma Tanaka
- Organizer
  第63回細胞生物学会大会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-21570192
[Presentation] 膜輸送におけるリン脂質フリッパーゼの役割Roles of phospholipid flippases in membrane trafficking2011
- Author(s)
  山本隆晴, 鎌田このみ, 田中一馬
- Organizer
  第63回細胞生物学会大会
- Place of Presentation
  北海道大学(札幌市)(招待講演)
- Year and Date
  2011-06-28
- Data Source
  KAKENHI-PROJECT-21570192
[Presentation] 膜輸送におけるリン脂質フリッパーゼの役割2011
- Author(s)
  山本隆晴
- Organizer
  第63回細胞生物学会大会
- Place of Presentation
  北海道大学
- Year and Date
  2011-06-28
- Data Source
  KAKENHI-PROJECT-21570192
[Presentation] The Role of Phospholipid Asymmetry in Vesicle Transport in the Early Endosome-to-TGN Retrieval Pathway2011
- Author(s)
  武田美代子, 山本隆晴, 田中一馬
- Organizer
  第63回細胞生物学会大会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-21570192
[Presentation] 細胞内小胞輸送におけるリン脂質フリッパーゼの役割2011
- Author(s)
  山本隆晴
- Organizer
  第48回日本生化学会北海道支部例会
- Place of Presentation
  札幌医科大学
- Year and Date
  2011-08-05
- Data Source
  KAKENHI-PROJECT-21570192
[Presentation] Roles of phospholipid flippases and their related ArfGAP for protein trafficking2010
- Author(s)
  Takaharu Yamamoto, Takeru Hachiro, Zahra Zendehboodi, Kazuma Tanaka
- Organizer
  第27回内藤コンファレンス
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ(札幌市) 招待講演
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-21570192
[Presentation] Roles of phospholipid flippases and their related ArfGAP for protein trafficking2010
- Author(s)
  山本隆晴
- Organizer
  第27回内藤コンファレンス
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-21570192
[Presentation] Regulation and functional significance of phospholipid asymmetry2010
- Author(s)
  田中一馬、鎌田このみ、山本隆晴
- Organizer
  第27回内藤コンファレンス
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ(札幌市) 招待講演
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-21570192

1. YANAKA Kazuma (60188290)

# of Collaborated Projects: 7 results

# of Collaborated Products: 18 results
2. KAMADA Konomi (80312354)

# of Collaborated Projects: 7 results

# of Collaborated Products: 6 results
3. NAGATANI Akira (40183082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 笹木敬司 (00183822)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 久保田高明 (60399954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMAMOTO Takaharu 山本 隆晴

Research Projects

Research Products

Co-Researchers

リン脂質フリッパーゼが誘導する輸送小胞形成の試験管内再構成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of novel kinases that regulate the function of phospholipid flippasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of membrane trafficking and cell polarity by changes in phospholipid asymmetry

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

フォトンフォース計測技術を用いた細胞系ダイナミック分析法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

膜リン脂質の非対称性がメンブレントラフィックに果たす役割

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Roles for phospholipid asymmetry in cell polarity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

癌細胞の浸潤・転移に関与するアクチン細胞骨格制御蛋白質の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アクチン細胞骨格再編成に関与する蛋白質間相互作用の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

出芽酵母ミオシン分子の機能制御機構の解析

Principal Investigator

Project Period (FY)

Research Category

Research Institution

アクチン細胞骨格系を制御するシグナル伝達蛋白質群の分子間相互作用機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

癌細胞の浸潤・転移に関与するミオシンモーター分子の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Mutations in N-terminal Flanking Region of Blue Light-sensing Light-Oxygen and Voltage 2 (LOV2) Domain Disrupt Its Repressive Activity on Kinase Domain in the Chlamydomonas Phototropin2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mutations in the N-terminal flanking region of the blue-light sensing domain LOV2 disrupt its repressive activity on the kinase domain in the Chlamydomonas phototropin2012

Author(s)

Journal Title

Data Source

[Journal Article] Functions of phospholipid flippases.2011

Author(s)

YAMAMOTO Takaharu 山本隆晴