KITAMURA Hiroshi 北村浩

… Alternative Names

北村浩キタムラヒロシ

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Researcher Number	80312403
Other IDs
External Links
Affiliation (Current)	2025: 東北大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2025: 酪農学園大学, 獣医学群, 教授 2014 – 2023: 酪農学園大学, 獣医学群, 教授 2014: 酪農学園大学, 獣医学部, 教授 2013: 名古屋私立大学, 医学系研究科, 准教授 2012 – 2013: 名古屋市立大学, 医学(系)研究科(研究院), 准教授 … More 2010 – 2011: 名古屋市立大学, 大学院・医学研究科, 准教授 2009: The Institute of Physical and Chemical Research, 免疫ゲノミクス研究グループ, 上級研究員 2007: The Institute of Physical and Chemical Research, 免疫ゲノミクス研究グループ, 上級研究員 2004 – 2006: 独立行政法人理化学研究所, 免疫ゲノミクス研究グループ, 上級研究員 2003: 独立行政法人理化学研究所, 免疫ゲノミクス研究チーム, 研究員 2002: 理化学研究所, 免疫ゲノムクス研究チーム, 研究員 2000 – 2001: 北海道大学, 大学院・獣医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 42040:Laboratory animal science-related / Basic veterinary science/Basic zootechnical science / Laboratory animal science / Laboratory animal science / Pathological medical chemistry / Basic veterinary science/Basic zootechnical science Except Principal Investigator Basic Section 42020:Veterinary medical science-related / Basic Section 48040:Medical biochemistry-related / Laboratory animal science / Laboratory animal science / Applied veterinary science
Keywords	Principal Investigator マクロファージ / 炎症 / 骨格筋 / USP / ユビキチン / マイクロアレイ / USP2 / 遺伝子改変マウス / 筋芽細胞 / 視床下部 … More / エネルギー代謝 / 2型糖尿病 / ２型糖尿病 / 遺伝子組換えマウス / 糖代謝 / 遺伝子発現 / ノックアウトマウス / トランスクリプトーム / ミトコンドリア / リポ多糖体 / Bリンパ球 / MAIL / 臓器間クロストーク / 筋萎縮 / NAFLD / メタボリックシンドローム / 筋委縮 / 酸化ストレス / 糖尿尿 / NAFL / NASH / インスリン抵抗性 / 筋損傷 / 組織選択的ノックアウトマウス / 交感神経 / 運動精子 / インスリン / GM-CSF / 間脳視床下部 / インスリン感受性 / 神経 / 精巣 / 筋細胞 / 酸化的リン酸化 / サイトカイン / ob/obマウス / 肥満 / 遺伝子組み換えマウス / 慢性炎症 / 核内タンパク質 / 脂肪組織 / トランスジェニックマウス / 糖尿病 / がん幹細胞 / 網羅的遺伝子発現解析 / 疾患関連分子 / ミエロイド / 急性骨髄性白血病 / エクソンアレイ / スプライシング / 白血病幹細胞 / 骨髄性白血病 / ゲノム / 呼吸鎖 / 転写後調節 / JNK / ポリソーム / 翻訳調節 / TLR4 / cDNAアレイ / NF-κB / アトピー性皮膚炎 / NFκB / IκB / 新規遺伝子 / ストレス / IkB / 脳 / LPS / SSeCKS … More Except Principal Investigator 遺伝子組換えマウス / 間葉系前駆細胞 / マイトファジー / 異常胸肉 / ブロイラー / 免疫細胞 / DR6 / マクロファージ / 腫瘍 / TNFRSF21 / 卵管特異的糖タンパク質（OGP） / がん化の分子機構 / ゲノム編集 / 卵巣癌モデルマウス / 実験動物学 / 脂肪組織 / 血糖調節 / スフィンゴ糖脂質 / 疾患モデル / がん幹細胞 Less

骨格筋のユビキチンプロテアーゼに注目した糖尿病サルコペニアモデルの構築と病態解析Principal Investigator
- Principal Investigator
  
  北村浩
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Rakuno Gakuen University
生理的マイトファジーに着眼したブロイラーの異常胸肉の病態解明と抑制方法の開発
- Principal Investigator
  
  渡邉敬文
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Rakuno Gakuen University
Evaluation of roles of ubiquitin-specific proteases in NAFLD/NASH pathogenesis using cell-specific gene-engineered mouse modelsPrincipal Investigator
- Principal Investigator
  
  北村浩
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Rakuno Gakuen University
Functional analysis of death receptor 6 in anti-tumor immunity
- Principal Investigator
  
  Fujikura Daisuke
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Kitasato University
Evaluation of physiologocal roles of USP2 in energy metabolism by using cell-specific knockout modelsPrincipal Investigator
- Principal Investigator
  
  Kitamura Hiroshi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Rakuno Gakuen University
The elucidation of molecular mechanism of Epithelial ovarian cancer (EOC) model mouse
- Principal Investigator
  
  MIYOSHI ICHIRO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tohoku University
Roles of a novel key regulatory molecule, USP2, in energy homeostasisPrincipal Investigator
- Principal Investigator
  
  Hiroshi Kitamura
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Rakuno Gakuen University
Modulatory effects of macrophage M-mod/USP2 on type2 diabetesPrincipal Investigator
- Principal Investigator
  
  KITAMURA Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Rakuno Gakuen University
  Nagoya City University
Development of animal model for the blood sugar regulation by glycosphingolipids and study on the molecular pathogenesis of inflammation in adipose tissue
- Principal Investigator
  
  MIYOSHI ICHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Nagoya City University
Development of a method for isolating canine cancer initiating cells and a new cancer therapy based on their gene expression analyses
- Principal Investigator
  
  SHIMAMOTO Yoshinori
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied veterinary science
- Research Institution
  Kitasato University
Comprehensive analysis of splicing variants characteristic of acute myelogenous leukemia stem cellsPrincipal Investigator
- Principal Investigator
  
  KITAMURA Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagoya City University
  The Institute of Physical and Chemical Research
マクロファージのLPS応答における翻訳調整の役割と分子メカニズムの網羅的解析Principal Investigator
- Principal Investigator
  
  北村浩
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  The Institute of Physical and Chemical Research
新しいIκBタンパク質MAILのLPS炎症反応における役割および作用機序の解明Principal Investigator
- Principal Investigator
  
  北村浩
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  The Institute of Physical and Chemical Research
ストレスに応答する脳内新規遺伝子群の免疫修飾における役割の解析Principal Investigator
- Principal Investigator
  
  北村浩
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Hokkaido University

[Book] ゲノム編集食品～農林水産分野への応用と持続的社会の実現～第2編4章12021
- Author(s)
  橋本茉由子、北村　浩
- Total Pages
  7
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860437169
- Data Source
  KAKENHI-PROJECT-18K06035
[Book] ゲノム編集食品~農林水産分野への応用問持続的社会の実現～　第2編4章12021
- Author(s)
  橋本茉由子、北村　浩
- Total Pages
  7
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860437169
- Data Source
  KAKENHI-PROJECT-21K06001
[Journal Article] Flow cytometric detection of CD11b+ Gr-1+ cells in nontumor-bearing mice: A propolis-elicited model2024
- Author(s)
  Kitamura Hiroshi
- Journal Title
  
  Methods in Cell Biology
  
  Volume: 184 Pages: 17-32
- DOI
  10.1016/bs.mcb.2023.05.010
- ISBN
  9780443218071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06001
[Journal Article] Ubiquitin-Specific Proteases (USPs) and Metabolic Disorders2023
- Author(s)
  Kitamura Hiroshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 4 Pages: 3219-3219
- DOI
  10.3390/ijms24043219
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06001
[Journal Article] Association of lithocholic acid with skeletal muscle hypertrophy through TGR5-IGF-1 and skeletal muscle mass in cultured mouse myotubes, chronic liver disease rats and humans2022
- Author(s)
  Tamai Yasuyuki、Eguchi Akiko、Shigefuku Ryuta、Kitamura Hiroshi、Tempaku Mina、Sugimoto Ryosuke、Kobayashi Yoshinao、Iwasa Motoh、Takei Yoshiyuki、Nakagawa Hayato
- Journal Title
  
  eLife
  
  Volume: 11
- DOI
  10.7554/elife.80638
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06001, KAKENHI-PROJECT-21H02892
[Journal Article] Application of the colorimetric loop-mediated isothermal amplification (LAMP) technique for genotyping Cre-driver mice2022
- Author(s)
 FUJIMOTO Masaki、KITAMURA Hiroshi
- Journal Title
 
 Journal of Veterinary Medical Science
 
 Volume: 84 Issue: 4 Pages: 507-510
- DOI
 10.1292/jvms.21-0658
- NAID
 130008164660
- ISSN
 0916-7250, 1347-7439
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-18K06035, KAKENHI-PROJECT-21K06001
[Journal Article] USP2 in the ventromedial hypothalamus modifies blood glucose levels by controlling sympathetic nervous activation2022
- Author(s)
  Hashimoto Mayuko、Fujimoto Masaki、Konno Kohtarou、Lee Ming Liang、Yamada Yui、Yamashita Koya、Toda Chitoku、Tomura Michio、Watanabe Masahiko、Inanami Osamu、Kitamura Hiroshi
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: - Issue: 23 Pages: 4607-4618
- DOI
  10.1523/jneurosci.2504-21.2022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06035, KAKENHI-PROJECT-19J21213, KAKENHI-PROJECT-21K06001, KAKENHI-PROJECT-20KK0250, KAKENHI-PROJECT-20H00443, KAKENHI-PROJECT-23K21265
[Journal Article] USP2-Related Cellular Signaling and Consequent Pathophysiological Outcomes2021
- Author(s)
  Kitamura Hiroshi、Hashimoto Mayuko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 3 Pages: 1209-1209
- DOI
  10.3390/ijms22031209
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06035, KAKENHI-PROJECT-19J21213
[Journal Article] Introduction of a plasmid and a protein into bovine and swine cells by water-in-oil droplet electroporation2020
- Author(s)
  ISHINO Takeshi、KURITA Hirofumi、KIRISAWA Rikio、SHIMAMOTO Yoshinori、NUMANO Rika、KITAMURA Hiroshi
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 82 Issue: 1 Pages: 14-22
- DOI
  10.1292/jvms.19-0475
- NAID
  130007783759
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06002, KAKENHI-PROJECT-18K06035
[Journal Article] Lipin-2 degradation elicits a proinflammatory gene signature in macrophages2020
- Author(s)
  Watahiki Asami、Shimizu Kouhei、Hoshikawa Seira、Chiba Mitsuki、Kitamura Hiroshi、Egusa Hiroshi、Fukumoto Satoshi、Inuzuka Hiroyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 524 Issue: 2 Pages: 477-483
- DOI
  10.1016/j.bbrc.2020.01.119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03834, KAKENHI-PROJECT-19J11773, KAKENHI-PROJECT-18K19282, KAKENHI-PROJECT-18K19632, KAKENHI-PROJECT-18K06035
[Journal Article] Macrophage ubiquitin-specific protease 2 contributes to motility, hyperactivation, capacitation, and in vitro fertilization activity of mouse sperm2020
- Author(s)
  Hashimoto Mayuko、Kimura Shunsuke、Kanno Chihiro、Yanagawa Yojiro、Watanabe Takafumi、Okabe Jun、Takahashi Eiki、Nagano Masashi、Kitamura Hiroshi
- Journal Title
  
  Cellular and Molecular Life Sciences
  
  Volume: 78 Issue: 6 Pages: 2929-2948
- DOI
  10.1007/s00018-020-03683-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06035, KAKENHI-PROJECT-19K07239, KAKENHI-PROJECT-19J21213
[Journal Article] Effects of Propolis Extract and Propolis-Derived Compounds on Obesity and Diabetes: Knowledge from Cellular and Animal Models2019
- Author(s)
  Hiroshi Kitamura
- Journal Title
  
  Molecules
  
  Volume: 24 Issue: 23 Pages: 4394-4394
- DOI
  10.3390/molecules24234394
- NAID
  120006901081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06035
[Journal Article] Inhibition of ubiquitin‐specific protease 2 causes accumulation of reactive oxygen species, mitochondria dysfunction, and intracellular ATP decrement in C2C12 myoblasts2019
- Author(s)
  Hashimoto Mayuko、Saito Natsuko、Ohta Haru、Yamamoto Kumiko、Tashiro Asuka、Nakazawa Kosuke、Inanami Osamu、Kitamura Hiroshi
- Journal Title
  
  Physiological Reports
  
  Volume: 7 Issue: 14 Pages: 1-14
- DOI
  10.14814/phy2.14193
- NAID
  120006901082
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06035, KAKENHI-PROJECT-18K19254, KAKENHI-PROJECT-17H03920, KAKENHI-PROJECT-19J11509, KAKENHI-PROJECT-19J21213
[Journal Article] Macrophages Switch Their Phenotype by Regulating Maf Expression during Different Phases of Inflammation2018
- Author(s)
  Kikuchi Kenta、Iida Mayumi、Ikeda Naoki、Moriyama Shigetaka、Hamada Michito、Takahashi Satoru、Kitamura Hiroshi、Watanabe Takashi、Hasegawa Yoshinori、Hase Koji、Fukuhara Takeshi、Sato Hideyo、Kobayashi Eri H.、Suzuki Takafumi、Yamamoto Masayuki、Tanaka Masato、Asano Kenichi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 201 Issue: 2 Pages: 635-651
- DOI
  10.4049/jimmunol.1800040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07158, KAKENHI-PROJECT-17K08977, KAKENHI-PROJECT-18K06035, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-17H04052, KAKENHI-PROJECT-17H04068, KAKENHI-PROJECT-15K06805, KAKENHI-PROJECT-17K15590
[Journal Article] Generation and validation of novel anti-bovine CD163 monoclonal antibodies ABM-1A9 and ABM-2D62018
- Author(s)
  Yoshinori Shimamoto, Junko Nio-Kobayashi, Hiroshi Watarai, Masashi Nagano, Natsuko Saito, Eiki Takahashi, Hidetoshi Higuchi, Atsushi Kobayashi, Takashi Kimura, Hiroshi Kitamura
- Journal Title
  
  Veterinary Immunology and Immunopathology
  
  Volume: 198 Pages: 6-13
- DOI
  10.1016/j.vetimm.2018.02.004
- NAID
  120006798133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06805, KAKENHI-PROJECT-17K08502, KAKENHI-PROJECT-16K14591, KAKENHI-PROJECT-18K05963, KAKENHI-PROJECT-18K06035, KAKENHI-PROJECT-16H05022
[Journal Article] Establishment of protocol for preparation of gene-edited bovine ear-derived fibroblasts for somatic cell nuclear transplantation 2018
- Author(s)
 Takeshi Ishino, Mayuko Hashimoto, Misato Amagasa, Natsuko Saito, Osamu Dochi, Rikio Kirisawa, Hiroshi Kitamura
- Journal Title
 
 Biomed. Res.
 
 Volume: 39 Issue: 2 Pages: 95-104
- DOI
 10.2220/biomedres.39.95
- NAID
 130006708564
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-18K06035, KAKENHI-PROJECT-15K06805
[Journal Article] Brazilian propolis ethanol extract and its component kaempferol induce myeloid-derived suppressor cells from macrophages of mice in vivo and in vitro2018
- Author(s)
  Kitamura Hiroshi、Saito Natsuko、Fujimoto Junpei、Nakashima Ken-ichi、Fujikura Daisuke
- Journal Title
  
  BMC Complementary and Alternative Medicine
  
  Volume: 18 Issue: 1 Pages: 138-138
- DOI
  10.1186/s12906-018-2198-5
- NAID
  120006798131
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08570, KAKENHI-PROJECT-18K06035, KAKENHI-PROJECT-15K06805
[Journal Article] Macrophage ubiquitin-specific protease 2 modifies insulin sensitivity in obese mice.2017
- Author(s)
  Saito N, Kimura S, Miyamoto T, Fukushima S, Amagasa M, Shimamoto Y, Nishioka C, Okamoto S, Toda C, Washio K, Asano A, Miyoshi I, Takahashi E, Kitamura H.
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: 9 Pages: 322-329
- DOI
  10.1016/j.bbrep.2017.01.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07129, KAKENHI-PROJECT-17H05059, KAKENHI-PROJECT-15K06805, KAKENHI-PROJECT-16K08457
[Journal Article] Ubiquitin-Specific Protease 2 Modulates the Lipopolysaccharide-Elicited Expression of Proinflammatory Cytokines in Macrophage-like HL-60 Cells2017
- Author(s)
  Kitamura Hiroshi、Ishino Takeshi、Shimamoto Yoshinori、Okabe Jun、Miyamoto Tomomi、Takahashi Eiki、Miyoshi Ichiro
- Journal Title
  
  Mediators of Inflammation
  
  Volume: 2017 Pages: 1-15
- DOI
  10.1155/2017/6909415
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06805, KAKENHI-PROJECT-17K07129
[Journal Article] In situ hybridization study of CYP2D mRNA in the common marmoset brain2016
- Author(s)
 Shimamoto Y, Niimi K, Kitamura H, Tsubakishita S, Takahashi E
- Journal Title
 
 Exp. Anim.
 
 Volume: 65 Issue: 4 Pages: 465-471
- DOI
 10.1538/expanim.16-0045
- NAID
 130005277073
- ISSN
 0007-5124, 1341-1357, 1881-7122
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-15K06805
[Journal Article] Intestinal CD169+macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes2015
- Author(s)
  Kenichi Asano, Naomichi Takahashi, Mikiko Ushiki, Misa Monya, Fumiaki Aihara, Erika Kuboki,Shigetaka Moriyama,Mayumi Iida,Hiroshi Kitamura,　Chun-Hong Qiu,Takashi Watanabe, Masato Tanaka
- Journal Title
  
  Nat. Commun.
  
  Volume: 6 Issue: 1 Pages: 7802-7802
- DOI
  10.1038/ncomms8802
- NAID
  120006311913
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06805, KAKENHI-PROJECT-26460401, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-26293089
[Journal Article] Genetic background-dependent diversity in renal failure caused by the tensin2 gene deficiency in the mouse 2015
- Author(s)
 Hayato Sasaki, Kiyoma Marusugi, Junpei Kimura, Hiroshi Kitamura, Ken-ichi Nagasaki, Daisuke Torigoe, Takashi Agui, Nobuya Sasaki
- Journal Title
 
 Biomed. Res.
 
 Volume: 36 Issue: 5 Pages: 323-330
- DOI
 10.2220/biomedres.36.323
- NAID
 130005106627
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-15K06805, KAKENHI-PROJECT-13J00961, KAKENHI-PROJECT-25430083
[Journal Article] Brazilian propolis extract increases leptin expression in mouse adipocytes 2015
- Author(s)
 Kohei Washio, Yoshinori Shimamoto, Hiroshi Kitamura
- Journal Title
 
 Biomed. Res.
 
 Volume: 36 Issue: 5 Pages: 343-346
- DOI
 10.2220/biomedres.36.343
- NAID
 130005106629
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-15K06805
[Journal Article] Propolis ethanol extract stimulates cytokine and chemokine production through NF-kappaB activation in C2C12 myoblasts.2015
- Author(s)
  Kohei Washio, Mao Kobayashi, Natsuko Saito, Misato Amagasa, Hiroshi Kitamura
- Journal Title
  
  Evid-Based Comp. Alt. Med.
  
  Volume: 2015 Pages: 249751-249751
- DOI
  10.1155/2015/349751
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06805
[Journal Article] Colony-StimulatingFactor-1 Signaling Suppresses Renal Crystal Formation.2015
- Author(s)
  Taguchi Kazumi, Okada Atsushi, Kitamura Hiroshi, Yasui Takahiro, Naiki Taku, Hamamoto Shuzo, Ando Ryosuke, Mizuno Kentaro, Kawai Noriyasu, Tozawa Keiichi, Asano Kenichi, Tanaka Masato, Miyoshi Ichiro, Kohri Kenjiro
- Journal Title
  
  Journal of the American Society of Nephrology
  
  Volume: 25 Issue: 8 Pages: 1680-1697
- DOI
  10.1681/asn.2013060675
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23249074, KAKENHI-PROJECT-23390095, KAKENHI-PROJECT-24500494, KAKENHI-PROJECT-24500495, KAKENHI-PROJECT-24592434, KAKENHI-PROJECT-24659716, KAKENHI-PROJECT-24791663, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-26293089
[Journal Article] KLRG+ invariant natural killer T cells are long-lived effectors.2014
- Author(s)
  Shimizu K, Sato Y, Shinga J, Watanabe T, Endo T, Asakura M, Yamasaki S, Kawahara K, Kinjo Y, Kitamura H,Watarai H, Ishii Y, Tsuji M, Taniguchi M, Ohara O, Fujii S.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 111 Issue: 34 Pages: 12474-12479
- DOI
  10.1073/pnas.1406240111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23229005, KAKENHI-PROJECT-24500494
[Journal Article] Zinc transporter SLC39A10/ZIP10 facilitates antiapoptotic signaling during early B-cell development2014
- Author(s)
  Miyai T, Hojyo S, Ikawa T, Kawamura M, Irie T, Ogura H, Hijikata A, Bin BH, Yasuda T, Kitamura H, Nakayama M, Ohara O, Yoshida H, Koseki H, Mishima K, Fukada T
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: 111 Issue: 32 Pages: 11780-11785
- DOI
  10.1073/pnas.1323549111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500494, KAKENHI-PROJECT-24689042, KAKENHI-PUBLICLY-25118732, KAKENHI-PROJECT-25462874, KAKENHI-PROJECT-25462875, KAKENHI-PROJECT-26293229, KAKENHI-PROJECT-26462324, KAKENHI-PROJECT-26670472
[Journal Article] Ubiquitin-specific protease 2-69 in macrophages potentially modulates metainflammation.2013
- Author(s)
  Kitamura et al.
- Journal Title
  
  FASEB J.
  
  Volume: 27 Issue: 12 Pages: 4940-4953
- DOI
  10.1096/fj.13-233528
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117723, KAKENHI-PROJECT-24500494, KAKENHI-PROJECT-24500495, KAKENHI-PROJECT-25293114, KAKENHI-PROJECT-25460261, KAKENHI-PROJECT-25460401
[Journal Article] Selection of suitable reference genes for mRNA quantification studies using common marmoset tissues2013
- Author(s)
  Shimamoto Y, Kitamura H, Niimi K, Yoshikawa Y, Hoshi F, Ishizuka M, Takahashi E
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 40 Issue: 12 Pages: 6747-6755
- DOI
  10.1007/s11033-013-2791-0
- Data Source
  KAKENHI-PROJECT-24500494
[Journal Article] Beneficial effects of Brazilian propolis on type 2 diabetes in ob/ob mice: Possible involvement of immune cells in mesenteric adipose tissue2013
- Author(s)
  Kitamura H, Naoe Y, Kimura S, Miyamoto T, Okamoto S, Toda C, Shimamoto Y, Iwanaga T, Miyoshi I
- Journal Title
  
  Adipocyte
  
  Volume: 2 Issue: 4 Pages: 227-236
- DOI
  10.4161/adip.25608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500494, KAKENHI-PROJECT-24500495, KAKENHI-PROJECT-25460261, KAKENHI-PROJECT-25460401
[Journal Article] SP600125 Inhibits Cap-dependent Translation Independently of the c-Jun N-terminal Kinase Pathway2011
- Author(s)
  Masatoshi Ito, Hiroshi Kitamura, Chisato Kikuguchi, Koji Hase, Hiroshi Ohno, and Osamu Ohara
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 36 Issue: 1 Pages: 27-33
- DOI
  10.1247/csf.10025
- NAID
  130004137561
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790334
[Journal Article] Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes2011
- Author(s)
  Xiangzhi Li, Kyo-ichi Isono, Daisuke Yamada, Takaho A. Endo, Mitsuhiro Endoh, Jun Shinga, Yoko Mizutani-Koseki, Arie P. Otte, Miguel Casanova, Hiroshi Kitamura, Takehiko Kamijo, Jafar Sharif, Osamu Ohara, Tetsuro Toyada, Bradley E. Bernstein, Neil Brockdorff, and Haruhiko Koseki
- Journal Title
  
  Mol. Cell. Biol
  
  Volume: 31(2) Issue: 2 Pages: 351-364
- DOI
  10.1128/mcb.00259-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790334, KAKENHI-PUBLICLY-22116513
[Journal Article] The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells2011
- Author(s)
  Motomura, Y., et al
- Journal Title
  
  Nature Immunology
  
  Volume: 12 Issue: 5 Pages: 450-459
- DOI
  10.1038/ni.2020
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19059014, KAKENHI-PROJECT-21590547, KAKENHI-PROJECT-21790334, KAKENHI-PLANNED-22116010, KAKENHI-PROJECT-22390167, KAKENHI-PROJECT-23659243, KAKENHI-PROJECT-23390123
[Journal Article] CCR6hiCD11cint B cells promote M-cell differentiation in Peyer's patch2011
- Author(s)
  Ebisawa, M., et al
- Journal Title
  
  Int.Immunol.
  
  Volume: 23 Issue: 4 Pages: 261-269
- DOI
  10.1093/intimm/dxq478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390155, KAKENHI-PROJECT-21790334, KAKENHI-PROJECT-22689017
[Journal Article] A set of genes associated with the interferon-γ response of lung cancer patients undergoing α-galactosylceramide-pulsed dendritic cell therapy2010
- Author(s)
  Okita, K., Motohashi, S., Shinnakasu, R., Nagato, K., Yamasaki, K., Sato, Y., Kitamura, H., Hijikata, A., Yamashita, M., Shimizu, K., Fujii, S., Ohara, O., Taniguchi, M., Sakaida, I., Nakayama, T
- Journal Title
  
  Cancer Sci
  
  Volume: 101(11) Issue: 11 Pages: 2333-2340
- DOI
  10.1111/j.1349-7006.2010.01696.x
- NAID
  10027833301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591808, KAKENHI-PROJECT-21790334
[Journal Article] Characterization of multiple alternative forms of heterogeneous nuclear ribonucleoprotein K by phosphate-affinity electrophoresis2010
- Author(s)
  Yayoi Kimura, Kayoko Nagata, Nobutake Suzuki, Ryo Yokoyama, Yuko Yamanaka, Hiroshi Kitamura, Hisashi Hirano, Osamu Ohara
- Journal Title
  
  Proteomics
  
  Volume: 10(21) Issue: 21 Pages: 3884-3895
- DOI
  10.1002/pmic.201000349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790334
[Journal Article] The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut2010
- Author(s)
  Keiichiro Suzuki, Mikako Maruya, Shimpei Kawamoto, Katarzyna Sitnik, Hiroshi Kitamura, William W. Agace, Sidnia Fagarasan
- Journal Title
  
  Immunity
  
  Volume: 33(1) Issue: 1 Pages: 71-83
- DOI
  10.1016/j.immuni.2010.07.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790334
[Journal Article]2010
- Author(s)
  Yoriko Saito*, Hiroshi Kitamura*, Atsushi Hijikata, Mariko Tomizawa-Murasawa, Satoshi Tanaka, Shinsuke Takagi, Naoyuki Uchida, Nahoko Suzuki, Akiko Sone, Yuho Najima, Hidetoshi Ozawa, Atsushi Wake, Shuichi Taniguchi, Leonard D Shultz, Osamu Ohara, Fumihiko Ishikawa
- Journal Title
  
  Sci. Transl. Med.
  
  Volume: 2(17) Issue: 17 Pages: 17-9
- DOI
  10.1126/scitranslmed.3000349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790334
[Journal Article] Immunoposttranscriptomics-マクロファージ様細胞を用いた網羅的な翻訳制御解析を例に-2010
- Author(s)
  北村浩
- Journal Title
  
  日本病態生理学会誌
  
  Volume: 19 Pages: 39-48
- Data Source
  KAKENHI-PROJECT-21790334
[Journal Article] Naturally occurring regulatory dendritic cells regulate murine cutaneous graft-versus-host disease2009
- Author(s)
  Kaori Sato, Kawori Eizumi, Tomohiro Fukaya, Shigeharu Fujita, Yumiko Sato, Hideaki Takagi, Mai Yamamoto, Naohide Yamashita, Atsushi Hijikata, Hiroshi Kitamura, Osamu Ohara, Sho Yamasaki, Takashi Saito, Katsuaki Sato
- Journal Title
  
  Blood
  
  Volume: 113(19) Issue: 19 Pages: 4780-4789
- DOI
  10.1182/blood-2008-10-183145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790334
[Journal Article] Deficiency of the oxidative damage-specific DNA glycosylase NAIL1 leads to reduced germinal center B cell expansion2009
- Author(s)
  Hiromi Mori, Rika Ouchida, Atsushi Hijikata, Hiroshi Kitamura, Osamu Ohara, Yingqian Li, Xiang Gao, Akira Yasui, R. Stephan Lloyd, Ji-Yang Wang
- Journal Title
  
  DNA Repair(Amst)
  
  Volume: 8(11) Issue: 11 Pages: 1328-1332
- DOI
  10.1016/j.dnarep.2009.08.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790334
[Journal Article] Mina an Il4 repressor, controls T helper type 2 bias2009
- Author(s)
  Mariko Okamoto, Melanie Van Stry, Linda Chung, Madoka Koyanagi, Xizhang Sun, Yoshie Suzuki, Osamu Ohara, Hiroshi Kitamura, Atsushi Hijikata, Masato Kubo, Mark Bix
- Journal Title
  
  Nat. Immunol.
  
  Volume: 10(8) Issue: 8 Pages: 872-879
- DOI
  10.1038/ni.1747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790334
[Journal Article] M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex2009
- Author(s)
  Koji Hase, Shunsuke Kimura, Hiroyuki Takatsu, Masumi Ohmae, Sayaka Kawano, Hiroshi Kitamura, Masatoshi Ito, Hiroshi Watarai, C. Clayton Hazelett, Charles Yeaman, Hiroshi Ohno
- Journal Title
  
  Nat. CellBiol
  
  Volume: 11(12) Issue: 12 Pages: 1427-1432
- DOI
  10.1038/ncb1990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790334
[Journal Article] Dentification of a novel subset of CD8+dendritic cells responsible for tolerance induction of cell-associated antigens2009
- Author(s)
  Chun-Hong Qin, Yasunobu Miyake, Hitomi Kaise, Hiroshi Kitamura, Osamu Ohara, Masato Tanaka
- Journal Title
  
  J. Immunol.
  
  Volume: 182(7) Issue: 7 Pages: 4127-4136
- DOI
  10.4049/jimmunol.0803364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790334
[Journal Article] Genome-wide identification and characterization of transcripts translationally regulated by bacterial lipopolysaccharide in macrop hage-like J774.1 cells2008
- Author(s)
  Kitamura H, et. al.
- Journal Title
  
  Physiological Genomics 32(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17780223
[Journal Article] DNA/RNA試料調製2004
- Author(s)
  北村浩他
- Journal Title
  
  蛋白質・核酸・酵素 49・11
  
  Pages: 752-756
- Data Source
  KAKENHI-PROJECT-14760184
[Patent] Leukemia Stem Cell Markers2011
- Inventor(s)
  石川文彦、小原收、齊藤頼子、北村浩、土方敦司、小澤秀俊
- Industrial Property Rights Holder
  理化学研究所
- Acquisition Date
  2011-04-11
- Overseas
- Data Source
  KAKENHI-PROJECT-21790334
[Presentation] 視床下部腹内側核のUSP2による血糖値の調節とその仕組み2023
- Author(s)
  藤本　政毅, 橋本　茉由子, 今野　幸太郎, 戸田　知得, 渡辺　雅彦, 北村　浩
- Organizer
  第31回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-21K06001
[Presentation] 骨格筋のUSP2によるインスリン感受性の制御2023
- Author(s)
  藤本政毅, 橋本茉由子, 高橋英機, 北村浩
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06001
[Presentation] 骨格筋のユビキチン特異的プロテアーゼ(USP)2によるインスリン感受性の制御2023
- Author(s)
  藤本　政毅, 橋本　茉由子, 北村　浩
- Organizer
  第166回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06001
[Presentation] 視床下部のユビキチン特異的プロテアーゼ2による血糖値維持機構2022
- Author(s)
  藤本政毅、橋本茉由子、今野幸太郎、李明亮、山田柚衣、山下晃矢、戸田知得、戸村道夫、渡辺雅彦、稲波修、北村浩
- Organizer
  第165回日本獣医学会・日本実験動物医学会
- Data Source
  KAKENHI-PROJECT-21K06001
[Presentation] マクロファージのUSP2による凍結精子の活性維持2022
- Author(s)
  橋本茉由子、北村　浩
- Organizer
  第18回HALAS学術集会
- Data Source
  KAKENHI-PROJECT-21K06001
[Presentation] 精巣マクロファージに発現するUSP2による精子運動機能の制御2022
- Author(s)
  北村　浩、橋本茉由子、木村俊介、渡邊敬文、高橋英機、永野昌志
- Organizer
  第30回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-21K06001
[Presentation] 精巣マクロファージに発現するUSP2による精子運動機能の制御2022
- Author(s)
  北村　浩、橋本茉由子、木村俊介、渡邊敬文、高橋英機、永野昌志
- Organizer
  第29回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-18K06035
[Presentation] 精巣マクロファージに発現するUSP2による精子運動機能の制御2022
- Author(s)
  北村　浩、橋本茉由子、木村俊介、渡邊敬文、高橋英機、永野昌志
- Organizer
  第29回日本病態生理学会
- Data Source
  KAKENHI-PROJECT-21K06001
[Presentation] 視床下部腹内側核のUSP2による血糖値維持における役割とその機序2022
- Author(s)
  藤本政毅、橋本茉由子、北村　浩
- Organizer
  第18回HALAS学術集会
- Data Source
  KAKENHI-PROJECT-21K06001
[Presentation] 視床下部腹内側核のUSP2による血糖値の調節とその仕組み2022
- Author(s)
  藤本政毅、橋本茉由子、今野幸太郎、戸田知得、渡辺雅彦、北村浩
- Organizer
  第31回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-21K06001
[Presentation] マクロファージのユビキチンプロテアーゼ２が凍結精子の機能に与える役割2021
- Author(s)
  橋本茉由子、木村俊介、菅野智裕、柳川洋二郎、渡邉敬文、高橋英機、永野昌志、北村　浩
- Organizer
  第164回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06035
[Presentation] 精巣マクロファージのユビキチン特異的プロテアーゼ2が精子機能に与える影響2020
- Author(s)
  橋本茉由子、木村俊介、菅野智裕、柳川洋二郎、渡邉敬文、岡部潤、高橋英機、永野昌志、北村　浩
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06035
[Presentation] ユビキチン特異的プロテアーゼ２による筋芽細胞のミトコンドリアの機能維持と活性酸素の役割2019
- Author(s)
  橋本茉由子、太田葉瑠、齊藤菜津子、山本久美子、稲波修、北村　浩
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06035
[Presentation] Droplet-EP法による家畜細胞へのプラスミド・組前タンパク質の導入2019
- Author(s)
  石野武志、栗田弘史、北村　浩
- Organizer
  第162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06035
[Presentation] 筋芽細胞におけるUSP2によるミトコンドリア機能制御2019
- Author(s)
  太田葉瑠、橋本茉由子、齊藤奈津子、山本久美子、中澤康裕、稲波修、北村　浩
- Organizer
  第162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06035
[Presentation] 新たなエネルギー代謝制御酵素USP2の視床下部での発現と機能2019
- Author(s)
  橋本茉由子、今野幸太郎、渡辺雅彦、北村　浩
- Organizer
  第24回グリアクラブ
- Data Source
  KAKENHI-PROJECT-18K06035
[Presentation] 視床下部ユビキチン特異的プロテアーゼ2の発現と血糖調節に対する役割2018
- Author(s)
  橋本茉由子、Lee Ming Liang、木村俊介、戸田知得、高橋英機、北村　浩
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] マクロファージ選択的ユビキチン特異的プロテアーゼ2欠損マウスの精巣機能の評価2018
- Author(s)
  天笠美聡、菅野智裕、木村俊介、栁川洋二郎、岩永敏彦、高橋英機、永野昌志、北村　浩
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06035
[Presentation] 視床下部ユビキチン特異的プロテアーゼ2の発現と血糖調節に対する役割2018
- Author(s)
  橋本茉由子、Lee Ming Liang、木村俊介、戸田知得、高橋英機、北村　浩
- Organizer
  第４１回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06035
[Presentation] ユビキチン特異的プロテアーゼ２の視床下部における発現と血糖調節における役割2018
- Author(s)
  橋本茉由子、李　明亮、木村俊介、戸田知得、高橋英機、北村　浩
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] マクロファージ選択的ユビキチン特異的プロテアーゼ2欠損マウスの精巣機能の評価2018
- Author(s)
  天笠美聡、菅野智裕、木村俊介、栁川洋二郎、岩永敏彦、高橋英機、永野昌志、北村　浩
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] マクロファージに選択的なUsp2ノックアウトマウスの精巣機能の評価2018
- Author(s)
  天笠美聡、菅野智裕、木村俊介、栁川洋二郎、岩永敏彦、高橋英機、永野昌志、北村　浩
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] ユビキチン特異的プロテアーゼ２の視床下部における発現と血糖調節における役割2018
- Author(s)
  橋本茉由子、Lee Ming Liang、木村俊介、戸田知得、高橋英機、北村　浩
- Organizer
  第32回北海道薬物作用談話会
- Data Source
  KAKENHI-PROJECT-18K06035
[Presentation] 視床下部ユビキチン特異的プロテアーゼ2の血糖値に対するフィードバック制御2018
- Author(s)
  橋本茉由子、李　明亮、木村俊介、戸田知得、高橋英機、北村　浩
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06035
[Presentation] マクロファージに選択的なUsp2ノックアウトマウスの精巣機能の評価2018
- Author(s)
  天笠美聡、菅野智裕、木村俊介、栁川洋二郎、岩永敏彦、高橋英機、永野昌志、北村　浩
- Organizer
  第４１回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06035
[Presentation] ユビキチン特異的プロテアーゼ２の視床下部における発現と血糖調節における役割2018
- Author(s)
  橋本茉由子、Lee Ming Liang、木村俊介、戸田知得、高橋英機、北村　浩
- Organizer
  第32回北海道薬物作用談話会
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] ゲノミクスの最近の流れ-動物実験に如何に使用するか-2017
- Author(s)
  北村　浩
- Organizer
  第28回東北動物実験研究会
- Invited
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] インスリン誘導性低血糖時のマウス視床下部におけるUsp2の発現局在2017
- Author(s)
  橋本茉由子、戸田知得、高橋英機、北村　浩
- Organizer
  ２０１７年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] マクロファージのUSP2はOCTを修飾し、炎症性サイトカインの産生を抑制する2017
- Author(s)
  北村　浩
- Organizer
  ２０１７年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] プロポリスエタノール抽出物によるMDSC(Myeloid Derived Suppressor Cell）の誘導2016
- Author(s)
  鷲尾浩平、藤本純平、北村　浩
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源科学部、藤沢市
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] マクロファージで発現するユビキチン特異的プロテアーゼ２による抗糖尿病効果のメカニズム2016
- Author(s)
  北村　浩、齊藤奈津子、天笠美聡、宮本智美、木村俊介、高橋英機
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、横浜市
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] 視床下部摂食調節経路におけるユビキチン特異的イソペプチダーゼ２に発現2016
- Author(s)
  馬場海陸、田代あすか、高橋英機、北村　浩
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源科学部、藤沢市
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] 高脂肪餌長期給餌モデルを用いたマクロファージで発現するUSP2の抗糖尿病効果の検討2016
- Author(s)
  齊藤奈津子、宮本智美、三好一郎、高橋英機、北村　浩
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源科学部、藤沢市
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] ユビキチン特異的プロテアーゼ(USP)2の成熟骨格筋における発現・機能解析2016
- Author(s)
  田代あすか、福島早苗、高橋英機、北村　浩
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源科学部、藤沢市
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] マクロファージの炎症応答におけるユビキチン特異的プロテアーゼ（USP）2の役割2015
- Author(s)
  澤　尚樹、鷲尾浩平、宮本智美、三好一郎、高橋英機、北村　浩
- Organizer
  第158回日本獣医学会学術集会
- Place of Presentation
  北里大学獣医学部
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] プロポリスエタノール抽出物は筋芽細胞におけるサイトカインの産生を刺激する。2015
- Author(s)
  吉川勇輝、鷲尾浩平、小林真央、齊藤奈津子、天笠美聡、北村　浩
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] ブラジル産グリーンプロポリスの高2型糖尿病効果についての検討2015
- Author(s)
  鷲尾浩平、木村俊介、直江吉則、宮本智美、三好一郎、北村　浩
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] 脂肪組織内免疫細胞を標的とした糖尿病予防・治療法の開発-プロポリスとUSP2を例に-2015
- Author(s)
  北村　浩
- Organizer
  第２９回北海道薬物作用談話会
- Place of Presentation
  酪農学園大学
- Year and Date
  2015-08-08
- Invited
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] プロポリスの脂肪内免疫細胞を介した抗２型糖尿病効果-遺伝性肥満マウスを用いた検討-2015
- Author(s)
  鷲尾浩平、木村俊介、直江吉則、宮本智美、三好一郎、北村　浩
- Organizer
  第158回日本獣医学会学術集会
- Place of Presentation
  北里大学獣医学部
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] Ubiquitin-specific protease2 A inhibits adipose tissue inflammation2015
- Author(s)
  Asuka Tashiro, Shunsuke Kimura, Tomomi Miyamoto, Sanae Fukushima, Ichiro Miyoshi, Yoshinori, Shimamoto, Eiki Takahashi , Hiroshi Kitamura
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06805
[Presentation] マクロファージの USP2 - 新たな糖尿病制御分子 -2014
- Author(s)
  北村浩，木村俊介，岡部潤，宮本智美，嶋本良則，直江吉則，戸田智得，岡本士毅，三好一郎
- Organizer
  日本実験動物医学会シンポジウム（第157回日本獣医学会学術集会）
- Place of Presentation
  北海道大学（北海道）
- Year and Date
  2014-09-10
- Data Source
  KAKENHI-PROJECT-24500495
[Presentation] ob/obマウスの２型糖尿病進行に対するプロポリスの抑制効果-腸管膜脂肪組織における免疫細胞の役割-2013
- Author(s)
  北村　浩、直江吉則、木村俊介、宮本智美、三好一郎
- Organizer
  第８３回東海実験動物研究会
- Place of Presentation
  名古屋市立大学（愛知県）
- Data Source
  KAKENHI-PROJECT-24500495
[Presentation] マクロファージ分子M-modによる肥満症・糖尿病の制御2013
- Author(s)
  北村　浩、木村　俊介、嶋本　良則、岡部　潤、宮本　智美、直江　吉則、岡本　士毅、戸田　知得、Assam El-Osta、三好　一郎
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜大学（岐阜県）
- Data Source
  KAKENHI-PROJECT-24500495
[Presentation] マクロファージ分子M-modによる肥満症・糖尿病の制御2013
- Author(s)
  北村　浩、木村俊介、嶋本良則、岡部　潤、宮本智美、直江吉則、岡本士毅、戸田知得、Assam El-Osta、三好一郎
- Organizer
  第１５６回日本獣医学会学術集会
- Place of Presentation
  岐阜大学（岐阜県）
- Data Source
  KAKENHI-PROJECT-24500494
[Presentation] Roles of a macrophage molecule M-mod in type 2 diabetes.2012
- Author(s)
  Kitamura H, Ito M, Kimura S, Shimamoto Y, Miyamoto T, Watarai H, Okabe J, Iwanaga T, Ohara O, Miyoshi I
- Organizer
  Experimental Biology 2012.
- Place of Presentation
  San Diego Convention Center (San Diego, USA)
- Data Source
  KAKENHI-PROJECT-24500495
[Presentation] Possible involvement of a novel macrophage molecule in pathogenesis of type 2 diabetes2012
- Author(s)
  Hiroshi Kitamura, Shunsuke Kimura, Tomomi Miyamoto, Masatoshi Ito, Yoshinori Shimamoto, Jun Okabe, Yoshinori Naoe, Koji Hase, Osamu Ohara, Ichiro Miyoshi
- Organizer
  The 4th EMBO meeting
- Place of Presentation
  アクロポリス国際会議場（ニース、フランス）
- Data Source
  KAKENHI-PROJECT-24500494
[Presentation] A macrophage modulator has potential to repress metabolic deterioration2012
- Author(s)
  Hiroshi Kitamura, Shunsuke Kimura, Masatoshi Ito, Yoshinori Shimamoto, Tomomi Miyamoto, Jun Okabe, Hiroshi Watari, Osamu Ohara, Ichiro Miyoshi
- Organizer
  IEIIS2012
- Place of Presentation
  学術総合センター（東京都）
- Data Source
  KAKENHI-PROJECT-24500494
[Presentation] Roles of a macrophage molecule M-mod in type 2 diabetes2012
- Author(s)
  Hiroshi Kitamura, Masatoshi Ito, Shunsuke Kimura, Yoshinori Shimamoto, Tomomi Miyamoto, Hiroshi Watarai, Jun Okabe, Toshihiko Iwanaga, Osamu Ohara, Ichiro Miyoshi
- Organizer
  Experimental Biology 2012
- Place of Presentation
  サンディエゴコンベンションセンター（サンディエゴ、アメリカ）
- Data Source
  KAKENHI-PROJECT-24500494
[Presentation] Possible involvement of a novel macrophage molecule in pathogenesis of type 2 diabetes.2012
- Author(s)
  Kitamura H, Ohara O, Kimura S, Miyamoto T, Ito M, Shimamoto Y, Naoe Y, Okabe J, Hase Ｋ，Watarai H, Miyoshi I
- Organizer
  The 4th EMBO meeting
- Place of Presentation
  Nice Acropolis Convention Center (Nice, France)
- Data Source
  KAKENHI-PROJECT-24500495
[Presentation] マクロファージの新たな機能制御分子による2型糖尿病関連分子の発現調節2011
- Author(s)
  北村浩
- Organizer
  第152回日本獣医学会学術集会
- Place of Presentation
  大阪府立大学(大阪府)
- Year and Date
  2011-09-20
- Data Source
  KAKENHI-PROJECT-21790334
[Presentation] モダンゲノミクスの成果と展望-如何に使いこなすか?-2011
- Author(s)
  北村浩
- Organizer
  東海実験動物研究会2011年例会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PROJECT-21790334
[Presentation] マクロファージの新たな機能制御分子による2型糖尿病関連分子の発現調節2011
- Author(s)
  北村浩、伊藤誠敏、木村俊介、嶋本良則、小林敦夫、菊口千智、岡部潤、渡会浩志、小原收、三好一郎
- Organizer
  第152回日本獣医学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21790334
[Presentation] Immunoposttranscriptomics:マクロファージ系細胞を用いた網羅的な翻訳制御解析を例に2010
- Author(s)
  北村浩
- Organizer
  第20回病態生理学会(サテライトセミナー)
- Place of Presentation
  奈良県立医科大学、橿原
- Year and Date
  2010-01-22
- Data Source
  KAKENHI-PROJECT-21790334
[Presentation] 骨髄性白血病細胞株におけるUSP2の発現および機能解析2009
- Author(s)
  北村浩, 他
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21790334
[Presentation] マウスマクロファージ様 J774.l細胞のタンパク質翻訳に対するLpsの効果2007
- Author(s)
  北村浩他
- Organizer
  日本分子生物学会・日本生化学会合同年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-17780223
[Presentation] ブラジル産プロポリスの糖尿病発症予防効果-脂肪組織中の免疫細胞をターゲットとした予防メカニズムの検証
- Author(s)
  北村浩
- Organizer
  日本農芸化学会
- Place of Presentation
  岡山大学(岡山県）
- Year and Date
  2015-03-27 – 2015-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-24500494
[Presentation] マクロファージのＵＳＰ２による２型糖尿病制御の可能性
- Author(s)
  北村浩，木村俊介，岡部潤，宮本智美，嶋本良則，直江吉則，戸田智得，岡本士毅，三好一郎
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-24500495
[Presentation] マクロファージのUSP2による２型糖尿病制御の可能性
- Author(s)
  北村　浩、木村俊介、宮本智美、岡部潤、嶋本良則、直江吉則、三好一郎
- Organizer
  日本実験動物学会
- Place of Presentation
  札幌コンベンションセンター(北海道）
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-24500494
[Presentation] マクロファージのUSP2-新たな糖尿病制御分子-
- Author(s)
  北村浩、木村俊介、岡部潤、宮本智美、嶋本良則、直江吉則、戸田知得、岡本士毅、三好一郎
- Organizer
  日本獣医学会
- Place of Presentation
  北海道大学（北海道）
- Year and Date
  2014-09-09 – 2014-09-12
- Invited
- Data Source
  KAKENHI-PROJECT-24500494

1. MIYOSHI Ichiro (10183972)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
2. OKAMOTO Shiki (40342919)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. TAKAHASI Eiki (40446521)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
4. KIMURA Shunsuke (40444525)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
5. OKAMURA Tadashi (00333790)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. OHARA Osamu (20370926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. ISHIKAWA Fumihiko (30403918)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. SHIMAMOTO Yoshinori (30552046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAOE Yoshinori (50392048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. IWANAGA Toshihiko (10160128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. Fujikura Daisuke (70547794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 渡邉敬文 (50598216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 江口暁子 (00598980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. OKABE jun

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. MOTOHASHI Shinichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. OKADA Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. HAMAMOTO Shuzo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. TAGUCHI Kazumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 佐藤英世

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 犬塚博之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 清水康平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 福本敏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 谷口克

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 戸澤啓一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 郡健二郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 安井孝周

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KITAMURA Hiroshi 北村 浩

北村 浩 キタムラ ヒロシ

Research Projects

Research Products

Co-Researchers

骨格筋のユビキチンプロテアーゼに注目した糖尿病サルコペニアモデルの構築と病態解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生理的マイトファジーに着眼したブロイラーの異常胸肉の病態解明と抑制方法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of roles of ubiquitin-specific proteases in NAFLD/NASH pathogenesis using cell-specific gene-engineered mouse modelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of death receptor 6 in anti-tumor immunity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of physiologocal roles of USP2 in energy metabolism by using cell-specific knockout modelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The elucidation of molecular mechanism of Epithelial ovarian cancer (EOC) model mouse

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of a novel key regulatory molecule, USP2, in energy homeostasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Modulatory effects of macrophage M-mod/USP2 on type2 diabetesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of animal model for the blood sugar regulation by glycosphingolipids and study on the molecular pathogenesis of inflammation in adipose tissue

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a method for isolating canine cancer initiating cells and a new cancer therapy based on their gene expression analyses

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive analysis of splicing variants characteristic of acute myelogenous leukemia stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マクロファージのLPS応答における翻訳調整の役割と分子メカニズムの網羅的解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新しいIκBタンパク質MAILのLPS炎症反応における役割および作用機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

KITAMURA Hiroshi 北村浩

北村浩キタムラヒロシ

[Book] ゲノム編集食品~農林水産分野への応用問持続的社会の実現～　第2編4章12021