UEBA Hiroto 上羽洋人

Researcher Number	80316546
Affiliation (based on the past Project Information) *help	2008 – 2013: Jichi Medical University, 医学部, 講師 2000 – 2003: 自治医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine Except Principal Investigator Metabolomics
Keywords	Principal Investigator 動脈硬化 / THP-1 / HUVEC / MMP / HGF / VEGF / シグナル伝達 / アポトーシス / 血管内皮細胞 / gene cloning … More / atherpsclerosis / apoptosis / monocyte / vascular endothelial cells / 遺伝子クローニング / 単球 / マクロファージ / erythropoietin / WHHLMIウサギ / アゴニスト / エリスロポエチン … More Except Principal Investigator VEGF / MITCHONDRIAL ELECTRON TRANSPORT / NO SYNTHASE / NITRIC OXIDE / REACTIVE OXYGEN SPECIES / NADPH OXIDASE / HYPOXIA / K-ATPチャンネル / ATP / HNF-4 / 一酸化窒素 / NADPHオキシダーゼ / 一酸化窒素合成酵素 / ミトコンドリア電子伝達系 / 一酸化炭素 / 活性酸素 / NADPHオキシターゼ / 低酸素 Less

Molecular mechanisms of suppression of macrophage foam cell formation by an erythropoietin receptor agonistPrincipal Investigator
- Principal Investigator
  
  UEBA HIROTO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Jichi Medical University
Anti-atherosclerotic effects of an erythropoietin receptor agonistPrincipal Investigator
- Principal Investigator
  
  UEBA Hiroto
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Jichi Medical University
Analysis of antiapoptotic genes induced in vascular endothelial cells by monocyte adhesion.Principal Investigator
- Principal Investigator
  
  UEBA Hiroto
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Jichi Medical School
Regulation of matrix metalloprotcase-9 production induced by monocyte-vascular endothelial cell interaction - role of hepatocyte growth factor and vascular endothelial growth.Principal Investigator
- Principal Investigator
  
  UEBA Hiroto
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Omiya Medical Center, Jichi Medical School
THE ELUCIDATION OF THE OXYGEN SENSING AND INTRACELLULAR SIGNALING SYSTEM.
- Principal Investigator
  
  KUROKI Masatoshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  JICHI MEDICAL SCHOOL

All 2014 2013 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Suppression of coronary atherosclerosis by a helix B surface peptide, a nonerythropoietic tissue- protective compound derived from erythropoietin2013
- Author(s)
  Ueba H, Shiomi M, Brines M, Yamin M, Kobayashi T, Ako J, Momomura S, Cerami A, Kawakami M.
- Journal Title
  
  Mol Med.
  
  Volume: 19(1) Pages: 195-202
- Data Source
  KAKENHI-PROJECT-23591108
[Journal Article] Suppression of coronary atherosclerosis by helix B surface peptide, a nonerythropoietic, tissue-protective compound derived from erythropoietin.2013
- Author(s)
  Ueba H, Shiomi M, Brines M, Yamin M, Kobayashi T, Ako J, Momomura SI, Cerami A, Kawakami M
- Journal Title
  
  Molecular Medicine
  
  Volume: 19 Issue: 1 Pages: 195-202
- DOI
  10.2119/molmed.2013.00037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300157, KAKENHI-PROJECT-23591108
[Journal Article] Reply to Abdelwahid and Smith: The effect on cardiomyocytes of helix B-surface peptide (HBSP), a peptide with cell-protective but not erythropoietic activities of erythropoietin2011
- Author(s)
  Kawakami M, Ueba H, Brines M, Yamin M, Umemoto T, Ako J, Momomura S, and Cerami A
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 108(6) Issue: 6
- DOI
  10.1073/pnas.1012530108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591108
[Journal Article] Reply to Abdelwahid and Smith : The effect on cardiomyocytes of helix B-surface peptide (HBSP), a peptide with cell-protective but not erythro- poietic activities of erythropoietin2011
- Author(s)
  Masanobu Kawakami, Hiroto Ueba, Michael Brines, Michael Yamin, Tomio Umemoto, Junya Ako, Shin-ichi Momomura, and Anthony Cerami
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 108(6)
- Data Source
  KAKENHI-PROJECT-23591108
[Journal Article] Reply to Abdel Wahid, Smith : The effect on cardiomyocytes of helix B-surface peptide (HBSP), a peptide with cell-protective but not erythropoietic activities of erythropoietin2011
- Author(s)
  Masanobu Kawakami, Hiroto Ueba
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: 108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590887
[Journal Article] Reply to Abdelwahid and Smith : The effect on cardiomyocytes of helix B-surface peptide (HBSP), a peptide with cell-protective but not erythropoietic activities of erythropoietin.2011
- Author(s)
  Masanobu Kawakami, Hiroto Ueba, Michael Brines, Michael Yamin, Tomio Umemoto, Junya Ako, Shin-ichi Momomura, Anthony Cerami
- Journal Title
  
  Proc Natl Acad Sci USA. 108(6)
- Data Source
  KAKENHI-PROJECT-20590887
[Journal Article] Cardioprotection by a nonerythropoietic, tissue-protective peptide mimicking the 3D structure of erythropoietin2010
- Author(s)
  Hiroto Ueba
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: 107 Pages: 14357-14362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590887
[Journal Article] Cardioprotection by a nonerythropoietic, tissue-protective peptide mimicking the 3D structure of erythropoietin.2010
- Author(s)
  Hiroto Ueba, Michael Brines, Michael Yamin, Tomio Umemoto, Junya Ako, Shin-ichi Momomura, Anthony Cerami, Masanobu Kawakami
- Journal Title
  
  Proc Natl Acad Sci USA. 107(32)
  
  Pages: 14357-14362
- Data Source
  KAKENHI-PROJECT-20590887
[Journal Article] C-Reactive protein induces endothelial cell apoptosis and matrix metalloproteinase-9 production in human mononuclear cells : Implications for the destabilization of atherosclerotic plaque.2008
- Author(s)
  Aoi Nabata, Masatoshi Kuroki, Hiroto Ueba, Shigemasa Hashimoto, Tomio Umemoto, Hiroshi Wada, Takanori Yasu, Muneyasu Saito, Shin-ichi Momomura, Masanobu Kawakami
- Journal Title
  
  Atherosclerosis 196(1)
  
  Pages: 129-135
- Data Source
  KAKENHI-PROJECT-20590887
[Journal Article] Effects of Thiazolidinediones on In- Stent Restenosis : A Review of IVUS Studies
- Author(s)
  Yasu T, Ueba H, Katayama T, Kawakami M.
- Journal Title
  
  Intravascular Ultrasound, Yasuhiro Honda (Ed.)
  
  Volume: (ISBN :978-953-307-900-4)(InTech 2012)
- URL
  http://www.intechopen.com/books/intravascular-ultrasound/effects-of-thiazolidinedione-on-in-stent-restenosis-a-review-of-ivus-studies
- Data Source
  KAKENHI-PROJECT-23591108
[Presentation] Helix B surface peptide, a nonerythropoietic erythropoietin derivative, modifies macrophage polarization and prevents progression of coronary atherosclerotic lesions2014
- Author(s)
  Ueba, H., Shiomi, M., Brines, M., Yamin M., Cerami, A., Momomura, S.
- Organizer
  The 78th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Tokyo
- Year and Date
  2014-03-22
- Data Source
  KAKENHI-PROJECT-23591108
[Presentation] Suppression of coronary atherosclerosis by a helix B surface peptide, a nonerythropoietic tissue- protective compound derived from erythro- poietin2013
- Author(s)
  Ueba, H., Shiomi, M., Brines, M., Yamin, M., Ako, J., Momomura, S., Cerami, A., Kawakami, M.
- Organizer
  The 77th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Yokohama
- Year and Date
  2013-03-15
- Data Source
  KAKENHI-PROJECT-23591108
[Presentation] Suppression of coronary atherosclerosis by a helix B surface peptide, a nonerythropoietic tissue-protective compound derived from erythropoietin2013
- Author(s)
  Ueba, H., Shiomi, M., Brines, M., Yamin, M., Ako, J., Momomura, S., Cerami, A., Kawakami
- Organizer
  The 77th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23591108
[Presentation] 慢性心不全動物モデルにおける非造血性エリスロポエチン誘導体による心筋保護作用―抗アポトーシス効果による適応2013
- Author(s)
  上羽洋人, Michael Brines, Michael Yamin, Anthony Cerami,梅本富士,阿古潤哉,川上正舒,百村伸一
- Organizer
  第17回日本適応医学会学術集会
- Place of Presentation
  さいたま市
- Year and Date
  2013-06-29
- Data Source
  KAKENHI-PROJECT-23591108
[Presentation] Cardioprotective Prop- erties of Helix B Surface Peptide, a Nonerythropoietic Derivative Mimicking the 3D Structure of Erythropoietin2011
- Author(s)
  Ueba, H., Brines, M., Yamin, M., Umemoto, T., Ako, J., Momomura, S., Cerami, A., Kawakami, M.
- Organizer
  The 75th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Yokohama
- Year and Date
  2011-08-03
- Data Source
  KAKENHI-PROJECT-23591108
[Presentation] Cardioprotective Properties of Helix B Surface Peptide, a Nonerythropoietic Derivative Mimicking the 3D Structure of Erythropoietin2011
- Author(s)
  Ueba, H., Brines, M., Yamin, M., Umemoto, T., Ako, J., Momomura, S., Cerami, A., Kawakami, M.
- Organizer
  The 75th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-23591108
[Presentation] Cardiomyocyte protection by a nonerythropoietic, tissue-protective peptide derived from erythropoietin.2010
- Author(s)
  Ueba, H, Brines, M, Yamin, M, Umemoto, T, Ako, J, Momomura, S, Cerami, A, Kawakami, M.
- Organizer
  第74回日本循環器学会総会
- Place of Presentation
  京都市
- Year and Date
  2010-03-05
- Data Source
  KAKENHI-PROJECT-20590887
[Presentation] Cardiomyocyte Protection by a Nonerythropoietic, Tissue-protective Peptide Derived from Erythropoietin2010
- Author(s)
  Hiroto Ueba
- Organizer
  第74回日本循環器学会総会
- Place of Presentation
  京都市
- Year and Date
  2010-03-05
- Data Source
  KAKENHI-PROJECT-20590887
[Presentation] Role of osteopontin and αvβ3 integrin in the regulation of endothelial cell survival by endothelial cell-monocyte interaction2010
- Author(s)
  Hiroto Ueba
- Organizer
  第42回日本動脈硬化学会総会
- Place of Presentation
  岐阜市
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-20590887
[Presentation] Role of osteopontin and αvβ3 integrin in the regulation of endothelial cell survival by endothelial cell-monocyte interaction.2010
- Author(s)
  Ueba, H, Hashimoto, S, Umemoto, T, Ako, J, Momomura, S, Kawakami, M.
- Organizer
  第42回日本動脈硬化学会総会
- Place of Presentation
  岐阜市
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-20590887
[Presentation] Induction of Endothelial Cell Apoptosis and Monocyte Matrix Metallo-proteinase-9 Production by C-Reactive Protein2009
- Author(s)
  Hiroto Ueba
- Organizer
  第73回日本循環器学会総会
- Place of Presentation
  大阪市
- Year and Date
  2009-03-21
- Data Source
  KAKENHI-PROJECT-20590887
[Presentation] Induction of endothelial cell apoptosis and monocyte matrix metalloproteinase-9 production by C-reactive protein.2009
- Author(s)
  Ueba, H, Nabata, A, Kuroki, M, Hashimoto, S, Umemoto, T, Sugawara, Y, Kubo, N, Momomura, S, Kawakami, M.
- Organizer
  第73回日本循環器学会総会
- Place of Presentation
  大阪市
- Year and Date
  2009-03-21
- Data Source
  KAKENHI-PROJECT-20590887

1. KAWAKAMI Masanobu (40161286)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. KUROKI Masatoshi (90215096)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. YASU Takanori (40265278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 川上正

# of Collaborated Projects: 0 results

# of Collaborated Products: 16 results
5. 塩見雅志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

UEBA Hiroto 上羽 洋人

Research Projects

Research Products

Co-Researchers

Molecular mechanisms of suppression of macrophage foam cell formation by an erythropoietin receptor agonistPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Anti-atherosclerotic effects of an erythropoietin receptor agonistPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of antiapoptotic genes induced in vascular endothelial cells by monocyte adhesion.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of matrix metalloprotcase-9 production induced by monocyte-vascular endothelial cell interaction - role of hepatocyte growth factor and vascular endothelial growth.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

THE ELUCIDATION OF THE OXYGEN SENSING AND INTRACELLULAR SIGNALING SYSTEM.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Suppression of coronary atherosclerosis by a helix B surface peptide, a nonerythropoietic tissue- protective compound derived from erythropoietin2013

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of coronary atherosclerosis by helix B surface peptide, a nonerythropoietic, tissue-protective compound derived from erythropoietin.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reply to Abdelwahid and Smith: The effect on cardiomyocytes of helix B-surface peptide (HBSP), a peptide with cell-protective but not erythropoietic activities of erythropoietin2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reply to Abdelwahid and Smith : The effect on cardiomyocytes of helix B-surface peptide (HBSP), a peptide with cell-protective but not erythro- poietic activities of erythropoietin2011

Author(s)

Journal Title

Data Source

[Journal Article] Reply to Abdel Wahid, Smith : The effect on cardiomyocytes of helix B-surface peptide (HBSP), a peptide with cell-protective but not erythropoietic activities of erythropoietin2011

Author(s)

Journal Title

Data Source

[Journal Article] Reply to Abdelwahid and Smith : The effect on cardiomyocytes of helix B-surface peptide (HBSP), a peptide with cell-protective but not erythropoietic activities of erythropoietin.2011

Author(s)

Journal Title

Data Source

[Journal Article] Cardioprotection by a nonerythropoietic, tissue-protective peptide mimicking the 3D structure of erythropoietin2010

Author(s)

Journal Title

Data Source

[Journal Article] Cardioprotection by a nonerythropoietic, tissue-protective peptide mimicking the 3D structure of erythropoietin.2010

Author(s)

Journal Title

Data Source

[Journal Article] C-Reactive protein induces endothelial cell apoptosis and matrix metalloproteinase-9 production in human mononuclear cells : Implications for the destabilization of atherosclerotic plaque.2008

Author(s)

Journal Title

Data Source

[Journal Article] Effects of Thiazolidinediones on In- Stent Restenosis : A Review of IVUS Studies

Author(s)

Journal Title

URL

Data Source

[Presentation] Helix B surface peptide, a nonerythropoietic erythropoietin derivative, modifies macrophage polarization and prevents progression of coronary atherosclerotic lesions2014

Author(s)

Organizer

UEBA Hiroto 上羽洋人