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kamai takao  釜井 隆男

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Kamai Takao  釜井 隆男

KAMAI Takao  釜井 隆男

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Researcher Number 80316562
Other IDs
Affiliation (Current) 2025: 獨協医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2014 – 2022: 獨協医科大学, 医学部, 教授
2003 – 2005: Dokkyo University School of Medicine, Department of Urology, Assistant professor, 医学部, 講師
2000 – 2004: 獨協医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Urology / Urology / Basic Section 56030:Urology-related
Except Principal Investigator
Urology
Keywords
Principal Investigator
腎細胞癌 / Renal cell carcinoma / Nrf2 / Rho / mRNA / Prognosis / Recurrence / Metastasis / Invasion / ROCK … More / GTPase / 腎癌 / Akt / HLRCC / RT-PCR法 / NGS / Keap1 / SDH / FH / インターフェロン / 免疫 / PD-L1 / renal cell carcinoma / Warburg effect / 免疫回避 / 代謝異常 / metastasis / real time RT-PCR / interferon alpha receptor / 精巣癌 / 膀胱癌 / IFNAR2 / IFNAR1 / western blotting / real-time RT-PCR / インターフェロンαレセプター2型 / インターフェロンαレセプター1型 / インターロイキン10 / 転移 / real time RT-PCR法 / インターフェロンαレセプタ / Cdc42 / Rac / 癌 / 腎 / FH遺伝子 / aerobic glycolysis / PTHrP / 精巣腫瘍 / 生存期間 / 進達度 / 異型度 / PTHrP遺伝子 / k-ras遺伝子 … More
Except Principal Investigator
carbachol / Rho / β-adrenoceptor / Rho-kinase / adrenergic / muscarinic / smooth muscle / bladder / 尿道 / 膀胱底部 / サブタイプ / Rho kinase / Y27632 / betaアドレナリン受容体 / 機能的収縮 / アドレナリン受容体 / ムスカリン受容体 / 排尿筋 / 抗ムスカリン薬 / G蛋白 / Rho-キナーゼ / β-アドレナリン受容体 / カルバコール / Rhoキナーゼ / アドレナリン / ムスカリン / 平滑筋 / 膀胱 Less
  • Research Projects

    (7 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (4 People)
  •  Molecular biological analysis of disorders of energy metabolism and mechanisms of Immune Escape in cancer in renal cell carcinomaPrincipal Investigator

    • Principal Investigator
      kamai takao
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Dokkyo Medical University
  •  Study of metabolic reprogramming and immune evasion in renal cell carcinomaPrincipal Investigator

    • Principal Investigator
      Kamai Takao
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Dokkyo Medical University
  •  Relationship between FH tumor-suppressor gene and aerobic glycolysis (Warburg effect)Principal Investigator

    • Principal Investigator
      Kamai Takao
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Dokkyo Medical University
  •  The role of interferon pathway in progression and metastasis in renal cell carcinomaPrincipal Investigator

    • Principal Investigator
      KAMAI Takao
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Dokkyo Medical University
  •  The role of autonomic nerve receptor subtypes and G-proteins for the cause of overactive bladder

    • Principal Investigator
      YAMANISHI Tomonori
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Dokkyo University School of Medicine
  •  The study of roles of Rho family GTPase in progression and metastasis of renal cell cancerPrincipal Investigator

    • Principal Investigator
      KAMAI Takao
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Dokkyo University School of Medicine (32203)
  •  腎細胞癌の進展・転移における癌関連遺伝子の発現の検討Principal Investigator

    • Principal Investigator
      釜井 隆男
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Urology
    • Research Institution
      Dokkyo Medical University

All 2022 2019 2018 2016 2004

All Journal Article Presentation

  • [Journal Article] Increased expression of Nrf2 and elevated glucose uptake in pheochromocytoma and paraganglioma with SDHB gene mutation2022

    • Author(s)
      Kamai Takao、Murakami Satoshi、Arai Kyoko、Nishihara Daisaku、Uematsu Toshitaka、Ishida Kazuyuki、Kijima Toshiki
    • Journal Title

      BMC Cancer

      Volume: 22 Issue: 1 Pages: 289-289

    • DOI

      10.1186/s12885-022-09415-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09534, KAKENHI-PROJECT-20K09546
  • [Journal Article] Association of Nrf2 expression and mutation with Weiss and Helsinki scores in adrenocortical carcinoma2022

    • Author(s)
      Kamai Takao、Murakami Satoshi、Arai Kyoko、Ishida Kazuyuki、Kijima Toshiki
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 7 Pages: 2368-2377

    • DOI

      10.1111/cas.15379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09534, KAKENHI-PROJECT-20K09546
  • [Journal Article] Circulating tumor cells and cell-free tumor DNA analyses in urothelial cancer using the LiquidBiopsy platform2022

    • Author(s)
      Kobayashi Minoru、Abe Hideyuki、Arai Kyoko、Murakami Satoshi、Kamai Takao
    • Journal Title

      Current Urology

      Volume: 16 Issue: 2 Pages: 99-106

    • DOI

      10.1097/cu9.0000000000000091

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K09546
  • [Journal Article] Nrf2 gene mutation and single nucleotide polymorphism rs6721961 of the Nrf2 promoter region in renal cell cancer2019

    • Author(s)
      Yamaguchi Yoshiyuki、Kamai Takao、Higashi Satoru、Murakami Satoshi、Arai Kyoko、Shirataki Hiromichi、Yoshida Ken-Ichiro
    • Journal Title

      BMC Cancer

      Volume: 19 Issue: 1 Pages: 1137-1137

    • DOI

      10.1186/s12885-019-6347-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17045, KAKENHI-PROJECT-17K11156
  • [Journal Article] Germline polymorphism of interferon-lambda3 is clinically associated with progression of renal cell carcinoma2018

    • Author(s)
      Nukui A, Yanai Y, Tsuzuki T, Abe H, Arai K, Yoshida K, Kamai T
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 3 Pages: 4188-4199

    • DOI

      10.18632/oncotarget.23683

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11156
  • [Journal Article] Clinically significant association of elevated expression of nuclear factor E2-related factor 2 expression with higher glucose uptake and progression of upper urinary tract cancer.2018

    • Author(s)
      Nukui A, Narimatsu T, Kambara T, Abe H, Sakamoto S, Yoshida KI, Kamai T.
    • Journal Title

      BMC Cancer

      Volume: 2018 Issue: 1 Pages: 493-493

    • DOI

      10.1186/s12885-018-4427-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11156
  • [Journal Article] Increased Nrf2 expression by renal cell carcinoma is associated with postoperative chronic kidney disease and an unfavorable prognosis.2018

    • Author(s)
      Yuki H, Kamai T, Murakami S, Higashi S, Narimatsu T, Kambara T, Betsunoh H, Abe H, Arai K, Shirataki H, Yoshida KI.
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 47 Pages: 28351-28363

    • DOI

      10.18632/oncotarget.25322

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11156
  • [Journal Article] Higher preoperative serum levels of PD-L1 and B7-H4 are associated with invasive and metastatic potential and predictable for poor response to VEGF-targeted therapy and unfavorable prognosis of renal cell carcinoma2016

    • Author(s)
      Takehiko Fukuda, Takao Kamai, Akinori Masuda, Akinori Nukui, Hideyuki Abe, Kyoko Arai, Ken-Ichiro Yoshida
    • Journal Title

      Cancer Medicine

      Volume: 5(8) Issue: 8 Pages: 1810-1820

    • DOI

      10.1002/cam4.754

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462426
  • [Journal Article] Radical nephrectomy and regional lymph node dissection for locally advanced type 2 papillary renal cell carcinoma in an at-risk individual from a family with hereditary leiomyomatosis and renal cell cancer: a case report2016

    • Author(s)
      Takao Kamai, Hideyuki Abe, Kyoko Arai, Satoshi Murakami, Setsu Sakamoto, Yasushi Kaji
    • Journal Title

      BMC Cancer

      Volume: 16 Issue: 1 Pages: 232-232

    • DOI

      10.1186/s12885-016-2272-7

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462426
  • [Journal Article] Overexpression of RhoA, Rac1, and Cdc42 GTPases is associated with progression in testicular cancer.2004

    • Author(s)
      Kamai T et al.
    • Journal Title

      Clinical Cancer Research 10

      Pages: 4799-4805

    • Data Source
      KAKENHI-PROJECT-14571516
  • [Journal Article] Single-blind, randomized controlled study of the clinical and urodynamic effects of an alpha-blocker (naftopidil) and phytotherapy (eviprostat) in the treatment of benign prostatic hyperplasia.2004

    • Author(s)
      Yamanishi T, Yasuda K, Kamai T, Tsujii T, Sakakibara R, Uchiyama T, Yoshida KI.
    • Journal Title

      Int J Urol. Jul;11

      Pages: 501-509

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571516
  • [Presentation] 部尿路上皮癌におけるPD-L1およびFAPの発現と臨床的/病理学的因子との関連2022

    • Author(s)
      西原大策、木島敏樹、貫井昭徳、新井京子、釜井隆男:
    • Organizer
      第99回日本泌尿器科学会栃木地方会
    • Data Source
      KAKENHI-PROJECT-20K09546
  • 1.  YAMANISHI Tomonori (90220425)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  辻井 俊彦 (90217307)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  木島 敏樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 4.  東 覚
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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