Kinoshita Ayae 木下彩栄

… Alternative Names

KINOSHITA Ayae 木下彩栄

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Researcher Number	80321610
Other IDs
Affiliation (Current)	2023: 京都大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2023: 京都大学, 医学研究科, 教授 2013: 京都大学, 医学研究科, 教授 2011 – 2013: 京都大学, 医学(系)研究科(研究院), 教授 2007 – 2011: Kyoto University, Graduate School of Medicine, Assistant Professor 2010: Kyoto University, 大学院・医学研究科, 教授 … More 2005 – 2006: Kyoto University, Faculty of Medicine, Professor, 医学部, 教授 2004: 京都大学, 医学研究科, 研究員(科学技術振興)(常勤形態) 2001: 岡崎共同研究機構, 生理学研究所, 助手 1999 – 2001: Natl. Inst. Physiol. Sci., Research Associ., 生理学研究所, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Nerve anatomy/Neuropathology / Basic Section 52020:Neurology-related / Basic Section 59010:Rehabilitation science-related / Neurology / Community health/Gerontological nurisng / Neurology Except Principal Investigator Neurology / Community health/Gerontological nurisng / Basic Section 58060:Clinical nursing-related … More / Basic Section 09030:Childhood and nursery/pre-school education-related / Basic Section 58080:Gerontological nursing and community health nursing-related / Intelligent informatics / Neuroscience in general / Nerve anatomy/Neuropathology Less
Keywords	Principal Investigator アルツハイマー病 / プレセニリン / 認知症 / N-cadherin / シナプス / カドヘリン / シグナル伝達 / リン酸化 / FRET / BACE … More / アミロイド / γセクレターゼ / マイオカイン / 運動 / Alzheimer's disease / カテニン / シナプス可塑性 / 情報伝達 / 筋 / irisin / FNDC5 / 老人斑 / アミロイドβ / アルツアイマー病 / catenin / cadherin / signal transduction / phosphorylation / synapse / presenilin / gamma-secretase / amyloid beta / 転写 / 核移行 / γ-セクレターゼ / グリア細胞 / カルシウム / タウ / 神経原線維変化 / βアミロイド / IGF-BP / 炎症性サイトカイン / アストロサイト / スカイプ / テレビ電話 / 在宅支援 / テレビカメラ / Skype / 在宅介護 / IT / インスリン / 神経変性 / 老化 / GSK3β / βセクレターゼ / 老人班 / セクレターゼ / 自己抗体 / 小脳失調 / ホジキン病 / mGluR1 / グルタミン酸受容体 … More Except Principal Investigator 認知症 / フレイル / サルコペニア / cerebellum / glutamate / 小脳 / グルタミン酸受容体 / アルツハイマー病 / 痴呆 / 看護学 / 医療・福祉 / 腸内細菌叢 / SLE / 高齢者 / 神経心理学 / 女子 / 思春期 / MRI / カヘキシア / ロコモティブシンドローム / 関節リウマチ / 脳、神経 / 神経分子病態学 / アルツハイマー型認知症 / 医療情報学 / 自然言語処理 / moto learning / globus palllidus / blockig antibody / nGluR1 / 運動学習 / 淡蒼球 / 阻害抗体 / mGluR1 / immunocytochemistry / electron microscopy / receptor / metabotropic / GABAB / 形態学 / 受容体 / GABA / グルタミン酸 / 抑制性シナプス / 興奮性シナプス / 免疫組織化学 / 電子顕微鏡 / GABAB受容体 / アミロイド前駆体蛋白 / 国際情報交流（アメリカ） / 神経変性疾患 / 脳・神経 / 神経科学 / 介護負担 / 家族 / スカイプ / IT / 在宅支援 Less

全身性エリテマトーデス患者におけるサルコペニア有病割合と関連因子に関する研究
- Principal Investigator
  
  鳥井美江
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58060:Clinical nursing-related
- Research Institution
  Kyoto University
女性の生涯発達に関連した脳機能基盤の解明
- Principal Investigator
  
  日吉和子
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 09030:Childhood and nursery/pre-school education-related
- Research Institution
  Nagoya City University
認知症患者における認知機能と運動機能・運動関連マイオカインとの関連の解析Principal Investigator
- Principal Investigator
  
  木下彩栄
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyoto University
Investigation of risk factors for sarcopenia in patients with rheumatoid arthritis and establishment of a biochemical evaluation method.
- Principal Investigator
  
  Mie Torii
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58080:Gerontological nursing and community health nursing-related
- Research Institution
  Kyoto University
Preventitive Effect of amyloid beta production in Alzheimer's disease by myokines after exercisePrincipal Investigator
- Principal Investigator
  
  Kinoshita Ayae
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kyoto University
Using Natural Language Processing of Patient Short Narratives to Detect Cognitive Impairment
- Principal Investigator
  
  ARAMAKI Eiji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Intelligent informatics
- Research Institution
  Nara Institute of Science and Technology
The examination of AD pathology from the perspective of the astrocyte-neuron interaction: the participation of IGFBP-3 released by astrocytes.
- Principal Investigator
  
  Uemura Kengo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University
グリア細胞内のカルシウム調節破綻を介した神経変性過程の解明Principal Investigator
- Principal Investigator
  
  木下彩栄
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
abc
- Principal Investigator
  
  UEMURA Kengo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University
The development of the bi-directional support system for the homecare patients by using SkypePrincipal Investigator
- Principal Investigator
  
  KINOSHITA Ayae
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Community health/Gerontological nurisng
- Research Institution
  Kyoto University
The study of the communication system for elderly patients and their caregivers with ICT tools (webcam and Blog)
- Principal Investigator
  
  HORI Miyako
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Community health/Gerontological nurisng
- Research Institution
  Nagoya University
Analysis of the mechanism of pathological synaptic alterations in Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  KINOSHITA Ayae
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyoto University
The support system for dementia patient with bidirectional IT communications
- Principal Investigator
  
  KUBOTA Masakazu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Community health/Gerontological nurisng
- Research Institution
  Kyoto University
プレセニリン機能障害によるシナプス制御機構の破綻Principal Investigator
- Principal Investigator
  
  木下彩栄
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
プレセニリンを介したカドヘリンーカテニン複合体とシグナル伝達のクロストークPrincipal Investigator
- Principal Investigator
  
  木下彩栄
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Investigation of the synaptic dissociation mechanismPrincipal Investigator
- Principal Investigator
  
  KINOSHITA Ayae
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyoto University
アルツハイマー病関連蛋白における細胞内情報伝達制御機構の解明Principal Investigator
- Principal Investigator
  
  木下彩栄
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
FRETを利用したアルツハイマー病アミロイドβ蛋白の産生部位の同定の試みPrincipal Investigator
- Principal Investigator
  
  木下彩栄
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
A novel transcriptional regulation mechanism regulated by Alzheimer-related proteins.Principal Investigator
- Principal Investigator
  
  KINOSHITA Ayae
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University
抗神経抗体の神経機能阻害によるヒト脳疾患の病態の解明Principal Investigator
- Principal Investigator
  
  木下彩栄
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurology
- Research Institution
  Okazaki National Research Institutes
Mechanism of mGluR1-mediated regulation of brain function as examined with blocking autantibodies
- Principal Investigator
  
  SHIGEMATO Ryuichi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Natiomal Institute for Physiological Scienes
Morphological analysis of interaction between excitatory and inhibitory synapses
- Principal Investigator
  
  SIGEMOTO Ryuichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  National Institute for Physiological Sciences
  Kyoto University

[Book] わかりやすい内科学2014
- Author(s)
  木下彩栄　ら
- Total Pages
  992
- Publisher
  文光堂
- Data Source
  KAKENHI-PUBLICLY-24111524
[Book] 認知症ハンドブック2013
- Author(s)
  木下彩栄　ら
- Total Pages
  907
- Publisher
  医学書院
- Data Source
  KAKENHI-PUBLICLY-24111524
[Book] 老年性認知症「外来診療ハンディガイド」2010
- Author(s)
  木下彩栄
- Publisher
  日経メディカル
- Data Source
  KAKENHI-PROJECT-20300124
[Book] 老年性認知症「ガイドライン外来診療2009」2009
- Author(s)
  木下彩栄
- Publisher
  日経メディカル
- Data Source
  KAKENHI-PROJECT-20300124
[Book] 神経変性疾患のサイエンス2007
- Author(s)
  木下彩栄, 他 (高橋良輔編)
- Total Pages
  247
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-18023021
[Book] 神経変性疾患のサイエンス2007
- Author(s)
  木下彩栄, 他 (高橋良輔編)
- Total Pages
  247
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-18059019
[Book] 神経変性疾患のサイエンス2007
- Author(s)
  木下彩栄, 他 (高橋良輔編)
- Total Pages
  247
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-18500263
[Book] 神経変性疾患のサイエンス2007
- Author(s)
  木下彩栄他(高橋良輔編)
- Total Pages
  247
- Publisher
  南山堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] Analysis of the Clock-Reading Ability in Patients with Cognitive Impairment: Comparison of Analog Clocks and Digital Clocks2022
- Author(s)
  Shimosaka M, Nishimoto H, Kinoshita A
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: - Issue: 3 Pages: 1151-1165
- DOI
  10.3233/jad-215471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11415
[Journal Article] AR/VR高次脳機能リハビリテーション2022
- Author(s)
  岡橋さやか、木下彩栄
- Journal Title
  
  総合リハビリテーション
  
  Volume: 50 Pages: 367-374
- Data Source
  KAKENHI-PROJECT-19K11415
[Journal Article] Reminiscence therapy using virtual reality technology affects cognitive function and subjective well-being in older adults with dementia. Cogent Psychology2021
- Author(s)
  Tominari M, Uozumi R, Becker C, Kinoshita A
- Journal Title
  
  Cogent Psychology
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11415
[Journal Article] Dynamic theta/beta ratio of clinical EEG in Alzheimer's disease.2021
- Author(s)
  Miao Y, Jurica P, Struzik ZR, Hitomi T, Kinoshita A, Takahara Y, Ogawa K, Hasegawa H, Cichocki A
- Journal Title
  
  Journal of Neuroscience Methods
  
  Volume: 15 Pages: 109219-109219
- DOI
  10.1016/j.jneumeth.2021.109219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11415
[Journal Article] Perceptions and behaviours related to COVID-19 in patients with rheumatoid arthritis: a cross-sectional study2021
- Author(s)
  Itaya Takahiro、Torii Mie、Hashimoto Motomu、Jindai Kazuaki、Yamamoto Wataru、Tanigawa Kyosuke、Urai Yuki、Kinoshita Ayae、Nin Kazuko、Watanabe Ryu、Murata Koichi、Murakami Kosaku、Tanaka Masao、Ito Hiromu、Matsuda Shuichi、Morinobu Akio
- Journal Title
  
  Clinical Rheumatology
  
  Volume: 41 Issue: 1 Pages: 45-51
- DOI
  10.1007/s10067-021-05840-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11165
[Journal Article] Prevalence of anxiety and depression in patients with rheumatoid arthritis before and during the COVID-19 pandemic2021
- Author(s)
  Itaya T, Torii M, Hashimoto M, Tanigawa K, Urai Y, Kinoshita A, Nin K, Jindai K, watanabe R, Murata K, Murakami K, Tanaka M, Ito H, Matsuda S, Morinobu A
- Journal Title
  
  Reumatology
  
  Volume: 60（4） Issue: 4 Pages: 2023-2024
- DOI
  10.1093/rheumatology/keab065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11165, KAKENHI-PROJECT-20K17418, KAKENHI-PROJECT-21K09298
[Journal Article] 音声発話による認知症スクリーニング技術の開発 - 感情表現辞書を用いた発話内容の質的分析2018
- Author(s)
  柴田大作，若宮翔子，木下彩栄，荒牧英治
- Journal Title
  
  医療情報学
  
  Volume: 37(6) Pages: 303-312
- NAID
  130007592888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K12489
[Journal Article] Idea density in Japanese for the early detection of dementia based on narrative2018
- Author(s)
  Shibata D, Ito K, Nagai H, Okahisa T, Kinoshita A, Aramaki E
- Journal Title
  
  PLoS One
  
  Volume: 13 (2) Issue: 12 Pages: e0208418-e0208418
- DOI
  10.1371/journal.pone.0208418
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-16H06395, KAKENHI-PLANNED-16H06399, KAKENHI-PROJECT-16K12489
[Journal Article] The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer's disease.2015
- Author(s)
  Watanabe K, Uemura K, Asada M, Maesako M, Akiyama H, Shimohama S, Takahashi R, Kinoshita A.
- Journal Title
  
  Mol Brain
  
  Volume: 4;8(1) Issue: 1 Pages: 82-82
- DOI
  10.1186/s13041-015-0174-2
- NAID
  120005708017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461270, KAKENHI-PLANNED-23111002
[Journal Article] High Fat Diet Enhances β-Site Cleavage of Amyloid Precursor Protein (APP) via Promoting β-Site APP Cleaving Enzyme 1/Adaptor Protein 2/Clathrin Complex Formation.2015
- Author(s)
  Maesako M, Uemura M, Tashiro Y, Sasaki K, Watanabe K, Noda Y, Ueda K, Asada-Utsugi M, Kubota M, Okawa K, Ihara M, Shimohama S, Uemura K, Kinoshita A.
- Journal Title
  
  PLoS One.
  
  Volume: 10(9) Issue: 9 Pages: e0131199-e0131199
- DOI
  10.1371/journal.pone.0131199
- NAID
  120005947169
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461270
[Journal Article] Idiopathic Normal Pressure Hydrocephalus has a Different Cerebrospinal Fluid Biomarker Profile from Alzheimer's Disease2014
- Author(s)
  Naoto Jingami, Megumi Asada-Utsugi, Kengo Uemura, Rio Noto, Makio Takahashi, Akihiko Ozaki, Takeshi Kihara, Takashi Kageyama, Ryosuke Takahashi, Shun Shimohama, Ayae Kinoshita.
- Journal Title
  
  Jounral of Alzheimer's Disease
  
  Volume: 126（４） Issue: 1 Pages: 675-81
- DOI
  10.3233/jad-142622
- NAID
  120005593597
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-23111001, KAKENHI-PROJECT-26461270, KAKENHI-PLANNED-23111002
[Journal Article] Copper enhances APP dimerization and promotes Abeta production2013
- Author(s)
  Noda Y, Asada M, Kubota M, Maesako M, Watanabe K, Uemura M, Kihara T, Shimohama S, Takahashi R, Kinoshita A, Uemura K
- Journal Title
  
  Neuroscience Letters
  
  Volume: 547 Pages: 10-15
- DOI
  10.1016/j.neulet.2013.04.057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22390180, KAKENHI-ORGANIZER-23111001, KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23659460, KAKENHI-PUBLICLY-24111524
[Journal Article] Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes2013
- Author(s)
  7. Ly PT, Wu Y, Zou H, Wang R, Zhou W, Kinoshita A, Zhang M, Yang Y, Cai F, Woodgett J, *Song W
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 123 Issue: 1 Pages: 224-235
- DOI
  10.1172/jci64516
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24111524
[Journal Article] Copper enhances APP dimerization and promotes Aβproduction2013
- Author(s)
  Noda Y, Asada M, Kubota M, Maesako M, Watanabe K, Uemura M, Kihara T, Shimohama S, Takahashi R, Kinoshita A, Uemura K
- Journal Title
  
  Neurosci Lett
  
  Volume: 547 Pages: 10-5
- Data Source
  KAKENHI-PROJECT-23591243
[Journal Article] Copper enhances APP dimerization and promotes Aβ production.2013
- Author(s)
  Noda Y, Asada M, Kubota M, Maesako M, Watanabe K, Uemura M, Kihara T, Shimohama S, Takahashi R, Kinoshita A, Uemura K.
- Journal Title
  
  Neurosci Lett
  
  Volume: 547 Pages: 10-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591243
[Journal Article] Continuation of exercise is necessary to inhibit high fat diet-inducde β-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice.2013
- Author(s)
  Masato Maesako, Kengo Uemura, Ayana Iwata, Masakazu Kubota, Kiwamu Watanabe, Maiko Uemura, Yasuha Noda, Megumi Asada-Utsugi, Takeshi Kihara, Ryosuke Takahashi, Shun Shimohama and Ayae Kinoshita.
- Journal Title
  
  PLos One
  
  Volume: 8 Issue: 9 Pages: e72796-e72796
- DOI
  10.1371/journal.pone.0072796
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J00221, KAKENHI-PROJECT-22390180, KAKENHI-ORGANIZER-23111001, KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23659460, KAKENHI-PUBLICLY-24111524
[Journal Article] Videophone-based multimodal home telecare support system for patients with diabetes.2013
- Author(s)
  Kubota M, Hosoda K, Eguchi K, Furuya A, Nishijima Y, Nakao K, Kinoshita A
- Journal Title
  
  Diabetology International
  
  Volume: 4 Pages: 52-59
- NAID
  10030925834
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24111524
[Journal Article] Environmental enrichment ameliorated high-fat diet-induced Aβ deposition and memory deficit in APP transgenic mice.2012
- Author(s)
  Maesako M, Uemura K, Kubota M, Kuzuya A, Sasaki K, Asada M, Watanabe K, Hayashida N, Ihara M, Ito H, Shimohama S, Kihara T, Kinoshita A.
- Journal Title
  
  Neurobiol Aging
  
  Volume: 33
- NAID
  120003988394
- Data Source
  KAKENHI-PROJECT-23591243
[Journal Article] Environmental enrichment ameliorated high fat diet-induced Aβdeposition and memory deficit in APP transgenic mice2012
- Author(s)
  Maesako M, Uemura K, Kubota M, Kuzuya A, Sasaki K, Asada M, Watanabe K, Hayashida N, Ihara M, Ito H, ShimohamaS, Kihara T, Kinoshita A
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 33 Issue: 5 Pages: 11-23
- DOI
  10.1016/j.neurobiolaging.2011.10.028
- NAID
  120003988394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23591243, KAKENHI-PROJECT-23650182, KAKENHI-PUBLICLY-24111524
[Journal Article] Gain of function by phosphorylation in Presenilin 1-mediated regulation of insulin signaling2012
- Author(s)
  Maesako M, Uemura K, Kuzuya A, Sasaki K, Asada M, Watanabe K, Ando K, Kubota M, Akiyama H, Takahashi R, Kihara T, Shimohama S, Kinoshita A.
- Journal Title
  
  J Neurochem
  
  Volume: 121 Issue: 6 Pages: 964-973
- DOI
  10.1111/j.1471-4159.2012.07741.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529, KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23591243, KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111002, KAKENHI-PUBLICLY-24111524
[Journal Article] Gain of function by phosphorylation in Presenilin 1-mediated regulation of insulin signaling2012
- Author(s)
  Maesako M, Uemura K, Kuzuya A, Sasaki K, Asada M, Watanabe K, Ando K, Kubota M, Akiyama H, Takahashi R, Kihara T, Shimohama S, Kinoshita A
- Journal Title
  
  J Neurochem
  
  Volume: 121(6) Pages: 964-73
- Data Source
  KAKENHI-PROJECT-23591243
[Journal Article] Exercise Is More Effective than Diet Control in Preventing High Fat Diet-induced β-Amyloid Deposition and Memory Deficit in Amyloid Precursor Protein Transgenic Mice.2012
- Author(s)
  Maesako M
- Journal Title
  
  J Biol Chem.
  
  Volume: 287 Issue: 27 Pages: 23024-23033
- DOI
  10.1074/jbc.m112.367011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23591243, KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111002, KAKENHI-PUBLICLY-24111524
[Journal Article] Effect of glycogen synthase kinase 3 β-mediated presenilin 1 phosphorylation on amyloid β production is negatively regulated by insulin receptor cleavage2011
- Author(s)
  Maesako M, Uemura K, Kubota M, Hiyoshi K, Ando K, Kuzuya A, Kihara T, Asada M, Akiyama H, Kinoshita A
- Journal Title
  
  Neuroscience
  
  Volume: 177 Pages: 298-307
- NAID
  120002970866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] N-cadherin enhances APP dimerization at the extracellular domain and modulates Aβproduction2011
- Author(s)
  Asada-Utsugi M, Uemura K, Noda Y, Kuzuya A, Maesako M, Ando K, Kubota M, Watanabe K, Takahashi M, Kihara T, Shimohama S, Takahashi R, Berezovska O, Kinoshita A
- Journal Title
  
  J Neurochem
  
  Volume: 119(2) Pages: 354-63
- Data Source
  KAKENHI-PROJECT-23591243
[Journal Article] N-cadherin regulates p38 MAPK signaling via association with JNK-associated leucine zipper protein : implications for neurodegeneration in Alzheimer disease2011
- Author(s)
  Ando K, Uemura K, Kuzuya A, Maesako M, Asada-Utsugi M, Kubota M, Aoyagi N, Yoshioka K, Okawa K, Inoue H, Kawamata J, Shimohama S, Arai T, Takahashi R, Kinoshita A
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 7619-7628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] テレビ電話を用いた定期的な介入が糖尿病患者の血糖コントロールに与える影響2011
- Author(s)
  久保田正和、細田公則、江口恭子、古家彩名、西嶋ゆき、中尾一和、木下彩栄
- Journal Title
  
  癌と化学療法
  
  Volume: 38 Pages: 97-99
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] N-cadherin regulates p38 MAPK signaling via association with JNK-associated leucine zipper protein : implications for neurodegeneration in Alzheimer disease2011
- Author(s)
  Ando K, Uemura K, Kuzuya A, Maesako M, Asada-Utsugi M, Kubota M, Aoyagi N, Yoshioka K, Okawa K, Inoue H, Kawamata J, Shimohama S, Arai T, Takahashi R, Kinoshita A
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 7619-7628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] Presenilin regulates insulin signaling viagamma-secretase independent mechanism2011
- Author(s)
  Maesako M, Uemura K, Kuzuya A, Sasaki K, Asada M, Watanabe K, Ando K, Kubota M, Kihara T, Ayae Kinoshita
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 25309-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] Effect of glycogen synthase kinase 3 β-mediated presenilin 1 phosphorylation on amyloid β production is negatively regulated by insulin receptor cleavage.2011
- Author(s)
  Maesako M, Uemura K, Kubota M, Hiyoshi K, Ando K, Kuzuya A, Kihara T, Asada M, Akiyama H, Kinoshita A
- Journal Title
  
  Neuroscience 177
  
  Pages: 298-307
- NAID
  120002970866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] N-cadherin enhances APP dimerization at the extracellular domain and modulates Aβ production.2011
- Author(s)
  Asada-Utsugi M, Uemura K, Noda Y, Kuzuya A, Maesako M, Ando K, Kubota M, Watanabe K, Takahashi M, Kihara T, Shimohama S, Takahashi R, Berezovska O, Kinoshita A.
- Journal Title
  
  J Neurochem.
  
  Volume: 119 Pages: 354-63
- Data Source
  KAKENHI-PROJECT-23591243
[Journal Article] Insightinto"synaptopathy"in Alzheimer' sdisease : From lifestyle to PS1/N-cadherininteraction.2011
- Author(s)
  Kuzuya A, Kinoshita A, Uemura K.
- Journal Title
  
  Alz Dis Res J
  
  Volume: 3 Pages: 47-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] Insight into "synaptopathy" in Alzheimer's disease2011
- Author(s)
  Kuzuya A, Uemura K, Kinoshita A
- Journal Title
  
  Journal of Alzheimer's Disease Research
  
  Volume: In press
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] Effect of glycogen synthase kinase 3 β-mediated presenilin 1 phosphorylation on amyloid β production is negatively regulated by insulin receptor cleavage2011
- Author(s)
  Maesako M, Uemura K, Kubota M, Hiyoshi K, Ando K, Kuzuya A, Kihara T, Asada M, Akiyama H, Kinoshita A
- Journal Title
  
  Neuroscience
  
  Volume: 177 Pages: 298-307
- NAID
  120002970866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] Insight into "synaptopathy" in Alzheimer's disease2011
- Author(s)
  Kuzuya A, Uemura K, Kinoshita A
- Journal Title
  
  Journal of Alzheimer's Disease Research
  
  Volume: (In press)
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] N-cadherin regulates p38 MAPK signaling via association with JNK-associated leucine zipper protein : implications for neurodegeneration in Alzheimer disease.2011
- Author(s)
  Ando K, Uemura K, Kuzuya A, Maesako M, Asada-Utsugi M, Kubota M, Aoyagi N, Yoshioka K, Okawa K, Inoue H, Kawamata J, Shimohama S, Arai T, Takahashi R, Kinoshita A
- Journal Title
  
  J Biol Chem 286
  
  Pages: 7619-7628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] N-cadherin regulates p38MAPK signaling via association with JNK-associated leucine zipper protein implications for neurodegeneration in Alzheimer disease2011
- Author(s)
  Ando K, Uemura K, Kuzuya A, Maesako M, Asada-Utsugi M, Kubota M, Aoyagi N, Yoshioka K, Okawa K, Inoue H, Kawamata J, Shimohama S, Arai T, Takahashi R, Kinoshita A.
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 7619-7628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] Effect of glycogensynthase kinase 3β-mediated presenilin 1phosphorylation on amyloidβproductionis negatively regulated by insulin receptor cleavage2011
- Author(s)
  Maesako M, Uemura K, Kubota M, HiyoshiK, Ando K, Kuzuya A, Kihara T, Asada M, Akiyama H, Kinoshita A.
- Journal Title
  
  Neuroscience
  
  Volume: 177 Pages: 298-307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] Presenilin regulates insulin signaling via a gamma-secretase-independent mechanism.2011
- Author(s)
  Maesako M, Uemura K, Kuzuya A, Sasaki K, Asada M, Watanabe K, Ando K, Kubota M, Kihara T, Kinoshita A.
- Journal Title
  
  J Biol Chem.
  
  Volume: 286 Pages: 25309-16
- Data Source
  KAKENHI-PROJECT-23591243
[Journal Article] 産学連携による共同研究の取り組みICT機器の在宅医療への応用2011
- Author(s)
  久保田正和、古家彩名、木下彩栄
- Journal Title
  
  健康科学
  
  Volume: 11(in press)
- NAID
  120004140450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] 産学連携による共同研究の取り組み & ICT機器の在宅医療への応用2011
- Author(s)
  久保田正和、古家彩名、木下彩栄
- Journal Title
  
  健康科学
  
  Volume: Vol7 Pages: 81-86
- NAID
  120004140450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] The cleavage of N-cadherin is essential for chondrocyte differenciaten.2010
- Author(s)
  Nakazora N, Matsumine A, Iino T, Hasegawa M, Kinoshita A, Uemura K, Niimi R, Uchida A, Sudo A.
- Journal Title
  
  Biochem Biophys Res Commun 400
  
  Pages: 493-499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] PI3K inhibition causes the accumulation of ubiquitinated presenilin 1 without affecting the proteasome activity.2010
- Author(s)
  Aoyagi N, Uemura K, Kuzuya A, Kihara T, Kawamata J, Shimohama S, Kinoshita A, Takahashi R.
- Journal Title
  
  Biochem Biophys Res Commun 391
  
  Pages: 1240-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] ブログを書くことが在宅認知症介護者に与えるストレス軽減効果2010
- Author(s)
  保利美也子、久保田正和、木下彩栄
- Journal Title
  
  癌と科学療法 37巻
  
  Pages: 192-194
- Data Source
  KAKENHI-PROJECT-21890105
[Journal Article] Insulin regulates Presenilin 1 localization via PI3K/Akt signaling.2010
- Author(s)
  Maesako M, Uemura K, Kubota M, Ando K, Kuzuya A, Kihara T, Kinoshita A
- Journal Title
  
  Nerosci Lett 483
  
  Pages: 157-161
- NAID
  120002484938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] Blogging is an effective way to reduce a stress for caregivers who are involved in caring dementia patients at home--the result from the questionnaire survey2010
- Author(s)
  Hori M, Kubota M, Kinoshita A
- Journal Title
  
  Gan to Kagaku Ryoho
  
  Volume: Supple 2 Pages: 192-194
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] Insulin regulates Presenilin1 localization viaPI3K/Akt signaling2010
- Author(s)
  Maesako M, Uemura K, Kubota M, Ando K, Kuzuya A, Kihara T, Kinoshita A.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 483 Pages: 157-161
- NAID
  120002484938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] The cleavage of N-cadherin is essential for chondrocyte differentiation2010
- Author(s)
  Nakazora S, Matsumine A, Iino T, Hasegawa M, Kinoshita A, Uemura K, Niimi R, Uchida A, Sudo A
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 400 Pages: 493-499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] The cleavage of N-cadherin is essential for chondrocyte differentiation2010
- Author(s)
  Nakazora S, Matsumine A, Iino T, Hasegawa M, Kinoshita A, Uemura K, Niimi R, Uchida A, Sudo A
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 400 Pages: 493-499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] Insulin regulates Presenilin 1 localization via PI3K/Akt signaling2010
- Author(s)
  Maesako M, Uemura K, Kubota M, Ando K, Kuzuya A, Asada M, Kihara T, Kinoshita A
- Journal Title
  
  Neuroscience Letters
  
  Volume: 483 Pages: 157-161
- NAID
  120002484938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] Insulin regulates Presenilin 1 localization via PI3K/Akt signaling2010
- Author(s)
  Maesako M, Uemura K, Kubota M, Ando K, Kuzuya A, Asada M, Kihara T, Kinoshita A
- Journal Title
  
  Neuroscience Letters
  
  Volume: 483 Pages: 157-161
- NAID
  120002484938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] Blogging is an effective way to reduce a stress for caregivers who are involvred in caring dementia patients at home-the result from the questionnaire survey2010
- Author(s)
  Hori M, Kubota M, Kinoshita A
- Journal Title
  
  Gan to Kagaku Ryoho
  
  Volume: Supple 2 Pages: 192-194
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] 在宅認知症高齢者とその家族介護者に対するテレビ電話を用いたコミュニケーションの有効性2010
- Author(s)
  保利美也子、久保田正和、安藤功一、木原武士、高橋良輔、木下彩栄
- Journal Title
  
  癌と化学療法 36
  
  Pages: 36-38
- Data Source
  KAKENHI-PROJECT-21890105
[Journal Article] 在宅認知症高齢者とその家族介護者に対するテレビ電話システムを用いたコミュニケーションの有効性2009
- Author(s)
  保利美也子, 久保田正和, 安藤功一, 木原武士, 高橋良輔, 木下彩栄
- Journal Title
  
  癌と化学療法 36(Suppl)
  
  Pages: 36-38
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] Chronic cerebral hypoperfusion accelerates amyloid beta deposition in APPSwedish transgenic mouse2009
- Author(s)
  Kitaguchi H, Tomimoto H, Ihara M, Shibata M, Uemura K, Kalaria RN, Kihara T, Asada-Utsugi M, Kinoshita A, Takahashi R
- Journal Title
  
  Brain Research 1294
  
  Pages: 202-210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] N-cadherin-based adhesion enhances Abeta release and decreased Abet a42/40 ratio2009
- Author(s)
  Uemura K, Lill CM, Banks M, Aoyagi N, Ando K, Kubota M, Kihara T, Nishimoto T, Sugimoto H, Takahashi R, Hyman BT, Shimohama S, Kinoshita A
- Journal Title
  
  Journal of Neurochemistry 156
  
  Pages: 350-360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] Cronic cerebral hypoperfusion accelerates amyloid β deposition in APPSweInd transgenic mouse.2009
- Author(s)
  Kitaguchi H, Tomimoto H, Ihara M, Shibata M, Uemura K, Kalaria RN, Kihara T, Asada-Utsugi M, Kinoshita A, Takahashi R.
- Journal Title
  
  Brain Research 1294
  
  Pages: 202-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] N-cadherin-based adhesion enhances Abeta release and decreased Abeta42/40 ratio2009
- Author(s)
  Uemura K, Lill CM, Banks M, Aoyagi N, Ando K, 久保田正和, 木原武士, Nishimoto T, Sugimoto H, 高橋良輔, Hyman BT, Shimohama S, 木下彩栄
- Journal Title
  
  Journal of Neurochemistry 156
  
  Pages: 350-360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] N-cadherin-based adhesion enhances Aβ release and decrerased Aβ42/40 ratio.2009
- Author(s)
  Uemura, K, Lill CM, Banks M, Aoyagi N, Ando, K., Kubota M, Kihara T, Nishimoto T, Sugimoto H, Takahashi R, Hyman BT, Shimohama S, Berezovska O, Kinoshita A
- Journal Title
  
  J Neurochem 156
  
  Pages: 350-360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] 在宅認知症高齢者とその家族介護者に対するテレビ電話システムを用いたコミュニケーションの有効性2009
- Author(s)
  保利美也子、久保田正和、安藤功一、木原武士、高橋良輔、木下彩栄
- Journal Title
  
  癌と化学療法
  
  Volume: 36 Pages: 36-38
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] N-cadherin-based adhesion enhances Aβrelease and decrerased Aβ42/40 ratio2009
- Author(s)
  Uemura K, Lill CM, Banks M, Aoyagi N, Ando, K., Kubota M, Kihara T, Nishimoto T, Sugimoto H, Takahashi R, Hyman BT, Shimohama S, Berezovska O, Kinoshita, A
- Journal Title
  
  J Neurochem
  
  Volume: 156 Pages: 350-360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] 在宅認知症高齢者とその家族介護者に対するテレビ電話システムを用いたコミュニケーションの有効性2009
- Author(s)
  保利美也子, 久保田正和, 安藤功一, 木原武士, 高橋良輔, 木下彩栄
- Journal Title
  
  癌と化学療法 36(Suppl)
  
  Pages: 36-38
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article]2009
- Author(s)
  木下彩栄, 他
- Journal Title
  
  ガイドライン外来診療 2009(日経メディカル開発)
  
  Pages: 395-402
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article]2009
- Author(s)
  木下彩栄, 他
- Journal Title
  
  外来診療ハンディガイド(日経メディカル開発)
  
  Pages: 200-203
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] Chronic cerebral hypoperfusion accelerates amyloid beta deposition in APPSwedish transgenic mouse2009
- Author(s)
  Kitaguchi H, Tomimoto H, Ihara M, Shibata M, Uemura K, Kalaria RN, 木原武士, Asada-Utsugi M, 木下彩栄, 高橋良輔
- Journal Title
  
  Brain Research 1294
  
  Pages: 202-210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article]2009
- Author(s)
  木下彩栄, 他
- Journal Title
  
  外来診療ハンディガイド(日経メディカル開発)
  
  Pages: 200-203
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article]2009
- Author(s)
  木下彩栄, 他
- Journal Title
  
  ガイドライン外来診療 2009(日経メディカル開発)
  
  Pages: 395-402
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] γセクレターゼとシナプス機能2008
- Author(s)
  穏村健吾、安藤功一、久保田正和、木下彩栄
- Journal Title
  
  Cognition and Dementia 7
  
  Pages: 46-54
- Data Source
  KAKENHI-PROJECT-18023021
[Journal Article] γセクレターゼとシナプス機能2008
- Author(s)
  植村健吾、安藤功一、久保田正和、木下彩栄
- Journal Title
  
  Cognition and Dementia 7
  
  Pages: 46-54
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] Skypeとwebcameraを利用した在宅認知症患者とその家族への支援2008
- Author(s)
  保利美也子、久保田正和、木下彩栄
- Journal Title
  
  癌と化学療法 35
  
  Pages: 46-47
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] Gamma-secretase and synaptic function2008
- Author(s)
  Kengo, Uemura, Koichi, Ando, Masakazu, Kubota, Ayae, Kinoshita
- Journal Title
  
  Cognition and Dementia 7
  
  Pages: 46-54
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] γセクレターゼとシナプス機能2008
- Author(s)
  植村健吾、安藤功一、久保田正和、木下彩栄
- Journal Title
  
  Cognition and Dementia 7
  
  Pages: 46-54
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] γセクレターゼとシナプス機能2008
- Author(s)
  植村健吾、安藤功一、久保田正和、木下彩栄
- Journal Title
  
  Cognition and Dementia 7
  
  Pages: 46-54
- Data Source
  KAKENHI-PROJECT-18059019
[Journal Article] スカイプとウェブカメラを使用した在宅認知症患者とその介護者への支援2008
- Author(s)
  保利美也子、久保田正和、木下彩栄
- Journal Title
  
  癌と化学療法 35巻
  
  Pages: 43-45
- Data Source
  KAKENHI-PROJECT-19890116
[Journal Article] スカイプとWebカメラを使用した在宅認知症患者とその介護者への支援2008
- Author(s)
  保利美也子, 久保田正和, 木下彩栄
- Journal Title
  
  癌と化学療法 35
  
  Pages: 43-45
- Data Source
  KAKENHI-PROJECT-19890116
[Journal Article] GSK3beta activity modifies the localization and function of presenilin12007
- Author(s)
  Uemura, K., Kuzuya, A., Shimozono, Y., Aoyagi, N., Ando, K., Shimohama, S., Kinoshita, A
- Journal Title
  
  Journal of Biological Chemistry 282
  
  Pages: 15823-32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] Amyloid beta inhibits ectodomain shedding of N-cadherinvia down-regulation of cell-surface NMDA receptor.2007
- Author(s)
  Uemura, K., Kuzuya, A., Aoyagi, N., Ando, K., Shimozono, Y., Ninomiya, H., Shimohama, S., & Kinoshita, A.
- Journal Title
  
  Neuroscience 145
  
  Pages: 5-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] GSK3beta activity modifies the localization and function of presenilinl.2007
- Author(s)
  Uemura K., Kuzuya A., Shimozono Y., Aoyagi N., Ando K., Shimohama S., & Kinoshita A.
- Journal Title
  
  Journal of Biological Chemistry 282
  
  Pages: 15823-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023021
[Journal Article] Amyloid beta inhibits ectodomain shedding of N-cadherinvia down-regulation of cell-surface NMDA receptor.2007
- Author(s)
  Uemura, K., Kuzuya, A., Aoyagi, N., Ando, K., Shimozono, Y., Ninomiya, H., Shimohama, S., & Kinoshita, A.
- Journal Title
  
  Neuroscience 145
  
  Pages: 510-510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023021
[Journal Article] Amyloid beta inhibits ectodomain shedding of N-cadherin via down-regulation of cell-surface NMDA receptor.2007
- Author(s)
  Uemura K., Kuzuya, A., Aoyagi, N., Ando, K., Shimozono, Y., Ninomiya, H., Shimohama, S., Kinoshita, A.
- Journal Title
  
  Neuroscience 145
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] Amyloid beta inhibits ectodomain shedding of N-cadherin via down-regulation of cell-surface NMDA receptor.2007
- Author(s)
  Uemura, K., Kuzuya, A., Aoyagi, N., Ando, K., Shimozono, Y., Ninomiya, H., Shimohama, S., & Kinoshita, A.
- Journal Title
  
  Neuroscience 145
  
  Pages: 5-10
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] GSK3beta activity modifies the localization and function of presenilinl.2007
- Author(s)
  Uemura K., Kuzuya A., Shimozono Y., Aoyagi N., Ando K., Shimohama S., & Kinoshita A.
- Journal Title
  
  Journal of Biological Chemistry 282
  
  Pages: 15823-32
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] Amyloid beta inhibits ectodomain shedding of N-cadherin via down-regulation of cell-surface NMDA receptor.2007
- Author(s)
  Uemura K., Kuzuya, A., Aoyagi, N., Ando, K., Shimozono, Y., Ninomiya, H, Shimohama, S., Kinoshita, A.
- Journal Title
  
  Neuroscience 145
- Data Source
  KAKENHI-PROJECT-18059019
[Journal Article] Amyloid beta inhibits ectodomain shedding of N-cadherin via down-regulation of cell-surface NMDA receptor2007
- Author(s)
  Uemura, K., Kuzuya, A., Aoyagi, N., Ando, K., Shimozono, Y., Ninomiya, H., Shimohama, S., Kinoshita, A
- Journal Title
  
  Neuroscience 145
  
  Pages: 5-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] GSK3beta activity modifies the localization and function of presenilin1.2007
- Author(s)
  Uemura K., Kuzuya A., Shimozono Y., Aoyagi N., Ando K., Shimohama S., & Kinoshita A.
- Journal Title
  
  Journal of Biological Chemistry 282
  
  Pages: 15823-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18059019
[Journal Article] Amyloid beta inhibits ectodomain shedding of N-cadherin via down-regulation of cell-surface NMDA receptor.2007
- Author(s)
  Uemura K., Kuzuya, A., Aoyagi, N., Ando, K., Shimozono, Y., Ninomiya, H., Shimohama, S., Kinoshita, A.
- Journal Title
  
  Neuroscience 145
- Data Source
  KAKENHI-PROJECT-18023021
[Journal Article] Amyloid beta inhibits ectodomain shedding of N-cadherinvia down-regulation of cell-surface NMDA receptor.2007
- Author(s)
  Uemura, K., Kuzuya, A., Aoyagi, N., Ando, K., Shimozono, Y., Ninomiya, H., Shimohama, S., & Kinoshita, A.
- Journal Title
  
  Neuroscience 145
  
  Pages: 510-510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18059019
[Journal Article] Activity-dependent regulation of beta-catenin via epsilon-cleavage of N-cadherin.2006
- Author(s)
  Uemura K, Kihara T, Kuzuya A, Okawa K, Nishimoto T, Bito H, Ninomiya H, Sugimoto H, *Kinoshita A, Shimohama S.
- Journal Title
  
  Biochem Biophys Res Commun. 345
  
  Pages: 951-958
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] Modulation of beta-catenin nuclear signaling via epsilon-cleavage of N-cadherin.2006
- Author(s)
  Uemura, K., Kihara T., Kuzuya, A., Okawa, K., Bito H, Ninomiya H, Sugimoto H, Kinoshita, A*, Shimohama S.* (*shared last author)
- Journal Title
  
  Biochem Biophys Res Commun 345
  
  Pages: 951-958
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] Modulation of beta-catenin nuclear signaling via epsilon-cleavage of N-cadherin.2006
- Author(s)
  Uemura, K., Kihara T., Kuzuya, A., Okawa, K., Bito H, Ninomiya H, Sugimoto H, Kinoshita, A*, Shimohama S.* (*shared last author)
- Journal Title
  
  Biochem Biophys Res Commun 345
  
  Pages: 951-958
- Data Source
  KAKENHI-PROJECT-18059019
[Journal Article] Characterization of N-cadherin cleavage by ADAM10 and Presenilin 1.2006
- Author(s)
  Uemura, K., Kihara T, Kuzuya, A., Okawa, K., Sugimoto H, Kinoshita, A*, Shimohama S.*(*shared last author)
- Journal Title
  
  Neuroscience Letters 402
  
  Pages: 278-283
- Data Source
  KAKENHI-PROJECT-18023021
[Journal Article] Characterization of N-cadherin cleavage by ADAM10 and Presenilin 1.2006
- Author(s)
  Uemura, K., Kihara T, Kuzuya, A., Okawa, K., Sugimoto H, Kinoshita, A*, Shimohama S.* (*shared last author)
- Journal Title
  
  Neuroscience Letters 402
  
  Pages: 278-283
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] Activity-dependent regulation of beta-catenin via epsilon-cleavage of N-cadherin.2006
- Author(s)
  Uemura K, Kihara T, Kuzuya A, Okawa K, Nishimoto T, Bito H, Ninomiya H, Sugimoto H, Kinoshita A, Shimohama S.
- Journal Title
  
  Biochem Biophys Res Commun. 345(3)
  
  Pages: 951-958
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590824
[Journal Article] Characterization of N-cadherin cleavage by ADAM10 and Presenilin 1.2006
- Author(s)
  Uemura, K., Kihara T, Kuzuya, A., Okawa, K., Sugimoto H, Kinoshita, A*, Shimohama S.* (*shared last author)
- Journal Title
  
  Neuroscience Letters 402
  
  Pages: 278-283
- Data Source
  KAKENHI-PROJECT-18059019
[Journal Article] The regulatory mechanism of synaptic protein translation By PS1/gamma-secretase2006
- Author(s)
  Ayae, Kinoshita, Kengo, Uemura, Koichi, Ando
- Journal Title
  
  Seikagaku 78
  
  Pages: 965-972
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] Modulation of beta-catenin nuclear signaling via epsilon-cleavage of N-cadherin.2006
- Author(s)
  Uemura, K., Kihara T., Kuzuya, A., Okawa, K., Bito H, Ninomiya H, Sugimoto H, Kinoshita, A*, Shimohama S.* (*shared last author)
- Journal Title
  
  Biochem Biophys Res Commun 345
  
  Pages: 951-958
- Data Source
  KAKENHI-PROJECT-18023021
[Journal Article] Activity-dependent regulation of beta-catenin via epsilon-cleavage of N-cadherin2006
- Author(s)
  Uemura, K., Kihara, T., Kuzuya, A., Okawa, K., Nishimoto, T., Bito, H., Ninomiya, H., Sugimoto, H., Kinoshita, A., Shimohama, S
- Journal Title
  
  Biochem Biophys Res Commun 345
  
  Pages: 951-958
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] Characterization of sequential N-cadherin cleavage by ADAM10 and PS1.2006
- Author(s)
  Uemura K, Kihara T, Kuzuya A, Okawa K, Nishimoto T, Ninomiya H, Sugimoto H, Kinoshita A, Shimohama S.
- Journal Title
  
  Neurosci Lett. 402(3)
  
  Pages: 278-283
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590824
[Journal Article] プレセニリン・γセクレターゼによるシナプスタンパク質転写制御機構2006
- Author(s)
  木下彩栄、植村健吾、安藤功一
- Journal Title
  
  生化学 78
  
  Pages: 965-972
- NAID
  10018335119
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] Characterization of sequential N-cadherin cleavage by ADAMIO. and PS12006
- Author(s)
  Uemura, K., Kihara, T., Kuzuya, A., Okawa, K., Nishimoto, T., Bito, H., Ninomiya, H., Sugimoto, H., Kinoshita, A., Shimohama, S
- Journal Title
  
  Neurosci Lett 402
  
  Pages: 278-283
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] Characterization of sequential N-cadherin cleavage by ADAM10 and PSl.2006
- Author(s)
  Uemura K, Kihara T, Kuzuya A, Okawa K, Nishimoto T, Ninomiya H, Sugimoto H, *Kinoshita A, Shimohama S.
- Journal Title
  
  Neurosci Lett. 402
  
  Pages: 278-283
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500263
[Journal Article] Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa.2005
- Author(s)
  Ihara M, Kinoshita A, Yamada S, Tanaka H, Tanigaki A, Kitano A, Goto M, Okubo K, Nishiyama H, Ogawa O, Takahashi C, Itohara S, Nishimune Y, Noda M, Kinoshita M.
- Journal Title
  
  Dev Cell. 8(3)
  
  Pages: 343-352
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590824
[Journal Article] The low density lipoprotein receptor-related protein (LRP) is a novel beta-seoretase (BACE1) substrate.2005
- Author(s)
  von Arnim CA, Kinoshita A, Peltan ID, Tangredi MM, Herl L, Lee BM, Spoelgen R, Hshieh TT, Ranganathan S, Battey FD, Liu CX, Bacskai BJ, Sever S, Irizarry MC, Strickland DK, Hyman BT.
- Journal Title
  
  J Biol Chem. 280(18)
  
  Pages: 17777-17785
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590824
[Journal Article] The LDL-receptor related protein (LRP) is a novel beta -secretase (BACE 1) substrate2005
- Author(s)
  Von Arnim C, Kinoshita A et al.
- Journal Title
  
  Journal of Biological Chemistry (印刷中)
- Data Source
  KAKENHI-PROJECT-16015265
[Journal Article] Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa2005
- Author(s)
  Ihara M, Kinoshita A et al.
- Journal Title
  
  Developmental cell 8
  
  Pages: 343-352
- Data Source
  KAKENHI-PROJECT-16015265
[Journal Article] Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa2005
- Author(s)
  Ihara M, Kinoshita A et al.
- Journal Title
  
  Developmental Cell 8
  
  Pages: 343-352
- Data Source
  KAKENHI-PROJECT-16590824
[Journal Article] The LDL-receptor related protein (LRP) is a novel beta -secretase (BACE 1) substrate2005
- Author(s)
  Von Arnim C, Kinoshita A et al.
- Journal Title
  
  Journal of Biological Chemistry (印刷中)
- Data Source
  KAKENHI-PROJECT-16044226
[Journal Article] The LDL-receptor related protein(LRP) is a novel beta-secretase(BACE 1) substrate2005
- Author(s)
  Von Arnim C, Kinoshita A et al.
- Journal Title
  
  Journal of Biological Chemistry (印刷中)
- Data Source
  KAKENHI-PROJECT-16590824
[Journal Article] Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa2005
- Author(s)
  Ihara M, Kinoshita A et al.
- Journal Title
  
  Developmental Cell 8
  
  Pages: 343-352
- Data Source
  KAKENHI-PROJECT-16044226
[Journal Article] J Neurochemistry N-cadherin enhances APP dimerization at the extracellular domain and modulates Abeta production.
- Author(s)
  Megumi Asada-Utsugi, Kengo Uemura, Yashuha Noda, Akira Kuzuya, Masato Maesako, Koichi Ando, Masakazu Kubota, Kiwamu Watanabe, Makio Takahashi, Takeshi Kihara, Shun Shimohama, Ryosuke Takahashi, Oksana Berezovska, Ayae Kinoshita
- Journal Title
  
  J Neurochemistry(accepted)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] Insight into 'synaptopathy' in Alzheimer's disease : From lifestyle to PS1/N-cadherin interaction.
- Author(s)
  Kuzuya A, Kinoshita A, Uemura K.
- Journal Title
  
  Alzheimer's Disease Research Journal 2011 (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Journal Article] Exercise is more effective than diet control in preventing high fat diet-inducedβ-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice
- Author(s)
  Masato Maesako, Kengo Uemura, Masakazu Kubota, Akira Kuzuya, Kazuki Sasaki, Naoko Hayashida, Megumi Asada-Utsugi, Kiwamu Watanabe, Maiko Uemura, TakeshiKihara, Ryosuke Takahashi, Shun Shimohama and Ayae Kinoshita
- Journal Title
  
  The Journal of Biological Chemistry
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] Environmental enrichment ameliorated high fat diet-induced Aβdeposition and memory deficit in APP transgenic mice
- Author(s)
  Maesako M, Uemura K, Kubota M, Kuzuya A, Sasaki K, Asada M, Watanabe K, Hayashida N, Ihara M, Ito H, Kihara T, Kinoshita A.
- Journal Title
  
  Neurobiology of Aging
- NAID
  120003988394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] N-cadherin enhances APP dimerization at the extra cellular domain and modulates A beta production
- Author(s)
  Asada-Utsugi M, Uemura K, Noda Y, Kuzuya A, Maesako M, Ando K, Kubota M, Watanabe K, Takahashi M, Kihara T, Shimohama S, Takahashi R, Berezovska O, Kinoshita A.
- Journal Title
  
  J Neurochem
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659529
[Journal Article] Presenilin regulates insulin signaling via gamma-secretase independent mechanism.
- Author(s)
  Masato Maesako, Kengo Uemura, Akira Kuzuya, Megumi Asada, Kazuki Sasaki, Kiwamu Watanabe, Koichi Ando, Masakazu Kubota, Takeshi Kihara, Ayae Kinoshita
- Journal Title
  
  J Biological Chemistry (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] 関節リウマチ患者におけるサルコペニアの新規発症リスク要因：KURAMAコホート研究2021
- Author(s)
  鳥井美江　板谷崇央　谷河杏介　浦井祐希　木下彩栄　任和子　渡部龍　村田浩一　村上孝作田中真生　伊藤宣　松田秀一　森信暁雄　荒井秀典　橋本求
- Organizer
  第8回日本サルコペニア・フレイル学会
- Data Source
  KAKENHI-PROJECT-19K11165
[Presentation] 最大の内分泌器官である筋の役割2021
- Author(s)
  野田泰葉、木下彩栄
- Organizer
  日本整形外科学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K11415
[Presentation] VocabChecker: Measuring Language Abilities for Detecting Early Stage Dementia2018
- Author(s)
  Daisaku Shibata, Shoko Wakamiya, Kaoru Ito, Mai Miyabe, Ayae Kinoshita, Eiji Aramaki
- Organizer
  In Processing of IUI
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K12489
[Presentation] 日本語におけるIdea Density：認知症の早期発見を目指して2017
- Author(s)
  柴田大作，伊藤薫，若宮翔子，木下彩栄，荒牧英治
- Organizer
  第37回医療情報学連合大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K12489
[Presentation] Detecting Alzheimer’s Disease based on Word Category Frequencies2016
- Author(s)
  Daisaku Shibata, Shoko Wakamiya, Ayae Kinoshita, Eiji Aramaki
- Organizer
  Proceedings of the International Conference on Computational Linguistics (COLING) workshop on ClinicalNLP
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K12489
[Presentation] Bone Morphogenic Protein Expression in Pericytes Is a Pathological Correlate of Vascular Cognitive Impairment2014
- Author(s)
  Maiko Uemura1; Masafumi Ihara2; Kazuyuki Nagatsuka2; Ayae Kinoshita3; Ryosuke Takahashi1
- Organizer
  International Stroke Conference 2014
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PUBLICLY-24111524
[Presentation] アルツハイマー病におけるアストロサイトからのIGFBPの関与2013
- Author(s)
  渡邉究　植村健吾　浅田めぐみ　前迫真人　上田かりん　上村麻衣子　久保田正和　木原武士　秋山治彦　下濱俊　高橋良輔　木下彩榮
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PUBLICLY-24111524
[Presentation] 運動は継続しなければ高脂肪食によって引き起こされる記憶障害およびβ–アミロイドの蓄積を改善できない2013
- Author(s)
  Masato Maesako, Ayana Iwata, Masakazu Kubota, Kengo Uemura and Ayae Kinoshita
- Organizer
  第36回日本神経科学学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PUBLICLY-24111524
[Presentation] Exercise is effective in preventing high fat diet-induced β-amyloid deposition and memory deficit but continuation is necessary in amyloid precursor protein transgenic mice2013
- Author(s)
  Masato Maesako, Masakazu Kubota, Kengo Uemura and Ayae Kinoshita
- Organizer
  International Conference on Alzheimer's Disease 2013 (AAIC)
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PUBLICLY-24111524
[Presentation] アルツハイマー病の発症メカニズムに基づく新しい予防戦略2013
- Author(s)
  木下彩栄
- Organizer
  日本薬理学会シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2013-03-21
- Invited
- Data Source
  KAKENHI-PUBLICLY-24111524
[Presentation] the relationship between IGFBP released from astrocytes and Alzheimer's disease（AD）2013
- Author(s)
  渡邉究　植村健吾　浅田めぐみ　前迫真人　上田かりん　上村麻衣子　久保田正和　木原武士　秋山治彦　下濱俊　高橋良輔　木下彩榮
- Organizer
  International Conference on Alzheimer's Disease 2013 (AAIC)
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PUBLICLY-24111524
[Presentation] 認知症医療の最新の潮流2012
- Author(s)
  木下彩栄
- Organizer
  日本認知症予防学会　ランチョンセミナー
- Place of Presentation
  北九州
- Year and Date
  2012-09-09
- Invited
- Data Source
  KAKENHI-PUBLICLY-24111524
[Presentation] N-カドヘリンはAPPの細胞外ドメインダイマー化を促進し、Abeta産生を促進する2011
- Author(s)
  浅田めぐみ、植村健吾、木下彩栄他
- Organizer
  神経科学会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-23591243
[Presentation] アルツハイマー病の最前線2011
- Author(s)
  木下彩栄
- Organizer
  福知山医師会
- Place of Presentation
  福知山医師会(招待講演)
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] テレビ電話を用いた定期的な介入が糖尿病患者の血糖コントロールに与える影響2011
- Author(s)
  久保田正和、細田公則、江口恭子、古家彩名、西嶋ゆき、中尾一和、木下彩栄
- Organizer
  日本在宅医療学会学術集会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-06-29
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] テレビ電話を用いた定期的な介入が糖尿病患者の血糖コントロールに与える影響2011
- Author(s)
  久保田正和、細田公則、江口恭子、古家彩名、西嶋ゆき、中尾一和、木下彩栄
- Organizer
  日本在宅医療学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-06-29
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] ITを利用した在宅支援の取り組み2011
- Author(s)
  木下彩栄
- Organizer
  乙訓郡医師会
- Place of Presentation
  乙訓郡医師会(招待講演)
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] アルツハイマー病の最前線2011
- Author(s)
  木下彩栄
- Organizer
  福知山医師会招待講演
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] ITを利用した在宅支援のとりくみ乙訓郡2011
- Author(s)
  木下彩栄
- Organizer
  医師会招待講演
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] Effects of Presenilin 1 phosphorylation on Insulin Receptor2010
- Author(s)
  前迫真人、植村健吾、久保田正和、安藤功一、葛谷聡、山田奈央、浅田めぐみ、秋山治彦、木下彩栄
- Organizer
  神経科学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] Presenilinl, a causahve gene for Alzheimer's disease, is regulated by insulin signaling2010
- Author(s)
  Kinoshita A
- Organizer
  International Conference for Alzheimer's disease (Peking University)
- Place of Presentation
  中国北京市
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] Presenilin1, a causative gene for Alzheimer's disease, is regulated by insulin signaling2010
- Author(s)
  Kinoshita A
- Organizer
  International Conference for Alzheimer's disease(Peking University)
- Place of Presentation
  中国北京市
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] インスリンシグナルがプレセニリンの局在・機能に与える影響の解明2010
- Author(s)
  木下彩栄、前迫真人、浅田めぐみ、葛容聡、安藤功一、久保田正和、植村健吾、秋山治彦
- Organizer
  日本神経学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] ITを利用した双方向性コミュニケーションによる患者支援システム2010
- Author(s)
  古家彩名、保利美也子、久保田正和、武地一、木下彩栄
- Organizer
  日本認知症ケア学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] Effects of Presenilin 1 phosphorylation on Insulin Receptor.2010
- Author(s)
  前迫真人、植村健吾、久保田正和、安藤功一、葛谷聡、山田奈央、浅田めぐみ、秋山治彦、木下彩栄
- Organizer
  神経科学会
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] インスリンシグナルがプレセニリンの局在・機能に与える影響の解明2010
- Author(s)
  木下彩栄、前迫真人、浅田めぐみ、葛谷聡、安藤功一、久保田正和、植村健吾、秋山治彦
- Organizer
  日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] Analysis of N-cadherin interacting proteins in Alzheimer's disease.2010
- Author(s)
  Koichi A, Maesako M, Asada M, Aoyagi N, Kubota M, Kuzuya A, Uemura K, Kawamata J, Takahashi R, Kinoshita A
- Organizer
  International Conference of Alzheimer's disease.
- Place of Presentation
  米国ハワイ州
- Year and Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] Analysis of N-cadherin interacting proteins in Alzheimer's disease2010
- Author(s)
  Koichi A, Maesako M, Asada M, Aoyagi N, Kubota M, Kuzuya A, Uemura K, Kawamata J, Takahashi R, Kinoshita A
- Organizer
  International Conference of Alzheimer's disease
- Place of Presentation
  米国ハワイ州ホノルル
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] APPシスダイマー化におけるN-cadherin、ネクチン1の影響2010
- Author(s)
  浅田めぐみ、植村健吾、葛谷聡、山田奈央、前迫真人、安藤功一、渡辺究、久保田正和、Oksana Berezovska, Brad Hyman, 下浜俊、高橋良輔、木下彩栄
- Organizer
  神経科学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] Effects of Presenilin 1 phosphorylation on Insulin Receptor2010
- Author(s)
  前迫真人、植村健吾、久保田正和、安藤功一、葛谷聡、山田奈央、浅田めぐみ、秋山治彦、木下彩栄
- Organizer
  神経科学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] Analysis of N-cadherin interacting proteins in Alzheimer's disease2010
- Author(s)
  Koichi A, Maesako M, Asada M, Aoyagi N, Kubota M, Kuzuya A, Uemura K, Kawamata J, Takahashi R, Kinoshita A
- Organizer
  International Conference of Alzheimer's disease
- Place of Presentation
  米国ハワイ州ホノルル
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] APPシスダイマー化におけるN-cadherin、ネクチン1の影響2010
- Author(s)
  浅田めぐみ、植村健吾、葛谷聡、山田奈央、前迫真人、安藤功一、渡辺究、久保田正和、Oksana Berezovska, Brad Hyman, 下浜俊、高橋良輔、木下彩栄
- Organizer
  神経科学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] Presenilin 1, a causative gene for Alzheimer's disease, is regulated by insulin.2010
- Author(s)
  木下彩栄
- Organizer
  International Conference for Alzheimer's disease (Peking University).
- Place of Presentation
  中国北京
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] インスリンシグナルがPS1に与える影響の解明2010
- Author(s)
  前迫真人、植村健吾、佐々木和樹、安藤功一、葛谷聡、浅田めぐみ、久保田正和、秋山治彦、木下彩栄
- Organizer
  日本認知症学会
- Place of Presentation
  名古屋
- Year and Date
  2010-11-06
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] インスリンシグナルがPS1に与える影響の解明2010
- Author(s)
  前迫真人、植村健吾、佐々木和樹、安藤功一、葛谷聡、浅田めぐみ、久保田正和、秋山治彦、木下彩栄
- Organizer
  日本認知症学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] APPシスダイマー化におけるN-cadherin2010
- Author(s)
  浅田めぐみ、植村健吾、葛谷聡、山田奈央、前迫真人、安藤功一、渡辺究、久保田正和、Oksana Berezovska, Brad Hyman, 下浜俊、高橋良輔、木下彩栄
- Organizer
  ネクチン1の影響神経科学会
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] インスリンシグナルを介したプレセニリン1の機能制御2009
- Author(s)
  前迫真人, 植村健吾, 久保田正和, 青柳信寿, 葛谷聡, 安藤功一, 池内健, 浅田めぐみ, 木下彩栄
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] 在宅要介護高齢者を介護する家族主介護者の結婚満足度と介護要因の検討2009
- Author(s)
  日吉和子、カール・ベッカー、木下彩栄
- Organizer
  日本在宅医療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] 在宅要介護高齢者を介護する家族主介護者の結婚満足度と介護要因の検討2009
- Author(s)
  日吉和子, カール・ベッカー, 木下彩栄
- Organizer
  日本在宅医療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] アルツハイマー病におけるN-カドヘリン関連たんぱく質の解析2009
- Author(s)
  安藤功一, 前迫真人, 浅田めぐみ, 久保田正和, 青柳信寿, 植村健吾, 葛谷聡, 川又純, 高橋良輔, 木下彩栄
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] APPダイマー化におけるN-カドヘリンの影響2009
- Author(s)
  浅田めぐみ, 植村健吾, 葛谷聡, 渡辺拡人, 久保田正和, 下濱俊, 高橋良輔, 木下彩栄
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] 認知症患者の尊厳死に対する意識調査2009
- Author(s)
  古家彩名, 久保田正和, 木下彩栄
- Organizer
  認知症ケア学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] 認知症の病態とケア2009
- Author(s)
  木下彩栄
- Organizer
  聖母女学院短期大学特別講演
- Place of Presentation
  聖母女学院短期大学
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] インスリンシグナルを介したプレセニリン1の機能制御2009
- Author(s)
  前迫真人, 植村健吾, 久保田正和, 青柳信寿, 葛谷聡, 安藤功一, 池内健, 浅田めぐみ, 木下彩栄
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] 認知症の病態と治療の現状2009
- Author(s)
  木下彩栄
- Organizer
  日本作業療法士協会専門作業療法士取得研修
- Place of Presentation
  京都大学
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] 細胞内たんぱく質分解系がPS1によるAPPの切断に及ぼす影響の検討2009
- Author(s)
  渡辺拡人, 葛谷聡, 浅田めぐみ, 植村健吾, 渡辺拡人, 前迫真人, 久保田正和, 高橋良輔, 木下彩栄
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] 認知症高齢者の身体合併症に対する一般病院の対応2009
- Author(s)
  江口恭子、木下彩栄
- Organizer
  認知症ケア学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] IT利用が在宅介護者の介護ストレスに与える影響2009
- Author(s)
  久保田正和、保利美也子、宋慶華、日吉和子、木下彩栄
- Organizer
  日本老年看護学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] APPダイマー化に対するN-カドヘリンの影響2009
- Author(s)
  浅田めぐみ, 植村健吾, 葛谷聡, 久保田正和, 下浜俊, 高橋良輔, 木下彩栄
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] プレセニリンのリン酸化がインスリン受容体の切断に与える影響2009
- Author(s)
  前迫真人, 植村健吾, 久保田正和, 安藤功一, 葛谷聡, 浅田めぐみ, 渡辺拡人, 山田奈央, 秋山治彦, 木下彩栄
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] 在宅認知症高齢者とその家族介護者に対するテレビ電話システムを用いたコミュニケーションの有効性2009
- Author(s)
  保利美也子, 久保田正和, 安藤功一, 木原武士, 高橋良輔, 木下彩栄
- Organizer
  日本在宅医療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] 在宅認知症高齢者とその家族介護者に対するテレビ電話を用いたコミュニケーションの有効性2009
- Author(s)
  保利美也子、久保田正和、安藤功一、木原武士、高橋良輔、木下彩栄
- Organizer
  日本在宅医療学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-21890105
[Presentation] 認知症の病態と治療の現状2009
- Author(s)
  木下彩栄
- Organizer
  日本作業療法士協会専門作業療法士取得研修
- Place of Presentation
  京都大学
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] 認知症の病態とケア2009
- Author(s)
  木下彩栄
- Organizer
  聖母女学院短期大学特別講演
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] プレセニリンのリン酸化がインスリン受容体の切断に与える影響2009
- Author(s)
  前迫真人, 植村健吾, 久保田正和, 安藤功一, 葛谷聡, 浅田めぐみ, 渡辺拡人, 山田奈央, 秋山治彦, 木下彩栄
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] アルツハイマー病におけるN-カドヘリン関連たんぱく質の解析2009
- Author(s)
  安藤功一, 前迫真人, 浅田めぐみ, 久保田正和, 青柳信寿, 植村健吾, 葛谷聡, 川又純, 高橋良輔, 木下彩栄
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] APPダイマー化におけるN-カドヘリンの影響2009
- Author(s)
  浅田めぐみ, 植村健吾, 葛谷聡, 渡辺拡人, 久保田正和, 下濱俊, 高橋良輔, 木下彩栄
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] 細胞内たんぱく質分解系がPS1によるAPPの切断に及ぼす影響の検討2009
- Author(s)
  渡辺拡人, 葛谷聡, 浅田めぐみ, 植村健吾, 渡辺拡人, 前迫真人, 久保田正和, 高橋良輔, 木下彩栄
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] 認知症患者の尊厳死に対する意識調査2009
- Author(s)
  古家彩名、久保田正和、木下彩栄
- Organizer
  認知症ケア学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] APPダイマー化に対するN-カドヘリンの影響2009
- Author(s)
  浅田めぐみ, 植村健吾, 葛谷聡, 久保田正和, 下浜俊, 高橋良輔, 木下彩栄
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] 認知症高齢者の身体合併症に対する一般病院の対応2009
- Author(s)
  江口恭子, 木下彩栄
- Organizer
  認知症ケア学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] IT利用が在宅介護者の介護ストレスに与える影響2009
- Author(s)
  久保田正和, 保利美也子, 宋慶華, 日吉和子, 木下彩栄
- Organizer
  日本老年看護学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] 在宅認知症高齢者とその家族介護者に対するテレビ電話システムを用いたコミュニケーションの有効性2009
- Author(s)
  保利美也子、久保田正和、安藤功一、木原武士、高橋良輔、木下彩栄
- Organizer
  日本在宅医療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] 認知症の病態とケア2009
- Author(s)
  木下彩栄
- Organizer
  聖母女学院短期大学特別講演
- Place of Presentation
  聖母女学院短期大学
- Data Source
  KAKENHI-PROJECT-21659529
[Presentation] N-カドヘリンのプレセニリン・γセクレターセクレターゼ機能に与える影響2008
- Author(s)
  植村健吾, 青柳信寿, 安藤功一, 浅田めぐみ, 下浜俊, 高橋良輔, 木下
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-20300124
[Presentation] スカイプとWebカメラを使用した在宅認知症患者とその介護者への支援2008
- Author(s)
  保利美也子, 久保田正和, 木下彩栄
- Organizer
  第19回日本在宅医療学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2008-07-27
- Data Source
  KAKENHI-PROJECT-19890116
[Presentation] 高齢者介護における精神的問題2008
- Author(s)
  日吉和子、カール・ベッカー、木下彩栄
- Organizer
  第78回日本衛生学会
- Place of Presentation
  熊本
- Year and Date
  2008-03-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Presentation] スカイプを用いた在宅認知症患者とその家族への支援システムの有効性2008
- Author(s)
  保利美也子、久保田正和、木原武士、高橋良輔、木下彩栄
- Organizer
  第19回日本老年医学会近畿地方会
- Place of Presentation
  京都
- Year and Date
  2008-11-15
- Data Source
  KAKENHI-PROJECT-19890116
[Presentation] スカイプとウェブカメラを使用した在宅認知症患者とその介護者への支援2008
- Author(s)
  保利美也子、久保田正和、木下彩栄
- Organizer
  第19回日本在宅医療学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2008-07-28
- Data Source
  KAKENHI-PROJECT-19890116
[Presentation] カドヘリン切断に対するアミロイドβ蛋白の影響2007
- Author(s)
  植村健吾、葛谷聡、青柳信寿、安藤功一、下濱俊、木下彩栄
- Organizer
  第48回日本神経学会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-16
- Data Source
  KAKENHI-PROJECT-18023021
[Presentation] Tne N-cadherin enhances extracelluar secretion of Abeta and modulates Ab40/42 ratio2007
- Author(s)
  Uemura, K., Aoyagi, N., Ando, K., Takahashi, R., Shimohama, S., Kinoshita, A
- Organizer
  26th Japan Society for Dementia
- Place of Presentation
  Osaka
- Year and Date
  2007-10-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Presentation] N-cadherin enhances extracellular secretion of Abeta and modulates Abeta42/40 ratio.2007
- Author(s)
  植村健吾、青柳信寿、安藤功一、高橋良輔、下濱俊、木下彩栄
- Organizer
  第26回日本認知症学会
- Place of Presentation
  大阪
- Year and Date
  2007-10-07
- Data Source
  KAKENHI-PROJECT-18023021
[Presentation] 介護における殺人の傾向2007
- Author(s)
  日吉和子、カール・ベッカー、木下彩栄
- Organizer
  第11回日本健康福祉政策学会
- Place of Presentation
  岡山
- Year and Date
  2007-12-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Presentation] 細胞の接着状態によるgammaセクレターゼの構造と切断機能の調節2007
- Author(s)
  木下彩栄
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  東京
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Presentation] カドヘリン切断に対するアミロイドβ蛋白の影響2007
- Author(s)
  植村健吾、葛谷聡、青柳信寿、安藤功一、下濱俊、木下彩栄
- Organizer
  第48回日本神経学会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-16
- Data Source
  KAKENHI-PROJECT-18059019
[Presentation] カドヘリン切断に対するアミロイドβ蛋白の影響2007
- Author(s)
  植村健吾、青柳信寿、安藤功一、高橋良輔、下濱俊、木下彩栄
- Organizer
  第48回日本神経学会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Presentation] N-cadherin enhances extracellular secretion of Abeta and modulates Abeta42/40 ratio.2007
- Author(s)
  植村健吾、青柳信寿、安藤功一、高橋良輔、下濱俊、木下彩栄
- Organizer
  第26回日本認知症学会
- Place of Presentation
  大阪
- Year and Date
  2007-10-07
- Data Source
  KAKENHI-PROJECT-18059019
[Presentation] Presenilin-mediated substrate cleavage2007
- Author(s)
  Ayae, Kinoshita
- Organizer
  127th Japan Pharmaceutical Society
- Place of Presentation
  Toyama
- Year and Date
  2007-03-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Presentation] 細胞の接着状態によるgammaセクレターゼの構造と切断機能の調節2007
- Author(s)
  木下彩栄
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  東京
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18023021
[Presentation] The effect of amyloid beta protein on cadherin cleavage2007
- Author(s)
  Uemura, K., Aoyagi, N., Ando, K., Takahashi, R., Shimohama, S., Kinoshita, A
- Organizer
  48th Japan Society of Neurologica
- Place of Presentation
  Nagoya
- Year and Date
  2007-05-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Presentation] N-cadherin enhances extracellular secretion of Abeta and modulates Abeta42/40 ratio.2007
- Author(s)
  植村健吾、青柳信寿、安藤功一、高橋良輔、下濱俊、木下彩栄
- Organizer
  第26回日本認知症学会
- Place of Presentation
  大阪
- Year and Date
  2007-10-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500263
[Presentation] 細胞の接着状態によるgammaセクレターゼの構造と切断機能の調節2007
- Author(s)
  木下彩栄
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  東京
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18059019
[Presentation] プレセニリンの基質切断機構2007
- Author(s)
  木下彩栄
- Organizer
  第127年会日本薬学会シンポジウム
- Place of Presentation
  富山
- Year and Date
  2007-03-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500263

1. UEMURA Kengo (00378663)

# of Collaborated Projects: 6 results

# of Collaborated Products: 78 results
2. KUBOTA Masakazu (80452267)

# of Collaborated Projects: 4 results

# of Collaborated Products: 39 results
3. SIGEMOTO Ryuichi (20221294)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HORI Miyako (70547562)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. Mie Torii (60615285)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. 荒井秀典 (60232021)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 任和子 (40243084)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. KOIKE Teruhiko (90262906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ISA Tadashi (20212805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ARAMAKI Eiji (70401073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 橋本求 (60512845)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. 日吉和子 (80760248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 大石直也 (40526878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 森信暁雄 (10294216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 大西輝 (60634269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 板谷崇央 (70963536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. FURUYA Ayana

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 下濱俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 伊東秀文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 高橋良輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kinoshita Ayae 木下 彩栄

KINOSHITA Ayae 木下 彩栄

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認知症患者における認知機能と運動機能・運動関連マイオカインとの関連の解析Principal Investigator

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Preventitive Effect of amyloid beta production in Alzheimer's disease by myokines after exercisePrincipal Investigator

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グリア細胞内のカルシウム調節破綻を介した神経変性過程の解明Principal Investigator

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The development of the bi-directional support system for the homecare patients by using SkypePrincipal Investigator

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Analysis of the mechanism of pathological synaptic alterations in Alzheimer's diseasePrincipal Investigator

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プレセニリン機能障害によるシナプス制御機構の破綻Principal Investigator

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Kinoshita Ayae 木下彩栄

KINOSHITA Ayae 木下彩栄