INOUE Akihiro 井上明宏

… Alternative Names

INOUE AKIHIRO 井上明宏

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Researcher Number	80322080
Affiliation (Current)	2025: 日本赤十字看護大学, 看護学部, 教授
Affiliation (based on the past Project Information) *help	2015: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授 2013 – 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 准教授 2010 – 2011: 東京医科歯科大学, 大学院・医歯学総合研究科, 准教授 2009: Tokyo Medical and Dental University, 医歯学総合研究科, 准教授 2007: 東京医科歯科大学, 大学院・医歯学総合研究科, 准教授 … More 2006: Tokyo Medical and Dental University, Graduate School, Associate Professor, 大学院医歯学総合研究科, 助教授 2000 – 2005: 東京医科歯科大学, 大学院・医歯学総合研究科, 助教授 2003: Tokyo Medical and Dental University, Graduate School, Associate Professor, 大学院・歯学総合研究科, 助教授 Less
Review Section/Research Field	Principal Investigator Nerve anatomy/Neuropathology / General anatomy (including Histology/Embryology) Except Principal Investigator Biological Sciences / Nerve anatomy/Neuropathology / General anatomy (including Histology/Embryology) / General anatomy (including histology/embryology)
Keywords	Principal Investigator GFP / シナプス形成 / シナプス後肥厚部 / Adenovirus vector / Synapse formation / アデノウイルスベクター / カドヘリン / 組織培養系 / fluorescent recovery after photobleaching / hippocampal culture … More / actin / post synaptic density / green fluorescent protein / RNA interference / virus vector / synapse scaffolding protein / 二光子レーザー顕微鏡 / 脳組織器官培養標本 / トランスジェニックマウス / FRAP / 海馬培養神経細胞 / アクチン / 緑色蛍光タンパク質 / RNA干渉 / ウィルスベクター / シナプス足場タンパク質 / Cre-loxP system / Two-photon laser microscopy / Sindbis virus vector / Tissue culture / Postsynaptic density / Cre-loxP / 二光子励起レーザー走査顕微鏡 / シンドビスウィルスベクター / Laminar specificity / Cadherin / Cell adhesion molecule / Organotypic culture / Retino-tectal projection / アデノウィルスベクター / 網膜-視蓋投射 / 層特異性 / 細胞接着分子 / 網膜一視蓋投射 / PAC / アデニル酸シクラーゼ / 神経突起伸展 / メラノサイト / エレクトロポレーション / 光活性化アデニル酸シクラーゼ / 光活性化 / 細胞内シグナル伝達 / cAMP / 神経突起形成 … More Except Principal Investigator 神経培養 / 蛍光顕微鏡法 / シナプス / 樹状突起 / 海馬 / fluorescence microscopy / synapse / シグナル伝達 / cultured neurons / plasticity / glutamate receptors / シナプス可塑性 / シナプス後肥厚部 / グルタミン酸受容体 / intracellular calcium / green fluorescent protein(GFP) / dendritic spine / postsynaptic density / hippocampus / 神経科学 / 細胞組織 / 解剖学 / 光スイッチ / 細胞運動 / 細胞骨格 / G蛋白 / 軸索 / 軸素 / グリア細胞 / バイオイメージング / 細胞・組織 / 脳・神経 Less

Optogenetic study of multi functional signaling molecules such as RAC1 CDC42 and PI3K
- Principal Investigator
  
  NAKATA TAKAO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Tokyo Medical and Dental University
Application of photoactivated adenylyl cyclase to study the mechanisims of neurite formation by controlling temporal and spacial intracellular cAMP level in vitroPrincipal Investigator
- Principal Investigator
  
  INOUE Akihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tokyo Medical and Dental University
Live-cell imaging studies of central nervous system synapse formation and alteration.Principal Investigator
- Principal Investigator
  
  INOUE Akihiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tokyo Medical and Dental University
機能分子イメージングを用いたグリア・ニューロン相互作用の解析
- Principal Investigator
  
  岡部繁男
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  Tokyo Medical and Dental University
Dynamics of postsynaptic density proteins and its relation to synapse functions
- Principal Investigator
  
  OKABE Shigeo
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Tokyo Medical and Dental University
海馬神経細胞でのシナプス機能分子と細胞骨格の相互作用
- Principal Investigator
  
  岡部繁男
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Live tissue imaging of functions and dynamics of membrane associated proteins during development of neuronal network formationPrincipal Investigator
- Principal Investigator
  
  INOUE Akihiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Tokyo Medical and Dental University, Graduate School
海馬神経細胞でのNMDA受容体分子の動態解析
- Principal Investigator
  
  岡部繁男
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
海馬神経細胞でのNMDA受容体分子の動態解析
- Principal Investigator
  
  OKABE Shigeo
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Analysis of Molecular Assembly of Synaptic Molecules during Development
- Principal Investigator
  
  OKABE Shigeo
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tokyo Medical and Dental University
Functions of neuronal membrane-associated proteins for neuronal connection and synapase formation.Principal Investigator
- Principal Investigator
  
  INOUE Akihiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Tokyo Medical & Dental University

All 2009 2006 2005 2003 Other

All Journal Article Presentation

[Journal Article] Critical involvement of Rho GTPase activity in the efficient transplantation of neural stem cells into the injured spinal cord2009
- Author(s)
  Numano F, Inoue A, Enomoto M, Shinomiya K, Okawa A and Okabe S
- Journal Title
  
  Mol Brain
  
  Volume: Vol.2 Pages: 37-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590211
[Journal Article] Kinase-dead knock-in mouse reveals an essential role of kinase activity of Ca2+/calmodulin-dependent protein kinase IIalpha in dendritic spine enlargement, long-term potentiation, and learning2009
- Author(s)
  Yamagata Y, Kobayashi S, Umeda T, Inoue A, Sakagami H, Fukaya M, Watanabe M, Hatanaka N, Totsuka M, Yagi T, Obata K, Imoto K, Yanagawa Y, Manabe T, Okabe S
- Journal Title
  
  Journal of Neuroscience
  
  Volume: Vol.29 Pages: 7607-7618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590211
[Journal Article] Differential control of postsynaptic density scaffolds via actin-dependent and independent mechanisms.2006
- Author(s)
  Kuriu, T., Inoue, A., Bito, H., Sobue, K., S.Okabe
- Journal Title
  
  Journal of Neuroscience 26
  
  Pages: 7693-7706
- Data Source
  KAKENHI-PROJECT-15082203
[Journal Article] Differential control of postsynaptic density scaffolds via actin-dependent and independent mechanisms.2006
- Author(s)
  Kuriu, T., Inoue, A., Bito, H., Sobue, K., Okabe, S.
- Journal Title
  
  Journal of Neuroscience 26
  
  Pages: 7693-7706
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590152
[Journal Article] The RNA-binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology.2005
- Author(s)
  Fujii, R.*, Okabe, S.*, Urushido, T., Inoue, K., Tachibana, T., Nishikawa, T., Hick, G.G., T.Takumi.(* equal contribution.)
- Journal Title
  
  Current Biology 15
  
  Pages: 587-593
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590152
[Journal Article] Bi-directional regulation of postsynaptic cortactin distribution by BDNF and NMDA receptor activity2005
- Author(s)
  Iki, J., Inoue, A., Bito, H., S.Okabe
- Journal Title
  
  European Journal of Neuroscience 22
  
  Pages: 2985-2994
- Data Source
  KAKENHI-PROJECT-15082203
[Journal Article] Bi-directional regulation of postsynaptic cortactin distribution by BDNF and NMDA receptor activity.2005
- Author(s)
  Iki, J., Inoue, A., Bito, H., Okabe, S.
- Journal Title
  
  European Journal of Neuroscience 22
  
  Pages: 2985-2994
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590152
[Journal Article] The RNA-binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology.2005
- Author(s)
  Fujii, R.^*, Okabe, S.^*, Urushido, T., Inoue, K., Yoshimura, A., Tachibana, T., Nishikawa, T., Hick, G.G., T.Takumi ^* equal contribution
- Journal Title
  
  Current Biology 15
  
  Pages: 587-593
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15200027
[Journal Article] The RNA-binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology.2005
- Author(s)
  Fujii, R.^*, Okabe, S.^*, Urushido, T., Inoue, K., Yoshimura, A., Tachibana, T., Nishikawa, T., Hick, G.G., T.Takumi ^* equal contribution
- Journal Title
  
  Current Biology 15
  
  Pages: 587-593
- Data Source
  KAKENHI-PROJECT-15082203
[Journal Article] The RNA-binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology.2005
- Author(s)
  Fujii, R., Okabe, S., Urushido, T., Inoue, K., Yoshimura, A., Tachibana, T., Nishikawa, T., Hick, G.G., T.Takumi, equal contribution
- Journal Title
  
  Current Biology 15
  
  Pages: 587-593
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15200027
[Journal Article] Bi-directional regulation of postsynaptic cortactin distribution by BDNF and NMDA receptor activity2005
- Author(s)
  Iki, J., Inoue, A., Bito, H., S.Okabe
- Journal Title
  
  European Journal of Neuroscience 22
  
  Pages: 2985-2994
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15200027
[Journal Article] p250GAP, a novel brain-enriched GTPase-activating protein for Rho family GTPase, is involved in the NMDA receptor signaling.2003
- Author(s)
  Nakazawa T, Watabe A M, Tezuka T, Yoshida Y, Yokoyama K, Umemori H, Inoue A, Okabe S, Manabe T, Yamamoto T
- Journal Title
  
  Molecular Biology of the Cell 14
  
  Pages: 2921-2934
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580723
[Journal Article] The dynamic organization fo postsynaptic proteins : translocating molecules regulate synaptic function.2003
- Author(s)
  Inoue A, Okabe S
- Journal Title
  
  Current Opinion in Neurobiology 13
  
  Pages: 332-340
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580723
[Journal Article] p250GAP, a novel brain-enriched GTPase-activating protein for Rho family GTPase, is involved in the NMDA receptor signaling.2003
- Author(s)
  Nakazawa, T., Watabe, A.M., Tezuka, T., Yoshida, Y., Yokoyama, K., Umemori, H., Inoue, A., Okabe, S., Manabe, T., T.Yamamoto.
- Journal Title
  
  Molecular Biology of the Cell 13
  
  Pages: 2921-2934
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15200027
[Journal Article] The dynamic organization of postsynaptic proteins : translocating molecules regulate synaptic function.2003
- Author(s)
  Inoue A.
- Journal Title
  
  Current Opinion in Neurobiology 13
  
  Pages: 332-340
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580723
[Journal Article] The dynamic organization of postsynaptic proteins : translocating molecules regulate synaptic function.2003
- Author(s)
  Inoue A., S.Okabe
- Journal Title
  
  Current Opinion in Neurobiology 13
  
  Pages: 332-340
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15200027
[Journal Article] The RNA-binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology.
- Author(s)
  Fujii, R.^*, Okabe, S.^*, Urushido, T., Inoue, K., Tachibana, T., Nishikawa, T., Hick, G.G., T.Takumi
- Journal Title
  
  Current Biology in press
- Data Source
  KAKENHI-PROJECT-15200027
[Journal Article] The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology.
- Author(s)
  Fujii, R.^*, Okabe, S.^*, Urushido, T., Inoue, K., Tachibana T., Nishikawa, T., Hick, G.G., T.Takumi
- Journal Title
  
  Current Biology (in press)
- Data Source
  KAKENHI-PROJECT-15082203
[Presentation] THE ROLE OF KINASE ACTIVITY OF Ca2+/CALMODULIN-DEPENDENT PROTEIN KINASE II IN HIPPOCAMPAL SYNAPTIC PLASTICITY AND LEARNING2009
- Author(s)
  Yoko Yamagata, Shizuka Kobayashi, Tatsuya Umeda, Akihiro Inoue, Hiroyuki Sakagami, Masahiro Fukaya, Masahiko Watanabe, Nobuhiko Hatanaka, Masako Totsuka, Takeshi Yagi, Kunihiko Oabata, Keiji Imoto, Yuchio Yanagawa, Toshiya Manabe, Shigeo Okabe
- Organizer
  The 36th International Congress of Physiological Sciences
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21590211
[Presentation] カルモジュリン依存性プロテインキナーゼII & alpha ;活性は海馬シナプス可塑性の構造学的・機能学的・行動学的発現に不可欠2009
- Author(s)
  山肩葉子、小林静香、梅田達也、井上明宏、阪上洋行、深谷昌弘、渡邉雅彦、畑中伸彦、戸塚昌子、八木健、小幡邦彦、井本敬二、柳川右千夫、真鍋俊也、岡部繁男
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21590211

1. OKABE Shigeo (60204012)

# of Collaborated Projects: 9 results

# of Collaborated Products: 15 results
2. NAKATA Takao (50218004)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. ISHII TOMOHORO (60549947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

INOUE Akihiro 井上 明宏

INOUE AKIHIRO 井上 明宏

Research Projects

Research Products

Co-Researchers

Optogenetic study of multi functional signaling molecules such as RAC1 CDC42 and PI3K

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of photoactivated adenylyl cyclase to study the mechanisims of neurite formation by controlling temporal and spacial intracellular cAMP level in vitroPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Live-cell imaging studies of central nervous system synapse formation and alteration.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

機能分子イメージングを用いたグリア・ニューロン相互作用の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Dynamics of postsynaptic density proteins and its relation to synapse functions

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

海馬神経細胞でのシナプス機能分子と細胞骨格の相互作用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Live tissue imaging of functions and dynamics of membrane associated proteins during development of neuronal network formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

海馬神経細胞でのNMDA受容体分子の動態解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

海馬神経細胞でのNMDA受容体分子の動態解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of Molecular Assembly of Synaptic Molecules during Development

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functions of neuronal membrane-associated proteins for neuronal connection and synapase formation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Critical involvement of Rho GTPase activity in the efficient transplantation of neural stem cells into the injured spinal cord2009

Author(s)

Journal Title

Data Source

[Journal Article] Kinase-dead knock-in mouse reveals an essential role of kinase activity of Ca2+/calmodulin-dependent protein kinase IIalpha in dendritic spine enlargement, long-term potentiation, and learning2009

Author(s)

Journal Title

Data Source

[Journal Article] Differential control of postsynaptic density scaffolds via actin-dependent and independent mechanisms.2006

INOUE Akihiro 井上明宏

INOUE AKIHIRO 井上明宏