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Tamura Yasuaki  田村 保明

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… Alternative Names

TAMURA Yasuaki  田村 保明

田村 保明  タムラ ヤスアキ

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Researcher Number 80322329
Other IDs
External Links
Affiliation (Current) 2025: 札幌医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help 2024: 札幌医科大学, 医学部, 客員教授
2016: 北海道大学, 産学・地域協働推進機構, 特任教授
2014 – 2015: 北海道大学, フード&メディカルイノベーション推進本部, 特任教授
2014: 北海道大学, その他部局等, その他
2014: 北海道大学, フード&メディカルイノーべーション推進本部, 特任教授 … More
2014: 北海道大学, 先端生命科学研究院, 特任教授
2013: 北海道大学, 先端生命科学研究科(研究院), その他
2013: 北海道大学, 先端生命科学研究科(研究院), 特任教授
2013: 北海道大学, 大学院先端生命科学研究院, 特任教授
2004 – 2012: Sapporo Medical University, School of Medicine, Assistant Professor, 医学部, 講師
2004: 札幌医科大学, 医学部, 助教授
2002 – 2004: 札幌医科大学, 医学部, 助手
2000: 札幌医科大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Human pathology / Basic Section 49020:Human pathology-related / Experimental pathology / Biological Sciences
Except Principal Investigator
Human pathology / Medical Physics and Radiological Technology / Respiratory organ internal medicine / Biological Sciences / General surgery / Urology / Experimental pathology
Keywords
Principal Investigator
樹状細胞 / Hsp90 / HLA-A24 / 細胞障害性T細胞 / 乳がん / ORP150 / ジスルフィド結合 / 低酸素 / 細胞傷害性T細胞 / サバイビン … More / 熱ショック蛋白質 / 癌免疫療法 / 膵臓がん / 脂肪細胞 / 筋線維芽細胞 / 腫瘍微小環境 / endocytosis / receptor / cross-presentation / dendritic cell / 獲得免疫 / エンドサイトーシス / 受容体 / クロスプレゼンテーション / Heat shock protein / cytotoxic T cell / tumor antigen / Survivin / 細胞傷害性リンパ球 / 腫瘍抗原 / 乳癌 / 大腸癌 / 膵臓癌 / がん抗原ペプチド / 上皮間葉転換 / がん幹細胞 / 免疫抑制性細胞 / 細胞周囲環境 / VEGFA / MHC クラスI / G-CSF / 腫瘍免疫 / PDI / ERO1-α / MHC クラスI分子 / がんワクチン / 分子標的治療 / 酸化酵素 / MHC class I / 低酸素環境 / S-S結合 / ストレス蛋白質 / 抗原提示 / 宿主免疫監視機構 / MHCクラスII / MHCクラスI / ERO1 / 分子病理 / 癌抗原 / 抗原提示細胞 / シグナルシークエンス / DNAワクチン / Hsp90, 癌抗原 / トランスジェニックマウス / 抗原ペプチド / SYT-SSX … More
Except Principal Investigator
SYT-SSX / 抗原ペプチド / CTL / HSP90 / CD8 CTL / gp96 / survivin / サバイビン / 癌ワクチン / 癌免疫 / 腫瘍抗原 / 分子シャペロン / 熱ショック蛋白質 / がん凍結治療 / 凍結療法 / 悪性腫瘍 / Cryo-immunology / 凍結治療 / がん / IVR / Cryotherapy / HAD inhibitor / epigenetics / immune escape / HLA class I down regulation / cancer vaccine / 病理標本 / CIITA / II / MHC I / 癌抗原ペプチドワクチン / mAb / 免疫治療 / β2ミクログロブリン / HDAC / HLAクラス1 / ヒト癌免疫治療 / エスケープ / HDAC阻害剤 / エピジェネティクス / 免疫エスケープ / HLAクラスI / 癌ペプチドワクチン / tumor rejection / immuno-gene therapy / heat shock protein / 癌拒絶 / 免疫遺伝子治療 / 熱ショック融合蛋白質 / Bioinformatics / autologous tumor / clinical trials / peptide vaccines / tumor antigens / HLA-DR8 / リカバリン / ヒト癌抗原 / hsc 70 / 癌抗原処理提示 / 臨床試験 / 肉腫 / PBF / HLA-A24 / 骨肉腫抗原遺伝子 / 胃癌抗原遺伝子 / 癌抗原ペプチド / バイオインフォマティクス / 自家癌 / 第1相臨床試験 / ペプチドワクチン / 癌抗原 / side population / 幹細胞 / 免疫 / 膵 / 癌 / 腎移植 / 免疫制御・移植免疫 / Toll様受容体 / LPS / CpG / 形質細胞様樹状細胞 / TLR / Hsp72 / Hsp90 / 免疫賦活剤 / 樹状細胞 / クロスプレゼンテーション / 細胞障害性T細胞 / 自然免疫 / がんペプチドワクチン / CIC / CSC / CSC/CIC / SP法 / 分子標的 / 癌幹細胞 / 分子病理 / プロテアソーム / SPR / アミノ酸 / MHCクラスI / 結合モチーフ / ペプチド / HSP70 Less
  • Research Projects

    (16 results)
  • Research Products

    (161 results)
  • Co-Researchers

    (28 People)
  •  新規腫瘍関連筋脂肪細胞 (CAMA)の腫瘍進展における役割と治療標的の可能性Principal Investigator

    • Principal Investigator
      田村 保明
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Sapporo Medical University
  •  Cryo-immunology; booster effects of cryotherapy on the anti-tumor immune response

    • Principal Investigator
      Saito Hiroya
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical Physics and Radiological Technology
    • Research Institution
      Center for Clinical and Biomedical Research, Sapporo Higashi Tokushukai Hospital
  •  The development of combined cancer therapy targeting hypoxic microenvironmentPrincipal Investigator

    • Principal Investigator
      TAMURA Yasuaki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Hokkaido University
      Sapporo Medical University
  •  腎移植拒絶反応におけるHSP90の関与についての研究

    • Principal Investigator
      田中 俊明
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Sapporo Medical University
  •  Developing a novel vaccine therapy targeting cancer stem cells

    • Principal Investigator
      HIRATA Koichi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      Sapporo Medical University
  •  Potentiation of cancer immunotherapy using spatiotemporal regulation of heat shock protein-TLR ligand complex

    • Principal Investigator
      MATSUZAKI Junichi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Sapporo Medical University
  •  Molecular immunopathology of human cancer stem cell

    • Principal Investigator
      SATO Noriyuki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Human pathology
    • Research Institution
      Sapporo Medical University
  •  Hypoxia-inducible ERO1-α acts as a member of pre-peptide loading complex and regulates immune responses in the context of MHC class I and class II moleculesPrincipal Investigator

    • Principal Investigator
      TAMURA Yasuaki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Sapporo Medical University
  •  Induction of tumor antigen-specific CTL by Hsp90-antigen fusion DNA vaccinePrincipal Investigator

    • Principal Investigator
      TAMURA Yasuaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Sapporo Medical University
  •  Identification of Hsp90-specific receptor expressed on human dendritic cells and its application for cancer immunothearpyPrincipal Investigator

    • Principal Investigator
      TAMURA Yasuaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Sapporo Medical University
  •  Immune response and escape in human cancers

    • Principal Investigator
      SATO Noriyuki
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Human pathology
    • Research Institution
      Sapporo Medical University
  •  70hscの基質抗原ペプチド結合モチーフ解析

    • Principal Investigator
      SATO Noriyuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Sapporo Medical University
  •  Development of novel antitumor immunogenetherapy using artificial cancer antigen-secreting tumors.Principal Investigator

    • Principal Investigator
      TAMURA Yasuaki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Sapporo Medical University
  •  Cellular immunotherapy and immune-gene therapy by heat shock protein gp96 and dendritic cells

    • Principal Investigator
      YAMAZAKI Koichi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  熱ショック蛋白質を用いた癌免疫療法の臨床応用Principal Investigator

    • Principal Investigator
      田村 保明
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Sapporo Medical University
  •  Human cancer vaccines

    • Principal Investigator
      SATO Noriyuki
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Sapporo Medical University

All 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

  • [Book] 分子標的薬熱ショック蛋白質(heat shock protein; HSP)系2012

    • Author(s)
      田村保明, 齋藤慶太, 佐藤昇志
    • Publisher
      日本臨床
    • Data Source
      KAKENHI-PROJECT-23590427
  • [Book] Cancer, Immunology and Photonics Science. Optical Devices and Systems, Biomedical and Green Technologies2010

    • Author(s)
      Noriyuki Sato, Yoshihiko Hirohashi, Tomohide Tsukahara, Shingo Ichimiya, Yasuaki Tamura and Toshihiko Torigoe
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Book] SPを用いた免疫増強とHLA消失による免疫回避医学のあゆみ2008

    • Author(s)
      九冨五郎、田村保明
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Book] 熱ショック蛋白質による免疫制御と癌ワクチン開発、がんの温熱免疫療法2008

    • Author(s)
      田村保明
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Book] 熱ショック蛋白質による免疫制御と癌ワクチン開発.2008

    • Author(s)
      田村保明
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Book] Heat Shock Proteins in Cancer2007

    • Author(s)
      Tamura, Y., et. al.
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Book] 抗原クロスプレゼンテーションの新機軸一抗原提示経路における初期エンドソームの重要性 : 免疫エンドソームの提唱2007

    • Author(s)
      田村保明、九富五郎、佐藤昇志
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Book] Piloting of Exogenous Antigen into Cross-Presentation Pathway by Heat Shock Proteins In Heat Shock Proteins in Cancer2007

    • Author(s)
      Tamura Y., Kutomi G., Torigoe T., Sato N
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Book] Heat Shock Proteins in Biology and Medicine2006

    • Author(s)
      Tamura Y., et al.
    • Total Pages
      661
    • Publisher
      Research Signpost (India)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590309
  • [Book] Heat Shock Proteins in Biology and Medicine2006

    • Author(s)
      Tamura, Y. et al.
    • Publisher
      Extracellular heat shock proteins in immune response : A guide for cross-presentation.
    • Data Source
      KAKENHI-PROJECT-16209013
  • [Book] Heat Shock Proteins in Biology and Medicine2006

    • Author(s)
      Tamura, Y.
    • Total Pages
      12
    • Publisher
      Clingle Co. Ltd
    • Data Source
      KAKENHI-PROJECT-17590309
  • [Book] Heat Shock Proteins in Biology and Medicine2006

    • Author(s)
      Tamura, Y. et al.
    • Publisher
      Extracellular heat shock proteins in immune response : A euide for cross-presentation.
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209013
  • [Book] Annual Review 免疫2006

    • Author(s)
      大浦 淳, 田村保明, 佐藤昇志
    • Total Pages
      6
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-17590309
  • [Book] Annual Review免疫2005;熱ショック蛋白質(HSP)-ペプチド複合体による新しいMHCクラスI抗原提示経路(佐藤昇志、他編集)2005

    • Author(s)
      田村保明, 佐藤昇志
    • Total Pages
      8
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-15659097
  • [Book] Annual Review免疫2005;熱ショック蛋白質(HSP)-ペプチド複合体による新しいMHCクラスI抗原提示経路(佐藤昇志, 他編集)2005

    • Author(s)
      田村保明, 佐藤昇志
    • Total Pages
      8
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-16209013
  • [Book] Annual Review免疫2005;熱ショック蛋白質(HSP)-ペプチド複合体による新しいMHCクラスI抗原提示経路(佐藤昇志, 他編集)2005

    • Author(s)
      田村保明, 佐藤昇志
    • Total Pages
      8
    • Publisher
      中外医学社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12213116
  • [Book] Annual Review免疫2005;熱ショック蛋白質(HSP)-ペプチド複合体による新しいMHCクラスI抗原提示経路(佐藤昇志、他編集)2005

    • Author(s)
      田村保明, 佐藤昇志
    • Total Pages
      8
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-12213116
  • [Book] Annual Review免疫2005;熱ショック蛋白質(HSP)-ペプチド複合体による新しいMHCクラスI抗原提示経路2004

    • Author(s)
      田村保明
    • Total Pages
      8
    • Publisher
      中外医学社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590353
  • [Book] 分子シャペロンによる免疫制御とがんワクチン開発、分子医学

    • Author(s)
      田村保明
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Journal Article] Cancer-associated oxidoreductase ERO1-α drives the production of tumor-promoting myeloid-derived suppressor cells via oxidative protein folding.2015

    • Author(s)
      Tsutomu Tanaka, Toshimitsu Kajiwara, Toshihiko Torigoe, Yoshiharu Okamoto, Noriyuki Sato, Yasuaki Tamura
    • Journal Title

      J Immunology

      Volume: 194 Issue: 4 Pages: 2004-2010

    • DOI

      10.4049/jimmunol.1402538

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592, KAKENHI-PROJECT-26670305
  • [Journal Article] CpG-A stimulates Hsp72 secretion from plasmacytoid dendritic cells, facilitating cross-presentation.2015

    • Author(s)
      Tanaka T, Kajiwara T, Kutomi G, Kutomi G, Kurotaki T, Saito K, Kanaseki T, Tsukahara T, Hirohashi Y, Torigoe T, Hirata K, Okamoto Y, Sato N, Tamura Y.
    • Journal Title

      Immunol Lett

      Volume: 167 Issue: 1 Pages: 34-40

    • DOI

      10.1016/j.imlet.2015.06.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670305, KAKENHI-PROJECT-25293289
  • [Journal Article] Cancer-associated oxidase ERO1-α regulates the expression of MHC class I molecule via oxidative folding.2015

    • Author(s)
      Kazuharu Kukita, Yasuaki Tamura, Tsutomu Tanaka, Toshimitsu Kajiwara, Goro Kutomi, Keita Saito, Koichi Okuya, Akari Takaya, Takayuki Kanaseki, Tomohide Tsukahara, Yoshihiko Hirohashi, Toshihiko Torigoe, Tomohisa Furuhata, Koichi Hirata, Noriyuki Sato
    • Journal Title

      J Immunology

      Volume: 197 Issue: 10 Pages: 0-0

    • DOI

      10.4049/jimmunol.1303228

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24591978, KAKENHI-PROJECT-26670305, KAKENHI-PROJECT-25293289
  • [Journal Article] Phase I Clinical Study of Survivin-Derived Peptide Vaccine for Patients with Advanced Gastrointestinal Cancers.2015

    • Author(s)
      Satomi F, Shima H, Mizuguchi T, Torigoe T, Kutomi G, Kimura Y, Hirohashi Y, Tamura Y, Tsukahara T, Kanaseki T, Takahashi A, Asanuma H, Ito Y, Hayashi H, Sugita O, Sato N and Hirata K.
    • Journal Title

      Int J Cancer Clin Res

      Volume: 2

    • NAID

      40020774852

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24659592
  • [Journal Article] Heat shock protein 90 associates with Toll-like receptors 7/9 and mediates self-nucleic acid recognition in SLE.2015

    • Author(s)
      Saito K, Kukita K, Kutomi G, Okuya K, Asanuma H, Tabeya T, Naishiro Y, Yamamoto M, Takahashi H, Torigoe T, Nakai A, Shinomura Y, Hirata K, Sato N, Tamura Y.
    • Journal Title

      Eur. J Immunology

      Volume: 0 Issue: 7 Pages: 0-0

    • DOI

      10.1002/eji.201445293

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-26670305, KAKENHI-PUBLICLY-26116720, KAKENHI-PROJECT-15H04706, KAKENHI-PROJECT-25293289
  • [Journal Article] Expression of hepatocyte growth factor in prostate cancer may indicate a biochemical recurrence after radical prostatectomy.2015

    • Author(s)
      Nishida S, Hirohashi Y, Torigoe T., Nojima M, Inoue R, Kitamura H, Tanaka T, Asanuma H, Sato N, Masumori N.
    • Journal Title

      Anticancer Res

      Volume: 35 Pages: 413-418

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24659592
  • [Journal Article] Heat shock protein 90 targets a chaperoned peptide to the static early endosome for efficient cross-presentation by human dendritic cells2015

    • Author(s)
      Tsutomu Tanaka, Koichi Okuya, Goro Kutomi, Akari Takaya, Toshimitsu Kajiwara, Takayuki Kanaseki, Tomohide Tsukahara, Yoshihiko Hirohashi, Toshihiko Torigoe, Koichi Hirata, Yoshiharu Okamoto, Noriyuki Sato, Yasuaki Tamura
    • Journal Title

      Cancer Science

      Volume: 106 Issue: 1 Pages: 18-24

    • DOI

      10.1111/cas.12570

    • NAID

      120005593448

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467, KAKENHI-PROJECT-26670305, KAKENHI-PROJECT-25293289
  • [Journal Article] Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells.2014

    • Author(s)
      Morita R, Nishizawa S, Torigoe T, Takahashi A, Tamura Y, Tsukahara T, Kanaseki T, Sokolovskaya A, Kochin V, Kondo T, Hashino S, Asaka M, Hara I, Hirohashi Y, Sato N.
    • Journal Title

      Cancer Sci

      Volume: 105 Issue: 4 Pages: 389-395

    • DOI

      10.1111/cas.12362

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592, KAKENHI-PROJECT-24791467, KAKENHI-PROJECT-25462344
  • [Journal Article] Expression and function of FERMT genes in colon carcinoma cells.2013

    • Author(s)
      Kiriyama K, Hirohashi Y, Torigoe T, Kubo T, Tamura Y, Kanaseki T, Takahashi A, Nakazawa E, Saka E, Ragnarsson C, Nakatsugawa M, Inoda S, Asanuma H, Takasu H, Hasegawa T, Yasoshima T, Hirata K, Sato N
    • Journal Title

      Anticancer Res

      Volume: 33 Pages: 167-73

    • Data Source
      KAKENHI-PROJECT-24659592
  • [Journal Article] Human Endoplasmic Reticulum Oxidoreductin 1-α(hERO1-α) is a Novel Predictor for Poor Prognosis of Breast Cancer2013

    • Author(s)
      Kutomi G, Tamura Y, Tanaka T, Kajiwara T, Kukita K, Ohmura T, Shima H, Takamaru T, Satomi F, Suzuki Y, Torigoe T, Sato N, Hirata H
    • Journal Title

      Cancer Sci.

      Volume: 104 Issue: 8 Pages: 1091-6

    • DOI

      10.1111/cas.12177

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592
  • [Journal Article] Expression of ECRG4 is associated with lower proliferative potential of esophageal cancer cells2013

    • Author(s)
      Matsuzaki J, Torigoe T, Hirohashi Y, Tamura Y, Asanuma H, Nakazawa E, Saka E, Yasuda K, Takahashi S, Sato N
    • Journal Title

      Pathol Int.

      Volume: 63(8) Issue: 8 Pages: 391-7

    • DOI

      10.1111/pin.12079

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24659165
  • [Journal Article] Expression of ECRG4 is associated with lower proliferative potential of esophageal cancer cells.2013

    • Author(s)
      Matsuzaki J, Torigoe T, Hirohashi Y, Tamura Y, Asanuma H, Nakazawa E, Saka E, Yasuda K, Takahashi S, Sato N.
    • Journal Title

      Pathology International

      Volume: 63 Pages: 391-397

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590427
  • [Journal Article] Six-transmembrane epithelial antigen of the prostate-1 plays a role for in vivo tumor growth via intercellular communication.2013

    • Author(s)
      Yamamoto T, Tamura Y, Kobayashi J, Kamiguchi K, Hirohashi Y, Miyazaki A, Torigoe T, Asanuma H, Hiratsuka H, Sato N.
    • Journal Title

      Experimental Cell Research

      Volume: 319 Pages: 2617-2626

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590448
  • [Journal Article] Six-transmembrane epithelial antigen of the prostate-1 plays a role for in vivo tumor growth via intercellular communication2013

    • Author(s)
      Yamamoto T, Tamura Y, Kobayashi J, Kamiguchi K, Hirohashi Y, Miyazaki A, Torigoe T, Asanuma H, Hiratsuka H, Sato N
    • Journal Title

      Exp. Cell Res.

      Volume: 319 Issue: 17 Pages: 2617-29

    • DOI

      10.1016/j.yexcr.2013.07.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659901
  • [Journal Article] Immunotherapeutic benefit ofα-interferon (IFNα) in survivin2B-derived peptide vaccination for advanced pancreatic cancer patients2013

    • Author(s)
      Kameshima H, Tsuruma T, Kutomi G, Shima H, Iwayama Y, Kimura Y, Imamura M, Torigoe T, Takahashi A, Hirohashi Y, Tamura Y, Tsukahara T, Kanaseki T, Sato N, Hirata K
    • Journal Title

      Cancer Sci.

      Volume: 104 Issue: 1 Pages: 124-129

    • DOI

      10.1111/cas.12046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592
  • [Journal Article] Preferential expression of cancer/testis genes in cancer stem-like cells : proposal of a novel sub-category, cancer/testis/stem gene.2013

    • Author(s)
      Yamada R, Takahashi A, Torigoe T, Morita R, Tamura Y, Tsukahara T, Kanaseki T, Kubo T, Watarai K, Kondo T, Hirohashi Y, Sato N.
    • Journal Title

      Tissue Antigens.

      Volume: 81(6) Issue: 6 Pages: 428-34

    • DOI

      10.1111/tan.12113

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467
  • [Journal Article] Expression and function of FERMT genes in colon carcinoma cells2013

    • Author(s)
      Kiriyama, K., Hirohashi, Y., Torigoe, T., Kubo, T., Tamura, Y., Kanaseki, T., Takahashi, A., Nakazawa, E., Saka, E., Ragnarsson, C., Natatsugawa, M., Inoda, S., Asanima, H., Takasu, H., Hasegawa, T., Yasoshima, T, Hirata, K., Sato, N.
    • Journal Title

      Anticancer Res.

      Volume: 33 Pages: 167-173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590427
  • [Journal Article] DNA methyltransferase 1 is essential for initiation of the colon cancers2013

    • Author(s)
      Morita R,Hirohashi Y,Suzuki H, et al
    • Journal Title

      Experimental and Molecular Pathology

      Volume: 94 Issue: 2 Pages: 322-329

    • DOI

      10.1016/j.yexmp.2012.10.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115
  • [Journal Article] Highexpression of ALDH1 and SOX2 diffuse staining pattern of oral squamous cellcarcinomas correlates to lymph node metastasis.2013

    • Author(s)
      Michifuri Y, Hirohashi Y, Torigoe T,Miyazaki A, Kobayashi J, Sasaki T, FujinoJ, Asanuma H, Tamura Y, Nakamori K, Hasegawa T, Hiratsuka H, Sato N.
    • Journal Title

      Pathol Int.

      Volume: 62(10) Issue: 10 Pages: 684-9

    • DOI

      10.1111/j.1440-1827.2012.02851.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390388, KAKENHI-PROJECT-22592242, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24659901, KAKENHI-PROJECT-24792005
  • [Journal Article] New paradigm for intrinsic function of heat shock proteins as endogenous ligands in inflammation and innate immunity.2012

    • Author(s)
      Tamura Y, Torigoe T, Kutomi G, Hirata K, Sato N.
    • Journal Title

      Curr Mol Med.

      Volume: 12 Pages: 1198-1206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590427
  • [Journal Article] New paradigm for intrinsic function of heat shock proteins as endogenous ligands in inflammation and innate immunity.2012

    • Author(s)
      Tamura Y, Torigoe T, Kutomi G, Hirata K, Sato N
    • Journal Title

      Curr Mol Med.

      Volume: 12 Pages: 1198-1206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659592
  • [Journal Article] ECRG4 is a negative regulator of caspase-8-mediated apoptosis in human T-leukemia cells2012

    • Author(s)
      Matsuzaki J,Torigoe T,Hirohashi Y, Kamiguchi K,Tamura Y, Tsukahara T,Kubo T, Takahashi A, Nakazawa E,Saka E, Yasuda K,Takahashi S,Sato N.
    • Journal Title

      Carcinogenesis

      Volume: 33 Issue: 5 Pages: 996-1003

    • DOI

      10.1093/carcin/bgs118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J06539, KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22689041, KAKENHI-PROJECT-23590427
  • [Journal Article] Heat-shock proteins as endogenous ligands building a bridge between innate and adaptive immunity.2012

    • Author(s)
      Tamura Y, Torigoe T, Kukita K, Saito K, Okuya K, Kutomi G, Hirata K, Sato N.
    • Journal Title

      Immunotherapy

      Volume: 8 Issue: 8 Pages: 841-852

    • DOI

      10.2217/imt.12.75

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592
  • [Journal Article] New paradigm for intrinsic function of heat shock proteins as endogenous ligands in inflammation and innate immunity2012

    • Author(s)
      Tamura Y, Torigoe T, Kutomi G, Hirata K, Sato N
    • Journal Title

      Curr Mol Med

      Volume: 12 Pages: 1198-1206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590427
  • [Journal Article] N-propionyl-4-S-cysteaminylphenol induces apoptosis in B16F1cells and mediates tumor-specific T-cell immune responses in a mouse melanoma model.2012

    • Author(s)
      Ishii-Osai, Y.
    • Journal Title

      J. Dermatol. Sci.

      Volume: 67 Issue: 1 Pages: 51-60

    • DOI

      10.1016/j.jdermsci.2012.04.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300332, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24590448
  • [Journal Article] Heat shock protein 40 family, DNAJB8 is expressed in renal cancer stem-like cell, controls the tumor-initiating ability and can be a potent target of immunotherapy.2012

    • Author(s)
      Nishizawa, S., Mori, T., Hirohashi, Y., Torigoe, T., Tamura, Y., Kamiguchi, K., Takahashi, A., Kanaseki, T., Nakazawa, E., Asanuma, H., Sokolovskaya, A., Morita, R., Yamada, R., Fujii, R., Kondo, T., Hasegawa, T., Hara, I. and Sato, N.
    • Journal Title

      Cancer Res

      Volume: (in press) Issue: 11 Pages: 2844-54

    • DOI

      10.1158/0008-5472.can-11-3062

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24659165
  • [Journal Article] Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes2012

    • Author(s)
      Takahashi A, Torigoe T, Tamura Y, Kanaseki T, Tsukahara T, Sasaki Y, Kameshima H, Tsuruma T, Hirata K, Tokino T, Hirohashi Y, Sato N
    • Journal Title

      Cell Stress Chaperones

      Volume: 17 Issue: 6 Pages: 757-763

    • DOI

      10.1007/s12192-012-0348-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592, KAKENHI-PROJECT-24791467
  • [Journal Article] Human Endoplasmic Reticulum Oxidoreductin 1-Likeα(hERO1-Lα)のMHC class I分子発現制御と癌免疫療法に対する効果予測因子としての可能性.2012

    • Author(s)
      久木田和晴, 田村保明, 奥谷浩一, 齋藤慶太, 九冨五郎, 佐藤昇志, 平田公一.
    • Journal Title

      Jpn J Cancer Chemother

      Volume: 39 Pages: 1800-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659592
  • [Journal Article] New paradigm for intrinsic function of heat shock proteins as endogenous ligands in inflammation and innate immunity.2012

    • Author(s)
      Tamura Y, Torigoe T, Kutomi G, Hirata K, Sato N.
    • Journal Title

      Curr Mol Med.

      Volume: 12 Pages: 1198-1206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590448
  • [Journal Article] Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population2012

    • Author(s)
      Mori T, Nishizawa S, Hirohashi Y, Torigoe T, Tamura Y, Takahashi A, Kochin V, Fujii R, Toru K, Greene MI, Hara I, Sato N.
    • Journal Title

      Exp Mol Pathol

      Volume: 92 Pages: 27-32

    • URL

      http://dx.doi.org/10.1016/j.yexmp.2011.09.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Establishment of a monoclonal anti-pan HLA class I antibody suitable for immunostaining of formalin-fixed tissue : Unusually high frequency of down-regulation in breast cancer tissues2012

    • Author(s)
      Torigoe, T., Asanuma, H., Nakazawa. E., Tamura, Y., Hirohashi, Y., Yamamoto, E., Kanaseki, T., Hasegawa, T., Sato, N.
    • Journal Title

      Pathol Int

      Volume: 62 Issue: 5 Pages: 303-8

    • DOI

      10.1111/j.1440-1827.2012.02789.x

    • NAID

      10031185205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24659592
  • [Journal Article] Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population2012

    • Author(s)
      Takashi Mori, Satoshi Nishizawa, Yoshihiko Hirohashi, Toshihiko Torigoe, Yasuaki Tamura, Akari Takahashi, Vitaly Kochin, Reona Fujii, Kondo Toru, Mark I. Greene, Isao Hara, Noriyuki Sato
    • Journal Title

      Experimental and Molecular Pathology

      Volume: 92 Issue: 1 Pages: 27-32

    • DOI

      10.1016/j.yexmp.2011.09.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10F00121, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24659592
  • [Journal Article] The feasibility of Cep55/c10orf3 derived peptide vaccine therapy for colorectal carcinoma2011

    • Author(s)
      Inoda S, Morita R, Hirohashi Y, Torigoe T, Asanuma H, Nakazawa E, Nakatsugawa M, Tamura Y, Kamiguchi K, Tsuruma T, Terui T, Ishitani K, Hashino S, Wang Q, Greene MI, Hasegawa T, Hirata K, Asaka M, Sato N.
    • Journal Title

      Exp. Mol. Pathol

      Volume: 90 Pages: 55-60

    • URL

      http://dx.doi.org/10.1016/j.yexmp.2010.10.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Extracellular heat shock protein 90 plays a role in translocating chaperoned antigen from endosome to proteasome for generating antigenic peptide to be cross-presented by dendritic cells.2011

    • Author(s)
      Oura, J., Tamura, Y., Kamiguchi, K., Kutomi, G., Sahara, H., Torigoe, T., Himi, T., and Sato, N.
    • Journal Title

      Int. Immunol

      Volume: 23 Issue: 4 Pages: 223-237

    • DOI

      10.1093/intimm/dxq475

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590400, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-23390398, KAKENHI-PROJECT-23590427
  • [Journal Article] Tumor-Produced Secreted Form of Binding of Immunoglobulin Protein (BiP) elicits Antigen Specific Tumor Immunity.2011

    • Author(s)
      Tamura Y, et al.
    • Journal Title

      J Immunology

      Volume: 186 Pages: 4320-4330

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Journal Article] Tumor-Produced Secreted Form of Binding of Immunoglobulin Protein(BiP) elicits Antigen Specific Tumor Immunity2011

    • Author(s)
      Tamura Y, et al.
    • Journal Title

      J Immunology

      Volume: 186 Pages: 4325-4330

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Journal Article] Tumor-Produced Secreted Form of Binding of Immunoglobulin Protein Elicits Antigen-Specific Tumor Immunity.2011

    • Author(s)
      Tamura Y, Hirohashi Y, Kutomi G, Nakanishi K, Kamiguchi K, Torigoe T, Sato N.
    • Journal Title

      J. Immunol

      Volume: 186 Issue: 7 Pages: 4325-4330

    • DOI

      10.4049/jimmunol.1004048

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590400, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235, KAKENHI-PROJECT-23590427
  • [Journal Article] Cytotixic T lymphocytes efficiently recognize human colon cancer stem-like cells2011

    • Author(s)
      Inoda, S., Hirohashi, Y., Torigoe, T., Takahashi, A., Morita, R., Nakatsugawa, M., Nishizawa, S., Tamura, Y., Tsuruma, T., Terui, T., Ishitani, K., Hirata, K. and Sato, N.
    • Journal Title

      Am. J. Pathol

      Volume: 178 Pages: 1805-1813

    • URL

      http://dx.doi.org/10.1016/j.ajpath.2011.01.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Immunogenic enhancement and clinical effect by type-I interferon of anti-apoptotic protein, survivin-derived peptide vaccine, in advanced colorectal cancer patients2011

    • Author(s)
      Kameshima, H., Tsuruma, T., Torigoe, T., Takahashi, A., Hirohashi, Y., Tamura, Y., Tsukahara, T., Ichimiya, S., Kanaseki, T., Iwayama, Y., Sato, N., Hirata, K.
    • Journal Title

      Cancer Sci

      Volume: 102 Issue: 6 Pages: 1181-1187

    • DOI

      10.1111/j.1349-7006.2011.01918.x

    • NAID

      10029294487

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235, KAKENHI-PROJECT-22689041, KAKENHI-PROJECT-23590405, KAKENHI-PROJECT-23590427
  • [Journal Article] Autoantibody against hypoxia-inducible factor prolyl hydroxylase-3 is a potential serological marker for renal cell carcinoma2011

    • Author(s)
      Tanaka, T., Kitamura, H., Torigoe, T., Hirohashi, Y., Masumori, N., Sato, N. and Tsukamoto, T.
    • Journal Title

      J. Cancer Res. Clin. Oncol

      Volume: 137 Issue: 5 Pages: 789-794

    • DOI

      10.1007/s00432-010-0940-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235, KAKENHI-PROJECT-22791477
  • [Journal Article] Tumor-Produced Secreted Form of Binding of Immunoglobulin Protein Elicits Antigen-Specific Tumor Immunity. Selected paper in "In thia issue" of the Journal2011

    • Author(s)
      Tamura Y., Sato, N., et al.
    • Journal Title

      J.Immunol.

      Volume: 186 Pages: 4325-4330

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] SOX2 is expressed in stem-like cells of human lung adenocarcinoma and augments the tumor-initiating potential2011

    • Author(s)
      Nakatsugawa, M., Takahashi, A., Hirohashi, Y., Torigoe, T., Inoda, S., Asanuma, H., Tamura, Y., Hasegawa, T., Takahashi, H., and Sato, N.
    • Journal Title

      Lab Invest.

      Volume: 91 Issue: 12 Pages: 1796-1804

    • DOI

      10.1038/labinvest.2011.140

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235, KAKENHI-PROJECT-23590427
  • [Journal Article] Extracellular Heat Shock Protein 90 Translocates Chaperoned Antigen from Endosome to Proteasome for Generating Antigenic Peptide to be Cross-presented by Dendritic Cells2011

    • Author(s)
      Oura J, Tamura Y
    • Journal Title

      Int Immunol

      Volume: 23 Pages: 223-237

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Journal Article] Cytotixic T lymphocytes efficiently recognize human colon cancer stem-like cells2011

    • Author(s)
      Inoda, S., Hirohashi, Y., Torigoe, T., Takahashi, A., Morita, R., Nakatsugawa, M., Nishizawa, S., Tamura, Y., Tsuruma, T., Terui, T., Ishitani, K., Hirata, K. and Sato, N.
    • Journal Title

      Am. J. Pathol.

      Volume: 178 Issue: 4 Pages: 1805-1813

    • DOI

      10.1016/j.ajpath.2011.01.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22390278, KAKENHI-PROJECT-23590427
  • [Journal Article] Extracellular Heat Shock Protein 90 Translocates Chaperoned Antigen from Endosome to Proteasome for Generating Antigenic Peptide to be Cross-presented by Dendritic Cells.2011

    • Author(s)
      Oura J, Tamura Y, et al.
    • Journal Title

      International Immunology

      Volume: 23 Pages: 223-237

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Journal Article] Comparison of speedy PCR-ssp method and serological typing of hla-a24 for Japanese cancer patients.2011

    • Author(s)
      Nakatsugawa M, Hirohashi Y, Torigoe T, Inoda S, Kiriyama K, Tamura Y, Sato E, Takahashi H, Sato N.
    • Journal Title

      J Immunoassay Immunochem

      Volume: 32 Issue: 2 Pages: 93-102

    • DOI

      10.1080/15321819.2010.543219

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235, KAKENHI-PROJECT-23590427
  • [Journal Article] Immune response against tumor antigens expressed on human cancer stem-like cells/tumor-initiating cells2010

    • Author(s)
      Hirohashi, Y., Torigoe, T., Inoda, S., Takahashi, A., Morita, R., Nishizawa, S., Tamura, Y., Suzuki, H., Yoyota, M. Sato, N.
    • Journal Title

      Immunotherapy

      Volume: 2 Pages: 201-211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Melanoma-targeted chemo-thermo-immuno(CTI)-therapy using N-propionyl-4-S-cysteaminylphenol-m agnetite nanoparticles elicits CTL response via heat shock protein-peptide complex release2010

    • Author(s)
      Sato A, Tamura Y, Sato N, Yamashita T, Takada T, Sato M, Osai Y, Okura M, Ono I, Ito A, Honda H, Wakamatsu K, Ito S, Jimbow K.
    • Journal Title

      Cancer Sci

      Volume: 101 Issue: 9 Pages: 1939-1946

    • DOI

      10.1111/j.1349-7006.2010.01623.x

    • NAID

      10027831209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-22659075
  • [Journal Article] Spatiotemporal regulation of heat shock protein 90-chaperoned self-DNA and CpG-oligodeoxynucleotide for type I IFN induction via targeting to static early endosome2010

    • Author(s)
      Okuya, K., Tamura, Y., Saito, K., Kutomi, G., Torigoe, T., Hirata, K., Sato, N.
    • Journal Title

      J. Immunol

      Volume: 184 Issue: 12 Pages: 7092-7099

    • DOI

      10.4049/jimmunol.1000490

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] Spatiotemporal regulation of heat shock protein 90-chaperoned self-DNA and CpG-oligodeoxynucleotide for type-I interferon induction via targeting to static early endosome2010

    • Author(s)
      Okuya K., Tamura Y, Saito K, Kutomi G, Torigoe T, Hirata K, Sato N.
    • Journal Title

      J Immunol

      Volume: 15(184) Pages: 7092-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Journal Article] Melanoma-targeted chemo-thermo-immuno (CTI)-therapy using N-propionyl-4-S-cysteaminylphenol-magnetite nanoparticles elicits CTL response via heat shock protein-peptide complex release.2010

    • Author(s)
      Sato A, Tamura Y, et al.
    • Journal Title

      Cancer Science

      Volume: 101 Pages: 1939-1946

    • NAID

      10027831209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Journal Article] Human leukocyte antigen class I down-regulation in muscle-invasive bladder cancer : Its association with clinical characteristics and survival after cystectomy2009

    • Author(s)
      Homma, I., Kitamura, H., Torigoe, T., Tanaka, T., Sato, E., Hirohashi, Y., Masumori, N., Sato, N. and Tsukamoto, T.
    • Journal Title

      Cancer Sci

      Volume: 100 Issue: 12 Pages: 2331-2334

    • DOI

      10.1111/j.1349-7006.2009.01329.x

    • NAID

      10027198144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer2009

    • Author(s)
      Honma, I., Torigoe, T., Hirohashi, Y., Kitamura, H., Sato, E., Masumori, N., Tamura, Y., Tsukamoto, T., Sato, N.
    • Journal Title

      J. Transl. Med

      Volume: 7 Issue: 1 Pages: 103-110

    • DOI

      10.1186/1479-5876-7-103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] A novel spliced form of a lens protein as a novel lung cancer antigen2009

    • Author(s)
      Nakatsugawa, M. Hirohashi, Y., Torigoe, T., Asanuma, H., Takahashi, A., Inosa, S., Kiriyama, K., Nakazawa, E., Harada, K., Takasi, H., Tamura, Y., Kamiguchi, K., Shijubo, N., Honda, R., Nomura, N., Hasegawa, T., Takahashi, H. and Sato, N.
    • Journal Title

      Cancer Sci

      Volume: 100 Issue: 8 Pages: 1485-1493

    • DOI

      10.1111/j.1349-7006.2009.01187.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] Targeting to Static Endosome is Required for Efficient Cross-Presentation of ER-resident Oxygen Regulated Protein 150-Peptide Complexes2009

    • Author(s)
      Kutomi G, Tamura Y.
    • Journal Title

      J Immunol

      Volume: 183 Pages: 5861-5869

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Journal Article] Clonal diversity of cytotoxic T lymphocytes that recognize autologous oral squamous cell carcinoma2009

    • Author(s)
      Kobayashi, J., Torigoe, T., Hirohashi, Y., Tamura, Y., Kamiguchi, K., Miyazaki, A., Yamaguchi, A., Yamamoto, T., Hariu, H., Hiratsuka, H. and Sato, N.
    • Journal Title

      Hum Immunol

      Volume: 70 Pages: 89-95

    • URL

      http://dx.doi.org/10.1016/j.humimm.2008.11.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Wild-type AIRE cooperates with p63 in HLA class II expression of medullary thymic stroma cells.2009

    • Author(s)
      Tonooka, A., Kubo, T., Ichimiya, S., Tamura, Y., Ilmarinen, T., Ulmanen, I., Kimura, S., Yokoyama, S., Takano, Y., Kikuchi, T. and Sato, N.
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 379 Pages: 765-770

    • URL

      http://dx.doi.org/10.1016/j.bbrc.2008.12.123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Cep55/c10orf3, a tumor antigen derived from a centrosome residing protein in breast carcinoma2009

    • Author(s)
      Inoda, S., Hirohashi, Y., Torigoe, T., Nakatsugawa, M., Kiriyama, K., Harada, K., Takasu, H., Tamura, Y., Kamiguchi, K., Asanuma, H., Tsuruma, T., Terui, T., Ishitani, K., Ohmura, T., Hasegawa, T., Hirata, K. and Sato, N.
    • Journal Title

      J. Immunother

      Volume: 32 Pages: 474-485

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] 熱ショック蛋白質を用いた癌免疫2009

    • Author(s)
      田村保明
    • Journal Title

      実験医学 27

      Pages: 2201-2205

    • Data Source
      KAKENHI-PROJECT-21590400
  • [Journal Article] Establishment of shared antigen reactive cytotixic T lymphocytes using co-stimulatory molecule introduced autologous cancer cells2009

    • Author(s)
      Hirohashi, Y., Torigoe, T., Hirai, I., Tamura, Y., Nakatsugawa, M., Inoue, Y., Kanaseki, T., Kamiguchi, K., Ikeda, H., Sasaki, A., Yamanaka, N. and Sato, N.
    • Journal Title

      Exp. Mol. Pathol

    • URL

      http://dx.doi.org/10.1016/j.yexmp.2009.09.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Polyamine compound deoxyspergualin inhibits heat shock protein-induced activation of immature dendritic cells2009

    • Author(s)
      Sugawara T, Torigoe T, Tamura Y, Kamiguchi K, Nemoto K, Oguro H, Sato N
    • Journal Title

      Cell Stress Chaperones 14(2)

      Pages: 133-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Journal Article] Heat shock proteins and immunity : application of hyperthermia for immunomodulation2009

    • Author(s)
      Torigoe, T., Tamura, Y., Sato, N.
    • Journal Title

      Int. J. Hyperthermia

      Volume: 25 Issue: 8 Pages: 610-616

    • DOI

      10.3109/02656730903315831

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] Targeting to static endosome is required for efficient cross-presentation of endoplasmic reticulum-resident oxygen regulated protein 150(ORP150)-peptide complexes2009

    • Author(s)
      Kutomi, G., Tamura, Y., Okuya, K., Hirohashi, Y., Kamiguchi, K., Saito, K., Torigoe, T., Ogawa, S., Hirata, K. and Sato, N.
    • Journal Title

      J. Immunol

      Volume: 183 Issue: 9 Pages: 5861-5869

    • DOI

      10.4049/jimmunol.0803768

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] Growth inhibition of re-challenge B16 melanoma transplant by conjugates of melanogenesis substrate and magnetite nanoparticles as the basis for developing melanoma-targeted chemo-thermo-immunotherapy2009

    • Author(s)
      Takada, T., Yamashita, T., Sato, M., Sato, A., Ono, I., Tamura, Y., Sato, N., Miyamoto, A, Ito, A., Honda, H., Wakamstu, K., Oto, S., Jimbow, K.
    • Journal Title

      J. Biomed. Biothechnol

      Volume: 2009 Issue: 1 Pages: 457936-457936

    • DOI

      10.1155/2009/457936

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Polyamine compound deoxyspergualin inhibits heat shock protein-induced activation of immature dendritic cells2009

    • Author(s)
      Sugawara, A., Torigoe, T., Tamura, Y., Kamiguchi, K., Nemoto, K., Oguro, H., Sato, N.
    • Journal Title

      Cell Stress Chaperone

      Volume: 14 Issue: 2 Pages: 133-139

    • DOI

      10.1007/s12192-008-0064-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] N-propionyl-cysteaminylphenol-magn etite conjugate(NPrCAP/M) is a nanoparticle for the targeted growth suppression of melanoma cells2009

    • Author(s)
      Sato, M., Yamashita, T., Ohkura, M., Osai, Y., Sato, A., Takada, T., Matsusaka, H., Ono, I., Tamura, Y., Sato, N., Sasaki, Y., Ito, A., Honda, H., Wakamastu, K., Ito, S. and Jimbow, K.
    • Journal Title

      J. Invest. Dermatol

      Volume: 129 Issue: 9 Pages: 2233-2241

    • DOI

      10.1038/jid.2009.39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Molecular pathologic approaches to human tumor immunology2009

    • Author(s)
      Sato, N., Hirohashi, Y., Tsukahara, T., Kikuchi, T., Sahara, H., Kamiguchi, K., Ichimiya, S., Tamura, H. and Torigoe, T.
    • Journal Title

      Pathol. Int

      Volume: 59 Issue: 4 Pages: 205-217

    • DOI

      10.1111/j.1440-1827.2009.02353.x

    • NAID

      10027379604

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] Clonal diversity of cytotxic T lymphocytes that recognize autologous oral squamouscell carcinoma2009

    • Author(s)
      Kobayashi J, Hirohashi Y, Torigoe T, Michifuri Y, Yamamoto T, Tamura Y, Kamiguchi L, Miyazaki A, Yamaguchi A, Hariu, H, Hiratsuka H, Sato N
    • Journal Title

      Hum Immunol 70(2)

      Pages: 89-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Journal Article] Phase I clinical study of anti-apoptosis protein survivin-derived peptide vaccination for patients with advanced or recurrent urothelial cancer2009

    • Author(s)
      Honma, I., Kitamura, H., Torigoe, A. Takahashi, T., Tanaka, T., Sato, E., Hirohashi, Y., Masumori, N., Tsukamoto, T., Sato, N.
    • Journal Title

      Cancer Immunol. Immunother

      Volume: 58 Issue: 11 Pages: 1801-1807

    • DOI

      10.1007/s00262-009-0691-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] Immunotherapy with dendritic cells pulsed with tumor-derived gp96 against murine lung cancer is effective through immune response of CD8+ cytotoxic T lymphocytes and natural killer cells2008

    • Author(s)
      Shinagawa N, Yamazaki K, Tamura Y, Imai A, Kikuchi E, Yokouchi H, Hommura F, Oizumi S, Nishimura M
    • Journal Title

      Cancer Immunol Immunother 57(2)

      Pages: 165-174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Journal Article] Identification of HLA-A24-restricted epitopes with high affinities to Hsp70 using peptide arrays2008

    • Author(s)
      Okochi M, Hayashi H, Ito A, Kato R, Tamura Y, Sato N, Honda H
    • Journal Title

      J Biosci Bioeng 105(3)

      Pages: 198-203

    • NAID

      110006632549

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Journal Article] Down-regulation of HLA class I antigen is an independent prognostic factor for clear cell renal cell carcinoma.2007

    • Author(s)
      Kitamura, H. et al.
    • Journal Title

      J.Urol. 177

      Pages: 1269-1272

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209013
  • [Journal Article] Extracellular heat shock proteins(eHSPs)pilot exogenous antigen into cross-presentation pathway: A superguide from extracellular world to intracellular tour.2007

    • Author(s)
      Tamura, Y., et. al.
    • Journal Title

      Annals Cancer Res. and Therapy 15

      Pages: 41-49

    • NAID

      130000119680

    • Data Source
      KAKENHI-PROJECT-19590357
  • [Journal Article] Efficient cross-presentation by heat shock protein 90-peptide complex-loaded dendritic cells via an endosomal pathway.2007

    • Author(s)
      Kurotaki T., Y.Tamura, et al.
    • Journal Title

      J. Immunology (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590309
  • [Journal Article] Extracellular heat shock proteins(eHSPs)pilot exogenous antigen into cross-presentation pathway : A superguide from extracellular world to intracellular tour2007

    • Author(s)
      Tamura, Y. et.al.
    • Journal Title

      Annals Cancer Res. and Therapy 15

      Pages: 41-49

    • NAID

      130000119680

    • Data Source
      KAKENHI-PROJECT-19590357
  • [Journal Article] Down-regulation of HLA class I antigen is an independent prognostic factor for clear cell renal cell carcinoma.2007

    • Author(s)
      Kitamura, H. et al.
    • Journal Title

      J. Urol. 177

      Pages: 1269-1272

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209013
  • [Journal Article] Effect of human leukocyte antigen class 1 expression of tumor cells on outcome of intravesical instillation of bacillus Calmette-Guerin immunotherapy for bladder cancer.2006

    • Author(s)
      Kitamura, H. et al.
    • Journal Title

      Clin.Cancer Res. 12

      Pages: 4641-4644

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209013
  • [Journal Article] Cytosolic overexpression of p62 sequestosome 1 in neoplastic prostate tissue.2006

    • Author(s)
      Kitamura, H.
    • Journal Title

      Histopathology 48

      Pages: 157-161

    • Data Source
      KAKENHI-PROJECT-17590309
  • [Journal Article] Induction of Autologous CD4- and CD8-mediated T-cell Responses against Acute Lymphocytic Leukemia (ALL) Cell Line using Apoptotic Tumor Cell-loaded Dendritic Cells2006

    • Author(s)
      Hatakeyama N., Y.Tamura, et al.
    • Journal Title

      Exp. Hematol 34

      Pages: 197-207

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590309
  • [Journal Article] Effect of human leukocyte antigen class I expression of tumor cells on outcome of intravesical instillation of bacillus Calmette-Guerin immunotherapy for bladder cancer.2006

    • Author(s)
      Kitamura, H. et al.
    • Journal Title

      Clin. Cancer Res. 12

      Pages: 4641-4644

    • Data Source
      KAKENHI-PROJECT-16209013
  • [Journal Article] Expression and antigenicity of survivin, an inhibitor of apoptosis family member, in bladder cancer : implications for specific immunotherapy.2006

    • Author(s)
      Kitamura, H. et al.
    • Journal Title

      Urology 67

      Pages: 955-959

    • Data Source
      KAKENHI-PROJECT-16209013
  • [Journal Article] Effect of human leukocyte antigen class I expression of tumor cells on outcome of mtravesical instillation of bacillus Calmette-Guerm immunotherapy for bladder cancer.2006

    • Author(s)
      Kitamura, H. et al.
    • Journal Title

      Clin. Cancer Res. 12

      Pages: 4641-4644

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209013
  • [Journal Article] A calcium binding protein, S100A4, mediates T cell dependent cytotoxicity as a transformation-associated antigen.2005

    • Author(s)
      Kondo, N., Ichimiya, S., Tamura, Y., Tonooka, A., Koshiba, S., Torigoe, T., Kamiguchi, K., Takenaga, K., Sato, N.
    • Journal Title

      Microbiol.Immunol. 49

      Pages: 49-56

    • NAID

      10014377175

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213116
  • [Journal Article] A potent immunogenic general cancer vaccine that targets survivin, an inhibitor of apoptosis proteins2005

    • Author(s)
      Idenoue, S., Hirohashi, Y., Torigoe, T., Sato, Y., Tamura, Y., Hariu, H., Yamamoto, M., Kurotaki, T., Tsuruma, T., Asanuma, H., Kanaseki, T., Ikeda, H., Kashiwagi, K., Okazaki, M., Sasaki, K., Sato, T., Ohmura, T., Hata, F., Yamaguchi, K., Hirata, K., Sato, N.
    • Journal Title

      Clin. Cancer Res. 11

      Pages: 1474-82

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590353
  • [Journal Article] A potent immunogenic general cancer vaccine that targets survivin, an inhibitor of apoptosis proteins.2005

    • Author(s)
      Idenoue, S., Hirohashi, Y., Torigoe, T., Sato, Y., Tamura, Y., Hariu, H., Yamamoto, M., Kurotaki, T., Tsuruma, T., Asanuma, H., Kanaseki, T., Ikeda, H., Kashiwagi, K., Okazaki, M., Sasaki, K., Sato, T., Ohmura, T., Hata, F., Yamaguchi, K., Hirata, K., Sato, N.
    • Journal Title

      Clin.Cancer Res. 11

      Pages: 1474-82

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213116
  • [Journal Article] Aberrant expression and potency as a cancer immunotherapy target of IAP family, Livin/ML-IAP in Lung Cancer.2005

    • Author(s)
      Hariu, H., Hirohashi, Y., Torigoe, T., Tamura, Y., Aketa, K., Kitamura, H., Idenoue, S., Hariu, M., Kamiguchi, K., Mano, Y., Kanaseki, T., Tsukahara, T., Shijubo, N., Sato, N.
    • Journal Title

      Clin.Cancer Res. 11

      Pages: 1000-1009

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213116
  • [Journal Article] Aberrant expression and potency as a cancer immunotherapy target of IAP family, Livin/ML-IAP in Lung Cancer2005

    • Author(s)
      Harlu, H., Hirohashi, Y., Torigoe, T., Tamura, Y., Aketa, K., Kitamura, H., Idenoue, S., Hariu, M., Kamiguchi, K., Mano, Y., Kanaseki, T., Tsukahara, T., Shijubo, N., Sato, N.
    • Journal Title

      Clin. Cancer Res. 11

      Pages: 1000-1009

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590353
  • [Journal Article] Tumor- derived heat shock protein70-pulsed dendritic cells elicit tumor- specific cytotoxic T lymphocytes (CTLs) and tumor immunity.2004

    • Author(s)
      Ueda, G., Tamura, Y., Hirai, I., Kamigichi, K., Ichimiya, S., Torigoe, T., Hiratsuka, H., Sunakawa, H., Sato, N.
    • Journal Title

      Cancer Science 95

      Pages: 248-253

    • NAID

      10013721926

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213116
  • [Journal Article] Tumor-derived heat shock protein70-pulsed dendritic cells elicit tumor-specific cytotoxic T lymphocytes (CTLs) and tumor immunity2004

    • Author(s)
      Ueda, G., Tamura, Y., Hirai, I., Kamigichi, K., Ichimiya, S., Torigoe, T., Hiratsuka, H., Sunakawa, H., Sato, N.
    • Journal Title

      Cancer Sci. 95

      Pages: 248-253

    • NAID

      10013721926

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590353
  • [Journal Article] Phase I clinical study of anti-apoptosis protein, survivin-derived peptide vaccine therapy for patients with advanced or recurrent colorectal cancer.2004

    • Author(s)
      Tsuruma, T., Hata, F., Torigoe, T., Furuhata, T., Idenoue, S., Kurotaki, T., Yamamoto, M., Yagihashi, A., Ohmura, T., Yamaguchi, K., Katsuramaki, T., Yasoshima, T., Sasaki, K., Mizushima, Y., Minamida, H., Kimura, H., Akiyama, M., Hirohashi, Y., Asanuma, H., Tamura, Y., Shimozawa, K., Sato, N., Hirata, K.
    • Journal Title

      J.Translational Med. 2

      Pages: 19-29

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213116
  • [Journal Article] Phase I clinical study of anti-apoptosis protein, survivin-derived peptide vaccine therapy for patients with advanced or recurrent colorectal cancer2004

    • Author(s)
      Tsuruma, T., Hata, F., Torigoe, T., Furuhata, T., Idenoue, S., Kurotaki, T., Yamamoto, M., Yagihashi, A., Ohmura, T., Yamaguchi, K., Katsuramaki, T., Yasoshima, T., Sasaki, K., Mizushima, Y., Minamida, H., Kimura, H., Akiyama, M., Hirohashi, Y., Asanuma, H., Tamura, Y., Shimozawa, K., Sato, N., Hirata, K.
    • Journal Title

      J. Translational Med. 2

      Pages: 19-29

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590353
  • [Journal Article] GM-CSF gene-transduced tumor cells combined with tumor-derived gp96 inhibit tumor growth in mice.2003

    • Author(s)
      Kojima T, Yamazaki K, Tamura Y, Ogura S, Tani K, Konishi J, Shinagawa N, Kinoshita I, Hizawa N, Yamaguchi E, Dosaka-Akita H, Nishunura M.
    • Journal Title

      Hum Gene Ther 14

      Pages: 715-728

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590789
  • [Journal Article] Heat shock proteins; Chaperoning of innate and adaptive immunities.2003

    • Author(s)
      Tamura, Y., Sato, N.
    • Journal Title

      Jpn.J.Hyperthermic Oncology 19

      Pages: 131-139

    • NAID

      10029675612

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213116
  • [Journal Article] Chaperoning of innate and adaptive immunities.2003

    • Author(s)
      Tamura, Y., Sato, N.
    • Journal Title

      Jpn.J.Hyperthermic Oncology 19

      Pages: 131-139

    • Data Source
      KAKENHI-PROJECT-15659097
  • [Journal Article] GM-CSF gene-transduced tumor cells combined with tumor-derived gp96 inhibit tumor growth in mice2003

    • Author(s)
      Kojima T, Yamazaki K, Tamura Y, Ogura S, Tani K, Konishi J, Shinagawa N, Kinoshita I, Hizawa N, Yamaguchi, E, Dosaka-Akita H, Nishimura M.
    • Journal Title

      Human Gene Therapy, Hum Gene Ther 14

      Pages: 715-728

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590789
  • [Journal Article] DNA methyltransferase 1 is essential for maintenance of human colon cancer stem-like cells

    • Author(s)
      Morita, R., Hirohashi, Y., Torigoe, T., Takahashi, A., Saka, E., Asanuma, H., Suzuki, H., Tamura, H., Nakazawa, E., Ito-Inoda, S., Hashino, S., Hasegawa, T., Tokino, T., Toyota, M., Asaka, M. and Sato, N.
    • Journal Title

      Am J. Pathol.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Heat shock protein 90 governs self-nucleic acid recognition by Toll-like receptors

    • Author(s)
      Saito, K., Tamura, Y., Kukita, K., Kutomi, G., Okuya, K., Asanuma, H., Torigoe, T., Hirata, K., Sato, N.
    • Journal Title

      Nature

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Patent] 癌の検出方法、診断薬および診断キット並びに癌治療用医薬組成物2012

    • Inventor(s)
      田村保明、久木田和晴、佐藤昇志
    • Industrial Property Rights Holder
      札幌医科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-189224
    • Filing Date
      2012-08-29
    • Data Source
      KAKENHI-PROJECT-24659592
  • [Patent] インターフェロンα産生阻害剤2010

    • Inventor(s)
      田村保明、佐藤昇志、鳥越俊彦、齋藤慶太
    • Industrial Property Rights Holder
      田村保明、佐藤昇志、鳥越俊彦、齋藤慶太
    • Industrial Property Number
      2010-219422
    • Filing Date
      2010-09-29
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Patent] インターフェロンα産生阻害剤2010

    • Inventor(s)
      田村保明, 他
    • Industrial Property Rights Holder
      田村保明, 他
    • Industrial Property Number
      2010-219422
    • Filing Date
      2010-09-29
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Patent] 癌ワクチン2009

    • Inventor(s)
      佐藤昇志, 鳥越俊彦, 田村保明, 佐藤雄一郎, 清水佳隆
    • Industrial Property Rights Holder
      佐藤昇志, 鳥越俊彦, 田村保明, 佐藤雄一郎, 清水佳隆
    • Industrial Property Number
      2009-124041
    • Filing Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Patent] アレルギー性疾患の予防・治療薬。2007

    • Inventor(s)
      田村保明, 佐藤昇志他
    • Industrial Property Rights Holder
      北海道
    • Industrial Property Number
      2007-050811
    • Filing Date
      2007-02-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590309
  • [Patent] アレルギー性疾患の予防・治療薬2007

    • Inventor(s)
      田村保明, 佐藤昇志 他
    • Industrial Property Rights Holder
      北海道
    • Industrial Property Number
      2007-050811
    • Filing Date
      2007-02-28
    • Data Source
      KAKENHI-PROJECT-17590309
  • [Presentation] 腫瘍高発現性酸化酵素ERO1-αとがん幹細胞形質の維持2014

    • Author(s)
      田中 努、田村 保明、久木田 和晴、梶原 敏充、鳥越 俊彦、岡本 芳晴、佐藤 昇志
    • Organizer
      第103回日本病理学会
    • Place of Presentation
      広島国際会議場 (広島県)
    • Data Source
      KAKENHI-PROJECT-24590448
  • [Presentation] SVN-2Bペプチドがんワクチン療法:第Ⅰ相臨床試験”SUCCESS"から得た最新の知見2014

    • Author(s)
      島 宏彰、水口 徹、里見 蕗乃、九冨 五郎、信岡 隆幸、木村 康利、古畑 智久、亀嶋 秀和、高橋あかり、塚原 智英、金関 貴幸、廣橋 良彦、鶴間 哲弘、岩山 祐司、田村 保明、鳥越 俊彦、佐藤 昇志、平田 公一
    • Organizer
      第18回日本がん免疫学会総会
    • Place of Presentation
      ひめぎんホール(松山市)
    • Year and Date
      2014-07-31
    • Data Source
      KAKENHI-PROJECT-24659592
  • [Presentation] Enhanced expression of endoplasmic reticulum disulfide oxidase 1-α (ERO1-α) inhibits anti-tumor immune response.2013

    • Author(s)
      田中 努、田村 保明、久木田 和晴、梶原 敏充、鳥越 俊彦、岡本 芳晴、佐藤 昇志
    • Organizer
      日本癌学会
    • Place of Presentation
      パシフィコ横浜 (神奈川県)
    • Data Source
      KAKENHI-PROJECT-24590448
  • [Presentation] Tumor microenvironment and antitumor immunity2013

    • Author(s)
      田村 保明、鳥越 俊彦、佐藤 昇志
    • Organizer
      第102回日本病理学会
    • Place of Presentation
      ロイトン札幌 (北海道)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590448
  • [Presentation] Tumor microenvironment and antitumor immunity)2013

    • Author(s)
      田村保明, 鳥越俊彦, 佐藤昇志
    • Organizer
      第102回日本病理学会シンポジウム
    • Place of Presentation
      札幌
    • Year and Date
      2013-06-06
    • Data Source
      KAKENHI-PROJECT-23590427
  • [Presentation] 腫瘍に高発現する酸化酵素ERO1-αは、がん幹細胞形質の維持に関与する2013

    • Author(s)
      田中 努、田村 保明、久木田 和晴、梶原 敏充、鳥越 俊彦、岡本 芳晴、佐藤 昇志
    • Organizer
      第102回日本病理学会
    • Place of Presentation
      ロイトン札幌 (北海道)
    • Data Source
      KAKENHI-PROJECT-24590448
  • [Presentation] ERO1-αによるMHC class I分子発現制御と 癌免疫療法に対する効果予測因子としての可能性2012

    • Author(s)
      久木田和晴、田村保明, 斎藤慶太, 鳥越俊彦, 平田公一, 佐藤昇志
    • Organizer
      日本癌学会総会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-24590448
  • [Presentation] ERO1-αによるMHC class I分子発現制御と 癌免疫療法に対する効果予測因子としての可能性2012

    • Author(s)
      田村保明, 久木田和晴, 斎藤慶太, 鳥越俊彦, 平田公一, 佐藤昇志
    • Organizer
      日本臨床ストレス応答学会
    • Place of Presentation
      東京都
    • Data Source
      KAKENHI-PROJECT-24590448
  • [Presentation] Heat shock proteins act as endogenous enhancers building a bridge between innate immunity and adaptive immunity2012

    • Author(s)
      田村保明
    • Organizer
      第71回日本癌学会学術総会シンポジウム
    • Place of Presentation
      札幌
    • Year and Date
      2012-09-20
    • Data Source
      KAKENHI-PROJECT-23590427
  • [Presentation] ERO1-αによるMHC class I分子発現制御と 癌免疫療法に対する効果予測因子としての可能性2012

    • Author(s)
      田村保明, 久木田和晴, 斎藤慶太, 鳥越俊彦, 平田公一, 佐藤昇志
    • Organizer
      日本免疫学会総会
    • Place of Presentation
      神戸市
    • Data Source
      KAKENHI-PROJECT-24590448
  • [Presentation] Human endoplasmic reticulum oxidoreductase 1-like α (hERO1-Lα)governs expression of MHC class II molecules through redox state on the antigen presenting cells2011

    • Author(s)
      田村保明
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Presentation] Human endoplasmic reticulum oxidoreductase 1-likeα(hERO1-Lα) governs expression of MHC class II molecules through redox state on the antigen presenting cells2011

    • Author(s)
      田村保明
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Presentation] human endoplasmic reticulum oxidoreductase 1 like(hERO1-L)によるMHC class I分子の発現制御2011

    • Author(s)
      久木田和晴、田村保明
    • Organizer
      日本病理学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-04-28
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Presentation] Hypoxia-inducible human endoplasmic reticulum oxidoreductase 1-Lα(hEro1-Lα) regulates immune response of cancer cells via modulation of MHC class I expression2011

    • Author(s)
      久木田和晴、田村保明
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Presentation] human endoplasmic reticulum oxidoreductase 1 like (hERO1-L)によるMHC class I分子の発現制御2011

    • Author(s)
      久木田和晴、田村保明
    • Organizer
      日本病理学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-04-28
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Presentation] Stress Response Genes Expressed in Cancer Stem Cells-potent molecular targets for cancer therapy2011

    • Author(s)
      Toshihiko Torigoe, Hirohashi Yoshihiko, Yasuaki Tamura, Noriyuki Sato
    • Organizer
      The 5^<th> International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      Quebec City, Canada
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Presentation] Hypoxia-inducible human endoplasmic reticulum oxidoreductase 1-Lα (hErol-Lα) regulates immune response of cancer cells via modulation of MHC class I expression2011

    • Author(s)
      久木田和晴、田村保明
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Presentation] Spatiotemporal regulation of heat shock protein 90-chaperoned self-DNA and CpG-oligodeoxynucleotide for type-I interferon induction via targeting to static early endosome.2010

    • Author(s)
      Tamura Y.
    • Organizer
      14^<th> International Congress on Immunology
    • Place of Presentation
      神戸
    • Year and Date
      2010-08-23
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Presentation] 自然免疫内因性リガンドとしてのストレス蛋白質による自己免疫疾患病態制御2009

    • Author(s)
      田村保明
    • Organizer
      第37回日本臨床免疫学会
    • Place of Presentation
      東京
    • Year and Date
      2009-11-13
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Presentation] Targeting "immune"-competent endosome by heat shock proteins(HSPs)for enhancing cancer immunotherapeutic potential2009

    • Author(s)
      田村保明
    • Organizer
      日本癌学会(international symposium)
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Presentation] Development of HSP90-based cancer vaccine and its mechanism2009

    • Author(s)
      Tamura, Y., Okuya, K., Saito, K., Torigoe, T., Sato, N.
    • Organizer
      The 4th International Congress on Stress Responses in Biology and Medicine/The 4th Annual Meeting of the Biomedical Society for Stress Response
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Presentation] Targeting immune-competent endosome by heat shok proteins(HSPs) for enhancing cancer immunotherapeutic potential2009

    • Author(s)
      Tamura, Y., Sato, N.
    • Organizer
      第68回日本癌学会学術総会、Internarional Sessions
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Presentation] Development of HSP-based cancer vaccine and its mechanism2009

    • Author(s)
      田村保明
    • Organizer
      ストレス蛋白質国際学会CSSI2009
    • Place of Presentation
      札幌
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-21590400
  • [Presentation] HSP-抗原ペプチド複合体はstatic endosomeに誘導されることによって効率よくクロスプレゼンテーションされる2008

    • Author(s)
      田村保明
    • Organizer
      第3回臨床ストレス応答学会大会
    • Place of Presentation
      秋田
    • Year and Date
      2008-11-14
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Presentation] 樹状細胞を用いたがん免疫療法の確立にむけて ; 熱ショック蛋白質(HSP)によるシャペロン分子の時・空間的制御と免疫制御2008

    • Author(s)
      田村保明
    • Organizer
      第48回日本リンパ網内系学会総会シンポジウム3、樹状細胞研究の新展開と樹状細胞免疫療法の現状と将来
    • Place of Presentation
      札幌
    • Year and Date
      2008-06-13
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Presentation] 熱ショック蛋白質を用いた癌治療の確立に向けて : 熱ショック蛋白質によるシャペロン分子の時空間的制御と免疫制御2008

    • Author(s)
      田村保明
    • Organizer
      第48回日本リンパ網内系学会総会シンポジウム
    • Place of Presentation
      札幌市
    • Year and Date
      2008-06-13
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Presentation] 樹状細胞を用いたがん免疫療法2008

    • Author(s)
      田村保明
    • Organizer
      日本ハイパーサーミア学会総会シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2008-09-13
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Presentation] 熱ショック蛋白質を用いた癌抗原のターゲッティング2007

    • Author(s)
      田村保明
    • Organizer
      第68回日本癌学会総会シンポジウム、腫瘍免疫療法の進歩
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-14
    • Data Source
      KAKENHI-PROJECT-19590357
  • [Presentation] Heat shock protein 90 is involved in antibody-mediated rejection and is a potential target of anti-rejection therapy in kidney transplantation

    • Author(s)
      Toshiaki Tanaka, Hideki Ishida, Miyuki Furusawa, Yasuaki Tamura, Hiroshi Kitamura, Satoshi Takahashi, Naoya Masumori, Kazunari Tanabe, Noriyuki Sato and Taiji Tsukamoto
    • Organizer
      American Transplant Congress 2013
    • Place of Presentation
      アメリカ合衆国 シアトル
    • Data Source
      KAKENHI-PROJECT-24592448
  • [Presentation] 抗体関連型移植片拒絶反応におけるheat shock protein 90の関与

    • Author(s)
      田中俊明、前鼻健志、北村寛、高橋聡、舛森直哉 、石田英樹、田村保明
    • Organizer
      第390回日本泌尿器科学会北海道地方会
    • Place of Presentation
      旭川
    • Data Source
      KAKENHI-PROJECT-24592448
  • [Presentation] 腫瘍高発現性酸化酵素ERO1-αとがん幹細胞形質維持

    • Author(s)
      田中 努、田村 保明、久木田 和晴、梶原 敏充、鳥越 俊彦、岡本 芳晴、佐藤 昇志
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島市
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-24590448
  • [Presentation] Hsp90による核酸系自然免疫リガンドの時空間的制御と免疫応答増強効果

    • Author(s)
      田村保明
    • Organizer
      日本臨床ストレス応答学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23590427
  • [Presentation] 分泌型熱ショック蛋白質を用いた癌免疫療法

    • Author(s)
      田村保明
    • Organizer
      日本免疫学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590427
  • [Presentation] 腫瘍に高発現する酸化酵素ERO1-αは、がん幹細胞形質の維持に関与する

    • Author(s)
      田村 保明, 田中 努、梶原 敏充、鳥越 俊彦、岡本 芳晴、佐藤 昇志
    • Organizer
      第9回臨床ストレス応答学会
    • Place of Presentation
      岡山市
    • Year and Date
      2014-11-01 – 2014-11-02
    • Data Source
      KAKENHI-PROJECT-24590448
  • [Presentation] 腫瘍に高発現する酸化酵素ERO1-αは、腫瘍増殖環境を整える

    • Author(s)
      田中 努、田村 保明、梶原 敏充、鳥越 俊彦、岡本 芳晴、佐藤 昇志
    • Organizer
      第104回日本病理学会総会
    • Place of Presentation
      名古屋市
    • Year and Date
      2015-04-30 – 2015-05-02
    • Data Source
      KAKENHI-PROJECT-24590448
  • [Presentation] 腫瘍に高発現する酸化酵素ERO1-αは、腫瘍増殖環境を整える

    • Author(s)
      田中 努、田村 保明、梶原 敏充、鳥越 俊彦、岡本 芳晴、佐藤 昇志
    • Organizer
      第9回臨床ストレス応答学会
    • Place of Presentation
      岡山市
    • Year and Date
      2014-11-01 – 2014-11-02
    • Data Source
      KAKENHI-PROJECT-24590448
  • [Presentation] Heat shock protein 90 is involved in antibody-mediated rejection and is a potential target of anti-rejection therapy in kidney transplantation

    • Author(s)
      Toshiaki Tanaka, Hideki Ishida, Miyuki Furusawa, Yasuaki Tamura, Hiroshi Kitamura, Satoshi Takahashi, Naoya Masumori, Kazunari Tanabe, Noriyuki Sato and Taiji Tsukamoto
    • Organizer
      28st Annual European Urology Association Congress
    • Place of Presentation
      イタリア ミラノ
    • Data Source
      KAKENHI-PROJECT-24592448
  • [Presentation] 熱ショック蛋白質HSPによる自己免疫疾患制御

    • Author(s)
      田村保明
    • Organizer
      日本病理学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590427
  • [Presentation] Enhanced expression of endoplasmic reticulum disulfide oxidase 1-α (ERO1-α) inhibits anti-tumor immune response.

    • Author(s)
      田中 努、田村 保明、久木田 和晴、梶原 敏充、鳥越 俊彦、岡本 芳晴、佐藤 昇志
    • Organizer
      第72回日本癌学会
    • Place of Presentation
      横浜市
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24590448
  • 1.  SATO Noriyuki (50158937)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 62 results
  • 2.  TORIGOE Toshihiko (20301400)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 35 results
  • 3.  ICHIMIYA Shingo (30305221)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 4.  HIROHASHI Yoshihiko (30516901)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 29 results
  • 5.  SAHARA Hiroeki (10260762)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  KIKUCHI Tomoki (50404588)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  MATSUZAKI Junichi (80448597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  HIRATA Koichi (50136959)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 9.  MIZUGUCHI Toru (30347174)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  KIMURA Yasutoshi (80311893)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 11.  KUTOMI Goro (10404625)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 12.  OGAWA Tadashi (70516658)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KOUNO Tsuyoshi (50516664)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  YAMAZAKI Koichi (20312358)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 15.  TANI Kenzaburo (00183864)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 16.  AKITA Hirotoshi (70222528)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 17.  KAMIGUCHI Kenjiro (70363695)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  Saito Hiroya (80524769)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  田中 俊明 (50398327)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 20.  池田 英之 (40301494)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  水上 裕輔 (30400089)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  Nabeel Bardeesy
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  KOBAYASHI Junichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  SASAKI Takanori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  仲盛 健治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  宮崎 晃亘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  平塚 博義
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  VITALY Kochin
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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