MAKINO TOSHIAKI 牧野利明

… Alternative Names

MAKINO Toshiaki 牧野利明

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Researcher Number	80326561
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(薬学), 教授
Affiliation (based on the past Project Information) *help	2019 – 2025: 名古屋市立大学, 医薬学総合研究院(薬学), 教授 2016 – 2018: 名古屋市立大学, 大学院薬学研究科, 教授 2013 – 2015: 名古屋市立大学, 薬学研究科(研究院), 教授 2011 – 2012: 名古屋市立大学, 薬学研究科(研究院), 准教授 2007 – 2012: Nagoya City University, 大学院・薬学研究科, 准教授 2006: 名古屋市立大学, 大学院薬学研究科, 講師
Review Section/Research Field	Principal Investigator General internal medicine (including Psychosomatic medicine) / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Natural medicines / General internal medicine(including psychosomatic medicine) Except Principal Investigator Basic Section 52010:General internal medicine-related / General internal medicine(including psychosomatic medicine) / Basic Section 47050:Environmental and natural pharmaceutical resources-related / General internal medicine (including Psychosomatic medicine) / Medical pharmacy
Keywords	Principal Investigator 漢方薬 / 副作用 / 偽アルドステロン症 / トランスポーター / ブシ / 甘草 / 個体差 / 腸内細菌 / 代謝産物 / シャゼンシ … More / 附子 / 茯苓 / 沢瀉 / 車前子 / Sirtuin遺伝子1 / 牛車腎気丸 / サルソリノール / ヒゲナミン / ユビキチンリガーゼ / サルコペニア / アロディニア / 加工ブシ / オキサリプラチン / パクリタキセル / ネオリン / 神経障害性疼痛 / トリカブト / グリチルリチン / 遺伝子多型 / ヒドロキシステロイド脱水素酵素 / グリチルレチン酸 / ヒドロキンステロイド脱水素酵素 / グリチルリチン酸 / 有機アニオントランスポーター / 東洋医学 / Caco-2細胞 / 生薬 … More Except Principal Investigator 漢方薬 / 補中益気湯 / 修治 / 加熱 / 人参養栄湯 / 末梢神経障害 / オキサリプラチン / 大腸癌 / カラスビシャク / レクチン / 針状結晶 / 半夏 / 瀉下 / 血流改善 / 内皮型一酸化窒素合成酵素（eNOS） / トロンビン / 一酸化窒素（NO） / 大黄 / 副作用の予防 / 検査キット / マウス抗血清 / ELISA / モノクローナル抗体 / 硫酸抱合体 / 甘草 / 偽アルドステロン症 / 肺炎球菌 / 肺炎球菌ワクチン / 生薬 / 免疫賦活作用 / G-CSF / TLR4 / 高分子 / 加熱加工 / isomaltose / 蜜炙 / トール様受容体 / 腸管免疫 / 顆粒球コロニー刺激因子 / イソマルトース / 蜂蜜 / 臨床試験 / 神経毒性 / 血液毒性 / XELOX / 術後補助化学療法 / 医療用漢方製剤 / 細菌 / 感染症 / DNAアーゼ / 溶血毒素 / ＭＲＳＡ / mecA / MRSA / 抗がん剤 / 臨床 / 内科 / 癌 / 人参栄養湯 / 漢方 / connective tissue growth factor / 釣藤鈎 / Asymmetric dimethylarginine / 七物降下湯 / 慢性腎臓病(CKD) Less

Identification of intestinal bacteria that determine the usefulness and individual differences of human-specific glycyrrhizic acid metabolitesPrincipal Investigator
- Principal Investigator
  
  牧野利明
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Nagoya City University
生薬ハンゲによる咽喉刺激痛の発生および薬効の発現におけるレクチンの役割
- Principal Investigator
  
  笛木司
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Nagoya City University
バンコマイシン耐性腸球菌感染に対する補中益気湯による薬剤感受性回復治療の提案
- Principal Investigator
  
  南正明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Nagoya City University
大黄の修治による血流改善メカニズムの解明および漢方処方への応用
- Principal Investigator
  
  太田美里
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Nagoya City University
Development of analytical kit for causative agent to cause licorice-induced pseudoaldosteronism
- Principal Investigator
  
  森永紀
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
Development of goshajinkigan products for the prevention of sarcopeniaPrincipal Investigator
- Principal Investigator
  
  Toshiaki Makino
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Nagoya City University
Trial of combined use of Kampo medicine for pneumococcal vaccine therapy-Proposal of a new treatment aiming at enhancement of antibody titer
- Principal Investigator
  
  南正明
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Nagoya City University
Processing of crude drugs - The mechanism of the appearance of immunostimulatory activity by heating with honey
- Principal Investigator
  
  Ota Misato
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Nagoya City University
Effect of processed aconite root on neuropathic pain and its active ingredients and action mechanismsPrincipal Investigator
- Principal Investigator
  
  Makino Toshiaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Nagoya City University
ashgd
- Principal Investigator
  
  minami masaaki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Nagoya City University
Clinical effect and its molecular mechanism of ninjin'yoeito on the hemato-, and neuro-toxicities of oxaliplatin
- Principal Investigator
  
  MOTOO Yoshiharu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Kanazawa Medical University
Development of analytical kit to prevent licorice-induced pseudoaldsteronismPrincipal Investigator
- Principal Investigator
  
  Makino Toshiaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Nagoya City University
Developing mechanisms of pseudoaldosteronism by taking licorice and its preventive methodPrincipal Investigator
- Principal Investigator
  
  MAKINO Toshiaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Nagoya City University
Clinical efficacy and its molecular mechanisms of ninjinyoeito on oxaliplatin-induced peripheral neuropathy
- Principal Investigator
  
  MOTOO Yoshiharu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Kanazawa Medical University
Systemic vascular disorders in chronic kidney disease and screening for protective drugs
- Principal Investigator
  
  ONO Takahiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya City University
Relationship between the adverse effect of kampo medicine and transportersPrincipal Investigator
- Principal Investigator
  
  MAKINO Toshiaki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Nagoya City University
漢方薬・西洋薬間相互作用の消化管細胞培養システムを用いたスクリーニング法Principal Investigator
- Principal Investigator
  
  牧野利明
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Nagoya City University

[Book] いまさら聞けない生薬・漢方薬2015
- Author(s)
  牧野利明
- Total Pages
  195
- Publisher
  医薬経済社
- Data Source
  KAKENHI-PROJECT-25460907
[Book] Traditional Medicine – New Research2013
- Author(s)
  Toshiaki Makino, Nobuhiro Ohtake
- Total Pages
  274
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-25460907
[Book] Mechanisms of licorice-induced pseudoaldosteronism, one of the most common side effects of traditional Japanese kampo medicine and traditional Chinese medicine“Traditional Medicine – New Research” ed. Yoshiharu Motoo2013
- Author(s)
  Toshiaki Makino, Nobuhiro Ohtake
- Publisher
  Nova Science Publishers, New York
- Data Source
  KAKENHI-PROJECT-23790748
[Book] Mechanisms of licorice-induced pseudoaldosteronism, one of the most common side effects of traditional Japanese kampo medicine and traditional Chinese medicine2013
- Author(s)
  Toshiaki Makino, Nobuhiro Ohtake
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-23790748
[Journal Article] Suppressive effects of processed aconite root on dexamethasone-induced muscle ring finger protein-1 expression and its active ingredients2022
- Author(s)
  Kondo Taishi、Ishida Tomoaki、Ye Ke、Muraguchi Marin、Tanimura Yohei、Yoshida Masato、Ishiuchi Kan’ichiro、Abe Tomoki、Nikawa Takeshi、Hagihara Keisuke、Hayashi Hidetoshi、Makino Toshiaki
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: － Issue: 3 Pages: 594-604
- DOI
  10.1007/s11418-022-01606-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07149, KAKENHI-PROJECT-19H04054, KAKENHI-PROJECT-20K07052
[Journal Article] Honey isomaltose contributes to the induction of granulocyte-colony stimulating factor (G-CSF) secretion in the intestinal epithelial cells following honey heating2020
- Author(s)
  Xu Xin、Asai Koshi、Kato Daiki、Ishiuchi Kan’ichiro、Ding Kewen、Tabuchi Yoshiaki、Ota Misato、Makino Toshiaki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1
- DOI
  10.1038/s41598-020-71993-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07453
[Journal Article] Neoline is the active ingredient of processed aconite root against murine peripheral neuropathic pain model, and its pharmacokinetics in rats2019
- Author(s)
  Yohei Tanimura, Masato Yoshida, Kan'ichiro Ishiuchi, Masahiro Ohsawa, Toshiaki Makino
- Journal Title
  
  Journal of Ethnopharmacology
  
  Volume: 241 Pages: 111859-111859
- DOI
  10.1016/j.jep.2019.111859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08298
[Journal Article] The immunostimulatory effects and chemical characteristics of heated honey2019
- Author(s)
  Ota Misato、Ishiuchi Kan’ichiro、Xu Xin、Minami Masaaki、Nagachi Yasutaka、Yagi-Utsumi Maho、Tabuchi Yoshiaki、Cai Shao-Qing、Makino Toshiaki
- Journal Title
  
  Journal of Ethnopharmacology
  
  Volume: 228 Pages: 11-17
- DOI
  10.1016/j.jep.2018.09.019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07453
[Journal Article] Effect of Hochuekkito (Buzhongyiqitang) on Nasal Cavity Colonization of Methicillin-Resistant Staphylococcus aureus in Murine Model.2018
- Author(s)
  Minami M, Konishi T, Makino T.
- Journal Title
  
  Medicines (Basel).
  
  Volume: 5(3) Issue: 3 Pages: 83-83
- DOI
  10.3390/medicines5030083
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09251
[Journal Article] Effect of ninjin’yoeito and ginseng extracts on oxaliplatin-induced neuropathies in mice2017
- Author(s)
  Suzuki Toshiaki、Yamamoto Ayano、Ohsawa Masahiro、Motoo Yoshiharu、Mizukami Hajime、Makino Toshiaki
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 71 Issue: 4 Pages: 757
- DOI
  10.1007/s11418-017-1113-6
- NAID
  40021338028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09267, KAKENHI-PROJECT-15K13100
[Journal Article] Processed aconite root and its active ingredient neoline may alleviate oxaliplatin-induced peripheral neuropathic pain2016
- Author(s)
  Toshiaki Suzuki, Keisuke Miyamoto, Naomi Yokoyama, Mayuko Sugi, Akina Kagioka, Yuka Kitao, Takumi Adachi, Masahiro Ohsawa, Hajime Mizukami, Toshiaki Makino
- Journal Title
  
  J. Ethenopharmacol.
  
  Volume: 186 Pages: 44
- DOI
  10.1016/j.jep.2016.03.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08298
[Journal Article] 3-Monoglucuronyl Glycyrrhretinic Acid Is a Possible Marker Compound Related to Licorice-Induced Pseudoaldosteronism2014
- Author(s)
  Toshiaki Makino
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 6 Pages: 898-902
- DOI
  10.1248/bpb.b13-00997
- NAID
  130004147345
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460907
[Journal Article] 3-Monoglucuronyl-glycyrrhretinic acid is a substrate of organic anion transporters expressed in tubular epithelial cells and plays important roles in licorice-induced pseudoaldosteronism by inhibiting 11β-hydroxysteroid dehydrogenase 22012
- Author(s)
  Toshiaki Makino
- Journal Title
  
  The Journal of Pharmacology and Experimental Therapeutics
  
  Volume: 342 Issue: 2 Pages: 297-304
- DOI
  10.1124/jpet.111.190009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790748
[Journal Article] Anti-hypertensive effects of shichimotsukokato in 5/6 nephrectomized Wistar rats mediated by DDAH-ADMA-NO pathway2012
- Author(s)
  Fan Bai, Toshiaki Makino, Takahiko Ono, Hajime Mizukami
- Journal Title
  
  J.Nat.Med.
  
  Volume: (印刷中) Issue: 4 Pages: 583-590
- DOI
  10.1007/s11418-011-0625-8
- NAID
  10031088105
- Year and Date
  2012-02-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590172
[Journal Article] Roles of coagulation pathway and factor Xa in the progression of diabetic nephropathy in db/db mice2011
- Author(s)
  Ayaka Sumi, Natsuko Y Hanada, Fan Bai, Toshiaki Makino, Hajime Mizukami, Takahiko Ono
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 34(6) Pages: 824-830
- NAID
  130000738056
- Data Source
  KAKENHI-PROJECT-21590172
[Journal Article] Roles of coagulation pathway and factor Xa in the progression of diabetic nephropathy in db/db mice2011
- Author(s)
  Sumi A, Makino T, Ono T, et al.
- Journal Title
  
  Biol.Phar.Bull.
  
  Volume: (印刷中)
- NAID
  130000738056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590172
[Journal Article] 漢方薬の副作用～偽アルドステロン症のメカニズムとその発症予防策について2011
- Author(s)
  牧野利明、大嶽信弘
- Journal Title
  
  ファルマシア
  
  Volume: 47(5) Pages: 403-407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790748
[Journal Article] Basic study and clinical practice of Kampo medicines in chronic kidney disease(CKD) : chronic glomerulonephritis and nephrosclerosis2009
- Author(s)
  Takahiko Ono, Toshiaki Makino
- Journal Title
  
  J Trad Med 26
  
  Pages: 230-234
- NAID
  10025956286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590172
[Journal Article] Basic study and clinical practice of Kampo medicines in chronic kidney disease(CKD): chronic glomerulonephritis and nephrosclerosis2009
- Author(s)
  Takahiko Ono, Toshiaki Makino
- Journal Title
  
  J. Trad. Med.
  
  Volume: 26(5/6) Pages: 230-234
- NAID
  10025956286
- Data Source
  KAKENHI-PROJECT-21590172
[Journal Article] Down-regulation of a hepatic transporter Mrp2 is involved in alteration of pharmacokinetics of glycyrrhizin and its metabolites in a rat model of chronic liver injury.2008
- Author(s)
  Toshiaki Makino, Nobuhiro Ohtake, Akito Watanabe, Naoko Tsuchiya, Sachiko Imamura, Seiichi Iizuka, Makoto Inoue, Hajime Mizukami.
- Journal Title
  
  Drug Metab. Dispos. 36(7)
  
  Pages: 1438-1443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790475
[Journal Article] Down-regulation of a hepatic transporter multidrug resistance-associated protein 2 is involved in alteration of pharmacokinetics of glycyrrhizin and its metabolites in a rat model of chronic liver injury2008
- Author(s)
  Makino T, Ohtake N, Watanabe A, Tsuchiya N, Imamura S, Iizuka S, Inoue M, Mizukami H
- Journal Title
  
  Drug Metab Dispos 7
  
  Pages: 1438-1443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790475
[Journal Article] Shosaikoto (a Kampo medicine) modulates changes of cytochrome P450 caused by Mycobacterium butyricum injection2007
- Author(s)
  Nobukazu Ryu, Hiroki Tanabe, Toshiaki Makino, Hajime Mizukamti, Makoto Inou
- Journal Title
  
  J.Nat.Med 61
  
  Pages: 342-348
- NAID
  40015434583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790438
[Journal Article] Pharmacological characterization of a chronic pruritus model induced by multiple application of 2,4,6-trinitrochlorobenzene in NC mice2007
- Author(s)
  Hirotaka Yamashita, Toshiaki Makino, Hajime Mizukami, Mitsuhiko Nose
- Journal Title
  
  Eur.J.Pharmacol 563
  
  Pages: 233-239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790438
[Journal Article] Does a kampo medicine containing schisandra fruit affect pharmacokinetics of nifedipine like grapefruit juice?2006
- Author(s)
  Toshiaki Makino, Fumika Mizuno, Hajime Mizukami
- Journal Title
  
  Biol.Pharm.Bull. 29(10)
  
  Pages: 2065-2069
- NAID
  110004810293
- Data Source
  KAKENHI-PROJECT-18790438
[Journal Article] Anti-hypertensive effects of shichimotsukokato in 5/6 nephrectomized Wistar rats mediated by DDAH-ADMA-NO pathway
- Author(s)
  Fan Bai, Toshiaki Makino, Takahik o Ono, Hajime Mizukami
- Journal Title
  
  J. Nat. Med.
  
  Volume: (in press)
- NAID
  10031088105
- Data Source
  KAKENHI-PROJECT-21590172
[Patent] 免疫賦活活性組成物、免疫賦活活性剤、イソマルトース加熱産物の製造方法、及び経口摂取素材の免疫賦活活性評価方法2019
- Inventor(s)
  太田美里、牧野利明、許▲金▼、加藤大貴、田渕圭章
- Industrial Property Rights Holder
  太田美里、牧野利明、許▲金▼、加藤大貴、田渕圭章
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-229435
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K07453
[Presentation] G-CSF産生誘導活性を指標とした蜜炙法に適したハチミツの探索とその寄与成分2020
- Author(s)
  許キン、太田美里、加藤大貴、田渕圭章、牧野利明
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K07453
[Presentation] Paclitaxelによるマウス神経障害性疼痛に対する加工ブシの緩和作用2018
- Author(s)
  吉田理人、石内勘一郎、大澤匡弘、牧野利明
- Organizer
  第34回和漢医薬学会学術大会
- Data Source
  KAKENHI-PROJECT-16K08298
[Presentation] 加工ブシ成分、benzoylmesaconineとneolineの体内動態および神経障害性疼痛に対する作用の比較検討2018
- Author(s)
  谷村陽平、吉田理人、石内勘一郎、大澤匡弘、牧野利明
- Organizer
  第35回和漢医薬学会学術大会
- Data Source
  KAKENHI-PROJECT-16K08298
[Presentation] Inducible effect of heated honey on G-CSF secretion from cultured intestinal cells and its active ingredients2018
- Author(s)
  Xin Xu, Misato Ota, Yoshiaki Tabuchi, Shao-Qing Cai, Toshiaki Makino
- Organizer
  Nagoya Immunology Network in NCU
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07453
[Presentation] Mechanisms of honey-processing (蜜炙) in traditional Chinese nedicine: Its inducible effects on G-CSF secretion from cultured intestinal cells2018
- Author(s)
  Xin Xu, Misato Ota, Yoshiaki Tabuchi, Shao-Qing Cai, Toshiaki Makino
- Organizer
  The 19th International Congress of Oriental Medicine (台北)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07453
[Presentation] G-CSF産生誘導活性を指標とした蜜炙法に適したハチミツの探索2018
- Author(s)
  許金、太田美里、田渕圭章、牧野利明
- Organizer
  天然薬物研究方法論アカデミー第２１回研究集会（蒲郡シンポジウム）
- Data Source
  KAKENHI-PROJECT-18K07453
[Presentation] 補中益気湯によるMRSAの薬剤感受性回復と病原毒素抑制効果の検討2017
- Author(s)
  南正明, 牧野利明
- Organizer
  和漢医薬学会
- Data Source
  KAKENHI-PROJECT-16K09251
[Presentation] Processed aconite root (附子) and its active ingredient neoline may alleviate oxaliplatin-induced peripheral neuropathic pain2016
- Author(s)
  Toshiaki Suzuki, Keisuke Miyamoto, Naomi Yokoyama, Mayuko Sugi, Akina Kagioka, Takumi Adachi, Masahiro Ohsawa, Hajime Mizukami, Toshiaki Makino
- Organizer
  The 18th International Congress of Oriental Medicine
- Place of Presentation
  Okinawa
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08298
[Presentation] 甘草の副作用、偽アルドステロン症発症推定原因物質 3MGA の ELISA による定量法の開発2013
- Author(s)
  森永紀、牧野利明、大北剛司、水上元、正山征洋
- Organizer
  日本薬学会第133回年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-23790748
[Presentation] 漢方研究のターゲットとしてのトランスポーター2013
- Author(s)
  牧野利明
- Organizer
  日本薬物動態学会・トランスポーター研究会合同シンポジウム
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23790748
[Presentation] Effects of shichimotsukokato on hypertensive CKD model2011
- Author(s)
  白帆、牧野利明、小野孝彦、水上元
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山
- Year and Date
  2011-08-28
- Data Source
  KAKENHI-PROJECT-21590172
[Presentation] 甘草の副作用、偽アルドステロン症発症メカニズムに関する研究2011
- Author(s)
  岡島恭子、牧野利明、井上勝央、大嶽信弘、水上元
- Organizer
  日本生薬学会第58回年会
- Place of Presentation
  東京
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23790748
[Presentation] グリチルリチンおよびその代謝物の腎における11β-HSD II阻害作用の比較2010
- Author(s)
  上林理絵、牧野利明、井上勝央、水上元、大嶽信弘
- Organizer
  第130回日本薬学会年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20790475
[Presentation] グリチルリチンおよびその代謝物の腎における11 β-HSD II阻害作用の比較2009
- Author(s)
  上林理絵、牧野利明、井上勝央、水上元、大嶽信弘
- Organizer
  第130回日本薬学会年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20790475
[Presentation] シンポジウム慢性腎臓病(CKD)と漢方:慢性腎炎・腎硬化症への漢方方剤の運用と基礎的検討2009
- Author(s)
  小野孝彦, 牧野利明
- Organizer
  第26回和漢医薬学会
- Place of Presentation
  千葉市
- Year and Date
  2009-08-30
- Data Source
  KAKENHI-PROJECT-21590172

1. minami masaaki (70418739)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. MOTOO Yoshiharu (80210095)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Morinaga Osamu (60465771)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Ota Misato (00767121)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. 石内勘一郎 (70608140)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. ONO Takahiko (60243028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. SAIKI Ikuo (80133776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAKANO Fumihide (20236251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ISHIGAKI Yasuhito (20232275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SHIMASAKI Takeo (50377420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 大澤匡弘 (80369173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. 杉山大介 (00426652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 藤田秀人 (20401903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 小川鶴洋 (40781646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 大磯茂 (40513106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 笛木司 (10812050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 寺坂和祥 (60405214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 吉野鉄大 (50728615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. Tanimura Yohei

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. Yoshida Masato

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

MAKINO TOSHIAKI 牧野 利明

MAKINO Toshiaki 牧野 利明

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Identification of intestinal bacteria that determine the usefulness and individual differences of human-specific glycyrrhizic acid metabolitesPrincipal Investigator

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Development of goshajinkigan products for the prevention of sarcopeniaPrincipal Investigator

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Effect of processed aconite root on neuropathic pain and its active ingredients and action mechanismsPrincipal Investigator

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Development of analytical kit to prevent licorice-induced pseudoaldsteronismPrincipal Investigator

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Developing mechanisms of pseudoaldosteronism by taking licorice and its preventive methodPrincipal Investigator

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MAKINO TOSHIAKI 牧野利明

MAKINO Toshiaki 牧野利明