HISASUE Masaharu 久末正晴

Researcher Number	80333144
Other IDs
External Links
Affiliation (Current)	2019: 麻布大学, 獣医学部, 准教授
Affiliation (based on the past Project Information) *help	2008 – 2018: 麻布大学, 獣医学部, 准教授 2007: 麻布大学, 獣医学部, 講師 2006: 麻布大, 獣医学部, 講師 2004 – 2005: Azabu University, School of Veterinary Medicine, Instructor, 獣医学部, 講師 2001 – 2003: Azabu University, Faculty of Veterinary Medicine, assistant, 獣医学部, 助手
Review Section/Research Field	Principal Investigator Veterinary medical science / Clinical veterinary science / Applied veterinary science Except Principal Investigator Clinical veterinary science / Applied veterinary science / Veterinary medical science / Integrative animal science / Hematology
Keywords	Principal Investigator 骨髄 / 皮膚 / 犬 / 分化誘導 / 肝臓 / 幹細胞 / 再生 / 肝細胞増殖因子 / 分化 / CD45f … More Except Principal Investigator イヌ / c-Met / MDM2 / 獣医学 / ネコ / HGF / 再生医療 / vitamin D3 / 骨髄細胞 / センダイウイルスベクター / 犬 / differentiation / 症例 / 抗ウイルス活性 / 伴侶動物 / 内在性レトロウイルス / ウイルス / apoptosis / ウイルス進化 / 肝細胞 / bone marrow / 腫瘍マーカー / テロメア / P-glycoprotein / 家猫 / canine / 乳腺腫瘍 / 細胞周期 / P糖蛋白質 / p21CIP1 / 共進化 / アトピー性皮膚炎 / Cry j 1 / 幹細胞 / 胎盤抽出物 / placental extract / マウス乳癌ウイルス / Telomerase / 骨髄異形成症候群 / ゲノム / MMTV / 進化 / regenerative medicine / 獣医再生医療 / ネコ科動物 / Telomere / Feline leukemia virus / アポトーシス / hepatocyte / DNAワクチン / 発現制御 / FcERV-gamma4 / 肝臓 / iPS細胞 / 感染 / ビタミンK2 / T細胞エピトープ / テロメラーゼ / Clonarity / p53 / 家畜化 / 血液 / 多能性幹細胞 / vitamin K2 / 分化 / Tumor marker / 急性白血病 / P糖蛋白 / ビタミンD3 / C-Met / 再生獣医療 / 猫 / 薬剤耐性 / myelodysplastic syndrome / 猫白血病ウイルス / Multidrug resistance / Refrex-1 / P53 / レトロウイルス / 猫白血病ウイルス(FeLV) / leukemia / cell cycle / クローナリティー / 白血病 / FeLV / ERV-DC / 遺伝学 Less

イヌの皮膚線維芽細胞から肝細胞への直接分化誘導法の確立Principal InvestigatorOngoing
- Principal Investigator
  
  久末正晴
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Veterinary medical science
- Research Institution
  Azabu University
レトロウイルスの家畜化と宿主機能遺伝子への変化Ongoing
- Principal Investigator
  
  西垣一男
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Integrative animal science
- Research Institution
  Yamaguchi University
Investigation of erythroid differentiation using transgene-free canine and feline induced pluripotent stem cells
- Principal Investigator
  
  Hatoya Shingo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Osaka Prefecture University
Differentiation of hematopoietic cell from Cutaneous fibroblasts by direct reprogramingPrincipal Investigator
- Principal Investigator
  
  Hisasue Masaharu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Veterinary medical science
- Research Institution
  Azabu University
Establishment of liver regenerative medicine by autologous transplantation in dogPrincipal Investigator
- Principal Investigator
  
  HISASUE Masaharu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Azabu University
乳腺腫瘍の犬や猫にマウス乳癌ウイルス(MMTV)は感染しているか?
- Principal Investigator
  
  Tsuchiya Ryo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Clinical veterinary science
- Research Institution
  Azabu University
イヌの骨髄細胞から分化した肝臓細胞の性状および機能解析に関する研究Principal Investigator
- Principal Investigator
  
  久末正晴
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Azabu University
Studies on regenerative medicine by using bone marrow stem cell in intractable hepatic diseases
- Principal Investigator
  
  YAMADA Takatsugu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Azabu University
ネコの血液腫瘍におけるビタミンK2による分化誘導療法の検討Principal Investigator
- Principal Investigator
  
  久末正晴
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  Azabu University
Establishment of Vitamin K2 Therapy in Myelodysplastic Syndromes
- Principal Investigator
  
  MIYAZAWA Keisuke
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Medical University
Usefulness of tumor markers in veterinary medicine
- Principal Investigator
  
  TSUJIMOTO Hajime
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  THE UNIVERSITY OF TOKYO

All 2017 2013 2012 2011 2005 2004 2003

All Journal Article Presentation

[Journal Article] AKT capture by feline leukemia virus2017
- Author(s)
  Kawamura M, Umehara D, Odahara Y, Miyake A, Ngo MH, Ohsato Y, Hisasue M, Nakaya MA, Watanabe S, Nishigaki K.
- Journal Title
  
  Archives of Virology
  
  Volume: 162(4) Pages: 1031-1036
- DOI
  10.1007/s00705-016-3192-1
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04602, KAKENHI-PROJECT-15K08138
[Journal Article] Accumulation of Xenotransplanted Canine Bone Marrow Cells in NOD/SCID/γcnull Mice with Acute Hepatitis Induced by CCl42013
- Author(s)
 Kato T, Hisasue M, Segawa K, Fujimoto A, Makiishi E, Neo S, Yasuno K, Kobayashi R, Tsuchiya R.
- Journal Title
 
 J. Vet. Med. Sci.
 
 Volume: 75 Issue: 7 Pages: 847-855
- DOI
 10.1292/jvms.12-0530
- ISSN
 0916-7250, 1347-7439
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-22580371
[Journal Article] Accumulation of xenotransplanted canine bone marrow cells in NOD/SCID/γcnull mice with hepatitis induced by CCl42013
- Author(s)
  Takashi Kato, Masaharu Hisasue, Kazuhito Segawa, Ayumi Fujimoto, Eri Makiishi, Sakurako Neo, Kyohei Yasuno, Ryosuke Kobayashi and Ryo Tsuchiya
- Journal Title
  
  J. Vet. Med. Sci
  
  Volume: 75(7) Pages: 845-855
- Data Source
  KAKENHI-PROJECT-22580371
[Journal Article] 犬のBabesia gibson自然症例におけるPCR法及びELISA法による診断の比較2005
- Author(s)
  渡辺征, 久末正晴, 相馬武久他
- Journal Title
  
  日獣会誌 58
  
  Pages: 622-626
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15580294
[Journal Article] Comparative investigation of canine Babesia gibsoni infction using polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA).2005
- Author(s)
  Watanabe, T., Hisasue, M., Souma, T.et al.
- Journal Title
  
  J. Jpn. Vet. Med. Assoc. 58
  
  Pages: 622-626
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580294
[Journal Article] In vitro selective suppression of feline myeloid colony formation is attributable to molecularly cloned strain of feline leukemia virus with unique long terminal repeat2005
- Author(s)
  Nagashima N, Hisasue M, et al.
- Journal Title
  
  Res Vet Sci 78
  
  Pages: 151-154
- Data Source
  KAKENHI-PROJECT-17780240
[Journal Article] Molecular Cloning of the canine c-Met/HGF receptor and its expression in normal and regenerated liver2005
- Author(s)
  Neo S, Kansaku N, Furuich M, Watanabe M, Hisamatsu S, Ohno K, Hisasue M, Tsuchiya R, Yamada T
- Journal Title
  
  J.Vet.Med.Sci (In press)
- Data Source
  KAKENHI-PROJECT-15580294
[Journal Article] In vitro selective suppression of feline myeloid colony formation by a molecularly cloned strain of feline leukemia virus with unique long terminal repeat2005
- Author(s)
  Nagashima N, Hisasue M, Nishigaki K, Miyazawa Y, Kano R, Hasegawa
- Journal Title
  
  Res in Vet Sci (in press)
- Data Source
  KAKENHI-PROJECT-15580294
[Journal Article] Treatment of chronic lymphocytic leukaemia in three dogs with melphalan and prednisolone2004
- Author(s)
  Fujino, Y, Sawamura, S, Kurakawa, N, Hisasue, M, Masuda, K, Ohno, K, Tsujimoto, H
- Journal Title
  
  J Small Anim Pract 45
  
  Pages: 298-303
- Data Source
  KAKENHI-PROJECT-15580294
[Journal Article] Molecular detection and characterization of Haemobartonella fe lis in domestic cats in Japan employing sequence-specific polymerase chain reaction(SS-PCR)2003
- Author(s)
  Watanabe M., Hisasue M., Hashizaki K.et al.
- Journal Title
  
  J. Vet. Med. Sci. 65
  
  Pages: 1111-1114
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580294
[Journal Article] Aggregability and post-transfusion survival of canine platelets in stored whole blood2003
- Author(s)
  Tsuchiya R, Yagura H, Hachiya Y, Mochizuki T, Furuichi M, Hisasue M, Kobayashi K, Yamada T
- Journal Title
  
  J.Vet.Med.Sci 65
  
  Pages: 825-829
- Data Source
  KAKENHI-PROJECT-15580294
[Journal Article] Molecular detection and characterization of haemobartomella felis in domestic cats in Japan employing sequence-specific polymerase c hain reaction(SS-PCR)2003
- Author(s)
  Watanabe M., Hisasue M., Hashizaki K., et al.
- Journal Title
  
  J. Vet. Med. Sci. 65
  
  Pages: 1111-1114
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15580294
[Presentation]2013
- Author(s)
  加藤崇、久末正晴、瀬川和仁、藤本あゆみ、安野恭平、小林亮介、根尾櫻子、土屋亮
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22580371
[Presentation] NOGマウスを利用したイヌ骨髄細胞の障害肝へのHoming作用の解析2012
- Author(s)
  加藤崇、久末正晴、瀬川和仁、藤本あゆみ、根尾櫻子、小林亮介、土屋亮
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-22580371
[Presentation] 四塩化炭素急性肝障害NOGマウスに対するイヌ骨髄細胞投与の検討2012
- Author(s)
  加藤崇、久末正晴、瀬川和仁、藤本あゆみ、安野恭平、小林亮介、根尾櫻子、土屋亮
- Organizer
  第19回肝細胞研究会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22580371
[Presentation] 犬の骨髄細胞からの肝細胞の分化誘導2011
- Author(s)
  久末正晴
- Organizer
  獣医内科学アカデミー
- Place of Presentation
  横浜
- Year and Date
  2011-03-12
- Data Source
  KAKENHI-PROJECT-22580371
[Presentation] NOD/shi-scid,IL-2γnull(NOG)マウスにおける肝障害モデル作製に関する研究2011
- Author(s)
  加藤崇、久末正晴、根尾櫻子、藤本あゆみ、土屋亮
- Organizer
  第152回日本獣医学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22580371

1. HATOYA Shingo (40453138)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. Tsuchiya Ryo (30188586)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. MDARAME Hiroo (20173768)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. OGIHARA Kikumi (50154381)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. YAMADA Takatsugu (20126460)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. TSUJIMOTO Hajime (60163804)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. NEO Sakurako (50532107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. SASAKI Nobuo (60107414)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MASUDA Kenichi (40313077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OHNO Koichi (90294660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OKUDA Masaru (10325243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MIYAZAWA Keisuke (50209897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. IKEBUCHI Keinji (20175194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAKANISHI Mahito (10172355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 阪口雅弘 (20170590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 西垣一男 (20401333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 三宅在子 (20548622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 杉浦喜久弥 (30171143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 竹中重雄 (10280067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NAKAMURA Takuro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 白石明郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. NAKAYA Masaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HISASUE Masaharu 久末 正晴

Research Projects

Research Products

Co-Researchers

イヌの皮膚線維芽細胞から肝細胞への直接分化誘導法の確立Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

レトロウイルスの家畜化と宿主機能遺伝子への変化Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of erythroid differentiation using transgene-free canine and feline induced pluripotent stem cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Differentiation of hematopoietic cell from Cutaneous fibroblasts by direct reprogramingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of liver regenerative medicine by autologous transplantation in dogPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

乳腺腫瘍の犬や猫にマウス乳癌ウイルス(MMTV)は感染しているか?

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

イヌの骨髄細胞から分化した肝臓細胞の性状および機能解析に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on regenerative medicine by using bone marrow stem cell in intractable hepatic diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ネコの血液腫瘍におけるビタミンK2による分化誘導療法の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of Vitamin K2 Therapy in Myelodysplastic Syndromes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Usefulness of tumor markers in veterinary medicine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] AKT capture by feline leukemia virus2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Accumulation of Xenotransplanted Canine Bone Marrow Cells in NOD/SCID/&gamma;<sub>c</sub><sup>null</sup> Mice with Acute Hepatitis Induced by CCl<sub>4</sub>2013

Author(s)

Journal Title

DOI

ISSN

HISASUE Masaharu 久末正晴

[Journal Article] Accumulation of Xenotransplanted Canine Bone Marrow Cells in NOD/SCID/γ<sub>c</sub><sup>null</sup> Mice with Acute Hepatitis Induced by CCl<sub>4</sub>2013