yoshioka kazuaki 吉岡和晃

… Alternative Names

YOSHIOKA Kazuaki 吉岡和晃

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Researcher Number	80333368
Other IDs	https://orcid.org/0000-0002-8631-3846
External Links
Affiliation (Current)	2025: 金沢大学, 医学系, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 金沢大学, 医学系, 准教授 2017 – 2021: 金沢大学, 医学系, 講師 2008 – 2016: Kanazawa University, 医学系, 助教 2009: 金沢大学, 医学系, 助手 2007: 金沢大学, 医学系研究科, 助教 2002 – 2006: Kanazawa University, School of Medicine, Research Associate, 医学系研究科, 助手
Review Section/Research Field	Principal Investigator General physiology / Basic Section 48020:Physiology-related Except Principal Investigator General physiology / Biological Sciences / Basic Section 55030:Cardiovascular surgery-related / Basic Section 59040:Nutrition science and health science-related / Pathological medical chemistry / Basic Section 56020:Orthopedics-related / General physiology
Keywords	Principal Investigator ノックアウトマウス / PI3キナーゼ / 細胞内小胞輸送 / 血管内皮細胞 / イノシトールリン脂質 / 解離性大動脈瘤 / 血管透過性 / 血管新生 / 肺線維化 / 肺胞 … More / ミオチュブラリン / ホスファチジルイノシトール / リソソーム / オートファジー / ミオチュブラリン関連タンパク質 / 脂質ホスファターゼ / ホスホイノシタイド / エンドソーム / 低分子量Gタンパク質 / 血管恒常性 / Vasa Vasorum / 大動脈瘤 / 大動脈解離 / 肺胞上皮細胞 / ミオチューブラリン関連タンパク質 / 2型肺胞上皮細胞 / 肺胞幹細胞 / 肺線維症 / Ⅱ型肺胞上皮細胞 / エンドリソソーム / イノシトールリン脂質代謝酵素 / 細胞内膜輸送 / 肺上皮細胞 / クラスII型PI3キナーゼ / MTMR4 / ホスホイノシチド / 細胞内クリアランス / II型肺胞上皮細胞 / エンドサイトーシス / PI(3)P ホスファターゼ / 粥状動脈硬化 / PI(3)Pホスファターゼ / 動脈硬化 / 血管炎症 / KOマウス / ホスフォイノシチド / ノックアウトノックアウト / VEカドヘリン / 低分子量Gタンパク質Rho / 蛍光ライブイメージング / VE-カドヘリン / 内皮細胞 / 細胞膜輸送 / モデル動物 / 血管障害 / カルシウム感受性調節 / Rhoキナーゼ / 伸展力 / シグナル伝達 / カルシウム / ミオシン・フォスファターゼ / Rho / 収縮 / 血管平滑筋 … More Except Principal Investigator Rac / Rho / スフィンゴシン-1-リン酸 / Edg / 細胞運動 / イノシトールリン脂質 / PI3キナーゼ / 遊走 / 転移 / 浸潤 / スフィンゴシン１－リン酸 / 褐色脂肪細胞 / リソソーム / スフィンゴシンキナーゼ / cell motility / sphingosine-1-phosphate / AGR-16 / EDG / PI3-キナーゼ / 脂質 / ノックアウトマウス / 血管新生 / がん / Edg受容体 / S1P / 細胞外小胞 / 変形性膝関節症 / フィルムモデル法 / ゲル状分泌組織 / バイオマーカー / 胸腹部大動脈瘤 / 脊髄虚血 / 一酸化窒素 / 血管内皮 / 冠動脈バイパス術 / 肥満 / トリグリセリド / スフィンゴシン1-リン酸 / トランスジェニック / マウス / ノックアウト / gene targeting / Cell migration / Receptor / Sphingosme-1-phosphate / トランスジェニックマウス / 情報伝達 / 形態形成 / 器官形成 / EDG受容体 / 細胞遊走 / 受容体 / フォスファターゼ / 内皮 / 血管 / 小胞 / ホスファターゼ / ホスホイノシチド / 循環器疾患 / 生理学 / 生体分子 / 循環器・高血圧 / 血管医学 / 血管障壁 / シグナル伝達 / スフィンゴシンー１－リン酸 / 脂質メディエーター / イノシトールリン酸 / 血管障害 / アナフィラキシー / 動脈瘤 / 血管透過性 / 血管障壁機能 / 血管恒常性 / 小胞輸送 / PI 3-キナーゼ / 分子病態学 / 病態生理 / ホメオスターシス / 心血管 / SIP / SIP_2 / 血管成熟 / S1P_2 / フィンゴシン-1-リン酸 / G蛋白共役型受容体 / 癌 Less

Here is the English translation of the title: Functional Structure of the Adventitial Vasa Vasorum in the Aorta and the Elucidation of the Pathogenic Mechanism of Diseases Caused by Its DisruptionPrincipal Investigator
- Principal Investigator
  
  吉岡和晃
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Kanazawa University
変形性膝関節症に対する新規結合組織修復薬の開発
- Principal Investigator
  
  中瀬順介
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kanazawa University
スフィンゴシン1-リン酸が制御するリソソームを介した熱産生機構の解明とその応用
- Principal Investigator
  
  盛重純一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kanazawa University
大血管手術後の脊髄虚血に関するバイオマーカーの測定と探索
- Principal Investigator
  
  竹村博文
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Kanazawa University
大伏在静脈周囲組織がグラフト血管内皮機能に与える影響に関する研究
- Principal Investigator
  
  飯野賢治
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Kanazawa University
Regulation of lung stem cells through intracellular clearance by lipid phosphatasePrincipal Investigator
- Principal Investigator
  
  Yoshioka Kazuaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Kanazawa University
Elucidation of thermogenic mechanism through sphingosine 1-phosphate production and its application to obesity treatment
- Principal Investigator
  
  Morishige Jun-ichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kanazawa University
Physiological roles of Phosphoinositide-specific phosphatase in lung development and maturation through regulating membrane trafficking.Principal Investigator
- Principal Investigator
  
  Yoshioka Kazuaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
Regulation of membrane trafficking through PI(3)P-metabolizing enzymes in endothelial cells.Principal Investigator
- Principal Investigator
  
  Yoshioka Kazuaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
Control of vascular barrier integrity by MTM family of phosphatidylinositol 3-phosphate phosphatase
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
Mechanisms for the regulation of vascular homeostasis by functional lipid molecules
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
Class II PI3 kinase C2alpha has an essential role in angiogenesis and vascular homeostasis through regulating endosomal traffickingPrincipal Investigator
- Principal Investigator
  
  YOSHIOKA Kazuaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
Disruption of vascular integrity by deficiency of PI3K class II αisoform in mice
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
Role of functionallipids in cardiovascular homeostasis and diseases
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
Mechanistic analysis of blood vessel formation in class II PI3 kinase C2・ knockout mousePrincipal Investigator
- Principal Investigator
  
  YOSHIOKA Kazuaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
Signaling for regulating hematogenous metastasis of tumors
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Interrated research on the physiological role ofbioactive sphingosine-1-phosphate and Edg receptors by using genetically engineered maice.
- Principal Investigator
  
  TAKUWA Yho
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
G蛋白共役型受容体による癌の浸潤・転移の制御とその分子メカニズム
- Principal Investigator
  
  多久和陽
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
伸展力を介した血管平滑筋トーヌスのカルシウム感受性制御Principal Investigator
- Principal Investigator
  
  吉岡和晃
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
G蛋白共役型受容体による癌の浸潤・転移の制御とその分子メカニズム
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Molecular dissection of the physiological role of bioactive sphingosine-1-phosphate and Edg receptors
- Principal Investigator
  
  TAKUWA Yho
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
Molecular biological analysis of the lipid morphogen sphingosine-1-phosphate
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University

[Book] S-1-P Signaling Methods and Protocols (Sphingosine-1-phosphate regulation of macrophages in atherosclerosis)(edited by Pebay A and Turksen K.)2011
- Author(s)
  Wang F, Okamoto Y, Yoshioka K, Takuwa Y.
- Publisher
  Springer, New York, NY, U.S.A.(in press)
- Data Source
  KAKENHI-PROJECT-20590207
[Book] Role of sphingosine-1-phosphate signaling in atherosclerosis, Lysophospholipid Receptors : Signaling and Biochemistry (Edited by Chun J, HIa T, Spiegel S, Moolenaar W)2011
- Author(s)
  Takuwa Y, Wang F, Okamoto Y, Yoshioka K, Takuwa N
- Publisher
  John Wiley & Sons, Hoboken, New Jersey, U.S.A(In press)
- Data Source
  KAKENHI-PROJECT-20590207
[Book] Lysophospholipid Receptors : Signaling and Biochemistry(Role of sphingosine-1-phosphate signaling in atherosclerosis)(Edited by Chun J, Hla T, Spiegel S、Moolenaar W)2011
- Author(s)
  Takuwa Y, Wang F, Okamoto Y, Yoshioka K, Takuwa N.
- Publisher
  John Wiley & Sons, Hoboken, New Jersey, U.S.A.(in press)
- Data Source
  KAKENHI-PROJECT-20590207
[Book] Sphingosine-1-phosphate regulation of macrophages in atherosclerosis" in S-1-P Signaling Methods and Protocols edited by Pebay A and Turksen K2011
- Author(s)
  Wang F, Okamoto Y, Yoshioka K, Takuwa Y
- Publisher
  Springer, New York, NY, U.S.A(In press)
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] Sphingosine kinase 1 is involved in triglyceride breakdown by maintaining lysosomal integrity in brown adipocytes2023
- Author(s)
  Morishige Jun-ichi、Yoshioka Kazuaki、Nakata Hiroki、Ishimaru Kazuhiro、Nagata Naoto、Tanaka Tamotsu、Takuwa Yoh、Ando Hitoshi
- Journal Title
  
  Journal of Lipid Research
  
  Volume: 64 Issue: 11 Pages: 100450-100450
- DOI
  10.1016/j.jlr.2023.100450
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K10866
[Journal Article] Differences in collagen types in the semitendinosus, quadriceps, and patellar tendons: A report using samples from an 11-year-old patient2023
- Author(s)
  Yushin Mizuno, Junsuke Nakase, Kazuaki Yoshioka, Takuya Sengoku, Rikuto Yoshimizu, Tomoyuki Kanayama, Yusuke Yanatori, Hiroyuki Tsuchiya
- Journal Title
  
  Knee
  
  Volume: May 4 Pages: 339-346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07273
[Journal Article] Suppression of androgen receptor signaling induces prostate cancer migration via activation of the CCL20-CCR6 axi2023
- Author(s)
  Kano H, Izumi K, Hiratsuka K, Toriumi R, Nakagawa R, Aoyama S, Kamijima T, Shimada T, Naito R, Kadomoto S, Iwamoto H, Yaegashi H, Kawaguchi S, Nohara T, Shigehara K, Kadono Y, Saito Y, Nakagawa-Goto K, Yoshioka K, Nakata H, Lin W-J, Mizokami A.
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 4 Pages: 1479-1490
- DOI
  10.1111/cas.15683
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07273
[Journal Article] Adipose-derived stem cell sheets promote meniscus regeneration regardless of whether the defect involves the inner half or the whole width of the anterior half of the medial meniscus in a rabbit model.2022
- Author(s)
  Asai K., Nakase J, Yoshioka K, Yoshimizu R, Kimura M, Tsuchiya H.
- Journal Title
  
  Arthroscopy.
  
  Volume: in press Issue: 9 Pages: 2672-2683
- DOI
  10.1016/j.arthro.2022.02.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07273
[Journal Article] Class II phosphatidylinositol 3-kinase-C2α is essential for Notch signaling by regulating the endocytosis of γ-secretase in endothelial cells2021
- Author(s)
  Shimizu Shota、Yoshioka Kazuaki、Aki Sho、Takuwa Yoh
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 5199-5199
- DOI
  10.1038/s41598-021-84548-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07273, KAKENHI-PROJECT-20K07260
[Journal Article] Class II phosphatidylinositol 3-kinase α and β isoforms are required for vascular smooth muscle Rho activation, contraction and blood pressure regulation in mice2020
- Author(s)
  Islam Shahidul、Yoshioka Kazuaki、Aki Sho、Ishimaru Kazuhiro、Yamada Hiroki、Takuwa Noriko、Takuwa Yoh
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 70 Issue: 1 Pages: 18-18
- DOI
  10.1186/s12576-020-00745-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07864, KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-17K08542, KAKENHI-PROJECT-18K15010, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-20K07273
[Journal Article] Everolimus-Eluting Biodegradable Abluminal Coating Stent versus Durable Conformal Coating Stent: Termination of the Inflammatory Response Associated with Neointimal Healing in a Porcine Coronary Model2020
- Author(s)
  Mori Masayuki、Sakata Kenji、Yokawa Junichiro、Nakanishi Chiaki、Murai Kota、Okada Hirofumi、Shimojima Masaya、Yoshida Shohei、Yoshioka Kazuaki、Takuwa Yoh、Hayashi Kenshi、Yamagishi Masakazu、Kawashiri Masa-aki
- Journal Title
  
  Journal of Interventional Cardiology
  
  Volume: 2020 Pages: 1-8
- DOI
  10.1155/2020/1956015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07273
[Journal Article] TGFβ receptor endocytosis and Smad signaling require synaptojanin1?, PI3K-C2α?, and INPP4B?mediated phosphoinositide conversions2020
- Author(s)
  Aki Sho、Yoshioka Kazuaki、Takuwa Noriko、Takuwa Yoh
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 31(5) Issue: 5 Pages: 360-372
- DOI
  10.1091/mbc.e19-11-0662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-17K08542, KAKENHI-PROJECT-18K15010, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-20K07273
[Journal Article] Lysophosphatidic acid?induced YAP/TAZ activation promotes developmental angiogenesis by repressing Notch ligand Dll42019
- Author(s)
  Yasuda Daisuke、Kobayashi Daiki、Akahoshi Noriyuki、Ohto-Nakanishi Takayo、Yoshioka Kazuaki、Takuwa Yoh、Mizuno Seiya、Takahashi Satoru、Ishii Satoshi
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 129 Issue: 10 Pages: 4332-4349
- DOI
  10.1172/jci121955
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07472, KAKENHI-PROJECT-19H03411, KAKENHI-PROJECT-17K08532
[Journal Article] Class II PI3Ks α nad β are required for Rho-dependent uterine smooth muscle contraction and parturition in mice.2019
- Author(s)
  Sarker AK, Aki S, Yoshioka K, Kuno K, Okamoto Y, Ishimaru K, Takuwa N, and Takuwa Y.
- Journal Title
  
  Endocrinology
  
  Volume: 160 Issue: 1 Pages: 235-248
- DOI
  10.1210/en.2018-00756
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-17K08542, KAKENHI-PROJECT-18K15010, KAKENHI-PROJECT-16K15409
[Journal Article] The class II phosphoinositide 3-kinases PI3K-C2α and PI3K-C2β differentially regulate clathrin-dependent pinocytosis in human vascular endothelial cells.2019
- Author(s)
  Aung KT, Yoshioka K, Ishimaru K, Aki S, Takuwa N, and Takuwa Y.
- Journal Title
  
  Journal of Physiological Sciences
  
  Volume: 69 Issue: 2 Pages: 263-280
- DOI
  10.1007/s12576-018-0644-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-18K15010, KAKENHI-PROJECT-16K15409, KAKENHI-PROJECT-17K08542
[Journal Article] Sphigosine-1-phosphate receptor 1 promotes neointimal hyperplasia in a mouse model of carotid artery injury.2019
- Author(s)
  Kitano T, Takashima S, Inoue O, Goten C, Nomura A, Yoshioka K, Okajima M, Kaneko S, Takuwa Y, Takamura M.
- Journal Title
  
  Biochem. Biphys. Res. Communi.
  
  Volume: 511 Issue: 1 Pages: 179-184
- DOI
  10.1016/j.bbrc.2019.02.047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-16K09425
[Journal Article] MTMR4, a phosphoinositide specific 3’-phosphatase, regulates TFEB activity and the endocytic and autophagic pathways.2018
- Author(s)
  Pham HQ, Yoshioka K, Mohri H, Nakata H, Aki S, Ishimaru K, Takuwa N, and Takuwa Y.
- Journal Title
  
  Genes to Cells
  
  Volume: 23 Issue: 8 Pages: 670-687
- DOI
  10.1111/gtc.12609
- NAID
  120006621947
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-17K08542, KAKENHI-PROJECT-18K15010, KAKENHI-PROJECT-16K15409
[Journal Article] Photoacoustic imaging of tumor vascular permeability with indocyanine green in a mouse model.2018
- Author(s)
  Okumura K, Yoshida K, Yoshioka K, Aki S, Yoneda N, Inoue D, Kitao A, Ogi T, Kozaka K, Minami T, Koda W, Kobayashi S, Takuwa Y and Gabata T
- Journal Title
  
  European Radiology Experimental
  
  Volume: 2: 5 Issue: 1 Pages: 1-9
- DOI
  10.1186/s41747-018-0036-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-15H04673, KAKENHI-PROJECT-16K10343, KAKENHI-PROJECT-16K19812
[Journal Article] Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling.2017
- Author(s)
  Serafimidis I, Rodriguez-Aznar E, Lesche M, Yoshioka K, Takuwa Y, Dahl A, Pan D and Gavalas A.
- Journal Title
  
  PLOS Biology
  
  Volume: 15 (3) Issue: 3 Pages: e2000949-e2000949
- DOI
  10.1371/journal.pbio.2000949
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-15H04673, KAKENHI-PROJECT-26460292
[Journal Article] Early endothelialization associated with a biolimus A9 bioresorbable polymer stent in a porcine coronary model.2017
- Author(s)
  Mori M, Sakata K, Nakanishi C, Nakahashi T, Kawashiri MA, Yoshioka K, Takuwa Y, Okada H, Yokawa JI, Shimojima M, Yoshimuta T, Yoshida S, Yamagishi M, Hayashi K.
- Journal Title
  
  Heart Vessels.
  
  Volume: 32 Issue: 10 Pages: 1244-1252
- DOI
  10.1007/s00380-017-0992-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09118, KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-15H04673
[Journal Article] Augmented sphingosine 1 phosphate receptor-1 signaling in cardiac fibroblasts induces cardiac hypertrophy and fibrosis through angiotensin II and interleukin-6.2017
- Author(s)
  Ohkura SI, Usui S, Takashima SI, Takuwa N, Yoshioka K, Okamoto Y, Inagaki Y, Sugimoto N, Kitano T, Takamura M, Wada T, Kaneko S, Takuwa Y.
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 8 Pages: e0182329-e0182329
- DOI
  10.1371/journal.pone.0182329
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09425, KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-17K08542, KAKENHI-PROJECT-15H04673, KAKENHI-PROJECT-15K09135, KAKENHI-PROJECT-15K10970, KAKENHI-PROJECT-17H04166
[Journal Article] Phosphatidylinositol 3-kinase Class II α-Isoform PI3K-C2α Is Required for Transforming Growth Factor β-induced Smad Signaling in Endothelial Cells.2015
- Author(s)
  Aki S, Yoshioka K, Okamoto Y, Takuwa N, Takuwa Y.
- Journal Title
  
  J Biol Chem.
  
  Volume: 290 Issue: 10 Pages: 6086-6105
- DOI
  10.1074/jbc.m114.601484
- NAID
  120005593954
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390051, KAKENHI-PUBLICLY-25116711, KAKENHI-PROJECT-25670162, KAKENHI-PROJECT-26460292, KAKENHI-PROJECT-26460374, KAKENHI-PROJECT-15K10970, KAKENHI-PROJECT-15H04673
[Journal Article] クラスIIα型PI3キナーゼの血管内皮細胞における新しい生理機能2013
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和　陽
- Journal Title
  
  生化学会誌（ミニレビュー）
  
  Volume: 85 Pages: 775-780
- NAID
  10031202189
- Data Source
  KAKENHI-PROJECT-23590257
[Journal Article] Sphingosine-1-phosphate signaling and cardiac fibrosis.2013
- Author(s)
  Takuwa N, Okamoto Y., Yoshioka K. et al.
- Journal Title
  
  Inflammation & Regeneration
  
  Volume: 33 Pages: 96-108
- NAID
  130004943837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590257
[Journal Article] Sphingosine-1-phosphate receptor-2 protects against anaphylactic shock through suppression of eNOS in mice.2013
- Author(s)
  Cui H, Okamoto Y, Yoshioka K, et al.
- Journal Title
  
  J. Allergy Clin. Immunol.
  
  Volume: 132 Issue: 5 Pages: 1205-1214
- DOI
  10.1016/j.jaci.2013.07.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590257, KAKENHI-PROJECT-23590344, KAKENHI-PROJECT-24390051, KAKENHI-PUBLICLY-25116711, KAKENHI-PROJECT-25670162
[Journal Article] Sphingosine-1-Phosphate Signaling and Cardiac Fibrosis.2013
- Author(s)
  Takuwa N, Okamoto Y, Yoshioka K, Takuwa Y.
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 33 Pages: 96-108
- NAID
  130004943837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390051
[Journal Article] クラスII型PI3キナーゼC2αによる血管内皮シグナリング調節機能の蛍光ライブイメージング解析2013
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和　陽
- Journal Title
  
  日本血栓止血学会誌「総説」
  
  Volume: 24 Pages: 560-568
- NAID
  130003393318
- Data Source
  KAKENHI-PROJECT-23590257
[Journal Article] クラスIIα型PI3キナーゼの血管内皮細胞における新しい生理機能2013
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和陽
- Journal Title
  
  生化学会誌ミニレビュー
  
  Volume: 85(9) Pages: 775-780
- NAID
  10031202189
- Data Source
  KAKENHI-PROJECT-23590257
[Journal Article] PI3キナーゼ・ファミリーの血管における生理機能：クラスIIα型PI３キナーゼC2αによる新たな血管恒常性維持機構2013
- Author(s)
  吉岡　和晃
- Journal Title
  
  血管
  
  Volume: 36 Pages: 1-9
- NAID
  10031177130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659170
[Journal Article] Essential role of class II PI3K-C2α in sphingosine-1-phosphate receptor-1 mediated signaling and migration in endothelial cells2013
- Author(s)
  Biswas K, Yoshioka K, Asanuma K, Okamoto Y, Takuwa N, Sasaki T, TakuwaY
- Journal Title
  
  J. Biol. Chem
  
  Volume: 288 Issue: 4 Pages: 2325-2339
- DOI
  10.1074/jbc.m112.409656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590284, KAKENHI-PROJECT-23590257, KAKENHI-PROJECT-23590344, KAKENHI-PROJECT-23659170, KAKENHI-PROJECT-24390051, KAKENHI-PUBLICLY-23116509
[Journal Article] PI3キナーゼ・ファミリーの血管における生理機能: クラスIIα型PI3キナーゼC2αによる新たな血管恒常性維持機構2013
- Author(s)
  吉岡和晃吉田耕太郎、多久和典子、岡本安雄、多久和　陽
- Journal Title
  
  血管「総説」
  
  Volume: 36 Pages: 53-61
- NAID
  10031177130
- Data Source
  KAKENHI-PROJECT-23590257
[Journal Article] Sphingosine-1-Phosphate Signaling and Cardiac Fibrosis.2013
- Author(s)
  Takuwa N, Okamoto Y, Yoshioka K, Takuwa Y.
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 33 Pages: 96-108
- NAID
  130004943837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670162
[Journal Article] 細胞内小胞輸送制御を介して血管新生を促進するクラスII型PI3キナーゼ2013
- Author(s)
  吉岡和晃, 吉田耕太郎, 多久和典子, 岡本安雄, 多久和陽
- Journal Title
  
  BIO Clinica
  
  Volume: 28(5) Pages: 22-28
- Data Source
  KAKENHI-PROJECT-23590257
[Journal Article] 細胞内小胞輸送制御を介して血管新生を促進するクラスII型PI3キナーゼ2013
- Author(s)
  吉岡和晃吉田耕太郎、多久和典子、岡本安雄、多久和　陽
- Journal Title
  
  BIO Clinica
  
  Volume: 28 Pages: 22-28
- Data Source
  KAKENHI-PROJECT-23590257
[Journal Article] Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases2013
- Author(s)
  Takuwa Y
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 183 Issue: 1 Pages: 185-192
- DOI
  10.1016/j.bbalip.2012.06.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590284, KAKENHI-PROJECT-22590716, KAKENHI-PROJECT-23590257, KAKENHI-PROJECT-23590344, KAKENHI-PROJECT-23659170, KAKENHI-PROJECT-24390051, KAKENHI-PUBLICLY-23116509
[Journal Article] クラスII型PI3キナーゼC2αによる血管内皮シグナリング調節機能の蛍光ライブイメージング解析2013
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和陽
- Journal Title
  
  日本血栓止血学会誌特集「血管内皮、血管機能のイメージング解析」
  
  Volume: 24(6) Pages: 560-568
- NAID
  130003393318
- Data Source
  KAKENHI-PROJECT-23590257
[Journal Article] PI3キナーゼ・ファミリーの血管における生理機能: クラスIIα型PI3キナーゼC2αによる新たな血管恒常性維持機構2013
- Author(s)
  吉岡和晃, 吉田耕太郎, 多久和典子, 岡本安雄, 多久和陽
- Journal Title
  
  血管「総説」
  
  Volume: 36(2) Pages: 53-61
- NAID
  10031177130
- Data Source
  KAKENHI-PROJECT-23590257
[Journal Article] P13キナーゼ・ファミリーの血管における生理機能:クラスIIα型P13キナーゼC2aによる新たな血管恒常性維持機構2013
- Author(s)
  吉岡和晃
- Journal Title
  
  血管
  
  Volume: 36 Pages: 1-9
- Data Source
  KAKENHI-PROJECT-24390051
[Journal Article] Aldosterone inhibits endothelial morphogenesis and angiogenesis through the downregulation of vascular endothelial growth factor receptor-2 expression subsequent to peroxisome proliferator-activated receptor gamma.2012
- Author(s)
  Fujii M, Konoshita T et al.
- Journal Title
  
  J Steroid Biochem Mol Biol
  
  Volume: 129 Issue: 3-5 Pages: 145-152
- DOI
  10.1016/j.jsbmb.2011.12.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590909, KAKENHI-PROJECT-23590257
[Journal Article] Essential role of endothelial class II PI3K-C2α in angiogenesis and vascular barrier function2012
- Author(s)
  Yoshioka K, Yoshida K, Cui H, Wakayama T, Takuwa N, Okamoto Y, Du W, Qi X, Asanuma K, Sugihara K, Aki S, Miyazawa H, Biswas K, Nagakura C, Ueno M, Iseki S, Schwartz J.R, Okamoto H, Sasaki T, Matsui O, Asano M, Adams H.R, Takakura N, Takuwa Y
- Journal Title
  
  Nature med
  
  Volume: 18(10) Pages: 1560-1569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659170
[Journal Article] Essential role of endothelial class II PI3K-C2αin angiogenesis and vascular barrier function2012
- Author(s)
  Yoshioka K, Yoshida K, Cui H, Wakayama T, Takuwa N, Okamoto Y, Du W, Qi X, Asanuma K, Sugihara K, Aki S, Miyazawa H, Biswas K, Nagakura C, Ueno M, Iseki S, Schwartz JR, Okamoto H, Sasaki T,Matsui O, Asano M, Adams HR, Takakura N, Takuwa Y.
- Journal Title
  
  Nature med
  
  Volume: 18 Issue: 10 Pages: 1560-1569
- DOI
  10.1038/nm.2928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590284, KAKENHI-PROJECT-23500493, KAKENHI-PROJECT-23590257, KAKENHI-PROJECT-23590344, KAKENHI-PROJECT-23659170, KAKENHI-PROJECT-24300330, KAKENHI-PROJECT-24390051, KAKENHI-PLANNED-22112005, KAKENHI-PUBLICLY-23116509
[Journal Article] Sphingosine-1-phosphate signaling in physiology and diseases2012
- Author(s)
  Takuwa Y
- Journal Title
  
  BioFactors
  
  Volume: 38 Issue: 5 Pages: 329-337
- DOI
  10.1002/biof.1030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590284, KAKENHI-PROJECT-23590257, KAKENHI-PROJECT-23590344, KAKENHI-PROJECT-23659170, KAKENHI-PUBLICLY-23116509
[Journal Article] Overexpression of sphingosine kinase 1 prevents ceramide accumulation and ameliorates muscle insulin resistance in high fat-fed mice.2012
- Author(s)
  Bruce CR, Risis S, Babb JR, Yang C, Kowalski GM, Selathurai A, Lee-Young RS, Weir JM, Yoshioka K, Takuwa Y, Meikle PJ, Pitson SM and Febbraio MA
- Journal Title
  
  Diabetes
  
  Volume: 61 Issue: 12 Pages: 3148-3155
- DOI
  10.2337/db12-0029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590257, KAKENHI-PROJECT-23659170, KAKENHI-PUBLICLY-23116509
[Journal Article] G Protein-coupledsphingosine-1-phosphate receptors: potential molecular targets for angiogenic and anti-angiogenic therapies2011
- Author(s)
  Takuwa N, Okamoto Y, Yoshioka K, Takuwa Y
- Journal Title
  
  Biomed Rev
  
  Volume: 22 Pages: 15-29
- URL
  http://www.eurochicago.com/wp-content/uploads/2012/03/BMR-22-2011.pdf#page=22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659170
[Journal Article] Tumor-promoting Sphingosine-1-phosphate Receptor-1 and Sphingosine Kinase 1-Jekyll Hidden behind Hyde.2011
- Author(s)
  Takuwa N, Du W, Kaneko E, Okamoto Y, Yoshioka K Takuwa Y.
- Journal Title
  
  Am J Cancer Res.
  
  Volume: 1 Pages: 460-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590257
[Journal Article] Tumor-suppressive Sphingosine-1-phosphate Receptor-2 Counteracting Tumor-promoting Sphingosine-1-phosphate Receptor-1 and Sphingosine Kinase 12011
- Author(s)
  Takuwa N, Du W, Kaneko E, Okamoto Y, Yoshioka K, Takuwa Y
- Journal Title
  
  AM.J.Cancer.Res
  
  Volume: 12 Pages: 460-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] G Protein-coupled sphingosine-1-phosphate receptors: potential molecular targets for angiogenic and anti-angiogenic therapies.2011
- Author(s)
  Takuwa N, Okamoto Y, Yoshioka K, Takuwa Y.
- Journal Title
  
  Biomed Rev.
  
  Volume: 22 Pages: 15-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590257
[Journal Article] S1Pシグナル伝達系の心血管系における機能2011
- Author(s)
  岡本安雄、吉岡和晃、多久和典子、多久和陽
- Journal Title
  
  生化学ミニレビュー
  
  Volume: 83 Pages: 536-544
- Data Source
  KAKENHI-PROJECT-23590257
[Journal Article] Tumor-suppressive Sphingosine-1-phosphate Receptor-2 Counteracting Tumor-promoting Sphingosine-1-phosphate Receptor-1 and Sphingosine Kinase 1-Jekyll Hidden behind Hyde2011
- Author(s)
  Takuwa N, Du W, Kaneko E, Okamoto Y, Yoshioka K , Takuwa Y
- Journal Title
  
  AmJCancerRes
  
  Volume: 1 (4) Pages: 460-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590257
[Journal Article] Sphingosine-1-Phosphate-Specific G Protein-Coupled Receptors asNovel Therapeutic Targets for Atherosclerosis2011
- Author(s)
  Y Okamoto, F Wang, K Yoshioka, N Takuwa Y, Takuwa
- Journal Title
  
  Pharmaceuticals
  
  Volume: 4 Pages: 117-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] G Protein-coupled sphingosine-1-phosphate receptors : potential molecular targets for angiogenic and anti-angiogenic therapies2011
- Author(s)
  Takuwa N, Okamoto Y, Yoshioka K, Takuwa Y
- Journal Title
  
  BiomedRev
  
  Volume: 22 Pages: 15-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590257
[Journal Article] Sphingosine-1-Phosphate-Specific G Protein-Coupled Receptors as Novel Therapeutic Targets for Atherosclerosis2011
- Author(s)
  Okamoto Y, Wang F, Yoshioka K , Takuwa N., Takuwa Y
- Journal Title
  
  Pharmaceuticals
  
  Volume: 4 Pages: 117-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590257
[Journal Article] Tumor-suppressive Sphingosine-1-phosphate Receptor-2 Counteracting Tumor-promoting Sphingosine-1-phosphate Receptor-1 and Sphingosine Kinase 1-Jekyll Hidden behind Hyde2011
- Author(s)
  Takuwa N, Du W, Kaneko E, Okamoto Y, Yoshioka K Takuwa Y
- Journal Title
  
  Am J Cancer Res.
  
  Volume: 1(4) Pages: 460-481
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186046/?tool=pubmed
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659170
[Journal Article] Protein-coupled sphingosine-1-phosphate receptors : potential molecular targets for angiogenic and anti-angiogenic therapies2011
- Author(s)
  Takuwa N, Okamoto Y, Yoshioka K, Takuwa Y.
- Journal Title
  
  Biomed Rev
  
  Volume: 22 Pages: 15-29
- URL
  http://www.eurochicago.com/wp-content/uploads/2012/03/BMR-22-2011.pdf#page=22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] Tumor-suppressive Sphingosine-1-phosphate Receptor-2 Counteracting Tumor-promoting Sphingosine-1-phosphate Receptor-1 and Sphingosine Kinase 1-Jekyll Hidden behind Hyde2011
- Author(s)
  Takuwa N, Du W, Kaneko E, Okamoto Y, Yoshioka K Takuwa Y.
- Journal Title
  
  Am J Cancer Res
  
  Volume: 1(4) Pages: 460-481
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186046/?tool=pubmed
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] Sphingosine-1-Phosphate-Specific G Protein-Coupled Receptors as Novel Therapeutic Targets for Atherosclerosis Pharmaceuticals2011
- Author(s)
  Okamoto Y, Wang F, Yoshioka K, Takuwa N, Takuwa Y.
- Journal Title
  
  Atherosclerosis Pharmaceuticals
  
  Volume: 4 Issue: 1 Pages: 117-137
- DOI
  10.3390/ph4010117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] PI3キナーゼ・ファミリーの細胞内情報伝達機構2010
- Author(s)
  吉岡和晃、多久和陽
- Journal Title
  
  金沢大学十全医学会雑誌
  
  Volume: 119 Pages: 51-55
- NAID
  10027445135
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in Apoe-deficient mice.2010
- Author(s)
  Wang F, Okamoto Y, Inoki I, Yoshioka K, et al.
- Journal Title
  
  J.Clin.Invest. 120
  
  Pages: 3979-3995
- NAID
  120002511714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species2010
- Author(s)
  Takuwa N, Ohkura S, Takashima S, Ohtani K, Okamoto Y, Tanaka T, Hirano K, Usui S, Wang F, Du W, Yoshioka K, Banno Y, Sasaki M, Ichi I, Okamura M, Sugimoto N, Mizugishi K, Nakanuma Y, Ishii I, Takamura M, Kaneko S, Kojo S, Satouchi K, Mitumori K, Chun J, Takuwa Y
- Journal Title
  
  Cardiovasc Res
  
  Volume: 85(3) Issue: 3 Pages: 484-493
- DOI
  10.1093/cvr/cvp312
- NAID
  120001939472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057, KAKENHI-PROJECT-21591414, KAKENHI-PROJECT-22590284
[Journal Article] Sphingosine-1-Phosphate-Specific G Protein-Coupled Receptors as Novel Therapeutic Targets for Atherosclerosis.2010
- Author(s)
  Y Okamoto, F Wang, K Yoshioka, N Takuwa, Y Takuwa
- Journal Title
  
  Pharmaceuticals 4
  
  Pages: 117-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice2010
- Author(s)
  Qi X, Okamoto Y, Murakawa T, Wang F, Oyama O, Ohkawa R, Yoshioka K, Du W, Sugimoto N, Yatomi Y, Takuwa N, Takuwa Y.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 634(1-3) Issue: 1-3 Pages: 121-131
- DOI
  10.1016/j.ejphar.2010.02.038
- NAID
  120002086439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057, KAKENHI-PROJECT-22590284
[Journal Article] Enhanced Ca^<2+>-Dependent Activation of Phosphoinositide 3-Kinase Class IIα Isoform-Rho Axis in Blood Vessels of Spontaneously Hypertensive Rats.2010
- Author(s)
  Young M-S, Azam MA, Okamoto Y, Sato A, Yoshioka K, et al.
- Journal Title
  
  Hypertenion 56
  
  Pages: 934-941
- NAID
  120002661948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice.2010
- Author(s)
  Qi X, Okamoto Y, Murakawa T, Wang F, Oyama O, Ohkawa R, Yoshioka K, et al.
- Journal Title
  
  Eur.J.Pharmacol. 634
  
  Pages: 121-131
- NAID
  120002086439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] PI3 キナーゼ・ファミリーの細胞内情報伝達機構2010
- Author(s)
  吉岡和晃、多久和陽
- Journal Title
  
  金沢大学十全医学会雑誌 119
  
  Pages: 51-55
- NAID
  10027445135
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] Enhanced Ca^<2+>-Dependent Activation of Phosphoinositide 3-Kinase Class IIα Isoform-Rho Axis in Blood Vessels of Spontaneously Hypertensive Rats2010
- Author(s)
  Young M-S, Azam MA, Okamoto Y, Sato A, Yoshioka K, et al
- Journal Title
  
  Hypertenion
  
  Volume: 56 Pages: 934-941
- NAID
  120002661948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] Roles of sphingosine-1-phosphate signaling in angiogenesis2010
- Author(s)
  Takuwa Y, Du W, Qi X, Okamoto Y, Takuwa N, Yoshioka K.
- Journal Title
  
  World J Biol Chem
  
  Volume: 1(10) Pages: 298-306
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083935/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in Apoe-deficient mice2010
- Author(s)
  Wang W, Okamoto Y, Inoki I, Yoshioka K, et al
- Journal Title
  
  J.Clin.Invest
  
  Volume: 120 Pages: 3979-3995
- NAID
  120002511714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species2010
- Author(s)
  Takuwa N, Ohkura S, TakashimaS, Ohtani K, Okamoto Y, Tanaka T, Hirano K, Usui S, Wang F, Du W, Yoshioka K, et al
- Journal Title
  
  Cardiovasc.Res
  
  Volume: 85 Pages: 484-493
- NAID
  120001939472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species.2010
- Author(s)
  Takuwa N, Ohkura S, Takashima S, Ohtani K, Okamoto Y, Tanaka T, Hirano K, Usui S, Wang F, Du W, Yoshioka K, et al.
- Journal Title
  
  Cardiovasc.Res. 85
  
  Pages: 484-493
- NAID
  120001939472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] Tumor-suppressive Sphingosine-1-phosphate Receptor-2 Counteracting Tumor-promoting Sphingosine-1-phosphate Receptor-1 and Sphingosine Kinase 1.2010
- Author(s)
  Takuwa N, Du W, Kaneko E, Okamoto Y, Yoshioka K, Takuwa Y
- Journal Title
  
  Am J Cancer Res. 1
  
  Pages: 460-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] S1P(2), the G protein-coupled receptor for sphingosine-1-phosphate, negatively regulates tumor angiogenesis and tumor growth in vivo in mice2010
- Author(s)
  Du W, Takuwa N, Yoshioka K, et al
- Journal Title
  
  Cancer Res
  
  Volume: 70 Pages: 772-781
- NAID
  120001939471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] S1P2, the G protein-coupledreceptor for sphingosine-1-phosphate, negatively regulates tumor angiogenesis and tumor growth in vivo in mice2010
- Author(s)
  Du W, Takuwa N, Yoshioka K, Okamoto Y, Gonda K, Sugihara K, Fukamizu A, Asano M, Takuwa Y.
- Journal Title
  
  Cancer Res
  
  Volume: 70(2) Issue: 2 Pages: 772-781
- DOI
  10.1158/0008-5472.can-09-2722
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057, KAKENHI-PROJECT-22590284
[Journal Article] S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species.2010
- Author(s)
  N. Takuwa, S. Ohkura, S. Takashima, K. Ohtani, Y. Okamoto, T. Tanaka, K, Hirano, S. Usui, F. Wang, W. Du, K. Yoshioka, Y. Banno, M. Sasaki, I. Ichi, M. Okamura, N. Sugimoto, K. Mizugishi, Y. Nakanuma, I. Ishii, M. Takamura, S. Kaneko, S. Kojo, K. Satouchi, K. Mitumori, J. Chun, Y. Takuwa
- Journal Title
  
  Cardiovasc Res 85(3)
  
  Pages: 484-493
- NAID
  120001939472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Roles of sphingosine-1-phosphate signaling in angiogenesis2010
- Author(s)
  Takuwa Y, Du W, Qi X, Okamoto Y, Takuwa N, Yoshioka K
- Journal Title
  
  World J Biol Chem
  
  Pages: 298-306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] S1P(2), the G protein-coupled receptor for sphingosine-1-phosphate, negatively regulates tumor angiogenesis and tumor growth in vivo in mice.2010
- Author(s)
  杜娃, 多久和典子, 吉岡和晃, et al.
- Journal Title
  
  Cancer Res. 70
  
  Pages: 772-781
- NAID
  120001939471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] Roles of sphingosine-1-phosphate signaling in angiogenesis.2010
- Author(s)
  多久和陽, 杜娃, 戚〓, 岡本安雄, 多久和典子, 吉岡和晃
- Journal Title
  
  World J Biol Chem. 1
  
  Pages: 298-306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] Enhanced Ca2+-Dependent Activation of PI3KC2 alpha Rho Axis in Blood Vessels of Spontaneously Hypertensive Rats2010
- Author(s)
  Seok YM, Azam MA, Okamoto Y, Sato A, Yoshioka K, Maeda M, Kim IK, Takuw Y.
- Journal Title
  
  Hypertension
  
  Volume: 56(5) Issue: 5 Pages: 934-941
- DOI
  10.1161/hypertensionaha.110.160853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057, KAKENHI-PROJECT-22590284
[Journal Article] Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediatedangiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice2010
- Author(s)
  Qi X, Okamoto Y, Murakawa T, Wang F, Oyama 0, Ohkawa R, Yoshioka K, et al
- Journal Title
  
  Eur.J.Pharmacol
  
  Volume: 634 Pages: 121-131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] Y Takuwa S1P2, the G protein-coupled receptor for sphingosine-1-phosphate, negatively regulates tumor angiogenesis and tumor growth in vivo in mice.2010
- Author(s)
  W Du, N Takuwa, K Yoshioka, Y Okamoto, K Gonda, K Sugihara, A Fukamizu, M Asano
- Journal Title
  
  Cancer Res 70(2)
  
  Pages: 772-781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice.2010
- Author(s)
  X Qi, Y Okamoto, T Murakawa, F Wang, O Oyama, R Ohkawa, K Yoshioka, W Du, N Sugimoto, Y Yatomi, N Takuwa, Y Takuwa
- Journal Title
  
  Eur J Pharmacol 634
  
  Pages: 121-131
- NAID
  120002086439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] The role of class II PI3-kinase signaling pathway in physiology and diseases.2009
- Author(s)
  多久和陽, 吉岡和晃, 岡本安雄, 多久和典子
- Journal Title
  
  Curr Biodata Targeted Proteins Database 1,[22910],10.2970/tpdb.2009
  
  Pages: 246-246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] 生体におけるスフィンゴシン-1-リン酸シグナル系の機能2009
- Author(s)
  多久和陽、岡本安雄、杜娃、戚〓、吉岡和晃、多久和典子
- Journal Title
  
  実験医学(特集情報伝達をつかさどる生理活性物質脂質メディエーターの機能) 27(13)
  
  Pages: 2068-2073
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] 生体におけるスフィンゴシン-1-リン酸シグナル系の機能2009
- Author(s)
  多久和陽、岡本安雄、杜娃、戚〓、吉岡和晃、多久和典子
- Journal Title
  
  実験医学 27(13)
  
  Pages: 2068-2073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependenton Rho but not Rho kinase.2008
- Author(s)
  S. Takashima, N. Sugimoto, N. Takuwa, Y. Okamoto, K. Yoshioka, M. Takamura, S. Takata, S. Kanekob, Y. Takuwa
- Journal Title
  
  Cardiovasc Res 79(4)
  
  Pages: 689-697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Rho-ROCKと平滑筋収縮2008
- Author(s)
  多久和陽、吉岡和晃、岡本安雄
- Journal Title
  
  眼薬理(シンポジウムI緑内障薬物治療の未来) 22
  
  Pages: 34-36
- NAID
  10025687182
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] Sphingosine-1-phosphatesignaling and biological activitiesin the cardiovascular system.2008
- Author(s)
  Y. Takuwa, Y. Okamoto, K. Yoshioka, N. Takuwa
- Journal Title
  
  Biochim. Biophys. Acta 1781(9)
  
  Pages: 483-488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system.2008
- Author(s)
  多久和陽, 岡本安雄, 吉岡和晃, 多久和陽
- Journal Title
  
  Biochem.Biophys.Acta 1781
  
  Pages: 483-488
- NAID
  120001130403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] カルシウムによるRho-Rhoキナーゼを介したミオシン軽鎖ホスファターゼ制御におけるクラスII型PI3キナーゼC2αの役割2008
- Author(s)
  吉岡和晃、多久和陽、岡本安雄
- Journal Title
  
  血管医学(メディカルレビュー社特集:血管収縮制御の分子機構) 9(2)
  
  Pages: 223-230
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] G_<12/13> and G_q mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase.2008
- Author(s)
  Takashima S, Sugimoto N, Takuwa N, Okamoto Y, Yoshioka, K., et al.
- Journal Title
  
  Cardiovas.Res. 79
  
  Pages: 689-697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590207
[Journal Article] Essential role for class II phosphoinositide 3-kinase alpha-isoform in Ca2+-induced, Rhoand Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells.2007
- Author(s)
  K. Yoshioka, N. Sugimoto, N. Takuwa, Y. Takuwa
- Journal Title
  
  Mol Pharmacol 71(3)
  
  Pages: 912-920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Essential role for class II phosphoinositide 3-kinase alpha-isoform in Ca2+-induced, Rho-and Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells.2007
- Author(s)
  K.Yoshioka, N.Sugimoto, N.Takuwa, Y.Takuwa
- Journal Title
  
  Mol Pharmacol. 71(3)
  
  Pages: 912-920
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Essential role for class II phosphoinositide 3-kinase alpha-isoform in Ca2+-induced, Rho-and Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells.2007
- Author(s)
  K. Yoshioka
- Journal Title
  
  Mol Pharmacol 71
  
  Pages: 912-920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Essential role for class II phosphoinositide 3-kinase alpha-isoform in Ca2+-induced, Rho- and Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells.2007
- Author(s)
  Kazuaki Yoshioka
- Journal Title
  
  Mol Pharmacol. 71(3)
  
  Pages: 912-920
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Essential role for class II phosphoinositide 3-kinase alpha-isoform in Ca2+-induced, Rho^- and Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells.2007
- Author(s)
  Yoshioka Kazuaki
- Journal Title
  
  Mol Pharmacol 71(3)
  
  Pages: 912-920
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Essential role for class II phosphoinositide 3-kinase alpha-isoform in Ca2+-induced, Rho-and Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells.2007
- Author(s)
  Yoshioka Kazuaki
- Journal Title
  
  Mol Pharmacol. 71(3)
  
  Pages: 912-920
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Ca2+-independent, inhibitory effects of cyclic AMP on Ca2+ regulation of phosphoinositide 3-kinase C2a, Rho and myosin phosphatase in vascular smooth muscle2007
- Author(s)
  MA. Azam, K. Yoshioka, S. Ohkura, N. Takuwa, N. Sugimoto, K. Sato, Y. Takuwa
- Journal Title
  
  J. Pharm. Exp. Ther 320(2)
  
  Pages: 907-916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Ca2+-independent, inhibitory effects of cyclic AMP on Ca2+ regulation of phosphoinositide 3-kinase C2a, Rho and myosin phosphatase in vascular smooth muscle.2006
- Author(s)
  MA.Azam, K.Yoshioka, S.Ohkura, N.Takuwa, N.Sugimoto, K.Sato, Y.Takuwa
- Journal Title
  
  J. Pharm.Exp.Ther 320(2)
  
  Pages: 907-916
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Takuwa Negative regulation of endothelial morphogenesis and angiogenesis by S1P2 receptor.2006
- Author(s)
  I.Inoki, N.Takuwa, N.Sugimoto, K.Yoshioka, S.Takata, S.Kaneko, Y.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Takuwa Class II phosphoinositide 3-kinase alfa-isoform regulates Rho, myosin phosphatase and contraction in vascular smooth muscle.2006
- Author(s)
  Y.Wang, K.Yoshioka, MA.Azam, N.Takuwa, S.Sakurada, Y.Kayaba, N.sugimoto, I.Inoki, T.Kimura, T.Kuwai, Y.
- Journal Title
  
  Biochem J 394
  
  Pages: 581-592
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Negative regulation of endothelial morphogenesis and angiogenesis by S1P2 receptor.2006
- Author(s)
  I. Inoki, N. Takuwa, N. Sugimoto, K. Yoshioka, S. Takata, S. Kaneko, Y. Takuwa
- Journal Title
  
  Biochem. Biophys. Res. Commun. 346
  
  Pages: 293-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Class II phosphoinositide 3-kinase α-isoform regulates Rho, myosin phosphatase and contraction in vascular smooth muscle2006
- Author(s)
  Yu WANG, Kazuaki YOSHIOKA, Mohammed Ali AZAM, Noriko TAKUWA, Sotaro SAKURADA, Yuji KAYABA, Naotoshi SUGIMOTO, Isao INOKI, Takaharu KIMURA, Tomoyuki KUWAKI, Yoh TAKUWA
- Journal Title
  
  Biochemical Journal 394
  
  Pages: 581-592
- Data Source
  KAKENHI-PROJECT-16790133
[Journal Article] Rho-dependent, Rho kinase-independent inhibitory regulation of Rac and cell migration by LPA1 receptor in Gi-inactivated CHO sells.2006
- Author(s)
  N.Sugimoto, N.Takuwa, K.Yoshioka, Y.Takuwa
- Journal Title
  
  Exp. Cell Res. 312
  
  Pages: 1899-1908
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Sugimoto Calcium-dependent regulation of Rho and myosin phosphatase in vascular smooth muscle.2005
- Author(s)
  Y.Takuwa, K.Yoshioka, N.Takuwa, Y.Wang, MA.Azam, N.
- Journal Title
  
  Biomed. Res. 16
  
  Pages: 13-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Calcium-dependent regulation of Rho and myosin phosphatase in vascular smooth muscle2005
- Author(s)
  Yoh Takuwa, Kazuaki Yoshioka, Noriko Takuwa, Yu Wang, Mohammed Ali Azam, Naotoshi Sugimofo
- Journal Title
  
  Biomedical Review 16
  
  Pages: 1-9
- Data Source
  KAKENHI-PROJECT-16790133
[Journal Article] 脳血管攣縮と活性酸素
- Author(s)
  多久和陽、吉岡和晃、岡本安雄
- Journal Title
  
  血管医学(メディカルレビュー社特集:血管収縮制御の分子機構) 9(2)
  
  Pages: 269-274
- Data Source
  KAKENHI-PROJECT-20590207
[Patent] 非ヒトノックアウト動物、並びにその用途およびその作製方法2011
- Inventor(s)
  多久和陽、吉岡和晃
- Industrial Property Rights Holder
  国立大学法人金沢大学
- Industrial Property Number
  2010-090078
- Filing Date
  2011-04-09
- Data Source
  KAKENHI-PROJECT-17014034
[Patent] 非ヒトノックアウト動物、並びによの用途およびその作製方法2010
- Inventor(s)
  吉岡和晃多久和陽
- Industrial Property Rights Holder
  吉岡和晃多久和陽
- Industrial Property Number
  2010-090078
- Filing Date
  2010-04-09
- Data Source
  KAKENHI-PROJECT-20590207
[Patent] 非ヒトノックアウト動物、並びにその用途およびその作製方法2010
- Inventor(s)
  吉岡和晃、多久和陽
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Number
  2010-090078
- Filing Date
  2010-04-09
- Data Source
  KAKENHI-PROJECT-20590207
[Patent] 非ヒトノックアウト動物、並びにその用途およびその作製方法2010
- Inventor(s)
  吉岡和晃、多久和陽
- Industrial Property Rights Holder
  国立大学法人金沢大学
- Filing Date
  2010-04-09
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] 褐色脂肪組織におけるスフィンゴシンキナーゼ1の機能解析2023
- Author(s)
  盛重純一，吉岡和晃，長田直人，田中保，多久和陽，安藤仁
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K10866
[Presentation] Single cell transcriptome analysis of adventitial vasa vasorum remodeling in human aortic dissection2023
- Author(s)
  吉岡和晃、飯野賢治、射場智大、松居　彩、内藤尚道
- Organizer
  第100回日本生理学会（京都）
- Data Source
  KAKENHI-PROJECT-20K07273
[Presentation] 血管新生因子TGFb/Smadシグナリングを制御するホスホイノシタイドカスケード2021
- Author(s)
  安藝翔、吉岡和晃、加藤美樹、前田啓介、中原龍一、土田里香、多久和陽、大澤毅
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-20K07273
[Presentation] 褐色脂肪組織におけるスフィンゴシンキナーゼ1の機能解析2021
- Author(s)
  盛重　純一，吉岡　和晃，田中　保，多久和　陽，安藤　仁
- Organizer
  第63回脂質生化学会
- Data Source
  KAKENHI-PROJECT-20K11601
[Presentation] TGFβ receptor endocytosis and Smad signaling require synaptojanin1, PI3K-C2α, and INPP4B-mediated phophoinositide conversions2021
- Author(s)
  Aki S, Yoshioka K, Takuwa N, Takuwa Y
- Organizer
  2020年度第98回日本生理学会
- Data Source
  KAKENHI-PROJECT-20K07273
[Presentation] クラス II-PI3 キナーゼによるエンドサイトーシス制御を介した血管平滑筋収縮調節機構2021
- Author(s)
  吉岡和晃、Shahidul Islam、安藝翔、石丸和宏、多久和典子、多久和陽
- Organizer
  第63回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-20K07273
[Presentation] Class II phosphatidylinositol 3-kinase α and β isoforms are required for vascular smooth muscle Rho activation, contraction and blood pressure regulation in mice2021
- Author(s)
  Shahidul Islam, Kazuaki Yoshioka, Sho Aki, Kazuhiro Ishimaru, Hiroki Yamada, Noriko Takuwa & Yoh Takuwa
- Organizer
  2020年度第98回日本生理学会（第11回　入澤宏・彩記念JPS優秀論文）
- Invited
- Data Source
  KAKENHI-PROJECT-20K07273
[Presentation] Sphingosine kinase-2 is required for autophagic lipid degradation in macrophage and inhibits atherosclerosis2020
- Author(s)
  Yoh Takuwa, Kazuhiro Ishimaru, Kazuaki Yoshioka, Noriko Takuwa, Yasuo Okamoto
- Organizer
  第９７回　日本生理学会大会（大分・別府）
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] Sequential phosphoinositide conversion is required for TGFβ-induced receptor endocytosis and endosomal receptor signaling in endothelial cells2020
- Author(s)
  Sho Aki, Kazuaki Yoshioka, Noriko Takuwa, Yoh Takuwa
- Organizer
  第９７回　日本生理学会大会（大分・別府）
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] Differential roles of class II PI3-kinase-C2α and -C2β in clathrinmediated fluid phase endocytosis in vascular endothelial cells2020
- Author(s)
  Kazuaki Yoshioka, Sho Aki, Noriko Takuwa, Yoh Takuwa
- Organizer
  第９７回　日本生理学会大会（大分・別府）
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] 連続するホスホイノシタイド代謝がTGFβ受容体エンドサイトーシス及びSmad2/3活性化に必須である2019
- Author(s)
  安藝　翔、吉岡和晃、Islam Shahidul、多久和典子、多久和　陽
- Organizer
  第92回日本生化学会大会、横浜パシフィコ（横浜）
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] 細胞膜イノシトールリン脂質脱リン酸化酵素・MTMR4による細胞内クリアランスの制御2019
- Author(s)
  吉岡和晃、Quynh Hoa Pham、安藝　翔、多久和典子、多久和　陽
- Organizer
  第92回日本生化学会大会、横浜パシフィコ（横浜）
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] イノシトールリン脂質3’脱リン酸化酵素MTMR4 による細胞内クリアランス制御メカニズム2019
- Author(s)
  吉岡和晃、Quynh Hoa Pham、安藝　翔、多久和典子、多久和　陽
- Organizer
  第61回日本脂質生化学会、北海道大学（札幌）
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] Differential roles of class II PI3K in endocytosis and endosomal signaling2019
- Author(s)
  Kazuaki Yoshioka, Khin Thuzar Aung, Md Azadul Kabir Sarker, Sho Aki, Kuntal Biswas, Noriko Takuwa, Yoh Takuwa
- Organizer
  60th International Conference on the Bioscience of Lipids, Hitotsubashi Hall (Tokyo)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] Sequential phosphoinositide conversion is required for transforming growth factor β-induced receptor endocytosis and Smad2/3 activation in endothelial cells2019
- Author(s)
  Sho Aki, Kazuaki Yoshioka, Noriko Takuwa, Yoh Takuwa
- Organizer
  60th International Conference on the Bioscience of Lipids, Hitotsubashi Hall (Tokyo)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] 連続するホスホイノシタイド代謝がTGFβ受容体エンドサイトーシス及びSmad2/3 活性化に必須である2019
- Author(s)
  安藝　翔、吉岡和晃、多久和典子、多久和　陽
- Organizer
  第61回日本脂質生化学会、北海道大学（札幌）
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] ノシトールリン脂質3’-ホスファターゼMTMR4によるエンド-リソソームおよびオートファジー経路の制御メカニズム2019
- Author(s)
  吉岡和晃、Quynh Hoa Pham、安藝　翔、多久和　陽
- Organizer
  日本生化学会北陸支部第37回大会、ハルピン・ホール（福井）
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] Sequential phosphoinositide conversion is required for TGFβ-induced receptor endocytosis in ECs.2019
- Author(s)
  Aki, S., Yoshioka, K., Takuwa, N., Takuwa, Y.
- Organizer
  9th Federation of the Asia and Oceanian Physiological Societies (FAOPS2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] 血管内皮細胞のDll4-Notch シグナルにおけるクラスII型PI3 キナーゼ-C2α の機能2019
- Author(s)
  清水奨太、吉岡和晃、安藝　翔、多久和　陽
- Organizer
  日本生化学会北陸支部第37回大会、ハルピン・ホール（福井）
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] Essential role of class II PI3K in endocytosis and endosomal signaling.2019
- Author(s)
  Yoshioka, K., Aung, KT., Sarker, Md.A.K., Aki, S., Biswas, K., Takuwa, N., Takuwa, Y.
- Organizer
  9th Federation of the Asia and Oceanian Physiological Societies (FAOPS2019)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] Class II phosphoinositide 3-kinase isoforms PI3K-C2αand PI3K-C2β play essential roles in pinocytosis in vascular endothelial cells.2018
- Author(s)
  Aung Thuzar Khin, Yoshioka Kazuaki, Aki Sho, Pham Quynh Hoa, Sarker Kabir Azadul, Islam Shahidul, Ishimaru Kazuhiro, Takuwa Noriko, Takuwa Yoh
- Organizer
  第 95 回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] Indispensable role of α and β isoforms of class II phosphoinositide 3-kinases (PI3K) in the uterine smooth muscle contraction during labor2018
- Author(s)
  Sarker Kabir Azadul, Sho Aki, Yoshioka Kazuaki, Kuno Koji, Okamoto Yasuo, Aung Thuzar Khin, Pham Quynh Hoa, Islam Shahidul, Takuwa Noriko, Takuwa Yoh
- Organizer
  第 95 回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] Myotubularin-related protein 4 (MTMR4), a phosphoinositide 3'-phosphatase, regulates endolysosome integrity and autophagy flux in human lung alveolar epithelial A549 cells2018
- Author(s)
  Pham Quynh Hoa, Yoshioka Kazuaki, Azadul Sarker Kabir, Aung Thuzar Khin, Islam Shahidul, Aki Sho, Ishimaru Kazuhiro, Takuwa Noriko, Takuwa Yoh
- Organizer
  第 95 回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] Endothelial Class II PI3K-C2α is necessary for vascular formation and integrity through regulating endocytic membrane trafficking2017
- Author(s)
  吉岡和晃、安藝　翔、多久和典子、多久和　陽
- Organizer
  第81回日本循環器学会学術集会
- Place of Presentation
  金沢市
- Year and Date
  2017-03-16
- Invited
- Data Source
  KAKENHI-PROJECT-26460292
[Presentation] クラスII型PI3K-C2α及びPI3K-C2βは血管血管内皮細胞におけるピノサイトーシスに必須である2017
- Author(s)
  Khin Thuzar Aung, Sho Aki, Kazuaki Yoshioka, Hoa Quynh Pham, Azadul Kabir Sarker, Shahidul Islam, Noriko Takuwa and Yoh Takuwa
- Organizer
  第94 回日本生理学会大会
- Place of Presentation
  浜松市
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-26460292
[Presentation] イノシトールリン脂質特異的3’-ホスファターゼMTMR4はリソソーム機能・オートファジーを制御する2017
- Author(s)
  Hoa Quynh Pham, Kazuaki Yoshioka, Sato Nakamura, Azadul Kabir Sarker, Khin Thuzar Aung, Shahidul Islam, Sho Aki, Noriko Takuwa and Yoh Takuwa
- Organizer
  第94 回日本生理学会大会
- Place of Presentation
  浜松市
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-26460292
[Presentation] Myotubularin-related protein 4 (MTMR4), a phosphoinositide 3'-speciphosphatase, regulates endolysosome integrity and autophagy in A549 human lung carcinoma cells.2017
- Author(s)
  Quynh Hoa Pham , Kazuaki Yoshioka , Azadul Kabir Sarker , Khin Thuzar Aung , Shahidul Islam , Sho Aki , Sato Nakamura , Noriko Takuwa, Yoh Takuwa
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08532
[Presentation] 血管内皮細胞においてクラスII 型PI3K-C2αはTGFβ/Smad シグナル伝達系に必須である2016
- Author(s)
  安藝　翔、吉岡和晃、岡本安雄、多久和　典子、多久和　陽
- Organizer
  第93回　日本生理学会
- Place of Presentation
  札幌コンベンションセンター（札幌市）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-26460292
[Presentation] クラス II PI3-キナーゼ PI3K-C2αはエンドソーム上でのTGFβ/Smad2/3シグナリングに必須である2015
- Author(s)
  安藝　翔、吉岡　和晃、岡本　安雄、多久和　典子、多久和　陽
- Organizer
  第62回中部日本生理学会
- Place of Presentation
  富山大学五福キャンパス　黒田講堂(富山県富山市)
- Year and Date
  2015-07-12
- Data Source
  KAKENHI-PROJECT-26460292
[Presentation] Role of S1P2 in inflammation and fibrosis2015
- Author(s)
  Yoh Takuwa Juanjuan Zhao, Yasuo, Okamoto, Kazuaki Yoshioka and Noriko Takuwa
- Organizer
  14 th International Conference on Bioactive Lipids in Cancer, Inflammation, and Related Diseases
- Place of Presentation
  Sofitel Chain Bridge Hotel（ハンガリー　ブタペスト）
- Year and Date
  2015-07-12
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460292
[Presentation] Sphingosine 1-phosphate receptor-2 plays a protective role against anaphylaxis and acute lung injury2015
- Author(s)
  Yasuo Okamoto, Hong Cui, Kazuaki Yoshioka, Noriko Takuwa, Yoh Takuwa
- Organizer
  第10回スフィンゴテラピィ（STC）研究会
- Place of Presentation
  ホテルアローレ（石川県）
- Year and Date
  2015-06-16
- Data Source
  KAKENHI-PROJECT-26460292
[Presentation] Deletion of sphingosine 1-phospahte (S1P) receptor-2 (S1P-2-) inhibits lung fibrosis through altering alveolar macrophage polarization and senescence in mice.2015
- Author(s)
  Juan juan Zhao Yasuo Okamoto Kazuaki Yoshioka Sho Aki Pham Quynh Hoa Azadul MD Kabir Sarker Khin Thuzar Aung Noriko Takuwa Yutaka Inagaki Chiaki Takahashi Takashi Wada Yoh Takuwa
- Organizer
  BMB2015（第38回日本分子生物学会・第88回日本生化学会）
- Place of Presentation
  神戸ポートアイランド（神戸ポートピアホテル　神戸国際会議場　神戸国際展示場　神戸商工会議所）(兵庫県神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460292
[Presentation] クラスII α型PI3K-C2αはエンドソーム上でのTGFβ/Smad2/3 シグナリングに必須である2015
- Author(s)
  安藝翔、吉岡和晃、岡本安雄、多久和典子、多久和陽
- Organizer
  第57回日本脂質生化学会
- Place of Presentation
  一橋大学一橋講堂（東京）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-26460292
[Presentation] クラスII 型PI3K-C2αはメンブレン・トラフィック調節を介して血管バリア機能を制御する2014
- Author(s)
  吉岡和晃，岡本安雄，多久和典子，多久和陽
- Organizer
  第91回日本生理学会大会　シンポジウム「心血管系の形態・機能研究の最前線」
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県鹿児島市）
- Invited
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] クラスII 型PI3K-C2αはメンブレン・トラフィック調節を介して血管バリア機能を制御する2014
- Author(s)
  吉岡和晃，岡本安雄，多久和典子，多久和陽
- Organizer
  第91回日本生理学会大会シンポジウム「心血管系の形態・機能研究の最前線」
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県鹿児島市）
- Invited
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] Sphingosine-1-phosphate receptor-2 protects against anaphylactic shock through inhibiting eNOS2014
- Author(s)
  Yasuo Okamoto, Hong Cui, Kazuaki Yoshioka, Noriko Takuwa, Juanjuan Zhao, Yoh Takuwa
- Organizer
  第91回日本生理学会大会 Symposium “Mechanisms on distributive shock and other blood pressure control failures”
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県鹿児島市）
- Invited
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] Sphingosine-1-phosphate receptor-2 protects against anaphylactic shock through inhibiting eNOS2014
- Author(s)
  Yasuo Okamoto, Hong Cui, Kazuaki Yoshioka, Noriko Takuwa, Juanjuan Zhao, Yoh Takuwa
- Organizer
  第91回日本生理学会大会　　Symposium “Mechanisms on distributive shock and other blood pressure control failures
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県鹿児島市）
- Invited
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Novel role of class II PI 3-kinase in in tumor angiogenesis2014
- Author(s)
  Yoshioka, K.
- Organizer
  International Symposium on Tumor Microenvironment. –Crosstalk between host and malignant cells
- Place of Presentation
  金沢大学・自然研図書館・AVホール(Kanazawa, Japan)
- Year and Date
  2014-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-26460292
[Presentation] Endothelial PI3K-C2a2013
- Author(s)
  Yoshioka K, Yoshida K, Biswas K, Takuwa Y, et al
- Organizer
  a class II PI3K, has an essential role in angiogenesis and vascular barrier function. Gordon Reseach Conference Vascular Cell Biology
- Place of Presentation
  Four Points Sheraton / Holiday Inn Express Express Ventura, (U.S.A)
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] クラスII型P13キナーゼC2aはメンブレン・トラフィツキング調節を介する血管形成及び恒常性維持に必須である2013
- Author(s)
  吉岡和晃
- Organizer
  第90回日本生理学会
- Place of Presentation
  タワーホール船堀(東京都)
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] TGFβ1-Smad2/3シグナル伝達系を介した血管新生調節におけるクラスIIαPI3キナーゼPI3K-C2αの機能的役割2013
- Author(s)
  安藝　翔、吉岡　和晃、多久和　典子、岡本　安雄、多久和　陽
- Organizer
  第21回日本血管生物医学会
- Place of Presentation
  千里阪急ホテル（大阪府豊中市）
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] クラスII型PI3キナーゼC2αはメンブレン・トラフィック調節を介する血管形成及び恒常性維持に必須である2013
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和　陽
- Organizer
  第９０回　日本生理学会大会
- Place of Presentation
  タワーホール船堀（東京）
- Invited
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] S1P2は内皮型一酸化窒素合成酵素を抑制することによりアナフラキシーショックに対して防御的に働く2013
- Author(s)
  岡本　安雄　崔　弘　吉岡　和晃　多久和　典子　多久和　陽
- Organizer
  第55回日本脂質生化学会
- Place of Presentation
  ホテル松島大観荘(宮城県宮城郡)
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] TGFβ1-Smad2/3シグナル伝達系を介した血管新生調節におけるクラスIIa型PI3キナーゼC2αの機能的役2013
- Author(s)
  安藝翔、吉岡和晃、岡本安雄、多久和典子、多久和陽
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2013-09-28
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] クラスII型PI3Kは血管恒常性維持、および血管形成に必須である。2013
- Author(s)
  吉岡和晃、岡本安雄、多久和陽
- Organizer
  新学術領域「自然炎症」「脂質マシナリー」合同若手ワークショップ
- Place of Presentation
  鳴門、徳島
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] クラスII 型PI3K-C2αはSARA のエンドソームへの動員を制御しTGFß1-Smad2/3シグナル伝達系を介した血管新生を調節する2013
- Author(s)
  安藝翔，吉岡和晃，岡本安雄，多久和典子，多久和陽
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸国際会議場/神戸国際展示場/神戸ポートピアホテル（兵庫県神戸市）
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] Endothelial PI3K-C2a, a class II PI3K, has an essential role in angiogenesis and vascular barrier function.2013
- Author(s)
  Yoshioka K
- Organizer
  Gordon Research Conference Vascular CeU Biology
- Place of Presentation
  Four Points Sheraton / Holiday Inn Express (USA)
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] 蛍光イメージングが拓く見せる血管生物学2013
- Author(s)
  吉岡和晃
- Organizer
  第21回日本血管生物医学会学術集会オリンパス・コーヒーブレークセミナー
- Place of Presentation
  大阪
- Year and Date
  2013-09-26
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] クラスII 型PI3K-C2αはSARA のエンドソームへの動員を制御しTGFß1-Smad2/3シグナル伝達系を介した血管新生を調節する2013
- Author(s)
  安藝翔，吉岡和晃，岡本安雄，多久和典子，多久和陽
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸国際会議場/神戸国際展示場/神戸ポートピアホテル（兵庫県神戸市）
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Sphingosine-1-phosphate receptor-2 plays a protective role against anaphylactic shock through inhibiting eNOS.2013
- Author(s)
  Cui H, Okamoto Y, Yoshioka K., Takuwa N, TakuwaY.
- Organizer
  第90 回　日本生理学会大会
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function.2013
- Author(s)
  Yoshioka K
- Organizer
  Gordon Reseach Conference Vascular Cell Biology
- Place of Presentation
  our Points Sheraton / Holiday Inn Express（ＵＳＡ）
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] S1P受容体はeNOS-NO経路を抑制することによりアナフラキシーショックに対して抑制的に働く2013
- Author(s)
  岡本安雄、崔弘、吉岡和晃、多久和典子、多久和陽
- Organizer
  第21回日本血管生物医学会
- Place of Presentation
  千里阪急ホテル（大阪府豊中市）
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] ClassII PI3-kinase2013
- Author(s)
  Kuntal Biswas, Kazuaki Yoshioka, Yasuo Okamoto, Noriko Takuwa and Yoh Takuwa
- Organizer
  PI3K-C2alpha, mediates S1P-induced endothelial cell migration through endosomal Rac1 activation Gordon Reseach Conference Vascular Cell Biology
- Place of Presentation
  Four Points Sheraton / Holiday Inn Express Express Ventura, (U.S.A)
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] Essential role of class Iiα-isoform PI3 kinase C2α in sphingosine-1-phosphate (S1P)-induced endothelial cell migration.2013
- Author(s)
  Biswas K, Yoshioka K., Takuwa N, Okamoto Y, Takuwa Y.
- Organizer
  第90 回　日本生理学会大会
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Essential role of class Iiα-isoform PI3 kinase C2αin sphingosine-1-phosphate (S1P)-induced endothelial cell migration2013
- Author(s)
  Biswas K, Yoshioka K ., Takuwa N, Okamoto Y, Takuwa Y
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] クラスIIa型PI3キナーゼC2αによる血管新生・バリア機能調節メカニズム2013
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和陽
- Organizer
  第21回日本血管生物医学会学術集会シンポジウム「血管機能を制御するシグナリング機構」
- Place of Presentation
  大阪
- Year and Date
  2013-09-27
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] クラスII型PI3キナーゼC2αはメンブレン・トラフィック調節を介する血管形成及び恒常性維持に必須である2013
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和陽
- Organizer
  第90回日本生理学会大会シンポジウム「細胞膜と細胞内膜における脂質制御とその生理機能」
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] クラスII型PI3キナーゼC2αはメンブレン・トラフィッキング調節を介する血管形成及び恒常性維持に必須である2013
- Author(s)
  吉岡和晃
- Organizer
  第90回日本生理学会
- Place of Presentation
  タワーホール船堀（東京都）
- Invited
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] Class II PI3K-C2α is essential for vascular barrier integrity.2013
- Author(s)
  Yoshioka, K., Yoshida, K., Okamoto, Y., Takuwa N. and Takuwa Y.
- Organizer
  JST-CREST International Symposium “Frontiers in Immunology and Inflammation: From Molecules and Inflammation.
- Place of Presentation
  一橋記念講堂（東京）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] S1P受容体はeNOS-NO経路を抑制することによりアナフラキシーショックに対して抑制的に働く2013
- Author(s)
  岡本安雄、崔弘、吉岡和晃、多久和典子、多久和陽
- Organizer
  第21回日本血管生物医学会
- Place of Presentation
  千里阪急ホテル（大阪府豊中市）
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Endothelial class II PI3K-C2α has an essential role in vascular formation and barrier function2013
- Author(s)
  Yoshioka, K., Yoshida, K., Okamoto, Y., Takuwa N. and Takuwa Y.
- Organizer
  Gordon Research Conference on Vascular Cell Biology
- Place of Presentation
  Four Points Sheraton/Holiday Inn Express, LA, USA
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Sphingosine- 1- phosphate receptor- 2 plays a protective role against anaphylactic shock through inhibiting eNOS2013
- Author(s)
  Cui H, Okamoto Y, Yoshioka K ., Takuwa N, Takuwa Y
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] クラスII型PI3キナーゼC2αはメンブレン・トラフィッキング調節を介する血管形成及び恒常性維持に必須である2013
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和陽
- Organizer
  第90回日本生理学会
- Place of Presentation
  タワーホール船堀(東京都)(招待講演)
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] Class II PI3 kinase, PI3K-C2α, mediates S1P-induced endothelial cell migration through endosomal Rac1 activation.2013
- Author(s)
  Biswas K, Yoshioka, K., Yoshida, K., Okamoto, Y., Takuwa N. and Takuwa Y.
- Organizer
  Gordon Research Conference on Vascular Cell Biology
- Place of Presentation
  Four Points Sheraton/Holiday Inn Express, LA, USA
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] S1P2は内皮型一酸化窒素合成酵素を抑制することによりアナフラキシーショックに対して防御的に働く2013
- Author(s)
  岡本　安雄　崔　弘　吉岡　和晃　多久和　典子　多久和　陽
- Organizer
  第55回日本脂質生化学会
- Place of Presentation
  ホテル松島大観荘(宮城県宮城郡)
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] TGFβ1-Smad2/3シグナル伝達系を介した血管新生調節におけるクラスIIαPI3キナーゼPI3K-C2αの機能的役割2013
- Author(s)
  安藝　翔、吉岡　和晃、多久和　典子、岡本　安雄、多久和　陽
- Organizer
  第21回日本血管生物医学会
- Place of Presentation
  千里阪急ホテル（大阪府豊中市）
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] クラスIIα型PI3キナーゼ-C2αによる血管新生・バリア機能調節メカニズム2013
- Author(s)
  吉岡　和晃、多久和　典子、岡本　安雄、多久和　陽
- Organizer
  第21回日本血管生物医学会シンポジウム「血管機能を抑制するシグナリング機構」
- Place of Presentation
  千里阪急ホテル（大阪府豊中市）
- Invited
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] クラスIIα型PI3キナーゼ-C2αによる血管新生・バリア機能調節メカニズム2013
- Author(s)
  吉岡　和晃、多久和　典子、岡本　安雄、多久和　陽
- Organizer
  第21回日本血管生物医学会　シンポジウム「血管機能を抑制するシグナリング機構」
- Place of Presentation
  千里阪急ホテル（大阪府豊中市）
- Invited
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] S1P2受容体はeNOS-NO経路を抑制することによりアナフィラキシーショックに対して抑制的に働く2013
- Author(s)
  岡本安雄、崔弘、吉岡和晃、多久和典子、多久和陽
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2013-09-26
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] クラスIIα型PI3キナーゼC2αは血管形成に必須である2012
- Author(s)
  吉岡和晃、岡本安雄、多久和典子、多久和陽
- Organizer
  第54回日本脂質生化学会
- Place of Presentation
  九州大学医学部百年講堂(福岡県)
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] クラスII型PI3キナーゼC2αは血管形成・血管恒常性維持に必須である2012
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和陽
- Organizer
  第35回日本分子生物学会・ワークショップ「メンブレントラフィックと疾患」
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] クラスII 型PI3 キナーゼC2αは血管形成に必須である2012
- Author(s)
  吉岡和晃、岡本安雄、多久和　典子、多久和　陽
- Organizer
  第54回　日本脂質生化学会
- Place of Presentation
  九州大学医学部百年講堂（福岡）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation]2012
- Author(s)
  Biswas K, Yoshioka K ., Takuwa N, Okamoto Y, Takuwa Y
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] ラスII 型PI3キナーゼC2αはエンドソーム上でのRac1活性化を制御してスフィンゴシン-1-リン酸(S1P)による血管内皮細胞遊走・管腔形成を調節する2012
- Author(s)
  Kuntal Biswas, 吉岡和晃, 岡本安雄, 多久和典子, 多久和陽
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡(福岡県)
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] クラスII型PI3キナーゼC2αノックアウトマウスにおける血管障壁機能の異常2012
- Author(s)
  吉岡和晃
- Organizer
  第89回日本生理学会大会(招待講演)
- Place of Presentation
  長野県松本文化会館（長野県）
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] クラスII型PI3キナーゼC2αは血管形成・血管恒常性維持に必須である2012
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和　陽
- Organizer
  第35回　日本分子生物学会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡）
- Invited
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] クラスII ・型P13キナーゼC2・は血管形成に必須である2012
- Author(s)
  吉岡和晃
- Organizer
  第54回日本脂質生化学会
- Place of Presentation
  九州大学医学部百年講堂(福岡県)
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] クラスII型P13キナーゼC2aは血管新生・恒常性維持に必須である2012
- Author(s)
  吉岡和晃
- Organizer
  第59回中部生理学会
- Place of Presentation
  自然科学研究機構岡崎コンファレンスセンター(愛知県)
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] クラスII型PI3キナーゼC2αノックアウトマウスにおける血管障壁機能の異常2012
- Author(s)
  吉岡和晃、吉田耕太朗、崔弘、安藝翔、Kuntal Biswas,趙娟娟、多久和典子、岡本安雄、多久和陽
- Organizer
  89回日本生理学会大会
- Place of Presentation
  日長野県松本文化会館(長野)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] クラスII型PI3キナーゼC2αは血管新生・恒常性維持に必須である2012
- Author(s)
  吉岡和晃、吉田耕太朗、岡本安雄、多久和　典子、多久和　陽
- Organizer
  第59回　中部日本生理学会
- Place of Presentation
  岡崎カンファレンスセンター（愛知）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Class II P13 kinase C2α has a crucial role in vascular formation and barrier integrity2012
- Author(s)
  Kazuaki Yoshioka
- Organizer
  20回日本血管生物医学会
- Place of Presentation
  あわぎんホール(徳島県)
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Essential role of class IIa -isoform PI3 kinase C2αin sphingosine-1-phosphate (S1P)-induced endothelial cell migration2012
- Author(s)
  Biswas K, Yoshioka K ., Takuwa N, Okamoto Y, Takuwa Y
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] 血管内皮機能におけるクラスII型PI3キナーゼC2αの役割2012
- Author(s)
  吉岡和晃、岡本安雄、多久和典子、多久和陽
- Organizer
  第54回第2回Vividワークショップ
- Place of Presentation
  石川、加賀
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] スフィンゴシン-1-リン酸による血管内皮細胞遊走におけるクラスII型PI3キナーゼC2αの役割2012
- Author(s)
  Kuntal Biswas、吉岡和晃、多久和典子、岡本安雄、多久和陽
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  日長野県松本文化会館(長野)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] クラスII 型PI3 キナーゼC2αは血管新生・恒常性維持に必須である2012
- Author(s)
  吉岡和晃
- Organizer
  第59回中部生理学会
- Place of Presentation
  自然科学研究機構岡崎コンファレンスセンター（愛知県）
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] クラスII型P13キナーゼC2αは血管形成・血管恒常性維持に必須である2012
- Author(s)
  吉岡和晃
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡(福岡県)(招待講演)
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Class II PI3K-C2α is essential for vascular barrier integrity2012
- Author(s)
  Kazuaki Yoshioka
- Organizer
  International Endotoxin and Innate Immunity Society Meeting 2012
- Place of Presentation
  学術総合センター（東京都）
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] クラスII型PI3キナーゼC2αノックアウトマウスにおける血管障壁機能の異常2012
- Author(s)
  吉岡和晃、吉田耕太朗、崔弘、安藝翔、Kuntal Biswas, 趙娟娟、多久和典子、岡本安雄、多久和　陽
- Organizer
  第89回日本生理学会大会(招待講演)
- Place of Presentation
  長野県松本文化会館（長野県）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] クラスII型PI3キナーゼC2αノックアウトマウスにおける血管障壁機能の異常2012
- Author(s)
  吉岡和晃
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  長野県松本文化会館(長野県)(招待講演)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] クラスII型PI3キナーゼC2αは血管新生・恒常性維持に必須である2012
- Author(s)
  吉岡和晃、吉田耕太朗、岡本安雄、多久和典子、多久和陽
- Organizer
  第59回中部日本生理学会
- Place of Presentation
  岡崎
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Class II PI3K-C2α is essential for vascular barrier integrity.2012
- Author(s)
  Yoshioka, K., Yoshida, K., Okamoto, Y., Takuwa N. and Takuwa Y.
- Organizer
  IEIIS2012 Homeostatic Inflammation Symposium.
- Place of Presentation
  一橋記念講堂（東京）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] スフィンゴシン－1－リン酸による血管内皮細胞遊走におけるクラスII 型PI3 キナーゼC2α の役割2012
- Author(s)
  Kuntal Biswas、吉岡和晃、多久和典子、岡本安雄、多久和　陽
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  長野県松本文化会館（長野県）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] 機能性脂質とその代謝酵素による血管恒常性維持メカニズム2012
- Author(s)
  吉岡和晃
- Organizer
  シンポジウム「食」による生活習慣病予防医学の展開
- Place of Presentation
  金沢
- Year and Date
  2012-12-06
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] クラスIIα型PI3キナーゼC2αは血管形成に必須である2012
- Author(s)
  吉岡和晃
- Organizer
  第54回日本脂質生化学会
- Place of Presentation
  九州大学医学部百年講堂(福岡県）
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] クラスII型PI3キナーゼC2αは血管形成・血管恒常性維持に必須である2012
- Author(s)
  吉岡和晃, 多久和典子, 岡本安雄, 多久和陽
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡(福岡県)(招待講演)
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] クラスII型PI3キナーゼC2αは血管形成に必須である2012
- Author(s)
  吉岡和晃、岡本安雄、多久和典子、多久和陽
- Organizer
  第54回日本脂質生化学会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Class II PI3K"C2&alphai is essential for vascular barrier integrity2012
- Author(s)
  Kazuaki Yoshioka
- Organizer
  International Endotoxin and Innate Immunity Society Meeting 2012
- Place of Presentation
  学術総合センター(東京都)
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Class II PI3 kinase C2α has a crucial role in vascular formation and barrier integrity2012
- Author(s)
  Kazuaki Yoshioka
- Organizer
  第20回日本血管生物医学会
- Place of Presentation
  あわぎんホール（徳島県）
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] クラスII型PI3キナーゼC2αは血管形成・血管恒常性維持に必須である2012
- Author(s)
  吉岡和晃
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡県）
- Invited
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] Endothelial class II PI3K-Ca2a has an essential role for physiological and pathological angiogenesis2011
- Author(s)
  Kazuaki Yoshioka
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県立音楽堂(石川県)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] クラスII型PI3キナーゼC2αは血管新生と障壁機能に必須である2011
- Author(s)
  吉岡和晃
- Organizer
  第88回日本生理学会
- Place of Presentation
  パシフィコ横浜・会議センター誌上開催
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] Role of Lysophospholipid Mediator Sphingosine-1-phosphate in Cardiac Fibrosis 1st Meeting of Asian-Pacific Federation of Inflammation and Regeneration2011
- Author(s)
  Yoh Takuwa, Noriko Takuwa, Seiichiro Ohkura, Shin-ichiro Takashima, Soichiro Usui2, Shuichi Kaneko, Yasuo Okamoto, Kazuaki Yoshioka
- Organizer
  第32回日本日本炎症・再生医学会
- Place of Presentation
  国立京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] Role of Lysophospholipid Mediator Sphingosine-1-phosphate in Cardiac Fibrosis2011
- Author(s)
  Yoh Takuwa, Noriko Takuwa, Seiichiro Ohkura, Shin-ichiro Takashima, Soichiro Usui2, Shuichi Kaneko, Yasuo Okamoto, Kazuaki Yoshioka
- Organizer
  1st Meeting of Asian-Pacific Federation of Inflammation and Regeneration and 第32回日本日本炎症・再生医学会　シンポジウム(招待講演)
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] クラスII型PI3キナーゼC2αは血管新生と障壁機能に必須である2011
- Author(s)
  吉岡和晃、吉田耕太郎、崔弘、安藝翔、Kuntal Biswasl、多久和典子、岡本安雄、多久和陽
- Organizer
  第88回日本生理学会大会
- Place of Presentation
  パシフィコ、横浜(神奈川、誌上開催)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Endothelial class II PI3K-Ca2a has an essential role for physiological and pathological angiogenesis.2011
- Author(s)
  Kazuaki Yoshioka
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県立音楽堂（石川県）
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] Endothelial class II PI3K-Ca2a has an essential role for physiological and pathological angiogenesis.2011
- Author(s)
  Kazuaki Yoshioka, Kotaro Yoshida, Hong Cui, Xun Qi, Tomohiko Wakayama, Noriko Takuwa, Yasuo Okamoto, Kazushi Sugihara, Sho Aki, Kuntal Biswas, Masahide Asano, Yoh Takuwa.
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県立音楽堂（石川県）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Function role of sphingosine-1-phosphate signaling in angiogenesis.2011
- Author(s)
  Yasuo Okamoto, Xun Qi, Wa Du, Noriko Takuwa, kazuaki Yoshioka, Yoh Takuwa
- Organizer
  The 1st Asia-Pacific Vascular Biology Meeting/第19回日本血管生物医学会学術集会(招待講演)
- Place of Presentation
  東京ステーションコンファレンス（東京都）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Proatherogenic role of sphingosine-1-phosphate receptor-22011
- Author(s)
  Yoh Takuwa Fei Wang Yasuo Okamoto Kazuaki Yoshioka Noriko Takuwa
- Organizer
  2011 FASEB Summer Research Conference: Lysophospholipid Mediators in Health and Disease
- Place of Presentation
  Il Ciocco Hotel & Resort（イタリア）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Endothelial class II PI3K-Ca2a has an essential role for physiological and pathological angiogenesis2011
- Author(s)
  Kazuaki Yoshioka, Kotaro Yoshida, Hong Cui, Xun Qi, Tomohiko Wakayama, Noriko Takuwa, Yasuo Okamoto, Kazushi Sugihara, Sho Aki, Kuntal Biswas, Masahide Asano, Yoh Takuwa
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県立音楽堂(金沢)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] eletion of sphingosine -1-receptor-2(S1PR2) inhibits proinflammatory activities of macrophages and atherosclerosis in apoE-deficient mice2011
- Author(s)
  Wang Fei, Yasuo Okamoto, Isao Inoki, Kazuaki Yoshioka, Xun Qi, Hong Cui Biswas Kuntal, Sho Aki, Dandar Erdembileg, Noriko Takuwa, Yasuhiko Yamamoto, Masahide Asano, Yoh Takuwa
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県立音楽堂（石川県）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] S1P2受容体遺伝子の破壊はapoE欠損マウスにおける粥状動脈硬化を抑制する2011
- Author(s)
  岡本安雄，王　飛，居軒　功，吉岡和晃，多久和典子，多久和　陽
- Organizer
  第58回中部日本生理学会
- Place of Presentation
  福井県県民ホール（福井県）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Endothelial class II PI3K-Ca2a has an essential role for physiological and pathological angiogenesis2011
- Author(s)
  Kazuaki Yoshioka, Kotaro Yoshida, Hong Cui, Xun Qi, Tomohiko Wakayama, Noriko Takuwa, Yasuo Okamoto, Kazushi Sugihara, Sho Aki, Kuntal Biswas, Masahide Asano, Yo h Takuwa
- Organizer
  日本分子生物学会第11回春季シンポジウムポスタ
- Place of Presentation
  石川県立音楽堂(石川県)
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] Deletion of sphingosine-1-phosphate receptor-2 inhibits macrophages proinflammatory activities and atherosclerosis in apoE-deficient mice.2011
- Author(s)
  Yasuo Okamoto Fei Wang Isao Inoki Kazuaki Yoshioka Noriko Takuwa Yoh Takuwa
- Organizer
  2011 FASEB Summer Research Conference: Lysophospholipid Mediators in Health and Disease
- Place of Presentation
  Il Ciocco Hotel & Resort（イタリア）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Function role of sphingosine-1-phosphate signaling in angiogenesis2011
- Author(s)
  Yasuo Okamoto, Xun Qi, Wa Du, Noriko Takuwa, Kazuaki Yoshioka, Yoh Takuwa
- Organizer
  第19回日本血管生物医学会学術集会
- Place of Presentation
  東京ステーションコンファレンス(東京)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] ポリ乳酸―グリコール酸共重合体を基材としたスフィンゴシン-1-リン酸徐放微粒子製剤による持続性放出はマウス虚血肢においてAkt/ERK-eNOSを介して血管新生および血管成熟を促進し血流を回復させる2011
- Author(s)
  戚　勛、岡本　安雄、吉岡　和晃、王　飛、崔　弘、Biswas Kuntal、安藝　翔、Dandar Erdembileg、多久和　典子、多久和　陽
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県立音楽堂（石川県）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Sphingosine-1-phosphate receptor-2 facilitates atherosclerosis in apoE-deficient maide.2011
- Author(s)
  Fei Wang, Yasuo Okamoto, Isao Inoki, Kazuaki Yoshioka, Noriko Takuwa, Yoh Takuwa
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] クラスII型PI3キナーゼC2αは血管新生と障壁機能に必須である2011
- Author(s)
  吉岡和晃、吉田耕太郎、崔弘、安藝翔、Kuntal Biswas、多久和典子、岡本安雄、多久和陽
- Organizer
  第88回日本生理学会ポスター
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] Endothelial class II PI3K-C2αhas an essential role for physiological and pathological angiogenesis2011
- Author(s)
  Yoshioka K ., Kotaro Yoshida, Hong Cui, Xun Qi, Tomohiko Wakayama, Noriko Takuwa, Yasuo Okamoto, Kazushi Sugihara, Sho Aki, Kuntal Biswas, Masahide Asano, Yoh Takuwa
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県立音楽堂(金沢)
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] ポリ乳酸-グリコール酸共重合体を基材としたスフィンゴシン-1-リン酸徐放微粒子製剤による持続性放出はマウス虚血肢においてAkt/ERK-eNOSを介して血管新生および血管成熟を促進し血流を回復させる2011
- Author(s)
  戚〓、岡本安雄、吉岡和晃、王飛、崔弘、Biswas Kuntal、安藝翔、Dandar Erdembileg、多久和典子、多久和陽
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県立音楽堂(金沢)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] ポリ乳酸―グリコール酸共重合体を基材としたスフィンゴシン-1-リン酸徐放微粒子製剤による持続性放出はマウス虚血肢においてAkt/ERK-eNOSを介して血管新生および血管成熟を促進し血流を回復させる2011
- Author(s)
  戚勛、岡本安雄、吉岡和晃、崔弘、Biswas Kuntal、安藝翔、Dandar Erdembileg、多久和典子、多久和陽
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県立音楽堂(金沢)
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Role of Lysophospho lipid Mediator Sphingosine-1-phosphate in Cardiac Fibrosis2011
- Author(s)
  Yoh Takuwa, Noriko Takuwa, Seiichiro Ohkura, Shin-ichiro Takashima, Soichiro Usui, Shuichi Kaneko, Yasuo Okamoto, Yoshioka K
- Organizer
  第32回日本日本炎症・再生医学会シンポジウム
- Place of Presentation
  京都国際会館・京都
- Invited
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Delection of sphingosine-1-phosphate reseptor-2 inhibits proinflammatory activities of macrophages and atherosclerosis in apoE-deficient mice.2011
- Author(s)
  Wang Fei, Yasuo Okamoto, Isao Inoki, Kazuaki Yoshioka, Noriko Takuwa, Ryunosuke Ohkawa, Yutaka Yatomi, Makoto Kinoshita, Yoh Takuwa.
- Organizer
  第53回日本脂質生化学会
- Place of Presentation
  ホテル東京ガーデンパレス（東京都）
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] 健康な血管維持に貢献する新規モデルマウスの開発2011
- Author(s)
  吉岡和晃、多久和陽
- Organizer
  第2回金沢大学若手研究者シーズ発表会
- Place of Presentation
  金沢
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Class II PI3K-C2α regulates angiogenesis via TGFβ1-Smad2/3 signaling in endothelial cell.2010
- Author(s)
  Aki S, Yoshioka K, Okamoto Y, Takuwa Y
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール(岩手)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] クラスII型PI3キナーゼC2αの血管形成における生理的役割:コンディショナルKOマウスを用いた解析2010
- Author(s)
  吉岡和晃、吉田耕太朗、安藝翔、Kuntal Biswas、Wa Du、Xun Qi、Fei Wang、多久和典子、岡本安雄、多久和陽
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  日盛岡市民文化ホールいわて県民情報交流センター(岩手)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] A novel mechanism of Ca^<2+> regulation of vascular smooth muscle contraction involving classll PI3 kinase-dependent inhibition of myosin light chain phosphatase2010
- Author(s)
  Takuwa, Y., Yoshioka.K., Okamoto, Y., Takuwa N
- Organizer
  1^<st> International Symposium of Biorheology
- Place of Presentation
  Wako, Saitama, Japan(招待講演)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] シンポジウム(リゾ脂質受容体研究の新展開)S1P2受容体によるがん血管新生抑制とそのメカニズム2010
- Author(s)
  多久和典子、杜娃、吉岡和晃、岡本安雄、多久和陽
- Organizer
  第52回日本脂質生化学会
- Place of Presentation
  伊香保会館(群馬)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Sphingosine-1-phosphate receptor-2 deletion inhibits macrophage pro-inflammatory activities and atherosclerosis in mice2010
- Author(s)
  王飛、岡本安雄、居軒功、吉岡和晃、多久和典子、多久和陽
- Organizer
  第18回日本血管生物医学会
- Place of Presentation
  大阪スカイビル(大阪)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] リゾリン脂質メディエータ-スフィンゴシン-1-リン酸受容体(S1P_2)のシグナル伝達と血管新生制御作用2010
- Author(s)
  多久和陽、岡本安雄、多久和典子、杜娃、戚〓、吉岡和晃
- Organizer
  第7回GPCR研究会
- Place of Presentation
  日本科学未来館(東京都)(招待講演)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Development of Cardiac Fibrosis in Sphingosine Kinase 1 Transgenic Mice through an S1P3 Receptor-mediated Reactive Oxygen Species-dependent Process2010
- Author(s)
  Noriko Takuwa, Seiichiro Ohkura, Shinichiro Takashima, Keisuke Ohtani, Yasuo Okamoto, Soichiro Usui, Kazuaki Yoshioka, Masayuki Takamura, Shuichi Kaneko, Yoh Takuwa
- Organizer
  第74回日本循環器学会総会
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] シンポジウム「脂質メディエーターと動脈硬化」"Role of sphingosine-1-phosphatere ceptor-2 in atherosclerosis"2010
- Author(s)
  多久和陽、王飛、岡本安雄、吉岡和晃、多久和典子
- Organizer
  第42回日本動脈硬化学会
- Place of Presentation
  長良川国際会議場(岐阜県)(招待講演)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] シンポジウム(リゾ脂質受容体研究の新展開)S1P2受容体によるがん血管新生抑制とそのメカニズム2010
- Author(s)
  多久和典子、杜娃、吉岡和晃、岡本安雄、多久和陽
- Organizer
  第52回日本脂質生化学会
- Place of Presentation
  森秋旅館(群馬県)(招待講演)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] クラスIIα型PI3キナーゼC2αは血管新生及びバリアー機能に必須である2010
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和陽
- Organizer
  第18回日本血管生物医学会
- Place of Presentation
  大阪スカイビル(大阪)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] スフィンゴ脂質メディエーター情報伝達系(G蛋白共役型受容体S1P2)を標的としたがん治療の新戦略2010
- Author(s)
  杜娃、多久和典子、吉岡和晃、岡本安雄、多久和陽
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] クラスIIα型PI3キナーゼC2αは血管新生及びバリアー機能に必須である第18回血管生物医学会2010
- Author(s)
  吉岡和晃
- Organizer
  第18回血管生物医学会
- Place of Presentation
  梅田スカイビル(大阪)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] S1P2受容体によるがん血管新生抑制とそのメカニズム2010
- Author(s)
  多久和典子、杜娃、吉岡和晃、岡本安雄、多久和陽
- Organizer
  日本脂質生化学会
- Place of Presentation
  森秋旅館(群馬伊香保)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] クラスIIα型PI3キナーゼC2αは血管新生及びバリアー機能に必須である2010
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和陽
- Organizer
  第18回日本血管生物医学会
- Place of Presentation
  梅田スカイビル(大阪)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Signaling of vascular smooth muscle contraction2010
- Author(s)
  Yoh Takuwa, Yasuo Okamoto, Kazuaki Yoshioka, Noriko Takuwa.
- Organizer
  1st International Conference on Biorheology
- Place of Presentation
  和光市
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] クラスIIα型PI3キナーゼC2αは血管新生及びバリアー機能に必須である2010
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和陽
- Organizer
  第18回血管生物医学会
- Place of Presentation
  梅田スカイビル(大阪)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] Physiological role of class II PI3K-C2α for vascular formation : conditional knockout mouse study2010
- Author(s)
  Yoshioka K, Yoshida K, AkiS, Biswas K, Du W, Qi X, Wang F, Takuwa N, Okamoto Y, Takuwa Y.
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール(岩手盛岡市)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] The role of vascular Ca^<2+>-PI3KC2α-Rho axis in hypertension of spontaneously hypertensive ratsシンポジウム(血管トーヌス調節の分子機構とその異常)2010
- Author(s)
  Okamoto Y, Seok YM, Azam MA, Sato A, Yoshioka K, Wang F, Cui H, Takuwa N, Takuwa
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール(岩手)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Role of sphingosine-1-phosphate receptor-2 in atherosclerosis2010
- Author(s)
  多久和陽、王飛、岡本安雄、吉岡和晃、多久和典子
- Organizer
  第42回日本動脈硬化学会(シンポジウム「脂質メディエーターと動脈硬化」)
- Place of Presentation
  長良川国際会議場(岐阜)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Sphingosine-1-phosphate receptor-2 inhibits tumor angiogenesis and tumor growth in vivo in mice Keystone Symposia Bioactive Lipids2010
- Author(s)
  Wa Du, Noriko Takuwa, Kazuaki Yoshioka, Yasuo Okamoto, and Yoh Takuwa
- Organizer
  Biochemistry and Diseases
- Place of Presentation
  ウエステン都ホテル京都(京都)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] スフィンゴ脂質メディエータ-情報伝達系(G蛋白共役型受容体S1P2)を標的としたがん治療の新戦略2010
- Author(s)
  杜娃、多久和典子、吉岡和晃、岡本安雄、多久和陽
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Physiological role of class II PI3K-C2α for vascular formation : conditional knockout mouse study2010
- Author(s)
  Yoshioka K, Yoshida K, Aki S, Biswas K, Du W, Qi X, Wang F, Takuwa N, Okamoto Y, Takuwa Y
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール(岩手)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] A novel mechanism of Ca^<2+> regulation of vascular smooth muscle contraction involving classII PI3 kinase-dependent inhibition of myosin light chain phosphatase2010
- Author(s)
  多久和陽, 吉岡和晃, 岡本安雄, 多久和典子
- Organizer
  1^<st> International Symposium of Biorheology
- Place of Presentation
  理化学研究所(埼玉)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Class II PI3K-C2α regulates angiogenesis via TGFβ1-Smad2/3 signsling in endothelial cell2010
- Author(s)
  AkiS, Yoshioka K, Okamoto Y, Takuwa Y
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  岩盛岡市民文化ホール(岩手県)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Development of cardiac fibrosis in sphingosine kinase 1 transgenic mice through an S1P3 receptor-mediated, reactivec oxygen species-dependent process2010
- Author(s)
  Takuwa N, Ohkura S, Takashima S, Ohtani K, Okamoto Y, Usui S, Yoshioka K, Takamura M, Kaneko S, Takuwa Y
- Organizer
  第74回日本循環器学会
- Place of Presentation
  京都国際会議場(京都)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] リゾリン脂質メディエータースフィンゴシン-1-リン酸受容体(S1P2)のシグナル伝達と血管新生制御作用2010
- Author(s)
  多久和陽、岡本安雄、多久和典子、杜娃、戚〓、吉岡和晃
- Organizer
  第7回GPCR研究会
- Place of Presentation
  日本科学未来館(東京)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] The role of vascular Ca^<2+>-PI3KC2α-Rho axis in hypertension of spontaneously hypertensiver ats シンポジウム(血管トーヌス調節の分子機構とその異常)2010
- Author(s)
  Okamoto Y, SeokY M, Azam MA, Sato A, Yoshioka K, Wang F, Cui H, Takuwa N, Takuwa
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  岩盛岡市民文化ホール(岩手県)(招待講演)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Bimodal actions of the cardiac sphingosine-1-phosphate signaling revealed in sphingosine kinase 1transgenic mice : S1P3-mediated, Rho- and active oxygen-dependent, chronic progression ofspontaneous cardiac remodeling and cardioprotection against acutely imposed ischemia reperfusion injury in sphingosine kinase 1 transgenic mice.2010
- Author(s)
  Takuwa N, Ohkura S, Takashima S, Ohtani K, Usui S, Okamoto Y, Wang F, Du W, Yoshioka K, Takuwa Y
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Sphingosine-1-phosphate receptor-2 deletion inhibits macrophage pro-inflammatory activities and atherosclerosis in mice2010
- Author(s)
  王飛、岡本安雄、居軒功、吉岡和晃、多久和典子、多久和陽
- Organizer
  第18回日本血管生物医学会
- Place of Presentation
  梅田スカイビル(大阪府)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] 腫瘍血管新生におけるスフィンゴシンー1-リン酸受容体S1P2の役割2009
- Author(s)
  Wa Du,多久和典子,吉岡和晃,岡本安雄, Xun Qi, Fei Wang, Hong Cui, Kuntal Biswas,杉原一司,浅野雅秀,多久和陽
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] INVOLVEMENT OF THE Ca2+-PI3K-C2ALPHARHO-MLC PHOSPHATASE PATHWAY IN HYPERTENSION2009
- Author(s)
  Yasuo Okamoto, Mohammed Ali Azam, Kazuaki Yoshioka, Yoh Takuwa
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] マウス後肢虚血モデルにおける徐放化S1P製剤を用いた血管新生療法2009
- Author(s)
  戚〓、岡本安雄、村川智美、王飛、尾山治、吉岡和晃、杜娃、多久和典子、多久和陽
- Organizer
  第17回日本血管生物医学会
- Place of Presentation
  東京大学(東京)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] The pathophysiological roles of phosphoinositide 3-kinase (PI3K) classII α isoform, a Ca^<2+>-dependent regulator of Rho in vascular smooth muscle, in vascular contraction and blood pressure regulation2009
- Author(s)
  Takuwa Y., Yoshioka K., Okamoto Y., Azam MA., Seok YM., Asano M., Takuwa N.
- Organizer
  IUPS2009 Symposium
- Place of Presentation
  名古屋市立大学病院(愛知県)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Atsusi Sato Noriko Takuwa The pathophysiolosical roles of phosphoinositide 3-kinase(PI3K) class II a-isoform, a Ca2+-dependent regulator of Rho in vascular smooth blood pressure regulation Post-Genomic Advances in the Physiology of Smooth2009
- Author(s)
  Yoh Takuwa, Kazuaki Yoshioka, Yasuo Okamoto Mohammed Ali Azam, Young Mi Seok
- Organizer
  Muscle Satellite Symposium of IUPS 2009
- Place of Presentation
  名古屋市立大学病院(名古屋)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] 心筋リモデリングにおけるスフィンゴシン-1-リン酸情報伝達系の病態生理学的役割-スフィンゴシンキナーゼ1トランスジェニックマウスを用いた検討-2009
- Author(s)
  多久和典子,大倉誓一郎,高島伸一郎,大谷啓輔,薄井荘一郎,岡本安雄,王飛,杜娃,吉岡和晃,多久和陽
- Organizer
  第56回中部日本生理学会
- Place of Presentation
  石川県立音楽堂(金沢)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] G_<12/13> and G_q coordinately mediates S1P_2-induced inhibition of Rac and migration in vascular smooth muscle in Rho-dependent mannar2009
- Author(s)
  Takashima S., Sugimoto N., Takuwa N., Okamoto Y., Yoshioka K., Takamura M., Kaneko S., Takuwa Y.
- Organizer
  第73回日本循環器学会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Role of phosphoinositide 3-kinase (PI3K) class isoform, a novel Ca^<2+>-dependent regulator of Rho in vascular smooth muscle, in hypertension2009
- Author(s)
  Takuwa Y., Yoshioka K., Okamoto Y., Azam, M.A., Maeda M., Takuwa N.
- Organizer
  The 6^<th> Korea-Japan Joint Symposium on Vascular Biology
- Place of Presentation
  石川県立音楽堂(石川県)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] 血管内皮細胞のTGFb1-Smadシグナル伝達系におけるクラスIIa型PI3キナーゼC2aの役割2009
- Author(s)
  安藝翔,吉岡和晃,岡本安雄,多久和陽
- Organizer
  第56回中部日本生理学会
- Place of Presentation
  石川県立音楽堂(金沢)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] RHOMLC PHOSPHATASE PATHWAY IN HYPERTENSION2009
- Author(s)
  Yasuo Okamoto, Mohammed Ali Azam, Kazuaki Yoshioka, Yoh Takuwa
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] マウス虚血後血管新生モデルにおける除放化S1P製剤を用いた血管新生療法2009
- Author(s)
  戚〓、岡本安雄、村川智美、王飛、尾山治、杉本直俊、吉岡和晃、杜娃、多久和典子、多久和陽
- Organizer
  第17回日本血管生物医学会
- Place of Presentation
  東大・安田講堂(東京)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Masahide Asano and Yoh Takuwa HOST CELL S1P2 RECEPTOR NEGATIVELY REGULATES TUMOR GROWTH AND ANGIOGENESIS IN VIVO International Conference on Phospholipase A2 and Lipid Mediators2009
- Author(s)
  Wa Du, Noriko Takuwa, Kazuaki Yoshioka, Yasuo Okamoto
- Place of Presentation
  National Center of Sciences(東京)
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] HOST CELL S1P2 RECEPTOR NEGATIVELY REGULATES TUMOR GROWTH AND ANGIOGENESIS IN VIVO2009
- Author(s)
  Wa Du, Noriko Takuwa, Kazuaki Yoshioka, Yasuo Okamoto, Masahide Asano and Yoh Takuwa.
- Organizer
  International Conference on Phospholipase A2 and Lipid Mediators
- Place of Presentation
  学術総合センター(東京)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] リゾリン脂質メディエータースフィンゴシン-1-リン酸(S1P)はS1P2受容体を介して腫瘍血管新生・成熟を抑制する2008
- Author(s)
  杜娃、多久和典子、吉岡和晃、岡本安雄、多久和陽
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] 除放化S1P製剤による虚血後血管新生の促進2008
- Author(s)
  戚〓、村川智美、尾山治、杉本直俊、王飛、杜娃、吉岡和晃、岡本安雄、多久和典子、水岸貴代美、多久和陽
- Organizer
  第50回日本脂質生化学会
- Place of Presentation
  徳島県郷土文化会館(徳島)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Sphingosine-1-phosphate signaling in tumor biology THE U.S. -JAPAN COOPERATIVE CANCER RESEARCH PROGRAM WORKSHOP2008
- Author(s)
  Yoh Takuwa, Wa Du, Noriko Takuwa, Kazuaki Yoshioka, Yasuo Okamoto
- Place of Presentation
  (平安会館)京都
- Year and Date
  2008-03-20
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] S1P2 is an angiogenesis-suppressive receptor2008
- Author(s)
  Takuwa Y., Du W., Qi X., Okamoto Y., Takuwa N., Asano M., Yoshioka K.
- Organizer
  4^<th> International Conference on PhospholipaseA2 and Lipid Mediators
- Place of Presentation
  学士会館(東京都)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] Sphingosine-1-phosphate receptor-2(S1P2R) negatively regulates tumor angiogenesis, vascular maturation and integrity in vivo.2008
- Author(s)
  Du W, Takuwa N, Yoshioka K, Wang F, Nagakura C, Kaneko E, Takuwa Y
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  京王プラザホテル(東京)
- Data Source
  KAKENHI-PROJECT-20590207
[Presentation] クラスIIα型PI3キナーゼC2αによる血管新生・バリア機能調節メカニズム
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和　陽
- Organizer
  第21回　日本血管生物医学会学術集会・シンポジウム「血管機能を制御するシグナリング機構」
- Place of Presentation
  千里阪急ホテル（大阪府大阪市）
- Invited
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] スフィンゴシン-１-リン酸２型受容体は内皮型一酸化窒素合成酵素を抑制し、アナフィラキシーショックを防御する
- Author(s)
  岡本安雄、崔　弘、吉岡和晃、多久和典子、趙　娟娟、多久和　陽
- Organizer
  第９１回　日本生理学会大会・シンポジウム「血流分布不均衡性ショックと血圧調節破綻のメカニズム」
- Place of Presentation
  鹿児島大学（鹿児島県鹿児島市）
- Invited
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Distinct role of S1P2 in the functional regulation of vascular endothelium and smooth muscle
- Author(s)
  Yoh Takuwa, Yasuo Okamoto, Kazuaki Yoshioka, Noriko Takuwa
- Organizer
  The 18th International Vascular Biology Meeting 2014 (IVBM 2014)
- Place of Presentation
  みやこめっせ（京都府京都市）
- Year and Date
  2014-04-14 – 2014-04-17
- Invited
- Data Source
  KAKENHI-PROJECT-26460292
[Presentation] Distinct role of S1P2 in the functional regulation of vascular endothelium and smooth muscle
- Author(s)
  Yoh Takuwa, Yasuo Okamoto, Kazuaki Yoshioka, Noriko Takuwa
- Organizer
  The 18th International Vascular Biology Meeting 2014 (IVBM 2014)
- Place of Presentation
  みやこめっせ
- Year and Date
  2014-04-14 – 2014-04-17
- Invited
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] クラスIIα型PI3K-C2αはALK5 内在化及び足場タンパクSARA のエンドソームへの動員を制御しTGF1-Smad2/3 を介した血管新生を調節する
- Author(s)
  安藝翔、吉岡和晃、岡本安雄、多久和典子、多久和陽
- Organizer
  第56回日本脂質生化学会
- Place of Presentation
  近畿大学東大阪キャンパス（大阪府東大阪市）
- Year and Date
  2014-06-06 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-26460292
[Presentation] 機能性脂質とその代謝酵素による血管恒常性維持メカニズム
- Author(s)
  吉岡和晃
- Organizer
  シンポジウム「食」による生活習慣病予防医学の展開
- Place of Presentation
  KKRホテル金沢（石川）
- Invited
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Distinct role of S1P2 in the functional regulation of vascular endothelium and smooth muscle
- Author(s)
  Yoh Takuwa, Yasuo Okamoto, Kazuaki Yoshioka, Noriko Takuwa
- Organizer
  The 18th International Vascular Biology Meeting 2014 (IVBM 2014)
- Place of Presentation
  みやこめっせ（京都府・京都市）
- Year and Date
  2014-04-14 – 2014-04-17
- Invited
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Sphingosine-1-phosphate receptor-2 (S1P2) negatively regulates eNOS and protects against acute vascular barrier disruption
- Author(s)
  Yasuo Okamoto, Cui Hong, Kazuaki Yoshioka, Noriko Takuwa, Toshishige Shibamoto, Yoh Takuwa
- Organizer
  The 18th International Vascular Biology Meeting 2014 (IVBM 2014)
- Place of Presentation
  みやこめっせ
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] クラスII型PI3K-C2αは細胞内メンブレン・トラフィック調節を介して血管バリア機能を制御する
- Author(s)
  吉岡和晃吉田耕太郎、多久和典子、岡本安雄、多久和　陽
- Organizer
  第９１回　日本生理学会大会・シンポジウム「心血管系の形態・機能研究の最前線」
- Place of Presentation
  鹿児島大学（鹿児島県鹿児島市）
- Invited
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Sphingosine-1-phosphate receptor-2 (S1P2) negatively regulates eNOS and protects against acute vascular barrier disruption
- Author(s)
  Yasuo Okamoto, Cui Hong, Kazuaki Yoshioka, Noriko Takuwa, Toshishige Shibamoto, Yoh Takuwa
- Organizer
  The 18th International Vascular Biology Meeting 2014 (IVBM 2014)
- Place of Presentation
  みやこめっせ（京都府・京都市）
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Sphingosine 1-phosphate receptor-2 plays a protective role against lipopolysaccharide (LPS)-induced acute lung injury
- Author(s)
  Yasuo Okamoto, Hong Cui, Kazuaki Yoshioka, Noriko Takuwa, Sho Aki, JuanJuan Zhao, Hoa Quynh Pham, Md. Azadul Kabir Sarker, Saori Koizumi, Yoh Takuwa
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場・展示場
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] Sphingosine 1-phosphate receptor-2 plays a protective role against lipopolysaccharide (LPS)-induced acute lung injury
- Author(s)
  Yasuo Okamoto, Hong Cui, Kazuaki Yoshioka, Noriko Takuwa, Sho Aki, JuanJuan Zhao, Hoa Quynh Pham, Md. Azadul Kabir Sarker, Saori Koizumi, Yoh Takuwa
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場・展示場（兵庫県・神戸市）
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] 蛍光イメージングが拓く見せる血管生物学
- Author(s)
  吉岡和晃
- Organizer
  第21回　日本血管生物医学会学術集会・オリンパス・コーヒーブレークセミナー
- Place of Presentation
  千里阪急ホテル（大阪府大阪市）
- Invited
- Data Source
  KAKENHI-PROJECT-23590257
[Presentation] Sphingosine 1-phosphate receptor-2 plays a protective role against lipopolysaccharide (LPS)-induced acute lung injury
- Author(s)
  Yasuo Okamoto, Hong Cui, Kazuaki Yoshioka, Noriko Takuwa, Sho Aki, JuanJuan Zhao, Hoa Quynh Pham, Md. Azadul Kabir Sarker, Saori Koizumi, Yoh Takuwa
- Organizer
  第92回　日本生理学会大会
- Place of Presentation
  神戸国際会議場・展示場（神戸市、兵庫県）
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-26460292
[Presentation] クラスIIα型PI3K-C2αはALK5 内在化及び足場タンパクSARA のエンドソームへの動員を制御しTGF-1-Smad2/3 を介した血管新生を調節する
- Author(s)
  安藝翔、吉岡和晃、岡本安雄、多久和典子、多久和陽
- Organizer
  第56回日本脂質生化学会
- Place of Presentation
  近畿大学東大阪キャンパス（大阪府・東大阪市）
- Year and Date
  2014-06-06 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Sphingosine-1-phosphate receptor-2 (S1P2) negatively regulates eNOS and protects against acute vascular barrier disruption
- Author(s)
  Yasuo Okamoto, Cui Hong, Kazuaki Yoshioka, Noriko TakuwaToshishige Shibamoto, Yoh Takuwa
- Organizer
  The 18th International Vascular Biology Meeting 2014 (IVBM 2014)
- Place of Presentation
  みやこめっせ（京都府京都市）
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-26460292
[Presentation] クラスII 型PI3 キナーゼ-C2α によるTGFβ 血管内皮作用の調節機構
- Author(s)
  安藝　翔、吉岡和晃、多久和典子、岡本安雄、多久和　陽
- Organizer
  第61回　中部日本生理学会
- Place of Presentation
  名古屋市立大学桜山キャンパス（愛知県名古屋市）
- Year and Date
  2014-11-06 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-26460292
[Presentation] クラスIIα型PI3K-C2αはALK5 内在化及び足場タンパクSARA のエンドソームへの動員を制御しTGF-1-Smad2/3 を介した血管新生を調節する
- Author(s)
  安藝翔、吉岡和晃、岡本安雄、多久和典子、多久和陽
- Organizer
  第56回日本脂質生化学会
- Place of Presentation
  近畿大学東大阪キャンパス
- Year and Date
  2014-06-06 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-25670162
[]

1. TAKUWA Yoh (60171592)

# of Collaborated Projects: 10 results

# of Collaborated Products: 80 results
2. TAKUWA Noriko (70150290)

# of Collaborated Projects: 9 results

# of Collaborated Products: 58 results
3. SUGIMOTO Naotoshi (80272954)

# of Collaborated Projects: 7 results

# of Collaborated Products: 11 results
4. OKAMOTO Yasuo (80293877)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
5. Morishige Jun-ichi (50423405)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. 飯野賢治 (60595453)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 竹村博文 (20242521)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 櫻田惣太郎 (00215691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 内藤尚道 (30570676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 木村圭一 (50372488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 中瀬順介 (50584843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 鳥越甲順 (50126603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 葛巻徹 (50396909)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. BISWAS Kuntal

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. AKI Sho

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
16. Kuda Yuichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MOHRI Hiromi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SHIMIZU Shouta

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. FUJII Miki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. YASUDA Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 此下忠志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 石丸和宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 川尻剛照

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 高村雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

yoshioka kazuaki 吉岡 和晃

YOSHIOKA Kazuaki 吉岡 和晃

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Here is the English translation of the title: Functional Structure of the Adventitial Vasa Vasorum in the Aorta and the Elucidation of the Pathogenic Mechanism of Diseases Caused by Its DisruptionPrincipal Investigator

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Regulation of lung stem cells through intracellular clearance by lipid phosphatasePrincipal Investigator

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Physiological roles of Phosphoinositide-specific phosphatase in lung development and maturation through regulating membrane trafficking.Principal Investigator

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Regulation of membrane trafficking through PI(3)P-metabolizing enzymes in endothelial cells.Principal Investigator

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Class II PI3 kinase C2alpha has an essential role in angiogenesis and vascular homeostasis through regulating endosomal traffickingPrincipal Investigator

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yoshioka kazuaki 吉岡和晃

YOSHIOKA Kazuaki 吉岡和晃