OKAZAWA HIDEKI 岡澤秀樹

… Alternative Names

OKAZAWA Hideki 岡澤秀樹

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Researcher Number	80334126
Other IDs
Affiliation (based on the past Project Information) *help	2014: 神戸大学, 医学(系)研究科(研究院), 医学研究員 2012 – 2014: 神戸大学, 医学(系)研究科(研究院), 研究員 2009: 群馬大学, 生体調節研究所, 助教 2007: Gunma University, Institute for Molecular and Cellular Regulation, Assistant professor 2001 – 2006: 群馬大学, 生体調節研究所, 助手
Review Section/Research Field	Principal Investigator General medical chemistry / Pathological medical chemistry / Cell biology Except Principal Investigator Biological Sciences / Functional biochemistry
Keywords	Principal Investigator SHPS-1 / マクロファージ / Cytokine / Phagocytosis / Macrophage / Dendritic cell / チロシンホスファターゼ / チロシンリン酸化 / サイトカイン / 貪食 … More / 樹状細胞 / 免疫学 / 炎症 / 癌 / 生体分子 / シグナル伝達 / 赤血球 / SHP-1 / CD47 / 食作用 / 細胞間情報伝達 … More Except Principal Investigator CD47 / SHPS-1 / 細胞接着 / SAP-1 / 細胞増殖 / SIRPβ / Ectodomain shedding / 細胞運動 / がん / Cdc42 / Rac / SHP-2 / チロシンホスファターゼ / Macrophage function / Cell Adhesion / Cell migration / Cell-cell signaling / 神経シナプス機能 / 血小板 / 細胞内シグナル伝達 / マクロファージ機能 / 細胞間シグナル伝達 / 樹状細胞 / NKT細胞 / 生体分子 / シグナル伝達 / 酵素 / 癌 / コンタクトインヒビション / 接触阻害 / マクロファージ / 細胞接触 / 低分子量G蛋白質 Less

The double regulation of intestinal immunity and its implications in inflammatory bowel diseasePrincipal Investigator
- Principal Investigator
  
  OKAZAWA HIDEKI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
Positive and negative regulation of macrophage/ dendritic cell functions by novel paired receptorsPrincipal Investigator
- Principal Investigator
  
  OKAZAWA Hideki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Gunma University
Protein tyrosine phosphatases and regulation of cancer cell adhesion/migration
- Principal Investigator
  
  MATOZAKI Takashi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
新しい細胞間情報伝達システムによるマクロファージ貧食作用の制御Principal Investigator
- Principal Investigator
  
  岡澤秀樹
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Gunma University
細胞の増殖シグナルと接着シグナルのクロストーク制御機構とヒトがんにおける異常
- Principal Investigator
  
  的崎尚
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
Research for physiological roles of the CD47-SHPS-1 system.
- Principal Investigator
  
  MATOZAKI Takashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Gunma University
細胞の増殖と接着の制御機構
- Principal Investigator
  
  MATOZAKI Takashi
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University

All 2015 2014 2013 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Dendritic cell SIRPα regulates homeostasis of dendritic cells in lymphoid organs2015
- Author(s)
  Washio K, Kotani T, Saito Y, Respatika D, Murata Y, Kaneko Y, Okazawa H, Ohnishi H, Fukunaga A, Nishigori C, Matozaki T.
- Journal Title
  
  Genes Cells
  
  Volume: - Issue: 6 Pages: 00-00
- DOI
  10.1111/gtc.12238
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590380, KAKENHI-PUBLICLY-25112709, KAKENHI-PROJECT-25461468, KAKENHI-PROJECT-26291022, KAKENHI-PROJECT-26670142, KAKENHI-PROJECT-15K08532, KAKENHI-PROJECT-26860210
[Journal Article] Role of the protein tyrosine phosphatase Shp2 in homeostasis of the intestinal epithelium2014
- Author(s)
  Yamashita H, Kotani T, Park JH, Murata Y, Okazawa H, Ohnishi H, Ku Y, Matozaki T
- Journal Title
  
  PLoSOne
  
  Volume: 9 Issue: 3 Pages: e92904-e92904
- DOI
  10.1371/journal.pone.0092904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370061, KAKENHI-PROJECT-24590380, KAKENHI-PUBLICLY-25112709, KAKENHI-PUBLICLY-25114709, KAKENHI-PROJECT-25460366
[Journal Article] Tyrosine phosphorylation of R3 subtype receptor-type protein tyrosine phosphatases and their complex formations with Grb2 or Fyn.2010
- Author(s)
  Murata, Y., Mori, M., Kotani, T., Supriatna, Y., Okazawa, H., Kusakari, S., Saito, Y., Ohnishi, H., Matozaki, T.
- Journal Title
  
  Genes Cells 15
  
  Pages: 513-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Promotion of cell spreading and migration by vascular endothelial-protein tyrosine phosphatase (VE-PTP) in cooperation with integrins.2010
- Author(s)
  Mori, M., Murata, Y., Kotani, T., Kusakari, S., Ohnishi, H., Saito, Y., Okazawa, H., Ishizuka, T., Mori, M., Matozaki, T.
- Journal Title
  
  J. Cell. Physiol. 224
  
  Pages: 195-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] SAP-1 is a microvillus-specific protein tyrosine phosphatase that modulates intestinal tumorigenesis.2009
- Author(s)
  Sadakata, H., Okazawa, H., Sato, T., Supriatna, Y., Ohnishi, H., Kusakari, S., Murata, Y., Ito, T., Nishiyama, U., Minegishi, T., Harada, A., Matozaki, T.
- Journal Title
  
  Genes Cells 14
  
  Pages: 295-308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Protein tyrosine phosphatase SHP-2: A proto-oncogene product that promotes Ras activation.2009
- Author(s)
  Matozaki, T., Murata, Y., Saito, Y., Okazawa, H., Ohnishi, H.
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 1786-1793
- NAID
  10027195202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Functions and molecular mechanisms of the CD47-SIRPα signalling pathway.2009
- Author(s)
  Matozaki, T., Murata, Y., Okazawa, H., Ohnishi, H.
- Journal Title
  
  Trends Cell Biol. 19
  
  Pages: 72-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Trans-endocytosis of CD47 and SHPS-1 and its role in regulation of the CD47-SHPS-1 system.2008
- Author(s)
  Kusakari, S., Ohnishi, H., Jin, F. -J., Kaneko, Y., Murata, T., Murata, Y., Okazawa, H., Matozaki, T.
- Journal Title
  
  J. Cell Sci. 121
  
  Pages: 1213-1223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Negative regulation by SHPS-1 of Toll-like receptor-dependent proinflammatory cytokine production in macrophages2008
- Author(s)
  Miyake, A., Murata, Y., Okazawa. H., Ikeda, H., Niwayama, Y., Ohnishi, H., Hirata, Y., Matozaki, T.
- Journal Title
  
  Genes to Cells 13
  
  Pages: 209-219
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Journal Article] Essential roles of SHPS-1 in induction of contact hypersensitivity of skin.2008
- Author(s)
  Motegi, S., Okazawa, H., Murata, Y., Kanazawa, Y., Saito, Y., Kobayashi, H., Ohnishi, H., Oldenborg, P. -A., Ishikawa, O., Matozaki, T.
- Journal Title
  
  Immunol. Lett. 121
  
  Pages: 52-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Negative regulation by SHPS-1 of Toll-like receptor-dependent proinflammatory cytokine production in macrophages.2008
- Author(s)
  Miyake, A., Murata, Y., Okazawa, H., Ikeda, H., Niwayama, Y., Ohnishi, H., Hirata, Y., Matozaki, T.
- Journal Title
  
  Genes Cells 3
  
  Pages: 209-219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Regulation by Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 of α-Galactosylceramide-induced antimetastatic activity and Th1 and Th2 responses of NKT cells2007
- Author(s)
  Okajo, J., Kaneko, Y., Murata, Y., Tomizawa, T., Okuzawa, C., Saito, Y., Kaneko, Y., Ishikawa-Sekigami, T., Okazawa. H., Ohnishi, H., Matozaki, T., and Nojima, Y.
- Journal Title
  
  Journal of Immunology 178
  
  Pages: 6164-6172
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Journal Article] Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 mutant mice2007
- Author(s)
  Tomizawa, T., Kaneko, Y., Kaneko, Y., Saito, Y., Ohnishi, H., Okajo, J., Okuzawa, C., Ishikawa-Sekigami, T., Murata, Y., Okazawa. H., Okamoto, K., Nojima, Y., Matozaki, T.
- Journal Title
  
  Journal of Immunology 179
  
  Pages: 869-877
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Journal Article] Regulation by Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 of α-galactosylceramide-induced antimetastatic activity and Th1 and Th2 responses of NKT cells.2007
- Author(s)
  Okajo, J., Kaneko, Y., Murata, Y., Tomizawa, T., Okuzawa, C., Saito, Y., Kaneko, Y., Ishikawa-Sekigami, T., Okazawa, H., Ohnishi, H., Matozaki, T. Nojima, Y.
- Journal Title
  
  J. Immunol. 178
  
  Pages: 6164-6172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in SHPS-1 mutant mice.2007
- Author(s)
  Tomizawa, T., Kaneko, Y., Kaneko, Y., Saito, Y., Ohnishi, H., Okajo, J., Okuzawa, C., Ishikawa-Sekigami, T., Murata, Y., Okazawa, H., Okamoto, K., Nojima, Y. Matozaki, T.
- Journal Title
  
  J. Immunol. 179
  
  Pages: 869-877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] CD47 regulation of epithelial cell spreading and migration, and its signal transduction.2006
- Author(s)
  Shinohara, M., Ohyama, N., Murata, Y., Okazawa, H., Ohnishi, H., Ishikawa, O., Matozaki, T.
- Journal Title
  
  Cancer Sci. 97
  
  Pages: 889-895
- NAID
  10018767488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] SHPS-1 promotes the survival of circulating erythrocytes through inhibition of phagocytosis by splenic macrophages.2006
- Author(s)
  Ishikawa-Sekigami, T., Kaneko, Y., Okazawa, H., Tomizawa, T., Okajo, J., Saito, Y., Okuzawa, C., Sugawara-Yokoo, M., Nishiyama, U., Ohnishi, H., Matozaki, T. Nojima, Y.
- Journal Title
  
  Blood 107
  
  Pages: 341-348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Mutational analysis of the mechanism of negative regulation by Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 of phagocytosis in macrophages2006
- Author(s)
  Ikeda, H., Okazawa. H., Ohnishi, H., Murata, Y., Oldenborg, P. -A., and Matozaki, T.
- Journal Title
  
  Journal of Immunology 177
  
  Pages: 3123-3132
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Journal Article] Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 regulates the induction of Langerhans cell maturation2006
- Author(s)
  Fukunaga, A., Nagai, H., Yu, X., Oniki, S., Okazawa. H., Motegi, S., Suzuki, R., Honma, N., Matozaki, T., Nishigori, C., and Horikawa, T.
- Journal Title
  
  European Journal of Immunology 3
  
  Pages: 3216-3226
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Journal Article] Mutational analysis of the mechanism of negative regulation by SHPS-1 of phagocytosis in macrophages.2006
- Author(s)
  Ikeda, H., Okazawa, H., Ohnishi, H., Murata, Y., Oldenborg, P. -A. Matozaki, T.
- Journal Title
  
  J. Immunol. 177
  
  Pages: 3123-3132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system.2005
- Author(s)
  Okazawa, H.et al.
- Journal Title
  
  The Journal of Immunology 174巻・4号
  
  Pages: 2004-2011
- Data Source
  KAKENHI-PROJECT-15770119
[Journal Article] Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system.2005
- Author(s)
  Okazawa, H., et al.
- Journal Title
  
  J.Immunol. 174巻・4号
  
  Pages: 2004-2011
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system.2005
- Author(s)
  Okazawa, H., et al.
- Journal Title
  
  J.Immunol. 174巻・4号
  
  Pages: 2004-2011
- Data Source
  KAKENHI-PROJECT-14028009
[Journal Article] Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system.2005
- Author(s)
  Okazawa, H., Motegi, S., Ohyama, N., Ohnishi, H., Tomizawa, T., Kaneko, Y., Oldenborg, P. -A., Ishikawa, O., Matozaki, T.
- Journal Title
  
  J. Immunol. 174
  
  Pages: 2004-2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] 樹状細胞及び二次リンパ組織の恒常性維持におけるＳＩＲＰαの役割2014
- Author(s)
  鷲尾健、小谷武徳、レスパティカ　ダトゥ、村田陽二、岡澤秀樹、大西浩史、福永淳、錦織千佳子、的崎尚
- Organizer
  第6回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  三重大学
- Data Source
  KAKENHI-PROJECT-24590380
[Presentation] SIRPα-CD47 system regulates the homeostasis of dendritic cells in lymphoid tissues2014
- Author(s)
  Ken Washio, Takenori Kotani, Datu Respatika, Yoji Murata, Hideki Okazawa, Hiroshi Ohnishi, Atsushi Fukunaga, Chikako Nishigori, and Takashi Matozaki
- Organizer
  ワシントン大学・神戸大学国際合同シンポジウム
- Place of Presentation
  Seattle, USA（ワシントン大学）
- Data Source
  KAKENHI-PROJECT-24590380
[Presentation] 腸上皮の恒常性維持におけるチロシンホスファターゼShp2の役割2014
- Author(s)
  小谷武徳、山下博成、朴貞河、村田陽二、岡澤秀樹、大西浩史、具英成、的崎尚
- Organizer
  第6回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  三重大学
- Data Source
  KAKENHI-PROJECT-24590380
[Presentation] SIRPαによる脾臓T細胞の恒常性の調節2013
- Author(s)
  橋本美穂、齊藤泰之、金子哲也、大西浩史、草苅伸也、小谷武徳、村田陽二、岡澤秀樹、的崎尚、
- Organizer
  第60回北関東医学会総会
- Place of Presentation
  群馬大学医学部
- Data Source
  KAKENHI-PROJECT-24590380
[Presentation] Roles of the protein tyrosine phosphatase Shp2 in homeostasis of the intestinal epithelium2013
- Author(s)
  Takenori Kotani, Hironori Yamashita, Yoji Murata, Hideki Okazawa, Hiroshi Ohnishi, and Takashi Matozaki
- Organizer
  FASEB
- Place of Presentation
  SteamboatSprings, USA
- Data Source
  KAKENHI-PROJECT-24590380
[Presentation] SIRPα-CD47 system regulates the homeostasis of dendritic cells in lymphoid tissues2013
- Author(s)
  Ken Washio, Takenori Kotani, Datu Respatika, Yoji Murata, Hideki Okazawa, Hiroshi Ohnishi, Atsushi Fukunaga, Chikako Nishigori, and Takashi Matozaki
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉（幕張メッセ）
- Data Source
  KAKENHI-PROJECT-24590380
[Presentation] 腸上皮の恒常性維持におけるチロシンホスファターゼShp2の役割2013
- Author(s)
  小谷武徳、山下博成、村田陽二、岡澤秀樹、大西浩史、具英成、的崎尚
- Organizer
  第12回生体機能研究会
- Place of Presentation
  群馬（伊香保）
- Data Source
  KAKENHI-PROJECT-24590380
[Presentation] The protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM in the intestinal epithelium2013
- Author(s)
  Takashi Matozaki, Yoji Murata, Takenori Kotani, Yana Supriatna, Hideki Okazawa, and Hiroshi Ohnishi
- Organizer
  FASEB
- Place of Presentation
  SteamboatSprings, USA
- Data Source
  KAKENHI-PROJECT-24590380
[Presentation] 腸上皮の恒常性維持におけるチロシンホスファターゼShp2 の役割2013
- Author(s)
  山下博成、小谷武徳、村田陽二、岡澤秀樹、大西浩史、具英成、的崎尚
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  神奈川（パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-24590380
[Presentation] R3 受容体型チロシンホスファターゼの発現、局在と生理機能2013
- Author(s)
  的崎尚、村田陽二、小谷武徳、Yana Supriatna、森宗昌、岡澤秀樹、大西浩史
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  兵庫（神戸国際会議場、神戸ポートピアホテル）
- Data Source
  KAKENHI-PROJECT-24590380
[Presentation] 腸上皮の恒常性維持におけるチロシンホスファターゼShp2の役割2013
- Author(s)
  小谷武徳、山下博成、村田陽二、岡澤秀樹、大西浩史、具英成、的崎尚
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  神奈川（パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-24590380
[Presentation] 受容体型チロシンホスファターゼSAP-1 による腸管免疫制御2013
- Author(s)
  村田陽二、小谷武徳、Supriatna Yana 、森宗昌、草苅伸也、岡澤秀樹、大西浩史、的崎尚
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  神奈川（パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-24590380
[Presentation] Promotion by VE-PTP of lamellipodium formation in cooperation with Ras and integrin.2009
- Author(s)
  M ori, M., Murata, Y., Ohnishi, H., Okazawa, H., Kotani, T., Saito, Y., Mori, M. Matozaki, T.
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] Tyrosine phosphorylation of SAP-1, a receptor-type protein tyrosine phosphatase, and its association with Grb2.2009
- Author(s)
  Murata, Y., Kotani, Supriatna, Y., Mori, M., Okazawa, H., Ohnishi, H., Saito, Y., Matozaki, T.
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] クラス3受容体型チロシンホスファターゼの機能と病態への関与2008
- Author(s)
  Y ana Supriatna、岡澤秀樹、村田陽二、大西浩史、的崎尚
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] チロシンホスファターゼによるがん、炎症性腸炎の制御2008
- Author(s)
  的崎尚、岡澤秀樹、村田陽二、大西浩史
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] SAP-1 is a microvillus-specific protein tyrosine phosphatase that regulates intestinal tumorigenesis.2008
- Author(s)
  S adakata, H., Okazawa, H., Supriatna, Y., Ohnishi, H., Murata, Y., Matozaki, T.
- Organizer
  FASEB Summer Research Conferences
- Place of Presentation
  Snowmass, Colorado(USA)
- Year and Date
  2008-07-13
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] Trans-endocytosis of CD47-SHPS-1 system and its molecular mechanism.2007
- Author(s)
  K usakari, S., Ohnishi, H., Okazawa, H., Murata, T., Murata, Y., Matozaki, T.
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] Negative regulation by SHPS-1 of Toll-like receptor mediated cytokine production by macrophages2007
- Author(s)
  Miyake, A., Murata, Y., Okazawa, H., Ikeda, H., Onhishi, H., Hirata, Y., Matozaki, T.
- Organizer
  EuroPhosphatases 2007 "Protein Phosphatases in Health and Disease"
- Place of Presentation
  Aveiro Portugal
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Presentation] SHPS-1による皮膚免疫とToll様受容体を介したサイトカイン産生の制御2007
- Author(s)
  茂木精一郎、岡澤秀樹、小林久江、村田陽二、大西浩史、石川治、的崎尚
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] An essential role of SHPS-1 in proper development of dendritic cells for induction of Th17-mediated autoimmune diseases2007
- Author(s)
  Saito, Y., Kaneko, Y., Kaneko, Y., Okuzawa, C., Sekigami, T., Okajo, J., Tomizawa, T., Murata, Y., Okazawa, H., Onhishi, H., Matozaki, T., Nojima, Y.
- Organizer
  The 37th annual meeting of the Japanese Society for Immunology
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Presentation] Roles of SHPS-1 and its family protein SIRPβ in regulation of macrophage phagocytosis2007
- Author(s)
  Okazawa, H., Motegi, S., Ikeda, H., Morimoto, N., Ishikawa-Sekigami, T., Hayashi, A., Murata, Y., Ohnishi, H., Matozaki, T.
- Organizer
  The 59th annual meeting of the Japan Society for Cell Biology The 40th annual mmeting of the Japanese Society of Developmental Biologists
- Place of Presentation
  Fukuoka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Presentation] Functions and the molecular mechanism of the CD47-SHPS-1 System2007
- Author(s)
  Matozaki T., Ohnishi, H., Okazawa, H., Murata, Y.
- Organizer
  BMB2007
- Place of Presentation
  Pacifico Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Presentation] Regulation by SHPS-1 of skin immunity and of Toll-like receptor-mediated cytokine production2007
- Author(s)
  Motegi, S., Okazawa, H., Kobayashi, H., Murata, Y., Ohnishi, H., Ishikawa, O., Matozaki, T.
- Organizer
  The 66th annual meeting of the Japanese Cancer Asociation
- Place of Presentation
  PacificoYokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Presentation] Roles of SHPS-1 and its family protein SIRPβ in regulation of macrophage phagocytosis2007
- Author(s)
  Okazawa, H., 他
- Organizer
  第59回日本細胞生物学会大会第40回日本発生生物学会大会合同大会
- Place of Presentation
  福岡国際会議場(福岡)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Presentation] Regulation by SHPS-1 of Toll-like receptor-mediated cytokine production by macrophages2007
- Author(s)
  Miyake, A., Murata, Y., Okazawa, H., Ikeda, H., Onhishi, H., Hirata, Y., Matozaki, T.
- Organizer
  The 37th annual meeting of the Japanese Society for Immunology
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Presentation] Negative regulation by SHPS-1 of Toll-like receptor-mediated cytokine production by macrophages2007
- Author(s)
  Miyake, A., Murata, Y., Okazawa, H., Ikeda, H., Niwayama, Y., Onhishi, H., Hirata, Y., Matozaki, T.
- Organizer
  The 6th Conference of Biofunctions
- Place of Presentation
  Hakone
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Presentation] An essential role of SHPS-1 in development of Th17-mediated inflammatory autoimmune diseases2007
- Author(s)
  Ohnishi, H., Kaneko, Y., Okazawa, H., Murata, Y., Matozaki, T.
- Organizer
  EuroPhosphatases 2007 "Protein Phosphatases in Health and Disease"
- Place of Presentation
  Aveiro Portugal
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Presentation] Regulation by CD47-SHPS-1 system of neurite development.2007
- Author(s)
  M urata, T., Ohnishi, H., Kusakari, S., Murata, Y., Okazawa, H., Furuya, N., Matozaki, T.
- Organizer
  Neurosciense 2007
- Place of Presentation
  San Diego Convention center(サンディエゴ)
- Year and Date
  2007-11-03
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] Regulation by SHPS-1 of skin immunity and of Toll-like receptor-mediated cytokine production2007
- Author(s)
  Motegi, S., Okazawa, H., Kobayashi, H., Murata, Y., Ohnishi, H., Ishikawa, O., Matozaki, T.
- Organizer
  The 37th annual meeting of the Japanese Society for Immunology
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Presentation] Regulation by SHPS-1 of Toll-like receptor-mediated cytokine production by macrophages2007
- Author(s)
  Miyake, A., Murata, Y., Okazawa, H., Ikeda, H., Onhishi, H., Hirata, Y., Matozaki, T.
- Organizer
  BMB2007
- Place of Presentation
  Pacifico Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Presentation] CD47 promotes neuronal development through Src-and FRG/Vav2-mediated activation of Rac and Cdc42.2006
- Author(s)
  M urata, T., Ohnishi, H., Okazawa, H., Murata, Y., Kusakari, S., Hayashi, Y., Miyashita, M., Furuya, N., Matozaki, T.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2006-06-18
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] Regulation by Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 of α-Galactosylceramide-induced antimetastatic activity and Th1 and Th2 responses of NKT cells2006
- Author(s)
  Okajo, J., Kaneko, Y., Murata, Y., Okazawa, H., Ohnishi, H., Nojima, Y., Matozaki, T.
- Organizer
  The 65th annual meeting of the Japanese Cancer Asociation
- Place of Presentation
  Pacifico Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Presentation] Mutational analysis of the mechanism of negative regulation by Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 of phagocytosis in macrophages2006
- Author(s)
  Ikeda, H., Okazawa, H., Murata, Y., Ohnishi, H., Matozaki, T.
- Organizer
  The 65th annual meeting of the Japanese Cancer Asociation
- Place of Presentation
  Pacifico Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590256
[Presentation] NKT細胞の活性化と癌転移抑制におけるSHPS-1の役割2006
- Author(s)
  岡上準、金子和光、村田陽二、岡澤秀樹、大西浩史、野島美久、的崎尚, 他
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2006-09-28
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] A Novel Intercellular Communication System, The CD47-SHPS-1 System, in Neuronal Network.2005
- Author(s)
  Ohnishi, H., Miyashita, M., Murata, T., Kaneko, Y., Okazawa, H., Matozaki, T.
- Organizer
  ISN-ESN:20th Biennial Meeting International Society for Neurochemistry jointly with the European Society for Neurochemistry
- Place of Presentation
  Congress Innsbruck(Innsbruck, Austria)
- Year and Date
  2005-08-25
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] 腸管におけるCEACAM20の発現と腸内細菌叢を介した発現制御
- Author(s)
  北村泰明、村田陽二、朴貞河、小谷武徳、岡澤秀樹、東健、的崎尚
- Organizer
  第13回生体機能研究会
- Place of Presentation
  ホテルパーク・長良川温泉（岐阜県・岐阜市）
- Year and Date
  2014-07-18 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-24590380
[Presentation] 樹状細胞及び二次リンパ組織の恒常維持におけるSIRPαの役割
- Author(s)
  鷲尾健、小谷武徳、レスパティカダトゥ、村田陽二、齊藤泰之、金子和光、岡澤秀樹、大西浩史、福永淳、錦織千佳子、的崎尚
- Organizer
  第13回生体機能研究会
- Place of Presentation
  ホテルパーク・長良川温泉（岐阜県・岐阜市）
- Year and Date
  2014-07-18 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-24590380
[Presentation] 腸管におけるCEACAM20の発現と腸内細菌叢を介した発現制御 / Expression of CEACAM20 in intestine epithelial cells and regulation of its expression by intestinal microflora
- Author(s)
  北村泰明、村田陽二、朴貞河、今田慎也、小谷武徳、岡澤秀樹、東健、的崎尚
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館・グランドプリンスホテル京都（京都府・京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24590380
[Presentation] Essential role of SIRPα on dendritic dells in organization and homeostasis of the spleen
- Author(s)
  Ken Washio, Takenori Kotani, Datu Respatika, Yoji Murata, Yasuyuki Saito, Hideki Okazawa, Hiroshi Ohnishi, Atsushi Fukunaga, Chikako Nishigori, Takashi Matozaki
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24590380

1. MATOZAKI Takashi (80252782)

# of Collaborated Projects: 4 results

# of Collaborated Products: 26 results
2. OHNISHI Hiroshi (70334125)

# of Collaborated Projects: 3 results

# of Collaborated Products: 26 results
3. MURATA Yoji (60400735)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results
4. OHE Yoshihide (80125830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KANEKO Yoriaki (00334095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KOBAYASHI Hisae (80234839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OKAZAWA HIDEKI 岡澤 秀樹

OKAZAWA Hideki 岡澤 秀樹

Research Projects

Research Products

Co-Researchers

The double regulation of intestinal immunity and its implications in inflammatory bowel diseasePrincipal Investigator

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Positive and negative regulation of macrophage/ dendritic cell functions by novel paired receptorsPrincipal Investigator

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Protein tyrosine phosphatases and regulation of cancer cell adhesion/migration

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新しい細胞間情報伝達システムによるマクロファージ貧食作用の制御Principal Investigator

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細胞の増殖シグナルと接着シグナルのクロストーク制御機構とヒトがんにおける異常

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Research for physiological roles of the CD47-SHPS-1 system.

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細胞の増殖と接着の制御機構

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[Journal Article] Dendritic cell SIRPα regulates homeostasis of dendritic cells in lymphoid organs2015

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Journal Title

DOI

Data Source

[Journal Article] Role of the protein tyrosine phosphatase Shp2 in homeostasis of the intestinal epithelium2014

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DOI

Data Source

[Journal Article] Tyrosine phosphorylation of R3 subtype receptor-type protein tyrosine phosphatases and their complex formations with Grb2 or Fyn.2010

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[Journal Article] Promotion of cell spreading and migration by vascular endothelial-protein tyrosine phosphatase (VE-PTP) in cooperation with integrins.2010

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[Journal Article] SAP-1 is a microvillus-specific protein tyrosine phosphatase that modulates intestinal tumorigenesis.2009

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[Journal Article] Protein tyrosine phosphatase SHP-2: A proto-oncogene product that promotes Ras activation.2009

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NAID

Data Source

[Journal Article] Functions and molecular mechanisms of the CD47-SIRPα signalling pathway.2009

Author(s)

Journal Title

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[Journal Article] Trans-endocytosis of CD47 and SHPS-1 and its role in regulation of the CD47-SHPS-1 system.2008

Author(s)

OKAZAWA HIDEKI 岡澤秀樹

OKAZAWA Hideki 岡澤秀樹