Ojima Hidenori 尾島英知

… Alternative Names

尾島英知オジマヒデノリ

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Researcher Number	80342905
Affiliation (Current)	2025: 地方独立行政法人栃木県立がんセンター(研究所), 研究所－分子病理研究分野, 副研究所長
Affiliation (based on the past Project Information) *help	2023: 地方独立行政法人栃木県立がんセンター(研究所), 研究所－分子病理研究分野, 副研究所長 2022: 慶應義塾大学, 医学部(信濃町), 准教授 2016 – 2019: 慶應義塾大学, 医学部(信濃町), 准教授 2014 – 2015: 慶應義塾大学, 医学部, 准教授
Review Section/Research Field	Principal Investigator Experimental pathology / Basic Section 49020:Human pathology-related
Keywords	Principal Investigator 血管新生 / データベース / 遺伝子発現 / 新鮮切除検体 / 細胞株 / 胆道領域がん / 病理学 / 肝内胆管がん / 放射線感受性 / 胆道領遺伝子発現 … More / GSEA / 遺伝子変異 / 分子病理学的 / 細胆管細胞癌 / 前臨床試験 / 免疫染色 Less

Research Projects
(3 results)
Research Products
(18 results)

腫瘤形成型肝内胆管癌における血管新生関連分子の発現意義と発がん分子病理機構の解明Principal Investigator
- Principal Investigator
  
  尾島英知
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Tochigi Cancer Center (institute)
  Keio University
Identification of gene expression and abnormalities that define clinicopathological features of biliary tract carcinoma and their application in diagnosis and treatmentPrincipal Investigator
- Principal Investigator
  
  Ojima Hidenori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Keio University
Investigation of molecular mechanisms involved in carcinogenesis, proliferation and progression of billiary tract carcinoma and its application to clinical treatmentPrincipal Investigator
- Principal Investigator
  
  Ojima Hidenori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Keio University

All 2024 2023 2022 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Synergistic and Pharmacotherapeutic Effects of Gemcitabine and Cisplatin Combined Administration on Biliary Tract Cancer Cell Lines2019
- Author(s)
  Sakamoto Yasunari、Yamagishi Seri、Okusaka Takuji、Ojima Hidenori
- Journal Title
  
  Cells
  
  Volume: 8 Issue: 9 Pages: 1026-1026
- DOI
  10.3390/cells8091026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08769
[Journal Article] PI3K-mTOR pathway identified as a potential therapeutic target in biliary tract cancer using a newly established patient-derived cell panel assay2018
- Author(s)
  Sakamoto Y., Yamagishi S., Tanizawa Y., Tajimi M., Okusaka T., Ojima H
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 48 Issue: 4 Pages: 396-399
- DOI
  10.1093/jjco/hyy011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08769
[Journal Article] 肝胆膵領域に対する病理学的治療効果判定2017
- Author(s)
  尾島英知, 益田悠貴, 前原純樹, 上野彰久, 坂本康成
- Journal Title
  
  病理と臨床
  
  Volume: 35 Pages: 1002-1009
- Data Source
  KAKENHI-PROJECT-17K08769
[Journal Article] Establishment of various biliary tract carcinoma cell lines and xenograft models for appropriate preclinical studies.2016
- Author(s)
  Ojima H, Yamagishi S, Shimada K, Shibata T
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 22 Issue: 40 Pages: 9035-9038
- DOI
  10.3748/wjg.v22.i40.9035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460501
[Journal Article] Heat Shock Protein 90 Is a Potential Therapeutic Target in Cholangiocarcinoma.2015
- Author(s)
  Shirota T, Ojima H, Hiraoka N, Shimada K, Rokutan H, Arai Y, Kanai Y, Miyagawa　S, Shibata T.
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: 14 Issue: 9 Pages: 1985-93
- DOI
  10.1038/ng.3375
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460501, KAKENHI-PROJECT-26461040, KAKENHI-PROJECT-25290074
[Journal Article] Genomic spectra of biliary tract cancer.2015
- Author(s)
  Nakamura H, Arai Y, Totoki Y, Shirota T, Elzawahry A, Kato M, Hama N, Hosoda　F, Urushidate T, Ohashi S, Hiraoka N, Ojima H, Shimada K, Okusaka T, Kosuge T,　Miyagawa S, Shibata T.
- Journal Title
  
  Nat Genet.
  
  Volume: 47 Issue: 9 Pages: 1003-10
- DOI
  10.1158/1535-7163.mct-15-0069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460501
[Presentation] 肝嚢胞性疾患の病理2024
- Author(s)
  尾島英知
- Organizer
  NCC HBP Cancer
- Invited
- Data Source
  KAKENHI-PROJECT-22K06985
[Presentation] HILAR CHOLANGIOCARCINOMA WITHOUT MACROSCOPIC MASS FORMATION CLASSIFIED INTO EXTRAHEPATIC CHOLANGIOCARCINOMA BASED ON MOLECULAR PATHOLOGIC STUDIES2023
- Author(s)
  Yuki Masuda, Hidenori Ojima, et al.
- Organizer
  United European Gastroenterology 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06985
[Presentation] 肝臓病理の基礎と診断までのアプローチ2023
- Author(s)
  尾島英知
- Organizer
  日本肝臓学会 School of Hepatology in Kanazawa
- Invited
- Data Source
  KAKENHI-PROJECT-22K06985
[Presentation] 日本胆道学会認定指導医養成講座 6 胆管内乳頭状腫瘍(IPNB)の基本事項の確認と臨床病理学的意義2022
- Author(s)
  尾島英知
- Organizer
  第 58 回日本胆道学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06985
[Presentation] Gamma-Synuclein is a novel prognostic marker and promotes tumor cell migration in biliary tract carcinoma.2020
- Author(s)
  Yusuke Takemura, Hidenori Ojima, Go Oshima, Naoto Kubota, Masahiro Shinoda, Minoru Kitago, Hiroshi Yagi, Yuta Abe, Shutaro Hori, Yuki Masuda, Yoko Nishimura, Taizo Hibi, Michiie Sakamoto, Yuko Kitagawa
- Organizer
  Gastrointestinal Cancers Symposium 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08769
[Presentation] 病理形態学を基盤とした、胆道悪性腫瘍の進展に関わる分子機構の解明2019
- Author(s)
  尾島英知
- Organizer
  第65回日本病理学会秋期特別総会 (学術研究賞演説)
- Invited
- Data Source
  KAKENHI-PROJECT-17K08769
[Presentation] SYNERGISTIC EFFECTS AND PHARMACOTHERAPEUTIC ACTIVITY OF GEMCITABINE AND CISPLATIN COMBINATION THERAPY IN BILIARY TRACT CANCER CELL LINES2019
- Author(s)
  Yasunari Sakamoto, Seri Yamagishi, Takuji Okusaka, Hidenori Ojima.
- Organizer
  United European Gastroenterology Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08769
[Presentation] 肝腫瘍の病理と臨床、その基本事項と未来像. ～NASHや糖尿病との関連も含めて～2018
- Author(s)
  尾島英知
- Organizer
  日本超音波医学会第48回北海道地方会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08769
[Presentation] Establishment of a preclinical study system for the discovery of ant-cholangiocarcinoma drug2017
- Author(s)
  Hidenori Ojima, Seri Yamagishi, Yasuhito Arai, Yasunari Sakamoto, Takuji Okusaka. Tatsuhiro Shibata
- Organizer
  The Cholangiocarcinoma Foundation, 4th Annual International Conference
- Place of Presentation
  Salt Lake City, USA
- Year and Date
  2017-02-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460501
[Presentation] 胆道癌モデルと臨床検体を用いた大規模前臨床試験システム確立の試み2015
- Author(s)
  尾島英知, 柴田龍弘, 金井弥栄
- Organizer
  第51回日本胆道学会学術集会
- Place of Presentation
  ホテル東日本宇都宮（栃木県宇都宮市）
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-26460501
[Presentation] 胆管がん細胞株を用いたゲムシタビンとシスプラチン併用による相乗効果の検討2015
- Author(s)
  山岸せり, 尾島英知, 坂本康成, 金井弥栄
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26460501
[Presentation] Pathology of the Liver Tumor, an Update2015
- Author(s)
  4.尾島英知
- Organizer
  第74回日本放射線学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-04-17
- Invited
- Data Source
  KAKENHI-PROJECT-26460501

Ojima Hidenori 尾島 英知

尾島 英知 オジマ ヒデノリ

Research Projects

Research Products

腫瘤形成型肝内胆管癌における血管新生関連分子の発現意義と発がん分子病理機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of gene expression and abnormalities that define clinicopathological features of biliary tract carcinoma and their application in diagnosis and treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of molecular mechanisms involved in carcinogenesis, proliferation and progression of billiary tract carcinoma and its application to clinical treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Synergistic and Pharmacotherapeutic Effects of Gemcitabine and Cisplatin Combined Administration on Biliary Tract Cancer Cell Lines2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PI3K-mTOR pathway identified as a potential therapeutic target in biliary tract cancer using a newly established patient-derived cell panel assay2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 肝胆膵領域に対する病理学的治療効果判定2017

Author(s)

Journal Title

Data Source

[Journal Article] Establishment of various biliary tract carcinoma cell lines and xenograft models for appropriate preclinical studies.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heat Shock Protein 90 Is a Potential Therapeutic Target in Cholangiocarcinoma.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genomic spectra of biliary tract cancer.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] 肝嚢胞性疾患の病理2024

Author(s)

Organizer

Data Source

[Presentation] HILAR CHOLANGIOCARCINOMA WITHOUT MACROSCOPIC MASS FORMATION CLASSIFIED INTO EXTRAHEPATIC CHOLANGIOCARCINOMA BASED ON MOLECULAR PATHOLOGIC STUDIES2023

Author(s)

Organizer

Data Source

[Presentation] 肝臓病理の基礎と診断までのアプローチ2023

Author(s)

Organizer

Data Source

[Presentation] 日本胆道学会認定指導医養成講座 6 胆管内乳頭状腫瘍(IPNB)の基本事項の確認と臨床病理学的意義2022

Author(s)

Organizer

Data Source

[Presentation] Gamma-Synuclein is a novel prognostic marker and promotes tumor cell migration in biliary tract carcinoma.2020

Author(s)

Organizer

Data Source

[Presentation] 病理形態学を基盤とした、胆道悪性腫瘍の進展に関わる分子機構の解明2019

Author(s)

Organizer

Data Source

[Presentation] SYNERGISTIC EFFECTS AND PHARMACOTHERAPEUTIC ACTIVITY OF GEMCITABINE AND CISPLATIN COMBINATION THERAPY IN BILIARY TRACT CANCER CELL LINES2019

Author(s)

Organizer

Data Source

[Presentation] 肝腫瘍の病理と臨床、その基本事項と未来像. ～NASHや糖尿病との関連も含めて～2018

Ojima Hidenori 尾島英知

尾島英知オジマヒデノリ