• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

KAKUMA Tetsuya  加隈 哲也

ORCIDConnect your ORCID iD *help
Researcher Number 80343359
Affiliation (Current) 2022: 大分大学, 保健管理センター, 准教授
Affiliation (based on the past Project Information) *help 2016 – 2021: 大分大学, 保健管理センター, 准教授
2010 – 2015: 大分大学, 医学部, 講師
2014: 大分大学, 医学部内分泌代謝膠原病腎臓内科, 講師
2007 – 2008: Oita University, 医学部, 助教
2003 – 2005: 大分大学, 医学部, 助手
2002: Oita university, department of internal medicine 1, 医学部, 助手
Review Section/Research Field
Principal Investigator
Applied health science / Metabolomics / Gastroenterology / Applied health science / Metabolomics / Basic Section 59040:Nutrition science and health science-related
Except Principal Investigator
Applied health science / Basic Section 59040:Nutrition science and health science-related / Applied health science / Endocrinology / Metabolomics / Environmental physiology (including Physical medicine and Nutritional physiology) / Metabolomics
Keywords
Principal Investigator
インスリン / SREBP / レプチン / 肥満 / 過栄養性脂肪肝 / 炎症性サイトカイン / 脂肪肝 / チアゾリジン誘導体 / PPARγ / 膵β細胞特異的TNFα過剰発現マウス … More / 糖尿病抵抗性 / 肥満抵抗性 / 脂肪肝抵抗性 / グルカゴン / AVP / CRH / UCP / FAS / IRS / 加齢 / 脳内脂質代謝 / 脂質代謝調節 / 脂肪酸組成 / ヒスタミン / アディポネクチン / pleiotropic効果 / Apelin / ピオグリタゾン / db / dbマウス / KKAyマウス / 脾臓摘出 / 脂肪性肝炎 / IL-10 / 摂食リズム障害 / 肥満症 / IL-10欠損マウス / 8オキソグアニン / 機能的グルカゴン低下 / 糖代謝 / 高脂肪食負荷 / 高ショ糖負荷 / 加齢負荷 / ソマトスタチン / TNFα / STZ誘発糖尿病モデル / 交感神経活動 / 神経ヒスタミン / グレリン / AGRP / GLP1 / ストレプトゾトシン誘発インスリン依存性糖尿病モデルラット / 中枢性糖代謝改善 / 糖新生 / 糖利用 / Leptin / Streptozotocin induced diabetes / Sympathetic nerve activity / Neuronal histamine / Ghrelin / 肝臓メタボローム解析 / 脂肪合成低下 / 嫌気性代謝亢進 / アミノ酸代謝亢進 / インスリン分泌 / 迷走神経遮断 / 腸内細菌叢 / Firmicutes / Verrucomicrobia / 臓器間ネットワーク / 食育 / 保健指導 / 行動療法的方法論 / 糖尿病前症 … More
Except Principal Investigator
肥満 / 神経ヒスタミン / 肥満症 / H1受容体 / リズム / エネルギー代謝 / ストレス / 視床下部 / 食行動 / メタボリックシンドローム / 脾臓 / IL-10 / IKBL / HLA / SNP / 糖尿病 / 小腸 / 炎症 / 内分泌学 / エストロゲン / オレキシン / 前頭 / 視交叉上核 / 時計遺伝子 / BMAL-1 / 高脂肪食 / サイトカイン / 肝門脈 / レプチン / 褐色脂肪組織 / アディポネクチン / 交換神経 / 交感神経 / hepatic-portal vein / leptin / feeding behavior / energy metabolism / brown adipose tissue / adiponectin / 膵α細胞 / グルカゴン / 1型糖尿病 / 2型糖尿病 / 抗GAD抗体 / マウス / 膵β細胞 / MIN6 / ゲノム / BRG1 / カルモジュリン / 転写因子 / pancreatic α cell / glucagon / type 1 diabetes mellitus / type 2 diabetes mellitus / anti-GAD antibody / GLP-1 / BDNF / アルツハイマー型認知症 / 脳内BDNF / 認知症 / 認知機能 / サルコペニア / 腸内環境 / マイオカイン / SARS-CoV-2 / ACE2 / 外科療法 / 肥満外科 Less
  • Research Projects

    (19 results)
  • Research Products

    (54 results)
  • Co-Researchers

    (12 People)
  •  肥満に伴う新型コロナウイルス感染の重症化に対するACE2の有用性

    • Principal Investigator
      後藤 孔郎
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Oita University
  •  食育を目指した保健指導への挑戦:行動療法的方法論に基づいた糖尿病前症の対策Principal Investigator

    • Principal Investigator
      加隈 哲也
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Oita University
  •  肥満外科治療による脳内の摂食エネルギー代謝調節因子の解析

    • Principal Investigator
      正木 孝幸
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Oita University
  •  Importance of intestinal environment on the prevention of obesity-induced sarcopenia

    • Principal Investigator
      GOTOH KORO
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Oita University
  •  Examination of cognitive factor in obesity

    • Principal Investigator
      Masaki Takayuki
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Oita University
  •  過栄養性脂肪肝発症における膵臓―脳―肝臓の臓器間ネットワークと腸内細菌叢の関与Principal Investigator

    • Principal Investigator
      加隈 哲也
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Oita University
  •  The role of spleen-derived IL-10 and portal GLP-1 levels in the prevention of obesity-induced dementia

    • Principal Investigator
      Gotoh Koro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Oita University
  •  The relationship between stress-induced hyperphagia and obesity

    • Principal Investigator
      TAKAYUKI MASAKI
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Oita University
  •  The approach for pathogenic mechanism of Type 1 diabetes using transgenic mice expressing TNFalpha selectively in pancreatic beta cellsPrincipal Investigator

    • Principal Investigator
      Kakuma Tetsuya
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Oita University
  •  A novel role for preventing the development of metabolic syndrome

    • Principal Investigator
      GOTOH KORO
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Oita University
  •  The investigation of feeding rhythm and obesity.

    • Principal Investigator
      TAKAYUKI MASAKI
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Oita University
  •  The clarification of pathophysiological mechanism for over-nutritional fatty liver and the involvement of DNA damage by oxygen radicalPrincipal Investigator

    • Principal Investigator
      KAKUMA Tetsuya
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Oita University
  •  ストレスと肥満症:神経ヒスタミンによる脳内メカニズムの解明

    • Principal Investigator
      吉松 博信
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Oita University
  •  Isolation of physiologically active substance regarding the pathogenesis and development of fatty liver under overeatingPrincipal Investigator

    • Principal Investigator
      KAKUMA Tetsuya
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Oita University
  •  Neuronal histamine and H1 receptors regulate biological rhythm and energy metabolism

    • Principal Investigator
      YOSHIMATSU Hironobu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Oita University
  •  The isolation and characterization of anti-diabetic humoral factor mediated by leptin in hypothalamusPrincipal Investigator

    • Principal Investigator
      KAKUMA Tetsuya
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Oita University
  •  脳内SREBPの摂食行動および脂質代謝調節における意義Principal Investigator

    • Principal Investigator
      加隈 哲也
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Metabolomics
    • Research Institution
      大分医科大学
  •  FUNCTION OF NOVEL GENE (BRG1) EXPRESSED IN PANCREATIC BETA CELLS AND IMPLICATION IN PATHOGENESIS OF DIABETES.

    • Principal Investigator
      HAMAGUCHI Kazuyuki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Oita University
      大分医科大学
  •  Hepatic-portal leptin sensor regulates energy metabolism

    • Principal Investigator
      YOSHIMATSU Hironobu
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      OITA MEDICAL UNIVERSITY

All 2020 2019 2018 2017 2016 2015 2013 2012 2011 2008 2007 2006 2005 Other

All Journal Article Presentation

  • [Journal Article] α-Tocopherol suppresses hepatic steatosis by increasing CPT-1 expression in a mouse model of diet-induced nonalcoholic fatty liver disease.2020

    • Author(s)
      Tokoro M, Gotoh K, Kudo Y, Hirashita Y, Iwao M, Arakawa M, Endo M, Oribe J, Masaki T, Honda K, Kakuma T, Seike M, Murakami K, Shibata H.
    • Journal Title

      Obesity Science and Practice

      Volume: 4 Pages: 91-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K01854
  • [Journal Article] α-Tocopherol suppresses hepatic steatosis by increasing CPT-1 expression in a mouse model of diet-induced nonalcoholic fatty liver disease.2020

    • Author(s)
      Tokoro M, Gotoh K, Kudo Y, Hirashita Y, Iwao M, Arakawa M, Endo M, Oribe J, Masaki T, Honda K, Kakuma T, Seike M, Murakami K, Shibata H.
    • Journal Title

      Obes Sci Pract.

      Volume: 7 Pages: 91-99

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K11605
  • [Journal Article] Role of spleen-derived IL-10 in prevention of systemic low-grade inflammation by obesity [Review]2017

    • Author(s)
      Gotoh K, Fujiwara K, Anai M, Okamoto M, Masaki T, Kakuma T, Shibata H.
    • Journal Title

      Endocrine Journal

      Volume: 64 Issue: 4 Pages: 375-378

    • DOI

      10.1507/endocrj.ej17-0060

      10.1507/endocrj.EJ17-0060

    • NAID

      130005630429

    • ISSN
      0918-8959, 1348-4540
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350896
  • [Journal Article] GLP-1 regulates beta-cell mass through brain-derived neurotrophic factor neurons in non-diabetic obese rats.2017

    • Author(s)
      Ando H, Gotoh K, Fujiwara K, Mitsutomi K, Shimasaki T, Itateyama E, Anai M, Chiba S, Masaki T, Seike M, Kakuma T, Shibata H
    • Journal Title

      Scientific Reports

      Volume: 3 Pages: 807-817

    • DOI

      10.1038/s41598-017-05371-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350896
  • [Journal Article] Glucagon-like peptide-1 reduces pancreatic β-cell mass through hypothalamic neural pathways in high-fat diet-induced obese rats.2017

    • Author(s)
      Ando H, Gotoh K, Fujiwara K, Anai M, Chiba S, Masaki T, Kakuma T, Shibata H.
    • Journal Title

      Sci Rep.

      Volume: 7 Pages: 5578-5578

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K01721
  • [Journal Article] Pore alterations of the endothelial lining of rat fenestrated intestinal capillaries exposed to acute stress2016

    • Author(s)
      Aosa T, Chiba S, Kitamura H, Ina K, Tatsukawa S, Moriwaki C, Wei H, Gotoh K, Masaki T, Kakuma T, Shibata H, Fujikura Y
    • Journal Title

      Histol Histopathol

      Volume: 31 Pages: 807-817

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350897
  • [Journal Article] Pore alterations of the endotheliallining of rat fenestrated intestinal capillaries exposed to acute stress.2016

    • Author(s)
      Aosa T, Chiba S, Kitamura H, Ina K, Tatsukawa S, Moriwaki C, Wei H, Gotoh K, Masaki T, Kakuma T, Shibata H, Fujikura Y.
    • Journal Title

      Histol Histopathol.

      Volume: 31 Pages: 807-817

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350896
  • [Journal Article] Fulminant Type 1 Diabetes Mellitus with Anti-programmed Cell Death-1 Therapy2016

    • Author(s)
      Okamoto M, Okamoto M, Gotoh K, Masaki T, Ozeki Y, Ando H, Anai M, Sato A, Yoshida Y, Ueda S, Kakuma T, Shibata H.
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 7 Pages: 915-918

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26350896
  • [Journal Article] Fulminant Type 1 Diabetes Mellitus with Anti-programmed Cell Death-1 Therapy2016

    • Author(s)
      Okamoto M, Okamoto M, Gotoh K, Masaki T, Ozeki Y, Ando H, Anai M, Sato A, Yoshida Y, Ueda S, Kakuma T, Shibata H
    • Journal Title

      J Diabetes Investig

      Volume: 7 Pages: 915-918

    • DOI

      10.1111/jdi.12531

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350897
  • [Journal Article] A clinical approach to brown adipose tissue in the para-aortic area of the human thorax.2015

    • Author(s)
      Wei H, Chiba S, Moriwaki C, Kitamura H, Ina K, Aosa T, Tomonari K, Gotoh K, Masaki T, Katsuragi I, Noguchi H, Kakuma T, Hamaguchi K, Shimada T, Fujikura Y, Shibata H.
    • Journal Title

      PLoS One.

      Volume: 10

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26350896
  • [Journal Article] Obesity-related chronic kidney disease is associated with spleen-derived IL-102013

    • Author(s)
      Gotoh K, Inoue M, Masaki T, Chiba S, Shiraishi K, Shimasaki T, Matsuoka K, Ando H, Fujiwara K, Fukunaga N, Aoki K, Nawata T, Katsuragi I, Kakuma T, Seike M, Yoshimatsu H
    • Journal Title

      Nephrol Dial Transplant

      Volume: 28 Pages: 1120-1130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] Brain-derived neurotrophic factor, corticotropin-releasing factor, and hypothalamic neuronal histamine interact to regulate feeding behavior.2013

    • Author(s)
      Gotoh K, Masaki T, Chiba S, Ando H, Fujiwara K, Shimasaki T, Mitsutomi K, Katsuragi I, Kakuma T, Sakata T, Yoshimatsu H.
    • Journal Title

      J Neurochem.

      Volume: 125 Pages: 588-598

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500845
  • [Journal Article] The dipeptidyl peptidase-4 inhibitor des-fluoro-sitagliptin regulates brown adipose tissue uncoupling protein levels in mice with diet-induced obesity.2013

    • Author(s)
      Shimasaki T, Masaki T, Mitsutomi K, Ueno D, Gotoh K, Chiba S, Kakuma T, Yoshimatsu H.
    • Journal Title

      PLoS One

      Volume: 8

    • DOI

      10.1371/journal.pone.0063626

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] Involvement of remnant spleen volume on the progression of steatohepatitis in diet-induced obese rats after a splenectomy.2012

    • Author(s)
      Inoue M, Gotoh K, Seike M, Masaki T, Oribe J, Honda K, Kakuma T, Yoshimatsu H
    • Journal Title

      Hepatology Research

      Volume: 42 Pages: 203-212

    • NAID

      10031144227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500845
  • [Journal Article] Role of spleen in the development of steatohepatitis in high-fat-diet-induced obese rats2012

    • Author(s)
      Inoue M, Gotoh K, Seike M, Masaki T, Honda K, Kakuma T. Yoshimatsu H
    • Journal Title

      Exp Biol Med

      Volume: 237 Pages: 461-470

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] A novel anti-inflammatory role for spleen-derived interleukin-10 in obesity-induced hypothalamic inflammation.2012

    • Author(s)
      Gotoh K, Inoue M, Masaki T, Chiba S, Shimasaki T, Ando H, Fujiwara K, Katsuragi I, Kakuma T, Seike M, Sakata T, Yoshimatsu H.
    • Journal Title

      Journal of Neurochemistry

      Volume: 120 Pages: 752-764

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500845
  • [Journal Article] Involvement of remnant spleen volume on the progression of steatohepatitis in diet-induced obese rats after a splenectomy.2012

    • Author(s)
      Inoue M, Gotoh K, Seike M, Masaki T, Oribe J, Honda K, Kakuma T, Yoshimatsu H.
    • Journal Title

      Hepatol Res.

      Volume: 42 Pages: 203-212

    • DOI

      10.1111/j.1872-034x.2011.00914.x

    • NAID

      10031144227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] A novel anti-inflammatory role for spleen-derived interleukin-10 in obesity-induced inflammation in white adipose tissue and liver2012

    • Author(s)
      Gotoh K, Inoue M, Masaki T, Chiba S, Shimasaki T, Ando H, Fujiwara K, Katsuragi I, Kakuma T, Seike M, Sakata T, Yoshimatsu H
    • Journal Title

      Diabetes

      Volume: 61 Pages: 1994-2003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] Involvement of remnant spleen volume on the progression of steatohepatitis in diet-induced obese rats after a splenectomy2012

    • Author(s)
      Inoue M, Gotoh K, Seike M, Masaki T, Oribe J, Honda K, Kakuma T. Yoshimatsu H
    • Journal Title

      Hepatol Res

      Volume: 42 Pages: 203-212

    • NAID

      10031144227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] A novel anti-inflammatory role for spleen-derived interleukin-10 in obesity-induced hypothalamic inflammation2012

    • Author(s)
      Gotoh K, Inoue M, Masaki T, Chiba S, Shimasaki T, Ando H, Fujiwara K, Katsuragi I, Kakuma T, Seike M, Sakata T, Yoshimatsu H
    • Journal Title

      J Neurochem

      Volume: 120 Pages: 752-764

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] A Novel Anti-Inflammatory Role for Spleen-Derived Interleukin-10 in Obesity-induced Inflammation in White Adipose Tissue and Liver2012

    • Author(s)
      Gotoh K, Inoue M, Masaki T, Chiba S, Shimasaki T, Ando H, Fujiwara K, Katsuragi I, Kakuma T, Seike M, Sakata T, Yoshimatsu H.
    • Journal Title

      Diabetes

      Volume: 61 Pages: 1994-2003

    • DOI

      10.2337/db11-1688

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] Spleen-derived interleukin-10 downregulates the severity of high-fat diet-induced non-alcoholic Fatty pancreas disease2012

    • Author(s)
      Gotoh K, Inoue M, Shiraishi K, Masaki T, Chiba S, Mitsutomi K, Shimasaki T, Ando H, Fujiwara K, Katsuragi I, Kakuma T, Seike M, Sakata T, Yoshimatsu H
    • Journal Title

      PLoS One

      Volume: 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] Intracerebroventricular administration of urotensin II regulates food intake and sympathetic nerve activity in brown adipose tissue.2012

    • Author(s)
      Yasuda T, Masaki T, Gotoh K, Chiba S, Kakuma T, Yoshimatsu H.
    • Journal Title

      Peptides.

      Volume: 35 Pages: 131-135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500845
  • [Journal Article] Intraperitoneal administrartion attenuates thiazolidinedions-induced hepatic steatosis in KKAy mice with increased hepatic peroxisome proliferator-activated receptor (PPAR)γ mRNA expression2012

    • Author(s)
      Oribe J, Kakuma T, Haranaka M, Okamoto K, Seike M, Yoshimatsu H
    • Journal Title

      Obes Res Clin Prac

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] Ghrelin in small intestine, its contribution to regulation of food intake and body weight in cross-intestinal parabiotic rats.2011

    • Author(s)
      Noguchi H, Masaki T, Kakuma T, Nakazato M, Yoshimatsu H
    • Journal Title

      Endocrine Journal

      Volume: 58 Pages: 625-632

    • NAID

      10029589582

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500845
  • [Journal Article] Effects of Pravastatin on Obesity, Diabetes, and Adiponectin in Diet-induced Obese Mice2008

    • Author(s)
      Araki K, Masaki T, Katsuragi I, Kakuma T, Yoshimatsu H.
    • Journal Title

      Obesity (Silver Spring)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Journal Article] Effects of pravastatin on obesity, diabetes, and adiponectin in diet-induced obese mice2008

    • Author(s)
      Araki K, Masaki T, Katsuragi I, Kakuma T, Yoshimatsu H.
    • Journal Title

      Obesity (SilverSpring) 16(9)

      Pages: 2068-2073

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Journal Article] Apelin, an APJ receptor ligand, regulates body adiposity and favors the messenger ribonucleic acid expression of uncoupling proteins in mice2007

    • Author(s)
      Higuchi K, Masaki T, Gotoh K, Chiba S, Katsuragi I, Tanaka K, Kakuma T, Yoshimatsu H.
    • Journal Title

      Endocrinology 148(6)

      Pages: 2690-2697

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Journal Article] Apelin, an APJ receptor ligand, regulates body adiposity and favors the messenger ribonucleic acid expression of uncoupling proteins in mice2007

    • Author(s)
      Higuchi K, Masaki T, Gotoh K, Chiba S, Katsuragi I, Tanaka K, Kakuma T, Yoshimatsu H.
    • Journal Title

      Endocrinology 148

      Pages: 2690-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Journal Article] Hypothalamic neuronal histamine mediates the thyrotropin-releasing hormone-induced suppression of food intake2007

    • Author(s)
      Gotoh K, Fukagawa K, Fukagawa T, Noguchi H, Kakuma T, Sakata T, Yoshimatsu H.
    • Journal Title

      J Neurochem 103(3)

      Pages: 1102-1110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Journal Article] Hypothalamic neuronal histamine mediates the thyrotropin-releasing hormone-induced suppression of food intake2007

    • Author(s)
      Gotoh K, Fukagawa K, Fukagawa T, Noguchi H, Kakuma T, Sakata T, Yoshimatsu H.
    • Journal Title

      J Neurochem 103

      Pages: 1102-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Journal Article] Sterol regulatory element binding protein(SREBP)-1 expression in brain is affected by age but not by hormones or metabolic changes2006

    • Author(s)
      Okamoto K, Kakuma T, Fukuchi S, Masaki T, Sakata T, Yoshimatsu H.
    • Journal Title

      Brain Res. 1081(1)

      Pages: 19-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Journal Article] Telmisartan prevents obesity and increases the expression of uncoupling protein 1 in diet-induced obese mice2006

    • Author(s)
      Araki K, Masaki T, Katsuragi I, Tanaka K, Kakuma T, Yoshimatsu H.
    • Journal Title

      Hypertension 48(1)

      Pages: 51-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Journal Article] The role of histamine H1 receptor and H2 receptor in LPS-induced liver injury2005

    • Author(s)
      Masaki T, Chiba S, Tatsukawa H, Noguchi H, Kakuma T, Endo M, Seike M, Watanabe T, Yoshimatsu H.
    • Journal Title

      FASEB J. 19(10)

      Pages: 1245-1252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Presentation] 脳―脾連関からみた肥満による全身性慢性炎症の発症メカニズム2020

    • Author(s)
      後藤孔郎,吉田雄一,尾関良則,野口貴昭、松田直樹、木下みずき、渋田可奈子、宮本昇太郎、穴井学,岡本光弘, 正木孝幸,加隈哲也,柴田洋孝孝
    • Organizer
      第93回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K11605
  • [Presentation] 脳ー脾相関からみた肥満による全身性慢性炎症の発症メカニズム2020

    • Author(s)
      後藤孔郎、吉田雄一、尾関良則、穴井学、岡本光弘、正木孝幸、加隈哲也、柴田洋孝
    • Organizer
      第93回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K01855
  • [Presentation] 糖尿病抵抗性、肥満抵抗性、脂肪肝抵抗性マウスの腸内細菌叢と肝臓メタボローム解析2019

    • Author(s)
      加隈哲也、藤原貫爲、酒井久美子、千葉政一、後藤孔郎、正木孝幸、柴田洋孝、吉村充弘、上田陽一
    • Organizer
      第92回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K01855
  • [Presentation] 膵β細胞特異的TNFα過剰発現マウスは糖尿病抵抗性、肥満抵抗性、脂肪肝抵抗性を呈する2018

    • Author(s)
      加隈哲也、藤原貫爲、安藤久恵、千葉政一、後藤孔郎、正木孝幸、柴田洋孝、吉村充弘、上田陽一
    • Organizer
      第91回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K01855
  • [Presentation] グルカゴン分泌調節におけるGLP-1と脳由来神経栄養因子との関連2018

    • Author(s)
      後藤孔郎、吉田雄一、尾関良則、岡本将英、岡本光弘、正木孝幸、加隈哲也、柴田洋孝
    • Organizer
      第39回日本肥満学会
    • Data Source
      KAKENHI-PROJECT-17K01854
  • [Presentation] 肥満による代償性膵島過形成に対するGLP-1の中枢神経を介した改善作用2018

    • Author(s)
      後藤孔郎、安藤久恵、吉田雄一、尾関良則、岡本将英、穴井学、岡本光弘、正木孝幸、加隈哲也、柴田洋孝
    • Organizer
      第91回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K01854
  • [Presentation] 膵β細胞特異的TNFα過剰発現マウスは糖尿病抵抗性、肥満抵抗性、脂肪肝抵抗性を呈する2017

    • Author(s)
      加隈哲也、藤原貫爲、安藤久恵、千葉政一、後藤孔郎、正木孝幸、柴田洋孝、吉村充弘、上田陽一
    • Organizer
      第38回日本肥満学会
    • Data Source
      KAKENHI-PROJECT-17K01855
  • [Presentation] リラグルチドからリキシセナチドへの変更の有効性をアセトアミノフェン試験で確認し得た2 型糖尿病の一例2017

    • Author(s)
      森優美,富本あけみ,岡本将英,岡本光弘,仲間寛,野口貴昭,福山光,後藤孔郎,正木孝幸,加隈哲也,柴田洋孝
    • Organizer
      第60回日本糖尿病学会年次総会
    • Data Source
      KAKENHI-PROJECT-26350896
  • [Presentation] 肥満「症」としての2型糖尿病ー最近の話題と課題ー2016

    • Author(s)
      加隈哲也
    • Organizer
      第54回日本糖尿病学会九州地方会
    • Place of Presentation
      鹿児島
    • Year and Date
      2016-10-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-26350897
  • [Presentation] 肥満に伴う肝臓や内臓脂肪内の炎症性変化およびインスリン抵抗性における、脾臓由来IL-10の役割2015

    • Author(s)
      後藤 孔郎, 正木 孝幸, 加隈 哲也, 柴田 洋孝
    • Organizer
      第2回肝臓と糖尿病・代謝研究会
    • Place of Presentation
      海峡メッセ下関(山口県下関市)
    • Year and Date
      2015-05-23
    • Data Source
      KAKENHI-PROJECT-24500859
  • [Presentation] 肥満に伴う肝の脂肪化, 炎症性変化およびインスリン抵抗性における脾臓の役割2013

    • Author(s)
      後藤孔郎, 井上恵, 白石賢太郎, 安藤久恵, 嶋崎貴信, 正木孝幸, 千葉政一, 藤原貫為, 清家正隆, 加隈哲也
    • Organizer
      第86回日本内分泌学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Presentation] 肥満に伴う非アルコール性脂肪性肝疾患(NAFLD)の発症における脾臓由来IL-10の役割2013

    • Author(s)
      後藤孔郎, 正木孝幸, 千葉政一, 嶋崎貴信, 安藤久恵, 藤原貫為, 加隈哲也, 清家正隆, 柴田洋孝
    • Organizer
      第34回日本肥満学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Presentation] 2型糖尿病治療における血糖と体重の良好なコントロールの両立を目指して2013

    • Author(s)
      加隈哲也
    • Organizer
      第51回日本糖尿病学会九州地方会
    • Place of Presentation
      那覇
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Presentation] 中枢性因子と食行動2013

    • Author(s)
      加隈哲也
    • Organizer
      第34回日本肥満学会(シンポジウム)
    • Place of Presentation
      東京国際フォーラム(東京都千代田区)
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Presentation] 肥満に伴う視床下部内の慢性炎症における脾臓由来IL-10の役割2012

    • Author(s)
      後藤孔郎, 井上恵, 正木孝幸, 千葉政一, 嶋崎貴信, 安藤久恵, 藤原貫為, 葛城功, 加隈哲也, 清家正隆, 坂田利家, 吉松博信
    • Organizer
      第55回日本糖尿病学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Presentation] 肥満糖尿病マウスにおいてチアゾリジン誘導体による脂肪肝増悪の機序2008

    • Author(s)
      織部淳哉、清家正隆、加隈哲也、原中美環、岡本健二郎、吉松博信
    • Organizer
      第44回日本肝臓学会総会
    • Place of Presentation
      愛媛
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Presentation] 肥満糖尿病マウスにおけるチアゾリジン誘導体の肝臓、代謝への影響2007

    • Author(s)
      織部淳哉、清家正隆、加隈哲也、荒川光江、遠藤美月、吉松博信
    • Organizer
      第43回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Presentation] 糖尿病合併脂肪肝症例と非脂肪肝症例の予後の検討2007

    • Author(s)
      織部淳哉、清家正隆、針里栄、井上恵、姫野克郎、高橋祐幸、加隈哲也、吉松博信
    • Organizer
      第93回日本消化器病学会総会
    • Place of Presentation
      青森
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Presentation] 肥満に伴う非アルコール性脂肪性膵疾患(NAFPD)における脾臓由来IL-10の役割

    • Author(s)
      後藤 孔郎, 正木 孝幸, 加隈 哲也, 柴田 洋孝
    • Organizer
      第58回日本糖尿病学会総会
    • Place of Presentation
      海峡メッセ下関(山口県下関市)
    • Year and Date
      2015-05-21 – 2015-05-23
    • Data Source
      KAKENHI-PROJECT-24500859
  • [Presentation] 肥満に伴う非アルコール性脂肪性膵疾患(NAFPD)における脾臓由来IL-10の役割

    • Author(s)
      後藤 孔郎, 正木 孝幸, 加隈 哲也, 柴田 洋孝
    • Organizer
      第88回日本内分泌学会総会
    • Place of Presentation
      ホテルニューオータニ東京(東京都千代田区)
    • Year and Date
      2015-04-22 – 2015-04-24
    • Data Source
      KAKENHI-PROJECT-24500859
  • 1.  TAKAYUKI MASAKI (00423715)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 38 results
  • 2.  GOTO Koro (10457624)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 25 results
  • 3.  YOSHIMATSU Hironobu (00166993)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 28 results
  • 4.  柴田 洋孝 (20245484)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 14 results
  • 5.  SEIKE Masataka (40253794)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 18 results
  • 6.  CHIBA Seiichi (20457633)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 7.  岡本 光弘 (80774546)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  HAMAGUCHI Kazuyuki (60180931)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  INA Keisuke (20203193)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  WAKANA Sigeharu (90192434)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  坂田 利家 (50037420)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  植田 聡 (00624511)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

URL: 

Are you sure that you want to connect your ORCID iD to this researcher?
* This action can be performed only by the researcher themselves.

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi