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TAKABATAKE Noriaki  高畠 典明

ORCIDConnect your ORCID iD *help
Researcher Number 80344795
Affiliation (based on the past Project Information) *help 2007 – 2008: Yamagata University, School of Medicine, Lecturer
2003 – 2006: 山形大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Respiratory organ internal medicine
Except Principal Investigator
Respiratory organ internal medicine
Keywords
Principal Investigator
COPD / IPF / Endothelial Injury / 慢性閉塞性肺疾患 / 肺毛細血管内皮細胞機能障害 / 突発性肺線維症 / 123 I-MIBG肺シンチグラム / 喫煙 / SNP / PLA2 … More / 体重減少 / 肺毛細血管内皮機能障害 / 洗い出し率 / Iodine-123-Metaiodobenzylguanidine / 肺毛細血管内皮細胞の障害 / ^<123>I-MIBGシンチグラム … More
Except Principal Investigator
MafB / metastasis / lung adenocarcinoma / integrin / invasion / clarithromycin / lung cancer / thymidine phosphorylase / pulmonary emphysema / cigarette smoking / transcription factor / alveolar macrophage / 肺気腫 / 喫煙 / 転写因子 / 肺胞マクロファージ / 肺胞マクロフィージ / clearthromycin / clarithromycin (CAM) / invasiveness / thymidine phosphorylase (TP) / Clarithromycin / Thymidine phosphorylase Less
  • Research Projects

    (7 results)
  • Research Products

    (37 results)
  • Co-Researchers

    (10 People)
  •  Research for the mechanism of the body weight loss in patients with chronic obstructive pulmonary diseasePrincipal Investigator

    • Principal Investigator
      TAKABATAKE Noriaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Yamagata University
  •  Assessment for the mechanisms of anti-apoptotic effects of transcription factor MafB in alveolar macrophages of emphysematous lungs induced by cigarette smoke exposure

    • Principal Investigator
      SHIBATA Yoko
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Yamagata University
  •  The significance of endothelial cell dysfunction in pulmonary microvessels in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosisPrincipal Investigator

    • Principal Investigator
      TAKABATAKE Noriaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Yamagata University
  •  Role of thymidine phosphorylase on invasive potential in lung adenocarcinoma

    • Principal Investigator
      SATA Makoto
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      National Cardiovascular Center Research Institute
      Yamagata University
  •  Role of transcription factor MafB in alveolar macrophages of smoking-induced emphysema

    • Principal Investigator
      SHIBATA Yoko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Yamagata University
  •  慢性閉塞性肺疾患の新たな発症機序の解明:肺毛細血管内皮細胞機能障害の関与Principal Investigator

    • Principal Investigator
      高畠 典明
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Yamagata University
  •  Roles of thymidine phosphorylase on invasiveness and metastasis in lung cancer

    • Principal Investigator
      SATA Makoto
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Yamagata University

All 2008 2007 2006 2005 2003 Other

All Journal Article Presentation

  • [Journal Article] A nonfunctioning single nucleotide polymorphism in olfactory receptor gene fanily is associated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population2007

    • Author(s)
      Takabatake, N, et. al.
    • Journal Title

      Biochem Biophys Res Commun 364.3

      Pages: 662-667

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590835
  • [Journal Article] Anonfunctioning single nucleotide polymorphism in olfactory receptor gene family is associated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population2007

    • Author(s)
      Takabatake N, et. al.
    • Journal Title

      Biochem Biophys Res Commun 364.3

      Pages: 662-667

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590835
  • [Journal Article] A nonfunctioning single nucleotide polymorphism in olfactory receptor gene family isassociated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population2007

    • Author(s)
      Takabatake N, et. al.
    • Journal Title

      Biochem Biophys Res Commun 364.3

      Pages: 662-667

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590880
  • [Journal Article] A nonfunctioning single nucleotide polymorphism in olfactory receptor gene family is associated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population2007

    • Author(s)
      Takabatake N., et. al.
    • Journal Title

      Biochem Biophys Res Commun 364

      Pages: 662-667

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590835
  • [Journal Article] Enhanced expression of MafB inhibits macrophage apoptosis induced by cigarette smoke exposure.2007

    • Author(s)
      Machiya J, Shibata Y, Yamauchi K, Hirama N, Wada T, Inoue S, Abe S, Takabatake N, Sata M, Kubota I
    • Journal Title

      Am J Respir Cell Mol Biol 36

      Pages: 418-426

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Increased surfactant protein-D and foamy alveolar macrophages in smoking-induced mouse emphysema.2007

    • Author(s)
      Hirama N, Shibata Y, Otake K, Machiya J, Wada T, Inoue S, Abe S, Takabatake N, Sata M, Kubota I
    • Journal Title

      Respirology 12

      Pages: 191-201

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Intronic single-nucleotide polymorphisms in Bcl-2 are associated with chronic obstructive pulmonary disease severity.2007

    • Author(s)
      Sata M, Takabatake N, Inoue S, Shibata Y, Abe S, Machiya J, Wada T, Ji G, Kido T, Matsuura T, Muramatsu M, Kubota I
    • Journal Title

      Respirology 12

      Pages: 34-41

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Clarithromycin suppresses invasiveness of human lung adenocarcinoma cells.2007

    • Author(s)
      Wada T, Sata M, Sato J, Tokairin Y, Machiya J, Hirama N, Arao T, Inoue S, Takabatake N, Shibata Y, Kubota I
    • Journal Title

      Chemotherapy 53

      Pages: 77-84

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] A single polymorphism in CCL1 gene predicts acute exacerbations in COPD.2006

    • Author(s)
      Takabatake N, Shibata Y, Abe S, Wada T, Machiya J, Igarashi A, Tokairin Y, Ji G, Sato H, Sata M, Takeishi Y, Emi M, Muramatsu M, Kubota I
    • Journal Title

      Am J Respir Crit Care Med 174

      Pages: 875-885

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] A single nucleotide polymorphism in the CCL1 gene predicts acute exacerbations in chronic obstructive pulmonary disease.2006

    • Author(s)
      Takabatake N. et al.
    • Journal Title

      Am J Respir Crit Care Med. 174

      Pages: 875-885

    • Data Source
      KAKENHI-PROJECT-17590778
  • [Journal Article] A single nucleotide polymorphism in the CCL1 gene predicts acute exacerbations in chronic obstructive pulmonary disease.2006

    • Author(s)
      Takabatake N. et al.
    • Journal Title

      Am J Respir Crit Care Med 174

      Pages: 875-885

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590778
  • [Journal Article] A single nucleotide polymorphism in the CCL1 gene predicts acute exacerbations in chronic obstructive pulmonary disease2006

    • Author(s)
      Takabatake N. et al.
    • Journal Title

      Am J Respir Crit Care Med. 174

      Pages: 875-885

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590778
  • [Journal Article] A single polymorphism in CCL1 gene predicts acute exacerbations in COPD2006

    • Author(s)
      Takabatake N, et al.
    • Journal Title

      Am J Respir Crit Care Med 174

      Pages: 875-885

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Impaired Systemic Cell-Mediated Immunity and Increased Susceptibility to Acute Respiratory Tract Infections in Patients with COPD2005

    • Author(s)
      Takabatake N, Sata M, et al.
    • Journal Title

      Respir Med 99

      Pages: 485-492

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] A Novel Polymorphism in Secretory Phospholipase A_2 IID is Associated with Body Weight Loss in COPD.2005

    • Author(s)
      Takabatake N, Sata M, et al.
    • Journal Title

      Am J Respir Crit Care Med 172

      Pages: 1097-1104

    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Impaired systemic cell-mediated immunity and increased susceptibility to acute respiratory tract infections in patients with COPD.2005

    • Author(s)
      Takabatake N, Sata M, Abe S, Inoue S, Saito H, Yuki H, Shibata Y, Kubota I
    • Journal Title

      Resp Med 99

      Pages: 485-492

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] Involvement of pulmonary endothelial cell injury in the pathogenesis of pulmonary fibrosis : clinical assessment by ^<123>I-MIBG lung scintigraphy.2005

    • Author(s)
      Takabatake N, Arao T, Sata M, Abe S, Inoue S, Shibata Y, Takeishi Y, Kubota I
    • Journal Title

      Eur J Nucl Med Imaging 32

      Pages: 221-228

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] Circulating levels of soluble Fas ligand in cachexic patients with COPD are higher than those in non-cachexic patients with COPD.2005

    • Author(s)
      Takabatake N, Arao T, Sata M, Inoue S, Abe S, Shibata Y, Kubota I
    • Journal Title

      Intern Med 44

      Pages: 1137-1143

    • NAID

      10016885943

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Impaired systemic cell-mediated immunity and increased susceptibility to acute respiratorv tract infections in patients with COPD.2005

    • Author(s)
      Takabatake N.et al.
    • Journal Title

      Respir Med 99

      Pages: 485-492

    • Data Source
      KAKENHI-PROJECT-17590778
  • [Journal Article] A novel polymorphism in secretory phospholipase A_2-IID is : associated with body weight loss in COPD.2005

    • Author(s)
      Takabatake N, Sata M, Inoue S, Shibata Y, Abe S, Wada T, Machiya J, Ji G, Matsuura T, Takeishi Y, Muramatsu M, Kubota I
    • Journal Title

      Am J Respir Crit Care Med 172 (Originally published in press as DOI:10.1164/rccm.200503-3190C on July 7 2005)

      Pages: 1097-1104

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Circulating levels of soluble Fas ligand in cachexic patients with COPD are higher than those in non-cachexic patients with COPD2005

    • Author(s)
      Takabatake N.et al.
    • Journal Title

      Intern Med. 44

      Pages: 1137-1143

    • NAID

      10016885943

    • Data Source
      KAKENHI-PROJECT-17590778
  • [Journal Article] Involvement of pulmonary endothelial cell injury in the pathogenesis of pulmonary fibrosis : clinical assessment by 123I-MIBG lung scintigraphy2005

    • Author(s)
      Takabatake N, Arao T, Sata M, et al.
    • Journal Title

      European Journal of Nuclear Medicine and Molecular Imaging 32

      Pages: 221-228

    • Data Source
      KAKENHI-PROJECT-15790407
  • [Journal Article] Involvement of pulmonary endothelial cell injury in the pathogenesis of pulmonary fibrosis : clinical assessment by ^<123>I-MIBG lung scintigraphy.2005

    • Author(s)
      Takabatake N, Arao T, Sata M, Abe S, Inoue S, Shibata Y, Honma T, Takahashi K, Okada A, Takeishi Y, Kubota I
    • Journal Title

      Eur J Nucl Med Mol Imaging 32

      Pages: 221-228

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] Involvement of pulmonary endothelial cell injury in the pathogenesis of pulmonary fibrosis : clinical assessment by ^<123>I-MIBG lung scintigraphy2005

    • Author(s)
      Takabatake N, Arao T, Sata M, et al.
    • Journal Title

      Eur J Nucl Med Mol Imaging 32

      Pages: 221-228

    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] Impaired systemic cell-mediated immunity and increased susceptibility to acute respiratory tract infections in patients with COPD.2005

    • Author(s)
      Takabatake N, Sata M, Abe S, Inoue S, Saito H, Yuki H, Shibata Y, Kubota I
    • Journal Title

      Respir Med 99

      Pages: 485-492

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590779
  • [Journal Article] In vivo evidence of endothelial injury in chronic obstructive pulmonary disease by lung scintigraphic assessment of (123)I-metaiodobenzylguanidine.2003

    • Author(s)
      Arao T, Takabatake N, Sata M, et al.
    • Journal Title

      Journal of Nuclear Medicine 44

      Pages: 1747-1754

    • Data Source
      KAKENHI-PROJECT-15790407
  • [Journal Article] Role of thymidine phosphorylase on invasiveness and metastasis in lung adenocarcinoma.2003

    • Author(s)
      Sato J, Sata M, Nakamura H, Inoue S, Wada T, Takabatake N, Otake K, Tomoike H, Kubota I
    • Journal Title

      Int J Cancer 106

      Pages: 863-870

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] In vivo evidence of endothelial injury in chronic obstructive pulmonary disease by lung scintigraphic assessment of ^<123>I-metaiodobenzylguanidine2003

    • Author(s)
      Arao T, Takabatake N, Sata M, et al.
    • Journal Title

      J Nucl Med 44

      Pages: 1747-1754

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] In vivo evidence of endothelial injury in chronic obstructive pulmonary disease by lung scintigraphic assessment of ^<123>I-metaiodobenzylguanidine.2003

    • Author(s)
      Arao T, Takabatake N, Sata M, Abe S, Shibata Y, Honma T, Takahashi K, Okada A, Takeishi Y, Kubota I
    • Journal Title

      J Nucl Med 44

      Pages: 1747-1754

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590796
  • [Journal Article] Gly80Ser Polymorphism of Phospholipase A2-IID Is Associated with Cytokine Inducibility in A549 Cells

    • Author(s)
      Igarashi A, Shibata Y, Yamauchi K, Osaka D, Takabatake N et.al.
    • Journal Title

      2009 Respiration (In Press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590880
  • [Journal Article] Altered expression of antimicrobial molecules in cigarette smoke-exposed emphysematous mice lungs

    • Author(s)
      Shibata Y, Abe S, Inoue S, Takabatake N et.al.
    • Journal Title

      2008 Respirology 13

      Pages: 1061-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590880
  • [Presentation] 肺細胞における分泌型ホスホリパーゼA2-IIDの第80番目のアミノ酸多型とサイトカイン誘導能との関係2008

    • Author(s)
      五十嵐朗、柴田陽光、高畠典明ら
    • Organizer
      第48回日本呼吸器学会学術講演会
    • Place of Presentation
      神戸
    • Year and Date
      2008-06-15
    • Data Source
      KAKENHI-PROJECT-19590880
  • [Presentation] A Novel Polytnorphisrn in Secretory Phosphetipase A 2-llD ls Associated with Body Weight Loss in Chronic Obstructive Pulmonary Disease2007

    • Author(s)
      Takabatake, N., et. al.
    • Organizer
      ATS 2007 San Francisco
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2007-05-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590835
  • [Presentation] A Novel Polymorphism in Secretory Phospholipase A 2-llD Is Associated with Body Weight Loss in Chronic Obstructive Pulmonary Disease2007

    • Author(s)
      Takabatake N., et. al.
    • Organizer
      ATS 2007 San Francisco
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2007-05-22
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590835
  • [Presentation] A Single Nucleotide Polymorphism in CCL1 Gene Predicts Acute Exacerbaions in Chronic Obstructive Pulmonary Disease2007

    • Author(s)
      Takabatake, N., et. al.
    • Organizer
      ATS 2007 San Francisco
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2007-05-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590835
  • [Presentation] A novel polymorphism in secretory phospholipase A2-IID is associated with body weight loss in chronic obstructive pulmonary disease2007

    • Author(s)
      Takabatake N., et. al.
    • Organizer
      ATS 2007 San Francisco
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2007-05-22
    • Data Source
      KAKENHI-PROJECT-19590880
  • [Presentation] A Single Nucleotide Polymorphism in CCL1 Gene Predicts Acute Exacerbations in Chronic Obstructive Pulmonary Disease2007

    • Author(s)
      Takabatake N., et. al.
    • Organizer
      ATS 2007 San Francisco
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2007-05-22
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590835
  • 1.  SHIBATA Yoko (60333978)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 12 results
  • 2.  SATA Makoto (00280892)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 17 results
  • 3.  NITOBE Joji (30400542)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  TAKASAKI Satoshi (20400541)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MIYAMOTO Takuya (20447204)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  TAKEISHI Yasuchika (40272067)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  ABE Shuichi (40400543)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  IGARASHI Akira
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  KIMURA Tomomi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  OSAKA Daisuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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