Kakizaki Satoru 柿崎暁

… Alternative Names

KAKIZAKI Satoru 柿崎暁

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Researcher Number	80344935
Other IDs
Affiliation (Current)	2025: 独立行政法人国立病院機構高崎総合医療センター(臨床研究部), 臨床研究部, 臨床研究部長 2025: 群馬大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 独立行政法人国立病院機構高崎総合医療センター(臨床研究部), 臨床研究部, 臨床研究部長 2016 – 2023: 群馬大学, 大学院医学系研究科, 講師 2020: 群馬大学, 大学院医学系研究科, 客員教授 2014 – 2015: 群馬大学, 医学(系)研究科(研究院), 講師 2013: 群馬大学, 医学部附属病院, 助教 2007 – 2012: Gunma University, School of Medicine, Associate professor 2003 – 2006: 群馬大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 56030:Urology-related / Environmental and hygienic pharmacy Except Principal Investigator Gastroenterology / Basic Section 47060:Clinical pharmacy-related / Basic Section 49030:Experimental pathology-related / Basic Section 53010:Gastroenterology-related / Experimental pathology / Pediatric surgery
Keywords	Principal Investigator CAR / 核内レセプター / cytochrome P450 / 核内受容体 / ＣＡＲ / PXR / 非アルコール性脂肪性肝炎 / リン酸化核内受容体 / 前立腺癌 / アンドロゲン受容体 … More / 肝内胆管癌 / 化学発癌 / 胆管癌 / Nuclear receptor / Non alcoholic steatohepatitis / 非アルコール性脂防性肝炎 / DSS腸炎 / 炎症性サイトカイン / ＤＳＳ腸炎 / ＰＸＲ / 炎症性腸疾患 / Ctochrome P450 / 肝線維化 / Cytochrome P450 / 薬物代謝酵素 / 肝内胆汁鬱滞 / 薬剤性肝障害 … More Except Principal Investigator 核内受容体 / NASH / 脂肪肝 / 非アルコール性脂肪性肝炎 / 核内受容体CAR / 脂肪酸 / マクロファージ遊走阻止因子 / 肝癌 / 線維化 / MIF / 肝前駆細胞 / アジア人 / 肝星細胞 / PXR / 上皮間葉転換 / 肝がん / サルコペニア / 加齢 / 薬物代謝 / 肝疾患 / 胆管障害 / dysbiosis / 腸内フローラ / 次世代影響 / 発達毒性 / 新生仔 / CAR / 遺伝子発現 / 成長障害 / 薬物代謝酵素 / 甲状腺ホルモン / 肝臓 / 化学物質 / miRNA / 繊維化 / 胆管再生 / 胆管形成 / 胆管上皮細胞増殖 / CD74 / ＭＩＦ / 非アルコール性脂肪性肝炎（ＮＡＳＨ） / マクロファージ遊走阻止因子（ＭＩＦ） / 脂肪性肝炎 / アルコール / メタボリック症候群 / 肝発癌 / マクロファージ / NASH(非アルコール性脂肪性肝炎） / MIF(マクロファージ遊走阻止因子） / 遺伝子 / 応用動物 / HNF4α / マウスモデル / ＭＩＦ（マクロファージ遊走阻止因子） / 肝腫瘍 / NASH　非アルコール性脂肪性肝炎 / MIF マクロファージ遊走阻止因子 / 高脂肪食 / 脂質沈着 / 肝線維化 / 肝再生 / オーバル細胞増殖 / トランスジェニックマウス / ノックアウトマウス / 癌抑制遺伝子 / 横紋筋肉腫 Less

Development of a Treatment Strategy for Hepatocellular CarcinomaThorough Nuclear Receptor PXR-Mediated Inhibition of Epithelial-Mesenchymal Transition
- Principal Investigator
  
  志津怜太
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  University of Shizuoka
前立腺癌の去勢抵抗性獲得メカニズムとリン酸化核内受容体の病態解明Principal Investigator
- Principal Investigator
  
  柿崎暁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  独立行政法人国立病院機構高崎総合医療センター(臨床研究部)
核内受容体による痩せ型の非アルコール性脂肪肝炎の発症・進行機構の解明
- Principal Investigator
  
  井上裕介
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Gunma University
Development of a drug metabolism capacity and interaction evaluation system for the elderly with sarcopenia and avoidance of adverse drug reaction risks.
- Principal Investigator
  
  戸島洋貴
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Gunma University
Investigation of the next-generation and late-onset effects of drugs focusing on liver maturation and liver function regulated by the nuclear receptors PXR and CAR
- Principal Investigator
  
  Yoshinari Kouichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  University of Shizuoka
腸内フローラの破綻時の胆管障害における核内受容体CAR/PXRの役割
- Principal Investigator
  
  山崎勇一
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Gunma University
Mechanism of NASH pathogenesis by nuclear receptors through qualitative changes in fatty acids
- Principal Investigator
  
  Inoue Yusuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Gunma University
The role of nuclear receptor CAR in the pathogenesis of intrahepatic cholangiocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  Kakizaki Satoru
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  Gunma University
The role of nuclear receptor CAR in hepatic progenitor cell-mediated bile duct epithelial cell proliferation, bile duct formation and regeneration
- Principal Investigator
  
  Yamazaki Yuichi
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Gunma University
Basic research of the developmental mechanism and the therapeutic application of NASH by HNF4a and PPARa
- Principal Investigator
  
  Inoue Yusuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Gunma University
Disecting the role of MIF-CD74 signaling on hepatocarcinogenesis
- Principal Investigator
  
  HORIGUCHI NORIO
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Gunma University
The role of nuclear receptors PXR/CAR in the pathogenesis of inflammatory bowel diseases.Principal Investigator
- Principal Investigator
  
  Kakizaki Satoru
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Gunma University
The role of macrophage inhibitory factor (MIF) in NASH
- Principal Investigator
  
  HORIGUCHI NORIO
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Gunma University
The role of nuclear receptor CAR in the liver regeneration and repair madiated by oval cell proliferation.
- Principal Investigator
  
  Yamazaki Yuichi
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Gunma University
肝細胞増殖因子トランスジェニックマウスを用いた横紋筋肉腫発癌機序の解析
- Principal Investigator
  
  市川武
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Gunma University
The role and crosstalk between nuclear receptors PXR and CAR on the pathogenesis of non-alcoholic steatohepatitis.Principal Investigator
- Principal Investigator
  
  KAKIZAKI Satoru
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Gunma University
The role of nuclear receptor CAR in the pathogenesis of non-alcoholic SteatohepatitisPrincipal Investigator
- Principal Investigator
  
  KAKIZAKI Satoru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Gunma University
薬剤性肝障害、肝内胆汁鬱滞症における核内オーファンレセプターCARの役割Principal Investigator
- Principal Investigator
  
  柿崎暁
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Gunma University

[Book] Vitamin E and liver diseases. In"Vitamin E;New research."2006
- Author(s)
  Kakizaki S, et. al.
- Total Pages
  211
- Publisher
  Nova Science Publishers, Inc.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] The influence of the long‐term chemical activation of the nuclear receptor pregnane X receptor (PXR) on liver carcinogenesis in mice2021
- Author(s)
  Ryota Shizu, Mai Ishimura, Sumihito Nobusawa, Takuomi Hosaka, Takamitsu Sasaki, Satoru Kakizaki, Kouichi Yoshinari
- Journal Title
  
  Archives of Toxicology
  
  Volume: 95 Issue: 3 Pages: 1089-1102
- DOI
  10.1007/s00204-020-02955-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07202, KAKENHI-PROJECT-17K08387, KAKENHI-PROJECT-19K16352
[Journal Article] Lenvatinib for Hepatocellular Carcinoma: A Literature Review2021
- Author(s)
  Hatanaka Takeshi、Naganuma Atsushi、Kakizaki Satoru
- Journal Title
  
  Pharmaceuticals
  
  Volume: 14 Issue: 1 Pages: 36-36
- DOI
  10.3390/ph14010036
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08387
[Journal Article] Analyses of objective response rate, progression-free survival, and adverse events in hepatocellular carcinoma patients treated with lenvatinib: A multicenter retrospective study.2020
- Author(s)
  Hatanaka T, Kakizaki S, Nagashima T, Namikawa M, Tojima H, Shimada Y, Takizawa D, Naganuma A, Arai H, Sato K, Harimoto N, Shirabe K, Uraoka T.
- Journal Title
  
  Hepatol Res.
  
  Volume: 50 Issue: 3 Pages: 382-395
- DOI
  10.1111/hepr.13460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08387
[Journal Article] Long-term Results of Bariatric Surgery for Non-alcoholic Fatty Liver Disease/Non-alcoholic Steatohepatitis Treatment in Morbidly Obese Japanese Patients.2019
- Author(s)
  Uehara D, Seki Y, Kakizaki S, Horiguchi N, Tojima H, Yamazaki Y, Sato K, Yamada M, Uraoka T, Kasama K
- Journal Title
  
  Obes Surg.
  
  Volume: Apr;29(4): Issue: 4 Pages: 1195-1201
- DOI
  10.1007/s11695-018-03641-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09339
[Journal Article] Constitutive androstane receptor and pregnane X receptor cooperatively ameliorate DSS-induced colitis.2019
- Author(s)
  Uehara D, Tojima H, Kakizaki S, Yamazaki Y, Horiguchi N, Takizawa D, Sato K, Yamada M, Uraoka T.
- Journal Title
  
  Dig Liver Dis.
  
  Volume: Feb;51(2) Issue: 2 Pages: 226-235
- DOI
  10.1016/j.dld.2018.10.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09339, KAKENHI-PROJECT-17K08387
[Journal Article] A feasibility study of high-dose hypofractionated carbon ion radiation therapy using four fractions for localized hepatocellular carcinoma measuring 3cm or larger.2019
- Author(s)
  Shibuya K, Ohno T, Katoh H, Okamoto M, Shiba S, Koyama Y, Kakizaki S, Shirabe K, Nakano T.
- Journal Title
  
  Radiother Oncol.
  
  Volume: 132 Pages: 230-235
- DOI
  10.1016/j.radonc.2018.10.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08387
[Journal Article] Non-invasive prediction of non-alcoholic steatohepatitis in Japanese patients with morbid obesity by artificial intelligence using rule extraction technology.2018
- Author(s)
  Uehara D, Hayashi Y, Seki Y, Kakizaki S, Horiguchi N, Tojima H, Yamazaki Y, Sato K, Yasuda K, Yamada M, Uraoka T, Kasama K.
- Journal Title
  
  World J Hepatol.
  
  Volume: Dec 27;10(12) Issue: 12 Pages: 934-943
- DOI
  10.4254/wjh.v10.i12.934
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09339, KAKENHI-PROJECT-18K11481, KAKENHI-PROJECT-16K01850
[Journal Article] Indirect activation of pregnane X receptor in the induction of hepatic CYP3A11 by high-dose rifampicin in mice.2017
- Author(s)
  Yamasaki Y, Kobayashi K, Inaba A, Uehara D, Tojima H, Kakizaki S, Chiba K.
- Journal Title
  
  Xenobiotica.
  
  Volume: 11 Issue: 11 Pages: 1-8
- DOI
  10.1080/00498254.2017.1400128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08387
[Journal Article] Faecal lactoferrin is a useful biomarker for mucosal healing in patients with ulcerative colitis during granulocyte and monocyte adsorptive apheresis therapy.2016
- Author(s)
  Sagawa T Kakizaki S, Tomizawa T, et al.
- Journal Title
  
  Colorectal Dis.
  
  Volume: 18 Issue: 7 Pages: 696-702
- DOI
  10.1111/codi.13258
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460941
[Journal Article] Prevalence of nonalcoholic steatohepatitis in Japanese patients with morbid obesity undergoing bariatric surgery.2016
- Author(s)
  Seki Y, Kakizaki S, Horiguchi N, Hashizume H, Tojima H, Yamazaki Y, Sato K, Kusano M, Yamada M, Kasama K.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 51 Issue: 3 Pages: 281-289
- DOI
  10.1007/s00535-015-1114-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460976
[Journal Article] A prospective randomized controlled trial of AJG522 versus standard PEG+E as bowel preparation for colonoscopy.2015
- Author(s)
  Sagawa T, Sato K, Tomizawa T, Mizuide M, Yasuoka H, Shimoyama Y, Kuribayashi S, Kakizaki S, Kawamura O, Kusano M, Yamada M.
- Journal Title
  
  Biomed Res Int.
  
  Volume: 2015 Pages: 521746-521746
- DOI
  10.1155/2015/521756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460941
[Journal Article] Protection against high-fat diet-induced obesity in Helz2-deficient male mice due to enhanced expression of hepatic leptin receptor2014
- Author(s)
  Yoshino S, Satoh T, Yamada M, Hashimoto K, Tomaru T, Katano-Toki A, Kakizaki S, Okada S, Shimizu H, Ozawa A, Tuchiya T, Ikota H, Nakazato Y, Mori M, Matozaki T, Sasaki T, Kitamura T, Mori M.
- Journal Title
  
  Endocrinology.
  
  Volume: 155 Issue: 9 Pages: 3459-3472
- DOI
  10.1210/en.2013-2160
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25112709, KAKENHI-PROJECT-25460941, KAKENHI-PROJECT-26291022, KAKENHI-PROJECT-26461353, KAKENHI-PROJECT-26461374, KAKENHI-PROJECT-26670142
[Journal Article] MK-0626, a selective DPP-4 inhibitor, attenuates hepatic steatosis in ob/ob mice.2014
- Author(s)
  Ohyama T, Sato K, Yamazaki Y, Hashizume H, Horiguchi N, Kakizaki S, Mori M, Kusano M, Yamada M.
- Journal Title
  
  World J Gastroenterol
  
  Volume: 20 Issue: 43 Pages: 16227-35
- DOI
  10.3748/wjg.v20.i43.16227
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460941, KAKENHI-PROJECT-25460976
[Journal Article] Expression of amino acid transporters (LAT1, ASCT2 and xCT) as clinical significance in hepatocellular carcinoma.2014
- Author(s)
  Namikawa M, Kakizaki S, Kaira K, Tojima H, Yamazaki Y, Horiguchi N, Sato K, Oriuchi N, Tominaga H, Sunose Y, Nagamori S, Kanai Y, Oyama T, Takeyoshi I, Yamada M.
- Journal Title
  
  Hepatol Res.
  
  Volume: in press Issue: 9 Pages: 1014-1022
- DOI
  10.1111/hepr.12431
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-24591198, KAKENHI-PUBLICLY-25136714, KAKENHI-PROJECT-25460941, KAKENHI-PROJECT-25461801, KAKENHI-PROJECT-26461895
[Journal Article] Safety and efficacy of balloon-occluded transcatheter arterial chemoembolization using miriplatin for hepatocellular carcinoma.2014
- Author(s)
  Arai H, Abe T, Takayama H, Toyoda M, Ueno T, Kakizaki S, Sato K.
- Journal Title
  
  Hepatol Res.
  
  Volume: 44 Issue: 6 Pages: 663-666
- DOI
  10.1111/hepr.12403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460941
[Journal Article] Transforming growth factor-α activates pancreatic stellate cells and may be involved in matrix metalloproteinase-1 upregulation.2013
- Author(s)
  Tahara H, Sato K, Yamazaki Y, Ohyama T, Horiguchi N, Hashizume H, Kakizaki S, Takagi H, Ozaki I, Arai H, Hirato J, Jesenofsky R, Masamune A, Mori M.
- Journal Title
  
  Lab Invest
  
  Volume: 93 Pages: 720-732
- DOI
  10.1155/2013/458543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460941
[Journal Article] DDCにより誘導される肝障害，肝前駆細胞，オーバル細胞増殖を介した肝再生，修復における核内受容体CARの役割2013
- Author(s)
  山崎勇一、柿崎暁、森昌朋、根岸正彦
- Journal Title
  
  消化器内科
  
  Volume: ５６巻第３号 Pages: 301310-301310
- Data Source
  KAKENHI-PROJECT-24590954
[Journal Article] Carbon dioxide insufflation reduces the discomfort due to colonoscopy as objectively analyzed by salivary stress markers.2013
- Author(s)
  Iida T, Okamura S, Kakizaki S, Sagawa T, Zhang Y, Kobayashi R, Masuo T, Mori M.
- Journal Title
  
  Acta Gastroenterol Belg.
  
  Volume: 76 Pages: 219-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460941
[Journal Article] Azelnidipine is a calcium blocker that attenuates liver fibrosis and may increase antioxidant defence2012
- Author(s)
  Ohyama T, Sato K, Kishimoto K, Yamazaki Y, Horiguchi N, Ichikawa T, Kakizaki S, et al.
- Journal Title
  
  Br J Pharmacol
  
  Volume: 165 Issue: 4b Pages: 1173-87
- DOI
  10.1111/j.1476-5381.2011.01599.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Nuclear receptor CAR-regulated expression of the FAM84A gei during the development of mouse liver tumors.2011
- Author(s)
  Kamino H, Yamazaki Y, Saito K, Takizawa D, Kakizaki S, et al.
- Journal Title
  
  Int J Oncol.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Transforming growth factor-a attenuates hepatic fibrosis : possible involvement of matrix metalloproteinase-12011
- Author(s)
  Ohyama T, Yamazaki Y, Sato K, Horiguchi N, Ichikawa T, Kakizaki S, et al.
- Journal Title
  
  Liver Int
  
  Volume: 31 Issue: 4 Pages: 572-84
- DOI
  10.1111/j.1478-3231.2011.02475.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Nuclear receptor CAR-regulated expression of the FAM84A gene during the development of mouse liver tumors.2011
- Author(s)
  Kamino H, Yamazaki Y, Saito K, Takizawa D, Kakizaki S, et al.
- Journal Title
  
  Int J Oncol. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Constitutive active/androstane receptor promotes hepatocarcinogenesis in amouse model of non-alcoholic steatohepatitis2011
- Author(s)
  Takizawa D, Kakizaki S, et al.
- Journal Title
  
  Carcinogenesis
  
  Volume: 32 Issue: 4 Pages: 576-83
- DOI
  10.1093/carcin/bgq277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Hepatocyte growth factor overexpression ameliorates liver inflammation and fibrosis in a mouse model of nonalcoholic steatohepatitis.2011
- Author(s)
  Tojima H, Kakizaki S, et al.
- Journal Title
  
  Hepatol Int. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Nuclear receptor CAR-regulated expression of the FAM84A gene during the development of mouse liver tumors2011
- Author(s)
  Kamino H, Yamazaki Y, Saito K, Takizawa D, Kakizaki S, et al
- Journal Title
  
  Int J Oncol
  
  Volume: 38 Pages: 20-1511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Constitutive active/androstane receptor promotes hepatocarcinogenesis in a mouse model of non-alcoholic steatohepatitis.2011
- Author(s)
  Takizawa D, Kakizaki S, et al.
- Journal Title
  
  Carcinogenesis
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Hepatocyte growth factor overexpression ameliorates liver inflammation and fibrosis in a mouse model of nonalcoholic steatohepatitis2011
- Author(s)
  Tojima H, Kakizaki S, et al.
- Journal Title
  
  Hepatol Int
  
  Volume: (印刷中) Issue: 3 Pages: 620-630
- DOI
  10.1007/s12072-011-9301-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759, KAKENHI-PROJECT-22790631
[Journal Article] Nuclear receptor CAR-regulated expression of the FAM84A gene during the development of mouse liver tumors2011
- Author(s)
  Kamino H, Yamazaki Y, Saito K, Takizawa D, Kakizaki S, et al.
- Journal Title
  
  Int J Oncol
  
  Volume: 38 Pages: 1511-20
- DOI
  10.3892/ijo.2011.980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Constitutive active/androstane receptor promotes hepato-carcinogenesis in a mouse model of non-alcoholic steatohepatitis2011
- Author(s)
  Takizawa D, Kakizaki S, et al
- Journal Title
  
  Carcinogenesis
  
  Volume: 32 Pages: 83-576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Constitutive active/androstane receptor promotes hepatocarcinogenesis in a mouse model of non-alcoholic steatohepatitis.2011
- Author(s)
  Takizawa D, Kakizaki S, et al.
- Journal Title
  
  Carcinogenesis. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Hepatocyte growth factor overexpression ameliorates liver inflam mation and fibrosis in a mouse model of nonalcoholic steatohepa titis.2011
- Author(s)
  Tojima H, Kakizaki S, et al.
- Journal Title
  
  Hepatol Int.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Nuclear Receptors CAR and PXR ; therapeutic targets for cholestatic liver disease2011
- Author(s)
  Kakizaki S, et al
- Journal Title
  
  Front Biosci
  
  Volume: 17 Pages: 2988-3003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Nuclear receptors CAR and PXR ; therapeutic targets for cholestatic liver disease2011
- Author(s)
  Kakizaki S, et al.
- Journal Title
  
  Front Biosci
  
  Volume: 17 Issue: 1 Pages: 2988-3005
- DOI
  10.2741/3893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Histone deacetylase inhibitors induce cytochrome P450 2B by activating nuclear receptor constitutive androstane receptor.2010
- Author(s)
  Takizawa D, Kakizaki S, et al.
- Journal Title
  
  Drug Metab Dispos. 38
  
  Pages: 1493-1498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Histone deacetylase inhibitors induce cytochrome P450 2B by activating nuclear receptor constitutive androstane receptor.2010
- Author(s)
  Takizawa D, Kakizaki S, et al.
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 38 Pages: 1493-1498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Fucosylated fraction of alpha-fetoprotein as a predictor of prognosis in patients with hepatocellular carcinoma after curative treatment2010
- Author(s)
  Tamura Y, Igarashi M, Suda T, Wakai T, Umemura T, Tanaka E, Kakizaki S, et al
- Journal Title
  
  Dig Dis Sci.
  
  Volume: 55 Pages: 101-2095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Histone deacetylase inhibitors induce cytochrome P450 2B by activating nuclear receptor constitutive and rostane receptor2010
- Author(s)
  Takizawa D, Kakizaki S, et al
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 38 Pages: 8-1493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Xenobiotic-Sensing Nuclear Receptors CAR and PXR as Drug Targets in Cholestatic Liver Disease.2009
- Author(s)
  Kakizaki S, et al.
- Journal Title
  
  Curr Drug Targets. 10
  
  Pages: 1184-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Xenobiotic-sensing nuclear receptors CAR and PXR as drug targets in cholestatic liver disease.2009
- Author(s)
  Kakizaki S, et al.
- Journal Title
  
  Curr Drug Targets. 10
  
  Pages: 1156-1163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] プレドニゾロンのジェネリック医薬品への変更により増悪した自己免疫性肝炎の1例2009
- Author(s)
  柿崎暁, 他
- Journal Title
  
  日本消化器病学会雑誌 VOL.106
  
  Pages: 1488-1493
- NAID
  10026133910
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592272
[Journal Article] 異所性静脈瘤の経験と治療戦略2009
- Author(s)
  柿崎暁, 他
- Journal Title
  
  日本門脈圧亢進症学会雑誌 VOL.15
  
  Pages: 143-148
- NAID
  130001922321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592272
[Journal Article] Xenobiotic-sensing nuclear receptors CAR and PXR as drug targets in cholestatic liver disease2009
- Author(s)
  Kakizaki S, et al
- Journal Title
  
  Curr Drug Targets
  
  Volume: 10 Pages: 1156-1163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Hepatocyte growth factor protects against Fas-mediated liver apoptosis in transgenic mice2009
- Author(s)
  Suzuki H, Toyoda M, Horiguchi N, Kakizaki S, et al
- Journal Title
  
  Liver Int
  
  Volume: 29 Pages: 8-1562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Hepatocyte growth factor protects against Fas-mediated liver apoptosis in transgenic mice.2009
- Author(s)
  Suzuki H, Toyoda M, Horiguchi N, Kakizaki S, et al.
- Journal Title
  
  Liver Int. 29
  
  Pages: 1562-1568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Interstrain differences in susceptibility to non-alcoholic steatohepatitis2008
- Author(s)
  Yamazaki Y, Kakizaki S, et al
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 23 Pages: 82-276
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] New insights on the xenobiotic-sensing nuclear receptors in liver diseases-CAR and PXR-2008
- Author(s)
  Kakizaki S, et al
- Journal Title
  
  Curr Drug Metab
  
  Volume: 9 Pages: 21-614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Non alcoholic fatty liver disease in Japanese patients with severe obesity who received laparoscopic Roux-en-Y gastric bypasssurgery (LRYGB) in comparison to non-Japanese patients.2008
- Author(s)
  Kakizaki S, et. al.
- Journal Title
  
  J Gastroenterol. 43
  
  Pages: 86-92
- NAID
  10021267427
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter.2008
- Author(s)
  Sugatani J, Mizushima K, Osabe M, Yamakawa K, Kakizaki S, et. al.
- Journal Title
  
  Naunyn Schmiedebergs Arch Pharmacol.
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Interstrain differences in susceptibility to non-alcoholic steatohepatitis2008
- Author(s)
  Yamazaki Y, Kakizaki S, Takizawa D, Ichikawa T, Sato K, Takagi H, Mori M.
- Journal Title
  
  J Gastroenterol Hepatol 23
  
  Pages: 276-82
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Non alcoholic fatty liver disease in Japanese patients with severe obesity who received laparoscopic Roux-en-Y gastric bypass surgery (LRYGB) in comparison to non-Japanese patients2008
- Author(s)
  Kakizaki S, Takizawa D, Yamazaki Y, Nakajima Y, Ichikawa T, Sato K, Takagi H, Mori M, Kasama K.
- Journal Title
  
  J Gastroenterol 43
  
  Pages: 86-92
- NAID
  10021267427
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Interstrain differences in susceptibility to non-alcoholic steatohenatitis.2008
- Author(s)
  Yamazaki Y, Kakizaki S, et al.
- Journal Title
  
  J Gastroenterol Hepatol. 23
  
  Pages: 276-282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] New insights on the xenobiotic-sensing nuclear receptors in liver diseases--CAR and PXR--.2008
- Author(s)
  Kakizaki S, et al.
- Journal Title
  
  Curr Drug Metab. 9
  
  Pages: 614-621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Elevated plasma resistin concentrations in patients with liver cirrhosis.2008
- Author(s)
  Kakizaki S, et. al.
- Journal Title
  
  J Gastroenterol Hepatol. 23
  
  Pages: 73-77
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Interstrain differences in susceptibility to non-alcoholic steatohepatitis2008
- Author(s)
  Yamazaki Y, Kakizaki S, et. al.
- Journal Title
  
  J Gastroenterol Hepatol 23
  
  Pages: 276-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Nonalcoholic fatty liver disease in Japanese patients with severe obesity who received laparoscopic Roux-en-Y gastric bypass surgery(LRYGB)in comparison to non-Japanese patients.2008
- Author(s)
  Kakizaki S, et al.
- Journal Title
  
  J Gastroenterol. 43
  
  Pages: 86-92
- NAID
  10021267427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Overexpression of NK2 promotes liver fibrosis in carbon tetrachloride-induced chronic liver injury2008
- Author(s)
  Hagiwara S, Otsuka T, Yamazaki Y, Kosone T, Sohara N, Ichikawa T, Sar￥to K, Kakizaki S, et al
- Journal Title
  
  Liver Int
  
  Volume: 28 Pages: 31-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs : implication of defects in the UGT1A1 gene promoter2008
- Author(s)
  Sugatani J, Mizushima K, Osabe M, Yamakawa K, Kakizaki S, et al
- Journal Title
  
  Naunyn Schmiedebergs Arch Pharmacol.
  
  Volume: 377 Pages: 597-605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Non alcoholic fatty liver disease in Japanese patients with severe obesity who received laparoscopic Roux-en-Y gastric bypass surgery (LRYGB) in comparison to non-Japanese patients2008
- Author(s)
  Kakizaki S, et al
- Journal Title
  
  J Gastroenterol.
  
  Volume: 43 Pages: 86-92
- NAID
  10021267427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Non alcoholic fatty liver disease in Japanese patients with severe obesity who received laparoscopic Roux-en-Y gastric bypass surgery(LRYGB)n comparison to non-Japanese patients2008
- Author(s)
  Kakizaki S, et. al.
- Journal Title
  
  J Gastroenterol 43
  
  Pages: 86-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Nonalcoholic fatty liver disease in Japanese patients with severe obesity who received laparoscopic Roux-en-Y gastric bypass surgery (LRYGRB) in comparison to non-Japanese patients.2008
- Author(s)
  Kakizaki S, et al.
- Journal Title
  
  J Gastroenterol. 43
  
  Pages: 86-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Transforming growth factor-alpha accelerates hepatocyte repopulation after hepatocyte transplantation2008
- Author(s)
  Kosone T, Takagi H, Horiguchi N, Kakizaki S, et al
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 23 Pages: 6-260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Interstrain differences in susceptibility to non-alcoholic steatohepatitis.2008
- Author(s)
  Yamazaki Y, Kakizaki S, et. al.
- Journal Title
  
  J Gastroenterol Hepatol. 23
  
  Pages: 276-82
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter2008
- Author(s)
  Sugatani J, Mizushima K, Osabe M, Yamakawa K, Kakizaki S, Takagi H, Mori M, Ikari A, Miwa M.
- Journal Title
  
  Naunyn Schmiedebergs Arch Pharmacol (Epub ahead of print)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Elevated plasma resistin concentrations in patients with liver cirrhosis2008
- Author(s)
  Kakizaki S, et. al.
- Journal Title
  
  J Gastroenterol Hepatol 23
  
  Pages: 73-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] New insights on the xenobiotic-sensing nuclear receptors in liver diseases-CAR and PXR-.2008
- Author(s)
  Kakizaki S, et al.
- Journal Title
  
  Curr Drug Metab. 9
  
  Pages: 614-621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590759
[Journal Article] Transcriptional regulation of human UGTIAl gene expression through distal and proximal promoter motifs:implication of defects in the UGT1Al gene promoter2008
- Author(s)
  Sugatani J, Mizushima K, Osabe M, Yamakawa K, Kakizaki S, et. al.
- Journal Title
  
  Naunyn Schmiedebergs Arch Pharmacol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] The role of nuclear receptor CAR in the pathogenesis of non-alcoholic steatohepatitis2007
- Author(s)
  Yamazaki Y, Kakizaki S, et. al.
- Journal Title
  
  Gut 56
  
  Pages: 565-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] HGF ameliorates a high-fat diet-induced fatty liver.2007
- Author(s)
  Kosone T, Takagi H, Horiguchi N, Ariyama Y, Otsuka T, Sohara N, Kakizaki S, et. al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol. 293
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Hepatobiliary and pancreatic: Multifocal nodular hepatic steatosis associated with the metabolic syndrome2007
- Author(s)
  Ichikawa T, Oh-I S, Kaira K, Kakizaki S, Sato K, Takagi H, Mori M.
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 1693-1693
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] HGF ameliorates a high-fat diet-induced fatty liver2007
- Author(s)
  Kosone T, Takagi H, Horiguchi N, Ariyama Y, Otsuka T, Sohara N, Kakizaki S, et. al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Primary liver cancers with nonalcoholic steatohepatitis2007
- Author(s)
  Hashizume H, Sato K, Takagi H, Hirokawa T, Kojima A, Sohara N, Kakizaki S, Mochida Y, Shimura T, Sunose Y, Ohwada S, Mori M.
- Journal Title
  
  Eur J Gastroenterol Hepatol 19
  
  Pages: 827-34
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] The role of nuclear receptor CAR in the pathogenesis of non-alcoholic steatohepatitis2007
- Author(s)
  Yamazaki Y, Kakizaki S, et al.
- Journal Title
  
  Gut. (In press)
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Hepatocellular carcinoma in young adults-The clinical characteristics,prognosis and the findings of a patient survival analysis.2007
- Author(s)
  YAmazaki Y, Kakizaki S. et al.
- Journal Title
  
  Dig Dis Sci. (In press)
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Primary liver cancers with nonalcoholic steatohepatitis2007
- Author(s)
  Hashizume H, Sato K, Takagi H, Hirokawa T, Kojima A, Sohara N, Kakizaki S, et. al.
- Journal Title
  
  Eur J Gastroenterol Hepatol 19
  
  Pages: 827-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Hepatobiliary and pancreatic: Multifocal nodular hepatic steatosis associated with the metabolic syndrome.2007
- Author(s)
  Ichikawa T, Oh-I S, Kaira K, Kakizaki S, et. al.
- Journal Title
  
  J Gastroenterol Hepatol. 22
  
  Pages: 1693-93
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Hepatobiliary and pancreatic:Multifocal nodular hepatic steatosis associated with the metabolic syndrome2007
- Author(s)
  Ichikawa T, Oh-I S, Kaira K, Kakizaki S, et. al.
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 1693-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Hepatocyte growth factor accelerates thrombopoiesis in transgenic mice.2007
- Author(s)
  Kosone T, Takagi H, Horiguchi N, Toyoda M, Kakizaki S, et al.
- Journal Title
  
  Lab Invest. (In press)
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Elevated plasma resistin concentrations in patients with liver cirrhosis.2007
- Author(s)
  Kakizaki S, et al.
- Journal Title
  
  J Gastroenterol Hepatol. (In press)
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Primary liver cancers with nonalcoholic steatohepatitis.2007
- Author(s)
  Hashizume H, Sato K, Takagi H, Hirokawa T, Kojima A, Sohara N, Kakizaki S, et. al.
- Journal Title
  
  Eur J Gastroenterol Hepatol. 19
  
  Pages: 827-34
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] The role of nuclear receptor CAR in the pathogenesis of non-alcoholic steatohepatitis2007
- Author(s)
  Yamazaki Y, Kakizaki S, Horiguchi N, Sohara N, Sato K, Takagi H, Mori M, Negishi M.
- Journal Title
  
  Gut 56
  
  Pages: 565-74
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Gene expression profiles of drug-metabolizing enzymes and transporters with an overexpression of hepatocyte growth factor.2007
- Author(s)
  Kakizaki S, et. al.
- Journal Title
  
  Liver Int. 27
  
  Pages: 109-19
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] The role of nuclear receptor CAR in the pathogenesis of non-alcoholic steatohepatitis.2007
- Author(s)
  Yamazaki Y, Kakizaki S, et. al.
- Journal Title
  
  Gut 56
  
  Pages: 565-74
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Gene expression profiles of drug-metabolizing enzymes and transporters with an overexpression of hepatocyte growth factor2007
- Author(s)
  Kakizaki S, Yamazaki Y, Kosone T, Horiguchi N, Sohara N, Sato K, Takagi H, Yoshinari K, Mori M.
- Journal Title
  
  Liver Int 27
  
  Pages: 109-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Gene expression profiles of drug-metabolizing enzymes and transporters with an overexpression of hepatocyte growth factor2007
- Author(s)
  Kakizaki S, et. al.
- Journal Title
  
  Liver Int 27
  
  Pages: 109-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] HGF ameliorates a high-fat diet-induced fatty liver2007
- Author(s)
  Kosone T, Takagi H, Horiguchi N, Ariyama Y, Otsuka T, Sohara N, Kakizaki S, Sato K, Mori M.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 293
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Gene expression profiles of drug-metabolizing enzymes and transporters with an overexpression of hepatocyte growth factor.2007
- Author(s)
  Kakizaki S, et al.
- Journal Title
  
  Liver International. 27
  
  Pages: 109-119
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Adult onset type II citrullinemia as a cause of non-alcoholic steatohepatitis.2006
- Author(s)
  Takagi H, Hagiwara S, Hashizu me H, Kanda D, Sato K, Sohara N, Kakizaki S, et. al.
- Journal Title
  
  J Hepatol. 44
  
  Pages: 236-9
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Adult onset type II citrullinemia as a cause of non-alcoholic steatohepatitis2006
- Author(s)
  Takagi H, Hagiwara S, Hashizume H, Kanda D, Sato K, Sohara N, Kakizaki S, Takahashi H, Mori M, Kaneko H, Ohwada S, Ushikai M, Kobayashi K, Saheki T.
- Journal Title
  
  J Hepatol 44
  
  Pages: 236-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Adult onset type II citrullinemia as a cause of non-alcoholic steatohepatitis.2006
- Author(s)
  Takagi H, Hagiwara S, Hashizumi H, kanda D, Sato K, Sohara N, Kakizaki S, et al.
- Journal Title
  
  J Hepatol. 44
  
  Pages: 236-9
- Data Source
  KAKENHI-PROJECT-18590716
[Journal Article] Role of nuclear receptor CAR in carbon tetrachloride-induced hepatotoxicity.2005
- Author(s)
  Yamazaki Y, Kakizaki S, et al.
- Journal Title
  
  World J Gastroenterol. 11(38)
  
  Pages: 5966-5972
- Data Source
  KAKENHI-PROJECT-15790337
[Journal Article] Novel CAR-mediated mechanism for synergistic activation of two distinct elements within the human cytochrome P450 2B6 gene in HepG2 cells.2005
- Author(s)
  Swales K, Kakizaki S, et al.
- Journal Title
  
  J Biol Chem. 280(5)
  
  Pages: 3458-3466
- Data Source
  KAKENHI-PROJECT-15790337
[Presentation] 化学物質によるPXR活性化のマウス肝発がんへの影響解析2020
- Author(s)
  志津怜太、石村麻衣、信澤純人、保坂卓臣、佐々木崇光、柿崎暁、吉成浩一
- Organizer
  第47回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20K07202
[Presentation] Induction of hepatocyte-specific gene expression by a novel nuclear receptor2017
- Author(s)
  S. Sasaki, M. Urabe, T. Maeda, J. Suzuki, R. Irie, S. Kakizaki, F.J. Gonzalez, and Y. Inoue
- Organizer
  4th International Symposium of Gunma University Medical Innovation and Advanced Micro-Device Engineering
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08728
[Presentation] Induction of hepatocyte-specific gene expression by a novel nuclear receptor.2017
- Author(s)
  Sasaki S, Urabe M, Maeda T, Suzuki J, Irie R, Kakizaki S, Gonzalez FJ, Inoue Y.
- Organizer
  4th International Symposium of Gunma University Medical Innovation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08387
[Presentation] 核内レセプターからみた肝疾患「核内レセプターCAR(constitutive androstane receptor)の肝疾患における役割」2016
- Author(s)
  柿崎暁,山崎勇一,Masahiko Negishi.
- Organizer
  第52回日本肝臓学会総会　（ワークショップ）
- Place of Presentation
  千葉市（日本）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-25460941
[Presentation] Development of new therapeutic agents for inflammatory bowel diseases targeting the nuclear receptor CAR/PXR.2016
- Author(s)
  Kakizaki S, Uehara D, Yamazaki Y, Horiguchi N, Inoue Y.
- Organizer
  GUMI&AMDE 2016(第3回群馬大学医療開発国際シンポジウム, 第８回先端マイクロデバイス工学国際会議）
- Place of Presentation
  桐生市（日本）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460941
[Presentation] Positive regulation of Hepatic miRNA by HNF4α2016
- Author(s)
  Akiyama M, Morimoto A, Kannari M, Tsuchida Y, Matsuta T, Saito C, Sasaki S, Kakizaki S, Gonzalez FJ, Inoue Y.
- Organizer
  3rd International Symposium of GUMI&AMDE2016
- Place of Presentation
  桐生市民会館
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08728
[Presentation] 肝細胞癌株におけるIGFBP-1を介した核内受容体PXR活性化による形態変化、細胞遊走2015
- Author(s)
  山崎勇一、児玉進、柿崎暁、他
- Organizer
  第57回日本消化器病学会大会
- Place of Presentation
  グランドプリンスホテル新高輪（東京）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25460941
[Presentation] Fecal lactoferrin is a useful biomarker for mucosal healing in cases of ulcerative colitis during monocyte adsorptive apheresis therapy.2015
- Author(s)
  Tomizawa T Kakizaki S, Sagawa T, et al.
- Organizer
  APDW2015(アジア太平洋消化器病学会）
- Place of Presentation
  台北市（台湾）
- Year and Date
  2015-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460941
[Presentation] IGFBP1 mediates pregnane X receptor-induced morphological changes and migration of hepatocellular carcinoma cells.2015
- Author(s)
  Yamazaki Y, Kodama S, Kakizaki S, et al.
- Organizer
  APDW2015(アジア太平洋消化器病学会）
- Place of Presentation
  台北市（台湾）
- Year and Date
  2015-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460941
[Presentation] Malignant peripheral Nerve tumor of liver.2015
- Author(s)
  Horiguchi N, Kakizaki S,Takizawa D, Yamazaki Y, Sato K, Ohno Y, Kusano M, Yamada M.
- Organizer
  第２５回アジア大西洋消化器病学会
- Place of Presentation
  Taipei Taiwan
- Year and Date
  2015-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460976
[Presentation] Nuclear receptor CAR (NR1I3) is essential for DDC-induced liver injury and oval cell proliferation in mouse liver2011
- Author(s)
  Yamazaki Y, Kakizaki S, et al
- Organizer
  The Liver Meeting 2011(アメリカ肝臓学会)
- Place of Presentation
  アメリカ合衆国・サンフランシスコ・モスコーンウエスト国際会議場
- Year and Date
  2011-11-06
- Data Source
  KAKENHI-PROJECT-20590759
[Presentation] Constitutive active/androstane receptor promotes hepatocarcinogenesis in a mouse model of non-alcoholic steatohepatitis2011
- Author(s)
  Takizawa D, Kakizaki S, et al
- Organizer
  DDW2011(アメリカ消化器病週間)
- Place of Presentation
  アメリカ合衆国・シカゴ・マコーミックプレース国際会議場
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-20590759
[Presentation] Constitutive active/androstane receptor promotes hepatocarcinogenesis in amouse model of non-alcoholic steatohepatitis2011
- Author(s)
  Takizawa D, Kakizaki S, et al.
- Organizer
  DDW 2011(アメリカ消化器病週間)
- Place of Presentation
  アメリカ合衆国・シカゴ・マコーミックプレース国際会議場
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-20590759
[Presentation] Transforming growth factor-α attenuates hepatic fibrosis : possible involvement of matrix metalloproteinase-12011
- Author(s)
  Ohyama T, Yamazaki Y, Sato K, Horiguchi N, Ichikawa T, Kakizaki S, et al.
- Organizer
  DDW 2011(アメリカ消化器病週間)
- Place of Presentation
  アメリカ合衆国・シカゴ・マコーミックプレース国際会議場
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-20590759
[Presentation] Nuclear receptor CAR (NR113) is essential for DDC-induced liver injury and oval cell proliferation in mouse liver2011
- Author(s)
  Yamazaki Y, Kakizaki S, et al.
- Organizer
  The Liver Meeting 2011(アメリカ肝臓学会)
- Place of Presentation
  アメリカ合衆国・サンフランシスコ・モスコーンウエスト国際会議場
- Year and Date
  2011-11-06
- Data Source
  KAKENHI-PROJECT-20590759
[Presentation] Transforming growth factor-α attenuates hepatic fibrosis : possible involvement of matrix metalloproteinase-12011
- Author(s)
  Ohyama T, Yamazaki Y, Sato K, Horiguchi N, Ichikawa T, Kakizaki S, et al
- Organizer
  DDW2011(アメリカ消化器病週間)
- Place of Presentation
  アメリカ合衆国・シカゴ・マコーミックプレース国際会議場
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-20590759
[Presentation] Nuclear xenobiotic receptor CAR is essential for DDC to proliferate oval cells in mouse liver.2010
- Author(s)
  Yamazaki Y, Moore R, Kakizaki S, et al.
- Organizer
  18^<th> International Symposium on Microsomes and Drug Oxidations.
- Place of Presentation
  Beijing, China
- Year and Date
  2010-05-17
- Data Source
  KAKENHI-PROJECT-20590759
[Presentation] HGF promotes DEN-induced hepatocarcinogenesis, but attenuates MCD-induced liver inflammation and fibrosis.2010
- Author(s)
  Horiguchi N, Kakizaki S, et al.
- Organizer
  AASLD Liver meeting.
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2010-11-01
- Data Source
  KAKENHI-PROJECT-20590759
[Presentation] Nuclear xenobiotic receptor CAR is essential for DDC to proliferate oval cells in mouse liver.2010
- Author(s)
  Yamazaki Y, Moore R, Kakizaki S, et al.
- Organizer
  18^<th> International Symposium on Microsomes Drug Oxidations
- Place of Presentation
  Beijing, China
- Year and Date
  2010-05-17
- Data Source
  KAKENHI-PROJECT-20590759
[Presentation] Hepatocyte growth factor overexpression ameliorates liver inflammation and fibrosis in a mouse model of nonalcoholic steatohepatitis.2010
- Author(s)
  Kakizaki S, et al.
- Organizer
  18^<th> UEGW.
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2010-10-27
- Data Source
  KAKENHI-PROJECT-20590759
[Presentation] Nuclear xenobiotic receptor CAR is essential for DDC to proliferate oval cells in mouse liver2010
- Author(s)
  Yamazaki Y, Moore R, Kakizaki S, et al
- Organizer
  18^<th> International Symposium on Microsomes and Drug Oxidations
- Place of Presentation
  中国・北京
- Year and Date
  2010-05-17
- Data Source
  KAKENHI-PROJECT-20590759
[Presentation] Nonalcoholic fatty liver disease in Japanese patients with severe obesity who received laparoscopic Roux-en-Y gastric bypass surgery(LRYGB)in comparison to non-Japanese patients.2008
- Author(s)
  Kakizaki S, et al.
- Organizer
  109^<th> annual meeting of the AGA institute.
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-20590759
[Presentation] Non alcoholic fatty liver disease in Japanese patients with severe obesity who received laparoscopic Roux-en-Y gastric bypass surgery (LRYGB)2007
- Author(s)
  Kakizaki S, Takagi H, Kasama K.
- Organizer
  The 49th annual meeting of Japanese Society of Gastroenterology
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Presentation] 非アルコール性脂肪性肝炎の病態における核内受容体CARの役割2007
- Author(s)
  山崎勇一、柿崎暁、他
- Organizer
  第49回日本消化器病学会大会
- Place of Presentation
  神戸
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Presentation] The role of nuclear receptor CAR in the pathogenesis of non-alcoholic steatohepatitis2007
- Author(s)
  Yamazaki Y, Kakizaki S, Takizawa D, Horiguchi N, Sohara N, Sato K, Takagi H, Mori M.
- Organizer
  The 49th annual meeting of Japanese Society of Gastroenterology
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Presentation] 高度肥満に対する腹腔鏡下胃バイパス術前後での肝機能の検討2007
- Author(s)
  柿崎暁、他
- Organizer
  第49回日本消化器病学会大会
- Place of Presentation
  神戸
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Presentation] Clinicopathological analyses of nine cases of primary liver cancers with nonalcoholic steatohepatitis2006
- Author(s)
  Hashizume H, Toyoda M, Katakai K, Arai T, Sato K, Kojima A, Hirokawa T, Sohara N, Kakizaki S, Takagi H, Mori M, Mochida Y, Shimura T, Sunose Y, Kawate S, Ohwada S.
- Organizer
  The 42nd annual meeting of Japanese Society of Hepatology
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Presentation] Hepatic malignancies in patients with nonalcoholic steatohepatitis.2006
- Author(s)
  Sato K, Hashizume H, Kojima A, Sohara N, Kakizaki S, at al.
- Organizer
  2006年度アメリカ消化器病週間
- Place of Presentation
  アメリ力合衆国ロサンゼルス
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Presentation] The role of nuclear receptor CAR in the pathogenesis of non-alcoholic steatohepatitis.2006
- Author(s)
  Yamazaki Y, Kakizaki S, et. al.
- Organizer
  第14回ヨーロッパ消化器病週間
- Place of Presentation
  ドイツベルリン
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Presentation] Adult onset type II citrullinemia is complicated with non-alcoholic steatohepatitis.2006
- Author(s)
  Takagi H, Kobayashi K, Ichikawa T, Sato K, Sohara N, Kakizaki S, et al.
- Organizer
  第14回ヨーロッパ消化器病週間
- Place of Presentation
  ドイツベルリン
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Presentation] The role of nuclear receptor CAR in the pathogenesis of non-alcoholic steatohepatitis2006
- Author(s)
  Yamazaki Y, Kakizaki S, Horiguchi N, Sohara N, Sato K, Takagi H, Mori M, Negishi M.
- Organizer
  14th UEGW (United European Gastroenterology Week)
- Place of Presentation
  Berlin, Germany
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Presentation] Adult onset type II citrullinemia is complicated with non-alcoholic steatohepatitis2006
- Author(s)
  Takagi H, Kobayashi K, Ichikawa T, Sato K, Sohara N, Kakizaki S, Mori M.
- Organizer
  14th UEGW (United European Gastroenterology Week)
- Place of Presentation
  Berlin, Germany
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Presentation] Hepatic malignancies in patients with nonalcoholic steatohepatitis2006
- Author(s)
  Sato K, Hashizume H, Kojima A, Sohara N, Kakizaki S, Takagi H, Mori M.
- Organizer
  Digestive Disease Week 2006
- Place of Presentation
  Los Angeles, USA.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590716
[Presentation] Nonalcoholic steatohepatitis (NASH) に合併した原発性肝癌9症例の臨床病理学的検討2006
- Author(s)
  橋爪洋明豊田満夫片貝堅志荒井泰道佐藤賢小島明廣川朋之蘇原直人柿崎暁、他
- Organizer
  第42回日本肝臓学会総会
- Place of Presentation
  京都
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590716

1. YOSHINARI Koichi (60343399)

# of Collaborated Projects: 7 results

# of Collaborated Products: 3 results
2. Yamazaki Yuichi (00582404)

# of Collaborated Projects: 7 results

# of Collaborated Products: 7 results
3. HORIGUCHI NORIO (10550022)

# of Collaborated Projects: 5 results

# of Collaborated Products: 8 results
4. Inoue Yusuke (90304302)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
5. 戸島洋貴 (80807537)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. 山田英二郎 (60645563)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. 阪口政清 (70379840)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 志津怜太 (50803912)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. TAHARA Hiroki

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. 市川武 (60420105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 保坂卓臣 (30611579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 井上貴子 (00431700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 植原大介 (70850139)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 柴田康博 (90344936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKIZAWA Daichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAGAMORI Shushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 的崎尚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 金井好克

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kakizaki Satoru 柿崎 暁

KAKIZAKI Satoru 柿崎 暁

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前立腺癌の去勢抵抗性獲得メカニズムとリン酸化核内受容体の病態解明Principal Investigator

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The role of nuclear receptor CAR in the pathogenesis of intrahepatic cholangiocellular carcinomaPrincipal Investigator

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The role of nuclear receptors PXR/CAR in the pathogenesis of inflammatory bowel diseases.Principal Investigator

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Kakizaki Satoru 柿崎暁

KAKIZAKI Satoru 柿崎暁