SASAGAWA Satoru 笹川覚

… Alternative Names

笹川覚ササガワサトル

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Researcher Number	80345115
Other IDs	https://orcid.org/0000-0001-5769-8700
Affiliation (Current)	2024: 医療法人徳洲会野崎徳洲会病院(附属研究所), 研究所, 部長
Affiliation (based on the past Project Information) *help	2024: 医療法人徳洲会野崎徳洲会病院(附属研究所), 研究所, 部長 2022: 医療法人徳洲会野崎徳洲会病院(附属研究所), 研究所, 部長 2021: 医療法人徳洲会野崎徳洲会病院(附属研究所), 研究所, 主任研究員 2016 – 2020: 医療法人徳洲会野崎徳洲会病院(附属研究所), 研究所, 部長 2014 – 2015: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), その他部局等, その他 … More 2012 – 2014: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), その他部局等, 研究員 2009: 京都府立医科大学, 医学系研, 助教 2005: 東京大学, 大学院・情報理工学系研究科, 科学技術振興特任研究員 2004: University of Tokyo, Graduate School of Information Science and Technology, Project Researcher, 大学院情報理工学系研究科, 科学技術振興特任研究員 2003 – 2004: 東京大学, 大学院・情報理工学系研究科, 科学技術振興特任研究員(常勤形態) Less
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery / General medical chemistry Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 滑膜肉腫 / Twist1 / 転移 / 骨軟部腫瘍 / フェロトーシス / 薬剤耐性 / スフェロイド / オルガノイド / ABCB7 / 転位 … More / HDACの阻害剤 / 免疫療法 / NK細胞 / がん微小環境 / 免疫回避 / HDAC阻害剤 / 免疫監視 / MICA/B / 転移の分子メカニズム / 自然免疫応答 / 転移能 / 骨肉腫 / 幹細胞性 / 転移メカニズム … More Except Principal Investigator 生体生命情報 / シグナル伝達 / システム生物学 / bioinformatics / systems biology / signal transduction / バイオインフォマティクス / バイオインフォマティク / 安定性 / 血管収縮 / シグナル伝逹 / NMDA受容体 / システム生物 / シナプス可塑性 Less

Analysing cellular characterization of synovial sarcoma and therapeutic model with ferroptosis inductionPrincipal Investigator
- Principal Investigator
  
  笹川覚
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  医療法人徳洲会野崎徳洲会病院(附属研究所)
骨軟部腫瘍の肺転移における治療抵抗性メカニズムの解析Principal Investigator
- Principal Investigator
  
  笹川覚
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  医療法人徳洲会野崎徳洲会病院(附属研究所)
Investigating the new strategy to suppress lung metastasis of sarcomasPrincipal Investigator
- Principal Investigator
  
  Sasagawa Satoru
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  医療法人徳洲会野崎徳洲会病院(附属研究所)
Understanding molecular mechanism underlying innate immune system escape for metastasis in sarcomaPrincipal Investigator
- Principal Investigator
  
  Sasagawa Satoru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  医療法人徳洲会野崎徳洲会病院(附属研究所)
  Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
Investigation of collective molecular mechanisms in stemness and metastasis in sarcomaPrincipal Investigator
- Principal Investigator
  
  SASAGAWA Satoru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
造血幹細胞・白血病関連因子のシステム解析による新規な生物作用の解明Principal Investigator
- Principal Investigator
  
  笹川覚
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto Prefectural University of Medicine
System analysis of stability and plasticity of signal transduction
- Principal Investigator
  
  KURODA Shinya
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Systems analysis of molecular networks based on biochemical computational simulations
- Principal Investigator
  
  KURODA Shinya
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tokyo

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2005 Other

All Journal Article Presentation

[Journal Article] Lung fibrosis is a novel therapeutic target to suppress lung metastasis of osteosarcoma2022
- Author(s)
  Yui Yoshihiro、Kumai Jun、Watanabe Kenta、Wakamatsu Toru、Sasagawa Satoru
- Journal Title
  
  International Journal of Cancer
  
  Volume: - Issue: 5 Pages: 739-751
- DOI
  10.1002/ijc.34008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09051, KAKENHI-PROJECT-19K18482, KAKENHI-PROJECT-21K09290, KAKENHI-PROJECT-21K09338
[Journal Article] Establishment of organoids from human epithelioid sarcoma with the air-liquid interface organoid cultures.2022
- Author(s)
  Wakamatsu T, Ogawa H, Yoshida K, Matsuoka Y, Shizuma K, Imura Y, Tamiya H, Nakai S, Yagi T, Nagata S, Yui Y, Sasagawa S, Takenaka S
- Journal Title
  
  Front. Oncol.
  
  Volume: 12 Pages: 893592-893592
- DOI
  10.3389/fonc.2022.893592
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09290, KAKENHI-PROJECT-21K09338, KAKENHI-PROJECT-22K16766, KAKENHI-PROJECT-19K18481, KAKENHI-PROJECT-20K18048
[Journal Article] The CDK4/6-UCHL5-BRD4 axis confers resistance to BET inhibitors in MLL-rearranged leukemia cells by suppressing BRD4 protein degradation2022
- Author(s)
  Amari Keigo、Sasagawa Satoru、Imayoshi Natsuki、Toda Yuki、Hosogi Shigekuni、Imamura Toshihiko、Ashihara Eishi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 588 Pages: 147-153
- DOI
  10.1016/j.bbrc.2021.12.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09051, KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20J22374, KAKENHI-PROJECT-20K17388
[Journal Article] Establishment of organoids from human epithelioid sarcoma with the air-liquid interface organoid cultures2022
- Author(s)
  Toru Wakamatsu, Hisataka Ogawa, Keiichi Yoshida, Yukiko Matsuoka, Kazuko Shizuma, Yoshinori Imura, Hironari Tamiya, Sho Nakai, Toshinari Yagi, Shigenori Nagata, Yoshihiro Yui, Satoru Sasagawa and Satoshi Takenaka
- Journal Title
  
  Frontiers in Oncology
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09338
[Journal Article] A Novel Method for Polyacrylamide Gel Preparation Using N-hydroxysuccinimide-acrylamide Ester to Study Cell-Extracellular Matrix Mechanical Interactions2021
- Author(s)
  Kumai Jun、Sasagawa Satoru、Horie Masanobu、Yui Yoshihiro
- Journal Title
  
  Frontiers in Materials
  
  Volume: 8 Pages: 637278-637278
- DOI
  10.3389/fmats.2021.637278
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09051, KAKENHI-PROJECT-19K18482, KAKENHI-PROJECT-18K14063
[Journal Article] Molecular evidence of IGFBP-3 dependent and independent VD3 action and its nonlinear response on IGFBP-3 induction in prostate cancer cells2020
- Author(s)
  Igarashi Ko、Yui Yoshihiro、Watanabe Kenta、Kumai Jun、Nishizawa Yasuko、Miyaura Chisato、Inada Masaki、Sasagawa Satoru
- Journal Title
  
  BMC Cancer
  
  Volume: 20 Issue: 1 Pages: 802-802
- DOI
  10.1186/s12885-020-07310-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09051, KAKENHI-PROJECT-19K18482, KAKENHI-PROJECT-19KK0194, KAKENHI-PROJECT-18H02571, KAKENHI-PROJECT-18K16641, KAKENHI-PROJECT-20H02534
[Journal Article] Low-dose eribulin reduces lung metastasis of osteosarcoma in vitro and in vivo.2019
- Author(s)
  Watanabe K, Yui Y, Sasagawa S, Suzuki K, Kanamori M, Yasuda T, Kimura T.
- Journal Title
  
  Oncotarget
  
  Volume: 10(2) Issue: 2 Pages: 161-174
- DOI
  10.18632/oncotarget.26536
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09051, KAKENHI-PROJECT-18K16641, KAKENHI-PROJECT-17K10961, KAKENHI-PROJECT-17K16681
[Journal Article] Evidence for intrathecal sodium butyrate as a novel option for leptomeningeal metastasis.2018
- Author(s)
  Nakagawa H, Yui Y, Sasagawa S, Itoh K.
- Journal Title
  
  Journal of Neuro-Oncology
  
  Volume: 印刷中 Issue: 1 Pages: 43-50
- DOI
  10.1007/s11060-018-2852-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10458, KAKENHI-PROJECT-15K15560, KAKENHI-PROJECT-18K09051, KAKENHI-PROJECT-18K16641
[Journal Article] Sodium butyrate induces senescence and inhibits the invasiveness of glioblastoma cells.2018
- Author(s)
  Nakagawa H, Sasagawa S, Itoh K.
- Journal Title
  
  Oncology letter
  
  Volume: 15(2) Pages: 1495-1502
- DOI
  10.3892/ol.2017.7518
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10458, KAKENHI-PROJECT-15K15560, KAKENHI-PROJECT-18K09051
[Journal Article] Trabectedin is a promising antitumour agent for synovial sarcoma2016
- Author(s)
  Yasui, H., Imura, Y., Outani, H., Hamada, K., Nakai, T., Yamada, S., Takenaka, S., Sasagawa, S., Araki, N., Itoh, K., Myoui, A., Yoshikawa, H., & Naka, N.
- Journal Title
  
  Journal of Chemotherapy
  
  Volume: e-pub ahead of print Issue: 5 Pages: 1-8
- DOI
  10.1080/1120009x.2015.1133013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15560, KAKENHI-PROJECT-16H05448, KAKENHI-PROJECT-15K10458
[Journal Article] Trabectedin is a promising antitumour agent for synovial sarcoma2016
- Author(s)
  Takaaki Nakai, Shutaro Yamada, Satoshi Takenaka, Satoru Sasagawa, Nobuhito Araki, Kazuyuki Itoh, Akira Myoui, Hideki Yoshikawa, Norifumi Naka
- Journal Title
  
  Journal of Chemotherapy
  
  Volume: e-pub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10458
[Journal Article] Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription.2015
- Author(s)
  Takeda S, Sasagawa S, Oyama T, Searleman AC, Westergard TD, Cheng EH, Hsieh JJ.
- Journal Title
  
  The Journal of Clinical Investigation
  
  Volume: 125(3) Issue: 3 Pages: 1203-1214
- DOI
  10.1172/jci77075
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24791575, KAKENHI-PROJECT-15K10458
[Journal Article] Deflection of VEGF action by SS18-SSX and composite VEGF- and CXCR4-targeted therapy in synovial sarcoma.2014
- Author(s)
  Wakamatsu T, Naka N, Sasagawa S, Tanaka T, Takenaka S, Araki N, Ueda T, Nishizawa Y, Yoshikawa H, Itoh K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 105 Issue: 9 Pages: 1124-1134
- DOI
  10.1111/cas.12469
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592233, KAKENHI-PROJECT-24791575, KAKENHI-PROJECT-25670661
[Journal Article] Tailored therapeutic strategies for synovial sarcoma : Receptor tyrosine kinase pathway analyses predict sensitivity to the mTOR inhibitor RAD0012014
- Author(s)
  Yasui, H., Naka, N., Imura, Y., Outani, H., Kaneko, K., Hamada, KI., Sasagawa, S., Araki, N., Ueda, T., Itoh, K., Myoui, A., and Yoshikawa, H
- Journal Title
  
  Cancer Lett
  
  Volume: 347(1) Issue: 1 Pages: 114-122
- DOI
  10.1016/j.canlet.2014.01.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390372, KAKENHI-PROJECT-24592233, KAKENHI-PROJECT-24791575, KAKENHI-PROJECT-25670661
[Journal Article] HGF-MET signals via the MLL-ETS2 complex in hepatocellular carcinoma.2013
- Author(s)
  Takeda S, Liu H, Sasagawa S, Dong Y, Trainor PA, Cheng EH, Hsieh JJ.
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 347(1) Issue: 7 Pages: 3154-3165
- DOI
  10.1172/jci65566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791575
[Journal Article] Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs.2013
- Author(s)
  Oyama T, Sasagawa S, Takeda S, Hess RA, Lieberman PM, Cheng EH, Hsieh JJ.
- Journal Title
  
  Developmental Cell
  
  Volume: 27(2) Issue: 2 Pages: 188-120
- DOI
  10.1016/j.devcel.2013.09.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791575
[Journal Article] Involvement of SIK3 in Glucose and Lipid Homeostasis in Mice2012
- Author(s)
  Uebi T, Itoh Y, Hatano O, Kumagai A, Sanosaka M, Sasaki T, Sasagawa S, Doi J, Tatsumi K, Mitamura K, Morii E, Aozasa K, Kawamura T, Okumura M, Nakae J, et al.
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 5 Pages: e37803-e37803
- DOI
  10.1371/journal.pone.0037803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590995, KAKENHI-PROJECT-22591101, KAKENHI-PROJECT-23390040, KAKENHI-PROJECT-23590209, KAKENHI-PROJECT-23791048, KAKENHI-PROJECT-24390222, KAKENHI-PROJECT-24390354, KAKENHI-PROJECT-24790333, KAKENHI-PROJECT-24791575
[Journal Article] Prediction and validation of the distinct dynamics of transient and sustained ERK activation2005
- Author(s)
  Sasagawa, S. et al.
- Journal Title
  
  Nature Cell Biology 7, (4)
  
  Pages: 365-373
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15014206
[Journal Article] Prediction and validation of the distinct dynamics of transient And sustained ERK activation2005
- Author(s)
  Sasagawa, S. et al.
- Journal Title
  
  Nature Cell Biology 7・4
  
  Pages: 365-373
- Data Source
  KAKENHI-PROJECT-15014206
[Journal Article] Prediction and validation of the distinct dynamics of transient and sustained ERK activation2005
- Author(s)
  Sasagawa, S. et al.
- Journal Title
  
  Nature Cell Biology 7
  
  Pages: 365-373
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15014206
[Journal Article] Dynamic characteristics of transient responses2005
- Author(s)
  Ozaki, Y., Sasagawa, S., Kuroda, S.
- Journal Title
  
  J.Biochem. 137
  
  Pages: 659-663
- NAID
  10017345350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17017005
[Journal Article] Prediction and validation of the distinct dynamics of transient and sustained ERK activation2005
- Author(s)
  Sasagawa, S., Ozaki, Y. Fujita, K., Kuroda, S.
- Journal Title
  
  Nat.Cell Biol. 7
  
  Pages: 365-373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17017005
[Presentation] 滑膜肉腫細胞に対するHDAC阻害剤とSN38の併用効果2022
- Author(s)
  笹川覚
- Organizer
  第26回　日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09338
[Presentation] 滑膜肉腫における転移環境条件とTwist1によるMICA/Bの発現抑制とHDAC阻害剤による MICA/Bの発現回復2021
- Author(s)
  笹川覚、熊井準、由井理洋
- Organizer
  日本癌学会　第80回学術総会
- Data Source
  KAKENHI-PROJECT-18K09051
[Presentation] 滑膜肉腫におけるMICA/Bの発現調節とそれを利用した免疫療法による転移抑制の検討2019
- Author(s)
  笹川覚
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K09051
[Presentation] Vitamin D can enhance the effects of Anti-tumor treatment in prostate tumor cells.2019
- Author(s)
  Satoru Sasagawa
- Organizer
  ASCB|EMBO 2019 meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09051
[Presentation] 滑膜肉腫におけるNKG2Dリガンドの発現調節と転移制御2018
- Author(s)
  笹川覚、由井理洋、渡邉健太、伊藤和幸、水本篤志、中川秀光
- Organizer
  日本癌学会第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K09051
[Presentation] Analysis of metastatic potential regulated by Twist1 in synovial sarcoma2017
- Author(s)
  Satoru Sasagawa, Yoshihiro Yui, Kenta Watanabe, Hidemitsu Nakagawa, Kazuyuki Itoh.
- Organizer
  日本癌学会　第76回学術総会
- Data Source
  KAKENHI-PROJECT-15K10458
[Presentation] Regulation of Metastatic Potential by Twist1 in Sarcoma2016
- Author(s)
  S. Sasagawa, Y. Yui, H. Nakagawa, K. Itoh
- Organizer
  日本癌学会
- Place of Presentation
  横浜（パシフィコ横浜）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K10458
[Presentation] INVESTIGATING THE FUNCTIONAL ROLE AND EXPRESSION CONTROL OF TWIST1 IN SARCOMA2013
- Author(s)
  Satoru Sasagawa, Kazuyuki Itoh
- Organizer
  The Connective Tissue Society
- Place of Presentation
  New York, Sheraton Hotel
- Data Source
  KAKENHI-PROJECT-24791575
[Presentation] 骨軟部腫瘍におけるTwist1の発現と機能解析2013
- Author(s)
  笹川覚、伊藤和幸
- Organizer
  日本がん転移学会
- Place of Presentation
  松本市　ホテルブエナビスタ
- Data Source
  KAKENHI-PROJECT-24791575
[Presentation] Sarcomaの転移におけるTwist1の発現制御と機能的役割の解析2013
- Author(s)
  笹川覚、伊藤和幸
- Organizer
  日本癌学会
- Place of Presentation
  横浜市　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24791575
[Presentation] Salt-Inducible Kinase 3 is critical for chondrocyte hypertrophy during bone development2012
- Author(s)
  Satoru Sasagawa, Kazuyuki Itoh
- Organizer
  The Americal Society for Cell Biology
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-24791575
[Presentation] 骨軟部腫瘍の転移driverの同定と転移抑制のための分子標的探索
- Author(s)
  笹川覚、伊藤和幸
- Organizer
  第47回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  大阪国際会議場（大阪市）
- Year and Date
  2014-07-17 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-24791575
[Presentation] 骨軟部腫瘍の転移ドライバの同定と発現制御および分子標的としての可能性の検討
- Author(s)
  笹川覚、伊藤和幸
- Organizer
  第７３回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24791575

1. OZAKI Yuichi (70345114)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. KURODA Shinya (50273850)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. KAWATO Mitsuo (10144445)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. MAEDA Akio (30361538)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. ITOH Kazuyuki (20301806)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
6. SIVAKUMARAN Sudhir (70361540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YOSHIKAWA Hideki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. NAKA Norifumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. ARAKI Nobuhito

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HAMADA Kenichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. JOYAMA Shin

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. WAKAMATSU Toru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TANAKA Takaaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 中江淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 由井理洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SASAGAWA Satoru 笹川 覚

笹川 覚 ササガワ サトル

Research Projects

Research Products

Co-Researchers

Analysing cellular characterization of synovial sarcoma and therapeutic model with ferroptosis inductionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

骨軟部腫瘍の肺転移における治療抵抗性メカニズムの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigating the new strategy to suppress lung metastasis of sarcomasPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Understanding molecular mechanism underlying innate immune system escape for metastasis in sarcomaPrincipal Investigator

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Investigation of collective molecular mechanisms in stemness and metastasis in sarcomaPrincipal Investigator

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造血幹細胞・白血病関連因子のシステム解析による新規な生物作用の解明Principal Investigator

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System analysis of stability and plasticity of signal transduction

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Systems analysis of molecular networks based on biochemical computational simulations

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[Journal Article] Lung fibrosis is a novel therapeutic target to suppress lung metastasis of osteosarcoma2022

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[Journal Article] Establishment of organoids from human epithelioid sarcoma with the air-liquid interface organoid cultures.2022

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[Journal Article] The CDK4/6-UCHL5-BRD4 axis confers resistance to BET inhibitors in MLL-rearranged leukemia cells by suppressing BRD4 protein degradation2022

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[Journal Article] Establishment of organoids from human epithelioid sarcoma with the air-liquid interface organoid cultures2022

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[Journal Article] A Novel Method for Polyacrylamide Gel Preparation Using N-hydroxysuccinimide-acrylamide Ester to Study Cell-Extracellular Matrix Mechanical Interactions2021

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[Journal Article] Molecular evidence of IGFBP-3 dependent and independent VD3 action and its nonlinear response on IGFBP-3 induction in prostate cancer cells2020

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SASAGAWA Satoru 笹川覚

笹川覚ササガワサトル