HASHIRAMOTO AKIRA 柱本照

… Alternative Names

柱本照ハシラモトアキラ

Hashiramoto Akira 柱本照

HASHIRAMOTO Akira 柱本照

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Researcher Number	80346246
Other IDs
External Links
Affiliation (Current)	2025: 神戸大学, 保健学研究科, 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 神戸大学, 保健学研究科, 教授 2018 – 2020: 神戸大学, 保健学研究科, 教授 2008 – 2010: Kobe University, 医学研究科, 特命准教授 2007: Kobe University, 医学部, 准教授 2007: Kobe University, FES School of Medicine, Associate Professor 2003 – 2006: 神戸大学, 医学部, 客員助教授 2004: Kobe University, School of Medicine, Associate Professor, 医学部, 助教授
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学 / Basic Section 54020:Connective tissue disease and allergy-related Except Principal Investigator Basic Section 52010:General internal medicine-related / Orthopaedic surgery / Biological Sciences
Keywords	Principal Investigator 関節リウマチ / 時計遺伝子 / TNF-a / Dbl / 概日リズム / 時間生物学 / RNAシーケンス / PARA-ｂZIP / TEF / Bmal1 … More / 滑膜細胞 / Ｂｍａｌ１ / rheumatoid arthritis / Cry gene / circadian rhythum / 関節炎 / Cry / TNF-α / Cry遺伝子 / Rheumatoid arthritis / 遺伝子除去マウス / ポリソムノグラフ / アクチグラフ / Beck Depression Inventory / Epworth sleepiness scale / ピッツバーグ睡眠質問表 / 睡眠障害 / 睡眠 … More Except Principal Investigator DR3 / disease gene / 関節リウマチ / 血漿/脳脊髄液 / 認知症 / バイオマーカー / 炎症 / マイクロRNA / アルツハイマー病 / Apoptosis / Rheumatoid Arthritis / TL1A / アポトーシス / death receptor 3 (DR3) / rheumatoid arthritis (RA) / 慢性関節リウマチ / 遺伝解析 / Dbl / Ang-1 / 関節破壊 / DR3,death receptor 3 / genetic predisposition / 遺伝素因 / 疾患遺伝子 / rheumatoid arthritis / 内科 / テクノバイオロジー / 免疫学 / 遺伝子 / 遺伝学 / 関節リウマチ rheumatoid arthritis(RA) / death receptor 3(DR3) / アポトーシス apoptosis Less

認知症における新規血中バイオマーカーの探索～炎症誘導性マイクロRNAの意義～
- Principal Investigator
  
  吉田幸祐
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kobe University
Tef 遺伝子改変マウスを用いた関節リウマチ病態解析と創薬へのアプローチPrincipal Investigator
- Principal Investigator
  
  柱本照
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kobe University
Development of chronotherapy for rheumatoid arthritis targeting the clock gene Bmal1.Principal Investigator
- Principal Investigator
  
  Hashiramoto Akira
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kobe University
Sleep disturbance and related changes of circadian rhythm in patients with rheumatoid arthritis.Principal Investigator
- Principal Investigator
  
  HASHIRAMOTO Akira
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kobe University
Disruption of circadian rhythm aggravates experimental arthritis: study in cry gene-knockout mice.Principal Investigator
- Principal Investigator
  
  HASHIRAMOTO Akira
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kobe University
Research of pathogenesis of rheumatoid arthritis by TL1A knock out mice
- Principal Investigator
  
  MIURA Yasushi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kobe University
Research of rheumatoid arthritis using Dbl knock-out micePrincipal Investigator
- Principal Investigator
  
  HASHIRAMOTO Akira
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kobe University
Studies on the causative disease gene in autoimmunity and rheumatoid arthritis
- Principal Investigator
  
  SHIOZAWA Shunichi
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University

[Journal Article] Initiation of belimumab with higher daily prednisolone is effective for rapid glucocorticoid reduction: A 96-week retrospective study2024
- Author(s)
  Yamane Takashi、Hashiramoto Akira
- Journal Title
  
  Lupus
  
  Volume: 0 Issue: 6 Pages: 0-0
- DOI
  10.1177/09612033241240859
- Data Source
  KAKENHI-PROJECT-22K08563
[Journal Article] The clock gene Bmal1 controls inflammatory mediators in rheumatoid arthritis fibroblast-like synoviocytes2024
- Author(s)
  Kenta Kaneshiro, Kanako Nakagawa, Hikari Tsukamoto, Genta Matsuoka, Seitaro Okuno, Koji Tateishi, Yasuhiro Terashima, Nao Shibanuma, Kohsuke Yoshida, Akira Hashiramoto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 8 Pages: 149315-149323
- DOI
  10.1016/j.bbrc.2023.149315
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15347, KAKENHI-PROJECT-22K08563
[Journal Article] A case of chronic eosinophilic pneumonia associated with rheumatoid arthritis in Glucocorticoid-free remission with JAK inhibitor: A case report.2023
- Author(s)
  Yamane T, Hashiramoto A.
- Journal Title
  
  Medicine (Baltimore).
  
  Volume: - Pages: 102-105
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08563
[Journal Article] A case of chronic eosinophilic pneumonia associated with rheumatoid arthritis in glucocorticoid-free remission with JAK inhibitor: A case report2023
- Author(s)
  Yamane Takashi、Hashiramoto Akira
- Journal Title
  
  Medicine
  
  Volume: 102 Issue: 13 Pages: e33396-e33396
- DOI
  10.1097/md.0000000000033396
- Data Source
  KAKENHI-PROJECT-22K08563
[Journal Article] Tocilizumab suppresses NF-kappa B activation via toll-like receptor 9 signaling by reducing cell-free DNA in rheumatoid arthritis2023
- Author(s)
  Hashimoto Teppei、Yoshida Kohsuke、Yokoyama Yuichi、Hashimoto Naonori、Kaneshiro Kenta、Yoshikawa Takahiro、Tateishi Koji、Terashima Yasuhiro、Matsui Kiyoshi、Hashiramoto Akira
- Journal Title
  
  Clinical and Experimental Immunology
  
  Volume: 213 Issue: 2 Pages: 209-220
- DOI
  10.1093/cei/uxad064
- Data Source
  KAKENHI-PROJECT-22K08563
[Journal Article] Increased Circulating Cell-Free DNA in Eosinophilic Granulomatosis With Polyangiitis: Implications for Eosinophil Extracellular Traps and Immunothrombosis2022
- Author(s)
  Hashimoto Teppei、Ueki Shigeharu、Kamide Yosuke、Miyabe Yui、Fukuchi Mineyo、Yokoyama Yuichi、Furukawa Tetsuya、Azuma Naoto、Oka Nobuyuki、Takeuchi Hiroki、Kanno Kyoko、Ishida-Yamamoto Akemi、Taniguchi Masami、Hashiramoto Akira、Matsui Kiyoshi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 801897-801897
- DOI
  10.3389/fimmu.2021.801897
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08794, KAKENHI-PROJECT-22K08563
[Journal Article] Chronotherapy targeting cytokine secretion attenuates collagen-induced arthritis in mice2020
- Author(s)
  Yaekura Arisa、Yoshida Kohsuke、Morii Kanta、Oketani Yuto、Okumura Ikumi、Kaneshiro Kenta、Shibanuma Nao、Sakai Yoshitada、Hashiramoto Akira
- Journal Title
  
  International Immunopharmacology
  
  Volume: 84 Pages: 106549-106549
- DOI
  10.1016/j.intimp.2020.106549
- NAID
  120006873062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08408
[Journal Article] Conditional Upregulation of IFN-α Alone Is Sufficient to Induce Systemic Lupus Erythematosus.2019
- Author(s)
  Akiyama C, Tsumiyama K, Uchimura C, Honda E, Miyazaki Y, Sakurai K, Miura Y, Hashiramoto A, Felsher DW, Shiozawa S.
- Journal Title
  
  J Immunol.
  
  Volume: 203 Issue: 4 Pages: 835-843
- DOI
  10.4049/jimmunol.1801617
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08408
[Journal Article] Interleukin-6 and tumour necrosis factor-α cooperatively promote cell cycle regulators and proliferate rheumatoid arthritis fibroblast-like synovial cells.2019
- Author(s)
  Kaneshiro K, Sakai Y, Suzuki K, Uchida K, Tateishi K, Terashima Y, Kawasaki Y, Shibanuma N, Yoshida K, Hashiramoto A.
- Journal Title
  
  Scand J Rheumatol.
  
  Volume: 48 Issue: 5 Pages: 353-361
- DOI
  10.1080/03009742.2019.1602164
- NAID
  120006778281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08408
[Journal Article] Expressions of circadian clock genes represent disease activities of RA patients treated with biological DMARDs.2019
- Author(s)
  Kaneshiro K, Yoshida K, Morii K, Oketani Y, Uchida K, Yaekura A, Okumura I, Hashimoto T, Kawasaki Y, Shibanuma N, Sakai Y, Hashiramoto A.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: 印刷中 Issue: 2 Pages: 293-300
- DOI
  10.1080/14397595.2019.1602242
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16207, KAKENHI-PROJECT-18K08408
[Journal Article] A variant of death-receptor 3 associated with rheumatoid arthritis interferes with apoptosis-induction of T cell.2018
- Author(s)
  Hashiramoto A, Konishi Y, Murayama K, Kawasaki H, Yoshida K, Tsumiyama K, Tanaka K, Mizuhara M, Shiotsuki T, Kitamura H, Komai K, Kimura T, Yagita H, Shiozawa K, Shiozawa S.
- Journal Title
  
  J Biol Chem
  
  Volume: 293 Issue: 6 Pages: 1933-43
- DOI
  10.1074/jbc.m117.798884
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08408, KAKENHI-PROJECT-18K09099
[Journal Article] TNF-α induces expression of the circadian clock gene Bmal1 via dual calcium-dependent pathways in rheumatoid synovial cells.2018
- Author(s)
  Yoshida K, Nakai A, Kaneshiro K, Hashimoto N, Suzuki K, Uchida K, Hashimoto T, Kawasaki Y, Tateishi K, Nakagawa N, Shibanuma N, Sakai Y, Hashiramoto A
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 495 Issue: 2 Pages: 1675-1680
- DOI
  10.1016/j.bbrc.2017.12.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16207, KAKENHI-PROJECT-18K08408
[Journal Article] Methotrexate upregulates circadian transcriptional factors PAR bZIP to induce apoptosis on rheumatoid arthritis synovial fibroblasts.2018
- Author(s)
  Suzuki K, Yoshida K, Ueha T, Kaneshiro K, Nakai A, Hashimoto N, Uchida K, Hashimoto T, Kawasaki Y, Shibanuma N, Nakagawa N, Sakai Y, Hashiramoto A.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 20 Issue: 1 Pages: 55-64
- DOI
  10.1186/s13075-018-1552-9
- NAID
  120006459803
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08408
[Journal Article] Heat shock protein 90 maintains the tumour-like character of rheumatoid synovial cells by stabilizing integrin-linked kinase, extracellular signal-regulated kinase and protein kinase B2011
- Author(s)
  Hashiramoto A, Murata M, Kawazoe T, et al.
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Mammalian clock gene Cryptochrome regulates arthritis via proinflammatory cytokine TNF-alpha2010
- Author(s)
  Hashiramoto A, et al.
- Journal Title
  
  J Immunol 184
  
  Pages: 1560-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Interactions between the genes that regulate the body clock and those that worsen rheumatoid arthritis.2010
- Author(s)
  Shiozawa S, Hashiramoto A.
- Journal Title
  
  Expert Rev Clin Immunol. 6
  
  Pages: 181-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Interactions between the genes that regulate the body clock and those that worsen rheumatoid arthritis.2010
- Author(s)
  Shiozawa S, Hashiramoto A.
- Journal Title
  
  Expert Rev Clin Immunol.
  
  Volume: 6 Pages: 181-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Mammalian clock gene Cryptochrome regulates arthritis via proinflammatory cytokine TNF-alpha.2010
- Author(s)
  Hashiramoto A, Yamane T, Tsumiyama K, Yoshida K, Komai K, Yamada H, Yamazaki F, Doi M, Okamura H, Shiozawa S.
- Journal Title
  
  J Immunol. 184
  
  Pages: 1560-1565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Mammalian clock gene Cryptochrome regulates arthritis via proinflammatory cytokine TNF-alpha.2010
- Author(s)
  Hashiramoto A, Yamane T, Taumiyama K, et al.
- Journal Title
  
  J Immunol.
  
  Volume: 184 Pages: 1560-1565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Prospective study of methotrexate treatment for rheumatoid arthritis treated legitimately according to the government recommended 8 mg/week dose.2009
- Author(s)
  Hashiramoto A, Shiozawa K, Tanaka Y, Yamane T, Murata M, Tanaka C, Terashima Y, Koyama K, Nakagawa N, Abe S, Yoshihara R, Saegusa Y, Tsumiyama K, Komai K, Sakai Y, Shiozawa S.
- Journal Title
  
  Mod Rheumatol.
  
  Pages: 637-642
- NAID
  10027167840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article]2009
- Author(s)
  柱本照(分担執筆)
- Journal Title
  
  リウマチ病セミナー(20)第1章 Myositis とウィルス(永井書店)
  
  Pages: 1-6
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Sjogren's syndrome patients presenting with hypergammaglobulinemia are relatively unresponsive to cevimeline treatment2009
- Author(s)
  Komai K, Shiozawa K, Tanaka Y, Yoshihara R, Tanaka C, Sakai H, Yamane T, Murata M, Tsumiyama K, Hashiramoto A, et al.
- Journal Title
  
  Mod Rheumatol 19
  
  Pages: 416-9
- NAID
  10025113622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Prospective study of methotrexate treatment for rheumatoid arthritis treated legitimately according to the government recommended 8mg/week dose2009
- Author(s)
  Hashiramoto A, et al.
- Journal Title
  
  Mod Rheumatol 19
  
  Pages: 637-42
- NAID
  10027167840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Sjogren's syndrome patients presenting with hypergammaglobulinemia are relatively unresponsive to cevimeline treatment.2009
- Author(s)
  Komai K, Shiozawa K, Tanaka Y, Yoshihara R, Tanaka C, Sakai H, Yamane T,Murata M, Tsumiyama K, Hashiramoto A, Shiozawa S.
- Journal Title
  
  Mod Rheumatol. 19
  
  Pages: 416-419
- NAID
  10025113622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Easy and Accurate Diagnosis of Rheumatoid Arthritis Using Anti-Cyclic Citrullinated Peptide 2 Antibody, Swollen Joint Count, and C-Reactive Protein/Rheumatoid Factor2008
- Author(s)
  Yamane, T, Hashiramoto, A, Tanaka, Y, Tsumiyama, K, Miura, Y, Shiozawa, K, Chihara, K, Shiozawa, S
- Journal Title
  
  J Rheumatol 35(3)
  
  Pages: 414-420
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Journal Article] Treatment of arthritis with a selective inhibitor of c-Fos/activator protein-1.2008
- Author(s)
  Aikawa Y, Morimoto K, Yamamoto T, Chaki H, Hashiramoto A, Narita H, Hirono S, Shiozawa S.
- Journal Title
  
  Nat Biotechnol. 26
  
  Pages: 817-823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Easy and accurate diagnosis of rheumatoid arthritis usinganti-cyclic citrullinated peptide 2 antibody, swollen joint count, and C-reactiveprotein/rheumatoid factor.2008
- Author(s)
  Yamane T, Hashiramoto A, Tanaka Y, Tsumiyama K, Miura Y, Shiozawa K, ChiharaK, Shiozawa S.
- Journal Title
  
  J Rheumatol. 35
  
  Pages: 414-420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Easy and accurate diagnosis of rheumatoid arthritis using anti-cycliceitrullinated peptide 2 antibody, swollen joint count, and C-reactiveprotein/rheumatoid factor.2008
- Author(s)
  Yamane T, Hashiramoto A, Tanaka Y, Tsumiyama K, Miura Y, Shiozawa K, ChiharaK, Shiozawa s.
- Journal Title
  
  J Rheumatol. 35
  
  Pages: 414-420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Low-versus high-baseline epinephrine output shapes opposite innate cytokineprofiles : presence of Lewis-and Fischer-like neurohormonal immune phenotypes in humans?2008
- Author(s)
  Elenkov IJ, Kvetnansky R, Hashiramoto A, Bakalov VK, Link AA, Zachman K, CraneM, Jezova D, Rovensky J, Dimitrov MA, Gold PW, Bonini S, Fleisher T, Chrousos GP, Wilder RL.
- Journal Title
  
  J Immunol. 181
  
  Pages: 1735-1745
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Low- versus high-baseline epinephrine output shapes opposite innate cytokine profiles : presence of Lewis- and Fischer-like neurohormonal immune phenotypes in humans?2008
- Author(s)
  Elenkov IJ, Kvetnansky R, Hashiramoto A, Bakalov VK, Link AA, Zachman K, Crane M, Jezova D, Rovensky J, Dimitrov MA, Gold PW, Bonini S, Fleisher T, Chrousos GP, Wilder RL.
- Journal Title
  
  J Immunol. 181
  
  Pages: 1737-1745
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Treatment of arthritis with a selective inhibitor of c-Fos/activator protein-1.2008
- Author(s)
  Aikawa Y, Morimoto K, Yamamoto T, Chaki H, Hashiramoto A, Narita H, Hirono S, Shiozawa s.
- Journal Title
  
  Nat Biotechnol. 26
  
  Pages: 817-823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591170
[Journal Article] Easy and Accurate Diagnosis of Rheumatoid Arthritis Using Anti-Cyclic Citrullinated Peptide 2 Antibody, Swollen Joint Count, and C-Reactive Protein/Rheumatoid Factor.2008
- Author(s)
  Yamane T, Hashiramoto A, Tanaka Y, Tsumiyama K, Miura Y, Shiozawa K, Chihara K, Shiozawa S.
- Journal Title
  
  J Rheumatol 35
  
  Pages: 414-420
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591110
[Journal Article] Angiopoietin 1 directly induces destruction of the rheumatoid joint by cooperative, but independent, signaling via ERK/MAPK and phosphatidylinositol3-kinase/Akt2007
- Author(s)
  Hashiramoto, A, Sakai, C, Yoshida, K, Tsumiyama, K, Miura, Y, Shiozawa, K, Nose, M, Komai, K, Shiozawa, S
- Journal Title
  
  Arthritis Rheum 56(7)
  
  Pages: 2170-2179
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Journal Article] Decoy receptor 3 expressed in rheumatoid synovial fibroblasts protects the cells against fas-induced apoptosis2007
- Author(s)
  Hayashi, S, Miura, Y, Nishiyama, T, Mitani, M, Tateishi, K, Sakai, Y, Hashiramoto, A, Kurosaka, M, Shiozawa, S, Doita, M
- Journal Title
  
  Arthritis Rheum 56(4)
  
  Pages: 1067-1075
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Journal Article] Decoy receptor 3 expressed in rheumatoid synovial fibroblasts protects the cells against fas-induced apoptosis.2007
- Author(s)
  Hayashi S, Miura Y, Nishiyama T, Mitani M, Tateishi K, Sakai Y, Hashiramoto A, Kurosaka M, Shiozawa S, Doita M
- Journal Title
  
  Arthritis Rheum 56・1
  
  Pages: 1067-1075
- Data Source
  KAKENHI-PROJECT-18591110
[Journal Article] Decoy receptor 3 expressed in rheumatoid synovial fibroblasts protects the cells against fas-induced apoptosis.2007
- Author(s)
  Hayashi S, Miura Y, Nishiyama T, Mitani M, Tateishi K, Sakai Y, Hashiramoto A, Kurosaka M, Shiozawa S, Doita M.
- Journal Title
  
  Arthritis Rheum. 56
  
  Pages: 1067-1075
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591110
[Journal Article] Angiopoietin 1 directly induces destruction of the rheumatoid joint by cooperative, but independent, signaling via ERK/MAPK and phosphatidylinositol 3-kinase/Akt.2007
- Author(s)
  Hashiramoto A, Sakai C, Yoshida K, Tsumiyama K, Miura Y, Shiozawa K, Nose M, Komai K, Shiozawa S.
- Journal Title
  
  Arthritis Rheum. 56
  
  Pages: 2170-2179
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591110
[Journal Article] Ganglioside GM3promotes cell migration by regulating MAPK and c-Fos/AP-12006
- Author(s)
  Hashiramoto, A, Mizukami, H, Yamashita, T
- Journal Title
  
  Oncogene 25(28)
  
  Pages: 3948-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Journal Article] Ganglioside GM3promotes cell migration by regulating MAPK and c-Fos/AP-1.2006
- Author(s)
  Hashiramoto A, Mizukami H, Yamashita T
- Journal Title
  
  Oncogene 25・28
  
  Pages: 3948-3955
- Data Source
  KAKENHI-PROJECT-18591110
[Journal Article] Ganglioside GM3promotes cell migration by regulating MAP K and c-Fos/AP-1.2006
- Author(s)
  Hashiramoto A, Mizukami H, Yamashita T.
- Journal Title
  
  Oncogene 25
  
  Pages: 3948-55
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591110
[Journal Article] Hypermethylated promoter region of DR3, the death receptor 3 gene, in rheumatoid arthritis synovial cells.2006
- Author(s)
  Takami N, Osawa K, Miura Y, Komai K, Taniguchi M, Shiraishi M, Sato K, Iguchi T, Shiozawa K, Hashiramoto A, Shiozawa S
- Journal Title
  
  Arthritis Rheum. 54・3
  
  Pages: 779-787
- Data Source
  KAKENHI-PROJECT-18591110
[Journal Article] Hypermethylated promoter region of DR3, the death receptor 3 gene, in rheumatoid arthritis synovial cells2006
- Author(s)
  Takami, N, Osawa, K, Miura, Y, Komai, K, Taniguchi, M, Shiraishi, M, Sato, K, Iguchi, T, Shiozawa, K, Hashiramoto, A, Shiozawa, S
- Journal Title
  
  Arthritis Rheum 54(3)
  
  Pages: 779-87
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Journal Article] Anchorage on fibronectin via VIA-5(a5b1 integrin)protects rheumatoid synovialcells from Fas-induced apoptosis2006
- Author(s)
  Kitagawa, A, Miura, Y, Saura, R, Mitani, M, Ishikawa, H, Hashiramoto, A, Yoshiya, S, Shiozawa, S, Kurosakam M
- Journal Title
  
  Ann Rheum Dis 65(6)
  
  Pages: 721-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Journal Article] Hypermethylated promoter region of DR3, the death receptor 3 gene, in rheumatoid arthritis synovial cells.2006
- Author(s)
  Takami N, Osawa K, Miura Y, Komai K, Taniguchi M, Shiraishi M, Sato K, Iguchi T, Shiozawa K, Hashiramoto A, Shiozawa S.
- Journal Title
  
  Arthritis Rheum. 54
  
  Pages: 779-87
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591110
[Journal Article] Estrogen specifically stimulates expression and production of osteoprotegerin from rheumatoid synovial fibroblasts.2005
- Author(s)
  Mitani M, Miura Y, Saura R, Kitagawa A, Fukuyama T, Hashiramoto A, Shiozawa S, Kurosaka M, Yoshiya S.
- Journal Title
  
  Int J Mol Med 5
  
  Pages: 827-32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13204059
[Journal Article] Heat shock protein 90 is required for increased DNA binding activity of activator protein-1, a heterodimer of Fos/JunD, in rheumatoid synovial cells under inflammatory stimuli.2005
- Author(s)
  Murata M, Miura Y, Hashiramoto A, Kitamura H, Kawasaki H, Shiozawa K, Yoshiya S, Baba H, Chihara K, Shiozawa S.
- Journal Title
  
  Int J Mol Med 15
  
  Pages: 645-653
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13204059
[Journal Article] Linkage解析によるRA関連遺伝子2005
- Author(s)
  柱本照
- Journal Title
  
  ゲノム医学 5.1
  
  Pages: 33-38
- Data Source
  KAKENHI-PROJECT-15591055
[Journal Article] Death receptor 3 (DR3)gene duplication in a chromosome region 1p36.3 : Gene duplication is more prevalent in rheumatoid arthritis patients.2004
- Author(s)
  Osawa K, Takami N, Shiozawa K, Hashiramoto A, Shiozawa S.
- Journal Title
  
  Gene Immunity 5
  
  Pages: 439-43
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13204059
[Journal Article] 関節リウマチと分子シャペロン-HSP90を介した滑膜細胞のシグナル伝達系-2004
- Author(s)
  柱本照
- Journal Title
  
  臨床リウマチ 16.3
  
  Pages: 181-187
- Data Source
  KAKENHI-PROJECT-15591055
[Journal Article] Human wee 1 kinase is directly transactivated by and increased in association with c-Fos/AP-1 : Rheumatoid synovial cells overexpressing these genes go into aberrant mitosis.2003
- Author(s)
  Kawasaki H, Komai K, Nakamura M, Yamamoto E, OuYang Z, Nakashima T, Hashiramoto A, Shiozawa K, Ishikawa H, Kurosaka M, Shiozawa S.
- Journal Title
  
  Oncogene 22
  
  Pages: 6839-6844
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13204059
[Journal Article] p21 is down-regulated in conjunction with up-regulation of c-Fos in the lymphocytes of rheumatoid arthritis patients.2003
- Author(s)
  Hikasa M, Yamamoto E, Kawasaki H, Komai K, Shiozawa K, Hashiramoto A, Miura Y, Shiozawa S.
- Journal Title
  
  Biochem Biophys Res Commun 304
  
  Pages: 143-147
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13204059
[Journal Article] Anchorage on fibronectin via VLA-5 (α5β1 integrin) protects rheumatoid synovial cells from Fas-induced apoptosis.
- Author(s)
  Kitagawa A, Miura Y, Saura R, Mitani M, Ishikawa H, Hashiramoto A, Yoshiya S, Shiozawa S, Kurosaka M.
- Journal Title
  
  Ann Rheum Dis (in press.)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13204059
[Journal Article] The promoter region of death receptor 3 (DR3) is specifically hypermethylated in rheumatoid synovial cells.
- Author(s)
  Takami N, Osawa K, Miura Y, Komai K, Taniguchi M, Shiraishi M, Sato K, Iguchi T, Shiozawa K, Hashiramoto A, Shiozawa S.
- Journal Title
  
  Arthritis Rheum (in press.)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13204059
[Presentation] APOEε4アリルが脳脊髄液/血漿中の炎症性マイクロRNA発現量に及ぼす影響2023
- Author(s)
  齋藤ののか吉田幸祐大川愛美安東俊三郎中田葉子高野和貴藤田純樫林哲雄古和久朋柱本照高橋竜一
- Organizer
  第42回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06866
[Presentation] アルツハイマー病を鑑別する上での血漿中炎症性マイクロRNA測定の意義2023
- Author(s)
  吉田幸祐齋藤ののか安東俊三郎大川愛美中田葉子高野和貴藤田純樫林哲雄古和久朋柱本照高橋竜一
- Organizer
  第42回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06866
[Presentation] Clock gene Bmal1 promotes transcriptional activity of NF-κB to regulate production of inflammatory mediators in RA-FLS.2023
- Author(s)
  Hikari Tsukamoto, Kenta Kaneshiro, Kohsuke Yoshida, Koji Tateishi, Yasuhiro Terashima, Nao Shibanuma, Yoshitada Sakai, Akira Hashiramoto
- Organizer
  米国リウマチ学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08563
[Presentation] 時計遺伝子Bmal1はRA-FLSの炎症性メディエーター発現を制御する2023
- Author(s)
  金城健太、吉田幸祐、塚本光里、奥野征太郎、松岡元太、川崎善子、立石耕司、寺島康浩、柴沼均、酒井良忠、柱本照
- Organizer
  第67回日本リウマチ学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08563
[Presentation] RA滑膜細胞におけるTNFα誘導性Tef遺伝子発現低下のメカニズム：3’UTR結合miRNAを対象とした研究2023
- Author(s)
  吉田幸祐、、金城健太、塚本光里、立石耕司、寺島康浩、川崎善子、柴沼均、酒井良忠、柱本照
- Organizer
  第67回日本リウマチ学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08563
[Presentation] 時計遺伝子Bmal1はRA-FLSの炎症性メディエーターの産生を制御する2023
- Author(s)
  松岡元太、金城健太、吉田幸祐、立石耕司、寺島康浩、柴沼均、柱本照
- Organizer
  第９回JCRベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-22K08563
[Presentation] IL-6はBcl2ファミリー蛋白を介して関節リウマチ滑膜細胞の細胞死抵抗性を制御する2023
- Author(s)
  橫見優里、塚本光里、金城健太、川崎善子、吉田幸祐、立石耕司、寺島康浩、柴沼均、酒井良忠、柱本照
- Organizer
  第９回JCRベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-22K08563
[Presentation] 時計制御遺伝子Tef は細胞増殖活性とTNFα産生を制御する2023
- Author(s)
  塚本光里、吉田幸祐、金城健太、立石耕司、寺島康浩、柴沼均、酒井良忠、柱本照
- Organizer
  第67回日本リウマチ学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08563
[Presentation] 時計遺伝子Bmal1はRA滑膜細胞の炎症性メディエーター産生を制御する2022
- Author(s)
  中川加奈子、金城健太、吉田幸祐、川崎善子、立石耕司、寺島康浩、柴沼均、酒井良忠、柱本照
- Organizer
  第66回日本リウマチ学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08563
[Presentation] 時計制御遺伝子Tef は細胞周期調節因子およびPI3K-Akt経路を介してRA滑膜細胞の増殖に関与する2022
- Author(s)
  塚本光里、森本奈都子、福住美希、金城健太、吉田幸祐、立石耕司、寺島康浩、柴沼均、酒井良忠、柱本照
- Organizer
  第９回JCRベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-22K08563
[Presentation] 時計制御遺伝子Tef はRA滑膜細胞の増殖に関与する2022
- Author(s)
  森本奈都子、中川加奈子、福住美希、吉田幸祐、川崎善子、立石耕司、寺島康浩、柴沼均、酒井良忠、柱本照
- Organizer
  第66回日本リウマチ学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08563
[Presentation] 関節リウマチにおけるバリシチニブを用いた時間薬物療法～多施設共同前向き比較試験～2022
- Author(s)
  橋本哲平、柱本照、安部武生、吉田幸祐、野口和照、壷井和幸、吉川卓宏、立石耕司、寺島　康浩、山根隆志、柴沼均、松井聖
- Organizer
  第31回日本リウマチ学会　近畿支部学術集会
- Data Source
  KAKENHI-PROJECT-22K08563
[Presentation] IL-6、TNFα刺激によるRA滑膜細胞の増殖は時計制御遺伝子Tefによって制御される2020
- Author(s)
  森井寛太、桶谷優斗、金城健太、奥村郁美、八重倉愛里沙、吉田幸祐、川崎善子、立石耕司、寺島康浩、柴沼均、酒井良忠、柱本照
- Organizer
  第64回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] TNFα誘導性CCL2は転写因子RORα/REV-ERBα、ヒストンアセチル化酵素CBP/p300を介してRA滑膜細胞の遊走に関与する2020
- Author(s)
  奥村郁美、吉田幸祐、金城健太、八重倉愛里沙、桶谷優斗、森井寛太、立石耕司、寺島康浩、川崎善子、柴沼均、酒井良忠、柱本照
- Organizer
  第64回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] JAK阻害剤Baricitinibを用いた薬物時間療法はマウス関節炎を効果的に抑制する2020
- Author(s)
  八重倉愛里沙、森井寛太、桶谷優斗、奥村郁美、金城健太、吉田幸祐、川崎善子、柴沼均、酒井良忠、柱本照
- Organizer
  第64回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] IL-6は時計遺伝子を介して関節リウマチ滑膜細胞に細胞死抵抗性をもたらす2019
- Author(s)
  桶谷優斗、内田京、鈴木行人、金城健太、森井寛太、八重倉愛里沙、奥村郁美、吉田幸祐、川崎善子、立石耕司、寺島康浩、柴沼均、酒井良忠、柱本照。
- Organizer
  第63回日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] 関節リウマチモデルマウスにおけるJAK阻害剤を用いた時間治療の検討2019
- Author(s)
  八重倉愛里沙、奥村郁美、金城健太、内田京、森井寛太、桶谷優斗、吉田幸祐、川崎善子、柴沼均、酒井良忠　、柱本照。
- Organizer
  第63回日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] JAK阻害剤が拓く最新リウマチ診療2019
- Author(s)
  柱本照
- Organizer
  第40回日本炎症・再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] 生物学的製剤治療が関節リウマチ患者白血球における時計遺伝子発現を変動させる2019
- Author(s)
  森井寛太、桶谷優斗、金城健太、内田京、奥村郁美、八重倉愛里沙、吉田幸祐、川崎善子、柴沼均、酒井良忠、柱本照。
- Organizer
  第63回日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] “Chronotherapy using Baricitinib attenuates Collagen-induced Arthritis in mice.”2019
- Author(s)
  Arisa Yaekura, Kanta Morii, Yuto Oketani, Ikumi Okumura, Kenta Kaneshiro, Kohsuke Yoshida, Yoshiko Kawasaki, Nao Shibanuma, Yoshitada Sakai, Akira Hashiramoto.
- Organizer
  米国リウマチ学会2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] 滑膜細胞におけるTNFα誘導性CCL2発現増加に対するヒストンアセチル化酵素と転写因子RORα/REV-ERBαの役割2019
- Author(s)
  奥村郁美、吉田幸祐、金城健太、内田京、八重倉愛里沙、桶谷優斗、森井寛太、立石耕司、寺島康浩、川崎善子、柴沼均、酒井良忠、柱本照。
- Organizer
  第63回日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] “Roles Of Histone Acetyltransferases CBP/p300 And Transcriptional Factor RORα/REV-ERBα Against TNFα-induced CCL2 Expression in RA-FLSs.”2019
- Author(s)
  Ikumi Okumura, Kohsuke Yoshida, Kenta Kaneshiro, Koto Uchida, Arisa Yaekura, Yuto Oketani, Kanta Morii, Koji Tateishi, Yasuhiro Terashima, Yoshiko Kawasaki, Nao Shibanuma, Yoshitada Sakai, Akira Hashiramoto.
- Organizer
  米国リウマチ学会2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] TNF阻害剤の基礎と臨床2019
- Author(s)
  柱本照
- Organizer
  第84回日本インターフェロン・サイトカイン学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] IL-6とTNFaは細胞周期調節因子を介して協調的に滑膜細胞増殖に関与する2018
- Author(s)
  金城健太、吉田幸祐、中井綾子、鈴木行人、内田京、橋本哲平、川崎善子、立石耕司、寺島康浩、中川夏子、柴沼均、酒井良忠、柱本照
- Organizer
  第62回日本リウマチ学会（東京）
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] TNF-αはc-Mycを介してリウマチ滑膜細胞のp27Kip発現を変化させる2018
- Author(s)
  金城健太、吉田幸祐、中井綾子、鈴木行人、内田京、橋本哲平、川崎善子、立石耕司、寺島康浩、中川夏子、柴沼均、酒井良忠、柱本照
- Organizer
  第62回日本リウマチ学会（東京）
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] IL-6 and TNF-a cooperate to modulate Cell Cycle of RA-FLS via Cyclin Dependent Kinase 6.2018
- Author(s)
  K. Kaneshiro, K. Yoshida, A. K. Uchida, T. Hashimoto, Y. Kawasaki, N. Tateishi, N. Terashima Y, Shibanuma, Y. Sakai, A. Hashiramoto.
- Organizer
  2018ACR/ARHP Annual Meeting (Chicago)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] 時計遺伝子Bmal1は細胞周期調節因子を介して関節リウマチ滑膜細胞の増殖能を制御する2018
- Author(s)
  内田京、吉田幸祐、金城健太、中井綾子、鈴木行人、橋本哲平、川崎善子、立石耕司、寺島康浩、中川夏子、柴沼均、酒井良忠、柱本照
- Organizer
  第62回日本リウマチ学会（東京）
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] IL-6は時計遺伝子を介して滑膜細胞に細胞死抵抗性をもたらす2018
- Author(s)
  鈴木行人、吉田幸祐、金城健太、中井綾子、内田京、橋本哲平、川崎善子、立石耕司、寺島康浩、中川夏子、柴沼均、酒井良忠、柱本照
- Organizer
  第62回日本リウマチ学会（東京）
- Data Source
  KAKENHI-PROJECT-18K08408
[Presentation] Interferon α causes SEE by expanding CD3+ CD4- CD8-double negative T cell (DN T cell).2010
- Author(s)
  Akiyama C, Honda E, Hashiramoto A, Felsher DW, shiozawa S
- Organizer
  American College of Rheumatology 74^<th> Annual Scientific Meeting, Atlanta
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] The variant of MHC class I polypeptide-related sequence (MICA) is a genetic risk factor for SLF independent of HLA-DRBI and modulates the behavior of NK cell via NKG2D.2010
- Author(s)
  shida K, Komai K, Shiozawa K, Mashida A, Horiuchi T, Tanaka Y, Nose M, Hashiramoto A,Shiozawa S
- Organizer
  American College of Rheumatology 74^<th> Annual Scientific Meeting, Atlanta
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Inhibition of c-Fos/AP-1 suppresses passive anti-collagen antibody-induced arthritis in mice. American College of Rheumatology2010
- Author(s)
  Mikami M, Aikawa Y, Hashiramoto A, Yamamoto M, Murao H, Chaki H, Narita H, Hirono S, Shiozawa S
- Organizer
  74^<th> Annual Scientific Meeting, Atlanta
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Inhibition of c-Fos/AP-1 suppresses passive anti-collagen antibody-induced arthritis in mice.2010
- Author(s)
  Mikami M, Aikawa Y, Hashiramoto A, et al.
- Organizer
  American College of Rheumatology 74th Annual Scientific Meeting
- Place of Presentation
  アトランタ(アメリカ)
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] A novel splicing regulatory mechanism in generating a truncated human death receptor 3 (DR3) gene product that contributes to the pathogenesis of rheumatoid arthritis.2010
- Author(s)
  Mizuhara M, Hashiramoto A, Yoshida K, Shiozawa S
- Organizer
  American College of Rheumatology 74^<th> Annual Scientific Meeting, Atlanta
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] A Novel splicing regulatory mechanism in generating a truncated human death receptor 3 (DR3) gene product that contributes to the pathogenesis of rheumatoid arthritis.2010
- Author(s)
  Mizuhara M, Hashiramoto A, Yoshida K, et al.
- Organizer
  American College of Rheumatology 74th Annual Scientific Meeting
- Place of Presentation
  アトランタ(アメリカ)
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] RA患者における血清低カルボキシル化オステオカルシン(ucOC)濃度の検討(第2報)2010
- Author(s)
  酒井良忠、柱本照、柴沼均、田中千尋、川崎善子、橋本哲平、黒坂昌弘、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 関節リウマチ患者における睡眠障害2010
- Author(s)
  真志田彩、塩沢和子、井上瞳、岩崎百合子、田中千尋、山根隆志、酒井良忠、橋本哲平、岡野隆一、柱本照、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] The sleep disturbance in patients with rheumatoid arthritis could be due to up-regulated c-Fos/AP-1 and Wee 1 kinase.2010
- Author(s)
  Shiozawa K, Hashiramoto A, Shiozawa S.
- Organizer
  The 2010 Annual European Congress of Rheumatology EULAR
- Place of Presentation
  ローマ(イタリア)
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Interferon α causes SLE by expanding CD3^+CD4^-CD8^+ double negative T cell (D N T Cell).2010
- Author(s)
  Akiyama C, Honda E, Hashiramoto A, et al.
- Organizer
  American College of Rheumatology 74th Annual Scientific Meeting
- Place of Presentation
  アトランタ(アメリカ)
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 関節リウマチ患者の睡眠障害に対するハーブ足浴の効果2010
- Author(s)
  大西瑠美、岩崎山田鈴子、真志田彩、田中千尋、柱本照、塩沢和子、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] The serum level of undercarboxylated osteocalcin (ucOC) in patients with rheumatoid arthritis-a high dose of predonisolone decrease the serum level of ucOC.2010
- Author(s)
  Sakai Y, Hashiramoto A, Hashimoto T, et al.
- Organizer
  American College of Rheumatology 74th Annual Scientific Meeting
- Place of Presentation
  アトランタ(アメリカ)
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Angiopoietin-1(Ang-1)バリアントの肺高血圧症への寄与の検討2010
- Author(s)
  真志田彩、柱本照、駒井浩一郎、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] MICA129Met/A9アリルはSLEに強く関与する2010
- Author(s)
  吉田幸祐、駒井浩一郎、塩沢和子、真志田彩、堀内孝彦、能勢眞人、柱本照、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] インターフェロン治療中断後に、ポリニューロパチーにて発症したクリオグロブリン血症の一例2010
- Author(s)
  橋本哲平、柱本照、川崎善子、岡野隆一、田中千尋、鍵谷真希、酒井良忠、柴沼均、郡山健治、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Place of Presentation
  兵庫県
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] MCTD患者におけるAng-1スプライシングバリアント誘導関連抗U1RNP抗体のエピトープ分析2010
- Author(s)
  小杉優佳、駒井浩一郎、船木省吾、塩沢和子、柱本照、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 日内リズムと関節炎2010
- Author(s)
  柱本照
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Contribution of MICA gene polymorphism to systemic lupus erythematosus in Japanese population.2010
- Author(s)
  吉田幸祐, 駒井浩一郎, 塩沢和子, 真志田彩, 柱本照, 塩沢俊一
- Organizer
  14^<th> International Congress of Immunology, Kobe
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] The variant of MHC class I polypeptide-related sequence (MICA) is a genetic risk factor for SLE independent of HLA-DRB1 and modulates the behavior of NK Cell Via NKG2D receptor.2010
- Author(s)
  Yoshida Y, Komai K, Hashiramoto A, et al.
- Organizer
  American College of Rheumatology 74th Annual Scientific Meeting
- Place of Presentation
  アンランタ(アメリカ)
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 関節リウマチ患者の睡眠の質.睡眠ポリグラフィーを用いて測定2010
- Author(s)
  西田みち子、塩沢和子、田中原良祐、村田美紀、山根隆志、田中千尋、葉乃彰、中川夏子、香山幸造、寺島康浩、松田茂、横山公信、居村茂明、真志田彩、柱本照、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] The serum level of undercarboxylated osteocalcin (ucOC) in patients with rheumatoid arthritis-a high dose of predonisolone decrease the serum level of ucOC.2010
- Author(s)
  Sakai Y, Hashiramoto A, Hashimoto T, Kawasaki Y, Tanaka C, Shiozawa S, Kurosaka M
- Organizer
  American College of Rheumatology 74^<th> Annual Scientific Meeting, Atlanta
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 当センターにおける関節リウマチ患者に対するアダリムマブの使用成績2010
- Author(s)
  柱本照、川崎善子、田中千尋、橋本哲平、鍵谷真希、岡野隆一、酒井良忠、柴沼均、郡山健治、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 抗UIRNP抗体及び炎症性サイトカインによるMCTD疾患関連Ang-1スプライスバリアント誘導2010
- Author(s)
  船木省吾、駒井浩一郎、小杉優佳、塩沢和子、柱本照、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 自己免疫性組織傷害の誘導におけるT細胞と免疫複合体の寄与の検討2010
- Author(s)
  積山賢、柱本照、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 当センターにおける新規関節リウマチ患者に対する治療成績2010
- Author(s)
  橋本哲平、柱本照、酒井良忠、川崎善子、鍵谷真希、田中千尋、柴沼均、岡野隆一、郡山健治、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] ハーブ足浴が wee1 kinase発現に及ぼす影響2010
- Author(s)
  田中千尋、塩沢和子、岩崎百合子、宮崎よりの、西田みち子、真志田彩、柱本照、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 新規低分子c-Fos/AP-1阻害剤T-5224の破骨細胞分化・骨吸収に対する作用2010
- Author(s)
  村尾英俊、相川幸彦、柱本照、広野修一、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 関節リウマチ患者の睡眠障害に対するハーブ足浴の効果-アクチグラフを用いた検討-2010
- Author(s)
  西井佐織、岩崎百合子、宮崎よりの、西田みち子、真志田彩、田中千尋、柱本照、塩沢和子、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 関節リウマーブ足浴の効果2010
- Author(s)
  宮崎よりの、岩崎百合子、清水みえ子、山田鈴子、真志田彩、柱本照、塩沢和子、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 関節リウマチ患者の血液学的マーカーに対するハーブ足浴の効果2010
- Author(s)
  岩崎百合子、宮崎よりの、真志田彩、柱本照、塩沢和子、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 関節リウマチの疾患遺伝子変異型DR3のイントロン5にスプライシング調節蛋白が結合する2010
- Author(s)
  水原賢、柱本照、吉田幸祐、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] A small molecule c-Fos/AP-1 inhibitor T-5224 inhibits osteoclastogenesis and Bone resorption.2010
- Author(s)
  Murao H, Aikawa Y, Hashiramoto A, Yamamoto T, Chaki H, Narita H, Hirono S, Shiozawa S
- Organizer
  American College of Rheumatology 74^<th> Annual Scientific Meeting, Atlanta
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Anti-UIC autoantibody specifically interferes with the UIRNP-mediated splicing of Angiopoietin-1 (Angl) gene and induces functionally defective Ang-1/ins variant in the patients with MCTD.2010
- Author(s)
  Kosugi Y, Komai K, Funaki S, Mashida A, Shiozawa K, Hashiramoto A, Shiozawa S
- Organizer
  American College of Rheumatology 74^<th> Annual Scientific Meeting, Atlanta
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Death Receptor-3ノックアウトマウスにおける細胞死誘導とNF-κBシグナル活性化の検討2010
- Author(s)
  川崎善子、柱本照、塩沢俊一
- Organizer
  第54回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 抗TNFα抗体はCry欠損マウスの実験的関節炎を抑制する2009
- Author(s)
  本田枝璃子、積山賢、吉田幸祐、駒井浩一郎、柱本照、塩沢俊一
- Organizer
  第53回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] コクサッキーA7ウイルス感染症を契機に発症した成人スチル病の一例2009
- Author(s)
  柱本照、酒井良忠、川崎善子、田中千尋、黒坂昌弘、塩沢俊一
- Organizer
  第53回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 新規低分子c-Fos/AP-1阻害剤T-5224のマウス抗H型コラーゲン抗体誘発関節炎(CAIA)に対する抑制作用2009
- Author(s)
  相川幸彦、柱本照、広野修一、塩沢俊一
- Organizer
  第53回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Immune complex is repuired but insufficient for autoimmune tissue injury : essential role of effector CD8+T Cell.2009
- Author(s)
  積山賢, 柱本照, 塩沢俊一
- Organizer
  American College of Rheumatology 73^<st> Annual Scientific Meeting
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Angiopoietin-1(Ang-1)バリアントによるTie2活性化増強を介する肺高血圧症への寄与の検討2009
- Author(s)
  真志田彩、柱本照、塩沢俊一
- Organizer
  第53回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 抗原の繰り返し投与により成立したRAG発現自己応答性CD4+T細胞が自己抗体産生を誘導する2009
- Author(s)
  積山賢、宮崎由実、柱本照、塩沢俊一
- Organizer
  第53回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] MCTD患者血清中抗UIRNP自己抗体による血管新生因子Angiopoietin-1(Ang-1)スプライシング干渉2009
- Author(s)
  船木省吾、駒井浩一郎、小杉優佳、本田枝璃子、塩沢和子、柱本照、塩沢俊一
- Organizer
  第53回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Molecular clock modulates arthritis.2009
- Author(s)
  塩沢和子, 柱本照, 塩沢俊一
- Organizer
  2009 EULAR (10^<th> Annual Congress of the European League against Rheumatism), Copenhagen
- Place of Presentation
  Denmark
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] SLE患者における抗Sm抗体と血管新生因子Angiopoietin-1(Ang-1)スプライシングバリアントの相関解析2009
- Author(s)
  小杉優佳、駒井浩一郎、船木省吾、塩沢和子、柱本照、塩沢俊一
- Organizer
  第53回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] バリアントAngiopoietin-1(Ang-1)の肺動脈血管内皮および平滑筋細胞におけるERKシグナル伝達増強を介する肺高血圧症への寄与の研究2009
- Author(s)
  川添高子、柱本照、駒井浩一郎、塩沢俊一
- Organizer
  第53回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] MCTD患者における血管新生因子Angiopoietin-1(Ang-1)mRNAスプライシング干渉要因としての抗UIRNP抗体2009
- Author(s)
  駒井浩一郎、船木省吾、塩沢和子、柱本照、塩沢俊一
- Organizer
  第53回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 関節リウマチ患者における血清低カルボキシル化オステオカルシン(ucOC)濃度の検討2009
- Author(s)
  酒井良忠、柱本照、川崎善子、田中千尋、黒坂昌弘、塩沢俊一
- Organizer
  第53回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 関節リウマチ患者の睡眠障害の研究2009
- Author(s)
  田中千尋、山根隆志、横山公信、松田茂、村田美紀、寺島康浩、香山幸造、阿部修治、中川夏子、吉原良祐、田中泰史、塩沢和子、柱本照、塩沢俊一
- Organizer
  第53回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 抗原のクロスプレゼンテーションにより活性化したCD8+T細胞が自己免疫性組織傷害を誘導する2009
- Author(s)
  積山賢、柱本照、塩沢俊一
- Organizer
  第53回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 変異型MICAはNK細胞のIFNγ産生を強く誘導する2009
- Author(s)
  吉田幸祐、真志田彩、駒井浩一郎、柱本照、田平知子、堀内孝彦、能勢眞人、塩沢和子、塩沢俊一
- Organizer
  第53回日本リウマチ学会学術総会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Variant angiopoientin-1 with ^<269>Gly insertion contributes to the pathogenesis of pulmonary hypertension; a novel mechanism for stimulating pulmonary smooth muscle cell growth.2009
- Author(s)
  真志田彩, 柱本照, 川添高子, 駒井浩一郎, 塩沢俊一
- Organizer
  American College of Rheumatology 73^<st> Annual Scientific Meeting
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Variant Angiopoietin-1 with ^<269>Gly insertion contributes the pathogenesis of pulmonary hypertension by regulates the function of human pulmonary artery endothelial cells2009
- Author(s)
  Mashida A, Hashiramoto A, et al.
- Organizer
  American College of Rheumatology 73^<rd> Annual Scientific Meeting
- Place of Presentation
  フィラデルフィア、米国
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 関節炎が概日リズムに及ぼす影響2009
- Author(s)
  柱本照
- Organizer
  第19回日本リウマチ学会近畿支部学術集会
- Place of Presentation
  毎日新聞社オーバルホール(大阪府)
- Year and Date
  2009-09-03
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Full maturation of CD8+ T cell via antigen cross presentation into IFN- γ -producing effector is prerequisite to the induction of autoimmune tissue injury.2008
- Author(s)
  積山賢, 柱本照, 塩沢俊一
- Organizer
  American College of Rheumatology 72^<st> Annual Scientific Meeting
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 新規低分子c-Fos/AP-1阻害剤T-5224の滑膜細胞伸展及び破骨細胞活性化に対する作用2008
- Author(s)
  相川幸彦、柱本照、広野修一、塩沢俊一
- Organizer
  第52回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Arthritis modulates biological clock : cry directly regulates the transactivation of TNF-alpha gene.2008
- Author(s)
  柱本照, 吉田幸祐, 積山賢, 山根隆志, 駒井浩一郎, 塩沢俊一
- Organizer
  American College of Rheumatology 72^<st> Annual Scientific Meeting
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] CD8+T細胞欠損マウスへの抗原の繰り返し投与による自己免疫疾患の解析2008
- Author(s)
  積山賢、柱本照、塩沢俊一
- Organizer
  第52回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Molecular clock modulates arthritis2008
- Author(s)
  Hashiramoto A, Shiozawa s.
- Organizer
  Asia Pacific League of Associations for Rheumatology
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] リウマチ滑膜細胞上のVLA-5(a5b1インテグリン)はAngiopoietin-1のシグナル伝達に関与する2008
- Author(s)
  春名真徳、三浦靖史、大沼健一郎、駒井浩一郎、柱本照、塩沢和子、黒坂昌弘、塩沢俊一
- Organizer
  第52回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 抗原の繰り返し投与によるCD8+T細胞の活性化と腎炎の関与の検討2008
- Author(s)
  積山賢、柱本照、塩沢俊一
- Organizer
  第52回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Hsp 90 modulates actin filament rearrangement in rheumatoid synovial cell via Ilk-dependent pathway.2008
- Author(s)
  Hashiramoto A, Akiyama c, Onuma K, Yoshida K, Nakagawa N, Komai K, Shiozawa K, Shiozawa S.
- Organizer
  American College of Rheumatology 72^<st> Annual Scientific Meeting.
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Molecular clock modulates arthritis.2008
- Author(s)
  柱本照, 塩沢俊一
- Organizer
  Int J Rheum Asia Pacific League of Associations for Rheumatology
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 初診時抗CCP抗体陰性関節リウマチ患者の追跡調査2008
- Author(s)
  山根隆志、田中泰史、塩沢和子、柱本照、塩沢俊一
- Organizer
  第52回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 当科におけるレフルミドの長期成績と中止事象の検討2008
- Author(s)
  酒井良忠、三浦靖史、立石耕司、高橋完靖、柱本照、塩沢俊一、黒坂昌弘
- Organizer
  第52回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] SEBの繰り返し投与によるT細胞アネルギーの破綻を誘導するエフェクター分子の同定2008
- Author(s)
  土井愛、積山賢、柱本照、塩沢俊一
- Organizer
  第52回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 関節リウマチ患者の睡眠障害2008
- Author(s)
  山根隆志、柱本照、塩沢和子、塩沢俊一
- Organizer
  第52回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 抗原の繰り返し投与による自己免疫誘導の際のクロスプレゼンテーションに関与する分子2008
- Author(s)
  宮崎由実、積山賢、柱本照、塩沢俊一
- Organizer
  第52回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 269Gly(+)型Angiopoietin-1(Ang-1)は肺動脈血管内皮と平滑筋の共培養においてERKのリン酸化を強く引き起こす2008
- Author(s)
  川添高子、柱本照、駒井浩一郎、塩沢俊一
- Organizer
  第52回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 時計遺伝子欠損マウスにおける実験的関節炎の増悪には炎症性サイトカインTNFaが関与する2008
- Author(s)
  吉田幸祐、柱本照、山恨隆志、積山賢、駒井浩一郎、塩沢俊一
- Organizer
  第52回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Induction of autoantibody and autoimmune tissue injury is differentially regulated by CD4+ and CD8+ T cells.2008
- Author(s)
  積山賢, 柱本照, 塩沢俊一
- Organizer
  American College of Rheumatology 72^<st> Annual Scientific Meeting
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 滑膜細胞遊走能に関するintegrin-linked kinase(ILK)の役割の検討2008
- Author(s)
  秋山千絵莉、柱本照、大沼健一郎、三浦靖史、香山幸造、阿部修治、中川夏子、塩沢和子、黒坂昌弘、塩沢俊一
- Organizer
  第52回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Arthritis modulates biological clock : cry directly regulates the transactivation of TNF-alpha gene.2008
- Author(s)
  Hashiramoto A, Yoshida K, Tsumiyama K, Yamane T, Komai K, Shiozawa S.
- Organizer
  American College of Rheumatology 72^<st> Annual Scientific Meeting.
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Hsp 90 modulates actin filament rearrangement in rheumatoid synovial cell via Ilk-dependent pathway.2008
- Author(s)
  柱本照, 秋山千絵莉, 大沼健一郎, 吉田幸祐, 中川夏子, 駒井浩一郎, 塩沢和子, 塩沢俊一
- Organizer
  American College of Rheumatology 72^<st> Annual Scientific Meeting
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Variant angiopoietin-1 (Ang-1) with ^<269>gly insertion induces hyperproliferation of pulmonary endothelial cell : possible contribution to pulmonary hypertension (PH) in MCTD and SSc.2008
- Author(s)
  川添高子, 柱本照, 駒井浩一郎, 塩沢俊一
- Organizer
  American College of Rheumatology 72^<st> Annual Scientific Meeting
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 関節リウマチ患者を対象としたMTX治療効果に関するProspective Study2008
- Author(s)
  柱本照、塩沢和子、田中泰史、吉原良祐、村田美紀、山根隆志、寺島康浩、香山幸造、中川夏子、三浦靖史、三枝康宏、塩沢俊一
- Organizer
  第52回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] VLA-5 is alternative receptor for angiopoietin-1/tie2 signaling via MAP kinase in rheumatoid synovial cells.2008
- Author(s)
  Miura Y, Haruna M, Onuma K, Komai K, Hashiramoto A, Shiozawa K, Kurosaka M, Shiozawa S
- Organizer
  Asia Pacific League of Associations for Rheumatology
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] 実験的関節炎誘導による概日リズムの障害2008
- Author(s)
  柱本照、山根隆志、積山賢、吉田幸祐、駒井浩一郎、塩沢俊一
- Organizer
  第52回日本リウマチ学会学術総会
- Data Source
  KAKENHI-PROJECT-20591170
[Presentation] Variant Death Receptor 3 Gene, Genetically Associated with Rheumatoid Arthritis Inhibit TL1A-induced Splenocyte Signaling and CD4/8 Cell Subset in Thymus2007
- Author(s)
  Kawazoe T, Hashiramoto A, Tsumiyama K, Shiozawa S,
- Organizer
  American College of Rheumatology 71th Annual Scientific Meeting
- Place of Presentation
  Boston
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] RAにおける睡眠障害と関節炎2007
- Author(s)
  柱本照
- Organizer
  第17回日本リウマチ学会近畿支部学術集会
- Place of Presentation
  大阪
- Year and Date
  2007-09-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] 新規低分子c-FOS/AP-1阻害剤T-5224のマウスII型コラーゲン誘発関節炎(CIA)に対する予防効果2006
- Author(s)
  塩沢俊一、柱本照、相川幸彦、広野修一
- Organizer
  第51回日本リウマチ学会学術総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] Anti-CCP2 assay accurately predicts future development of rheumatoid arthritis as early as 3 months from onset of arthritic symptoms.2006
- Author(s)
  Yamane T, Shiozawa K, Hashiramoto A, Tanaka Y, Tsumiyama K, Miura Y, Shiozawa S.
- Organizer
  American College of Rheumatology 70th Annual Scientific Meeting
- Place of Presentation
  Washington, DC
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] RA疾患遺伝子感受性候補ANG-1の機能2006
- Author(s)
  柱本照
- Organizer
  第51回日本リウマチ学会学術総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] Disruption of circadian rhythm aggravates experimental arthritis:study in cry gene-knockout mice.2006
- Author(s)
  Yamane T, Hashiramoto A, Tsumiyama K, Okamura H, Shiozawa S.
- Organizer
  American College of Rheumatology 70th Annual Scientific Meeting
- Place of Presentation
  Washington, DC
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] 睡眠障害Cry遺伝子欠損マウスでは実験的関節炎が増悪する2006
- Author(s)
  山根隆志、柱本照、積山賢、塩沢俊一
- Organizer
  第50回日本リウマチ学会学術総会
- Place of Presentation
  長崎
- Year and Date
  2006-04-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] Once-anergized T cell in autoimmune-prone MRL/1pr mice cannot be reactivated from anergy and generate autoantibodies after repeated priming with exogenous antigen.2006
- Author(s)
  Tsumiyama K, Isaka S, Hashiramoto A, Shiozawa S.
- Organizer
  American College of Rheumatology 70th Annual Scientific Meeting
- Place of Presentation
  Washington, DC
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] A novel small molecule AP-1 inhibitor T-5224 resolves mouse type II collagen-induced arthritis in a c-Fos/AP-1-specific fashion.2006
- Author(s)
  Aikawa Y, Morimoto K, Yamamoto T, Chaki H, Hashiramoto A, Narita H, Hirono S, Shiozawa S.
- Organizer
  American College of Rheumatology 70th Annual Scientific Meeting
- Place of Presentation
  Washington, DC
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] 関節炎と概日リズム-時計遺伝子欠損マウスで実験的関節炎は増悪する2006
- Author(s)
  山根隆志、柱本照、積山賢、塩沢俊一
- Organizer
  第51回日本リウマチ学会学術総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] Disruption of circadian rhythm aggravates experimental arthritis: study in cry gene-knockout mice2006
- Author(s)
  Yamane, T, Hashiramoto, A, Tsumiyama, K, Okamum, H, Shiozawa, S
- Organizer
  American College of Rheumatology 70th Annual Scientific Meeting
- Place of Presentation
  Washington, DC
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] 関節リウマチ疾患遺伝子変異型dr3 ドランスジェニックマウス脾細胞ではNFkB活性化が抑制される2006
- Author(s)
  川添高子、柱本照、三浦靖史、塩沢俊一
- Organizer
  第51回日本リウマチ学会学術総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] Mutant type human death receptor 3 acts on the onset of collagen-induced arthritis.2006
- Author(s)
  Hashiramoto A, Tanaka K, Nagahama T, Miura Y, Shiozawa S.
- Organizer
  American College of Rheumatology 70th Annual Scientific Meeting
- Place of Presentation
  Washington, DC
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] 新規低分子c-FOS/AP-1阻害剤T-5224の治療的投与によるマウスII型コラーゲン誘発関節炎(CIA)の抑制2006
- Author(s)
  塩沢俊一、柱本照、相川幸彦、広野修一
- Organizer
  第51回日本リウマチ学会学術総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] Heat Schock Protein90はインテグリンを介して関節リウマチ滑膜細胞のシグナル伝達に作用する2006
- Author(s)
  柱本照、川添高子、吉田幸祐、阿部修治、中川夏子、三枝康宏、塩沢和子、石川斎、塩沢俊一
- Organizer
  第51回日本リウマチ学会学術総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] Once-anergized T cell in autoimmune-prone MRLIpr mice cannot be reactivated from anergy and generate autoantibodies after repeated priming with exogenous antigen
- Author(s)
  Tsumiyama, K, Isaka, S, Hashiramoto, A, Shiozawa, S
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] Anti-CCP2 assay accurately predicts future development of rheumatoid arthritis as early as 3 months from onset of arthritic symptoms
- Author(s)
  Yamane, T, Shiozawa, K, Hashiramoto, A, Tanaka, Y, Tsumiyama, K, Miura, Y, Shiozawa, S
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] Mutant type human death receptor 3 acts on the onset of collagen-induced arthritis
- Author(s)
  Hashiramoto, A, Tanaka, K, Nagahama, T, Miura, Y, Shiozawa, S
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591110
[Presentation] A novel small molecule AP-1 inhibitor T-5224 resolves mouse type II collagen-induced arthritis in a c-Fos/AP-1-specific fashion
- Author(s)
  Aikawa, Y, Morimoto, K, Yamamoto, T, Chaki, H, Hashiramoto, A, Narita, H, Hirono, S, Shiozawa, S
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591110

1. MIURA Yasushi (60346244)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
2. KOMAI Koichiro (40304117)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. 吉田幸祐 (80452499)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
4. SHIOZAWA Shunichi (40154166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ISHIKAWA Hitoshi (30107958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 塚本康夫 (30031149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 村田美紀 (70346245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 古和久朋 (60396728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. TSUMIYAMA Ken

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
10. KAWAZOE Takako

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. 塩澤俊一

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
12. 石川斉

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 植木重治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 金城健太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HASHIRAMOTO AKIRA 柱本 照

柱本 照 ハシラモト アキラ

Hashiramoto Akira 柱本 照

HASHIRAMOTO Akira 柱本 照

Research Projects

Research Products

Co-Researchers

認知症における新規血中バイオマーカーの探索 ～炎症誘導性マイクロRNAの意義～

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Project Period (FY)

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Tef 遺伝子改変マウスを用いた関節リウマチ病態解析と創薬へのアプローチPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Development of chronotherapy for rheumatoid arthritis targeting the clock gene Bmal1.Principal Investigator

Principal Investigator

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Review Section

Research Institution

Sleep disturbance and related changes of circadian rhythm in patients with rheumatoid arthritis.Principal Investigator

Principal Investigator

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Research Field

Research Institution

Disruption of circadian rhythm aggravates experimental arthritis: study in cry gene-knockout mice.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research of pathogenesis of rheumatoid arthritis by TL1A knock out mice

Principal Investigator

Project Period (FY)

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Research of rheumatoid arthritis using Dbl knock-out micePrincipal Investigator

Principal Investigator

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Research Institution

Studies on the causative disease gene in autoimmunity and rheumatoid arthritis

Principal Investigator

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Research Institution

[Journal Article] Initiation of belimumab with higher daily prednisolone is effective for rapid glucocorticoid reduction: A 96-week retrospective study2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The clock gene Bmal1 controls inflammatory mediators in rheumatoid arthritis fibroblast-like synoviocytes2024

Author(s)

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DOI

Data Source

[Journal Article] A case of chronic eosinophilic pneumonia associated with rheumatoid arthritis in Glucocorticoid-free remission with JAK inhibitor: A case report.2023

Author(s)

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Data Source

[Journal Article] A case of chronic eosinophilic pneumonia associated with rheumatoid arthritis in glucocorticoid-free remission with JAK inhibitor: A case report2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tocilizumab suppresses NF-kappa B activation via toll-like receptor 9 signaling by reducing cell-free DNA in rheumatoid arthritis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased Circulating Cell-Free DNA in Eosinophilic Granulomatosis With Polyangiitis: Implications for Eosinophil Extracellular Traps and Immunothrombosis2022

HASHIRAMOTO AKIRA 柱本照

柱本照ハシラモトアキラ

Hashiramoto Akira 柱本照

HASHIRAMOTO Akira 柱本照

認知症における新規血中バイオマーカーの探索～炎症誘導性マイクロRNAの意義～