Imasawa Toshiyuki 今澤俊之

… Alternative Names

今澤俊之イマサワトシユキ

IMASAWA Toshiyuki 今澤俊之

Less

Researcher Number	80348276
Other IDs
Affiliation (Current)	2025: 順天堂大学, 大学院医学研究科, 客員教授 2025: 独立行政法人国立病院機構千葉医療センター千葉東病院(臨床研究部), 統括診療部, 部長 2025: 独立行政法人国立病院機構千葉医療センター千葉東病院(臨床研究部), 腎ミトコンドリア研究室, 室長
Affiliation (based on the past Project Information) *help	2024: 独立行政法人国立病院機構(千葉東病院臨床研究部), 腎ミトコンドリア研究室, 室長 2016 – 2022: 独立行政法人国立病院機構(千葉東病院臨床研究部), 腎センター, 腎センター長 2015: 独立行政法人国立病院機構(千葉東病院臨床研究部), その他部局等, その他 2014: 独立行政法人国立病院機構(千葉東病院臨床研究センター), その他部局等, その他 2012 – 2013: 独立行政法人国立病院機構(千葉東病院臨床研究センター), その他部局等, 研究員 … More 2010: 独立行政法人国立病院機構千葉東病院, 臨床研究センター, 室長・内科医長 2006: 国立病院機構千葉東病院, 臨床研究センター免疫病理研究部免疫機構研究室, 室長 2005: 独立行政法人国立病院機構(千葉東病院臨床研究センター), 免疫病理研究部免疫機構研究室室長 2004: 独立行政法人国立病院機構千葉東病院, 統括診療部第一診療部, 内科医師 2003: 埼玉医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related Except Principal Investigator Human pathology
Keywords	Principal Investigator ミトコンドリア / 糖尿病性腎症 / 低出生体重 / 糸球体上皮細胞 / 鉄 / 近位尿細管細胞 / トランスクリプトーム / バイオインフォマティクス解析 / 腎組織 / トランスクリプトーム解析 … More / 結節病変 / 糖尿病性腎臓病 / 病理学 / ミトコンドリア病 / DoHAD / 巣状分節性糸球体硬化症 / Mitochondria / エネルギー代謝 / 巣状分節状糸球体硬化症 / ハブ毒 / メサンギウム細胞 / 内皮細胞 / 老化腎 / 腎炎 / 糸球体再生 / 腎移植 / プロテオーム解析 / 蛋白質翻訳後修飾 / 腎再生 / IgA腎症 / 骨髄 / 幹細胞 / 糸球体再構築 / 糸球体修復 … More Except Principal Investigator 病理学 / 予後 / 腎生検 / 病理 / 糖尿病性腎症 Less

The exploration of the effects of iron deficiency on mitochondrial function in renal proximal tubular epithelial cells and its underlying mechanismsPrincipal Investigator
- Principal Investigator
  
  今澤俊之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  National Hospital Organization Chiba-East-Hospital
Transcriptome analysis of kidney biopsied tissues of diabetic kidney diseasePrincipal Investigator
- Principal Investigator
  
  Imasawa Toshiyuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  National Hospital Organization Chiba-East-Hospital
The role of mitochondria in the pathogenesis of low birth weight-related nephropathyPrincipal Investigator
- Principal Investigator
  
  Imasawa Toshiyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  National Hospital Organization Chiba-East-Hospital
Research for investigation of pathogenesis of nephropathy in low-birth-weight individualsPrincipal Investigator
- Principal Investigator
  
  Imasawa Toshiyuki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Clinical research Center, Chiba-East National Hospital, National Hospital Organization
A pathologic and clinical study based on renal biopsies in diabetic nephropathy
- Principal Investigator
  
  KITAMURA Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Clinical research Center, Chiba-East National Hospital, National Hospital Organization
糸球体再構築促進による慢性糸球体疾患の組織修復治療法の開発-腎移植法を用いて-Principal Investigator
- Principal Investigator
  
  今澤俊之
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Clinical research Center, Chiba-East National Hospital, National Hospital Organization
骨髄由来細胞による糸球体再構築機序の解明とその臨床応用への試みPrincipal Investigator
- Principal Investigator
  
  今澤俊之
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Clinical research Center, Chiba-East National Hospital, National Hospital Organization
  Saitama Medical University

[Book] 「腎と透析」ベッドサイド検査事典「遺伝学的検査：ミトコンドリア異常症」2018
- Author(s)
  今澤俊之
- Total Pages
  3
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-16K09638
[Book] 医学のあゆみ（特集：ポドサイト障害-腎障害における新たな視点）2018
- Author(s)
  今澤俊之
- Total Pages
  5
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-16K09638
[Journal Article] High glucose repatterns human podocyte energy metabolism during differentiation and diabetic nephropathy2017
- Author(s)
  Toshiyuki Imasawa, Emilie Obre, Nad`ege Bellance, Julie Lavie,Tomoko Imasawa,Claire Rigothier, Yahsou Delmas, Christian Combe, Didier Lacombe, Giovanni Benard, St´ephane Claverol, Marc Bonneu, Rodrigue Rossignol
- Journal Title
  
  FASEB J
  
  Volume: 31 Issue: 1 Pages: 294-307
- DOI
  10.1096/fj.201600293r
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09638
[Journal Article] 7501 T>A mitochondrial DNA variant in a patient with glomerulosclerosis2014
- Author(s)
  Imasawa T (corresponding author), Tanaka M, Yamaguchi Y, Nakazato T, Kitamura H, Nishimura M.
- Journal Title
  
  Ren Fail
  
  Volume: 36 Issue: 9 Pages: 1461-1465
- DOI
  10.3109/0886022x.2014.945181
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591222, KAKENHI-PROJECT-25242062
[Journal Article] Pathological similarities between low birth weight-related nephropathy and nephropathy associated with mitochondrial cytopathy2014
- Author(s)
  Imasawa T (corresponding author), Tanaka M, Maruyama N, Kawaguchi T, Yamaguchi Y, Rossignol R, Kitamura H, Nishimura M
- Journal Title
  
  Diagn Pathol
  
  Volume: 9 Issue: 1 Pages: 181-181
- DOI
  10.1186/s13000-014-0181-0
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591222, KAKENHI-PROJECT-25242062
[Journal Article] Hemodialysis patients born with a low birth weight should have a different time course of kidney diseases than those born with a normal birth weight.2013
- Author(s)
  Imasawa T(corresponding author), Fukuda N, Hirose S, Kato N, Shinya Suganuma5, Yamamoto R, Kimura H, Kadomura M, Nishimura M, Yoshimura M, Ikei S
- Journal Title
  
  Ther Apher Dial
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591222
[Journal Article] Podocyte energy metabolism and glomerular diseases.2013
- Author(s)
  Imasawa T (corresponding author), Rossignol R
- Journal Title
  
  Int J Biochem Cell Biol.
  
  Volume: 45 Issue: 9 Pages: 2109-2118
- DOI
  10.1016/j.biocel.2013.06.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591222
[Journal Article] Unbalanced expression of sphingosine 1-phosphate receptors in diabetic nephropathy.2010
- Author(s)
  Imasawa T (corresponding author), Kitamura H, Ohkawa R, Satoh Y, Miyashita A, Yatomi Y
- Journal Title
  
  Exp Toxicol Pathol 62(1)
  
  Pages: 53-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590360
[Journal Article] Unbalanced expression of sphingosine 1-phosphate receptors in diabetic nephropathy2010
- Author(s)
  Imasawa T
- Journal Title
  
  Exp Toxicol Pathol. 62
  
  Pages: 53-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590360
[Journal Article] Blockade of sphingosine 1-phosphate receptor 2 signaling attenuates streptozotocin-induced apoptosis of pancreatic beta-cells2010
- Author(s)
  Imasawa T
- Journal Title
  
  Biochem Biophys Res Commun 392
  
  Pages: 201-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590360
[Journal Article] Unbalanced expression of sphingosine 1-phosphate receptors in diabetic nephropathy2009
- Author(s)
  Imasawa T
- Journal Title
  
  Exp Toxicol Pathol (Epub of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590360
[Journal Article] Accelerated tubular cell senescence in SMP30 knockout mice2006
- Author(s)
  Yumura W, Imasawa T (corresponding author) et al.
- Journal Title
  
  Histol Histopathol 21
  
  Pages: 1151-1156
- Data Source
  KAKENHI-PROJECT-17790559
[Journal Article] Accelerated tubular cell senescence in SMP30 knockout mice2006
- Author(s)
  Yumura W, Imasawa T (corresponding author) et al.
- Journal Title
  
  Histol Histopathol (in press)
- Data Source
  KAKENHI-PROJECT-17790559
[Journal Article] Citrullination preferentially proceeds in glomerular Bowman's capsule and increases in obstructive nephropathy2005
- Author(s)
  Feng D, Imasawa T (corresponding author). et al.
- Journal Title
  
  Kidney Int (in press)
- Data Source
  KAKENHI-PROJECT-15790436
[Journal Article] 抗老化に向けた組織再生能活性化2004
- Author(s)
  今澤俊之
- Journal Title
  
  基礎老化研究 28
  
  Pages: 9-13
- Data Source
  KAKENHI-PROJECT-15790436
[Journal Article] Roles of bone marrow cells in glomerular diseases2003
- Author(s)
  Imasawa T(corresponding author)
- Journal Title
  
  Clin Exp Nephrol 7
  
  Pages: 179-185
- NAID
  10011993640
- Data Source
  KAKENHI-PROJECT-15790436
[Presentation] Exploration of prognostic factors in diabetic nephropathy with nodular lesion using transcriptome analysis of human kidney tissues2023
- Author(s)
  Toshiyuki Imasawa, Hiroyuki Unoki-Kubota, Daishi Hirano, Hiroshi Kitamura, Yasushi Kaburagi
- Organizer
  第60回　European Renal Association Congress ERA 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08741
[Presentation] シンポジウム3　腎臓研究の最前線「多層的Omics解析によるCKD研究」2021
- Author(s)
  今澤俊之、北村博司、平野大志、鏑木康志、久保田浩之
- Organizer
  第51回日本腎臓学会東部学術大会
- Data Source
  KAKENHI-PROJECT-19K08741
[Presentation] シンポジウム6　腎診療におけるビッグデータ：何のために何ができる？「腎疾患における多層的オミックス解析研究の展望」2020
- Author(s)
  今澤俊之、北村博司、鏑木康志、久保田浩之
- Organizer
  第50回日本腎臓学会東部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08741
[Presentation] 教育講演5　「糖尿病性腎臓病の rapid decliner の病態を理解する」2020
- Author(s)
  今澤俊之
- Organizer
  第50回日本腎臓学会東部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08741
[Presentation] Metabolic Remodeling of Podocytes in Hyperglycemia2016
- Author(s)
  Toshiyuki Imasawa, Emilie Obre, Rodrigue Rossignol
- Organizer
  XVIII International Congress on Nutrition and Metabolism in Renal Disease (ICRNM2016)
- Place of Presentation
  Okinawa,Japan
- Year and Date
  2016-04-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591222
[Presentation] Reduced mitochondrial energy production in the kidney induces focal segmental glomerulosclerosis in low-birth-weight rats at adulthood2015
- Author(s)
  Imasawa T, Rossignol R
- Organizer
  48th Annual Meeting, The American Society of Nephrology
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591222
[Presentation] 低出生体重と腎障害-ミトコンドリア機能異常の関与-2015
- Author(s)
  今澤　俊之
- Organizer
  第45回日本腎臓学会東部学術大会
- Place of Presentation
  東京
- Year and Date
  2015-10-02
- Invited
- Data Source
  KAKENHI-PROJECT-24591222
[Presentation] II型糖尿病性腎症の病理組織パラメーターは臨床像を反映し、かつ予後予測を可能とする2010
- Author(s)
  石橋亮一、今澤俊之、首村守俊、祖山暁子、関直人、中里毅、西村元伸、北村博司
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590360
[Presentation] 糖尿病性腎症における組織像と血尿、網膜症との相互関係に関する検討2009
- Author(s)
  北村博司、今澤俊之、祖山暁子、関直人、首村守俊、西村元伸
- Organizer
  第52回日本腎臓学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590360
[Presentation] 糖尿病性腎症における病理像と臨床パラメーターの相関についての検討2008
- Author(s)
  今澤俊之
- Organizer
  第51回日本腎臓学会総会
- Place of Presentation
  福岡市
- Year and Date
  2008-05-31
- Data Source
  KAKENHI-PROJECT-20590360
[Presentation] ラット糖尿病性腎症糸球体におけるスフィンゴシリン1リン酸受容体発現パターンの変化2008
- Author(s)
  今澤俊之
- Organizer
  第51回日本腎臓学会総会
- Place of Presentation
  福岡市
- Year and Date
  2008-05-31
- Data Source
  KAKENHI-PROJECT-20590360
[Presentation] 厳格な管理が臨床的著理学的変化を伴った糖尿病性腎症の1例2008
- Author(s)
  関直人、北村博司、祖山暁子、今澤俊之、首村守俊、西村元伸
- Organizer
  第38回日本腎臓学会東部学術集
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590360
[Presentation] 病理組織像からみた糖尿病性腎症の予後2008
- Author(s)
  北村博司、西村元伸、関直人、祖山暁子、首村守俊、城謙輔、今澤俊之
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-20590360
[Presentation] 糖尿病性腎症における病理像と臨床パラメターの相関についての検討2008
- Author(s)
  今澤俊之、西村元伸、関直人、祖山暁子、首村守俊、中里毅、北村博司
- Organizer
  第51回日本腎臓学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20590360
[Presentation] ラット糖尿病性腎症糸球体におけるスフィゴシン1リン酸受容体発現パターンの変化2008
- Author(s)
  12.今澤俊之、北村博司、大川龍之介、佐藤優美子、小池健太郎、矢冨裕
- Organizer
  第51回日本腎臓学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20590360

1. YAMAGUCHI Yutaka

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. KITAMURA Hiroshi (40287701)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. NISHIMURA Motonobu (60443090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. TANAKA Masashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. Rossignol Rodrigue

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Imasawa Toshiyuki 今澤 俊之

今澤 俊之 イマサワ トシユキ

IMASAWA Toshiyuki 今澤 俊之

Research Projects

Research Products

Co-Researchers

The exploration of the effects of iron deficiency on mitochondrial function in renal proximal tubular epithelial cells and its underlying mechanismsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Transcriptome analysis of kidney biopsied tissues of diabetic kidney diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of mitochondria in the pathogenesis of low birth weight-related nephropathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research for investigation of pathogenesis of nephropathy in low-birth-weight individualsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A pathologic and clinical study based on renal biopsies in diabetic nephropathy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

糸球体再構築促進による慢性糸球体疾患の組織修復治療法の開発-腎移植法を用いて-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

骨髄由来細胞による糸球体再構築機序の解明とその臨床応用への試みPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 「腎と透析」ベッドサイド検査事典「遺伝学的検査：ミトコンドリア異常症」2018

Author(s)

Total Pages

Publisher

Data Source

[Book] 医学のあゆみ（特集：ポドサイト障害-腎障害における新たな視点）2018

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] High glucose repatterns human podocyte energy metabolism during differentiation and diabetic nephropathy2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 7501 T>A mitochondrial DNA variant in a patient with glomerulosclerosis2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathological similarities between low birth weight-related nephropathy and nephropathy associated with mitochondrial cytopathy2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hemodialysis patients born with a low birth weight should have a different time course of kidney diseases than those born with a normal birth weight.2013

Author(s)

Journal Title

Data Source

[Journal Article] Podocyte energy metabolism and glomerular diseases.2013

Author(s)

Journal Title

Imasawa Toshiyuki 今澤俊之

今澤俊之イマサワトシユキ

IMASAWA Toshiyuki 今澤俊之

[Presentation] シンポジウム3　腎臓研究の最前線「多層的Omics解析によるCKD研究」2021

[Presentation] シンポジウム6　腎診療におけるビッグデータ：何のために何ができる？「腎疾患における多層的オミックス解析研究の展望」2020

[Presentation] 教育講演5　「糖尿病性腎臓病の rapid decliner の病態を理解する」2020