Onuma Kenji 小沼賢治

Researcher Number	80348557
Other IDs
Affiliation (Current)	2025: 北里大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2014 – 2024: 北里大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery
Keywords	Principal Investigator ミクログロブリン / 手根管症候群 / ５型コラーゲン / マトリックス産生 / 透析 / コラーゲン / 線維化 / 滑膜下結合組織 / 軟骨細胞シート / 広範囲軟骨欠損 … More / 塩基性線維芽細胞増殖因子 / 滑膜幹細胞移植 / 培養軟骨細胞移植 / 滑膜間葉系細胞移植 / 骨軟骨欠損モデル / 間葉系幹細胞 / 骨軟骨欠損 / 滑膜由来間葉系細胞移植 / 同種骨移植 / 広範囲骨軟骨欠損 / 成長因子 / コラーゲン結合蛋白 / 同種骨軟骨組織移植 / 骨軟骨移植 / 同種移植 / 組織保存 / 成長因子固相化 / 成長因子固相化技術 / 同種骨軟骨移植 Less

β2-ミクログロブリンを介した滑膜下結合組織線維化機構の解明と治療シーズの探索Principal Investigator
- Principal Investigator
  
  小沼賢治
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kitasato University
Elucidation of the Mechanism of Carpal Tunnel Syndrome Onset in Dialysis Patients Focusing on the Fibrosis Mechanism of the Subsynovial Connective TissuePrincipal Investigator
- Principal Investigator
  
  Onuma Kenji
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kitasato University
Establishment of widespread osteochondral defect repair method using the growth factor binding chondrocyte cell-sheet / allogeneic bone complexPrincipal Investigator
- Principal Investigator
  
  Onuma Kenji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kitasato University
Establishment of novel osteochondral allografting combined with growth factor- collagen-binding domain fusion technologyPrincipal Investigator
- Principal Investigator
  
  Onuma Kenji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kitasato University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] β2-Microglobulin Elevates COL5A1 mRNA in the Subsynovial Connective Tissue of Patients Receiving Hemodialysis With Carpal Tunnel Syndrome2022
- Author(s)
  Muneshige K, Onuma K, Sukegewa K, Otake Y, Inoue G, Takaso M, Uchida K
- Journal Title
  
  Cureus
  
  Volume: 14
- DOI
  10.7759/cureus.32423
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09487
[Journal Article] Polymicrobial Extensor Tenosynovitis Including Mycobacterium chelonae Caused by a Dog Bite: A Case Report2021
- Author(s)
  Minato S, Sukegawa K, Onuma K, Otake Y, Iida R, Takaso M.
- Journal Title
  
  JBJS Case Connect
  
  Volume: 11 Issue: 1 Pages: e20.00608-e20.00608
- DOI
  10.2106/jbjs.cc.20.00608
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09487
[Journal Article] Displaced isolated coronal shearing fracture of the trapezoid: a case report2021
- Author(s)
  Otake Y, Sukegawa K, Onuma K, Machida S, Iida R, Takaso M
- Journal Title
  
  Case Reports Plast Surg Hand Surg
  
  Volume: 8 Issue: 1 Pages: 50-55
- DOI
  10.1080/23320885.2021.1894941
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09487
[Journal Article] Effects of the Elbow Flexion Angle on the Radial Nerve Location around the Humerus: A Cadaver Study for Safe Installation of a Hinged External Fixator2018
- Author(s)
  Sukegawa Koji、Kuniyoshi Kazuki、Suzuki Takane、Matsuura Yusuke、Onuma Kenji、Kenmoku Tomonori、Takaso Masashi
- Journal Title
  
  The Journal of Hand Surgery (Asian-Pacific Volume)
  
  Volume: 23 Issue: 03 Pages: 388-394
- DOI
  10.1142/s242483551850042x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10983
[Journal Article] Increase and regulation of synovial calcitonin gene-related peptide expression in patient with painful knee osteoarthritis2017
- Author(s)
  Shotaro Takano, Kentaro Uchida, Gen Inoue, Atsushi Minatani, Masayuki Miyagi, Jun Aikawa, Dai Iwase, Kenji Onuma, Manabu Mukai, Masashi Takaso
- Journal Title
  
  Journal of pain reserch
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462277
[Journal Article] Three-dimensional full-scale bone modeling for preoperative simulation of surgery in patients with elbow contractures due to bone deformities2017
- Author(s)
  Nagura Naoshige、Kenmoku Tomonori、Onuma Kenji、Fukushima Kensuke、Fujimaki Hisako、Takahira Naonobu、Takaso Masashi
- Journal Title
  
  Clinical Case Reports
  
  Volume: 5 Issue: 8 Pages: 1401-1406
- DOI
  10.1002/ccr3.1003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10983, KAKENHI-PROJECT-18K16633
[Journal Article] Increase and regulation of synovial calcitonin gene-related peptide expression in patients with painful knee osteoarthritis2017
- Author(s)
  Takano Shotaro、Uchida Kentaro、Inoue Gen、Minatani Atsushi、Miyagi Masayuki、Aikawa Jun、Iwase Dai、Onuma Kenji、Mukai Manabu、Takaso Masashi
- Journal Title
  
  J Pain Res
  
  Volume: 10 Pages: 1099-1104
- DOI
  10.2147/jpr.s135939
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10983
[Journal Article] Activation of calcitonin gene-related peptide signaling through the prostaglandin E2-EP1/EP2/EP4 receptor pathway in synovium of knee osteoarthritis patients.2016
- Author(s)
  Atsushi Minatani, Kentaro Uchida, Gen Inoue, Shotaro Takano, Jun Aikawa, Masayuki Miyagi, Hisako Fujimaki, Dai Iwase, Kenji Onuma, Toshihide Matsumoto, Masashi Takaso
- Journal Title
  
  Journal of orthopaedic surgery and reserch
  
  Volume: - Issue: 1 Pages: 117-117
- DOI
  10.1186/s13018-016-0460-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462277, KAKENHI-PROJECT-15K20016
[Journal Article] Osteochondritis dissecans of the fourth proximal interphalangeal joint in a Japanese drummer2016
- Author(s)
  Ken Takata, Kenji Onuma, Koji Sukegawa, Masashi Takaso
- Journal Title
  
  Case Reports Plast Surg Hand Surg
  
  Volume: 24 Issue: 1 Pages: 83-85
- DOI
  10.1080/23320885.2016.1257355
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462277
[Journal Article] Hyaluronic Acid (800 kDa) Supplementation of University of Wisconsin Solution Improves Viability of Osteochondral Grafts and Reduces Matrix Metalloproteinase Expression during Cold Preservation.2015
- Author(s)
  Yamada T, Uchida K, Onuma K, Inoue G, Aikawa J, Takano S, Sekiguchi H, Fujimaki H, Miyagi M, Takaso M.
- Journal Title
  
  ScientificWorldJournal
  
  Volume: － Issue: 1
- DOI
  10.1155/2015/631369
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462277
[Journal Article] Hydrogen supplementation of preservation solution improves viability of osteochondral grafts.2014
- Author(s)
  Yamada T, Uchida K, Onuma K, Kuzuno J, Ujihira M, Inoue G, Sato B, Kurokawa R, Sakai R, Takaso M.
- Journal Title
  
  ScientificWorldJournal
  
  Volume: － Pages: 1-7
- DOI
  10.1155/2014/109876
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462277
[Presentation] 手根管症候群患者の滑膜下結合組織におけるHIF-1α発現と線維化関連因子との関連性の検討2020
- Author(s)
  横関雄司、内田健太郎、中脇充章、小沼賢治、助川浩士、見目智紀、大貫裕子、井上玄、高相晶士
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-20K09487
[Presentation] 同種骨移植と滑膜間葉系細胞移植を併用した骨軟骨欠損再生法の有用性の検討2019
- Author(s)
  小沼賢治
- Organizer
  第18回日本組織移植学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10983
[Presentation] 慢性疼痛発症のメカニズムと治療腱板断裂における夜間痛と疼痛関連物質の関連性2017
- Author(s)
  名倉直重, 見目智紀, 内田健太郎, 藤巻寿子, 中脇充章, 大貫裕子, 宮城正行, 井上玄, 助川浩士, 小沼賢治, 高相晶士
- Organizer
  日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17K10983
[Presentation] 手根管症候群の滑膜下結合組織においてtransforming growth factor-βはcyclooxygenase-2とnerve growth factorの発現を制御する2017
- Author(s)
  中脇充章, 内田健太郎, 小沼賢治, 助川浩士, 見目智紀, 名倉直重, 田澤諒, 高野昇太郎, 関口裕之, 相川淳, 大貫裕子, 井上玄, 高相晶士
- Organizer
  日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17K10983
[Presentation] Hydrogen Prolongs Cold Preservation of Osteochondral Allografts
- Author(s)
  Kenji Onuma, Kentaro Uchida, Takuya Yamada, Gen Inoue, Kouji Naruse, Ken Urabe, Moritoshi Itoman, Masashi Takaso
- Organizer
  The 15th International conference of Asia-Pacific Association of Surgical Tissue Banking
- Place of Presentation
  長良川国際会議場（岐阜県岐阜市）
- Year and Date
  2014-08-27 – 2014-08-29
- Data Source
  KAKENHI-PROJECT-26462277

1. 内田健太郎 (50547578)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
2. 齋藤亘 (60439099)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 占部憲 (90284489)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 助川浩士 (60458809)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. MATSUSHITA Osamu (00209537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 井上玄 (80594209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. 松本俊英 (10623184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 佐藤雅 (40611843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 板倉誠 (30398581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 松井崇 (30463582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 小寺義男 (60265733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 稲橋佑起 (70645522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Onuma Kenji 小沼 賢治

Research Projects

Research Products

Co-Researchers

β2-ミクログロブリンを介した滑膜下結合組織線維化機構の解明と治療シーズの探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the Mechanism of Carpal Tunnel Syndrome Onset in Dialysis Patients Focusing on the Fibrosis Mechanism of the Subsynovial Connective TissuePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of widespread osteochondral defect repair method using the growth factor binding chondrocyte cell-sheet / allogeneic bone complexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of novel osteochondral allografting combined with growth factor- collagen-binding domain fusion technologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] β2-Microglobulin Elevates COL5A1 mRNA in the Subsynovial Connective Tissue of Patients Receiving Hemodialysis With Carpal Tunnel Syndrome2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Polymicrobial Extensor Tenosynovitis Including Mycobacterium chelonae Caused by a Dog Bite: A Case Report2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Displaced isolated coronal shearing fracture of the trapezoid: a case report2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of the Elbow Flexion Angle on the Radial Nerve Location around the Humerus: A Cadaver Study for Safe Installation of a Hinged External Fixator2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increase and regulation of synovial calcitonin gene-related peptide expression in patient with painful knee osteoarthritis2017

Author(s)

Journal Title

Data Source

[Journal Article] Three-dimensional full-scale bone modeling for preoperative simulation of surgery in patients with elbow contractures due to bone deformities2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increase and regulation of synovial calcitonin gene-related peptide expression in patients with painful knee osteoarthritis2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of calcitonin gene-related peptide signaling through the prostaglandin E2-EP1/EP2/EP4 receptor pathway in synovium of knee osteoarthritis patients.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Osteochondritis dissecans of the fourth proximal interphalangeal joint in a Japanese drummer2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hyaluronic Acid (800 kDa) Supplementation of University of Wisconsin Solution Improves Viability of Osteochondral Grafts and Reduces Matrix Metalloproteinase Expression during Cold Preservation.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hydrogen supplementation of preservation solution improves viability of osteochondral grafts.2014

Author(s)

Journal Title

Onuma Kenji 小沼賢治

[Presentation] 慢性疼痛発症のメカニズムと治療腱板断裂における夜間痛と疼痛関連物質の関連性2017