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Takaki Akinobu  高木 章乃夫

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… Alternative Names

高木 章乃夫  タカキ アキノブ

TAKAKI Akinobu  高木 章乃夫

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Researcher Number 80359885
External Links
Affiliation (Current) 2025: 岡山大学, 医歯薬学域, 教授
Affiliation (based on the past Project Information) *help 2022 – 2023: 岡山大学, 医歯薬学域, 教授
2016 – 2022: 岡山大学, 医歯薬学総合研究科, 准教授
2021: 岡山大学, 医歯薬学域, 准教授
2014 – 2015: 岡山大学, 医歯(薬)学総合研究科, 准教授
2012: 岡山大学, 医歯(薬)学総合研究科, 准教授 … More
2012: 岡山大学, 大学院・医歯薬学総合研究科, 准教授
2010 – 2011: 岡山大学, 大学院・医歯薬学総合研究科, 講師
2003 – 2006: 岡山大学, 医学部・歯学部附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Gastroenterology
Except Principal Investigator
Gastroenterology / Basic Section 58060:Clinical nursing-related / Medium-sized Section 57:Oral science and related fields / Otorhinolaryngology
Keywords
Principal Investigator
肝細胞癌 / 内科 / 細菌 / 腸内細菌叢解析 / 腸内環境 / 腸内細菌叢 / 膵癌 / Proteome analysis / Hepatocellular carcinoma / プロテオーム解析 … More / 脂肪肝 / 胆管細胞癌 / 抗酸化薬 / 酸化ストレス / 胆管癌 / 非アルコール性脂肪性肝炎 / 肝癌 / マイクロキメリズム解析 / 免疫応答 / 肝移植 / 制御性T細胞 / C型肝炎 / 肝臓移植 … More
Except Principal Investigator
健康行動 / 断酒 / 看護 / アルコール性肝障害 / HLA / 肝細胞癌 / Gamification / メタボリックシンドローム / メタゲノム解析 / モデルマウス / 非アルコール性脂肪肝炎 / コラーゲン結合タンパク / 口腔細菌叢 / Streptococcus mutans / 看護支援 / 脳死肝移植 / 生体肝移植 / 肝移植 / 内視鏡治療 / 細胞シート / 内視鏡 / 経口的治療 / 咽頭癌 / 再生医療 / tumor marker / angiogenesis / liver regeneration / 腫瘍マーカー / 血管新生 / 肝再生 / hepatocellular carcinoma / signal transduction / Caspase / Interferon / マイクロアレイ / 5-FU / アポトーシス / 情報伝達経路 / カスパーゼ / インターフェロン / dendritic cell / immune response / hepatitis C virus / プロテアゾーム / HCV / C型肝炎 / 抗原特異的刺激 / 樹状細胞 / 免疫応答 / C型肝炎ウイルス / 発癌 / C型慢性肝炎 / B型肝炎ウイルス Less
  • Research Projects

    (12 results)
  • Research Products

    (66 results)
  • Co-Researchers

    (30 People)
  •  アルコール性肝障害患者の断酒への「態度・信念の変容」解明とGamification tool開発

    • Principal Investigator
      山田 隆子
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58060:Clinical nursing-related
    • Research Institution
      Himeji Dokkyo University
  •  Oral microbiome analysis for elucidation of non-alcoholic steatohepatitis mechanism and development of preventive strategy

    • Principal Investigator
      Nakano Michiyo
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Okayama University
  •  Alcoholic liver disease patients who have undergone brain death or living donor liver transplantation Health Behaviors of Alcoholic Liver Injured Patients

    • Principal Investigator
      Yamada Takako
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58060:Clinical nursing-related
    • Research Institution
      Himeji Dokkyo University
      Prefectural University of Hiroshima
  •  Investigating intestinal environments as risks for pancreatico-biliary cancersPrincipal Investigator

    • Principal Investigator
      Takaki Akinobu
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Okayama University
  •  Regenerative medicine therapy by squamous cell sheet transplantation for artificial ulcer by endoscopic assisted surgery for pharyngeal cancer

    • Principal Investigator
      Keisuke Hori
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tokyo Women's Medical University
  •  Development of treatment protocol for oxidative stress in non-alcoholic steatohepatitis and liver cancerPrincipal Investigator

    • Principal Investigator
      Takaki Akinobu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Okayama University
  •  To develop a new immune therapy for post liver transplantation hepatitis C.Principal Investigator

    • Principal Investigator
      TAKAKI Akinobu
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Okayama University
  •  Proteomic analysis of liver cells infected with hepatitis C virusPrincipal Investigator

    • Principal Investigator
      TAKAKI Akinobu
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Okayama University
  •  C型慢性肝炎患者におけるB型肝炎ウイルス遺伝子の存在と発癌の関連

    • Principal Investigator
      藤岡 真一
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Okayama University
  •  Liver regeneration was affected by carboxylase gene transfer.

    • Principal Investigator
      SHIRAHA Hidenori, 白鳥 康史
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Okayama University
  •  Molecular mechanisms of chronic hepatitis C progression

    • Principal Investigator
      IWASAKI Yoshiaki
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Okayama University
  •  Analysis of interferon related gene regulation as a proapoptotic function against hepatocellular carcinoma

    • Principal Investigator
      SAKAGUCHI Kohsaku
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Okayama University

All 2020 2017 2016 2015 2012 2010 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] Liver pathophysiology ;Therapies & Antioxidants.2017

    • Author(s)
      Takaki A, Uchida D, Yamamoto K.
    • Total Pages
      881
    • Publisher
      Elsevier Academic Press.
    • Data Source
      KAKENHI-PROJECT-26461006
  • [Book] Advances in Medicine and Biology.2016

    • Author(s)
      Adachi T, Takaki A, Okada H.
    • Total Pages
      236
    • Publisher
      Nova Biomedicals
    • Data Source
      KAKENHI-PROJECT-26461006
  • [Journal Article] Early Chimerism After Liver Transplantation Reflects the Clinical Course of Recurrent Hepatitis C.2017

    • Author(s)
      Utsumi M, Takaki A, Umeda Y, Koike K, Napier SC, Watanabe N, Shinoura S, Yoshida R, Nobuoka D, Yasunaka T, Oto T, Araki M, Yamamoto K, Fujiwara T, Yagi T.
    • Journal Title

      Ann Transplant.

      Volume: 22 Pages: 156-165

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461006
  • [Journal Article] Oxidative stress controlling agents are effective for small intestinal injuries induced by non-steroidal anti-inflammatory drugs.2017

    • Author(s)
      Kono Y, Kawano S, Takaki A, Shimomura Y, Onji M, Ishikawa H, Takahashi S, Horii J, Kobayashi S, Kawai D, Yamamoto K, Okada H.
    • Journal Title

      J Gastroenterol Hepatol.

      Volume: 32 Issue: 1 Pages: 136-145

    • DOI

      10.1111/jgh.13424

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461006
  • [Journal Article] Serum-inducible protein (IP)-10 is a disease progression-related marker for non-alcoholic fatty liver disease.2017

    • Author(s)
      Wada N, Takaki A, Ikeda F, Yasunaka T, Onji M, Nouso K, Nakatsuka A, Wada J, Koike K, Miyahara K, Shiraha H, Yamamoto K, Okada H.
    • Journal Title

      Hepatol Int

      Volume: 11 Issue: 1 Pages: 115-124

    • DOI

      10.1007/s12072-016-9773-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25220206, KAKENHI-PROJECT-26293218, KAKENHI-PROJECT-26461006, KAKENHI-PROJECT-17K09861
  • [Journal Article] The Serum Oxidative/Anti-oxidative Stress Balance Becomes Dysregulated in Patients with Non-alcoholic Steatohepatitis Associated with Hepatocellular Carcinoma2017

    • Author(s)
      Shimomura Y, Takaki A, Wada N, Yasunaka T, Ikeda F, Maruyama T, Tamaki N, Uchida D, Onishi H, Kuwaki K, Nakamura S, Nouso K, Miyake Y, Koike K, Tomofuji T, Morita M, Yamamoto K, Okada H.
    • Journal Title

      Intern. Med.

      Volume: 56 Issue: 3 Pages: 243-251

    • DOI

      10.2169/internalmedicine.56.7002

    • NAID

      130005310286

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25220206, KAKENHI-PROJECT-26461006
  • [Journal Article] Oxidative stress balance is dysregulated and represents an additional target for treating cholangiocarcinoma2016

    • Author(s)
      Daisuke Uchida, Akinobu Takaki, Hisashi Ishikawa, Yasuko Tomono, Kato H, Tsutsumi K, Tamaki N, Maruyama T, Tomofuji T, Tsuzaki R, Yasunaka T, Koike K, Matsushita H, Ikeda F, Shiraha H, Nouso K, Yoshida R, Umeda Y, Shinoura S, Yagi T, Fujiwara T, Morita M, Fukushima M, Yamamoto K, Okada H
    • Journal Title

      Free Radical Research

      Volume: E pub ahead of print Issue: 7 Pages: 732-743

    • DOI

      10.3109/10715762.2016.1172071

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461006
  • [Journal Article] Short-term high-dose followed by long-term low-dose hepatitis B immunoglobulin and lamivudine therapy prevented recurrent hepatitis B after liver transplantation.2007

    • Author(s)
      Takaki A., Yagi T., Iwasaki Y., Sadamori H., Matsukawa H., Matsuda H., Shinoura S., Umeda Y., Miyake Y., Terada R., Kobashi H., Sakaguchi K., Tanaka N., Shiratori Y.
    • Journal Title

      Transplantation. 83

      Pages: 231-233

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Des-gamma-carboxyl prothrombin-promoted vascular endothelial cell proliferation and migration.2007

    • Author(s)
      Fujikawa T, Shiraha H, Takaki A, et al.
    • Journal Title

      Journal of Biological Cemistry 282(12)

      Pages: 8741-8748

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590647
  • [Journal Article] Short-term high-dose followed by long-term low-dose HBIG and lamivudine prevented recurrent hepatitis B after liver transplantation.2007

    • Author(s)
      Takaki A, Yagi T, et al.
    • Journal Title

      Transplantation 83(2)

      Pages: 231-3

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590647
  • [Journal Article] A homosexual Japanese man with acute hepatitis due to hepatitis B virus genotype ae, concurrent with amebic colitis.2007

    • Author(s)
      hepatitis C virus infection may improve patient survival.Miyake, Y., Iwasaki, Y., Ishikawa, S., Tatsukawa, M., Nawa, T., Kato, J., Takaki, A., Kobashi, H., Sakaguchi, K., Shiratori, Y.
    • Journal Title

      Acta Med Okayama. 61

      Pages: 35-39

    • NAID

      120002311633

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Short-term high-dose followed by long-term low-dose HBIG and lamivudinepreventedrecurrenthepatitisBafter liver transplantation.2007

    • Author(s)
      Takaki A, Yagi T, et al.
    • Journal Title

      Transplantation 83 (2)

      Pages: 231-233

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590647
  • [Journal Article] Contrast-enhanced ultrasonography depicts small tumor vessels for the evaluation of pancreatic tumors.2007

    • Author(s)
      Okamoto Y., Kawamoto H., Takaki A., Ishida E., Ogawa T., Kuwaki K., Kobayashi Y., Sakaguchi K., Shiratori Y.
    • Journal Title

      Eur J Radiol. 61

      Pages: 163-169

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Des-gamma-carboxyl prothrombin-promoted vascular endothelial cell proliferation and migration.2007

    • Author(s)
      Fujikawa T, Shiraha H, Takaki A, et al.
    • Journal Title

      Journal of Biological Chemistry 282(12)

      Pages: 8741-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590647
  • [Journal Article] Des-gamma-carboxy prothrombin-promoted vascular endothelial cell proliferation and migration.2007

    • Author(s)
      Fujikawa T, Shiraha H, Ueda N, Takaoka N, Nakanishi Y, Matsuo N, Tanaka S, Nishina SI, Suzuki M, Takaki A, Sakaguchi K, Shiratori Y.
    • Journal Title

      J Biol Chem. (In press)

    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Short-term high-dose followed by long-term low-dose hepatitis B immunoglobulin and lamivudine therapy prevented recurrent hepatitis B after liver transplantation.2007

    • Author(s)
      Takaki A, Yagi T, Iwasaki Y, Sadamori H, Matsukawa H, Matsuda H, Shinoura S, Umeda Y, Miyake Y, Terada R, Kobashi H, Sakaguchi K, Tanaka N, Shiratori Y.
    • Journal Title

      Transplantation. 83・2

      Pages: 231-3

    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Short-term high-dose followed by long-term low-dose hepatitis B immunoglobulin and lamivudine therapy prevented recurrent hepatitis B after liver transplantation.2007

    • Author(s)
      Takaki A, Yagi T, Iwasaki Y, Sadamori H, Matsukawa H, Matsuda H, Shinoura S, Umeda Y, Miyake Y, Terada R, Kobashi H, Sakaguchi K, Tanaka N, Shiratori Y
    • Journal Title

      Transplantation. 83・2

      Pages: 231-233

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Des-gamma -carboxy prothrombin-promoted vascular endothelial cell proliferation and migration.2007

    • Author(s)
      Fujikawa T, Shiraha H, Ueda N, Takaoka N, Nakanishi Y, Matsuo N, Tanaka S, Nishina SI, Suzuki M, Takaki A, Sakaguchi K, Shiratori Y
    • Journal Title

      J Biol Chem. 282・12

      Pages: 8741-8748

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] A homosexual Japanese man with acute hepatitis due to hepatitis B virus genotype ae, concurrent with amebic colitis.2007

    • Author(s)
      Miyake Y, Iwasaki Y, Ishikawa S, Tatsukawa M, Nawa T, Kato J, Takaki A, Kobashi H, Sakaguchi K, Shiratori Y
    • Journal Title

      Acta Med Okayama. 61・1

      Pages: 35-39

    • NAID

      120002311633

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] A homosexual Japanese man with acute hepatitis due to hepatitis B virus genotype ae, concurrent with amebic colitis.2007

    • Author(s)
      Miyake Y, Iwasaki Y, Ishikawa S, Tatsukawa M, Nawa T, Kato J, Takaki A, Kobayashi H, Sakaguchi K, Shiratori Y.
    • Journal Title

      Acta Med Okayama. 61・1

      Pages: 35-9

    • NAID

      120002311633

    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Contrast-enhanced ultrasonography depicts small tumor vessels for the evaluation of pancreatic tumors.2007

    • Author(s)
      Okamoto Y, Kawamoto H, Takaki A, et al.
    • Journal Title

      European Journal of Radiology 61(1)

      Pages: 163-169

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590647
  • [Journal Article] Des-gamma-carboxyl prothrombin-promoted vascular endothelial cell proliferation and migration.2007

    • Author(s)
      Fujikawa T., Shiraha H., Ueda N., Takaoka N., Nakanishi Y., Matsuo N., Tanaka S., Nishina S., Suzuki M., Takaki A., Sakaguchi K.Shiratori Y.
    • Journal Title

      J Biol Chem 282

      Pages: 8741-8748

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Endoscopic therapy for bleeding esophageal varices improves the outcome of Child C cirrhotic patients.2006

    • Author(s)
      Hori S, Takaki A, et al.
    • Journal Title

      Journal of Gastroenterology and Hepatology 21(11)

      Pages: 1704-1709

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590647
  • [Journal Article] Contrast-enhanced ultrasonography depicts small tumor vessels for the evaluation of pancreatic tumors.2006

    • Author(s)
      Okamoto Y, Kawamoto H, Takaki A, Ishida E, Ogawa T, Kuwaki K, Kobayashi Y, Sakaguchi K, Shiratori Y.
    • Journal Title

      Eur J Radiol. 61・1

      Pages: 163-9

    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Combination of 5-FU and IFNalpha enhances IFN signaling pathway and caspase-8 activity, resulting in marked apoptosis in hepatoma cell lines.2006

    • Author(s)
      Koike K., Takaki A., Tatsukawa M., Suzuki M., Shiraha H., Iwasaki Y., Sakaguchi K., Shiratori Y.
    • Journal Title

      Int J Oncol 29

      Pages: 1253-1261

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Early detection and quantification of lamivudine-resistant hepatitis B virus mutants by fluorescent biprobe hybridization assay in lamivudine-treated patients.2006

    • Author(s)
      Umeoka F., Iwasaki Y., Matsumura M., Takaki A., Kobashi H., Tatsukawa M., Shiraha H., Fujioka S., Sakaguchi K., Shiratori Y.
    • Journal Title

      J Gastroenterol. 41

      Pages: 693-701

    • NAID

      10019282411

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Contrast-enhanced ultrasonography depicts small tumor vessels for the evaluation of pancreatic tumors.2006

    • Author(s)
      Okamoto Y, Kawamoto H, Takaki A, Ishida E, Ogawa T, Kuwaki K, Kobayashi Y, Sakaguchi K, Shiratori Y
    • Journal Title

      Eur J Radiol. 61・1

      Pages: 163-169

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Combination of 5-FU IFNalpha enhances IFN signaling pathway and caspase-8 activity, resulting in marked apoptosis in hepatoma cell lines.2006

    • Author(s)
      Koike K, Takaki A, et al.
    • Journal Title

      International Journal of Oncology 29 (5)

      Pages: 1253-61

    • Data Source
      KAKENHI-PROJECT-17590647
  • [Journal Article] Long-term monitoring of platelet count, as a non-invasive marker of hepatic fibrosis progression and/or regression in patients with chronic hepatitis Cafter interferon therapy.2006

    • Author(s)
      Taniguchi H, Iwasaki Y, Takaki A, Shiratori Y, et a;.
    • Journal Title

      J Gastroenterol Hepatol 21

      Pages: 281-287

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590649
  • [Journal Article] Early detection and quantification of lamivudine-resistant hepatitis B virus mutants by fluorescent biprobe hybridization assay in lamivudine-treated patients.2006

    • Author(s)
      Umeoka F, Iwasaki Y, Matsumura M, Takaki A, Kobashi H, Tatsukawa M, Shiraha H, Fujioka S, Sakaguchi K, Shiratori Y
    • Journal Title

      J Gastroenterol. 41・7

      Pages: 693-701

    • NAID

      10019282411

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Combination of 5=FU and IFNalpha enhances IFN signaling pathway and caspase-8 activity, resulting in marked apoptosis in hepatoma cell lines.2006

    • Author(s)
      Koike K, Takaki A, et al.
    • Journal Title

      International Journal of Oncology 29(5)

      Pages: 1253-61

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590647
  • [Journal Article] Long-term monitoring of platelet count, as a non-invasive marker of hepatic fibrosis progression and/or regression in patients with chronic hepatitis C after interferon therapy.2006

    • Author(s)
      Taniguchi H, Iwasaki Y, Takaki A, Shiratori Y, et al.
    • Journal Title

      J Gastroenterol Hepatol 21

      Pages: 281-287

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590649
  • [Journal Article] Combination of 5-FU and IFNalpha enhances IFN signaling pathway and caspase-8 activity, resulting in marked apoptosis in hepatoma cell lines.2006

    • Author(s)
      Koike K, Takaki A, Tatsukawa M, Suzuki M, Shiraha H, Iwasaki Y, Sakaguchi K, Shiratori Y
    • Journal Title

      Int J Oncol. 29・5

      Pages: 1253-1261

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Combination of 5-FU and IFNalpha enhances IFN signaling pathway and caspase-8 activity, resulting in marked apoptosis in hepatoma cell lines.2006

    • Author(s)
      Koike K, Takaki A, et al.
    • Journal Title

      International Journal of Oncology 29 (5)

      Pages: 1253-1261

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590647
  • [Journal Article] Early detection and quantification of lamivudine-resistant hepatitis B virus mutants by fluorescent biprobe hybridization assay in lamivudine-treated patients.2006

    • Author(s)
      Umeoka F, Iwasaki Y, Takaki A, et al.
    • Journal Title

      Journal of Gastroenterology 41(7)

      Pages: 693-701

    • NAID

      10019282411

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590647
  • [Journal Article] Combination of 5-FU and IFNalpha enhances IFN signaling pathway and caspase-8 activity, resulting in marked apoptosis in hepatoma cell lines.2006

    • Author(s)
      Koike K, Takaki A, Tatsukawa M, Suzuki M, Shiraha H, IWasaki Y, Sakaguchi K, Shiratori Y.
    • Journal Title

      Int J Oncol. 29・5

      Pages: 1253-61

    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Early detection and quantification of lamivudine-resistant hepatitis B virus mutants by fluorescent biprobe hybridization assay in lamivudine-treated patients.2006

    • Author(s)
      Umeoka F, Iwasaki Y, Matsumura M, Takaki A, Kobashi H, Tatsukawa M, Shiraha H, Fujioka S, Sakaguchi K, Shiratori Y.
    • Journal Title

      J Gastroenterol. 41・7

      Pages: 693-701

    • NAID

      10019282411

    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] 肝臓 1.C型肝炎:ウイルス、病態、診断2005

    • Author(s)
      高木章乃夫, 白鳥康史
    • Journal Title

      Annual Review 消化器 2005

      Pages: 259-262

    • Data Source
      KAKENHI-PROJECT-15590649
  • [Journal Article] Des-gamma-carboxy prothrombin is a potential autologous growth factor for hepatocellular carcinoma.2005

    • Author(s)
      Suzuki M., Shiraha H., Fujikawa T., Takaoka N., Ueda N.Nakanishi Y., Koike K., Takaki A.Shiratori Y.
    • Journal Title

      J Biol Chem 280

      Pages: 6409-6415

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] C型肝炎ウイルス(HCV)構成遺伝子導入及びHCVタンパク貪食による樹状細胞機能の変化2005

    • Author(s)
      高木章乃夫, 岩崎良章, 白鳥康史
    • Journal Title

      肝臓 46Suppl.2

    • Data Source
      KAKENHI-PROJECT-15590649
  • [Journal Article] Des-{gamma}-carboxy Prothrombin Is a Potential Autologous Growth Factor for Hepatocellular Carcinoma2005

    • Author(s)
      Suzuki, M.Shiraha, H, Takaki, A., Shiratori Y.et al.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 6409-6415

    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] Des-{gamma}-carboxy Prothrombin Is a Potential Autologous Growth Factor for Hepatocellular Carcinoma2005

    • Author(s)
      Suzuki, M., Shiraha, H, Takaki, A., Shiratori Y.et al.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 6409-6415

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390210
  • [Journal Article] 5-FU and IFN alpha8 combination treatment induce more severe apoptosis and caspase activities than 5-FU and IFN alpha2 treatment in hepatoma cell lines2004

    • Author(s)
      Koike K., Takaki A., Sakaguchi K., et al.
    • Journal Title

      Digestive Disease Week

      Pages: 813-813

    • Data Source
      KAKENHI-PROJECT-15590650
  • [Journal Article] Hepatitis C viral protein genes lower the expression of CD86 on dendritic cells of healthy donors and may hamper the proliferative T cell response2004

    • Author(s)
      Takaki A., Iwasaki Y., et al.
    • Journal Title

      11^<th> International symposium on hepatitis C virus and related viruses 11

      Pages: 192-192

    • Data Source
      KAKENHI-PROJECT-15590649
  • [Journal Article] C型肝炎ウイルス構成遺伝子導入による樹状細胞表面マーカー及び機能の検討2004

    • Author(s)
      高木章乃夫, 岩崎良章 他
    • Journal Title

      肝臓 45(1)

    • Data Source
      KAKENHI-PROJECT-15590649
  • [Journal Article] インターフェロンα8はα2よりもcaspaseを強く活性化し、抗癌剤による肝細胞癌株アポトーシスを誘導する2004

    • Author(s)
      小池和子, 高木章乃夫, 坂口孝作 他
    • Journal Title

      肝臓 45(2)

    • Data Source
      KAKENHI-PROJECT-15590650
  • [Journal Article] 岡山大学病院において 特集ウイルス肝炎と肝移植III.施設における現状と対策 : 内科医より2004

    • Author(s)
      高木章乃夫, 坂口孝作他
    • Journal Title

      今日の移植 18

      Pages: 213-215

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590650
  • [Journal Article] 5-FUによる肝癌細胞株アポトーシス誘導に対するインターフェロンα2とα8の増強効果の違いはcaspase活性化と関係する2004

    • Author(s)
      小池和子, 高木章乃夫, 坂口孝作 他
    • Journal Title

      肝臓 45(1)

    • Data Source
      KAKENHI-PROJECT-15590650
  • [Presentation] アルコール性肝障害(ALD:alcoholic liver disease)により生体肝移植を受けた患者が断酒を継続するプロセス2020

    • Author(s)
      山田隆子,高木章乃夫,八木孝仁,鶴園真理,有森千聖,岡田裕之
    • Organizer
      第56回日本移植学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K10879
  • [Presentation] アルコール性肝障害により脳死肝移植を受けた患者が断酒を継続できるまでのプロセス-1例の語りを分析して-2020

    • Author(s)
      山田隆子,高木章乃夫,八木孝仁,鶴園真理,有森千聖,岡田裕之
    • Organizer
      第38回日本肝臓移植学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K10879
  • [Presentation] アルコール性肝障害により脳死肝移植を受けた患者が断酒を継続できるまでのプロセス-1例の語りを分析して-2020

    • Author(s)
      山田隆子,高木章乃夫,八木孝仁,鶴園真理,有森千聖,岡田裕之
    • Organizer
      第38回日本肝移植学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K10879
  • [Presentation] インスリン抵抗性とTLR2刺激の非アルコール性脂肪性肝炎病態への関与2016

    • Author(s)
      和田望,高木章乃夫,岡田裕之
    • Organizer
      第102回日本消化器病学会総会
    • Place of Presentation
      東京
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-26461006
  • [Presentation] NSAIDs長期内服者における酸化ストレス状態とカプセル内視鏡所見についての検討2016

    • Author(s)
      河野吉泰,高木章乃夫,川野誠司
    • Organizer
      第91回日本消化器内視鏡学会総会
    • Place of Presentation
      東京
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-26461006
  • [Presentation] インスリン抵抗性と腸内細菌の非アルコール性脂肪性肝炎への関与についての検討2016

    • Author(s)
      和田望,高木章乃夫,岡田裕之
    • Organizer
      第53回日本消化器免疫学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2016-07-14
    • Data Source
      KAKENHI-PROJECT-26461006
  • [Presentation] Oxidative Stress Controlling Agents Are Effective for NSAIDs-Induced Small Intestinal Injuries2016

    • Author(s)
      Kono Y, Takaki A, Kawano S, Okada H.
    • Organizer
      Digestive Disease Week 2016
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-05-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461006
  • [Presentation] Serum IP-10 is a highly sensitive marker for discriminating non-alcoholic fatty liver and non-alcoholic steatohepatitis2016

    • Author(s)
      Wada N, Takaki A, Okada H.
    • Organizer
      Digestive Disease Week 2016
    • Place of Presentation
      San Diego、USA
    • Year and Date
      2016-05-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461006
  • [Presentation] Oxidative stress balance is dysregulated in cholangiocarcinoma that could be improved with L-carnitine administration2015

    • Author(s)
      Uchida D, Takaki A, Tomono Y, Fukushima M, Yamamoto K.
    • Organizer
      Digestive Disease Week 2015,
    • Place of Presentation
      Washington DC
    • Year and Date
      2015-05-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461006
  • [Presentation] 胆管癌における酸化ストレスと便中胆汁酸の関連性の検討2015

    • Author(s)
      内田大輔、高木章乃夫、友野靖子
    • Organizer
      第19回日本肝臓学会大会
    • Place of Presentation
      東京
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26461006
  • [Presentation] 胆管癌における酸化ストレスの関与と糖尿病関連肝内胆管細胞癌モデルにおける抗酸化治療の有用性2015

    • Author(s)
      内田大輔、高木章乃夫、友野靖子
    • Organizer
      第51回日本肝臓学会総会
    • Place of Presentation
      熊本
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26461006
  • [Presentation] Sequential changes of regulatory T cell fraction after liver transplantation2012

    • Author(s)
      Takaki A, Koike K, Yagi T, Sadamori H, Shinoura S, Umeda Y, Yoshida R, Sato D, Utsumi M, Yasunaka T, Fujiwara T, Yamamoto K
    • Organizer
      AASLD2012
    • Place of Presentation
      Boston, USA
    • Data Source
      KAKENHI-PROJECT-22590735
  • [Presentation] Low frequency of Tr1 in peripheral blood correlated with persistent normal ALT in chronic hepatitis C after liver transplantation2012

    • Author(s)
      小池和子(高木章乃夫)
    • Organizer
      United European Gastroenterology Week.2012.
    • Place of Presentation
      Amsterdam,Holland
    • Data Source
      KAKENHI-PROJECT-22590735
  • [Presentation] Sequential changes of regulatory T cell fraction after liver transplantation.2012

    • Author(s)
      高木章乃夫
    • Organizer
      American Association for the Society of Liver Disease.2012.
    • Place of Presentation
      Boston,USA
    • Data Source
      KAKENHI-PROJECT-22590735
  • [Presentation] Low frequency of Tr1 in peripheral blood correlated with persistent normal ALT in chronic hepatitis C after liver transplantation2012

    • Author(s)
      Koike K, Takaki A, Yagi T, Sadamori H, Shinoura S, Umeda Y, Yoshida R, Sato D, Utsumi M, Yasunaka T, Yamamoto K
    • Organizer
      UEGW2012
    • Place of Presentation
      Amsterdam, Holland
    • Data Source
      KAKENHI-PROJECT-22590735
  • [Presentation] C型肝炎ウイルス蛋白による樹状細胞機能変化の検討2010

    • Author(s)
      高木章乃夫,小池和子,山本和秀
    • Organizer
      第96回日本消化器病学会総会
    • Place of Presentation
      新潟
    • Year and Date
      2010-04-22
    • Data Source
      KAKENHI-PROJECT-22590735
  • [Presentation] Costimulatory molecule PD-L2 is expressed in the hepatocytes of patients with recurrent hepatitis C after liver transplantation2010

    • Author(s)
      Takaki A, Koike K, Yagi T, Iwasaki Y, Sadamori H, Matsuda H, Yasunaka T, Miyake Y, Ikeda F, Kobashi H, Kazuhide Yamamoto
    • Organizer
      HCV2010
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-22590735
  • [Presentation] 糖尿病関連肝内胆管細胞癌モデルにおける抗酸化治療の有用性と腸内細菌叢の変化の検討

    • Author(s)
      内田大輔、高木章乃夫、他
    • Organizer
      第101回日本消化器病学会総会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2015-04-23 – 2015-04-25
    • Data Source
      KAKENHI-PROJECT-26461006
  • 1.  SHIRAHA Hidenori (40379748)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 12 results
  • 2.  IWASAKI Yoshiaki (00314667)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 3.  SHIRATORI Yasushi (70196624)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 25 results
  • 4.  YAGI Takahito (00304353)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 5.  WATANABE Nobukazu (10334278)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  SAKAGUCHI Kohsaku (90235143)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 22 results
  • 7.  KATO Jun (90379743)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 8.  Yamada Takako (60382363)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 9.  Keisuke Hori (30749651)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KANAI Nobuo (90318056)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Nakano Michiyo (30359848)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  藤岡 真一 (90346437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  真治 紀之 (70314680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  小出 典男 (20142333)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  太田 成男 (00125832)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  恩地 正浩 (20727391)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  松下 浩志 (20786107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  岡田 裕之 (60263563)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  河原 祥朗 (30420483)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  岩室 雅也 (30645403)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  木股 敬裕 (50392345)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  小野田 友男 (20420482)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  森田 英利 (70257294)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  松本 和幸 (40795027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  高原 政宏 (80738427)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  仲 周平 (10589774)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  麻生 浩司 (90779216)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  岡田 ゆみ (70364099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  ABE Makoto
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  NOUSO Kazuhiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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