Yokouchi Masahiro 横内雅博

… Alternative Names

Researcher Number	80359976
Other IDs
Affiliation (based on the past Project Information) *help	2016: 鹿児島大学, 医歯学域医学部・歯学部附属病院, 講師 2015: 鹿児島大学, 医歯学域医学系, 講師 2010 – 2013: 鹿児島大学, 医学部・歯学部附属病院, 講師 2008: 鹿児島大学, 大学院・医歯学総合研究科, 講師 2007 – 2008: 鹿児島大学, 大学院・医歯学総合研究科, 助教 2005 – 2006: Kagoshima Graduate School of Medical and Dental Sciences, Research Associate, 大学院医歯学総合研究科, 助手 2003 – 2005: 鹿児島大学, 大学院・医歯学総合研究科, 助手
Review Section/Research Field	Principal Investigator Orthopaedic surgery Except Principal Investigator Orthopaedic surgery
Keywords	Principal Investigator 骨肉腫 / 骨軟部肉腫 / 化学療法 / 抗癌剤 / 有害事象 / 超音波 / マイクロバブル / ドラッグデリバリーシステム / デリバリーシステム / 軟骨肉腫 … More Except Principal Investigator 骨肉腫 / 急性脊髄損傷 / アポトーシス / エリスロポエチン / 脊髄損傷 / HMGB-1 / c-Cbl / 骨軟部肉腫 / がん幹細胞 / sarcoma-initiating cell / sarcoma-initiating cells / 神経変性 / spinal cord injury / apoptosis / erythropoietin / spinal cord degeneration / HMGB1 / Spinal Cord Injury / Apoptosis / Erythropoietin / 細胞内シグナル伝達 / 蛋白分解系 / ビスホスホネート / 増殖抑制 / 癌 / シグナル伝達 / 抑制因子 / 遺伝子導入 / osteosarcoma / signal transduction / ubiquitin system / bisphosphonate / negative regulation Less

軟骨肉腫診断マーカーと治療標的候補としてのTGF-βとPEG10の機能解析Principal Investigator
- Principal Investigator
  
  横内雅博
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Target gene screening of TGF-b signaling and functional analysis for differentiation-inducing therapy of chondrosarcomaPrincipal Investigator
- Principal Investigator
  
  Yokouchi Masahiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Anti-tumor effect of doxorubicin with bubble liposome and ultrasoundPrincipal Investigator
- Principal Investigator
  
  YOKOUCHI Masahiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Targeting of osteosarcoma and soft tissue sarcoma initiating cells
- Principal Investigator
  
  KOMIYA Setsurou
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Manifestation of HMGB-1 and Preventive Effect of Degeneration on Spinal Cord Following Acute Traumatic Injury.
- Principal Investigator
  
  ARISHIMA Yoshiya
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
The inhibitory effects of ubiuitin system in signal transduction of osteosarcoma
- Principal Investigator
  
  HAYASHI Kyouji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
The role of ubiquitination in signal transduction of OsteosarcomaPrincipal Investigator
- Principal Investigator
  
  YOKOUCHI Masahiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Preventive effect of erythropoietin on spinal cord degeneration following acute traumatic injury
- Principal Investigator
  
  YONE Kazunori
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University

All 2016 2015 2014 2013 2012 2011 2010 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] SnoN suppresses maturation of chondrocytes by mediating signal cross-talk between transforming growth factor-β and bone morphogenetic protein pathways.2012
- Author(s)
  Kawamura I, Maeda S, Imamura K, Setoguchi T, Yokouchi M, Ishidou Y, Komiya S
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 287(34) Pages: 29101-13
- DOI
  10.1074/jbc.m112.349415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591662, KAKENHI-PROJECT-23592221, KAKENHI-PROJECT-23592222
[Journal Article] 分子レベルからみた整形外科疾患(シリーズ IX) Bubble liposome と超音波を併用した drug delivery system の開発2012
- Author(s)
  上野宜功, 園田祥三, 丸山一雄, 坂本泰二, 横内雅博, 小宮節郎
- Journal Title
  
  整形・災害外科
  
  Volume: 55巻 12号 Pages: 1488-1489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591662
[Journal Article] Clinical implications of determination of safe surgical margins by using a combination of CT and 18FDG-positron emission tomography in soft tissue sarcoma2011
- Author(s)
  Yokouchi M, Terahara M, Nagano S, Arishima Y, Zemmyo M, Yoshioka T, Tanimoto A, Komiya S
- Journal Title
  
  BMC Musculoskelet Disord
  
  Volume: 12 Pages: 166-166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591662
[Journal Article] Clinical implications of determination of safe surgical margins by using a combination of CT and 18FDG-positron emission tomography in soft tissue sarcoma.2011
- Author(s)
  Yokouchi M, Terahara M, Nagano S, Arishima Y, Zemmyo M, Yoshioka T, Tanimoto A, Komiya S.
- Journal Title
  
  BMC Musculoskelet Disord
  
  Volume: 12 Pages: 166-166
- DOI
  10.1186/1471-2474-12-166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591662
[Journal Article] Combination of ultrasound and bubble liposome enhance the effect of doxorubicin and inhibit murine osteosarcoma growth2011
- Author(s)
  Ueno Y, Sonoda S, Suzuki R, Yokouchi M, Kawasoe Y, Tachibana K, Maruyama K, Sakamoto T, Komiya S
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 12(4) Pages: 270-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591662
[Journal Article] Gadd45β expression in chondrosarcoma: a pilot study for diagnostic and biological implications in histological grading2010
- Author(s)
  Zenmyo M, Tanimoto A, Sakakima H, Yokouchi M, Nagano S, Yamamoto T, Ishido Y, Komiya S, Ijiri K
- Journal Title
  
  Diagn Pathol
  
  Volume: 5 Pages: 69-69
- DOI
  10.1186/1746-1596-5-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591662
[Journal Article] Gadd45β expression in chondrosarcoma : A pilot study for diagnostic and biological implications in histological grading2010
- Author(s)
  Zenmyo M, Yokouchi M, (他7名、4番目)
- Journal Title
  
  Diagnostic Pathology.
  
  Volume: 69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591662
[Journal Article] 成人発症骨肉腫の治療における化学療法の意義2010
- Author(s)
  永野聡, 横内雅博, (他6名、2番目)
- Journal Title
  
  整形外科と災害外科
  
  Volume: 59 Pages: 242-245
- NAID
  10026059928
- Data Source
  KAKENHI-PROJECT-22591662
[Journal Article] HAS3-related hyaluronan enhances biological activities necessary for metastasis of osteosarcoma cells2006
- Author(s)
  Tofuku K, Yokouchi M, Murayama T, Minami S, Komiya S
- Journal Title
  
  Int J Oncol. 29(1)
  
  Pages: 175-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] Comparative analysis of gene expression profiles in intact and damaged regions of human osteoarthritic cartilage2006
- Author(s)
  Sato T, Konomi K, Yamasaki S, Aratani S, Tsuchimochi K, Yokouchi M, Masuko-Hongo K, Yagishita N, Nakamura H, Komiya S, Beppu M, Aoki H, Nishioka K, Nakajima T
- Journal Title
  
  Arthritis Rheum. 54(3)
  
  Pages: 808-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] HAS3-related hyaluronan enhances biological activities necessary for metastasis of osteosarcoma cells.2006
- Author(s)
  Tofuku K, Yokouchi M et al.
- Journal Title
  
  International journal of oncology 29 (1)
  
  Pages: 175-183
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591501
[Journal Article] HAS3-related hyaluronan enhances biological activities necessary for metastasis of osteosarcoma cells.2006
- Author(s)
  Tofuku K, Yokouchi M, Murayama T, Minami S, Komiya S.
- Journal Title
  
  International journal of oncology 29(1)
  
  Pages: 175-183
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591501
[Journal Article] 骨肉腫の浸潤・転移において重要な役割をはたすヒアルロン酸の検討2005
- Author(s)
  東福勝宏, 横内雅博, 村山隆, 南周作, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 79巻8号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591501
[Journal Article] 骨肉腫の浸潤・転移において重要な役割をはたすヒアルロン酸の検討2005
- Author(s)
  東福勝宏, 横内雅博, 村山隆, 南周作, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 79・8号
- Data Source
  KAKENHI-PROJECT-16591500
[Journal Article] 骨肉腫のシグナル伝達におけるSrcの役割2004
- Author(s)
  山下芳隆, 横内雅博, 村山隆, 南周作, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 78巻8号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591500
[Journal Article] 骨肉腫細胞株におけるヒアルロン酸の検討2004
- Author(s)
  東福勝宏, 村山隆, 南周作, 横内雅博, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 78巻6号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591501
[Journal Article] 骨肉腫細胞株におけるPDGF受容体の発現とそのシグナル抑制機構2004
- Author(s)
  村山隆, 山下芳隆, 南周作, 横内雅博, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 78・6号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591500
[Journal Article] 小児骨肉腫における有効な分子標的治療の検討2004
- Author(s)
  横内雅博, 村山隆, 山下芳隆, 南周作, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  小児がん 41巻3号
  
  Pages: 675-675
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591500
[Journal Article] 骨肉腫細胞株における窒素含有ビスフォスフォネート剤リセドロネートによる増殖抑制効果の検討2004
- Author(s)
  村山隆, 横内雅博, 山下芳隆, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 78・6号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591500
[Journal Article] 骨肉腫におけるEGFR/Src/Cb1間シグナル伝達機構2004
- Author(s)
  山下芳隆, 横内雅博, 村山隆, 南周作, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 78巻6号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591500
[Journal Article] 腫瘍領域における先端医療の成果と展望 Cb1の増殖因子シグナル制御による骨肉腫治療の可能性2004
- Author(s)
  横内雅博, 村山隆, 山下芳隆, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 78・8号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591500
[Journal Article] 小児骨肉腫における有効な分子標的治療の検討2004
- Author(s)
  横内雅博, 山下芳隆, 村山隆, 南周作, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  日本小児血液学会雑誌 18巻4号
  
  Pages: 414-414
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591501
[Journal Article] 骨肉腫におけるEGFR/Src/Cb1間シグナル伝達機構2004
- Author(s)
  山下芳隆, 横内雅博, 村山隆, 南周作, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 78巻6号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591501
[Journal Article] 小児骨肉腫における有効な分子標的治療の検討2004
- Author(s)
  横内雅博, 山下芳隆, 村山隆, 南周作, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  小児がん 41巻3号
  
  Pages: 675-675
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591501
[Journal Article] The nitrogen-containing bisphosphonate risedronate is a potent inhibitor of osteosarcoma cell growth
- Author(s)
  Takashi Murayama, Masahiro Yokouchi et al.
- Journal Title
  
  (submitted)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591500
[Journal Article] Interaction between EGFR, Src and Cbl in Osteosarcoma
- Author(s)
  Yoshitaka Yamashita, Masahiro Yokouchi et al.
- Journal Title
  
  (submitted)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591500
[Presentation] PEG10はBMP-p38 MAPK経路を介する軟骨肉腫細胞の浸潤を制御する2016
- Author(s)
  篠原直弘, 前田真吾, 松山金寛, 八尋雄平, 今村　勝行, 横内雅博, 永野聡, 石堂康弘, 小宮節郎
- Organizer
  第２９回日本軟骨代謝学会
- Place of Presentation
  広島大学医学部 (広島県　広島市)
- Year and Date
  2016-02-19
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] BMP誘導性のPEG10は軟骨肉腫細胞浸潤能増強を抑制する2015
- Author(s)
  篠原直弘、前田真吾、松山金寛、八尋雄平、横内雅博、石堂康弘、小宮節郎
- Organizer
  第３０回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場 (富山県　富山市)
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] BMP誘導性インプリンティング遺伝子PEG10は軟骨肉腫細胞においてBMPにより活性化されたp38 MAPK経路とMMPs発現抑制を介して浸潤能を制御する2015
- Author(s)
  篠原直弘、前田真吾、松山金寛、八尋雄平、今村勝行、横内雅博、永野聡、石堂康弘、小宮節郎
- Organizer
  第３８回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド(兵庫県　神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] BMP誘導性インプリンティング遺伝子PEG10は p38経路を介して軟骨肉腫細胞の浸潤能を抑制する2015
- Author(s)
  篠原直弘、前田真吾、松山金寛、八尋雄平、横内雅博、石堂康弘、小宮節郎
- Organizer
  第１６回運動器科学研究会
- Place of Presentation
  みなみホール(鹿児島県　鹿児島市)
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] BMPにより増強される軟骨肉腫細胞の浸潤能を発現誘導されたPEG10は制御する2015
- Author(s)
  篠原直弘,前田真吾,八尋雄平,今村　勝行,横内雅博,河村一郎,石堂康弘,小宮節郎
- Organizer
  第３３回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル(東京都　新宿区)
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] インプリンティング遺伝子Peg10の軟骨細胞分化における役割2014
- Author(s)
  篠原直弘、前田真吾、今村勝行、松山金寛、横内雅博、石堂康弘、小宮節郎
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] インプリンティング遺伝子Peg10はBMP-2誘導の骨・軟骨細胞分化を促進する2013
- Author(s)
  篠原直弘、前田真吾、今村勝行、松山金寛、河村一郎、横内雅博、石堂康弘、小宮節郎
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] インプリンティング遺伝子Peg10の骨芽細胞と軟骨細胞の分化への関与2013
- Author(s)
  篠原直弘、前田真吾、今村勝行、松山金寛、河村一郎、横内雅博、石堂康弘、小宮節郎
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] 超音波と Bubble Liposome を併用したドキソルビシンのマウス骨肉腫細胞に対する抗腫瘍効果2012
- Author(s)
  上野宜功, 園田祥三, 鈴木亮, 横内雅博, 川添泰臣, 丸山一雄, 坂本泰二, 小宮節郎
- Organizer
  日本生体電気・物理刺激研究会
- Place of Presentation
  於鹿児島
- Data Source
  KAKENHI-PROJECT-22591662
[Presentation] 超音波を使用した新規抗癌剤デリバリーシステムについての実験的検討2011
- Author(s)
  横内雅博, 上野宜功, 川添泰臣, 永野聡, 小宮節郎, 園田祥三, 坂本泰二, 鈴木亮, 丸山和雄
- Organizer
  日本癌治療学会
- Place of Presentation
  於名古屋
- Data Source
  KAKENHI-PROJECT-22591662
[Presentation] 超音波を使用した新規抗癌剤デリバリーシステムについての実験的検討2011
- Author(s)
  横内雅博
- Organizer
  第49回日本癌治療学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22591662

1. KOMIYA Setsurou (30178371)

# of Collaborated Projects: 8 results

# of Collaborated Products: 31 results
2. HAYASHI Kyoji (50325784)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. YONE Kazunori (40182844)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. Maeda Shingo (60353463)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
5. NAGAMINE Tomonori (10359979)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SETOGUCHI Takao (40423727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ZEMMYO Michihisa (10289465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. Ishidou Yasuhiro (10300740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
9. ARISHIMA Yoshiya (90336339)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MATSUNAGA Shunji (90229500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 佐々木裕美 (60773380)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. UENO Yoshinori

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Yokouchi Masahiro 横内 雅博

YOKOUCHI Masahiro 横内 雅博

横内 政博 ヨコウチ マサヒロ

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軟骨肉腫診断マーカーと治療標的候補としてのTGF-βとPEG10の機能解析Principal Investigator

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Target gene screening of TGF-b signaling and functional analysis for differentiation-inducing therapy of chondrosarcomaPrincipal Investigator

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Anti-tumor effect of doxorubicin with bubble liposome and ultrasoundPrincipal Investigator

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Targeting of osteosarcoma and soft tissue sarcoma initiating cells

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Manifestation of HMGB-1 and Preventive Effect of Degeneration on Spinal Cord Following Acute Traumatic Injury.

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The inhibitory effects of ubiuitin system in signal transduction of osteosarcoma

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The role of ubiquitination in signal transduction of OsteosarcomaPrincipal Investigator

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Preventive effect of erythropoietin on spinal cord degeneration following acute traumatic injury

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[Journal Article] SnoN suppresses maturation of chondrocytes by mediating signal cross-talk between transforming growth factor-β and bone morphogenetic protein pathways.2012

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[Journal Article] 分子レベルからみた整形外科疾患(シリーズ IX) Bubble liposome と超音波を併用した drug delivery system の開発2012

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[Journal Article] Clinical implications of determination of safe surgical margins by using a combination of CT and 18FDG-positron emission tomography in soft tissue sarcoma2011

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[Journal Article] Clinical implications of determination of safe surgical margins by using a combination of CT and 18FDG-positron emission tomography in soft tissue sarcoma.2011

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[Journal Article] Combination of ultrasound and bubble liposome enhance the effect of doxorubicin and inhibit murine osteosarcoma growth2011

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[Journal Article] Gadd45β expression in chondrosarcoma: a pilot study for diagnostic and biological implications in histological grading2010

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Yokouchi Masahiro 横内雅博

YOKOUCHI Masahiro 横内雅博

横内政博ヨコウチマサヒロ