Iwanaga Yoshitaka 岩永善高

… Alternative Names

IWANAGA Yoshitaka 岩永善高

岩永善高イワナガヨシタカ

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Researcher Number	80360816
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立循環器病研究センター, オープンイノベーションセンター, 客員部長
Affiliation (based on the past Project Information) *help	2022 – 2024: 国立研究開発法人国立循環器病研究センター, オープンイノベーションセンター, 客員部長 2016 – 2018: 近畿大学, 医学部, 准教授 2012: 近畿大学, 医学部, 准教授 2010 – 2011: 近畿大学, 医学部, 講師 2007: Kinki University, School of Medicine, Lecturer … More 2006: 京都大学, 医学研究科, 講師 2004: 循環器病センター, 研究員 2003: 国立循環器病センター研究所, 病因部, 室長 Less
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Cardiovascular medicine Except Principal Investigator Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
Keywords	Principal Investigator 心不全 / 交感神経 / 急性腎障害 / バゾプレッシン系 / 心腎脳連関 / 交感神経系 / バゾプレッシン / Adipose / Heart Failure / 脂肪細胞 … More / 線維化 / 心肥大 / 分子心臓病態学 / マトリックス蛋白 / 遺伝子治療 … More Except Principal Investigator 機械学習 / J-AB / 心房細動 / 合併症 / カテーテルアブレーション / ビッグデータ Less

ビッグデータ・機械学習を用いたアブレーション治療の有効性・安全性予測モデルの作成
- Principal Investigator
  
  草野研吾
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
- Research Institution
  National Cardiovascular Center Research Institute
the crosstalk between the vasopressin system and the sympathetic nervous system from the viewpoint of the heart-kidney-brain networkPrincipal Investigator
- Principal Investigator
  
  IWANAGA Yoshitaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kindai University
Elucidation of novel mechanism in cardiac fibrosisPrincipal Investigator
- Principal Investigator
  
  IWANAGA Yoshitaka
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kinki University
Role of brain-adipose axis in heart failure and its application for novel therapy of heart failurePrincipal Investigator
- Principal Investigator
  
  IWANAGA Yoshitaka
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kinki University
  Kyoto University
新しい心不全遺伝子治療の研究―分泌型マトリックス蛋白の役割の検討より―Principal Investigator
- Principal Investigator
  
  岩永善高
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National Cardiovascular Center Research Institute

All 2025 2024 2023 2022 2019 2017 2013 2012 2011 2010 2007 2006

All Journal Article Presentation

[Journal Article] Assessment of the safety and efficacy of catheter ablation for atrial fibrillation in very elderly patients: insight from the national prospective registry study2025
- Author(s)
  Koichi Inoue 1, Michikazu Nakai 2, Teiichi Yamane 3, Kengo Kusano 4, Seiji Takatsuki 5, Kazuhiro Satomi 6, Yoshitaka Iwanaga 2, Koshiro Kanaoka 2, Reina Tonegawa-Kuji 2, Yoko Sumita 2, Misa Takegami 7 8, Yoko M Nakao 2 9, Akihiko Nogami 10, Yoshihiro Miyamoto 2, Wataru Shimizu 11
- Journal Title
  
  Eur Heart J Qual Care Clin Outcomes
  
  Volume: 11 Issue: 3 Pages: 323-333
- DOI
  10.1093/ehjqcco/qcae072
- Data Source
  KAKENHI-PROJECT-23K24623
[Journal Article] Impact of Being Underweight on the Safety and Efficacy of Atrial Fibrillation Ablation: An Analysis From the Japanese Catheter Ablation Registry.2024
- Author(s)
  Nakashima T, Tonegawa-Kuji R, Nakamura K, Kanaoka K, Nakai M, Nagase M, Yamaura M, Ido T, Takahashi S, Aoyama T, Nagashima K, Masuda M, Yamashita S, Miyamoto K, Iwasaki YK, Satomi K, Takatsuki S, Inoue K, Kusano K, Yamane T, Shimizu W
- Journal Title
  
  Circ Arrhythm Electrophysiol
  
  Volume: 17 Issue: 2 Pages: 408-410
- DOI
  10.1016/j.jacep.2024.10.011
- Data Source
  KAKENHI-PROJECT-23K24623
[Journal Article] Impact of Low Body Mass Index on Cardiac Tamponade During Catheter Ablation for Atrial Fibrillation2023
- Author(s)
  Tonegawa-Kuji Reina、Nakai Michikazu、Kanaoka Koshiro、Sumita Yoko、Miyamoto Yoshihiro、Kusano Kengo、Iwanaga Yoshitaka、Yamane Teiichi
- Journal Title
  
  JACC: Clinical Electrophysiology
  
  Volume: 9 Issue: 2 Pages: 200-208
- DOI
  10.1016/j.jacep.2022.08.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16155, KAKENHI-PROJECT-23K24623
[Journal Article] The Japanese Catheter Ablation Registry (J-AB): Annual report in 20202022
- Author(s)
  Kengo Kusano 1, Teiichi Yamane 2, Koichi Inoue 3, Misa Takegami 4, Yoko M Nakao 5, Michikazu Nakai 5, Koshiro Kanaoka 5, Reina Tonegawa-Kuji 5, Koji Miyamoto 1, Yu-Ki Iwasaki 6, Seiji Takatsuki 7, Kohki Nakamura 8, Yoshitaka Iwanaga 5, Wataru Shimizu 6; J‐AB registry investigators
- Journal Title
  
  J Arrhythm .
  
  Volume: 38 Issue: 5 Pages: 675-681
- DOI
  10.1002/joa3.12772
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24623
[Journal Article] Modulation of Sympathetic Activity and Innervation With Chronic Ivabradine and β-Blocker Therapies: Analysis of Hypertensive Rats With Heart Failure2019
- Author(s)
  Kakehi Kazuyoshi、Iwanaga Yoshitaka、Watanabe Heitaro、Sonobe Takashi、Akiyama Tsuyoshi、Shimizu Shuji、Yamamoto Hiromi、Miyazaki Shunichi
- Journal Title
  
  Journal of Cardiovascular Pharmacology and Therapeutics
  
  Volume: in press Issue: 4 Pages: 387-396
- DOI
  10.1177/1074248419829168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09465, KAKENHI-PROJECT-17K11604
[Journal Article] Metastasis-associated protein, S100A4 mediates cardiac fibrosis potentially through the modulation of p53 in cardiac fibroblasts2013
- Author(s)
  Yodo Tamaki, Yoshitaka Iwanaga (Corresponding Author), Shinichiro Niizuma, Tsuneaki Kawashima, Takao Kato, Yasutaka Inuzuka, Takahiro Horie, Hanako Morooka, Toru Takase, Yasumitsu Akahashi, Kazuhiro Kobuke, Koh Ono, Tetsuo Shioi, Soren P Sheikh, Noona Ambartsumian, Eugene Lukanidin, Taka-aki Koshimizu, Shunichi Miyazaki, Takeshi Kimura
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 57 Pages: 72-81
- Data Source
  KAKENHI-PROJECT-22590815
[Journal Article] Chronic Administration of Oral Vasopressin Type 2 Receptor Antagonist, Tolvaptan Exerts Both Myocardial and Renal Protective Effects in Rats with Hypertensive Heart Failure2012
- Author(s)
  Hanako Morooka, Yoshitaka Iwanaga (Corresponding Author), Yodo Tamaki, Toru Takase, Yasumitsu Akahoshi, Yasumasa Nakano, Hiroyuki Fujiki, Shunichi Miyazaki
- Journal Title
  
  Circ Heart Fail
  
  Volume: 5 Pages: 484-492
- Data Source
  KAKENHI-PROJECT-22590815
[Journal Article] BNP in Overweight and Obese Patients with Heart Failure : An Analysis Based on the BNP-LV Diastolic Wall Stress Relationship2007
- Author(s)
  Iwanaga Y.
- Journal Title
  
  Journal of Cardiac Failure 13
  
  Pages: 663-667
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590774
[Journal Article] BNP in Overweight and Obese Patients with Heart Failure:An Analysis Based on the BNP-LV Diastolic Wall Stress Relationship2007
- Author(s)
  Iwanaga Y, et. al.
- Journal Title
  
  Journal of Cardiac Failure 13
  
  Pages: 663-667
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590774
[Journal Article] BNP in Overweight and Obese Patients with Heart Failure:An AnalysisBased on the BNP-LV Diastolic Wall Stress Relationship2007
- Author(s)
  Iwanaga Y, et. al.
- Journal Title
  
  Journal of Cardiac Failure 13
  
  Pages: 663-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590774
[Journal Article] Down-regulation of Cardiac Apelin System in Hypertrophied and Failing Hearts : Possible Role of Angiotensin II-Angiotensin Type 1 Receptor System2006
- Author(s)
  Iwanaga Y.
- Journal Title
  
  Journal of Molecular and Cellular Cardiology 41
  
  Pages: 789-806
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590774
[Journal Article] Down-Regulation of Cardiac Apelin System in Hypertrophied and Failing Hearts : Possible Role of Angiotensin II - Angiotensin Type 1 Receptor System.2006
- Author(s)
  Yoshitaka Iwanaga, Yasuki Kihara, Hiroyuki Takenaka, Toru Kita.
- Journal Title
  
  Journal of Molecular and Cellular Cardiology 41
  
  Pages: 798-806
- Data Source
  KAKENHI-PROJECT-18590774
[Journal Article] Down-regulation of Cardiac Apelin System in Hypertrophied and-Failing Hearts:Possible Role of Angiotensin II-Angiotensin Type 1 Receptor System2006
- Author(s)
  Iwanaga Y, et. al.
- Journal Title
  
  Journal of Molecular and Cellular Cardiology 41
  
  Pages: 789-806
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590774
[Presentation] Vasopressin type 1a receptor deficiency prevents sepsis-induced cardiac dysfunction and improves the survival independently of renal sympathetic denervation.2017
- Author(s)
  Iwanaga Y, Kakehi K, Yamamoto H, Miyazaki S.
- Organizer
  90th AHA (American Heart Association) Scientific Sessions.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09465
[Presentation] 腎臓交感神経切除術の心不全治療への応用：基礎研究から臨床応用を考える.2017
- Author(s)
  岩永善高、渡辺平太郎、山本裕美、宮崎俊一．
- Organizer
  第65回日本心臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09465
[Presentation] Different modulation of sympathetic activity by chronic ivabradine and beta blocker therapies: analysis in hypertensive heart failure rats.2017
- Author(s)
  Kakehi K, Iwanaga Y, Watanabe H, Yamamoto H, Miyazaki S.
- Organizer
  90th AHA (American Heart Association) Scientific Sessions.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09465
[Presentation] Does vasopressin type1a receptor antagonist exert beneficial effects or additive effects to type2 receptor antagonist, tolvaptan in heart failure animals?2013
- Author(s)
  Tomoyuki Ikeda, Yoshitaka Iwanaga
- Organizer
  第75回日本循環器学会総会
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-22590815
[Presentation] Interaction of S100A4 with p53 in fibroblasts modulates cardiac fibrosis through two distinct mechanisms2012
- Author(s)
  Yodo Tamaki, Yoshitaka Iwanaga
- Organizer
  ESC Congress 2012, Munich
- Place of Presentation
  Germany
- Data Source
  KAKENHI-PROJECT-22590815
[Presentation] Activation of p53 in Fibroblasts Suppresses Cardiac Fibrosis2012
- Author(s)
  Y.Tamaki, Y.Iwanaga, et al
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-03-17
- Data Source
  KAKENHI-PROJECT-22590815
[Presentation] Chronic administration of oral vasopressin type 2 receptor blocker, tolvaptan exerts both myocardial and renal protective effects in rats with hypertensive heart failure2011
- Author(s)
  Hanako Morooka, Yoshitaka Iwanaga
- Organizer
  85th AHA (American Heart Association) Scientific Sessions
- Place of Presentation
  Orland, USA
- Data Source
  KAKENHI-PROJECT-22590815
[Presentation] Vasopressin type la receptor deficiency prevents the onset of heart failure : possible link with myocardial fibrosis.2010
- Author(s)
  T.Takase, Y.Iwanaga, et al.
- Organizer
  84th AHA (American Heart Association) Scientific Sessions
- Place of Presentation
  Chicago, USA
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-22590815
[Presentation] Vasopressin type 1a receptor deficiency prevents the onset of heart failure: possible link with myocardial fibrosis2010
- Author(s)
  Toru Takase, Yoshitaka Iwanaga
- Organizer
  84th AHA (American Heart Association) Scientific Sessions
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-22590815
[Presentation] 内因性ペプタイド,アペリンの心不全治療への応用2007
- Author(s)
  岩永善高, ら
- Organizer
  アメリカ心臓病協会2007年次学術集会
- Place of Presentation
  米国,オーランド
- Year and Date
  2007-11-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590774
[Presentation] Chronic Administration of Endogenous Inotropic Peptide, Apelin, Prevents Left Ventricular Remodeling and Improves Survival in Hypertensive Rats with Heart Failure2007
- Author(s)
  Iwanaga Y.
- Organizer
  American Heart Association 2007 Annual Scientific Sessions
- Place of Presentation
  Orlando, USA
- Year and Date
  2007-04-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590774
[Presentation] 内因性ペプタイド、アペリンの心不全治療への応用2007
- Author(s)
  岩永善高, ら
- Organizer
  アメリカ心臓病協会2007年次学術集会
- Place of Presentation
  米国、オーランド
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-18590774

1. ONO Koh (00359275)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. KOSHIMIZU Taka-aki (20392491)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. SHIOI Tetsuo (50360095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 草野研吾 (60314689)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 山根禎一 (40297429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 清水渉 (50399606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 中井陸運 (50595147)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. YAMAMOTO hiromi

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 利根川玲奈

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Iwanaga Yoshitaka 岩永 善高

IWANAGA Yoshitaka 岩永 善高

岩永 善高 イワナガ ヨシタカ

Research Projects

Research Products

Co-Researchers

ビッグデータ・機械学習を用いたアブレーション治療の有効性・安全性予測モデルの作成

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

the crosstalk between the vasopressin system and the sympathetic nervous system from the viewpoint of the heart-kidney-brain networkPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of novel mechanism in cardiac fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of brain-adipose axis in heart failure and its application for novel therapy of heart failurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新しい心不全遺伝子治療の研究―分泌型マトリックス蛋白の役割の検討より―Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Assessment of the safety and efficacy of catheter ablation for atrial fibrillation in very elderly patients: insight from the national prospective registry study2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of Being Underweight on the Safety and Efficacy of Atrial Fibrillation Ablation: An Analysis From the Japanese Catheter Ablation Registry.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of Low Body Mass Index on Cardiac Tamponade During Catheter Ablation for Atrial Fibrillation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Japanese Catheter Ablation Registry (J-AB): Annual report in 20202022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modulation of Sympathetic Activity and Innervation With Chronic Ivabradine and β-Blocker Therapies: Analysis of Hypertensive Rats With Heart Failure2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metastasis-associated protein, S100A4 mediates cardiac fibrosis potentially through the modulation of p53 in cardiac fibroblasts2013

Author(s)

Journal Title

Data Source

[Journal Article] Chronic Administration of Oral Vasopressin Type 2 Receptor Antagonist, Tolvaptan Exerts Both Myocardial and Renal Protective Effects in Rats with Hypertensive Heart Failure2012

Author(s)

Journal Title

Data Source

[Journal Article] BNP in Overweight and Obese Patients with Heart Failure : An Analysis Based on the BNP-LV Diastolic Wall Stress Relationship2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] BNP in Overweight and Obese Patients with Heart Failure:An Analysis Based on the BNP-LV Diastolic Wall Stress Relationship2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] BNP in Overweight and Obese Patients with Heart Failure:An AnalysisBased on the BNP-LV Diastolic Wall Stress Relationship2007

Iwanaga Yoshitaka 岩永善高

IWANAGA Yoshitaka 岩永善高

岩永善高イワナガヨシタカ