Matsumoto Kazuhiro 松本一宏

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MATSUMOTO Kazuhiro 松本一宏

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Researcher Number	80366153
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help	2019 – 2024: 慶應義塾大学, 医学部(信濃町), 講師 2016 – 2018: 慶應義塾大学, 医学部(信濃町), 助教 2015: 慶應義塾大学, 医学部, 助教 2012: 慶應義塾大学, 医学部, その他 2012: 慶應義塾大学, 医学部, 助教 2011 – 2012: 慶應義塾大学, 医学部, 共同研究員 2008 – 2009: Keio University, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related / Urology Except Principal Investigator Basic Section 56030:Urology-related / Urology / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator 筋層非浸潤性膀胱癌 / Mitomycin C / 酸化ストレス / Tadalafil / 膀胱癌 / 免疫治療 / 遺伝子治療 / PDE5阻害剤 / 酸化ストレス応答 / 間質性膀胱炎 … More / ドラッグ・リポジショニング / 膀胱内注入療法 / PDE5阻害薬 / 筋層非浸潤性性膀胱癌 / PDE５阻害薬 / 抗癌剤膀胱内注入 / マウス膀胱癌同所性モデル / PTEN / 非筋層浸潤性膀胱癌 / インターロイキン-15 … More Except Principal Investigator 細胞外マトリックス / 腎臓再生 / 上皮間葉転換 / 尿路上皮癌 / 膀胱癌 / CD163 / CD68 / urothelial carcinoma / UTUC / Immune microenvironment / FGFR3 / CD8 / CD204 / 抗炎症 / 抗線維化 / 腎不全 / 生体材料 / 治癒予測 / 超選択的副腎静脈サンプリング / 3Dモデル / 機能温存手術 / 原発性アルドステロン症 / がん組織不均一性 / 循環腫瘍細胞 / 膨張顕微鏡法 / 免疫微小環境 / 腫瘍内不均一性 / ライトシート顕微鏡 / RNAシークエンス / 免疫療法 / シークエンス / イメージング / 免疫治療 / 分子標的治療 / 腎細胞癌 / 組織修復 / 慢性腎不全 / スキャフォールド / 医療材料 / 腎臓 / 臓器再生 / 大動物 / 腎臓部分切除 / 脱細胞化 / 糸球体 / ユビキチン / 抗がん剤耐性 / FBXO32 / シスプラチン / 予後 / MCP-1 / 単球 / 好中球 / 喫煙 / MUC1 / バイオマーカー / 前立腺癌 / ケモカイン / 血管新生 / 耐性機序 / マウス膀胱癌同所性モデル / IL-15 / IL-21 / 膀胱内注入 / 遺伝子導入 / インターロイキン21 Less

Basic research focusing on correlation between tumor associated macrophage and peripheral monocyte count
- Principal Investigator
  
  北岡壮太郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Keio University
Prediction of biochemical cure after adrenal sparing surgery for primary aldosteronism
- Principal Investigator
  
  武田利和
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Keio University
Elucidationof of Kidney Repair Mechanisms Focusing on the Extracellular Environment and Development of Organ Regeneration Induction Methods
- Principal Investigator
  
  八木洋
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Keio University
酸化ストレス応答に着目した間質性膀胱炎の発症メカニズム解明と治療法の開発Principal Investigator
- Principal Investigator
  
  松本一宏
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Keio University
Targeting cancer stem cells and spatial niches in kidney cancer: Unravelling intratumoral heterogeneity
- Principal Investigator
  
  TANAKA NOBUYUKI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Keio University
Drug repositioning approaches for novel intravesical treatment against bladder cancerPrincipal Investigator
- Principal Investigator
  
  MATSUMOTO Kazuhiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Keio University
Novel Renal Regeneration Technology based on Self-Remodeling Capacity using Innovative Biomaterial
- Principal Investigator
  
  Yagi Hiroshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Keio University
Role of chemokine in urothelial cancer progression
- Principal Investigator
  
  MIYAJIMA Akira
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Tokai University
  Keio University
Tumor microenvironment and ubiquitin system in platinum resistance urothelial carcinoma
- Principal Investigator
  
  TANAKA NOBUYUKI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Keio University
Liposomal PTEN Gene Therapy in an Orthotopic Bladder Cancer Modeland Prevention of Tumor Invasion and MetastasisPrincipal Investigator
- Principal Investigator
  
  MATSUMOTO Kazuhiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Keio University
Liposomal IL-21/IL-15 Gene Therapy in an Orthotopic Bladder Cancer Model and Prevention of Tumor Invasion and Metastasis
- Principal Investigator
  
  MATSUSHIMA Masashi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Keio University
Liposomal Interleukin-15 Gene Therapy in an Orthotopic Bladder Cancer Model and Acquirement of Immunologic MemoryPrincipal Investigator
- Principal Investigator
  
  MATSUMOTO Kazuhiro
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Keio University

All 2020 2019 2018 2016 2015 2014 2009 2008

All Journal Article Presentation

[Journal Article] Vasohibin-1 as a novel microenvironmental biomarker for patient risk reclassification in low-risk prostate cancer2018
- Author(s)
  Kobayashi Hiroaki, Kosaka Takeo, Mikami Shuji, Miyazaki Yasumasa, Matsumoto Kazuhiro, Kikuchi Eiji, Miyajima Akira, Kameyama Kaori, Sato Yasufumi, Oya Mototsugu
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 12 Pages: 10203-10210
- DOI
  10.18632/oncotarget.23011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08657, KAKENHI-PROJECT-17K11158, KAKENHI-PROJECT-15K10609
[Journal Article] The Preoperative Neutrophil-to-lymphocyte Ratio is a Novel Biomarker for Predicting Worse Clinical Outcomes in Non-muscle Invasive Bladder Cancer Patients with a Previous History of Smoking.2016
- Author(s)
  Ogihara K, Kikuchi E, Yuge K, Yanai Y, Matsumoto K, Miyajima A, Asakura H, Oya M.
- Journal Title
  
  Annals of surgical oncology
  
  Volume: 23 Issue: S5 Pages: 1039-1047
- DOI
  10.1245/s10434-016-5578-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10609
[Journal Article] Plasma fibrinogen level: An independent prognostic factor for disease-free survival and cancer-specific survival in patients with localized renal cell carcinoma2016
- Author(s)
  Obata J, Tanaka N, Mizuno R, Kanao K, Mikami S, Matsumoto K, Kosaka T, Kikuchi E, Jinzaki M, Oya M
- Journal Title
  
  BJU Int
  
  Volume: Epub ahead of print Issue: 4 Pages: 598-603
- DOI
  10.1111/bju.13414
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04977, KAKENHI-PROJECT-26462429
[Journal Article] Comparison of outcomes between ultrasonography and cystoscopy in the surveillance of patients with initially diagnosed TaG1-2 bladder cancers: A matched-pair analysis2015
- Author(s)
  Naoya Niwa, Kazuhiro Matsumoto, Nozomi Hayakawa, Yujiro Ito, Takahiro Maeda, Seiya Akatsuka, Takeshi Masuda, So Nakamura, Nobuyuki Tanaka
- Journal Title
  
  Urologic Oncology: Seminars and Original Investigations
  
  Volume: 33 Issue: 9 Pages: 386.e15-386.e21
- DOI
  10.1016/j.urolonc.2015.04.018
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462429, KAKENHI-PROJECT-15K20110
[Journal Article] Impact of Combined Use of Blood-based Inflammatory Markers on Patients with Upper Tract Urothelial Carcinoma Following Radical Nephroureterectomy: Proposal of a Cumulative Marker Score as a Novel Predictive Tool for Prognosis2015
- Author(s)
  Nobuyuki Tanaka, Eiji Kikuchi, Kent Kanao, Kazuhiro Matsumoto, Suguru Shirotake, Yasumasa Miyazaki, Hiroaki Kobayashi, Gou Kaneko, Masayuki Hagiwara, Hiroki Ide, Jun Obata, Katsura Hoshino, Nozomi Hayakawa, Takeo Kosaka, Satoshi Hara, Ken Nakagawa, Masahiro Jinzaki, Mototsugu Oya
- Journal Title
  
  European Urology Focus
  
  Volume: 1 Issue: 1 Pages: 54-63
- DOI
  10.1016/j.euf.2015.02.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462429
[Journal Article] A Multi-Institutional Validation of the Prognostic Value of the Neutrophil-to-Lymphocyte Ratio for Upper Tract Urothelial Carcinoma Treated with Radical Nephroureterectomy.2014
- Author(s)
  Tanaka N, Kikuchi E, Kanao K, Matsumoto K, Shirotake S, Miyazaki Y, Kobayashi H, Kaneko G, Hagiwara M, Ide H, Obata J, Hoshino K, Hayakawa N, Kosaka T, Hara S, Oyama M, Momma T, Nakajima Y, Jinzaki M, Oya M
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 21(12) Issue: 12 Pages: 4041-8
- DOI
  10.1245/s10434-014-3830-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390374, KAKENHI-PROJECT-26462429
[Presentation] Single-cell RNA-seq analysis of intra-tumor heterogeneity dynamics reveals the novel platinum resistance gene COX7B in patients with urinary bladder cancer2020
- Author(s)
  田中伸之、丹羽直也、本郷周、安水洋太、武田利和、松本一宏、森田伸也、小坂威雄、水野隆一、浅沼宏、Per Uhlen、大家基嗣
- Organizer
  第108回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-19H03792
[Presentation] 3次元ライトシート顕微鏡を用いた次世代泌尿器癌イメージング:腫瘍内不均一性の可視化2019
- Author(s)
  田中伸之、三上修治、桝田司、武田利和、松本一宏、森田伸也、小坂威雄、浅沼宏、水野隆一、大家基嗣
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03792
[Presentation] ドラッグ・リポジショニングを用いた、筋層非浸潤性膀胱癌に対する新規膀胱内注入療法の開発2019
- Author(s)
  松本一宏
- Organizer
  第107回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-18K09179
[Presentation] マウス膀胱癌に対するInter leukin-15遺伝子治療2009
- Author(s)
  松本一宏、菊地栄次, 他
- Organizer
  第13回日本がん分子標的治療学会
- Place of Presentation
  徳島
- Year and Date
  2009-06-25
- Data Source
  KAKENHI-PROJECT-20791121
[Presentation] マウス膀胱癌に対するInterleukin-15遺伝子治療2009
- Author(s)
  松本一宏、菊地栄次、宮嶋哲、大家基嗣
- Organizer
  第13回日本がん分子標的治療学会
- Place of Presentation
  徳島
- Year and Date
  2009-06-25
- Data Source
  KAKENHI-PROJECT-20791121
[Presentation] Intravesical Interleukin-15 Gene Therapy in an Orthotopic Bladder Cancer Model2009
- Author(s)
  Matsumoto, K., Kikuchi, E., Horinaga, M., Miyajima, A., Nakagawa, K., Oya, M.
- Organizer
  The 105th annual meeting of American Urological Association
- Place of Presentation
  Chicago
- Year and Date
  2009-04-27
- Data Source
  KAKENHI-PROJECT-20791121
[Presentation] Transduction of murine bladder cancer cells with interleukin-15 gene induces antitumor effects2008
- Author(s)
  松本一宏、菊地栄次, 他
- Organizer
  第67回日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20791121
[Presentation] 膀胱癌に対するInterbukin-15遺伝子導入2008
- Author(s)
  松本一宏、菊地栄次, 他
- Organizer
  第96回日本泌尿器科学会
- Place of Presentation
  横浜
- Year and Date
  2008-04-26
- Data Source
  KAKENHI-PROJECT-20791121
[Presentation] Transduction of murine bladder cancer cells with interleukin-15 gene induces antitumor effects2008
- Author(s)
  Matsumoto, K., Kikuchi, E., Horinaga, M., Kohno, H., Miyajima, A., Nakagawa, K., Nakashima, J., Oya, M.
- Organizer
  第67回癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20791121

1. KIKUCHI Eiji (10286552)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. OYA Mototsugu (00213885)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
3. 小坂威雄 (30445407)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
4. MIYAJIMA Akira (90245572)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TANAKA NOBUYUKI (60445244)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
6. 武田利和 (10383829)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. Yagi Hiroshi (20327547)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 足達俊吾 (90783803)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. MATSUSHIMA Masashi (00464850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 丹羽直也 (40626743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 五島直樹 (70215482)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 三上修治 (20338180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 水野隆一 (60383824)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. 安水洋太 (40464854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 北岡壮太郎 (90936387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 森田伸也 (10365364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 茂田啓介 (10649875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 宮島哲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsumoto Kazuhiro 松本 一宏

MATSUMOTO Kazuhiro 松本 一宏

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酸化ストレス応答に着目した間質性膀胱炎の発症メカニズム解明と治療法の開発Principal Investigator

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Drug repositioning approaches for novel intravesical treatment against bladder cancerPrincipal Investigator

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Liposomal PTEN Gene Therapy in an Orthotopic Bladder Cancer Modeland Prevention of Tumor Invasion and MetastasisPrincipal Investigator

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Liposomal Interleukin-15 Gene Therapy in an Orthotopic Bladder Cancer Model and Acquirement of Immunologic MemoryPrincipal Investigator

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[Journal Article] Vasohibin-1 as a novel microenvironmental biomarker for patient risk reclassification in low-risk prostate cancer2018

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[Journal Article] The Preoperative Neutrophil-to-lymphocyte Ratio is a Novel Biomarker for Predicting Worse Clinical Outcomes in Non-muscle Invasive Bladder Cancer Patients with a Previous History of Smoking.2016

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DOI

Data Source

[Journal Article] Plasma fibrinogen level: An independent prognostic factor for disease-free survival and cancer-specific survival in patients with localized renal cell carcinoma2016

Matsumoto Kazuhiro 松本一宏

MATSUMOTO Kazuhiro 松本一宏

[Presentation] 3次元ライトシート顕微鏡を用いた次世代泌尿器癌イメージング:腫瘍内不均一性の可視化2019