Yamauchi Akira 山内明

… Alternative Names

YAMAUCHI Akira 山内明

山内明ヤマウチアキラ

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Researcher Number	80372431
Other IDs
Affiliation (Current)	2025: 川崎医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 川崎医科大学, 医学部, 教授 2010 – 2015: 川崎医科大学, 医学部, 准教授 2007: 東大, 先端科学技術研究センター 2005 – 2006: 東京大学, 先端科学技術研究センター, 科学技術振興特任教員(特任助手)
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / 膠原病・アレルギー・感染症内科学 / Digestive surgery Except Principal Investigator Basic Section 57020:Oral pathobiological science-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 50010:Tumor biology-related / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 53010:Gastroenterology-related / Morphological basic dentistry / Hygiene and public health / Pediatrics
Keywords	Principal Investigator 走化性 / 膵癌 / 癌転移 / 脂質 / ケモカイン / 炎症 / 細胞走化性 / 免疫細胞 / 増殖抑制 / 転移 … More / リンパ組織 / S100タンパク質 / 活性酸素 / リンパ向性転移 / マイクロアレイ / 細胞動態 / S100 protein / リンパ内皮細胞 / 血清因子 / がん / 遊走 / 転移惹起因子 / 骨髄系細胞 / シグナル伝達 / 走化性因子 / 脂質メディエーター / GPCR / PAFR / FPR1 / FPR1-PAFRキメラ遺伝子 / PAF / IL-8 / fMLP / 脂質メディエータ / 好中球 / TAXIScan / KKチャンバー / 走化性制御 / 受容体会合分子 / 炎症・アレルギー / タクシスキャン法 / 好中球・好酸球 / ケモカイン受容体 / 新薬開発 / アレルギー … More Except Principal Investigator DKK3 / バイオマーカー / 頭頚部扁平上皮癌 / 癌関連遺伝子 / 口腔扁平上皮癌 / 遺伝子機能解析 / 口腔癌 / 頭頸部扁平上皮癌 / 好中球 / ナチュラルキラー細胞 / がん予防 / がん / 阻害作用 / 転移 / 受容体 / がん転移抑制タンパク質 / HRG / S100A8/A9 / NK細胞 / 細胞傷害性T細胞 / 免疫チェックポイント / 中皮腫 / 石綿 / 免疫チェックポイント阻害薬 / 抗腫瘍免疫 / 悪性中皮腫 / 相補性ペプチド / 阻害ペプチド / 免疫チェックポイント阻害剤 / 解糖系抑制 / 脂肪酸合成 / メタボローム解析 / 免疫担当細胞 / Warburug効果 / 糖代謝 / 2DG-PLGA / 2-depxy-D-glucose / ナノ粒子 / Warburg効果 / 肝細胞癌 / がん微小環境 / 腫瘍免疫 / 扁平上皮癌 / 癌 / 病理学 / がん関連遺伝子 / PAA / インターロイキン８ / 炎症 / 好酸球増多筋痛症 / 食品衛生 / 好酸球増多筋痛症(EMS) / サプリメント / IL-8 / EoL-3 / ケモカイン / ケモカインレセプター / 走化性 / 不純物 / 好酸球 / トリプトファン / 慢性肉芽腫症 / 活性酸素 / 膠原病学 / アレルギー / 小児免疫 Less

膵癌転移における核膜タンパク質の新たな機能を解明するPrincipal Investigator
- Principal Investigator
  
  山内明
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kawasaki Medical School
Researches for practical use of DKK3 complementary peptides.
- Principal Investigator
  
  片瀬直樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Nagasaki University
マルチオミックス解析に基づく次世代ナチュラルキラー細胞機能指標の開発
- Principal Investigator
  
  西村泰光
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kawasaki Medical School
S100A8/A9-向転移とHRG-抗転移の細胞間・分子間クロストークの解明
- Principal Investigator
  
  阪口政清
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Okayama University
悪性中皮腫の免疫チェックポイント阻害薬治療効果に関わる新規免疫機能遺伝子の探索
- Principal Investigator
  
  西村泰光
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kawasaki Medical School
Control of Head and neck cancer by inhibitory peptides for DKK3 functional domain.
- Principal Investigator
  
  KATASE Naoki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Nagasaki University
Why cancer cells metastasize to lymphatics from the early stage ?Principal Investigator
- Principal Investigator
  
  Yamauchi Akira
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kawasaki Medical School
Activation of tumor immunity by metabolic reprogramming in liver cancer microenvironment
- Principal Investigator
  
  Hino Keisuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kawasaki Medical School
Tumor control targeting specific cancer-associated gene, DKK3 in squamous cell carcinoma
- Principal Investigator
  
  KATASE Naoki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University
Explorative research of novel factors for pancreatic cancer metastasis and proliferation based on analysis of cell dynamicsPrincipal Investigator
- Principal Investigator
  
  Yamauchi Akira
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kawasaki Medical School
The elucidation of the mechanisms behind the allergic reaction induced by tryptophan supplement byproducts.
- Principal Investigator
  
  OKAMOTO Takeaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  Ehime University
Elucidating how cells migrating to chemoattractants determine the direction.Principal Investigator
- Principal Investigator
  
  YAMAUCHI Akira
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kawasaki Medical School
Modulation of mRNA splicing for the genetic diseases
- Principal Investigator
  
  KURIBAYASHI Futoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kawasaki Medical School
新開発の走化性測定装置を用いた好中球・好酸球の遊走制御分子の探索と新薬開発Principal Investigator
- Principal Investigator
  
  山内明
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo

[Book] Medical Science Digest Vol 49 No.4 2023年4月号2023
- Author(s)
  片瀬直樹, 西松伸一郎, 山内明, 岡野慎士, 藤田修一
- Total Pages
  3
- Publisher
  株式会社ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-20K09908
[Book] DKK3相補性ペプチドによる頭頚部癌制御 (Medical Science Digest Vol 49 No.4 2023年4月号)2023
- Author(s)
  片瀬直樹, 西松伸一郎, 山内明, 岡野慎士, 藤田修一
- Total Pages
  3
- Publisher
  株式会社ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-20K09908
[Book] 生物機能実験法2013
- Author(s)
  岡本威明、　山内明
- Publisher
  一般社団法人　生物機能研究所
- Data Source
  KAKENHI-PROJECT-24591473
[Book] 生物機能実験法2013
- Author(s)
  岡本威明、山内明
- Total Pages
  168
- Publisher
  一般社団法人　生物機能研究所
- Data Source
  KAKENHI-PROJECT-24591473
[Book] Functions of the phagocyte NADPH oxidase and Chronic Granulomatous Disease(CGD) Nova Science Publishers(In : Neutrophils : Lifespan, Functions and Roles in Disease)2010
- Author(s)
  Akira Yamauchi and Futoshi Kuribayashi
- Data Source
  KAKENHI-PROJECT-21591365
[Book] Neutrophils : Lifespan, Functions and Roles in Disease2010
- Author(s)
  Akira Yamauchi, Futoshi Kuribayashi
- Total Pages
  7
- Publisher
  Nova Science Publishers(査読有り Accepted for publication in December 19, 2009)
- Data Source
  KAKENHI-PROJECT-21591365
[Journal Article] Lysyl oxidase-like 4 promotes the invasiveness of triple-negative breast cancer cells by orchestrating the invasive machinery formed by annexin A2 and S100A11 on the cell surface2024
- Author(s)
  Takahashi Tetta、Tomonobu Nahoko、Kinoshita Rie、Yamamoto Ken-ichi、Murata Hitoshi、Komalasari Ni Luh Gede Yoni、...、Honjo Tomoko、Sakaguchi Yoshihiko、Yamauchi Akira、Kuribayashi Futoshi、Kondo Eisaku、Inoue Yusuke、Futami Junichiro、Toyooka Shinichi、Zamami Yoshito、Sakaguchi Masakiyo
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 14 Pages: 1371342-1371342
- DOI
  10.3389/fonc.2024.1371342
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-22K07074, KAKENHI-PROJECT-23K06717, KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K27439
[Journal Article] DKK3 expression is correlated with poorer prognosis in head and neck squamous cell carcinoma: A bioinformatics study based on the TCGA database2023
- Author(s)
  Katase Naoki、Nishimatsu Shin-ichiro、Yamauchi Akira、Okano Shinji、Fujita Shuichi
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 65 Issue: 4 Pages: 334-346
- DOI
  10.1016/j.job.2023.09.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K10130, KAKENHI-PROJECT-20K09908
[Journal Article] DKK3/CKAP4 axis is associated with advanced stage and poorer prognosis in oral cancer.2023
- Author(s)
  Katase N, Kudo K, Ogawa K, Sakamoto Y, Nishimatsu S, Yamauchi A, Fujita S.
- Journal Title
  
  Oral Dis.
  
  Volume: 29(8) Issue: 8 Pages: 3193-3204
- DOI
  10.1111/odi.14277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09908
[Journal Article] Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that is dependent on the enzymatic activity that targets the cell-surface annexin A22023
- Author(s)
  Sakaguchi, M., Komalasari, N. L. G. Y., Tomonobu, N., Kinoshita, R., Chen, Y., Sakaguchi, Y., Gohara, Y., Jiang, F., Yamamoto, K., Murata, H., Ruma, I. M. W., Sumardika, I. W., Zhou, J., Yamauchi, A., Kuribayashi, F., Inoue, Y., Toyooka, S.
- Journal Title
  
  Front. Oncol.
  
  Volume: 13 Pages: 1142907-1142907
- DOI
  10.3389/fonc.2023.1142907
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07074, KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-22K06884, KAKENHI-PROJECT-23K06717, KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-23K27439
[Journal Article] Establishment of anti-DKK3 peptide for the cancer control in head and neck squamous cell carcinoma (HNSCC).2022
- Author(s)
  Katase N, Nishimatsu SI, Yamauchi A, Okano S, Fujita S.
- Journal Title
  
  Cancer Cell Int.
  
  Volume: 22(1)352 Issue: 1
- DOI
  10.1186/s12935-022-02783-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09908
[Journal Article] Fine definition of the epitopes on the human gp91 phox/NOX2 for the monoclonal antibodies CL-5 and 482022
- Author(s)
  Kawai C, Miyano K, Okamoto S, Yamauchi A, Kuribayashi F.
- Journal Title
  
  Journal of Immunological Methods
  
  Volume: 501 Pages: 113213-113213
- DOI
  10.1016/j.jim.2021.113213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07676
[Journal Article] The downregulation of NADPH oxidase Nox4 during hypoxia in hemangioendothelioma cells: a possible role of p22 phox on Nox4 protein stability2021
- Author(s)
  Miyano K, Okamoto S, Yamauchi A, Kawai C, Kajikawa M, Kiyohara T, Itsumi M, Taura M, Kuribayashi F.
- Journal Title
  
  Free Radical Research
  
  Volume: 55 Issue: 9-10 Pages: 996-1004
- DOI
  10.1080/10715762.2021.2009116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07676
[Journal Article] Nanoparticle-Mediated Delivery of 2-Deoxy-D-Glucose Induces Antitumor Immunity and Cytotoxicity in Liver Tumors in Mice2021
- Author(s)
  Sasaki Kyo、Nishina Sohji、Yamauchi Akira、Fukuda Kotaro、Hara Yuichi、Yamamura Masahiro、Egashira Kensuke、Hino Keisuke
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 11 Issue: 3 Pages: 739-762
- DOI
  10.1016/j.jcmgh.2020.10.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-19H03644, KAKENHI-PROJECT-18K07923, KAKENHI-PROJECT-21K07995
[Journal Article] Inhibitory Effect of Eicosapentaenoic Acid on the Migration of the Esophageal Squamous Cell Carcinoma Cell Line TE-12020
- Author(s)
  KUBOTA HISAKO、HIRAI TOSHIHIRO、YAMAUCHI AKIRA、OGO AYAKO、MATSUMOTO HIDEO、UENO TOMIO
- Journal Title
  
  Anticancer Research
  
  Volume: 40 Issue: 9 Pages: 5043-5048
- DOI
  10.21873/anticanres.14507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07676
[Journal Article] The NADPH oxidase NOX4 promotes the directed migration of endothelial cells by stabilizing vascular endothelial growth factor receptor 2 protein2020
- Author(s)
  Miyano Kei、Okamoto Shuichiro、Yamauchi Akira、Kawai Chikage、Kajikawa Mizuho、Kiyohara Takuya、Tamura Minoru、Taura Masahiko、Kuribayashi Futoshi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 33 Pages: 11877-11890
- DOI
  10.1074/jbc.ra120.014723
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07676
[Journal Article] The rRNA synthesis inhibitor CX-5461 may induce autophagy that inhibits anticancer drug-induced cell damage to leukemia cells2020
- Author(s)
  Okamoto Shuichiro、Miyano Kei、Kajikawa Mizuho、Yamauchi Akira、Kuribayashi Futoshi
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 84 Issue: 11 Pages: 2319-2326
- DOI
  10.1080/09168451.2020.1801378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-18K07804
[Journal Article] Constitutive activity of NADPH oxidase 1 (Nox1) that promotes its own activity suppresses the colon epithelial cell migration2020
- Author(s)
  Miyano Kei、Okamoto Shuichiro、Yamauchi Akira、Kajikawa Mizuho、Kiyohara Takuya、Taura Masahiko、Kawai Chikage、Kuribayashi Futoshi
- Journal Title
  
  Free Radical Research
  
  Volume: 54 Issue: 8-9 Pages: 640-648
- DOI
  10.1080/10715762.2020.1823383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-18K07804
[Journal Article] Neuroplastinβ-mediated upregulation of solute carrier family 22 member 18 antisense (SLC22A18AS) plays a crucial role in the epithelial-mesenchymal transition, leading to lung cancer cells' enhanced motility2020
- Author(s)
  Bajkowska Karolina、Sumardika I. Wayan、Tomonobu Nahoko、Chen Youyi、Yamamoto Ken-ichi、Kinoshita Rie、Murata Hitoshi、Gede Yoni Komalasari Ni Luh、Jiang Fan、Yamauchi Akira、Winarsa Ruma I. Made、Kasano-Camones Carlos Ichiro、Inoue Yusuke、Sakaguchi Masakiyo
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 22 Pages: 100768-100768
- DOI
  10.1016/j.bbrep.2020.100768
- NAID
  120006890008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
[Journal Article] DKK3 knockdown confers negative effects on malignant potency of head and neck squamous cell carcinoma cells via PI3K/Akt signal and MAPK pathways.2019
- Author(s)
  Katase N, Nishimatsu S, Yamauchi A, Yamamura M, Fujita S.
- Journal Title
  
  Int J Oncol.
  
  Volume: 54(3) Pages: 1021-1032
- DOI
  10.3892/ijo.2018.4667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11470
[Journal Article] Critical role of the MCAM-ETV4 axis triggered by extracellular S100A8/A9 in breast cancer aggressiveness.2019
- Author(s)
  Chen Y, Sumardika IW, Tomonobu N, Kinoshita R, Inoue Y, Iioka H, Mitsui Y, Saito K, Ruma IMW, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Futami J, Kubo M, Putranto EW, Murakami T, Liu M, Hibino T, Nishibori M, Kondo E, Toyooka S, Sakaguchi M.
- Journal Title
  
  Neoplasia.
  
  Volume: 21(7) Issue: 7 Pages: 627-640
- DOI
  10.1016/j.neo.2019.04.006
- NAID
  120006948963
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08276, KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] Dipeptidyl Peptidase 4 Inhibitors Reduce Hepatocellular Carcinoma by Activating Lymphocyte Chemotaxis in Mice2019
- Author(s)
  Nishina, S. Yamauchi, A. Kawaguchi, T. Kaku, K. Goto, M. Sasaki, K. Hara, Y. Tomiyama, Y. Kuribayashi, F. Torimura, T. Hino, K.
- Journal Title
  
  Cell Mol Gastroenterol Hepatol
  
  Volume: 7 Issue: 1 Pages: 115-134
- DOI
  10.1016/j.jcmgh.2018.08.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03644
[Journal Article] Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion.2019
- Author(s)
  Chen Y, Sumardika IW, Tomonobu N, Winarsa Ruma IM, Kinoshita R, Kondo E, Inoue Y, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Liu M, Futami J, Sasai K, Katayama H, Kubo M, Putranto EW, Hibino T, Sun B, Nishibori M, Toyooka S, Sakaguchi M
- Journal Title
  
  Cancer Lett.
  
  Volume: - Pages: 178-190
- DOI
  10.1016/j.canlet.2019.03.023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] Convenient methodology for extraction and subsequent selective propagation of mouse melanocytes in culture from adult mouse skin tissue.2019
- Author(s)
  Tomonobu N, Kinoshita R, Sumardika IW, Chen Y, Inoue Y, Yamauchi A, Yamamoto KI, Murata H, Sakaguchi M
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: - Pages: 100619-100619
- DOI
  10.1016/j.bbrep.2019.100619
- NAID
  120006948964
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts2019
- Author(s)
  Mitsui Yosuke、Tomonobu Nahoko、Watanabe Masami、Kinoshita Rie、Sumardika I Wayan、Youyi Chen、Murata Hitoshi et al.
- Journal Title
  
  Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
  
  Volume: 27 Issue: 8 Pages: 945-956
- DOI
  10.3727/096504019x15555408784978
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-19K16714, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] Newly developed anti-S100A8/A9 monoclonal antibody efficiently prevents lung tropic cancer metastasis.2018
- Author(s)
  Kinoshita R, Sato H, Yamauchi A, Takahashi Y, Inoue Y, Sumardika IW, Chen Y, Tomonobu N, Araki K, Shien K, Tomida S, Torigoe H, Namba K, Kurihara E, Ogoshi Y, Murata H, Yamamoto KI, Futami J, Putranto EW, Ruma IMW, Yamamoto H, Soh J, Hibino T, Nishibori M, Kondo E, Toyooka S, Sakaguchi M.
- Journal Title
  
  Int J Cancer.
  
  Volume: 印刷中 Issue: 2 Pages: 569-575
- DOI
  10.1002/ijc.31982
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] Monoclonal antibody 7D5 recognizes the R147 epitope on the gp91phox , phagocyte flavocytochrome b558 large subunit.2018
- Author(s)
  Kawai C, Yamauchi A, Kuribayashi F.
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 62 Issue: 4 Pages: 269-280
- DOI
  10.1111/1348-0421.12584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09671, KAKENHI-PROJECT-18K07804, KAKENHI-PROJECT-15K10201
[Journal Article] ｂ-1,3-galactosyl-O-glycosyl-glycoprotein ｂ-1,6-N-acetylglucosaminyltransferase 3 Increases MCAM Stability, Which Enhances S100A8/A9-Mediated Cancer Motility.2017
- Author(s)
  Sumardika I Wayan、Youyi Chen、Kondo Eisaku、Inoue Yusuke、Ruma I Made Winarsa、Murata Hitoshi、Kinoshita Rie、Yamamoto Ken-Ichi、Tomida Shuta、Shien Kazuhiko、Satoh Hiroki、Yamauchi Akira、Futami Junichiro、Putranto Endy Widya、Hibino Toshihiko、Toyooka Shinichi、Nishibori Masahiro、Sakaguchi Masakiyo
- Journal Title
  
  Oncology Reserch
  
  Volume: in press Issue: 3 Pages: 431-444
- DOI
  10.3727/096504017x15031557924123
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16K15245, KAKENHI-PROJECT-16K18440, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-15K10201, KAKENHI-PROJECT-18K15320
[Journal Article] Evaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device2017
- Author(s)
  Yamauchi A, Yamamura M, Katase N, Itadani M, Okada N, Kobiki K, Nakamura M, Yamaguchi Y, Kuribayashi F.
- Journal Title
  
  BMC CancerMar
  
  Volume: 31 Issue: 1 Pages: 234-244
- DOI
  10.1186/s12885-017-3218-4
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09671, KAKENHI-PROJECT-16K11470, KAKENHI-PROJECT-15K10201
[Journal Article] DKK3 Overexpression Increases Malignant Properties of Head and Neck Squamous Cell Carcinoma Cells.2017
- Author(s)
  Katase N, Nishimatsu SI, Yamauchi A, Yamamura M, Terada K, Itadani M, Okada N, Hassan NMM, Nagatsuka H, Ikeda T, Nohno T, Fujita S.
- Journal Title
  
  Oncology Research
  
  Volume: 26(1) Issue: 1 Pages: 45-58
- DOI
  10.3727/096504017x14926874596386
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11441, KAKENHI-PROJECT-16K11470, KAKENHI-PROJECT-15K10201
[Journal Article] ヒト好酸球性白血病由来細胞株EoL-3を用いた健康食品の安全性評価系の確立2016
- Author(s)
  田頭歩佳、加藤匡宏、山内加奈子、田中守、岡本威明
- Journal Title
  
  四国公衆衛生学会誌
  
  Volume: 61(1) Pages: 125-132
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460804
[Journal Article] MCAM, as a novel receptor for S100A8/A9, mediates progression of malignant melanoma through prominent activation of NF-κB and ROS formation upon ligand binding.2016
- Author(s)
  Ruma IM, Putranto EW, Kondo E, Murata H, Watanabe M, Huang P, Kinoshita R, Futami J, Inoue Y, Yamauchi A, Sumardika IW, Youyi C, Yamamoto K, Nasu Y, Nishibori M, Hibino T, Sakaguchi M.
- Journal Title
  
  Clin Exp Metastasis
  
  Volume: 33 Issue: 6 Pages: 609-627
- DOI
  10.1007/s10585-016-9801-2
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15K20093, KAKENHI-PROJECT-15K10201, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-16K15245
[Journal Article] Active Secretion of Dimerized S100A11 Induced by the Peroxisome in Mesothelioma Cells.2016
- Author(s)
  Saho S, Satoh H, Kondo E, Inoue Y, Yamauchi A, Murata H, Kinoshita R, Yamamoto KI, Futami J, Putranto EW, Ruma IM, Sumardika IW, Youyi C, Suzawa K, Yamamoto H, Soh J, Tomida S, Sakaguchi Y, Saito K, Iioka H, Huh NH, Toyooka S, Sakaguchi M.
- Journal Title
  
  Cancer Microenviron.
  
  Volume: 9 Issue: 2-3 Pages: 93-105
- DOI
  10.1007/s12307-016-0185-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01574, KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15K10201, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-16K08785, KAKENHI-PROJECT-16K15245
[Journal Article] Homodimerisation of the Lymph Vessel Endothelial Receptor LYVE-1 through a Redox-Labile Disulfide is Critical for Hyaluronan Binding in Lymphatic Endothelium.2016
- Author(s)
  Banerji S, Lawrance W, Metcalfe C, Briggs DC, Yamauchi A, Dushek O, van der Merwe PA, Day AJ, Jackson DG.
- Journal Title
  
  J Biol Chem
  
  Volume: 291(48) Issue: 48 Pages: 25004-25018
- DOI
  10.1074/jbc.m116.736926
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10201
[Journal Article] Increase of activated Treg in TIL in lung cancer and in vitro depletion of Treg by ADCC using an anti-human CCR4 mAb (KM2760).2015
- Author(s)
  Koji Kurose, Yoshihiro Ohue, Eiichi Sato Akira Yamauchi, Shingo Eikawa, Midori Isobe, Yumi Nishio, Akiko Uenaka, Mikio Oka, and Eiichi Nakayama.
- Journal Title
  
  J Thorac Oncol.
  
  Volume: 10 Issue: 1 Pages: 74-83
- DOI
  10.1097/jto.0000000000000364
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591473, KAKENHI-PROJECT-25430161, KAKENHI-PROJECT-26830117
[Journal Article] Systematic single cell analysis of migration and morphological changes of human neutrophils over stimulus concentration gradients.2014
- Author(s)
  Akira Yamauchi, Mikako Degawa-Yamauchi, Futoshi Kuribayashi, Shiro Kanegasaki, and Tomoko Tsuchiya
- Journal Title
  
  Journal of Immunological Methods
  
  Volume: 404 Pages: 59-70
- DOI
  10.1016/j.jim.2013.12.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591473, KAKENHI-PROJECT-24591563
[Journal Article] Relationship between macrophage differentiation and the chemotactic activity toward damaged myoblast cells.2013
- Author(s)
  Uchida M
- Journal Title
  
  J Immunol Methods
  
  Volume: 31 Issue: 1-2 Pages: 61-69
- DOI
  10.1016/j.jim.2013.04.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240089, KAKENHI-PROJECT-24500878, KAKENHI-PROJECT-24591473
[Journal Article] Review : The phagocyte NADPH oxidase and bacterial infections2012
- Author(s)
  Akira YAMAUCHI, Akitoyo ICHINOSE, Chikage KAWAI, and Futoshi KURIBAYASHI
- Journal Title
  
  Kawasaki Medical Journal
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591365
[Journal Article] The phagocyte NADPH oxidase and bacterial infections (Accepted for publication on the 17th of January in 2012)2012
- Author(s)
  Akira Yamauchi
- Journal Title
  
  Kawasaki Medical Journal
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591365
[Journal Article] A highly sensitive chemiluminescence assay for superoxide detection and chronic granulomatous disease diagnosis2011
- Author(s)
  Tsuyoshi Yamazaki, Chikage Kawai, Akira Yamauchi, and Futoshi Kuribayashi
- Journal Title
  
  Trop.Med.Health
  
  Volume: 39 Issue: 2 Pages: 41-45
- DOI
  10.2149/tmh.2011-08
- NAID
  10029327277
- ISSN
  1348-8945, 1349-4147
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591365
[Patent] 新規抗腫瘍剤2018
- Inventor(s)
  山内明、町支臣成
- Industrial Property Rights Holder
  学校法人川崎学園、学校法人福山大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-059074
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] Profile and relationship in altered expression of genes in peripheral blood lymphocytes observed in mesothelioma patients with partial response to nivolumab treatment2024
- Author(s)
  Y. Nishimura, S. Lee, A. Yamauchi, T. Kozuki, N. Fujimoto, and T. Otsuki
- Organizer
  63rd Annual Meeting of Society of Toxicology
- Data Source
  KAKENHI-PROJECT-23K24599
[Presentation] The novel compound 14-100 and its analogues were discovered in Cell-based Drug Discovery approach2023
- Author(s)
  Akira Yamauchi, Shuichiro Okamoto, Tominari Choshi, Naoki Katase, Nahoko Tomonobu, Rie Kinoshita, Masakiyo Sakaguchi, Masahiro Yamamura
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] S100A8/A9 とその新制御分子のバランスで成立するがん転移の機序解明2023
- Author(s)
  友信奈保子, 木下理恵, 合原勇馬, Ni Luh Gede Yoni Komalasari, Fan Jiang, 村田等, 山本健一, 山内明, 近藤英作, 豊岡伸一, 西堀正洋, 阪口政清
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] 膀胱がんの進行における S100A8/A9 に関わる分子機構の解明2023
- Author(s)
  友信奈保子、木下理恵、合原勇馬、Yoni Komalasari、二見淳一郎、山内明、近藤英作、豊岡伸一、阪口政清
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] 悪性中皮腫の治療奏効に関わるNK 細胞中のNKp46 とPD-1 の発現量変動の基礎的検討2023
- Author(s)
  西村泰光, 亀崎彩紗, 山内明, 伊藤達男
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24599
[Presentation] 膵がん進展における S100A8/A9 の役割解明と治療方法の開発2023
- Author(s)
  木下理恵、友信奈保子、山内明、二見淳一郎、豊岡伸一、阪口政清
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] 癌転移抑制を目指した細胞動態解析と創薬2023
- Author(s)
  山内明 ,町支臣成, 岡本秀一郎, 片瀬直樹, 山村真弘, 友信奈保子, 木下理恵, 阪口政清, 栗林太
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] TLR4 accelerates bladder cancer progression upon interaction with S100A8/A92023
- Author(s)
  Fan Jiang,Acosta Gonzalez Herik Rodrigo, Nahoko Tomonobu, Rie Kinoshita, Yuma Gohara, Ni Luh Gede Yoni Komalasari, Ken-ichi Yamamoto, Hitoshi Murata, Akira Yamauchi, Shinichi Toyooka, Masami Watanabe, Yasutomo Nasu, Masakiyo Sakaguchi
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] 亜鉛結合により活性化されるZEB1 転写因子の乳がん進展における意義の解明2023
- Author(s)
  山本健一, 平林大輔, 丸山顕嘉, 友信奈保子, 木下理恵, Ni Luh Gade Yoni Komalasari, 村田等, 合原勇馬, 江帆, 山内明, 栗林太, 豊岡伸一, 井上裕介, 阪口政清
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that targets the cell-surface annexin A22023
- Author(s)
  Yoni Komalasari, Nahoko Tomonobu, Rie Kinoshita, Yuma Gohara, Kenichi Yamamoto, Hitoshi Murata, Akira Yamauchi, Futoshi Kuribayashi, Yusuke Inoue, Shinichi Toyooka , Masakiyo Sakaguchi
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] NOX4 on lymphatic endothelial cells (LEC) plays an important role on the migration of pancreatic cancer cells.2020
- Author(s)
  Akira Yamauchi, Masahiro Yamamura, Naoki Katase, Nahoko Tomonobu, Rie Kinoshita, Masakiyo Sakaguchi, and Shuichiro Okamoto
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07676
[Presentation] Nox1は、消化管粘膜損傷の回復に必須の上皮細胞遊走を調節する2020
- Author(s)
  宮野佳、岡本秀一郎、山内明、梶川瑞穂、川井千景、栗林太
- Organizer
  第31回日本生体防御学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07676
[Presentation] DKK3 regulates malignant property of head and neck squamous cell carcinoma via phosphorylation of Akt.2020
- Author(s)
  Katase N, Nishimatsu S, Yamamura M, Yamauchi A
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09908
[Presentation] HSP90 inhibitor inhibit the activation of multiple kinase pathways and migration of pancreatic cancer cells2019
- Author(s)
  Yamamura M, Yamauchi A, Katase N, Yamaguchi　Y.
- Organizer
  AACR Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07676
[Presentation] Novel therapeutic approach based on S100A8/A9-mediated organ tropic cancer metastasis.2019
- Author(s)
  Kinoshita R, Tomonobu N, Yamauchi A, Shien K, Tomida S, Murata H, Futami J, Kondo E, Toyooka S, Sakaguchi M.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07676
[Presentation] ヒト末梢血由来制御性T細胞の走化性はLEMによって抑制される2019
- Author(s)
  Yamauchi　A, Kajiyama　S.
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07676
[Presentation] Melanoma cell adhesion malecule (MCAM) induces dissemination of melanoma upon S100A8/S9 binding.2019
- Author(s)
  Tomonobu N, Kinoshita R, Kondo E, Yamauchi A, Futami J, Toyooka S, Sakaguchi M.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07676
[Presentation] Anti tumor effects of 20deoxy-D-glucose encapsulated PLGA nanoparticles against hepatocellular carcinoma in term of tumor immunity2019
- Author(s)
  Sasaki K, Nishina S, Yamauchi A, Hara Y, Fukuda K, Hino K
- Organizer
  Annual Meeting of the American Association for the Study of Liver Diseases
- Data Source
  KAKENHI-PROJECT-19H03644
[Presentation] 口腔癌細胞株でのDKK3遺伝子ノックダウンは細胞の悪性度を低下させる2017
- Author(s)
  片瀬直樹、西松伸一郎、山内明、山村真弘、藤田修一、池田通
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-16K11470
[Presentation] ROS suppress the cellular chemotaxis2017
- Author(s)
  Yamauchi A, Okamoto S, Kuribayashi F.
- Organizer
  The 5th Annual Meeting of the International Cytokine and Interferon Society, ICIS 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] The Effect of ROS on the chemotaxis of Inflammatory cells2017
- Author(s)
  Yamauchi A, Okamoto S, Itadani M, Kawai C, Kuribayashi F.
- Organizer
  Con Bio 2017第41回日本分子生物学会年会・第91回日本生化学会大会合同大会
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] がん微小環境における酸化還元状態のリンパ行性転移への影響2017
- Author(s)
  山内明、山村真弘、片瀬直樹、栗林太
- Organizer
  第8回川崎医科大学学術集会
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] Heat shock protein 90 inhibitors suppress PDGFRA reactivation and other receptor tyrosine kinase activation important in drug resistant gastrointestinal stromal tumors.2017
- Author(s)
  Yamamura M,Yamauchi A, Katase N, Okawaki M, Katata Y, Kuribayashi F, Kurebayashi J, Yamaguchi Y.
- Organizer
  American Association for Cancer Research Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] Effects of 3-phenylamino-L-alanine (PAA) and 4-aminophenol (4-AP) on chemotaxis and expression of chemokine receptors in human eosinophils2016
- Author(s)
  Ayuka Tagashira, Takeaki Okamoto, Akira Yamauchi, Kosuke Nakano, Kosuke Nishi, Takuya Sugahara
- Organizer
  The 17th International Biotechnology Symposium and Exhibition (IBS 2016)
- Place of Presentation
  Melbourne Convention Centre, Melbourne（Australia）
- Year and Date
  2016-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460804
[Presentation] 肝細胞癌標的治療薬としてのDPP-4阻害剤の分子生物学的解析2016
- Author(s)
  仁科惣治, 山内　明, 佐々木恭, 小山展子, 富山恭行, 吉岡奈穂子, 原　裕一, 日野啓輔
- Organizer
  第12回広島肝臓研究センターシンポジウム
- Place of Presentation
  ホテルグランヴィア広島（広島）
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] HSP90 inhibitor inhibit the activation of multiple kinase pathways and migration of pancreatic cancer cells.2016
- Author(s)
  Masahiro Yamamura, Akira Yamauchi, Naoki Katase, Yosuke Katata, Makoto Okawaki, Akira Sawaki, Tsutomu Nohno, Yoshiyuki Yamaguchi
- Organizer
  American Association for Cancer Research, Precision Medicine Series: TARGETING THE VULNERABILITIES OF CANCER
- Place of Presentation
  JW Marriott Marquis Miami (Miami, Florida, USA)
- Year and Date
  2016-05-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] Gemcitabineは膵癌細胞の走化性に影響を与えないがDasatinibは走化性を抑制する2016
- Author(s)
  山内明, 山村真弘, 片瀬直樹, 板谷益美, 山口佳之, 栗林太
- Organizer
  第54回日本癌治療学会学術集会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-10-20
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] 肝細胞癌進展のバイオマーカーならびに治療標的としてのCD26（DPP4）の意義2016
- Author(s)
  仁科惣治, 山内明, 日野啓輔
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル（東京）
- Year and Date
  2016-04-23
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] 癌転移を惹起・増強する血清因子の探索2016
- Author(s)
  山内明, 山村真弘, 片瀬直樹, 山口佳之
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] 肝細胞癌治療標的としてのCD26(DPP4) の意義2016
- Author(s)
  仁科惣治, 山内明, 小山展子, 富山恭行, 吉岡奈穂子, 原裕一, 日野啓輔
- Organizer
  第１１３回日本内科学会総会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2016-04-16
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] HSP90 inhibitor inhibit the activation of multiple kinase pathways of pancreatic cancer cells2015
- Author(s)
  Masahiro Yamamura, Akira Yamauchi, Naoki Katase,Toshihiro Hirai
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] CD26 (DPP-4) as a molecular target for HCC treatment2015
- Author(s)
  S. Nishina, A. Yamauchi, K. Hino
- Organizer
  Japan Digestive Disease Week 2015
- Place of Presentation
  グランドプリンスホテル新高輪(東京)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] 口腔癌由来細胞におけるDKK3遺伝子発現の影響2015
- Author(s)
  片瀬直樹、寺田久美子、西松伸一郎、鈴木貴弘、松﨑秀紀、山村真弘、山内明、大槻剛巳、濃野勉
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド（神戸）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] Functional analyses of DKK3 in oral squamous cell carcinoma cell lines2015
- Author(s)
  Naoki Katase, Masahiro Yamamura, Akira Yamauchi, Takahiro Suzuki, Kumiko Terada, Shin-ichiro Nishimatsu, Tsutomu Nohno
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] 肝細胞癌標的治療薬としてのDPP-4阻害剤の分子生物学的解析2015
- Author(s)
  仁科惣治, 山内明, 小山展子, 富山恭行, 吉岡奈穂子, 原裕一, 日野啓輔
- Organizer
  第11回広島肝臓プロジェクト研究センターシンポジウム
- Place of Presentation
  ホテルグランヴィア広島(広島)
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] 肝細胞癌治療標的としてのCD26（DPP-4）の分子生物学的解析2015
- Author(s)
  仁科惣治, 山内明, 小山展子, 富山恭行, 吉岡奈穂子, 原裕一, 日野啓輔
- Organizer
  第41回日本肝臓学会西部会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] The new molecular target therapy of Hsp90 inhibition in esophageal squamous cell carcinoma2015
- Author(s)
  Masahiro Yamamura, Tsutomu Nohno, Akira Yamauchi, Naoki Katase, Makoto Okawaki, Akira Sawaki, Hideo Matsumoto, Toshihiro Hirai, Yoshiyuki Yamaguchi
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Pennsylvania Convention Center（Philadelphia, USA）
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] Suppressing pancreatic cancer metastasis by small molecular compunds2015
- Author(s)
  Yamauchi A, Yamamura M, Katase N, Itadani M, Okada N, Yamaguchi Y, Nohno T, Kuribayashi F
- Organizer
  International Conference of Cancer Immunotherapy and Macrophages 2015
- Place of Presentation
  University of Tokyo (Tokyo)
- Year and Date
  2015-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] ヒト好酸球の走化性とケモカインレセプター発現に及ぼす不純物PAAの影響2015
- Author(s)
  田頭歩佳、山内明、山内加奈子、加藤匡宏、田中守、岡本威明
- Organizer
  日本食品科学工学会
- Place of Presentation
  京都大学
- Year and Date
  2015-08-28
- Data Source
  KAKENHI-PROJECT-25460804
[Presentation] Cell-based assayによる細胞動態解析と応用2014
- Author(s)
  山内明
- Organizer
  特定非営利活動法人メディカルテクノおかやま第５８回メディカルサロン
- Place of Presentation
  岡山大学鹿田キャンパス（岡山県・岡山市）
- Year and Date
  2014-07-24
- Invited
- Data Source
  KAKENHI-PROJECT-24591473
[Presentation] ヒト末梢血由来好酸球の走化性に及ぼすPAAおよび4-APの影響2013
- Author(s)
  岡本威明、田頭歩佳、山内明、菅原卓也
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25460804
[Presentation] 好中球は走化性因子によって遊走パターンが異なる2012
- Author(s)
  山内明
- Organizer
  分子予防環境医学研究会
- Place of Presentation
  倉敷
- Year and Date
  2012-01-27
- Data Source
  KAKENHI-PROJECT-21591365
[Presentation] 細胞動態解析法により脂質メディエーター受容体の新しいシグナル伝達分子を探す。2012
- Author(s)
  山内明
- Organizer
  第3回川崎医学会学術集会
- Place of Presentation
  川崎医科大学、倉敷市
- Data Source
  KAKENHI-PROJECT-24591473
[Presentation] 好中球は走化性因子によって遊走パターンが異なる2012
- Author(s)
  山内明
- Organizer
  第11回分子予防環境医学研究会
- Place of Presentation
  倉敷市
- Year and Date
  2012-01-27
- Data Source
  KAKENHI-PROJECT-21591365
[Presentation] Robust directionality of neutrophil chemotaxis to fMLP is due to holding up the morphology2012
- Author(s)
  Akira Yamauchi
- Organizer
  日本細菌学会
- Place of Presentation
  長崎
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21591365
[Presentation] Robust directionality in neutrophil chemotaxis toward the end-target chemoattractant fMLP: an optical approach to the mechanism.2012
- Author(s)
  Akira Yamauchi
- Organizer
  International Endotoxin and Innate Immunity Society Meeting 2012 (IEIIS2012) and the 2nd Homeostatic Inflammation Symposium (HIS2012)
- Place of Presentation
  National Center of Science Building, Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-24591473
[Presentation] Robust directionality of neutrophil chemotaxis to fMLP is due to holding up the morphology2012
- Author(s)
  Akira Yamauchi
- Organizer
  第85回日本細菌学会
- Place of Presentation
  長崎市
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21591365
[Presentation] TAXIScanを用いた細胞動態解析　-炎症細胞と腫瘍細胞を中心に-2012
- Author(s)
  山内明
- Organizer
  第25回日本バイオセラピィ学会学術集会総会（招聘講演）
- Place of Presentation
  倉敷市芸文館、倉敷市
- Invited
- Data Source
  KAKENHI-PROJECT-24591473
[Presentation] 好中球の遊走パターンと遊走中の形態解析2010
- Author(s)
  山内明
- Organizer
  細胞機能可視化研究会研究集会
- Place of Presentation
  東京
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-21591365
[Presentation] TAXIScan法によるヒトリンパ球の遊走解析2010
- Author(s)
  山内明
- Organizer
  日本免疫毒性学会学術大会
- Place of Presentation
  つくば市
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21591365
[Presentation] 活性酸素を生成する食細胞NADPHオキシダーゼの発現解析2010
- Author(s)
  山内明
- Organizer
  日本生体防御学会(シンポジウム)
- Place of Presentation
  仙台
- Year and Date
  2010-07-24
- Data Source
  KAKENHI-PROJECT-21591365
[Presentation] 新規細胞動態解析装置TAXIScan技術の開発と応用2010
- Author(s)
  山内明
- Organizer
  新規細胞動態解析装置TAXIScan技術の開発と応用
- Place of Presentation
  岡山市
- Year and Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-21591365
[Presentation] Lucigenin-enhanced chemiluminescence depends on adhered granulocytes2009
- Author(s)
  栗林太, 川井千景, 山内明, 山崎剛, 大海忍
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21591365
[Presentation] 細胞動態解析法により脂質メディエーター受容体の新しいシグナル伝達分子を探す。
- Author(s)
  山内明, 栗林太
- Organizer
  第3回川崎医学会学術集会
- Place of Presentation
  川崎医科大学（倉敷市）
- Data Source
  KAKENHI-PROJECT-24591473
[Presentation] Alpha Melanocyte Stimulating Hormone enhances human melanocyte migration through CXCL12/CXCR4 axis shown by the in vitro real-time cell mobility assay.
- Author(s)
  Akira Yamauchi
- Organizer
  The 4th International Conference on Clinical & Experimental Dermatology
- Place of Presentation
  Hilton San Antonio Airport hotel (San Antonio, USA)
- Year and Date
  2014-04-14 – 2014-04-16
- Invited
- Data Source
  KAKENHI-PROJECT-24591473
[Presentation] Basic research for inhibiting pancreatic cancer metastasis: Gemcitabine vs Dasatinib.
- Author(s)
  2. Akira Yamauchi A, Masahiro Yamamura, Yoshiyuki Yamaguchi, and Futoshi Kuribayashi
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24591473
[Presentation] A tryptophan metabolite, kynurenine suppresses chemotaxis of Jurkat T-cells induced by chemokine, SDF-1alpha
- Author(s)
  Shigenobu Tone, Fumio Ohyama and Akira Yamauchi
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24591473
[Presentation] Antitumor effect of HSP90 inhibitor against esophageal cancer.
- Author(s)
  3. Masahiro Yamamura, Toshihito Hirai, Tsutomu Nohno, Naoki Katase, Akira Yamauchi, Makoto Okawaki, Hideo Matsumoto, Masafumi Nakamura, and Yoshiyuki Yamaguchi.
- Organizer
  第73回日本癌学会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-19 – 2014-09-21
- Data Source
  KAKENHI-PROJECT-24591473
[Presentation] Relationship between macrophage differentiation and the chemotactic activity toward damaged muscle cells.
- Author(s)
  Hiromi Yano, Masataka Uchida, Eri Oyanagi, Akira Yamauchi, Michael J. Kremenik
- Organizer
  The 11th International Society of Exercise and Immunology (ISEI) Symposium
- Place of Presentation
  Newcastle Town Hall, Newcastle, Australia
- Data Source
  KAKENHI-PROJECT-24591473
[Presentation] Robust directionality in neutrophil chemotaxis toward the end-target chemoattractant fMLP: an optical approach to the mechanism.
- Author(s)
  Akira Yamauchi, Shiro Kanegasaki, and Futoshi Kuribayashi
- Organizer
  International Endotoxin and Innate Immunity Society Meeting 2012 (IEIIS2012)
- Place of Presentation
  National Center of Sciences Building, Tokyo, Japa
- Data Source
  KAKENHI-PROJECT-24591473
[Presentation] Formyl peptides and chemokines augment neutrophil accumulation at the inflammation sites whereas lipid mediators support the recruitment.
- Author(s)
  Akira Yamauchi
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-24591473

1. KATASE Naoki (30566071)

# of Collaborated Projects: 6 results

# of Collaborated Products: 19 results
2. KURIBAYASHI Futoshi (60251443)

# of Collaborated Projects: 4 results

# of Collaborated Products: 22 results
3. 阪口政清 (70379840)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
4. 山村真弘 (70299204)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
5. 西松伸一郎 (20222185)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
6. 岡本秀一郎 (10529035)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
7. 藤田修一 (00181355)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
8. 西村泰光 (90360271)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. ITADANI Masumi

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. Nakamura Masafumi (30372741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OKAMOTO Takeaki (20398431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. SUGAHARA Takuya (00263963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. KATO Tadahiro (60325363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. Hino Keisuke (80228741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 仁科惣治 (70550961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 町支臣成 (10248297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 山本健一 (00711798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
18. 近藤英作 (30252951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
19. 豊岡伸一 (30397880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
20. 木下理恵 (40518297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
21. 西堀正洋 (50135943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. 友信奈保子 (80967638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
23. 村田等 (90579096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
24. YAMAUCHI Mikako

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
25. KANEGASAKI Shiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
26. TSUCHIYA Tomoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. KOBIKI Kayoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. OKANO Shinji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. WATANABE Masami

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. SAKAGUCHI Yoshihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. Kawai Chikage

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 村上孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 冨田秀太

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
34. 枝園和彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 長塚仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamauchi Akira 山内 明

YAMAUCHI Akira 山内 明

山内 明 ヤマウチ アキラ

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Why cancer cells metastasize to lymphatics from the early stage ?Principal Investigator

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Explorative research of novel factors for pancreatic cancer metastasis and proliferation based on analysis of cell dynamicsPrincipal Investigator

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Elucidating how cells migrating to chemoattractants determine the direction.Principal Investigator

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新開発の走化性測定装置を用いた好中球・好酸球の遊走制御分子の探索と新薬開発Principal Investigator

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Yamauchi Akira 山内明

YAMAUCHI Akira 山内明

山内明ヤマウチアキラ