Nagatomo Shigenori 長友重紀

… Alternative Names

NAGATOMO Shigenori 長友重紀

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Researcher Number	80373190
Other IDs
Affiliation (Current)	2025: 筑波大学, 数理物質系, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2023: 筑波大学, 数理物質系, 講師 2014: 筑波大学, 数理物質科学研究科, 講師 2014: 筑波大学, 数理物質系化学域, 講師 2013 – 2014: 筑波大学, 数理物質科学研究科(系), 講師 2012: 筑波大学, 数理物質系, 講師 … More 2007: University of Tsukuba, Graduate School of Pure and Applied Sciences, Assistant Professor 2006: 筑波大学, 大学院数理物質科学研究科, 講師 2005: 筑波大学, 大学院・数理物質科学研究科, 講師 Less
Review Section/Research Field	Principal Investigator Basic Section 32010:Fundamental physical chemistry-related / Basic Section 13040:Biophysics, chemical physics and soft matter physics-related / Biological physics/Chemical physics/Soft matter physics Except Principal Investigator Chemistry related to living body / Biophysics / Science and Engineering
Keywords	Principal Investigator ヘモグロビン / 振動分光 / βサブユニット / switch / 四次構造変化 / hinge / テラヘルツ / ゆらぎ / 協同効果 / 倒立型顕微鏡 … More / 吸収スペクトル / 亜鉛 / ラマンスペクトル / 共焦点顕微鏡 / 蛍光 / ミオグロビン / 拡散 / 細孔 / シリカゲル / ヘムタンパク質 / 機能発現 / タンパク質 / 生体分子 / 生物物理 / 協同性 / 四量体 / 三次構造変化 / αサブユニット / Fe-His結合 / heterogeneity / 非等価 / α鎖 / 低波数振動 / テラヘルツ分光 / 鉄ヒスチジン配位結合 / 酸素親和性 / 揺らぎ … More Except Principal Investigator NMR / 分子認識 / ヘム錯体 / タンパク質 / 配位結合 / 電気化学 / π-πスタッキング / 機能性核酸 / G-カルテット / 四重鎖DNA / 核酸 / Thermodynamics / Thermostability / Redox potential / Coordination bond / Electrochemistry / Metalloprotein / Heme comulex / Paramagnetic NMR / 非共有結合性相互作用 / 熱変性 / 電子移動 / 耐熱性 / 酸化還元電位 / ヘムタンパク質 / シトクロムc / タンパク質の変性 / 常磁性NMR / 熱力学 / 酸化還先電位 / へムタンパク質 / シトクロム c / 生体分子分光 / フェムト秒レーザー / 低振動 / ヘモグロビン / 振動コヒーレンス / 揺らぎ / 共鳴ラマン散乱 / 振動分光 / 生体分子 / シグナル伝達 / 蛋白質 / 生物物理 / π・πスタッキング Less

Verification of the contribution ofandchains involved in the formation of hemoglobin hinge and switch region structurePrincipal Investigator
- Principal Investigator
  
  長友重紀
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 32010:Fundamental physical chemistry-related
- Research Institution
  University of Tsukuba
Investigation of giga- and terahertz frequency of main-chain involved with function of hemoglobin confined in pore with low dielectric constantPrincipal Investigator
- Principal Investigator
  
  Nagatomo Shigenori
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 13040:Biophysics, chemical physics and soft matter physics-related
- Research Institution
  University of Tsukuba
Experimental examination for contributiions from the protein flluctuations with large amplitude and low frequencies to cooperativity of human hemoglobinPrincipal Investigator
- Principal Investigator
  
  Nagatomo Shigenori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological physics/Chemical physics/Soft matter physics
- Research Institution
  University of Tsukuba
UV resonance Raman investigation on detection of higher order structural changes of heme proteins and elucidation of functional regulation mechanism
- Principal Investigator
  
  KITAGAWA Teizo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  University of Hyogo
Vibrational coherence investigation of protein fluctuations for dynamic allostery
- Principal Investigator
  
  KUBO Minoru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biophysics
- Research Institution
  The Institute of Physical and Chemical Research
四重鎖DNAを利用したヘム錯体の空間配列制御とヘム核酸創製
- Principal Investigator
  
  山本泰彦
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  University of Tsukuba
ヘム-核酸複合体の創製と機能制御
- Principal Investigator
  
  YAMAMOTO Yasuhiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Chemistry related to living body
- Research Institution
  University of Tsukuba
Elucidation of functional properties of thermostable thermostable cytochromes c and its application to minute molecular design
- Principal Investigator
  
  YAMAMOTO Yasuhiko
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  University of Tsukuba

[Journal Article] Evolution of myoglobin diffusion mechanisms: exploring pore and surface diffusion in a single silica particle2024
- Author(s)
  Akihisa Miyagawa, Hatsuhi Kuno, Shigenori Nagatomo, Kiyoharu Nakatani
- Journal Title
  
  Analytical Sciences
  
  Volume: - Issue: 8 Pages: 1545-1551
- DOI
  10.1007/s44211-024-00575-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K03877
[Journal Article] Pore Size Dependence of Mass Transfer of Zinc Myoglobin in a Single Mesoporous Silica Particle2023
- Author(s)
  Akihisa Miyagawa, Shigenori Nagatomo, Hatsuhi Kuno, Takuto Terada, Kiyoharu Nakatani
- Journal Title
  
  Langmuir
  
  Volume: 39 Issue: 32 Pages: 11329-11336
- DOI
  10.1021/acs.langmuir.3c01017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K03877, KAKENHI-PROJECT-21K05107
[Journal Article] Heme-bound tyrosine vibrations in hemoglobin M: Resonance Raman, crystallography, and DFT calculation2022
- Author(s)
  Nagatomo Shigenori、Shoji Mitsuo、Terada Takuto、Nakatani Kiyoharu、Shigeta Yasuteru、Hirota Shun、Yanagisawa Sachiko、Kubo Minoru、Kitagawa Teizo、Nagai Masako、Ohki Mio、Park Sam-Yong、Shibayama Naoya
- Journal Title
  
  Biophysical Journal
  
  Volume: 121 Issue: 14 Pages: 2767-2780
- DOI
  10.1016/j.bpj.2022.06.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06601, KAKENHI-PROJECT-20K03877, KAKENHI-PROJECT-20H00324, KAKENHI-PLANNED-19H05784, KAKENHI-PLANNED-20H05453, KAKENHI-PUBLICLY-22H04800
[Journal Article] Structural origin of cooperativity in human hemoglobin: a view from different roles of α and β subunits in the α2β2 tetramer2022
- Author(s)
  Shigenori Nagatomo, Masako Nagai, Teizo Kitagawa
- Journal Title
  
  Biophysical Reviews
  
  Volume: 14 Issue: 2 Pages: 483-498
- DOI
  10.1007/s12551-022-00945-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K03877
[Journal Article] Kinetic Analysis of the Mass Transfer of Zinc Myoglobin in a Single Mesoporous Silica Particle by Confocal Fluorescence Microspectroscopy2021
- Author(s)
  Akihisa Miyagawa, Shigenori Nagatomo, Hiroaki Kazami, Takuto Terada, Kiyoharu Nakatani
- Journal Title
  
  Langmuir
  
  Volume: 37 Issue: 43 Pages: 12697-12704
- DOI
  10.1021/acs.langmuir.1c02127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K03877
[Journal Article] Roles of Fe-Histidine bonds in stability of hemoglobin: recognition of protein flexibility by Q Sepharose2021
- Author(s)
  Shigenori Nagatomo, Teizo Kitagawa, Masako Nagai
- Journal Title
  
  Biophysical Journal
  
  Volume: 120 Issue: 13 Pages: 1-12
- DOI
  10.1016/j.bpj.2021.05.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K03877
[Journal Article] A role of heme side-chains of human hemoglobin in its function revealed by circular dichroism and resonance Raman spectroscopy2018
- Author(s)
  M. Nagai, N. Mizusawa, T. Kitagawa, S. Nagatomo
- Journal Title
  
  Biophys. Rev. （Biophysical Reviews）
  
  Volume: 10 Issue: 2 Pages: 271-284
- DOI
  10.1007/s12551-017-0364-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K05606, KAKENHI-PROJECT-17K07732
[Journal Article] Heterogeneity between Two α Subunits of α2β2 Human Hemoglobin and O2 Binding Properties: Raman, 1H Nuclear Magnetic Resonance, and Terahertz Spectra2017
- Author(s)
  Shigenori Nagatomo, Kazuya Saito, Kohji Yamamoto, Takashi Ogura, Teizo Kitagawa, and Masako Nagai
- Journal Title
  
  Biochemistry
  
  Volume: 56 Issue: 46 Pages: 6125-6136
- DOI
  10.1021/acs.biochem.7b00733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K05649, KAKENHI-PROJECT-17K05606
[Journal Article] Involvement of propionate side chians of the hee in circular dichroism of myoglobin: experimental and theoretical analyses2015
- Author(s)
  M. Nagai, C. Kobayashi, Y. Nagai, K. Imai, N. Mizusawa, H. Sakurai, S. Neya, M. Kayanuma, M. Shoji and S. Nagatomo
- Journal Title
  
  J. Phys. Chem. B
  
  Volume: 119 Pages: 1275-1287
- Data Source
  KAKENHI-PROJECT-24350086
[Journal Article] Recentant nematic phase in 4-alkyl-4'-cyanobiphenyl(nCB) binary mixtures2014
- Author(s)
  S. Fujimura, Y. Yamamura, M. Hishida, S. Nagatomo, and K. Saito
- Journal Title
  
  Liquid Crystals
  
  Volume: 41 Pages: 927-932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24350086
[Journal Article] Near-UV Circular dichroism and UV resonance Raman spectra of tryptophan residues as a structural marker of proteins.2013
- Author(s)
  Shigenori Nagatomo, Masako Nagai, Takashi Ogura, and Teizo Kitagawa
- Journal Title
  
  J. Physical Chemistry　B
  
  Volume: 117 Issue: 32 Pages: 9343-9363
- DOI
  10.1021/jp404685x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24350086
[Journal Article] Effective Pumping Proton Collection Facilitated by a Copper Site (CuB) of Bovine Heart Cytochrome c Oxidase, Revealed by a Newly Developed Time-resolved Infrared System2013
- Author(s)
  Minoru Kubo, Satoru Nakashima, Satoru Yamaguchi, Takashi Ogura, Masao Mochizuki, Jiyoung Kang, Masaru Tateno, Kyoko Shinzawa-Itoh, Koji Kato and Shinya Yoshikawa
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 42 Pages: 30259-30269
- DOI
  10.1074/jbc.m113.473983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23550022, KAKENHI-PROJECT-23685040, KAKENHI-PROJECT-24350086, KAKENHI-PUBLICLY-25109540
[Journal Article] Identification of Hydrogen-Bonded Oligomers in Associating Liquid by 'H NMR : 1-Phenyl-1-cyclohexanol2013
- Author(s)
  Shigenori Nagatomo, Megumi Nobuhira, Yasuhisa Yamamura, Masato Sumita, and Kazuya Saito
- Journal Title
  
  Bull. Chem. Soc. Jpn.
  
  Volume: (印刷中) Issue: 5 Pages: 569-576
- DOI
  10.1246/bcsj.20120322
- NAID
  10031167848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24350086
[Journal Article] Near-UV circular dichroism and UV resonance Raman spectra of individual trytophan residues in human hemoglobin and their changes upon the quaternary structure transition2012
- Author(s)
  Masako Nagai, Shigenori Nagatomo, Yukifumi Nagai, Kenichi Ohkubo, Kiyohiro Imai, and Teizo Kitagawa
- Journal Title
  
  Biochemistry
  
  Volume: 51 Issue: 30 Pages: 5932-5941
- DOI
  10.1021/bi300347x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24350086, KAKENHI-PUBLICLY-25109540
[Journal Article] Effect of reversed heme orientagion on circular dichroism and cooperative oxygen binding of human adult hemoglobin2008
- Author(s)
  Nagai, Y. Nagai, Y. Aki, K. Imai, S. Nagatomo, and Y. Yamamoto
- Journal Title
  
  Biochemistry 47
  
  Pages: 517-525
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Journal Article] Dynamics and thermodynamics of dimerization of parallel G-quadriplexed DNA through p-p stacking interaction2005
- Author(s)
  Y. Kato, T. Ohyama, S. Nagatomo, H. Mita, and Y. Yamamoto
- Journal Title
  
  NucleicAcids Symp. Ser 49
  
  Pages: 247-248
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Journal Article] Structural and functional charcterization of novel G-quadruplexed DNA-heme coordination complex2005
- Author(s)
  T. Ohyama, Y. Kato, H. Mita, S. Nagatomo, and Y. Yamamoto
- Journal Title
  
  NucleicAcids Symp. Ser 49
  
  Pages: 245-246
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Journal Article] Characterization of non-native heme coordination structures emerging upon guanidine hydrochloric acid-induced unfolding of Pseudomonas aeruginosa ferricytochrome c5512005
- Author(s)
  H. Tai, S. Nagatomo, H. Mita, Y. Sambongi, and Y. Yamamoto
- Journal Title
  
  Bull. Chem. Soc. Jpn 78
  
  Pages: 2019-2025
- NAID
  130004058601
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] ヘモグロビンM IwateとM BostonのFe-O伸縮振動の理論計算の改良およびヘモグロビンAとの構造の比較2023
- Author(s)
  長友重紀，寺田拓人，庄司光男，重田育照，中谷清治，廣田俊，柳澤幸子，久保稔，北川禎三，長井雅子，大木規央，朴三用，柴山修哉
- Organizer
  第49回生体分子科学討論会
- Data Source
  KAKENHI-PROJECT-23K04660
[Presentation] Crystallographic structures of four kinds of Hemoglobin M which has Fe-Tyr coordination bond2023
- Author(s)
  Shigenori Nagatomo, Ayana Sato-Tomita, Yumi Semba, Akihisa Miyagawa, Kiyoharu Nakatani, Mio Ohki, Kenji Mizutani, Sam-Yong Park, Naoya Shibayama
- Organizer
  The 61th Annual Meeting of the Biophysical Society of Japan
- Data Source
  KAKENHI-PROJECT-23K04660
[Presentation] ヘモグロビンM IwateとM Bostonにおけるヘム-チロシン結合の振動分光，結晶構造，理論計算による解析2021
- Author(s)
  長友重紀，寺田拓人，庄司光男，重田育照，中谷清治，廣田俊，北川禎三，長井雅子，大木規央, 朴三用, 柴山修哉
- Organizer
  第47回生体分子科学討論会
- Data Source
  KAKENHI-PROJECT-20K03877
[Presentation] 細孔内に取りこまれたヒト成人ヘモグロビンの機能発現におけるGHz, THz領域の主鎖のゆらぎの実験的検証2021
- Author(s)
  長友重紀
- Organizer
  2020年度福井大学遠赤外領域開発研究センター共同研究成果報告会
- Data Source
  KAKENHI-PROJECT-20K03877
[Presentation] 単一メソ多孔性シリカゲル微粒子/水系における亜鉛ミオグロビンの細孔内物質移動過程の細孔径依存性2020
- Author(s)
  寺田拓人，風見裕明，宮川晃尚，長友重紀，中谷清治
- Organizer
  第39回溶媒抽出討論会
- Data Source
  KAKENHI-PROJECT-20K03877
[Presentation] Separation of tetramer-dimer mixtures mutant hemoglobin by structural flexibility2020
- Author(s)
  Shigenori Nagatomo, Teizo Kitagawa, Masako Nagai
- Organizer
  The 58th Annual Meeting of the Biophysical Society of Japan
- Data Source
  KAKENHI-PROJECT-20K03877
[Presentation] チロシン配位の天然の変異ヘモグロビンで観測される帰属未定の振動バンドの挙動と性質2019
- Author(s)
  長友重紀，寺田拓人，庄司光男，重田育照，中谷清治，廣田俊，長井雅子，北川禎三
- Organizer
  第46回生体分子科学討論会
- Data Source
  KAKENHI-PROJECT-17K05606
[Presentation] ヒト成人ヘモグロビンの酸素親和性制御に関連したGHz, THz領域振動の研究2019
- Author(s)
  Shigenori Nagatomo, Kohji Yamamoto, Masako Nagai, Teizo Kitagawa
- Organizer
  日本生物物理学会第57回年会
- Data Source
  KAKENHI-PROJECT-17K05606
[Presentation] Different roles between α and β subunits in α2β2 tetramer for cooperative O2 binding of hemoglobin2018
- Author(s)
  Shigenori Nagatomo, Takashi Ogura, Teizo Kitagawa, Masako Nagai
- Organizer
  Tenth International Conference on Porphyrins & Phthalocyanines (ICPP-10)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K05606
[Presentation] ヒト成人ヘモグロビンの四量体構造の安定性に対するβサブユニットのFe-His結合の寄与2018
- Author(s)
  長友重紀，長井雅子，北川禎三
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17K05606
[Presentation] ヒト成人ヘモグロビンのα、βそれぞれのサブユニットのFe-His結合と酸素親和性との関係2017
- Author(s)
  長友重紀，奥村美紀，齋藤一弥，小倉尚志，北川禎三，長井雅子
- Organizer
  第44回生体分子科学討論会
- Data Source
  KAKENHI-PROJECT-17K05606
[Presentation] ヘモグロビンの酸素親和性制御に関係する大振幅ヘリックス揺らぎの実験的検証：テラヘルツ(THz)分光による研究2017
- Author(s)
  長友重紀，山本晃司，長井雅子，北川禎三
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17K05606
[Presentation] 生体高分子の機能制御におけるゆらぎの役割2013
- Author(s)
  長友重紀
- Organizer
  つくばソフトマター研究会2013
- Place of Presentation
  筑波大学（茨城県）
- Invited
- Data Source
  KAKENHI-PROJECT-24350086
[Presentation] ヘモグロビンの機能制御における四次構造変化、α鎖，β鎖の役割：共鳴ラマン分光による研究2013
- Author(s)
  長友重紀
- Organizer
  第26回生物無機化学夏季セミナー（生物無機化学研究会）
- Place of Presentation
  茨城県、阿字ケ浦クラブ
- Invited
- Data Source
  KAKENHI-PROJECT-24350086
[Presentation] Thermodynamic Study of Cyclic Oligomers via Hydrogen Bonds in Organic Liquids2013
- Author(s)
  higenori Nagatomo, Yasuhisa Yamamura, Kazuya Saito
- Organizer
  The Fifth International Symposium on the New Frontiers of Thermal Studies of Materials.
- Place of Presentation
  Yokohama Media and Communications Center（神奈川県）
- Data Source
  KAKENHI-PROJECT-24350086
[Presentation] タンパク質中のトリプトファン残基の近紫外円二色性と紫外共鳴ラマンスペクトルの特性2013
- Author(s)
  higenori Nagatomo, Masako Nagai, Takashi Ogura, and Teizo Kitagawa
- Organizer
  第51回日本生物物理学会年会
- Place of Presentation
  京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-24350086
[Presentation] Relation among Fe-His bond, fluctuations of helices and oxygen affinity of hemoglobin in T-state and R-state2012
- Author(s)
  Shigenori Nagatomo, Yukiko Ozeki, Yasuhisa Yamamura, and Kazuya Saito
- Organizer
  Molecular Science of Fluctuations toward Biological Functions, 6th International Symposium
- Place of Presentation
  Kyoto University (Kyoto)
- Data Source
  KAKENHI-PROJECT-24350086
[Presentation] ヒト成人ヘモグロビンへのベザフィブラートの結合による酸素親和性低下に関連した三次構造変化の解明2012
- Author(s)
  長友重紀,濱田洋実,吉川裕之,斎藤一弥
- Organizer
  第39回生体分子科学討論会
- Place of Presentation
  東北大学片平さくらホール(宮城県)
- Data Source
  KAKENHI-PROJECT-24350086
[Presentation] Substitution effects of Gly for the proximal His of α subunits on the structure and oxygen binding function of human hemoglobin2012
- Author(s)
  Yayoi Aki, Yukifumi Nagai, Kiyohiro Imai, Shigenori Nagatomo, Takashi Ogura, Teizo Kitagawa, and Masako Nagai
- Organizer
  The 50th Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  Nagoya University (Aichi)
- Data Source
  KAKENHI-PROJECT-24350086
[Presentation] ヒトヘモグロビンの酸素結合機能における近位ヒスチジンの役割2012
- Author(s)
  丸山夏未,安芸弥生,長井幸史,今井清博,長友重紀,小倉尚志,北川禎三,長井雅子
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡(福岡県)
- Data Source
  KAKENHI-PROJECT-24350086
[Presentation] Essence in oxygen affinity regulation of human adult hemoglobin : Change of Fe-His bond length by quaternary or tertiary structure change2012
- Author(s)
  Shigenori Nagatomo, Yasuhisa Yamamura, and Kazuya Saito
- Organizer
  The 50th Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  Nagoya University (Aichi)
- Data Source
  KAKENHI-PROJECT-24350086
[Presentation] トリプトファンの近紫外円二色性及び紫外共鳴ラマンに基づくヘモグロビンの四次構造変化の解明2012
- Author(s)
  長井雅子,長友重紀,長井幸史,大久保賢一,今井清博,北川禎三
- Organizer
  第39回生体分子科学討論会
- Place of Presentation
  東北大学片平さくらホール(宮城県)
- Data Source
  KAKENHI-PROJECT-24350086
[Presentation] Characterization of electron transfer from cytochrome cto blue copper proteins2009
- Author(s)
  S. J. Takayama, H. Tai, S. Mikami, K. Irie, M. Kage, S. Kawano, S, Nagatomo, T. Kawahara, N. Funasaki, A. Takabe, S. Hirota, and Y. Yamamoto
- Organizer
  Global COE in Chemistry, Nagoya Special Symposium
- Place of Presentation
  Nagoya Univ
- Year and Date
  2009-03-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Structural and functional properties of heme-DNA complex2008
- Author(s)
  Y. Yamamoto, S. Kawano, and S, Nagatomo
- Organizer
  5th Workshop on Chemistry of Biological Processes Created by Water and Biomolecules
- Place of Presentation
  Nara City
- Year and Date
  2008-01-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Regulation of redox potential of PP aeruginosa cytochrome c through alteration of electrostatic environment around heme 17-propionic acid2008
- Author(s)
  S. Mikami, K. Irie, S. J. Takayama, H. Tai, M. Kage, S. Kawano, S, Nagatomo, and Y. Yamamoto
- Organizer
  Global COE in Chemistry, Nagoya Special Symposium
- Place of Presentation
  Nagoya Univ
- Year and Date
  2008-03-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Electrostatic interaction between the terminal helices of cytochrome c and its contribution to the protein stability2008
- Author(s)
  M. Kage, K. Brie, H. Tai, S. Mikami, S. Kawano, S. Nagatomo, and Y. Yamamoto
- Organizer
  88th Annual Meeting of the Chemical Society of Japan
- Place of Presentation
  Rikkyo Univ
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Stability of the coordination bond between heme and Nterminal amino group of denatured cytochrome c2008
- Author(s)
  H. Tai, T. munegumi, S. Nagatomo, S. Kawano, and Y. Yamamoto
- Organizer
  88th Annual Meeting of the Chemical Society of Japan
- Place of Presentation
  Rikkyo Univ
- Year and Date
  2008-03-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] ^19F NMR characterization of Fe-His coordination bond of hemoprotein bearing a C_2 symmetric fluorinated heme2008
- Author(s)
  K. Mizuseki, T. Miyazaki, T. Shibata, H. Furuichi, S, Nagatomo, S. Kawano, Y. Yamamoto and A. Suzuki
- Organizer
  88th Annual Meeting of the Chemical Society of Japan
- Place of Presentation
  Rikkyo Univ
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] In-cell NMR characterization of functional properties of hemoglobin tetramer2008
- Author(s)
  A. Sato, S, Nagatomo, S. Kawano, and Y. Yamamoto
- Organizer
  88th Annual Meeting of the Chemical Society of Japan
- Place of Presentation
  Rikkyo Univ
- Year and Date
  2008-03-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] The effects of conformational change of a loop region adjacent to heme on the redox function of cytochrome c2008
- Author(s)
  S. Mikami, T. Udagawa, K. Irie, S. J. Takayama, H. Tai, S. Kawano, S. Nagatomo, and Y. Yamamoto
- Organizer
  88th Annual Meeting of the Chemical Society of Japan
- Place of Presentation
  Rikkyo Univ
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Electron transfer from cytochrome c to blue copper Proteins2008
- Author(s)
  K. Irie, S. J. Takayama, H. Tai, S. Mikami, M. Kage, S. Kawano, S, Nagatomo, T. Kawahara, N. Funasaki, A. Takabe, S. Hirota, and Y. Yamamoto
- Organizer
  First International Symposium on Interdisciplinary Materials Science
- Place of Presentation
  Tsukuba City
- Year and Date
  2008-03-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Characterization of internal mobility of heme active site in Hydrogenobacter thermophilus cytochrome c5522008
- Author(s)
  K. Iirie, H. Hemmi, S. Kawano, S. J. Takayama, E. Iwao, S. Nagatomo, and Y. Yamamoto
- Organizer
  88th Annual Meeting of the Chemical Society of Japan
- Place of Presentation
  Rikkyo Univ
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Molecular design of heme-DNA complex using the scaffold of G-quadruplex DNA dimer2008
- Author(s)
  N. Sakuma, H. Ujiie, S. Kawano, H. Hemmi, S. Nagatomo, and Y. Yamamoto
- Organizer
  88th Annual Meeting of the Chemical Society of Japan
- Place of Presentation
  Rikkyo Univ
- Year and Date
  2008-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] ^19F NMR study of tetrameric hemoglobin2008
- Author(s)
  Y S. Nagao, S. Nagatomo, Y. Yamamoto, and A. Suzuki
- Organizer
  21st Symposium on Biofunctional Chemistry
- Place of Presentation
  Kyouto Univ
- Year and Date
  2008-09-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Role of heme 17propionic acid in the regulation of redox potential of Psedomonas aeruginosa cytochrome c5512008
- Author(s)
  S. Mikami, K. Irie, S. J. Takayama, H. Tai, M. Kage, S. Kawano, S, Nagatomo, and Y. Yamamoto
- Organizer
  First International Symposium on Interdisciplinary Materials Science
- Place of Presentation
  Tsukuba City
- Year and Date
  2008-03-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Effects of structural change in hydrophobic core of Hydrogenobacter thermophilus cytochrome cts2 in its redox properties and thermostability2007
- Author(s)
  K. Irie, Y. Takahashi, S. J. Takayama, S. Mikami, M. Kage, S. Kawano, S, Nagatomo, Y. Yamamoto
- Organizer
  57th Annual Meeting of the Coordination Chemistry of Japan
- Place of Presentation
  Nagoya Inst. Tech
- Year and Date
  2007-09-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] ^19F NMR study of the acid-alkaline transition of metmyoglobin and methemoglobin bearing a fluorinated heme2007
- Author(s)
  T. Shibata, K. Mizuseki, S. Nagao, Y. Hirai, S. Kawano, S, Nagatomo, Y. Yamamoto, and A. Suzuki
- Organizer
  16th Triennial Conference for the International Society of Magnetic Resonance
- Place of Presentation
  Kenting, Taiwan
- Year and Date
  2007-10-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Paramagnetic NMR characterization of non-native heme coordination structure emerging upon guanidine hydrochloric acid-induced unfolding of cytochrome c2007
- Author(s)
  H. Tai, S. J. Takayama, S. Kawano, S, Nagatomo, and Y. Yamamoto
- Organizer
  46th Annual Meeting of the NMR Society of Japan
- Place of Presentation
  Sapporo City
- Year and Date
  2007-09-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Field dependence study of ^19F NMR signal of hemoprotein reconstituted with a ring fluorinated heme2007
- Author(s)
  T. Miyazaki, S. Nagao, Y. Hirai, S, Nagatomo, Y. Yamamoto, and A. Suzuki
- Organizer
  16th Triennial Conference for the International Society of Magnetic Resonance
- Place of Presentation
  Kenting, Taiwan
- Year and Date
  2007-10-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Analysis of the acid-alkaline transition in human adult and fetal tetrameric hemoglobins and their isolated chains2007
- Author(s)
  T. Shibata, S. Nagao, S. Kawano, H. Mita, S. Nagatomo, S. Hamada, H. Yoshikawa, H. Tsunoda, and Y. Yamamoto
- Organizer
  87th Annual Meeting of the Chemical Society of Japan
- Place of Presentation
  Kansai Univ
- Year and Date
  2007-03-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] ^19F NMR Characterization of Hemoproteins Reconstituted with Fluorinated Hemes2007
- Author(s)
  Y. Yamamoto, S. Nagao, K. Mizuseki, S. Kawano, S, Nagatomo, and A. Suzuki
- Organizer
  16th Triennial Conference for the International Society of Magnetic Resonance
- Place of Presentation
  Kenting, Taiwan
- Year and Date
  2007-10-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Regulation of redox potential of cytochrome cthrough alteration of electrostatic environment around heme 17-propionic acid2007
- Author(s)
  S. Mikami, S. J. Takayama, H. Tai, K. Irie, M. Kage, S. Kawano, S, Nagatomo, and Y. Yamamoto
- Organizer
  34th Meeting on Biomolecular Science
- Place of Presentation
  Tohoku Univ
- Year and Date
  2007-06-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Enhancement of thermostability of H thermophilus cytochrome aa2 through stabilization of hydrophobic core2006
- Author(s)
  S. J. Takayama, H. Sasaki, Y. Takahashi, S. Mikami, Y. Sambongi, S. Nagatomo, H. Mita, and Y. Yamamoto
- Organizer
  4th International Conference on Porphyrins and Phthalocyanines
- Place of Presentation
  Rome, Italy
- Year and Date
  2006-07-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Characterization of internal dynamics of thermophile Hydrogenobacter thermophilus cytochrome c Using High Pressure NMR2006
- Author(s)
  S. J. Takayama, Y. Takahashi, S. Mikami, S. Nagatomo, H. Mita, Y. Yamamoto, Y. Sambongi, R. Kitahara, S. Yokoyama, and K. Akasaka
- Organizer
  XXIIND International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  Gottingen, German
- Year and Date
  2006-08-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] NMR study of effect of phosphate ion on the acid-alkaline transition in human adult and fetal tetrameric ferrihemoglobins2006
- Author(s)
  S. Nagatomo, S. Nagao, H. Mita, S. Hamada, H. Tsunoda, H. Yoshikawa, and Y. Yamamoto
- Organizer
  06-01NMR Workshop
- Place of Presentation
  Univ. of Tsukuba
- Year and Date
  2006-05-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Dimerization of parallel G-quadruplex DNAs formed from d(TTAG_3)2006
- Author(s)
  H. Mita, T. Ohyama, Y. Kato, S. Nagatomo, and Y. Yamamoto
- Organizer
  06-01NMR Workshop
- Place of Presentation
  Univ. of Tsukuba
- Year and Date
  2006-05-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Non-native heme coordination structure emerging upon guanidine hydrochloric acid-induced unfolding of Pseudomonas aeruginosa ferricytochrome c5512006
- Author(s)
  H. Tai, S. Nagatomo, H. Mita, Y. Sambongi, and Y. Yamamoto
- Organizer
  4th International Conference on Porphyrins and Phthalocyanines
- Place of Presentation
  Rome, Italy
- Year and Date
  2006-07-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] ^19F NMR study of b-type hemoproteins bearing a fluorinated heme2006
- Author(s)
  S. Nagao, S, Nagatomo, H. Mita, Y. Yamamoto, and A. Suzuki
- Organizer
  06-01NMR Workshop
- Place of Presentation
  Univ. of Tsukuba
- Year and Date
  2006-05-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Structural characterization of unfolding intermediates emerging upon guanidine hydrochloric acid-induced denaturation of Thermophile Hydrogenobacter thermophilus Cytochrome c5522006
- Author(s)
  H. Tai, T. Udagawa, S. J. Takayama, S. Mikami, Y. Sambongi, S. Nagatomo, H. Mita, and Y. Yamamoto
- Organizer
  06-01NMR Workshop
- Place of Presentation
  Univ. of Tsukuba
- Year and Date
  2006-05-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] ^19F NAM study of hemoproteins bearing a fluorinated heme2006
- Author(s)
  S. Nagao, S, Nagatomo, H. Mita, Y. Yamamoto, and A. Suzuki
- Organizer
  4th International Conference on Porphyrins and Phthalocyanines
- Place of Presentation
  Rome, Italy
- Year and Date
  2006-07-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17350081
[Presentation] Function and structure of mutant hemoglobins with proximal histidine replaced by glycine in either a or b subunits
- Author(s)
  S. Nagatomo, Y. Nagai, Y. Aki, H. Sakurai, N. Maruyama, K. Imai, N. Mizusawa, T. Ogura, T. Kitagawa and m. Nagai
- Organizer
  日本生物物理学会第５２回年会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24350086

1. YAMAMOTO Yasuhiko (00191453)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
2. 三田肇 (00282301)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
3. KAWANO Shin (90431676)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
4. KITAGAWA Teizo (40029955)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
5. OGURA Takashi (70183770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. KUBO Minoru (90392878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 中谷清治 (00250415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. 庄司光男 (00593550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 中島聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 柴山修哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 山本晃司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagatomo Shigenori 長友 重紀

NAGATOMO Shigenori 長友 重紀

Research Projects

Research Products

Co-Researchers

Verification of the contribution ofandchains involved in the formation of hemoglobin hinge and switch region structurePrincipal Investigator

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Investigation of giga- and terahertz frequency of main-chain involved with function of hemoglobin confined in pore with low dielectric constantPrincipal Investigator

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Experimental examination for contributiions from the protein flluctuations with large amplitude and low frequencies to cooperativity of human hemoglobinPrincipal Investigator

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UV resonance Raman investigation on detection of higher order structural changes of heme proteins and elucidation of functional regulation mechanism

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Vibrational coherence investigation of protein fluctuations for dynamic allostery

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四重鎖DNAを利用したヘム錯体の空間配列制御とヘム核酸創製

Principal Investigator

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ヘム-核酸複合体の創製と機能制御

Principal Investigator

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Elucidation of functional properties of thermostable thermostable cytochromes c and its application to minute molecular design

Principal Investigator

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[Journal Article] Evolution of myoglobin diffusion mechanisms: exploring pore and surface diffusion in a single silica particle2024

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Data Source

[Journal Article] Pore Size Dependence of Mass Transfer of Zinc Myoglobin in a Single Mesoporous Silica Particle2023

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[Journal Article] Heme-bound tyrosine vibrations in hemoglobin M: Resonance Raman, crystallography, and DFT calculation2022

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[Journal Article] Structural origin of cooperativity in human hemoglobin: a view from different roles of α and β subunits in the α2β2 tetramer2022

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[Journal Article] Kinetic Analysis of the Mass Transfer of Zinc Myoglobin in a Single Mesoporous Silica Particle by Confocal Fluorescence Microspectroscopy2021

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[Journal Article] Roles of Fe-Histidine bonds in stability of hemoglobin: recognition of protein flexibility by Q Sepharose2021

Author(s)

Nagatomo Shigenori 長友重紀

NAGATOMO Shigenori 長友重紀