HARII Norikazu 針井則一

Researcher Number	80377522
Affiliation (Current)	2022: 山梨大学, 大学院総合研究部, 特任准教授
Affiliation (based on the past Project Information) *help	2018 – 2021: 山梨大学, 大学院総合研究部, 特任准教授 2017: 山梨大学, 大学院総合研究部, 准教授 2014 – 2016: 山梨大学, 総合研究部, 准教授 2012 – 2013: 山梨大学, 医学工学総合研究部, 助教 2010 – 2012: 山梨大学, 大学院・医学工学総合研究部, 助教 2006: University of Yamanashi, University of Yamanashi Hospital, Senior Resident, 医学部附属病院, シニアレジデント 2005: 山梨大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Emergency medicine / Basic Section 55060:Emergency medicine-related Except Principal Investigator Emergency medicine / Metabolomics
Keywords	Principal Investigator 急性呼吸窮迫症候群 / 完全液体呼吸 / ARDS / 完全液体換気 / 血液浄化療法 / 敗血症性多臓器不全 / ラットエンドトキシンショックモデル / 急性血液浄化療法 / 敗血症 / 集中治療医学 … More Except Principal Investigator 救命 / 解析・評価 / 可視化 / ソフトウェア開発 / 電子デバイス・機器 / 栄養学 / 生体機能利用 / 情報工学 / 膵β細胞再生 / 分化誘導 / 膵特異的遺伝子 / 分子生物学 / pancreatic β-cell regeneration / differentiation / pancreas specific gene / molecular biology / 腸蠕動運動 / 経腸栄養 / 重症患者 / 救急医学 / 災害医学 / 集中治療 / 血液浄化 / 人工臓器 / 人工腎臓 Less

ARDSモデルラットにおける短時間液体呼吸と新規薬物伝達システムの治療効果の検証Principal Investigator
- Principal Investigator
  
  針井則一
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  University of Yamanashi
Total liquid ventilation with oxygen micro/nano bubble dispersion ameliorates lipopolysaccharide-induced acute respiratory distress syndrome in rats.Principal Investigator
- Principal Investigator
  
  HARII Norikazu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  University of Yamanashi
Clinical application of the bowel sound monitoring system by real time bowel sound analysis in critical patients
- Principal Investigator
  
  GOTO Junko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  University of Yamanashi
The possibility of therapeutic application of temporary total liquid ventilation in rat acute respiratory distress syndrome model.Principal Investigator
- Principal Investigator
  
  HARII Norikazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  University of Yamanashi
Challenge to a portable blood purification system
- Principal Investigator
  
  MATSUDA Kenichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Emergency medicine
- Research Institution
  University of Yamanashi
Examination of a different membranes on cytokine adsorption on circulating cytokine and search of a biomarker as a prognosticator in a sepsis rat continuous heamodiafiltration modelPrincipal Investigator
- Principal Investigator
  
  HARII Norikazu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  University of Yamanashi
Development of an intestines peristalsis monitoring system by thecontinuous bowel-sounds analysis in the critically ill patients
- Principal Investigator
  
  MATSUDA Kenichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  University of Yamanashi
Identification of genes that are involved in differentiation of pancreatic ductal cells to pancreatic β-cells.
- Principal Investigator
  
  AIDA Kaoru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  University of Yamanashi

All 2020 2019 2017 2016 2015 2013 2012

All Journal Article Presentation Patent

[Journal Article] Total alveolar lavage with oxygen fine bubble dispersion directly improves lipopolysaccharide-induced acute respiratory distress syndrome of rats2020
- Author(s)
  Kakiuchi Kenta、Miyasaka Takehiro、Takeoka Shinji、Matsuda Kenichi、Harii Norikazu
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Pages: 1-10
- DOI
  10.1038/s41598-020-73768-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22506, KAKENHI-PROJECT-18K08913
[Journal Article] 重症患者における連続陽音解析システムの臨床応用2016
- Author(s)
  後藤順子，松田兼一，針井則一，森口武史，原田大希，菅原久徳，高三野淳一，吉野匠，阪田治松田兼一，針井則一，森口武史，原田大希，菅原久徳，高三野淳一，吉野匠，阪田治
- Journal Title
  
  日本静脈経腸栄養学会雑誌
  
  Volume: 31 Pages: 807-810
- Data Source
  KAKENHI-PROJECT-15K10971
[Journal Article] 重症患者における連続腸音解析システムの臨床応用2016
- Author(s)
  後藤順子，松田兼一，針井則一，森口武史，原田大希，菅原久徳，高三野淳一，吉野　匠，阪田　治
- Journal Title
  
  日本静脈経腸栄養学会雑誌
  
  Volume: 31 Pages: 1-4
- NAID
  130005158199
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10971
[Journal Article] 急性腎心症候群2015
- Author(s)
  菅原久徳，松田兼一，針井則一，森口武史，後藤順子，柳沢政彦，原田大希
- Journal Title
  
  心臓
  
  Volume: 47 Pages: 546-550
- Data Source
  KAKENHI-PROJECT-15K10971
[Journal Article] 重症急性膵炎に対する血液浄化療法2015
- Author(s)
  柳沢政彦，松田兼一，針井則一，森口武史，後藤順子，原田大希，菅原久徳，高三野淳一，吉野　匠，
- Journal Title
  
  腎臓内科・泌尿器科
  
  Volume: 1 Pages: 556-563
- Data Source
  KAKENHI-PROJECT-15K10971
[Journal Article] 細径化したファイバを用いたヘモフィルタの開発2015
- Author(s)
  栗原佳孝, 小久保謙一, 小林こず恵, 後田洋輔, 塚尾浩, 柳沢政彦, 後藤順子, 針井則一, 森口武史, 松田兼一, 小林弘祐
- Journal Title
  
  医工学治療
  
  Volume: 27 Pages: 44-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05005
[Patent] 蠕動音検出装置、蠕動音検出方法、プログラム、および記録媒体2012
- Inventor(s)
  松岡憲弘,松田兼一,阪田治,針井則一
- Industrial Property Rights Holder
  シャープ株式会社、山梨大学
- Industrial Property Number
  2012-013464
- Filing Date
  2012-01-25
- Data Source
  KAKENHI-PROJECT-22592011
[Patent] 蠕動音検出装置、蠕動音検出方法、プログラム、および記録媒体2012
- Inventor(s)
  松岡憲弘, 松田兼一, 阪田治, 針井則一
- Industrial Property Rights Holder
  シャープ株式会社、山梨大学
- Industrial Property Number
  2012-013464
- Filing Date
  2012-01-25
- Data Source
  KAKENHI-PROJECT-22592011
[Presentation] 酸素ファインバブル分散液を用いた完全液体換気技術の開発2020
- Author(s)
  垣内健太，針井則一，宮坂武寛，武岡真司
- Organizer
  第24回酸素ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-18K08913
[Presentation] 酸素マイクロ・ナノバブル分散酸素富化液を用いた完全液体換気の確立2019
- Author(s)
  垣内健太，松田兼一，針井則一，宮坂武寛，武岡真司
- Organizer
  第2回　稲門医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08913
[Presentation] Total liquid ventilation with oxygen fine bubbles for acute lung injury,2019
- Author(s)
  Kenta Kakiuchi, Norikazu Harii, Takehiro Miyasaka, Shinji Takeoka, Kenichi Matsuda
- Organizer
  The 17th International Symposium on Blood Substitutes and Oxygen Therapeutics, Nara, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08913
[Presentation] Total Liquid Ventilation with Oxygen Fine Bubble Dispersion Prevents from Acute Lung Injury in Rats2019
- Author(s)
  Kenta Kakiuchi, Norikazu Harii, Takehiro Miyasaka, Shinji Takeoka, Kenichi Matsuda
- Organizer
  The 8th Meeting of the International Federation for Artificial Organs, Osaka, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08913
[Presentation] TOTAL LIQUID VENTILATION WITH OXYGEN MICRO/NANO BUBBLE DISPERSED SALINE PREVENTS FROM LIPOPOLYSACCHARIDE-INDUCED ACUTE LUNG INJURY IN RATS2019
- Author(s)
  Kenta Kakiuchi, Shinji Takeoka, Norikazu Harii, Takehiro Miyasaka, Kenichi Matsuda
- Organizer
  The 46th European Society for Artificial Organs, Germany
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08913
[Presentation] 論文賞受賞を振り返って2017
- Author(s)
  後藤順子，松田兼一，針井則一，森口武史，阪田治
- Organizer
  第55回人工臓器学会大会
- Data Source
  KAKENHI-PROJECT-15K10971
[Presentation] Application of micro/nano bubble dispersion for total liquid ventilation2017
- Author(s)
  Hiroto Sato, Takehiro Miyasaka, Norikazu Harii, Kenichi Matsuda, Shinji Takeoka
- Organizer
  44th Annual Congress of the European Society for Artificial Organs (Sep. 2017, VIENNA, Austria)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10972
[Presentation] 酸素マイクロ・ナノバブル分散液を用いた完全液体換気から気体換気への復帰2017
- Author(s)
  佐藤啓斗, 針井則一, 宮坂武寛, 松田兼一, 武岡真司
- Organizer
  第24回日本血液代替物学会（東京）
- Data Source
  KAKENHI-PROJECT-15K10972
[Presentation] 後腹膜悪性腫瘍に伴い腹部大動脈の血栓閉塞を来たした1例2016
- Author(s)
  吉野匠，松田兼一，森口武史，針井則一，後藤順子，原田大希，菅原久徳，高三野淳一，伊瀬洋史，渡邉愛乃
- Organizer
  第44回日本救急医学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪・国際館パミール（東京都・港区）
- Data Source
  KAKENHI-PROJECT-15K10971
[Presentation] ARDSに対するECMO+HFOVの試み2016
- Author(s)
  森口武史，松田兼一，針井則一，後藤順子，原田大希，菅原久徳，高三野淳一，吉野匠，伊瀬洋史，渡邉愛乃
- Organizer
  第44回日本救急医学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪・国際館パミール（東京都・港区）
- Data Source
  KAKENHI-PROJECT-15K10971
[Presentation] 連続腸音解析による腸音モニタリングシステムの臨床応用とその将来展望～医師の視点から～2016
- Author(s)
  後藤順子，松田兼一，針井則一，森口武史，柳沢政彦，原田大希，菅原久徳，高三野淳一，吉野匠，阪田治
- Organizer
  日本医工学治療学会
- Place of Presentation
  甲府富士屋ホテル(山梨県甲府市)
- Year and Date
  2016-03-19
- Data Source
  KAKENHI-PROJECT-15K10971
[Presentation] VA-ECMO離脱にNO吸入療法が有効であった心肺停止重症呼吸不全の1例2016
- Author(s)
  伊瀬洋史，松田兼一，森口武史，針井則一，後藤順子，原田大希，菅原久徳，高三野淳一，吉野匠，渡邉愛乃
- Organizer
  第19回日本救急医学会中部地方会総会・学術集会
- Place of Presentation
  名古屋大学医学部（愛知県・名古屋市）
- Data Source
  KAKENHI-PROJECT-15K10971
[Presentation] クラビット点眼により薬剤性肺障害を来した1例2016
- Author(s)
  菅原久徳，松田兼一，森口武史，針井則一，後藤順子，原田大希，高三野淳一，吉野匠，伊瀬洋史，渡邉愛乃
- Organizer
  第44回日本救急医学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪・国際館パミール（東京都・港区）
- Data Source
  KAKENHI-PROJECT-15K10971
[Presentation] 外来がん化学療法中に薬剤性肺胞出血から心肺停止に陥った一例2015
- Author(s)
  原田大希，松田兼一，森口武史，針井則一，後藤順子，柳沢政彦，菅原久徳，高三野淳一，吉野　匠
- Organizer
  第43回日本救急医学会
- Place of Presentation
  東京国際フォーラム(東京都千代田区)
- Year and Date
  2015-10-21
- Data Source
  KAKENHI-PROJECT-15K10971
[Presentation] ミャンマーにおける毒蛇咬傷AKIに対するonline-HDF治療の導入支援2015
- Author(s)
  原田大希，菅原久徳，後藤順子，針井則一，森口武史，松田兼一
- Organizer
  第60回日本透析医学会学術集会・総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2015-06-27
- Data Source
  KAKENHI-PROJECT-15K10971
[Presentation] 播腫性血管内凝固症候群を合併した敗血症に対するリコンビナントトロンボモジュリンの有効性の検討2015
- Author(s)
  菅原久徳，松田兼一，森口武史，針井則一，後藤順子，柳沢政彦，原田大希，高三野淳一，吉野　匠，長谷部洋平
- Organizer
  第24回日本集中治療医学会関東甲信越地方会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Year and Date
  2015-08-29
- Data Source
  KAKENHI-PROJECT-15K10971
[Presentation] 細径の中空糸を用いた小型血液浄化器の長時間安定施行条件の検討2015
- Author(s)
  栗原佳孝, 渡部紗己, 後田洋輔, 塚尾浩, 小林こず恵, 小久保謙一, 柳沢政彦, 後藤順子, 針井則一, 森口武史, 松田兼一, 小林弘祐
- Organizer
  第42回血液浄化技術学会学術大会・総会
- Place of Presentation
  東京都新宿区
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-15H05005
[Presentation] 肺炎球菌性肺炎による重症敗血症に続発し、診断に難渋したThrombotic Microangiopathyの一例2015
- Author(s)
  高三野淳一，松田兼一，森口武史，針井則一，柳沢政彦，後藤順子，原田大希，菅原久徳，吉野　匠
- Organizer
  第43回日本救急医学会
- Place of Presentation
  東京国際フォーラム(東京都千代田区)
- Year and Date
  2015-10-21
- Data Source
  KAKENHI-PROJECT-15K10971
[Presentation] 当院における研修医の初期診療研修と2次救急医療体制一体化の試み2015
- Author(s)
  森口武史，松田兼一，針井則一，後藤順子，柳沢政彦，原田大希，菅原久徳，高三野淳一，吉野　匠
- Organizer
  第43回日本救急医学会
- Place of Presentation
  東京国際フォーラム(東京都千代田区)
- Year and Date
  2015-10-23
- Data Source
  KAKENHI-PROJECT-15K10971
[Presentation] Effect of polyarylate/polyethylsulfon(PEPA) membrane hemofiltrati on on removal of serum interleukin(IL)-6 in rat experimental endotoxemia2013
- Author(s)
  針井則一
- Organizer
  第34回日本アフェレシス学会学術大会
- Place of Presentation
  軽井沢プリンスホテルウエスト（長野県北佐久郡軽井沢町軽井沢）
- Data Source
  KAKENHI-PROJECT-24592732
[Presentation] 重症敗血症患者における経腸栄養の認容性の評価,リアルタイム腸音解析システムの実用化の試み,第一報2012
- Author(s)
  針井則一, 松田兼一, 阪田治, 松岡憲弘, 柳沢政彦, 原田大希, 菅原久徳, 早川聖子, 丸山恵梨香
- Organizer
  第39回日本集中治療医学会学術集会
- Place of Presentation
  千葉,幕張
- Year and Date
  2012-03-01
- Data Source
  KAKENHI-PROJECT-22592011
[Presentation] 重症敗血症患者における経腸栄養の認容性の評価リアルタイム腸音解析システムの実用化の試み第一報2012
- Author(s)
  針井則一
- Organizer
  第39回日本集中治療医学会学術集会
- Year and Date
  2012-03-01
- Data Source
  KAKENHI-PROJECT-22592011

1. MATSUDA Kenichi (60282480)

# of Collaborated Projects: 6 results

# of Collaborated Products: 25 results
2. MORIGUCHI Takeshi (60422680)

# of Collaborated Projects: 6 results

# of Collaborated Products: 17 results
3. GOTO Junko (60530102)

# of Collaborated Projects: 6 results

# of Collaborated Products: 17 results
4. YANAGISAWA Masahiko (90597022)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
5. 武岡真司 (20222094)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 菅原久徳 (70746776)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. SAKATA Osamu (30391197)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. 宮坂武寛 (60308195)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
9. 高三野淳一 (70769281)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. AIDA Kaoru (50184015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KOBAYASHI Tetsuro (30113442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 原田大希 (70597020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
13. 山本健一郎 (00434316)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 山根隆志 (10358278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 小久保謙一 (20287965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 垣内健太 (30875422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 土田英俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results

HARII Norikazu 針井 則一

Research Projects

Research Products

Co-Researchers

ARDSモデルラットにおける短時間液体呼吸と新規薬物伝達システムの治療効果の検証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Total liquid ventilation with oxygen micro/nano bubble dispersion ameliorates lipopolysaccharide-induced acute respiratory distress syndrome in rats.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clinical application of the bowel sound monitoring system by real time bowel sound analysis in critical patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The possibility of therapeutic application of temporary total liquid ventilation in rat acute respiratory distress syndrome model.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Challenge to a portable blood purification system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Examination of a different membranes on cytokine adsorption on circulating cytokine and search of a biomarker as a prognosticator in a sepsis rat continuous heamodiafiltration modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of an intestines peristalsis monitoring system by thecontinuous bowel-sounds analysis in the critically ill patients

Principal Investigator

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Identification of genes that are involved in differentiation of pancreatic ductal cells to pancreatic β-cells.

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[Journal Article] Total alveolar lavage with oxygen fine bubble dispersion directly improves lipopolysaccharide-induced acute respiratory distress syndrome of rats2020

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[Journal Article] 重症患者における連続陽音解析システムの臨床応用2016

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[Journal Article] 重症患者における連続腸音解析システムの臨床応用2016

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NAID

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[Journal Article] 急性腎心症候群2015

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[Journal Article] 重症急性膵炎に対する血液浄化療法2015

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[Journal Article] 細径化したファイバを用いたヘモフィルタの開発2015

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[Patent] 蠕動音検出装置、蠕動音検出方法、プログラム、および記録媒体2012

Inventor(s)

HARII Norikazu 針井則一