NISHIGUCHI KOHSHI 西口工司

… Alternative Names

NISHIGUCHI Kohshi 西口工司

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Researcher Number	80379437
Other IDs
Affiliation (Current)	2025: 京都薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2013 – 2023: 京都薬科大学, 薬学部, 教授 2008 – 2010: Kyoto Pharmaceutical University, 薬学部, 教授
Review Section/Research Field	Principal Investigator Medical pharmacy / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Applied pharmacology
Keywords	Principal Investigator 食道癌 / 微小環境 / ビスホスホネート系薬物 / 食道がん / 耐性 / 低酸素環境 / 癌微小環境 / トリプルネガティブ乳癌 / PARP阻害薬 / 治療標的 … More / コレステロール合成 / ビスホスホネート / 低酸素 / がん微小環境 / 癌細胞 / ビスホスホネート系薬剤 / 細胞増殖抑制作用 / ホスホネート系薬剤 / 細胞周期 / アポトーシス / がん細胞 / 適正使用 / 代謝拮抗剤 / フッ化ピリミジン系 / がん化学療法 / 大腸癌 … More Except Principal Investigator 薬物相互作用 / OATP / 相互作用 / 消化管吸収 / クエン酸第二鉄 / 酸化マグネシウム / 炭酸カルシウム / ロスバスタチン / リン吸着薬 / 金属カチオン製剤 / 皮膚組織滞留性 / 皮膚障害 / 副作用 / SGLT2 阻害薬 / ヒト角化細胞・繊維芽細胞3 次元培養系 / SGLT2 阻害剤 / STAT3 / ヒト角化細胞・繊維芽細胞３次元培養系 / 皮膚組織移行性 / ipragliflozin / 重篤な皮膚障害 / SGLT2阻害剤 / 医薬品相互作用 / 末期腎不全患者 / SN-38 / 尿毒症物質 / 有機アニオン輸送ポリペプチド / 末期腎不全 / 有害事象 / 薬物有害事象 / 薬物トランスポーター / 薬物代謝酵素 / 慢性腎臓病 Less

トリプルネガティブ乳癌におけるPARP阻害剤耐性化の克服を目指した新規機序の解明Principal Investigator
- Principal Investigator
  
  西口工司
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kyoto Pharmaceutical University
Elucidation of the mechanisms of rosuvastatin concentration reduction by co-administration of the preparations of metal cation and application to other metal cation
- Principal Investigator
  
  Tsujimoto Masayuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kyoto Pharmaceutical University
Serious skin and subcutaneous disorders caused by a sodium-glucose co-transporter 2 inhibitor, ipragliflozin
- Principal Investigator
  
  Sakaeda Toshiyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kyoto Pharmaceutical University
Enhancement mechanisms of cell growth suppression by bisphosphonates in cancer microenvironmentPrincipal Investigator
- Principal Investigator
  
  NISHIGUCHI KOHSHI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Mechanism for unpredictable drug interaction in patients with chronic kidney disease
- Principal Investigator
  
  Tsujimoto Masayuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto Pharmaceutical University
Anticancer effects of bisphosphonates in human esophageal squamous cellPrincipal Investigator
- Principal Investigator
  
  NISHIGUCHI KOHSHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Appropriate use of the oral fluoropyrimidine anticancer drugs in patients with colorectal cancerPrincipal Investigator
- Principal Investigator
  
  NISHIGUCHI Kohshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto Pharmaceutical University

All 2024 2023 2022 2020 2019 2018 2017 2016 2015 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Acceleration of carboxylesterase-mediated activation of irinotecan to SN-38 by serum from patients with end-stage kidney disease2018
- Author(s)
  Koide Hiroyoshi、Tsujimoto Masayuki、Katsube Yurie、Ochiai Megumi、Hojo Ayako、Furukubo Taku、Izumi Satoshi、Yamakawa Tomoyuki、Shima Daisuke、Minegaki Tetsuya、Nishiguchi Kohshi
- Journal Title
  
  Cancer Chemotherapy and Pharmacology
  
  Volume: in press Issue: 6 Pages: 1121-1128
- DOI
  10.1007/s00280-018-3583-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08601
[Journal Article] Substrate-dependent effects of molecular-targeted anticancer agents on activity of organic anion transporting polypeptide 1B12018
- Author(s)
  Koide Hiroyoshi、Tsujimoto Masayuki、Takeuchi Ai、Tanaka Miyu、Ikegami Yoko、Tagami Mayu、Abe Syoko、Hashimoto Miki、Minegaki Tetsuya、Nishiguchi Kohshi
- Journal Title
  
  Xenobiotica
  
  Volume: in press Issue: 10 Pages: 1059-1071
- DOI
  10.1080/00498254.2017.1393582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08601
[Journal Article] Evaluation of Trace Elements in Augmentation of Statin-Induced Cytotoxicity in Uremic Serum-Exposed Human Rhabdomyosarcoma Cells2018
- Author(s)
  Uchiyama Hitoshi、Tsujimoto Masayuki、Shimada Naomi、Tsutsui Koji、Nitta Ayaka、Yoshida Takuya、Furukubo Taku、Izumi Satoshi、Yamakawa Tomoyuki、Tachiki Hidehisa、Minegaki Tetsuya、Nishiguchi Kohshi
- Journal Title
  
  Toxins
  
  Volume: 10 Issue: 2 Pages: 53-53
- DOI
  10.3390/toxins10020053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08601
[Journal Article] Augmentation of the cytotoxic effects of nitrogen-containing bisphosphonates in hypoxia2018
- Author(s)
  Tetsuya Minegaki, Saya Koiki, Yutaro Douke, Chihiro Yamane, Ai Suzuki, Misato Mori, Masayuki Tsujimoto, and Kohshi Nishiguchi
- Journal Title
  
  Journal of Pharmacy and Pharmacology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08423
[Journal Article] Cooperative inhibitory effects of uremic toxins and other serum components on OATP1B1-mediated transport of SN-382017
- Author(s)
  Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Megumi Ochiai, Ayako Hojyo, Kaori Ogawa, Kengo Kambara, Nao Torii, Daisuke Shima, Taku Furukubo, Satoshi Izumi, Tomoyuki Yamakawa, Tetsuya Minegaki, Kohshi Nishiguchi
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 79 Issue: 4 Pages: 783-789
- DOI
  10.1007/s00280-017-3276-y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08601
[Journal Article] Effects of bisphosphonates on human esophageal squamous cell carcinoma cell survival2015
- Author(s)
  Tetsuya Minegaki, Saori Fukushima, Chihiro Morioka, Hitomi Takanashi, Junki Uno, Shiori Tsuji, Satoshi Yamamoto, Airi Watanabe, Masayuki Tsujimoto, and Kohshi Nishiguchi
- Journal Title
  
  Dis. Esophagus
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460230
[Journal Article] Effect of dose-escalation of 5-fluorouracil on circadian variability of its pharmacokinetics in Japanese patients with Stage III/IVa esophageal squamous cell carcinoma.2010
- Author(s)
  Akiko Kuwahara, Motohiro Yamamori, Kohshi Nishiguchi, Tatsuya Okuno, Naoko Chayahara, Ikuya Miki, Takao Tamura, Kaori Kadoyama, Tsubasa Inokuma, Yoshiji Takemoto, Tsutomu Nakamura, Kazusaburo Kataoka, Toshiyuki Sakaeda
- Journal Title
  
  Int.J.Med.Sci. 7
  
  Pages: 48-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590144
[Journal Article] Replacement of cisplatin with nedaplatin in a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma.2009
- Author(s)
  Akiko Kuwahara, Motohiro Yamamori, Kohshi Nishiguchi, Tatsuya Okuno, Naoko Chayahara, Ikuya Miki, Takao Tamura, Tsubasa Inokuma, Yoshiji Takemoto, Tsutomu Nakamura, Kazusaburo Kataoka, Toshiyuki Sakaeda
- Journal Title
  
  Int.J.Med.Sci. 6
  
  Pages: 305-311
- NAID
  120001887679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590144
[Journal Article] Molecular changes to HeLa cells on continuous exposure to SN-38, an active metabolite of irinotecan hydrochloride.2009
- Author(s)
  Kohji Takara, Noriaki Kitada, Eri Yoshikawa, Kazuhiro Yamamoto, Sayo Horibe, Toshiyuki Sakaeda, Kohshi Nishiguchi, Noriaki Ohnishi, Teruyoshi Yokoyama
- Journal Title
  
  Cancer Lett. 278
  
  Pages: 88-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590144
[Journal Article] Three-dimensional, but not two-dimensional, culture results in tumor growth enhancement after exposure to anticancer drugs.2008
- Author(s)
  Chiho Komoto, Tsutomu Nakamura, Nobuko Ohmoto, Hironao Kobayashi, Tatsurou Yagami, Kohshi Nishiguchi, Koichi Iwaki, Akiko Kuwahara, Motohiro Yamamori, Noboru Okamura, Katsuhiko Okumura, Toshiyuki Sakaeda
- Journal Title
  
  Kobe J.Med.Sci. 53
  
  Pages: 335-343
- NAID
  110006648070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590144
[Presentation] PARP 阻害薬耐性ヒト乳癌細胞株の転移能に及ぼす低酸素環境の影響2024
- Author(s)
  山田奈月、吉田梨紗、德武陽渚、廣林柊吾、村山友菜、辻本雅之、西口工司
- Organizer
  日本薬学会第144年会（横浜）
- Data Source
  KAKENHI-PROJECT-23K06292
[Presentation] 消化管上皮Caco-2細胞におけるロスバスタチンの細胞内取り込みに及ぼすリン吸着剤の影響2023
- Author(s)
  小菅　真広，辻本　雅之，今宿　夏野，川本　真由香，中村　紗英，西口　工司
- Organizer
  第143年会日本薬学会
- Data Source
  KAKENHI-PROJECT-21K06721
[Presentation] 消化管上皮Caco-2細胞におけるロスバスタチンの細胞内取り込みに及ぼすリン吸着剤の影響2022
- Author(s)
  小菅真広，辻本雅之，今宿夏野，川本真由香，中村紗英，西口工司
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06721
[Presentation] ヒトケラチノサイトHaCaT細胞へのSGLT2阻害薬イプラクリフロジンの特異的な取り込みが細胞死を引き起こす2020
- Author(s)
  松下望、辻本雅之、田中慎子、折方琴音、白土恵理、辻本美莱、河渕真治、峯垣哲也、栄田敏之、西口工司
- Organizer
  第41回日本病院薬剤師会近畿学術大会（神戸）
- Data Source
  KAKENHI-PROJECT-18K06804
[Presentation] ヒト食道癌細胞株の低酸素環境下におけるビスホスホネートに対する感受性増強機序の解明2019
- Author(s)
  楠斐未、峯垣哲也、池上歩花、奥田博允、藤井啓子、眞弓万里奈、北山純花、原祢幸汰、葛本貴大、米田朋美、辻本雅之、西口工司
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08423
[Presentation] Effects of uremic serum on statin-induced cytotoxicity and its mechanism2017
- Author(s)
  Hitoshi Uchiyama, Masayuki Tsujimoto, Tadakazu Shinmoto, Hitomi Ogino, Tomoko Oda, Ayaka Nitta, Koji Tsutsui, Naomi Shimada, Takuya Yoshida, Taku Furukubo, Satoshi Izumi, Tomoyuki Yamakawa, Hidehisa Tachiki, Tetsuya Minegaki, Kohshi Nishiguchi
- Organizer
  2017AAPS Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08601
[Presentation] OATP1B1を介した基質の取り込みに及ぼす分子標的薬の影響2017
- Author(s)
  田中美優、辻本雅之、小出博義、竹内あい、池上葉子、田上真優、阿部祥子、橋本実季、峯垣哲也、西口工司
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-15K08601
[Presentation] 低酸素下におけるビスホスホネート系薬物の細胞毒性増強とそのメカニズムの解明2017
- Author(s)
  峯垣哲也、戀木沙耶、道家雄太郎、山根千尋、鈴木　藍、森　美里、辻本雅之、西口工司
- Organizer
  日本薬学会　第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K08423
[Presentation] 末期腎不全患者においてコルヒチン及びクラリスロマイシンの相互作用が重篤化するメカニズムの解明2017
- Author(s)
  下野香帆、辻本雅之、内山仁、板谷あゆみ、古久保拓、和泉　智、立木秀尚、山川智之、峯垣哲也、西口工司
- Organizer
  第38回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-15K08601
[Presentation] 低酸素環境下における食道癌細胞株に対するビスホスホネートによる細胞増殖抑制作用の増強2016
- Author(s)
  山根千尋、峯垣哲也、戀木沙耶、道家雄太郎、鈴木藍、森美里、辻本雅之、西口工司
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25460230
[Presentation] Hypoxia Potentiates the Cytotoxic Effects of Nitrogen-Containing Bisphosphonates in Human Esophageal Cancer Cell Line.2016
- Author(s)
  Kohshi Nishiguchi, Tetsuya Minegaki, Saya Koiki, Yutaro Doke, Chihiro Yamane, Ai Suzuki, Misato Mori, Masayuki Tsujimoto
- Organizer
  2016 AAPS Annual Meeting and Exposition
- Place of Presentation
  Denver, Colorado, USA
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08423
[Presentation] The Identification of the Mechanism of Elevated Plasma Concentration of SN-38 in Patients with Endstage Kidney Disease:Focus on Metabolic Enzymes and Transporter in the Liver.2016
- Author(s)
  Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Megumi Ochiai, Ayako Hojyo, Daisuke Shima,Taku Furukubo, Satoshi Izumi, Tomoyuki Yamakawa, Tetsuya Minegaki, Kohshi Nishiguchi
- Organizer
  2016 AAPS Annual Meeting and Exposition
- Place of Presentation
  Denver, Colorado, USA
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08601
[Presentation] 低酸素下でのビスホスホネート系薬剤による細胞毒性の増強におけるメバロン酸経路の関与2016
- Author(s)
  戀木沙耶、峯垣哲也、道家雄太郎、山根千尋、鈴木　藍、森　美里、辻本雅之、西口工司
- Organizer
  医療薬学フォーラム2016　第24回クリニカルファーマシーシンポジウム
- Place of Presentation
  滋賀県大津市
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-16K08423
[Presentation] 末期腎不全患者血清を曝露させた大腸がん由来細胞株におけるSN-38感受性の低下2016
- Author(s)
  小澤将一、辻本雅之、内山仁、伊藤なつこ、森下智恵、入江怜祐、坂下透子、山本瑞紀、古久保拓、和泉智、立木秀尚、山川智之、峯垣哲也、西口工司
- Organizer
  日本薬学会第136年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K08601
[Presentation] アリスキレンの肝消失過程に及ぼす有機アニオン輸送ポリポプチド1B1及び1B3の関与2016
- Author(s)
  入江裕子、辻本雅之、吉田拓弥、藤岡春乃、川上祥代、中谷沙紀、住本菜摘、須本真理子、中川智加、松本光司、峯垣哲也、西口工司
- Organizer
  日本薬学会第136年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K08601
[Presentation] 低酸素環境下におけるヒト食道癌細胞株の増殖に及ぼすビスホスホネート系薬物の影響2015
- Author(s)
  道家雄太郎、峯垣哲也、戀木沙耶、山根千尋、鈴木　藍、森　美里、辻本雅之、西口工司
- Organizer
  第25回日本医療薬学会年会
- Place of Presentation
  横浜
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-25460230
[Presentation] OATP1B1を介したプラバスタチン輸送に及ぼす末期腎不全患者血清の影響2015
- Author(s)
  木村朱李、辻本雅之、内山　仁、結城絵理子、佐伯　崇、吉田拓弥、古久保拓、和泉　智、山川智之、峯垣哲也、西口工司
- Organizer
  第9回日本腎臓病薬物療法学会学術集会・総会2015
- Place of Presentation
  宮城県仙台市
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-15K08601
[Presentation] 5-FU並びに抗腫瘍性白金錯体に対する感受性規定因子の探索2010
- Author(s)
  濱口良平, 高良恒史, 峯垣哲也, 辻本雅之, 栄田敏之, 西口工司
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20590144
[Presentation] 大腸癌細胞での抗腫瘍性白金錯体及び5-FUの感受性を規定する要因の探索2010
- Author(s)
  峯垣哲也, 高良恒史, 濱口良平, 藪田直希, 辻本雅之, 西口工司
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20590144
[Presentation] 網羅的遺伝子発現解析に基づいた抗腫瘍性白金錯体感受性因子の探索2009
- Author(s)
  藪田直希, 高良恒史, 峯垣哲也, 北田徳昭, 辻本雅之, 西口工司, 横山照由
- Organizer
  第19回日本医療薬学会年会
- Place of Presentation
  長崎
- Year and Date
  2009-10-25
- Data Source
  KAKENHI-PROJECT-20590144
[Presentation] 抗癌剤調製におけるシリンジによる測定誤差について2008
- Author(s)
  多田恵理、打保裕子、藤田恵、丸上奈穂、山道俊彦、山本麻央、堂下真梨、和田敦、角山香織、槇本博雄、西口工司、平井みどり
- Organizer
  第18回日本医療薬学会年会
- Place of Presentation
  札幌
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-20590144
[Presentation] ヒト食道癌細胞株におけるビスホスホネート系薬物の増殖抑制作用とそのメカニズムの解明
- Author(s)
  高梨仁美、峯垣哲也、宇野順騎、福島沙織、森岡千尋、辻本雅之、西口工司
- Organizer
  第3回４大学連携研究フォーラム
- Place of Presentation
  京都府立医科大学
- Data Source
  KAKENHI-PROJECT-25460230
[Presentation] 食道癌細胞に対するビスホスホネート系薬物の細胞増殖抑制作用
- Author(s)
  森岡千尋、峯垣哲也、宇野順騎、高梨仁美、福島沙織、辻栞、山本知志、渡邊愛梨、辻本雅之、西口工司
- Organizer
  第63回　日本薬学会近畿支部総会・大会
- Place of Presentation
  同志社女子大学薬学部
- Data Source
  KAKENHI-PROJECT-25460230
[Presentation] ビスホスホネート系薬物のヒト食道癌細胞株に対する細胞毒性メカニズムの解明
- Author(s)
  峯垣哲也、森岡千尋、福島沙織、高梨仁美、宇野順騎、辻　栞、山本知志、渡邉愛梨、辻本雅之、西口工司
- Organizer
  第24回日本医療薬学会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-09-27 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-25460230
[Presentation] ヒト食道癌細胞株の増殖に及ぼすビスホスホネート系薬物の影響
- Author(s)
  福島沙織、峯垣哲也、宇野順騎、高梨仁美、森岡千尋、辻栞、山本知志、渡邊愛梨、辻本雅之、西口工司
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本市総合体育館
- Data Source
  KAKENHI-PROJECT-25460230

1. Tsujimoto Masayuki (90372739)

# of Collaborated Projects: 5 results

# of Collaborated Products: 26 results
2. Minegaki Tetsuya (10549306)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
3. SAKAEDA Toshiyuki (00304098)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. HIRAI Midori (70228766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. MINAMI Hironobu (60450574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TAMURA Takao (80324929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. YAMAMORI Motohiro (10444613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

NISHIGUCHI KOHSHI 西口 工司

NISHIGUCHI Kohshi 西口 工司

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トリプルネガティブ乳癌におけるPARP阻害剤耐性化の克服を目指した新規機序の解明Principal Investigator

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Elucidation of the mechanisms of rosuvastatin concentration reduction by co-administration of the preparations of metal cation and application to other metal cation

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Serious skin and subcutaneous disorders caused by a sodium-glucose co-transporter 2 inhibitor, ipragliflozin

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Enhancement mechanisms of cell growth suppression by bisphosphonates in cancer microenvironmentPrincipal Investigator

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Mechanism for unpredictable drug interaction in patients with chronic kidney disease

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Anticancer effects of bisphosphonates in human esophageal squamous cellPrincipal Investigator

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Appropriate use of the oral fluoropyrimidine anticancer drugs in patients with colorectal cancerPrincipal Investigator

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[Journal Article] Acceleration of carboxylesterase-mediated activation of irinotecan to SN-38 by serum from patients with end-stage kidney disease2018

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[Journal Article] Substrate-dependent effects of molecular-targeted anticancer agents on activity of organic anion transporting polypeptide 1B12018

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[Journal Article] Evaluation of Trace Elements in Augmentation of Statin-Induced Cytotoxicity in Uremic Serum-Exposed Human Rhabdomyosarcoma Cells2018

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[Journal Article] Augmentation of the cytotoxic effects of nitrogen-containing bisphosphonates in hypoxia2018

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[Journal Article] Cooperative inhibitory effects of uremic toxins and other serum components on OATP1B1-mediated transport of SN-382017

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[Journal Article] Effects of bisphosphonates on human esophageal squamous cell carcinoma cell survival2015

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[Journal Article] Effect of dose-escalation of 5-fluorouracil on circadian variability of its pharmacokinetics in Japanese patients with Stage III/IVa esophageal squamous cell carcinoma.2010

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[Journal Article] Replacement of cisplatin with nedaplatin in a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma.2009

NISHIGUCHI KOHSHI 西口工司

NISHIGUCHI Kohshi 西口工司