OHBA Tomoyuki 大場誠介

… Alternative Names

大場誠介オオバトモユキ

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Researcher Number	80380666
Other IDs
Affiliation (based on the past Project Information) *help	2011: 法政大学, 企画戦略本部, 特任准教授 2009 – 2011: Tohoku University, 大学院・生命科学研究科, 助教 2006: 東北大学, 大学院・生命科学研究科, 助手 2005: 九州大学, 医学研究院, 特任助手
Review Section/Research Field	Principal Investigator Applied genomics / Cell biology Except Principal Investigator General medical chemistry / Pathological medical chemistry
Keywords	Principal Investigator IκB-ζ / 染色体 / 核構造 / シグナル伝達 / 転写因子 / 染色体構造 / lumen構造物 / タンパク質の輸送制限 / 抗体のmicroinjection / rapamycin誘導複合体 … More / 核膜孔 / 生きた細胞内での実験系 / 核の外膜から内膜への輸送機構 / 核膜タンパク質 … More Except Principal Investigator IκB-ζ / シグナル伝達 / Signaling / mRNA Stabilization / Regulation of Transcription / Innate Immunity / mRNA安定化 / 転写制御 / 自然免疫 / NF-κB / 炎症 / 免疫学 / 発現制御 / 細胞・組織 / 遺伝子 / 自己免疫疾患 / B細胞 / 上皮細胞 / アポトーシス / シェーグレン症候群 / 慢性炎症 / 核内IκBファミリー / 分子病態学 Less

Investigating the relationship between the conformation of nuclear membrane and the functions of chromatinPrincipal Investigator
- Principal Investigator
  
  OHBA Tomoyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Applied genomics
- Research Institution
  Hosei University
  Tohoku University
Function of Inducible Transcriptional Regulators in Regulation of Inflammatory Reactions in Homeostasis and Its Dysregulation.
- Principal Investigator
  
  MUTA Tatsushi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
核の内膜タンパク質の小胞体から内膜への輸送機構の解明Principal Investigator
- Principal Investigator
  
  大場誠介
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Tohoku University
  Kyushu University
Studies on stimulus-specific induction of a novel NF-κB regulator, IκB-ζ, and its physiological roles
- Principal Investigator
  
  TAKESHIGE Koichiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  KYUSHU UNIVERCITY

All 2013 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Transcriptional and post-transcriptional regulation of IκB-ζ upon engagement of BCR, TLR and Fcγ receptor2013
- Author(s)
  Hanihara, F. et al.
- Journal Title
  
  International Immunology
  
  Volume: 印刷中 Issue: 9 Pages: 531-544
- DOI
  10.1093/intimm/dxt017
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21117004, KAKENHI-PROJECT-21390088, KAKENHI-PROJECT-24390076
[Journal Article] Enhanced Apoptosis by Disruption of the STAT3-I κ B-ζ Signaling Pathway in Epithelial Cells Induces Sjogren' S Syndrome-like Autoimmune Disease.2013
- Author(s)
  大熊敦史
- Journal Title
  
  Immunity
  
  Volume: 38 Issue: 3 Pages: 450-460
- DOI
  10.1016/j.immuni.2012.11.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04191, KAKENHI-ORGANIZER-21117001, KAKENHI-PLANNED-21117004, KAKENHI-PROJECT-21390088, KAKENHI-PROJECT-22590345, KAKENHI-PROJECT-22590444, KAKENHI-PROJECT-23390124, KAKENHI-PROJECT-23659245, KAKENHI-PROJECT-23659541, KAKENHI-PROJECT-24390076, KAKENHI-PLANNED-21117003
[Journal Article]2012
- Author(s)
  Tomoyuki Ohba, Yujiro Ariga, Takashi Maruyama, Nha K. Truong, Jun-ichiro Inoue, Tatsushi Muta
- Journal Title
  
  FEBS Journal
  
  Volume: 279(2) Pages: 211-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200040
[Journal Article] Identification of interleukin-1 receptor-associated kinase 1 as a critical component that induces post-transcriptional activation of IκB-ζ2012
- Author(s)
  Ohba T, Ariga Y, Maruyama T, Truong NK, Inoue J, Muta T
- Journal Title
  
  The FEBS Journal
  
  Volume: 279 Issue: 2 Pages: 211-222
- DOI
  10.1111/j.1742-4658.2011.08416.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06972, KAKENHI-PROJECT-21200040, KAKENHI-PROJECT-21390088, KAKENHI-ORGANIZER-22117001, KAKENHI-PLANNED-22117002, KAKENHI-PROJECT-22590345
[Presentation] IkB-ζ-deficiency in Non-lympoid Cells Spontaneously Induces Autoimmune Reactions2011
- Author(s)
  OKUMA Atsushi, OHBA Tomoyuki, ONO Masao, MUTA Tatsushi
- Organizer
  第40回日本免疫学会総会
- Place of Presentation
  千葉県千葉市幕張メッセ
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Induction of IkB-ζ by Activations of Transcription and Post-transcriptional Regulation on B Cell Receptor Stimulation2011
- Author(s)
  Fumito Hanihara, Tomoyuki Ohba, Tatsushi Muta
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Induction of IκB-ζ by Activations of Transcription and Post-transcriptional Regulation on B Cell Receptor Stimulation2011
- Author(s)
  Hanihara F., Ohba T., Muta T.
- Organizer
  第34回日本分子生物学
- Place of Presentation
  横浜パシフィコ横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Chemokine Induction in Macrophages as a Response to Necrotic Cells2011
- Author(s)
  Kimura, T., Watanabe, E., Hanihara, F., Ohba, T., and ○Muta, T.
- Organizer
  Toll2011 Meeting-Decoding InnateImmunity (Poster)
- Place of Presentation
  Riva del Garda, Italy
- Data Source
  KAKENHI-PROJECT-21390088
[Presentation] IκB-ζ-deficiency in Non-lymphoid Cells Spontaneously Induces Autoimmune Reactions2011
- Author(s)
  Okuma A., Ohba T., Ono M., Muta T.
- Organizer
  第40回日本免疫学会総会
- Place of Presentation
  千葉幕張メッセ
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Chronic Skin Inflammation Developed in Mice Lacking IκB-ζ, Crucial NF-κB Regulator2010
- Author(s)
  大熊敦史, 大場誠介, 牟田達史
- Organizer
  Keystone Symposium "NF-κB in Inflammation and Disease
- Place of Presentation
  サンタフェ、アメリカ
- Year and Date
  2010-01-07
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Molecular Dissection of the MyD88-dependent Signaling that Leads to Specific mRNA Stabilization2010
- Author(s)
  Yuziro Ariga, Fumito Hanihara, Tomoyuki Ohba, Tatsushi Muta
- Organizer
  Keystone Symposia Meeting Innate Immunity : Mechanisms Linking with Adaptive Immunity
- Place of Presentation
  Dublin, Ireland
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Stimulus-specific Post-transcriptional Regulation of IκB-ζ in Innate and Adaptive Immune Responses2010
- Author(s)
  Fumito Hanihara, Yuta Takahashi, Tomoyuki Ohba, Tatsushi Muta
- Organizer
  The 11th Annual Meeting of The Society for Leukocyte Biology & The International Endotoxin and Innate Immunity Society
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Stimulus-specific Post-transcriptional Regulation of IκB-ζ in Innate and Adaptive Immune Responses2010
- Author(s)
  Hanihara F., Takahashi Y., Ohba T., Muta T.
- Organizer
  The 11th annual IEIIS meeting
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Identification of the Toll-like receptor signaling components involved in the post-transcriptional regulation of IκB-ζ2010
- Author(s)
  Yuziro Ariga, Tomoyuki Ohba, Truong N.K., Tatsushi Muta
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan(大場発表)
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Stimulus-specific post-transcriptional regulation of IκB-ζ, an essential regulator on inflammatory responses2010
- Author(s)
  Fumito Hanihara, Yuta Takahashi, Tomoyuki Ohba, Tatsushi Muta
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Roles for Lymphocytes and Non-hematopoietic Cells in the Pathogenesis of Chronic Skin Inflammation in IκB-ζ-deficient Mice2010
- Author(s)
  Okuma A., Ohba T., Muta T.
- Organizer
  The 11th Annual Meeting of The Society for Leukocyte Biology & The International Endotoxin and Innate Immunity Society
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Stimulus-specific Post-transcriptional Regulation of IκB-ζ, an Essential Regulator on Inflammatory Responses2010
- Author(s)
  Hanihara, F., Takahashi, Y., Ohba, T., and Muta, T.
- Organizer
  14th International Congress of Immunology (Poster)
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-21390088
[Presentation] Identification of the Toll-like Receptor Signaling Components Involved in the Post-transcriptional Regulation of IκB-ζ2010
- Author(s)
  Ohba, et al
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21390088
[Presentation] Stimulus-specificPost-transcriptional Regulation of IκB-ζ in Innate and Adaptive Immune Responses2010
- Author(s)
  Hanihara, F., Takahashi, Y., Ohba, T., and Muta, T.
- Organizer
  2010 Joint Annual Meeting between the Society for Leukocyte Biology and the International Endotoxin & Innate Immunity Society
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-21390088
[Presentation] Chronic Skin Inflammation Developed in Mice Lacking IκB-ζ, a Crucial NF-κB Regulator2010
- Author(s)
  Okuma, A., Ohba, T., and Muta, T.
- Organizer
  Keystone Symposium "NF-κB in Inflammation and Disease" (Poster)
- Place of Presentation
  Santa Fe, NewMexico, USA
- Data Source
  KAKENHI-PROJECT-21390088
[Presentation] Identification of the Toll-like receptor signaling components involved in the post-transcriptional regulation of IκB-ζ2010
- Author(s)
  Ariga Y., Ohba T., Truong N. K., Muta T.
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan, Kobe Convention Center Complex
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Chemokines induction of macrophages in response to dead cells2010
- Author(s)
  Toshifumi Kimura, Emi Watanabe, Fumito Hanihara, Tomoyuki Ohba, Tatsushi Muta
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Analysis on the Pathogenesis of Chronic Skin Inflammation that Spontaneously Develops in IκB-ζ Gene-deficient Mice2010
- Author(s)
  Okuma, A., Ohba, T., Ono, M., Shibuya, S., Aiba, S., and Muta, T
- Organizer
  14th International Congress of Immunology (Poster)
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-21390088
[Presentation] Analysis on the pathogenesis of chronic skin inflammation that spontaneously develops in IκB-ζ gene-deficient mice2010
- Author(s)
  Okuma A., Ohba T., Ono M., Shibuya S., Aiba S., Muta T.
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan, Kobe Convention Center Complex
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Molecular Dissection of the MyD88-dependent Signaling that Leads to Specific mRNA Stabilization2010
- Author(s)
  Ariga, Y., Hanihara, F., Ohba, T., and Muta, T.
- Organizer
  Keystone Symposium "Innate Immunity"
- Place of Presentation
  Dublin, Ireland
- Data Source
  KAKENHI-PROJECT-21390088
[Presentation] Analysis on the pathogenesis of chronic skin inflammation that spontaneously develops in IκB-ζ gene-deficient mice2010
- Author(s)
  Atsushi Okuma, Tomoyuki Ohba, Tatsushi Muta
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Roles for Lymphocytes and Non-hematopoietic Cells in the Pathogenesis of Chronic Skin Inflammation in IκB-ζdeficient Mice2010
- Author(s)
  Okuma, A., Ohba, T., and Muta, T.
- Organizer
  2010 Joint Annual Meeting between the Society for Leukocyte Biology and the International Endotoxin & Innate Immunity Society
- Place of Presentation
  Vancouver, BC, Canada
- Data Source
  KAKENHI-PROJECT-21390088
[Presentation] Chronic Skin Inflammation Developed in　Mice Lacking IκB-ζ, Crucial NF-κB Regulator2010
- Author(s)
  Okuma A., Ohba T., Muta T.
- Organizer
  Keystone Symposia Meeting NF-κB in Inflammation and Disease
- Place of Presentation
  Santa Fe, USA
- Year and Date
  2010-01-07
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Stimulus-specific post-transcriptional regulation of IκB-ζ, an essential regulator on inflammatory responses2010
- Author(s)
  Hanihara F., Takahashi Y., T. Ohba T., Muta T.
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan, Kobe Convention Center Complex
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Chemokines induction of macrophages in response to dead cells2010
- Author(s)
  Kimura T., Watanabe E., Hanihara F., Ohba T., Muta T.
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan, Kobe　Convention Center Complex
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Molecular Dissection of the MyD88-dependent Signaling that Leads to Specific mRNA Stabilization2010
- Author(s)
  Ariga Y., Hanihara F., Ohba T., Muta T.
- Organizer
  Keystone Symposia Meeting Innate Immunity: Mechanisms Linking with Adaptive Immunity
- Place of Presentation
  Dublin, Ireland
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Chemokines Induction of Macrophages in Response to Dead Cells2010
- Author(s)
  Kimura, T., Watanabe, E., Hanihara, F., Ohba, T. and Muta, T
- Organizer
  14th International Congress of Immunology (Poster)
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-21390088
[Presentation] Mechanisms for stimulus-specific post-transcriptional regulation that determines induction of ＩκB-ζ, an essential regulator for selective gene expression on inflammatory responses2009
- Author(s)
  埴原文人、高橋優太、大場誠介、牟田達史
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜パシフィコ横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] IκB-ζ結合タンパク質としてのTAB2の同定とそのIκB-ζ依存性転写活性化における関与2009
- Author(s)
  大坪茂記、有賀裕二郎、大場誠介、牟田達史
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Mechanism for Stimulus-specific Post-transcriptional Regulation of IκB-ζ, which Controls Selective Gene Expression in Inflammatory Responses2009
- Author(s)
  埴原文人、高橋優太、大場誠介、牟田達史
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸神戸国際会議場
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Mechanisms for stimulus-specific post-transcriptional regulation that determines induction of IκB-z, an essential regulator for selective gene expression on inflammatory responses2009
- Author(s)
  埴原文人、高橋優太、大場誠介、牟田達史
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] IκB-ζ遺伝子欠損マウスにおける慢性皮膚炎の発症機序の解析2009
- Author(s)
  大熊敦史、大場誠介、小野栄夫、渋谷佐和子、相場節也、牟田達史
- Organizer
  第6回東北大学バイオサイエンスシンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-06-16
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] IκB-ζ結合タンパク質としてのTAB2 の同定とそのIκB-ζ依存性転写活性化における関与2009
- Author(s)
  大坪茂記、有賀裕二郎、大場誠介、牟田達史
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜パシフィコ横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] エストロゲン受容体との融合タンパク質を活用したToll-like Receptorシグナル伝達因子の活性操作系の確立2009
- Author(s)
  有賀裕二郎、大場誠介、Nha K. Truong、牟田達史
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜パシフィコ横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] エストロゲン受容体との融合タンパク質を活用した Toll-like Receptor シグナル伝達因子の活性操作系の確立2009
- Author(s)
  有賀裕二郎、大場誠介、Nha K.Truong、牟田達史
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] IκB-ζ遺伝子欠損マウスにおける慢性皮膚炎の発症機序の解析2009
- Author(s)
  大熊敦史、大場誠介、小野栄夫、渋谷佐和子、相場節也、牟田達史
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] IκB-ζ遺伝子欠損マウスにおける慢性皮膚炎の発症機序の解析2009
- Author(s)
  大熊敦史、大場誠介、小野栄夫、渋谷佐和子、相場節也、牟田達史
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪大阪国際会議場
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21200040
[Presentation] Mechanism for Stimulus-specific Post-transcriptional Regulation of I□B-□, which Controls Selective Gene Expression in Inflammatory Responses2009
- Author(s)
  埴原文人、高橋優太、大場誠介、牟田達史
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21200040

1. MUTA Tatsushi (60222337)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. TAKESHIGE Koichiro (10037450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. YAMAZAKI Soh (70315084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 大熊敦史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

OHBA Tomoyuki 大場 誠介

大場 誠介 オオバ トモユキ

Research Projects

Research Products

Co-Researchers

Investigating the relationship between the conformation of nuclear membrane and the functions of chromatinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Function of Inducible Transcriptional Regulators in Regulation of Inflammatory Reactions in Homeostasis and Its Dysregulation.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

核の内膜タンパク質の小胞体から内膜への輸送機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on stimulus-specific induction of a novel NF-κB regulator, IκB-ζ, and its physiological roles

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Transcriptional and post-transcriptional regulation of IκB-ζ upon engagement of BCR, TLR and Fcγ receptor2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhanced Apoptosis by Disruption of the STAT3-I κ B-ζ Signaling Pathway in Epithelial Cells Induces Sjogren' S Syndrome-like Autoimmune Disease.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article]2012

Author(s)

Journal Title

Data Source

[Journal Article] Identification of interleukin-1 receptor-associated kinase 1 as a critical component that induces post-transcriptional activation of IκB-ζ2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] IkB-ζ-deficiency in Non-lympoid Cells Spontaneously Induces Autoimmune Reactions2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Induction of IkB-ζ by Activations of Transcription and Post-transcriptional Regulation on B Cell Receptor Stimulation2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Induction of IκB-ζ by Activations of Transcription and Post-transcriptional Regulation on B Cell Receptor Stimulation2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Chemokine Induction in Macrophages as a Response to Necrotic Cells2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] IκB-ζ-deficiency in Non-lymphoid Cells Spontaneously Induces Autoimmune Reactions2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Chronic Skin Inflammation Developed in Mice Lacking IκB-ζ, Crucial NF-κB Regulator2010

Author(s)

Organizer

OHBA Tomoyuki 大場誠介

大場誠介オオバトモユキ