SHIMAZAWA Masamitsu 嶋澤雅光

Researcher Number	80381721
Other IDs
Affiliation (Current)	2025: 岐阜薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 岐阜薬科大学, 薬学部, 教授 2007 – 2020: Gifu Pharmaceutical University, 薬学部, 准教授 2005 – 2006: 岐阜薬科大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Ophthalmology / Basic Section 56060:Ophthalmology-related Except Principal Investigator Ophthalmology / Basic Section 37030:Chemical biology-related / Basic Section 56060:Ophthalmology-related
Keywords	Principal Investigator 網膜神経節細胞 / 緑内障 / 小胞体ストレス / エクソソーム / 薬理学 / 神経科学 / 眼薬理学 / βアミロイド / 糖尿病網膜症 / アルツハイマー病 … More Except Principal Investigator … More 緑内障 / PET / 眼科学 / サル / 眼圧 / 眼科 / 脳・神経 / 神経科学 / ヘム / オミクス解析 / 蛍光プローブ / イメージング / non-coding RNA / 滲出型加齢黄斑変性 / 線維化 / Retinal damage / Early therapy / Fundal change / Ophthalmology / Optic nerve damage / High intraocular pressure / Glaucoma / 網膜障害 / 早期診断 / 眼底変化 / 視神経障害 / 高眼圧 / 家兎眼の緑内障手術に対する組織反応 / 緑内障手術と予後 / 緑内障手術と視機能 / 緑内障手術と組織反応 / 眼圧と形態変化 / 緑内障手術 / ミクログリア / p38 / Ox-ATP / 視神経挫滅モデル / IL-1β / TNF-α / BBG / OxATP / 急性眼圧上昇モデル / P2X7受容体 / ラット / 網膜神経節細胞 / 眼圧上昇 / 視神経挫滅 / P2X7 受容体 Less

滲出型加齢黄斑変性の線維化病変に発現する新規ncRNAの機能解析
- Principal Investigator
  
  中村信介
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Gifu Pharmaceutical University
Chemical-tool-driven research on heme dynamics
- Principal Investigator
  
  平山祐
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Gifu Pharmaceutical University
Discovery of pathogenesis-related biomarkers from blood exosome analysis in glaucomatous optic neuropathyPrincipal Investigator
- Principal Investigator
  
  Shimazawa Masamitsu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Gifu Pharmaceutical University
Development of therapeutic drugs targeting VGF-modifying peptides in retinal diseasesPrincipal Investigator
- Principal Investigator
  
  Shimazawa Masamitsu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University
Structural and morphorogical changes after glaucoma surgery
- Principal Investigator
  
  ISHIDA Kyoko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Toho University
A study for protective mechanisms of VGF, a neurosecretory peptide, in glaucomatous optic nerve degenerationPrincipal Investigator
- Principal Investigator
  
  Shimazawa Masamitsu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University
A study for protective mechanisms of VGF, a neurosecretory peptide, in retinal injuryPrincipal Investigator
- Principal Investigator
  
  SHIMAZAWA Masamitsu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University
Involvement of activated P2X7 receptor in disorder of retinal ganglion cells in animal models of glaucoma
- Principal Investigator
  
  SUGIYAMA Tetsuya
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Osaka Medical College
Morphological and functional changes in visual cortex after retinal damage and its pharmacological approach
- Principal Investigator
  
  HARA Hideaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University
A study of molecular mechanisms of endoplasmic reticulum stress in retinal ganglion cell deathPrincipal Investigator
- Principal Investigator
  
  SHIMAZAWA Masamitsu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University
Changes in visual fields and retinal function in high intraocular pressure model of monkeys
- Principal Investigator
  
  HARA Hideaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University
緑内障及び糖尻病網膜症の病態におけるアルツハイマー病の関連性についてPrincipal Investigator
- Principal Investigator
  
  嶋澤雅光
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University
Functional changes mediated by high-intraocular pressure-induced optic nerve damage in lateral geniculate body and visual cortex of monkeys.
- Principal Investigator
  
  HARA Hideaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University

[Book] Central changes in glaucoma : Neuroscientific study using animal models, In : The Mystery of Glaucoma (eds. by Tomas Kubena), chapter 172011
- Author(s)
  Imamura K., Shimazawa M., Onoe H., Watanabe Y., Ishii K., Mayama C., Akasaki T., Shimegi S., Sato H., Nakadate K., Hara H., Araie M.
- Total Pages
  24
- Publisher
  InTech, Croatia
- Data Source
  KAKENHI-PROJECT-21592262
[Book] Central changes in glaucoma : Neuroscientific study using animal models, In : The Mystery of Glaucoma2011
- Author(s)
  Imamura K., Shimazawa M., Onoe H., Watanabe Y., Ishii K., Mayama C., Akasaki T., Shimegi S., Sato H., Nakadate K., Hara H. and Araie M.
- Total Pages
  17
- Publisher
  InTech, Croatia
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] VGF nerve growth factor inducible is involved in retinal ganglion cells death induced by optic nerve crush2018
- Author(s)
  Takeuchi Hiroto、Inagaki Satoshi、Morozumi Wataru、Nakano Yukimichi、Inoue Yuki、Kuse Yoshiki、Mizoguchi Takahiro、Nakamura Shinsuke、Funato Michinori、Kaneko Hideo、Hara Hideaki、Shimazawa Masamitsu
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 16443-16443
- DOI
  10.1038/s41598-018-34585-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18J14970, KAKENHI-PROJECT-17K11486
[Journal Article] Movement of retinal vessels toward the optic nerve head after increasing intraocular pressure in monkey eyes with experimental glaucoma2017
- Author(s)
  Kuroda A, Enomoto N, Ishida K, Shimazawa M, Noguchi T, Horai N, Onoe H, Hara H, Tomita G
- Journal Title
  
  Exp Eye Res
  
  Volume: 162 Pages: 110-115
- DOI
  10.1016/j.exer.2017.07.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462634
[Journal Article] Involvement of endoplasmic reticulum stress in optic nerve degeneration after chronic high intraocular pressure in DBA/2J mice.2015
- Author(s)
  Ojino K., Shimazawa M., Izawa H., Nakano Y., Tsuruma K. and Hara H
- Journal Title
  
  J. Neurosci. Res.
  
  Volume: 93 Issue: 11 Pages: 1675-1683
- DOI
  10.1002/jnr.23630
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462694
[Journal Article] Establishment of the ocular hypertension model using the common marmoset2013
- Author(s)
  Shimazawa, M., Nakamura, S., Miwa, M., Tsuruma, K., Aihara, M., Nakamura, K., Hara, H
- Journal Title
  
  Exp Eye Res
  
  Volume: 111 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592612
[Journal Article] Establishment of the ocular hypertension model using the common marmoset2013
- Author(s)
  Masamitsu Shimazawa, Shinsuke Nakamura, Miki Miwa, Kazuhiro Tsuruma, Makoto Aihara, Katsuki Nakamura, Hideaki Hara
- Journal Title
  
  Experimental Eye Research
  
  Volume: 111C Pages: 1-8
- DOI
  10.1016/j.exer.2013.03.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592612
[Journal Article] 緑内障:眼圧非依存障害因子への挑戦-ネズミ・サル・そしてヒトへ-2012
- Author(s)
  新家眞、北澤克明、山本哲也、澤田明、岩瀬愛子、山本精一郎、吉村健一、原英彰、嶋澤雅光、伊藤保志、山嶋哲盛、今村和幸、笹岡正顕、太田貴史、水野憲、川北耕二、大橋靖雄、白土城照、山崎芳夫、松本長太、玉置泰裕、相原一、富所敦男、永原幸、山上淳吉、古関信之、石井清、高山淳、長谷川智之、間山千尋、内田彩子、山田秀之、大橋正明、Yi-Ning Chen、佐伯忠賜朗、重枝崇史、村田博、Kelvin Lee、鶴我英和、Mao Nakayama、山岸麗子
- Journal Title
  
  日本眼科学会雑誌
  
  Volume: 115 Pages: 213-237
- NAID
  10029367236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] An alteration in the lateral geniculate nucleus of experimental glaucoma monkeys : In vivo positron emission tomography imaging of glialactivation2012
- Author(s)
  Shimazawa M., Ito Y., Inokuchi Y., Yamanaka H., Nakanishi T., Hayashi T., Ji B., Higuchi M., Suhara T., Imamura K., Araie M., Watanabe Y., Onoe H., Hara H.
- Journal Title
  
  PLoS ONE
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] Induction of amyloid-beta(1-42) in the retina and optic nerve head of chronic ocular hypertensive monkeys2012
- Author(s)
  Ito, Y., Shimazawa, M., Tsuruma, K., Mayama, C., Ishii, K., Onoe, H., Aihara, M., Araie, M., Hara, H
- Journal Title
  
  Mol Vis
  
  Volume: 18 Pages: 2647-2657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592612
[Journal Article] An Alteration in the Lateral Geniculate Nucleus of Experimental Glaucoma Monkeys : In vivo Positron Emission Tomography Imaging of Glial Activation2012
- Author(s)
  Shimazawa, M., Ito, Y., Inokuchi, Y., Yamanaka, H., Nakanishi, T., Hayashi, T., Ji, B., Higuchi, M., Suhara, T., Imamura, K., Araie, M., Watanabe, Y., Onoe, H., Hara, H.
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592612
[Journal Article] Involvement of endoplasmic reticulum stress in optic nerve degeneration following N-methyl-D-aspartate- induced retinal damage in mice2012
- Author(s)
  Shimazawa, M., Miwa, A., Ito, Y., Tsuruma, K., Aihara, M., Hara, H
- Journal Title
  
  J Neurosci Res
  
  Volume: 90 Pages: 1960-1969
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592612
[Journal Article] An alteration in the lateral geniculate nucleus of experimental glaucoma monkeys : In vivo positron emission tomography imaging of glial activation2012
- Author(s)
  Shimazawa M., Ito Y., Inokuchi Y., Yamanaka H., Nakanishi T., Hayashi T., Ji B., Higuchi M., Suhara T., Imamura K., Araie M., Watanabe Y., Onoe H. and Hara H.
- Journal Title
  
  PLoS ONE
  
  Volume: 7
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] An alteration in the lateral geniculate nucleus of experimental glaucoma monkeys: In vivo positoron emission tomography imaging of glial activation2012
- Author(s)
  Shimazawa M., Ito Y., Inokuchi Y., Yamanaka H., Hayashi T., Jin B., Higuchi M., Suhara T., Imamura K., Araie M., Watanabe Y., Onoe H., Hara H
- Journal Title
  
  PLoS one
  
  Volume: 7(1) Issue: 1 Pages: 1-14
- DOI
  10.1371/journal.pone.0030526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500311, KAKENHI-PLANNED-23111009, KAKENHI-PROJECT-23390235, KAKENHI-PROJECT-23592612
[Journal Article] 眼圧非依存障害因子への挑戦-ネズミ・サル・そしてヒトへ-2012
- Author(s)
  新家眞、北澤克明、山本哲也、澤田明、岩瀬愛子、山本精一郎、吉村健一、原英彰、嶋澤雅光、伊藤保志、山嶋哲盛、今村和幸、笹岡正顕、太田貴史、水野憲、川北耕二、大橋靖雄、白土城照、山崎芳夫、松本長太、玉置泰裕、相原一、富所敦男、永原幸、山上淳吉、古関信之、石井清、高山淳、長谷川智之、間山千尋、内田彩子、山田秀之、大橋正明、Yi-Ning Chen、佐伯忠賜朗、重枝崇史、村田博、Kelvin Lee、鶴我英和、Mao Nakayama、山岸麗子、緑内障
- Journal Title
  
  日本眼科学会雑誌
  
  Volume: 115 Pages: 213-237
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] SUN N8075, a novel radical scavenger, protects against retinal cell death in mice.2011
- Author(s)
  Masamitsu Shimazawa, Hideaki Hara
- Journal Title
  
  Neurosci.Lett.
  
  Volume: 488 Pages: 87-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592082
[Journal Article] PETを用いた緑内障早期診断法の確立2011
- Author(s)
  嶋澤雅光、原英彰
- Journal Title
  
  PETジャーナル
  
  Volume: 13 Pages: 10-11
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] Involvement ofendoplasmic reticulum stress onneuronal cell death in the lateralgeniculate nucleus in the monkeyglaucoma model.2011
- Author(s)
  Ito Y., Shimazawa M., Inokuchi Y.,Yamanaka H., Tsuruma K., Imamura K.,Onoe H., Watanabe Y., Aihara M., AraieM., Hara H.
- Journal Title
  
  European Journal of Neuroscience 33
  
  Pages: 843-855
- Data Source
  KAKENHI-PROJECT-20592082
[Journal Article] Involvement of endoplasmic reticulum stress on neuronal cell death in the lateral geniculate nucleus in the monkey glaucoma model2011
- Author(s)
  Ito Y., Shimazawa M., Inokuchi Y., Yamanaka H., Tsuruma K., Imamura K., Onoe H., Watanabe Y., Aihara M., Araie M. and Hara H.
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 33 Pages: 843-855
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] Involvement of endoplasmic reticulum stress on neuronal cell death in the lateral geniculate nucleus in the monkey glaucoma model2011
- Author(s)
  Masamitsu Shimazawa, Hideaki Hara
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 33 Pages: 843-855
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592082
[Journal Article] Crocetin prevents retinal degeneration induced by oxidative and endoplasmic reticulum stresses via inhibition of caspase activity2011
- Author(s)
  Yamauchi, M., Tsuruma, K., Imai, S/,Nakanishi, T., Umigai, N., Shimazawa, M., Hara, H.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 650 Pages: 110-119
- Data Source
  KAKENHI-PROJECT-23592612
[Journal Article] SUN N8075, anovel radical scavenger, protectsagainst retinal cell death in mice.2011
- Author(s)
  Akane M., Shimazawa M., Inokuchi Y.,Tsuruma K., Hara H.
- Journal Title
  
  Neurosci. Lett 488
  
  Pages: 87-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592082
[Journal Article] A novel calpaininhibitor,((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester (SNJ-1945),reduces murine retinal cell death invitro and in vivo.2010
- Author(s)
  Shimazawa M., Suemori S., Inokuchi Y.,Matsunaga N., Nakajima Y., Oka T.,Yamamoto T., Hara H.
- Journal Title
  
  J. Pharmacol. Exp.Ther 332
  
  Pages: 380-387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592082
[Journal Article] Lomerizine. Ca^<2->-channel blocker, protects against neuronal degeneration within the visual center of the brain after retinal damage in mice2010
- Author(s)
  Ito Y., Nakamura S., Tanaka H., Tsuruma K., Shimazawa M., Araie M., Hara H.
- Journal Title
  
  CNS Neuroscience and Therapeutics 16
  
  Pages: 103-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] Lomerizine, Ca^<2+>-channel blocker, protects against neuronal degeneration within the visual center of the brain after retinal damage in mice2010
- Author(s)
  Ito Y., Nakamura S., Tanaka H., Tsuruma K., Shimazawa M., Araie M. and Hara H.
- Journal Title
  
  CNS Neuroscience and Therapeutics
  
  Volume: 16 Pages: 103-114
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] An inducer of VGF protectscells from ER stress-induced celldeath and prolongs survival in the mutant SOD1 animal models of familial ALS.2010
- Author(s)
  Shimazawa M., Tanaka H., Ito Y.,Morimoto N., Tsuruma K., Kadokura M.,Tamura S., Inoue Y., Yamada M.,Takahashi H., Warita H., Aoki M., Hara H.
- Journal Title
  
  PLoS ONE, 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592082
[Journal Article] A Novel Calpain Inhibitor, ((1S)-1-((((1S)-1-Benzyl-3-cyclopropylamino-2, 3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic Acid 5-Methoxy-3-oxapentyl Ester(SNJ-1945), Reduces Murine Retinal Cell Death in Vitro and in Vivo2010
- Author(s)
  Masamitsu Shimazawa
- Journal Title
  
  J.Pharmacol.Exp.Ther 332
  
  Pages: 380-387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592082
[Journal Article] An inducer of VGF protects cells from ER stress-induced cell death and prolongs survival in the mutant SOD1 animal models of familial ALS.2010
- Author(s)
  Masamitsu Shimazawa, Hideaki Hara
- Journal Title
  
  PLoS ONE
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592082
[Journal Article] Proliferative diabetic retinopathy and relations among antioxidant activity, oxidative stress, and VEGF in the vitreous body.2010
- Author(s)
  Izuta H, Shimazawa M, Sugiyama T, et al
- Journal Title
  
  Mol Vis.
  
  Volume: 16 Pages: 130-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591972
[Journal Article] Morphological changes in the visual pathway induced by experimental glaucoma in Japanese monkeys.2009
- Author(s)
  Ito Y., Shimazawa M., Chen Y. N., Tsuruma K., Yatnashita T., Araie M., Hara H.
- Journal Title
  
  Exp. Eye Res. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592031
[Journal Article] Involvement of brain-derived neurotrophic factor in time-dependent neurodegeneration in the murine superior colliculus after intravitreal injection of N-methyl-D-aspartate2009
- Author(s)
  Tanaka H., Ito Y., Nakamura S., Shimazawa M. and Hara H.
- Journal Title
  
  Mol. Vision
  
  Pages: 662-669
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] Molecular imaging reveals unique degenerative changes in experimental glaucoma.2009
- Author(s)
  Imamura K., Onoe H., Shimazawa M., Nozaki S., Wada Y., K ato K., Nakajima H., Mizuma H., Onoe K., Taniguchi T., Sasaoka M., Hara H., Tanaka S., Araie M., Watanabe Y.
- Journal Title
  
  NeuroReport 20
  
  Pages: 139-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592031
[Journal Article] nvolvement of brain-derived neurotrophic factor in time-dependent neurodegeneration in the murine superior colliculus after intiavitreal injection of N-methyl-D-aspartate2009
- Author(s)
  Tanaka H., Ito Y., Nakamura S., Shimazawa M., Hara H.
- Journal Title
  
  Mol. Vision 15
  
  Pages: 662-669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] Changes in visual fields and lateral geniculate nucleus in monkey laser-induced high intraocular pressure model2008
- Author(s)
  Sasaoka M., Nakamura K., Shimazawa M., Ito Y., Araie M. and Hara H.
- Journal Title
  
  Exp. Eye Res 86
  
  Pages: 770-782
- Data Source
  KAKENHI-PROJECT-19592031
[Journal Article] Changes in visual fields and lateral geniculate nucleus in monkey laser-induced high intraocular pressure model.2008
- Author(s)
  Sasaoka M., Nakamura K., Shimazawa M., Ito Y., Araie M., Hara H.
- Journal Title
  
  Exp. Eye Res. 86
  
  Pages: 770-782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592031
[Journal Article] アミロイドβ蛋白質の網膜機能および細胞死に対する影響2007
- Author(s)
  嶋澤雅光
- Journal Title
  
  日本眼科学会雑誌 111
  
  Pages: 982-982
- Data Source
  KAKENHI-PROJECT-18659515
[Journal Article] Morphometric evaluation of changes with time in optic disc structure and thickness of retinal nerve fibre layer in chronic ocular hypertensive monkeys.2006
- Author(s)
  Shimazawa M., Tomita G., Taniguchi T., Sasaoka M., Hara H., Kitazawa Y., Araie M.
- Journal Title
  
  Exp. Eye Res. 82
  
  Pages: 427-440
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591848
[Journal Article] Nerve fiber layer measurement using scanning laser polarimetry with fixed corneal compensator in normal cycnomolgus monkey eyes.2006
- Author(s)
  Shimazawa M., Taniguchi T., Sasaoka M., Hara H.
- Journal Title
  
  Ophthalmic Res. 38
  
  Pages: 1-7
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591848
[Journal Article] Nerve fiber layer measurement using scanning laser polarimetry with fixed corneal compensator in normal cycnomolgus monkey eyes.2006
- Author(s)
  Shimazawa M., Taniguchi T., Sasaoka M., Hara H.
- Journal Title
  
  Ophthanlmic Res. 38
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-17591848
[Journal Article] Morphometric evaluation of changes with time in optic disc structure and thickness of retinal nerve fibre layer in chronic ocular hypertensive monkeys.2006
- Author(s)
  Shimazawa M., Tomita G., Taniguchi T., Sasaoka M., Hara H., Kitazawa Y., Araie M.
- Journal Title
  
  Exp.Eye Res. 82
  
  Pages: 427-440
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591848
[Journal Article] Optic disc topographic parameters, measured in the normal cynomolgus monkey by confocal scanning laser tomography.2005
- Author(s)
  Taniguchi T., Shimazawa M., Araie M., Tomita G., Sasaoka M., Kitazawa Y., Hara H.
- Journal Title
  
  Br.J.Ophthalmol. 89
  
  Pages: 1058-1062
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591848
[Journal Article] Optic disc topographic parameters measured in the normal cynomolgus monkey by confocal scanning laser tomography.2005
- Author(s)
  Taniguchi T., Shimazawa M., Araie M., Tomita G., Sasaoka M., Kitazawa Y., Hara H.
- Journal Title
  
  Br. J. Ophthalmol. 89
  
  Pages: 1058-1062
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591848
[Journal Article] Morphological changes in the visual pathway induced by experimental glaucoma in Japanese monkeys
- Author(s)
  Ito Y., Shimazawa M., Chen Y. N., Tsuruma K., Yamashita T., Araie M. and Hara H.
- Journal Title
  
  Exp. Eye Res (in press)
- Data Source
  KAKENHI-PROJECT-19592031
[Journal Article] Involvement of Bid and caspase-2 inendoplasmic reticulum stress- andoxidative stress-induced retinalganglion cell death.
- Author(s)
  Uchibayashi R., Tsuruma K., Inokuchi Y., Shimazawa M., Hara H.
- Journal Title
  
  J. Neurosci. Res in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] 生体組織イメージングを指向したヘム駆動型生体分子修飾化剤の開発2023
- Author(s)
  垣内亮、平山祐、辻翔平、嶋澤雅光、田村朋則、浜地格、辻美恵子、永澤秀子
- Organizer
  第40回メディシナルケミストリーシンポジウム2023
- Data Source
  KAKENHI-PROJECT-23K23490
[Presentation] 実験的緑内障モデルを用いた網膜・視路変性における病態関連分子の探索2023
- Author(s)
  嶋澤雅光
- Organizer
  第127回日本眼科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09793
[Presentation] Development of a new heme-selective fluorescent probe for sensing subcellular dynamics of labile heme2023
- Author(s)
  Ryo Kakiuchi, Tasuku Hirayama, Shohei Tsuji, Masamitsu Shimazawa, Tomonori Tamura, Itaru Hamachi, Mieko Tsuji, Hideko Nagasawa
- Organizer
  BIORON2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23490
[Presentation] 網膜疾患の病態解明とアカデミア創薬への挑戦2022
- Author(s)
  嶋澤雅光
- Organizer
  第42回日本眼薬理学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09793
[Presentation] 実験的網膜疾患モデルを用いた病態解明と創薬ターゲットの探索2022
- Author(s)
  嶋澤雅光
- Organizer
  第49回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09793
[Presentation] Development of heme-selective biomolecule-labeling probes for omics analysis and tissue imaging2022
- Author(s)
  R. Kakiuchi, T. Hirayama, S. Tsuji, M. Shimazawa, T. Tamura, I. Hamachi, M. Tsuji, H. Nagasawa
- Organizer
  The 8th International Symposium on Metallomics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23490
[Presentation] オミクス解析と組織イメージングを指向したヘム選択的生体分子修飾化剤の開発2022
- Author(s)
  垣内　亮、平山　祐、辻　翔平、嶋澤　雅光、田村　朋則、浜地　格、辻　美恵子、永澤　秀子
- Organizer
  日本ケミカルバイオロジー学会第16回年会
- Data Source
  KAKENHI-PROJECT-23K23490
[Presentation] 緑内障患者iPS細胞より分化誘導した網膜細胞を利用した緑内障の病態解明2018
- Author(s)
  嶋澤　雅光
- Organizer
  第91回日本生化学大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K11486
[Presentation] The effect of VGF nerve growth factor inducible on retinal ganglion cell injury after optic nerve crush in mice.2018
- Author(s)
  Masamitsu Shimazawa
- Organizer
  ARVO 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11486
[Presentation] Movement of retinal vessels toward the optic nerve head after increasing intraocular pressure in monkey eyes with experimental glaucoma2017
- Author(s)
  Kuroda A, Enomoto N, Ishida K, Shimazawa M, Noguchi T, Horai N, Onoe H, Hara H, Tomita G
- Organizer
  World Glaucoma Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462634
[Presentation] 緑内障の神経保護治療への研究アプローチ2017
- Author(s)
  嶋澤雅光
- Organizer
  第37回日本眼薬理学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K11486
[Presentation] VGF overexpression mice show psychological abnormal behaviors.2016
- Author(s)
  溝口貴洋、石坂光絵、鶴間一寛、嶋澤雅光、原英彰
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26462694
[Presentation] Evaluation of bleb characteristics after trabeculectomy, Ex-Press implantation, and tube shunt surgery2016
- Author(s)
  Ishida K, Nakano Y, Ojino K, Shimazawa M, Otsuka T, Kawase K, Hara H, Yamamoto T
- Organizer
  Eupropean Glaucoma Society Congress
- Place of Presentation
  プラハ（チェコ）
- Year and Date
  2016-06-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462634
[Presentation] サル眼実験緑内障モデルにおける眼圧上昇後の視神経乳頭周囲の血管移動2016
- Author(s)
  黒田敦美、榎本暢子、石田恭子、嶋澤雅光、野口哲郎、賀來直人、原英彰、富田剛司
- Organizer
  第27回日本緑内障学会
- Place of Presentation
  パシフィコ横浜(神奈川県、横浜市)
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-26462634
[Presentation] 視神経挫滅モデルにおけるVGF nerve growth factor inducibleの神経保護作用2016
- Author(s)
  竹内寛人、中野志迪、射和寛、久世祥己、鶴間一寛、嶋澤雅光、原英彰
- Organizer
  第36回日本眼薬理学会
- Place of Presentation
  東京
- Year and Date
  2016-09-10
- Data Source
  KAKENHI-PROJECT-26462694
[Presentation] 網膜疾患における小胞体ストレスの関与と新規治療戦略2012
- Author(s)
  嶋澤雅光、原英彰
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] 緑内障の病態解明と神経保護をターゲットとした薬物治療の現状と将来展望2012
- Author(s)
  嶋澤　雅光、原　英彰
- Organizer
  第32回日本眼薬理学会
- Place of Presentation
  ピアザ淡海
- Invited
- Data Source
  KAKENHI-PROJECT-23592612
[Presentation] 緑内障の病態解明と神経保護をターゲットとした薬物治療の現状と将来展望2012
- Author(s)
  嶋澤雅光、原英彰
- Organizer
  第32回日本眼薬理学会
- Place of Presentation
  大津
- Invited
- Data Source
  KAKENHI-PROJECT-23592612
[Presentation] 網膜・視神経障害に伴う視路変性およびその治療戦略2011
- Author(s)
  嶋澤雅光、原英彰
- Organizer
  第54回日本神経化学大会
- Place of Presentation
  金沢
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] 緑内障性視神経症と神経変性疾患の関連2011
- Author(s)
  嶋澤雅光、鶴間一寛、原英彰
- Organizer
  第115回日本眼科学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] NMDA誘発視神経障害における小胞体ストレスの関与2011
- Author(s)
  三輪彰範、伊藤保志、鶴間一寛、嶋澤雅光、原英彰
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] PETおよびMRIを用いた緑内障モデルサルにおける分子脳イメージング2011
- Author(s)
  原英彰、嶋澤雅光
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] 網膜・視神経障害に伴う視路変性およびその治療戦略2011
- Author(s)
  嶋澤雅光、原英彰
- Organizer
  第54回日本神経化学大会
- Place of Presentation
  金沢、加賀
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] 緑内障性視神経症と神経変性疾患の関連2011
- Author(s)
  嶋澤雅光、鶴間一寛、原英彰
- Organizer
  第115回日本眼科学会総会
- Place of Presentation
  東京
- Year and Date
  2011-05-12
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] PETを用いた緑内障早期診断法の確立2011
- Author(s)
  嶋澤雅光
- Organizer
  第5回日本分子イメージング学会学術集会
- Place of Presentation
  ピアザ淡海(滋賀県)
- Year and Date
  2011-05-22
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] サルPET及びMRIを用いたレーザー照射誘発高眼圧後の脳のイメージング2010
- Author(s)
  嶋澤雅光
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2010-03-23
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] The effect of SUN N8075 on endoplasmic reticulumstress-induced cell death in RGC-5 cells.2010
- Author(s)
  嶋澤雅光, 内林瑠美, 鶴間一寛, 原英彰
- Organizer
  ARVO 2010 Annual Meeting
- Place of Presentation
  FortLauderdale, Florida
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] Involvement ofendoplasmic reticulum stress onneuronal degeneration in the lateralgeniculate nucleus in the monkeyglaucoma model.2010
- Author(s)
  Ito Y., Shimazawa M., Inokuchi Y., Miwa A., Yamanaka H., Tsuruma K., Onoe H., Araie M., Hara H.
- Organizer
  ARVO 2010 AnnualMeeting
- Place of Presentation
  Fort Lauderdale, Florida
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] The effect of SUN N8075 on endoplasmic reticulum stress-induced death in RGC-5 cells2010
- Author(s)
  Masamitsu Shimazawa
- Organizer
  ARVO2010
- Place of Presentation
  Convention Center (Fort Lauderdale, Florida)
- Year and Date
  2010-05-06
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] 分子イメージングを用いた緑内障早期診断及び創薬研究2010
- Author(s)
  嶋澤雅光
- Organizer
  第2回異分野交流研究会
- Place of Presentation
  岐阜薬科大学(岐阜市)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] In vitro およびin vivo 網膜神経節細胞死に対する新規カルパイン阻害剤 SNJ-1945 の作用2009
- Author(s)
  嶋澤雅光、末森晋典、井口勇太、松永望、中島佳美、岡隆之、山本哲也、原英彰
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] 網膜神経節細胞死に対する SUN N8075 の保護作用2009
- Author(s)
  内林瑠美、嶋澤雅光、鶴間一寛、原英彰
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] 網膜神経節細胞死におけるBid およびCaspase 2 の関与2009
- Author(s)
  内林瑠美、井口勇太、嶋澤雅光、鶴間一寛、原英彰
- Organizer
  第116 回日本薬理学会近畿部会
- Place of Presentation
  大津
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] Protectiveeffect of SUN N8075 on endoplasmicreticulum stress-induced cell death in SH-SY5Y cells.2008
- Author(s)
  嶋澤雅光, 原英彰
- Organizer
  Neuroscience 2008
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] 小胞体ストレス誘発網膜神経節細胞死に対するSUN N8075 の作用2008
- Author(s)
  嶋澤雅光、内林瑠美、原英彰
- Organizer
  第28回日本眼薬理学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] 網膜障害誘発外側膝状体(LGN)の形態的・経時的変化2008
- Author(s)
  伊藤保志、嶋澤雅光、陳逸寧、山嶋哲盛、新家眞、原英彰
- Organizer
  第12回視覚科学フォーラム
- Place of Presentation
  豊中
- Data Source
  KAKENHI-PROJECT-19592031
[Presentation] 小胞体ストレス誘発網膜神経節細胞死に対するSUN N8075の作用2008
- Author(s)
  嶋澤雅光
- Organizer
  第28回日本眼薬理学会
- Place of Presentation
  ホテルグランヴィア岡山
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] アミロイドβ蛋白質の網膜機能および細胞死に対する影響2007
- Author(s)
  嶋澤雅光
- Organizer
  第27回日本眼薬理学会
- Place of Presentation
  岐阜長良国際会議場
- Year and Date
  2007-09-16
- Data Source
  KAKENHI-PROJECT-18659515
[Presentation] Involvement of amyloid-β in retinal function2007
- Author(s)
  嶋澤雅光
- Organizer
  The Association for Research in Vision and Ophthalmology(ARVO 2007)
- Place of Presentation
  フォートローダデール(アメリカ合衆国)
- Year and Date
  2007-05-07
- Data Source
  KAKENHI-PROJECT-18659515

1. HARA Hideaki (20381717)

# of Collaborated Projects: 11 results

# of Collaborated Products: 61 results
2. ARAIE Makoto (00092122)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. WATANABE Yasuyoshi (40144399)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
4. SUGIYAMA Tetsuya (20298764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. IKEDA Tsunehiko (70222891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OKU Hidehiro (90177163)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KOJIMA Shota (10388259)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAKAI Shinji (80288703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KURIMOTO Takuji (50388815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ISHIDA Kyoko (80334936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. IMAMURA Kazuyuki (30203326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 村田一弘 (10585912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 川瀬和秀 (40234067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 山本哲也 (50134581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 中村信介 (80815613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 平山祐 (10600207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. SASAOKA Masaaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
18. NAKAMURA Katsuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 新家真

# of Collaborated Projects: 0 results

# of Collaborated Products: 19 results

SHIMAZAWA Masamitsu 嶋澤 雅光

Research Projects

Research Products

Co-Researchers

滲出型加齢黄斑変性の線維化病変に発現する新規ncRNAの機能解析

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Chemical-tool-driven research on heme dynamics

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Review Section

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Discovery of pathogenesis-related biomarkers from blood exosome analysis in glaucomatous optic neuropathyPrincipal Investigator

Principal Investigator

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Review Section

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Development of therapeutic drugs targeting VGF-modifying peptides in retinal diseasesPrincipal Investigator

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Structural and morphorogical changes after glaucoma surgery

Principal Investigator

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A study for protective mechanisms of VGF, a neurosecretory peptide, in glaucomatous optic nerve degenerationPrincipal Investigator

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A study for protective mechanisms of VGF, a neurosecretory peptide, in retinal injuryPrincipal Investigator

Principal Investigator

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Involvement of activated P2X7 receptor in disorder of retinal ganglion cells in animal models of glaucoma

Principal Investigator

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Morphological and functional changes in visual cortex after retinal damage and its pharmacological approach

Principal Investigator

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A study of molecular mechanisms of endoplasmic reticulum stress in retinal ganglion cell deathPrincipal Investigator

Principal Investigator

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Changes in visual fields and retinal function in high intraocular pressure model of monkeys

Principal Investigator

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Research Institution

緑内障及び糖尻病網膜症の病態におけるアルツハイマー病の関連性についてPrincipal Investigator

Principal Investigator

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Research Institution

Functional changes mediated by high-intraocular pressure-induced optic nerve damage in lateral geniculate body and visual cortex of monkeys.

Principal Investigator

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SHIMAZAWA Masamitsu 嶋澤雅光