HANAI Nobuhiro 花井信広

… Alternative Names

花井信広ハナイノブヒロ

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Researcher Number	80381797
Other IDs
Affiliation (Current)	2025: 愛知県がんセンター(研究所), がん予防研究分野, 研究員
Affiliation (based on the past Project Information) *help	2018 – 2023: 愛知県がんセンター(研究所), がん予防研究分野, 研究員 2017: 愛知県がんセンター(研究所), 遺伝子医療研究部, 研究員 2015 – 2017: 愛知県がんセンター(研究所), その他部局等, その他 2016: 愛知県がんセンター(研究所), 腫瘍医化学部, 研究員 2007 – 2008: Aichi Cancer Center Research Institute, 発がん制御研究部, 研究員 2005 – 2006: 名古屋市立大学, 大学院医学研究科, 助手
Review Section/Research Field	Principal Investigator Otorhinolaryngology Except Principal Investigator Basic Section 49020:Human pathology-related / Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology
Keywords	Principal Investigator 頭頸部癌 / 頭頸部外科学 / 頸部リンパ節転移 / 化学放射線療法 / 超音波検査 / MTTアッセイ / リアルタイムPCR / 5-FU / TS-1 / 感受性試験 … More / オーダーメイド治療 / 頭頸部がん / 頭頸部外科 / 薬剤反応性 / タンパク質 / 癌 / 遺伝子 … More Except Principal Investigator 個別化治療 / 唾液腺癌 / 粘表皮癌 / 腺様嚢胞癌 / 唾液腺腫瘍 / 頭頸部癌 / がん抗原 / バイオマーカー / 好酸球 / 免疫チェックポイント阻害薬 / 分子標的薬 / キメラ遺伝子 / 分子病態 / 臨床病理学 / 分子病理学的研究 / 多施設共同研究 / 頸部郭清 / 頭頸部がん / リンパ節転移 / 病理診断 / データベース / 頸部リンパ節転移 / 診断基準 / 偽陽性 / 厚み / 多施設研究 / 頸部rンパ説転移 / 扁平上皮癌 / 超音波診断 Less

Molecular pathological analysis of salivary gland carcinomas promoting personalized medicine: A large-scale multicenter study
- Principal Investigator
  
  Inagaki Hiroshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Nagoya City University
簡易モニタリングのための好酸球を用いた頭頸部がん免疫治療バイオマーカーの開発
- Principal Investigator
  
  西川大輔
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Aichi Cancer Center Research Institute
Molecular pathological analysis of salivary gland carcinomas focusing on personalized medicine: A large-scale multicenter study
- Principal Investigator
  
  Inagaki Hiroshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Nagoya City University
Examination about US diagnosis of cervical lymph node after chemoradiotherapyPrincipal Investigator
- Principal Investigator
  
  HANAI Nobuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Aichi Cancer Center Research Institute
Multicenter Trial on the Ultrasound Diagnostic Criteria of Cervical Lymph Node Metastasis from Head and Neck Cancer
- Principal Investigator
  
  Furukawa Madoka
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kanagawa Cancer Center Research Institute
Customizing Adjuvant Chemotherapy in Head and Neck CancerPrincipal Investigator
- Principal Investigator
  
  HANAI Nobuhiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Aichi Cancer Center Research Institute
頭頚部癌におけるAuroraキナーゼ発現の検討Principal Investigator
- Principal Investigator
  
  花井信広
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagoya City University

All 2023 2021 2020 2019 2018 2017 2016 2009 2008 2007

All Journal Article Presentation

[Journal Article] The Landscape of MYB/MYBL1- and Peri-MYB/MYBL1-Associated Rearrangements in Adenoid Cystic Carcinoma2023
- Author(s)
  Ueda Kaori, Murase Takayuki, Inagaki Hiroshi
- Journal Title
  
  Modern Pathology
  
  Volume: 36 Issue: 10 Pages: 100274-100274
- DOI
  10.1016/j.modpat.2023.100274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15388, KAKENHI-PROJECT-22K06939, KAKENHI-PROJECT-23K06432, KAKENHI-PROJECT-23K06469, KAKENHI-PROJECT-21H02704
[Journal Article] Prognostic scores for patients with salivary adenoid cystic carcinoma without lymph node metastasis2023
- Author(s)
  Shimoda H, Teshima M, Murase T, Nagao T, Kusafuka K, Nakaguro M, Urano M, Taguchi KI, Yamamoto H, Kano S, Tada Y, Tsukahara K, Okami K, Onitsuka T, Fujimoto Y, Kawakita D, Sakurai K, Hanai N, Nagao T, Kawata R, Hato N, Nibu KI, Inagaki H.
- Journal Title
  
  Oral Oncology
  
  Volume: 145 Pages: 106491-106491
- DOI
  10.1016/j.oraloncology.2023.106491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06939, KAKENHI-PROJECT-23K06432, KAKENHI-PROJECT-23K06469, KAKENHI-PROJECT-21H02704
[Journal Article] Salivary mucoepidermoid carcinoma: histological variants, grading systems, CRTC1/3-MAML2 fusions, and clinicopathological features2021
- Author(s)
  Nakano Satsuki、Okumura Yoshihide、Murase Takayuki、Nagao Toshitaka、Kusafuka Kimihide、Urano Makoto、Yamamoto Hidetaka、Kano Satoshi、Tsukahara Kiyoaki、Okami Kenji、Kawakita Daisuke、Nagao Toru、Hanai Nobuhiro、Iwai Hiroshi、Kawata Ryo、Tada Yuichiro、Nibu Ken‐Ichi、Inagaki Hiroshi
- Journal Title
  
  Histopathology
  
  Volume: 80 Issue: 4 Pages: 729-735
- DOI
  10.1111/his.14586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02704, KAKENHI-PROJECT-20K10508, KAKENHI-PROJECT-21K06891, KAKENHI-PROJECT-21K09641
[Journal Article] Pathological evaluation of tumor grade for salivary adenoid cystic carcinoma: A proposal of an objective grading system2021
- Author(s)
  Morita N, Murase T, Ueda K, Nagao T, Kusafuka K, Nakaguro M, Urano M, Taguchi KI, Yamamoto H, Kano S, Tada Y, Tsukahara K, Okami K, Onitsuka T, Fujimoto Y, Kawakita D, Sakurai K, Nagao T, Hanai N, Kawata R, Hato N, Otsuki N, Nibu KI, Inagaki H.
- Journal Title
  
  Cancer Science
  
  Volume: 112(3) Issue: 3 Pages: 1184-1195
- DOI
  10.1111/cas.14790
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10508, KAKENHI-PROJECT-18H02633, KAKENHI-PROJECT-19H03804, KAKENHI-PROJECT-21H02704, KAKENHI-PROJECT-20K07417, KAKENHI-PROJECT-21K15388
[Journal Article] The impact of clinicopathological factors on clinical outcomes in patients with salivary gland adenoid cystic carcinoma: a multi-institutional analysis in Japan2020
- Author(s)
  Kawakita D, Murase T, Ueda K, Kano S, Tada Y, Tsukahara K, Okami K, Onitsuka T, Fujimoto Y, Matoba T, Sakurai K, Nagao T, Hanai N, Kawata R, Hato N, Nibu KI, Urano M, Taguchi KI, Nakaguro M, Kusafuka K, Yamamoto H, Nagao T, Inagaki H.
- Journal Title
  
  International Journal of Cinical Oncology
  
  Volume: 25(10) Issue: 10 Pages: 1774-1785
- DOI
  10.1007/s10147-020-01731-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10508, KAKENHI-PROJECT-19K18779, KAKENHI-PROJECT-19KK0202, KAKENHI-PROJECT-18H02633, KAKENHI-PROJECT-20K07417
[Journal Article] Prognostic impact of CRTC1/3-MAML2 fusions in salivary gland mucoepidermoid carcinoma: A multiinstitutional retrospective study2020
- Author(s)
  Okumura Y, Nakano S, Murase T, Ueda K, Kawakita D, Nagao T, Kusafuka K, Urano M, Yamamoto H, Kano S, Tsukahara K, Okami K, Nagao T, Hanai N, Iwai H, Kawata R, Tada Y, Nibu KI, Inagaki H.
- Journal Title
  
  Cancer Science
  
  Volume: 111(11) Issue: 11 Pages: 4195-4204
- DOI
  10.1111/cas.14632
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10508, KAKENHI-PROJECT-18H02633, KAKENHI-PROJECT-20K07417
[Journal Article] Central pathology review of salivary gland adenoid cystic carcinoma2020
- Author(s)
  Ueda K、Murase T、Nagao T、Kusafuka K、Urano M、Yamamoto H、Nakaguro M、Taguchi K、Masaki A、Hirai H、Kawakita D、Tsukahara K、Hato N、Nagao T、Fujimoto Y、Sakurai K、Hanai N、Kano S、Onitsuka T、Okami K、Nibu K、Tada Y、Kawata R、Inagaki H
- Journal Title
  
  Head & Neck
  
  Volume: X Issue: 8 Pages: 1721-1727
- DOI
  10.1002/hed.26081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09386, KAKENHI-PROJECT-18K16095, KAKENHI-PROJECT-19K16568, KAKENHI-PROJECT-17K08705, KAKENHI-PROJECT-20K10508, KAKENHI-PROJECT-18H02633, KAKENHI-PROJECT-20K07417
[Journal Article] Mutation analysis of the EGFR pathway genes, EGFR, RAS, PIK3CA, BRAF, and AKT1, in salivary gland adenoid cystic carcinoma.2018
- Author(s)
  Saida K, Murase T, Ito M, Fujii K, Takino H, Masaki A, Kawakita D, Ijichi K, Tada Y, Kusafuka K,Iida Y, Onitsuka T, Yatabe Y, Hanai N, Hasegawa Y
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 24 Pages: 17043-17055
- DOI
  10.18632/oncotarget.24818
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11247, KAKENHI-PROJECT-17K15647, KAKENHI-PROJECT-17K18006, KAKENHI-PROJECT-15K08351, KAKENHI-PROJECT-16H05481, KAKENHI-PROJECT-17K08746, KAKENHI-PROJECT-16H05167, KAKENHI-PROJECT-18H02633
[Journal Article] 【頭頸部悪性腫瘍の疑問に答える】手術手技頸部郭清術の術前プランニングの実際について教えてください2017
- Author(s)
  花井信広
- Journal Title
  
  JOHNS
  
  Volume: 33 Pages: 1276-1278
- Data Source
  KAKENHI-PROJECT-16K11254
[Journal Article] 頭頸部癌治療効果判定2016
- Author(s)
  寺田星乃、花井信広
- Journal Title
  
  JOHNS
  
  Volume: 32 Pages: 1494-1497
- Data Source
  KAKENHI-PROJECT-16K11254
[Journal Article] 頭頸部扁平上皮癌に対するDocetaxelとCisplatin併用化学療法の第II相試験2009
- Author(s)
  花井信広, ほか
- Journal Title
  
  癌と化学療法36 (掲載予定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791222
[Journal Article] 頭頸部扁平上皮癌に対するDocetaxelとCisplatin併用化学療法の第II相試験2009
- Author(s)
  花井信広ほか
- Journal Title
  
  癌と化学療法 36(掲載予定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791222
[Journal Article] Prediction of chemosensitivity using multigene analysis in head and neck squamous cell carcinoma.2007
- Author(s)
  Hasegawa Y, Goto M, Hanai N, et al.
- Journal Title
  
  Oncology 73(1-2)
  
  Pages: 104-111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791222
[Presentation] 全身麻酔下の二期的シャント造設 ―福原法変法の有用性―2019
- Author(s)
  花井信広，別府慎太郎，西川大祐，寺田星乃
- Organizer
  第34回西日本音声外科研究会
- Data Source
  KAKENHI-PROJECT-16K11254
[Presentation] 化学放射線治療による喉頭温存2019
- Author(s)
  花井信広
- Organizer
  第42回日本喉頭科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-16K11254
[Presentation] エビデンスに基づいた頭頸部癌の治療戦略2018
- Author(s)
  花井信広
- Organizer
  第119回日本耳鼻咽喉科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11254
[Presentation] The utility of ultrasound in the diagnosis of cervical lymph nodes after chemoradiotherapy2017
- Author(s)
  N.Hanai, H.Terada, Y.Shimode et al
- Organizer
  第37回日本乳腺甲状腺超音波医学会学術集会
- Place of Presentation
  バリ国際コンベンションセンター（バリ）
- Year and Date
  2017-03-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11254
[Presentation] 表在リンパ節の超音波診断リンパ節の計測法に関する問題点2017
- Author(s)
  花井信広、寺田星乃、長谷川泰久
- Organizer
  日本超音波医学会第90回学術集会・日本乳腺甲状腺超音波医学会第38回総会
- Data Source
  KAKENHI-PROJECT-16K11254
[Presentation] 甲状腺乳頭癌と頭頸部扁平上皮癌のリンパ節転移様式の違い2017
- Author(s)
  花井信広，寺田星乃，長谷川泰久
- Organizer
  第39回乳腺甲状腺超音波医学会学術集会
- Data Source
  KAKENHI-PROJECT-16K11254
[Presentation] Examination about US diagnosis of cervical lymph node after chemoradiotherapy2016
- Author(s)
  花井信広、寺田星乃、長谷川泰久
- Organizer
  第37回日本乳腺甲状腺超音波医学会学術集会
- Place of Presentation
  ウエスタ川越（川越市）
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-16K11254
[Presentation] Response evaluation after chemoradiotherapy for node-positive head and neck cancer using ultrasonography2016
- Author(s)
  寺田星乃、花井信広、長谷川泰久
- Organizer
  第37回日本乳腺甲状腺超音波医学会学術集会
- Place of Presentation
  ウエスタ川越（川越市）
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-16K11254
[Presentation] 頭頸部扁平上皮癌に対するDocetaxelとCisplatin併用化学療法の第II相試験2008
- Author(s)
  花井信広
- Organizer
  第25回東海頭頸部腫瘍研究会
- Place of Presentation
  名古屋
- Year and Date
  2008-01-24
- Data Source
  KAKENHI-PROJECT-19791222

1. Furukawa Madoka (10511793)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. Inagaki Hiroshi (30232507)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. 藤本保志 (40344337)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 門田伸也 (40501846)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 下出祐造 (60319043)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 松浦一登 (70271947)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 加納里志 (00374421)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. 中黒匡人 (00718356)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 奥村嘉英 (00792483)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. 岩井大 (10232638)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. 丹生健一 (20251283)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 草深公秀 (20368228)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 櫻井一生 (30178610)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 山元英崇 (30404073)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
15. 河田了 (40224787)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
16. 村瀬貴幸 (40315875)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
17. 田口健一 (40325527)

# of Collaborated Projects: 2 results

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18. 正木彩子 (40648044)

# of Collaborated Projects: 2 results

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19. 羽藤直人 (60284410)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. 多田雄一郎 (70292430)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
21. 川北大介 (70584506)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
22. 大上研二 (90223734)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
23. 長尾徹 (90261007)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
24. 長尾俊孝 (90276709)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
25. 内藤健晴 (10172248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 西川大輔 (30750731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 松下博和 (80597782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 二見淳一郎 (00420498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 澤部倫 (30790711)

# of Collaborated Projects: 1 results

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30. Furukawa Masaki

# of Collaborated Projects: 1 results

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31. HASEGAWA Yasuhisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 舟生健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 浦野誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 平井秀明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HANAI Nobuhiro 花井 信広

花井 信広 ハナイ ノブヒロ

Research Projects

Research Products

Co-Researchers

Molecular pathological analysis of salivary gland carcinomas promoting personalized medicine: A large-scale multicenter study

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

簡易モニタリングのための好酸球を用いた頭頸部がん免疫治療バイオマーカーの開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular pathological analysis of salivary gland carcinomas focusing on personalized medicine: A large-scale multicenter study

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Examination about US diagnosis of cervical lymph node after chemoradiotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Multicenter Trial on the Ultrasound Diagnostic Criteria of Cervical Lymph Node Metastasis from Head and Neck Cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Customizing Adjuvant Chemotherapy in Head and Neck CancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

頭頚部癌におけるAuroraキナーゼ発現の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The Landscape of MYB/MYBL1- and Peri-MYB/MYBL1-Associated Rearrangements in Adenoid Cystic Carcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic scores for patients with salivary adenoid cystic carcinoma without lymph node metastasis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Salivary mucoepidermoid carcinoma: histological variants, grading systems, CRTC1/3-MAML2 fusions, and clinicopathological features2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathological evaluation of tumor grade for salivary adenoid cystic carcinoma: A proposal of an objective grading system2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The impact of clinicopathological factors on clinical outcomes in patients with salivary gland adenoid cystic carcinoma: a multi-institutional analysis in Japan2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic impact of CRTC1/3-MAML2 fusions in salivary gland mucoepidermoid carcinoma: A multiinstitutional retrospective study2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Central pathology review of salivary gland adenoid cystic carcinoma2020

Author(s)

Journal Title

HANAI Nobuhiro 花井信広

花井信広ハナイノブヒロ

[Journal Article] 【頭頸部悪性腫瘍の疑問に答える】手術手技頸部郭清術の術前プランニングの実際について教えてください2017

[Presentation] 表在リンパ節の超音波診断リンパ節の計測法に関する問題点2017