Mabuchi Yasushi 馬淵泰士

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MABUCHI Yasushi 馬淵泰士

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Researcher Number	80382357
Affiliation (Current)	2025: 和歌山県立医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2017 – 2019: 和歌山県立医科大学, 医学部, 講師 2011 – 2016: 和歌山県立医科大学, 医学部, 助教 2007 – 2009: 和歌山県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator 抗癌剤耐性 / 子宮内膜癌 / インヒビン / アクチビン / 卵巣癌 / アクチビン・インヒビン Except Principal Investigator 腹膜播種 / 免疫寛容 / 腫瘍免疫 / 卵巣癌 … More / 免疫療法 / マウスモデル / 標的治療 / 婦人科腫瘍学 / 腫瘍浸潤リンパ球 / IDO / PD-L1 / ゲノム編集 / マクロファージ / 腫瘍微小環境 / ノックアウトマウス / 血管新生 / ケモカイン / 婦人科腫瘍 / 卵巣がん / 酵素 / death-associated protein kinase / GnRH agonist / アポトーシス / 顆粒膜細胞 / 抗癌剤 / 予防 / CPT-11 / 卵巣機能障害 / 抗がん剤 Less

Novel therapeutic strategy for ovarian cancer targeting immune tolerance-inducing molecules, PD-L1 and IDO, using genome editing technique
- Principal Investigator
  
  INO KAZUHIKO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Wakayama Medical University
Role of chemokine systems and its relation to immunotolerance and angiogenesis in ovarian cancer progression
- Principal Investigator
  
  INO Kazuhiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Wakayama Medical University
Mechanisms of tumor-induced immune tolerance during the process of peritoneal dissemination of ovarian cancer
- Principal Investigator
  
  INO Kazuhiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Wakayama Medical University
Analysis of trmorigenesis and drug-resistance of ovarian/endometrial cancer due to imbalance of activin and inhibin.Principal Investigator
- Principal Investigator
  
  MABUCHI Yasushi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Wakayama Medical University
PREVENTIVE ENDOCRINE THERAPY FOR ANTICANCER DRUG-INDUCED OVARIAN FAILURE
- Principal Investigator
  
  UTSUNOMIYA Tomoko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Wakayama Medical University

All 2018 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Prognostic impact of primary tumor SUV(max) on preoperative (18)F-fluoro-2-deoxy-D-glucose positron emission tomography and computed tomography in endometrial cancer and uterine carcinosarcoma2016
- Author(s)
  Yahata T, Yagi S, Mabuchi Y, Tanizaki Y, Kobayashi A, Yamamoto M, Mizoguchi M,Nanjo S, Shiro M, Ota N, Minami S, Terada M, Ino K
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 5 Pages: 467-474
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462535
[Journal Article] Primary tumor SUV(max) on preoperative FDG-PET/CT is a prognostic indicator in stage IA2-IIB cervical cancer patients treated with radical hysterectomy2016
- Author(s)
  Yagi S, Yahata T, Mabuchi Y, Tanizaki Y, Kobayashi A, Shiro M, Ota N, Minami S, Terada M, Ino
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 5 Pages: 216-222
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462535
[Journal Article] Clinicopathologic Factors of Cervical Adenocarcinoma Stages IB to IIB2015
- Author(s)
  Mabuchi Y, Yahata T, Kobayashi A, Tanizaki Y, Shiro M, Ota N, Yagi S, Minami S, Ino K
- Journal Title
  
  Int J Gynecol Cancer
  
  Volume: 25 Issue: 9 Pages: 1677-1682
- DOI
  10.1097/igc.0000000000000542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462535, KAKENHI-PROJECT-26861338
[Journal Article] Indoleamine 2,3-dioxygenase promotes peritoneal metastasis of ovarian cancer by inducing an immunosuppressive environment.2014
- Author(s)
  Tanizaki Y(1), Kobayashi A, Toujima S, Shiro M, Mizoguchi M, Mabuchi Y, Yagi S, Minami S, Takikawa O, Ino K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 105 Issue: 8 Pages: 966-73
- DOI
  10.1111/cas.12445
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23592347, KAKENHI-PROJECT-23592459, KAKENHI-PROJECT-24590397, KAKENHI-PROJECT-26462535, KAKENHI-PROJECT-26861338
[Journal Article] Diagnostic value of preoperative SUVmax on FDG-PET/CT for the detection of ovarian cancer2014
- Author(s)
  Tanizaki Y, Kobayashi A, Shiro M, Ota N, Takano R, Mabuchi Y, Yagi S, Minami S, Terada M, Ino K
- Journal Title
  
  Int J Gynecol Cancer
  
  Volume: 24(3) Issue: 3 Pages: 454-60
- DOI
  10.1097/igc.0000000000000074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592459, KAKENHI-PROJECT-26861338
[Journal Article] Monoclonality of composite large-cell neuroendocrine carcinoma and invasive intestinal-type mucinous adenocarcinoma of the cervix : a case study2013
- Author(s)
  Yasuoka H, Tsujimoto M, Ueda M, Kodama R, Iwahashi Y, Inagaki M, Mabuchi Y, Ino K, Sanke T, Nakamura Y
- Journal Title
  
  Int J Gynecol Pathol
  
  Volume: 32(4) Issue: 4 Pages: 416-20
- DOI
  10.1097/pgp.0b013e318261c35b
- Data Source
  KAKENHI-PROJECT-23592459
[Journal Article] Role of the immune tolerance-inducing molecule indoleamine 2,3-dioxygenase in gynecologic cancers2012
- Author(s)
  Ino K, Tanizaki Y, Kobayashi A, Toujima S, Mabuchi Y, Minami S
- Journal Title
  
  Journal of Cancer Science ＆ Therapy
  
  Volume: 4(S13) Pages: 1-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592459
[Journal Article] Clinicopathological significance of podocalyxin and phosphorylated ezrin in uterine endometrioid adenocarcinoma2012
- Author(s)
  Yasuoka H, Tsujimoto M, Inagaki M, Kodama R, Tsuji H, Iwahashi Y, Mabuchi Y, Ino K, Sanke T, Nakamura Y
- Journal Title
  
  J Clin Pathol
  
  Volume: 65(5) Issue: 5 Pages: 399-402
- DOI
  10.1136/jclinpath-2011-200359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592459, KAKENHI-PROJECT-24790357
[Journal Article] Role of the renin-angiotensin system in gynecologic cancers2011
- Author(s)
  Ino K, Shibata K, Yamamoto E, Kajiyama H, Nawa A, Mabuchi Y, Yagi S, Minami S, Tanizaki Y, Kobayashi A, Kikkawa F
- Journal Title
  
  Curr Cancer Drug Targets
  
  Volume: 11(4):. Pages: 405-11
- Data Source
  KAKENHI-PROJECT-23592459
[Journal Article] Immunohistochemical localization of inhibin and activin subunits,activin receptors and Smads in ovarian endomtriosis2010
- Author(s)
  Yasushi Mabuchi, Mareo Yamoto, Sawako Minami, Naohiko Umesski
- Journal Title
  
  International Journal of Molecular Medicine 25
  
  Pages: 17-23
- Data Source
  KAKENHI-PROJECT-20791157
[Journal Article] Immunohistochemical localization of inhibin and activin subunits, activin receptors and Smads in ovarian endometriosis2010
- Author(s)
  Yasushi Mabuchi, Mareo Yamoto, Sawako Minami, Naohiko Umesaki
- Journal Title
  
  International Journal of Molecular Medicine 25
  
  Pages: 17-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791157
[Presentation] CRISPR/Cas9-mediated genome editing and efficient PD-L1 disruption on tumor cells promote antitumor immunity and suppress ovarian cancer progression in a mouse model2018
- Author(s)
  Tamaki Yahata, Naoyuki Iwahashi, Mika Mizoguchi, Madoka Yamamoto, Noriyuki, Sasaki, Michihisa Shiro, Yasushi Mabuchi, Shigetaka Yagi, Sawako Minami, Kazuhiko Ino
- Organizer
  第70回日本産科婦人科学会学術講演会（仙台）
- Data Source
  KAKENHI-PROJECT-17K11293
[Presentation] Pivotal roles of CX3CL1-CX3CR1 axis on host cells in ovarian cancer progression2013
- Author(s)
  Yuko Tanizaki, Aya Kobayashi, Saori Toujima, Tamaki Yahata, Madoka Yamamoto, Michihisa Shiro, Nami Ota, Yasushi Mabuchi, Shigetaka Yagi, Sawako Minami, Toshikazu Kondo, Kazuhiko Ino
- Organizer
  The 3rd ASGO / The 55th JSGO
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-23592459
[Presentation] Suppression of STAT1 signal pathways reduces ovarian cancer progression2013
- Author(s)
  Aya Kobayashi, Yuko Tanizaki, Saori Toujima, Tamaki Yahata, Madoka Yamamoto, Michihisa Shiro, Nami Ota, Yasushi Mabuchi, Shigetaka Yagi, Sawako Minami, Toshikazu Kondo, Kazuhiko Ino
- Organizer
  The 3rd ASGO / The 55th JSGO
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-23592459
[Presentation] 免疫寛容を誘導するIndoleamine 2,3-dioxygenaseは卵巣癌腹膜播種を促進し、新規標的治療の候補分子になり得る2012
- Author(s)
  谷﨑優子、小林彩、東嶋左緒里、山本円、馬淵泰士、八木重孝、岩橋正明、南佐和子、井箟一彦
- Organizer
  第11回婦人科がん分子標的研究会
- Place of Presentation
  日光.
- Data Source
  KAKENHI-PROJECT-23592459
[Presentation] 免疫寛容を誘導するIndoleamine 2,3-dioxygenaseは卵巣癌腹膜播種を促進し、新規標的治療の候補分子になり得る2012
- Author(s)
  谷﨑優子、小林彩、東嶋左緒里、山本円、馬淵泰士、八木重孝、岩橋正明、南佐和子、井箟一彦
- Organizer
  第11回婦人科がん分子標的研究会学術集会
- Place of Presentation
  日光
- Data Source
  KAKENHI-PROJECT-23592459
[Presentation] 免疫寛容誘導分子IDOは卵巣癌腹膜播種を促進する2012
- Author(s)
  谷崎優子、小林彩、山本円、馬淵泰士、岩橋正明、南佐和子、井箟一彦
- Organizer
  第64回日本産科婦人科学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23592459
[Presentation] 免疫寛容分子IDOは卵巣癌腹膜播種を促進する2012
- Author(s)
  谷﨑優子、小林彩、山本円、馬淵泰士、岩橋正明、南佐和子、井箟一彦
- Organizer
  第64回日本産科婦人科学会学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23592459
[Presentation] CX3CL1-CX3CR1システムは腫瘍随伴マクロファージの動員を介して卵巣癌腹膜播種を促進する
- Author(s)
  谷﨑優子，小林彩，溝口美佳，城道久，太田菜美，馬淵泰士，八木重孝，南佐和子，井箟一彦
- Organizer
  第67回日本産科婦人科学会
- Place of Presentation
  横浜
- Year and Date
  2015-04-10 – 2015-04-12
- Data Source
  KAKENHI-PROJECT-26462535
[Presentation] 卵巣癌の増殖・進展におけるCCR5の病態生理学的役割についての検討
- Author(s)
  小林彩，谷﨑優子，瀧口義弘，馬淵泰士，八木重孝，南佐和子，井箟一彦
- Organizer
  第56回日本婦人科腫瘍学会
- Place of Presentation
  宇都宮
- Year and Date
  2014-07-17 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-26462535

1. INO Kazuhiko (60303640)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
2. IKEJIMA Miwa (70433349)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 近藤稔和 (70251923)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. UTSUNOMIYA Tomoko (60382355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TANAKA Tetsuji (80275255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YUKAWA Kazunori (20301434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KOKAWA Katsuji (80254548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. BOUSHI Eiji (60433348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. UMESAKI Naohiko (20106339)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. UTSUNOMIYA Hirotoshi (60264876)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. LI Li

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Mabuchi Yasushi 馬淵 泰士

MABUCHI Yasushi 馬淵 泰士

Research Projects

Research Products

Co-Researchers

Novel therapeutic strategy for ovarian cancer targeting immune tolerance-inducing molecules, PD-L1 and IDO, using genome editing technique

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of chemokine systems and its relation to immunotolerance and angiogenesis in ovarian cancer progression

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of tumor-induced immune tolerance during the process of peritoneal dissemination of ovarian cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of trmorigenesis and drug-resistance of ovarian/endometrial cancer due to imbalance of activin and inhibin.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

PREVENTIVE ENDOCRINE THERAPY FOR ANTICANCER DRUG-INDUCED OVARIAN FAILURE

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Prognostic impact of primary tumor SUV(max) on preoperative (18)F-fluoro-2-deoxy-D-glucose positron emission tomography and computed tomography in endometrial cancer and uterine carcinosarcoma2016

Author(s)

Journal Title

Data Source

[Journal Article] Primary tumor SUV(max) on preoperative FDG-PET/CT is a prognostic indicator in stage IA2-IIB cervical cancer patients treated with radical hysterectomy2016

Author(s)

Journal Title

Data Source

[Journal Article] Clinicopathologic Factors of Cervical Adenocarcinoma Stages IB to IIB2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Indoleamine 2,3-dioxygenase promotes peritoneal metastasis of ovarian cancer by inducing an immunosuppressive environment.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diagnostic value of preoperative SUVmax on FDG-PET/CT for the detection of ovarian cancer2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Monoclonality of composite large-cell neuroendocrine carcinoma and invasive intestinal-type mucinous adenocarcinoma of the cervix : a case study2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of the immune tolerance-inducing molecule indoleamine 2,3-dioxygenase in gynecologic cancers2012

Author(s)

Journal Title

Data Source

[Journal Article] Clinicopathological significance of podocalyxin and phosphorylated ezrin in uterine endometrioid adenocarcinoma2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of the renin-angiotensin system in gynecologic cancers2011

Author(s)

Journal Title

Data Source

[Journal Article] Immunohistochemical localization of inhibin and activin subunits,activin receptors and Smads in ovarian endomtriosis2010

Author(s)

Journal Title

Data Source

Mabuchi Yasushi 馬淵泰士

MABUCHI Yasushi 馬淵泰士