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Kasashima Katsumi  笠嶋 克巳

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… Alternative Names

KASASHIMA Katsumi  笠嶋 克巳

笠島 克己  カサシマ カツミ

笠島 昌宏  カサジマ カツミ

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Researcher Number 80382844
Other IDs
Affiliation (Current) 2025: 自治医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2012 – 2017: 自治医科大学, 医学部, 講師
2007: 自治医科大学, 医学部, 助教
2006: 自治医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Pathological medical chemistry
Except Principal Investigator
Anesthesiology/Resuscitation studies
Keywords
Principal Investigator
TFAM / ミトコンドリアDNA / 欠失型mtDNA蓄積 / ミトコンドリアDNA (mtDNA) / mtDNA分配 / 欠失型ミトコンドリアDNA / 線虫 / 欠失型mtDNAの蓄積 / ヌクレオイド / ミトコンドリア / 分配 … More
Except Principal Investigator
… More PONV / RNA結合タンパク質 / RNA / ラット / マウス / セボフルラン / 中枢性麻酔作用 / 吸入麻酔薬 / 神経性RNA結合タンパク質 Less
  • Research Projects

    (3 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (5 People)
  •  Accumulation mechanism of mutant mitochondrial DNA in C. elegansPrincipal Investigator

    • Principal Investigator
      Kasashima Katsumi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Jichi Medical University
  •  Segregation mechanism of human mitochondrial genome through TFAMPrincipal Investigator

    • Principal Investigator
      KASASHIMA Katsumi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Jichi Medical University
  •  神経性RNA結合タンパク質に着目した吸入麻酔薬の中枢性麻酔薬作用の解析

    • Principal Investigator
      佐藤 正章
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Jichi Medical University

All 2017 2016 2015 2014 2013 2012

All Journal Article Presentation

  • [Journal Article] Characterization of Bombyx mori mitochondrial transcription factor A, a conserved regulator of mitochondrial DNA2017

    • Author(s)
      Sumitani Megumi、Kondo Mari、Kasashima Katsumi、Endo Hitoshi、Nakamura Kaoru、Misawa Toshihiko、Tanaka Hiromitsu、Sezutsu Hideki
    • Journal Title

      Gene

      Volume: 608 Pages: 103-113

    • DOI

      10.1016/j.gene.2016.12.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11248, KAKENHI-PROJECT-15K19029
  • [Journal Article] Inhibition of Malaria Infection in Transgenic Anopheline Mosquitoes Lacking Salivary Gland Cells.2016

    • Author(s)
      Yamamoto DS, Sumitani M, Kasashima K, Sezutsu H, Matsuoka H.
    • Journal Title

      PLoS Pathog.

      Volume: 12 Issue: 9 Pages: e1005872-e1005872

    • DOI

      10.1371/journal.ppat.1005872

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460181, KAKENHI-PROJECT-15K19029, KAKENHI-PROJECT-16K18824
  • [Journal Article] Developmentally-regulated RNA-binding Protein 1 (Drb1)/RNA-binding Motif Protein 45 (RBM45), a Nuclear-cytoplasmic Trafficking Protein, Forms TAR DNA-binding Protein 43 (TDP-43)-mediated Cytoplasmic Aggregates2016

    • Author(s)
      5.Mashiko T, Sakashita E, Kasashima K, Tominaga K, Kuroiwa K, NozakiY, Matsuura T, Hamamoto T, Endo H
    • Journal Title

      J Biol Chem

      Volume: 291 Issue: 29 Pages: 14996-15007

    • DOI

      10.1074/jbc.m115.712232

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670170, KAKENHI-PROJECT-15K19029
  • [Journal Article] Establishment of a specific cell death induction system in Bombyx mori by a transgene with the conserved apoptotic regulator, mouse Bcl-2-associated X protein (mouse Bax).2015

    • Author(s)
      M. Sumitani, T. Sakurai, Katsumi Kasashima, S. Kobayashi, K. Uchino, R. Kanzaki, T. Tamura, and H. Sezutsu
    • Journal Title

      Insect Molecular Biology

      Volume: 24 Issue: 6 Pages: 671-680

    • DOI

      10.1111/imb.12192

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19029, KAKENHI-PROJECT-26712027
  • [Journal Article] Interaction of human mitochondrial transcription factor A in mitochondria: its involvement in the dynamics of mitochondrial DNA nucleoids.2015

    • Author(s)
      Katsumi Kasashima and Hitoshi Endo
    • Journal Title

      Genes to Cells

      Volume: 20 Issue: 12 Pages: 1017-1027

    • DOI

      10.1111/gtc.12306

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K19029
  • [Journal Article] Dynamic regulation of mitochondrial genome maintenance in germ cells2014

    • Author(s)
      Kasashima K., et al.
    • Journal Title

      Reproductive Medicine and Biology

      Volume: 13 Issue: 1 Pages: 11-20

    • DOI

      10.1007/s12522-013-0162-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790324
  • [Journal Article] Translational repression of the McKusick-Kaufman syndrome transcript by unique upstream open reading frames encoding mitochondrial proteins with alternative polyadenylation sites2013

    • Author(s)
      Akimoto, C. Sakashita, E., Kasashima, K., Kuroiwa, K., Tominaga, K., Hamamoto, T., and Endo, H.
    • Journal Title

      Biochem Biophys Acta

      Volume: 1830 Issue: 3 Pages: 2728-2738

    • DOI

      10.1016/j.bbagen.2012.12.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590290, KAKENHI-PROJECT-24613006, KAKENHI-PROJECT-24790324
  • [Journal Article] Maintenance of mitochondrial genome distribution by mitochondrial AAA+ protein.ClpX. Exp2012

    • Author(s)
      Kasashima, K., Sumitani, M., and Endo, H
    • Journal Title

      Cell Res

      Volume: 318 Issue: 18 Pages: 2335-2343

    • DOI

      10.1016/j.yexcr.2012.07.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590290, KAKENHI-PROJECT-24790324
  • [Journal Article] ミトコンドリア膜の機能的新タンパク質類ープロヒビチン2012

    • Author(s)
      遠藤仁司、笠嶋克巳
    • Journal Title

      生体の科学

      Volume: 63 Pages: 432-433

    • Data Source
      KAKENHI-PROJECT-24790324
  • [Presentation] 保存されたTFAMのdimer化とその様式および細胞内の役割について2017

    • Author(s)
      笠嶋克巳、炭谷めぐみ、遠藤仁司
    • Organizer
      第40回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-15K19029
  • [Presentation] Property of C. elegans HMG-5, a homologue of TFAM, and its implication into mtDNA maintenance.2016

    • Author(s)
      Katsumi Kasashima, Megumi Sumitani, Hitoshi Endo
    • Organizer
      The 13th Conference of Asian Society for Mitochondrial Research and Medicine
    • Place of Presentation
      TKP Garden City Shinagawa (Tokyo, Shinagawa)
    • Year and Date
      2016-10-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19029
  • [Presentation] TFAMによるミトコンドリアDNA動態調節機構の解析2015

    • Author(s)
      笠嶋克巳、遠藤仁司
    • Organizer
      第38回日本分子生物学会年会(第88回日本生化学会大会との合同大会)
    • Place of Presentation
      神戸国際展示場(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K19029
  • [Presentation] ミトコンドリア内におけるTFAM間相互作用に必要なドメインの同定2014

    • Author(s)
      笠嶋克巳、遠藤仁司
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都国際会館
    • Year and Date
      2014-10-17
    • Data Source
      KAKENHI-PROJECT-24790324
  • [Presentation] TFAMによるミトコンドリアゲノム分配機構の解析2013

    • Author(s)
      笠嶋克巳
    • Organizer
      日本生化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24790324
  • [Presentation] Molecular mechanism of TFAM-regulated mitochondrial DNA/Nucleoid distribution2013

    • Author(s)
      Katsumi Kasashima
    • Organizer
      The 4th International Symposium on Dynamics of Mitochondria
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-24790324
  • [Presentation] ミトコンドリアシャペロンClpXによるTFAM調節機構の解析2012

    • Author(s)
      笠嶋克巳
    • Organizer
      日本ミトコンドリア学会
    • Place of Presentation
      筑波大学
    • Data Source
      KAKENHI-PROJECT-24790324
  • [Presentation] ヒトClpXはTFAMを介してミトコンドリアゲノムの分布を調節する2012

    • Author(s)
      笠嶋克巳
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24790324
  • 1.  佐藤 正章 (70382918)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  遠藤 仁司 (50221817)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 3.  蛭田 昌宏 (90337337)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  MATSUOKA Hiroyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  松浦 徹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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