Hirono Haruka 廣野玄

… Alternative Names

HIRONO Haruka 廣野玄

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Researcher Number	80386268
Other IDs
Affiliation (Current)	2025: 日本歯科大学, 新潟生命歯学部, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 日本歯科大学, 新潟生命歯学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 52010:General internal medicine-related / Respiratory organ internal medicine Except Principal Investigator Basic Section 52010:General internal medicine-related / Applied pharmacology
Keywords	Principal Investigator 持続陽圧呼吸療法 / 非アルコール性脂肪性肝疾患 / 慢性間欠的低酸素 / 閉塞性睡眠時無呼吸症 / 脂肪肝 / 肝線維化 / NASH / 低酸素血症 / 非アルコール性脂肪肝炎 / 睡眠時無呼吸症候群 … More / 動脈硬化 / 間欠的低酸素血症 / 睡眠時無呼吸 / RANTES / 非アルコール性脂肪肝疾患 / 持続陽圧呼吸 / M2BPGi / フィブロスキャン / 肝障害 / NAFLD / 持続的陽圧呼吸療法 / CPAP / 夜間低酸素血症 … More Except Principal Investigator 睡眠時無呼吸症候群 / 炎症 / SAS / 無呼吸指数 / 吹田スコア / ＳＡＳ / 血小板マイクロパーティクル / IL-18 / 血小板活性化 / マクロファージ / 動脈硬化リスク / トランスレーショナル研究 / 活性血小板 / 動脈硬化 / 睡眠時無呼吸症 / 脂肪肝 / CCL5 / 食道pH/インピーダンス検査 / 胃食道逆流症 / 人工バイオ肝臓 / 脱落歯 / 薬剤スクリーニング / 動物モデル / 重症肝障害 / 歯髄バンク / テーラーメード医療 / 薬剤毒性スクリーニング / 歯髄幹細胞 / ヒトDNA特異的PCR / 劇症肝炎 / テーラーメイド医療 / ヒト細胞特異的PCR / 再生医療 / 歯の細胞バンク / 肝細胞 / 間葉系幹細胞 / 歯髄細胞 Less

睡眠時無呼吸症に着目した、脂肪肝と動脈硬化ネットワークの解明とその改善法の提案Principal Investigator
- Principal Investigator
  
  廣野玄
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The Nippon Dental University
消化管逆流の視点から考える、誤嚥性肺炎に対する新しい予防戦略の確立
- Principal Investigator
  
  渡邉和彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The Nippon Dental University
Exploration of new clinical markers for arteriosclerosis that contribute the inhibition of vascular events induced by obstructive sleep apnea
- Principal Investigator
  
  Hasegawa Katsuhiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The Nippon Dental University
Identification of NASH patients who obtain therapeutic benefit from the improvement of nocturnal intermittent hypoxia and its application for clinical practice.Principal Investigator
- Principal Investigator
  
  Hirono Haruka
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The Nippon Dental University
Establishment of new treatment strategy for sleep apnea syndrome with less burden on patients
- Principal Investigator
  
  Watanabe Kazuhiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The Nippon Dental University
Regenetative medicine using decidouous teeth preparing for future diseases
- Principal Investigator
  
  Shogo Ohkoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  The Nippon Dental University
Establishment of new treatment strategy for NASH by elucidating the mechanisms of fibrosis progression due to nocturnal intermittent hypoxia.Principal Investigator
- Principal Investigator
  
  HIRONO Haruka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The Nippon Dental University

All 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Impact of continuous positive airway pressure therapy for nonalcoholic fatty liver disease in patients with obstructive sleep apnea2021
- Author(s)
  Hirono H、Watanabe K、Hasegawa K、Kohno M、Terai S、Ohkoshi　S
- Journal Title
  
  World J Clinical Cases
  
  Volume: 9 Pages: 5112-5125
- Open Access
- Data Source
  KAKENHI-PROJECT-21K07329
[Journal Article] Anti-Dementia Drugs and Hepatotoxicity Report of Two Cases2018
- Author(s)
  Hirono Haruka、Watanabe Kazuhiko、Hasegawa Katsuhiko、Hiroyasu Kazuhiko、Shibasaki Koichi、Ohkoshi Shogo
- Journal Title
  
  International Journal of Gerontology
  
  Volume: 1 Issue: 3 Pages: 1-3
- DOI
  10.1016/j.ijge.2018.02.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08966
[Journal Article] Dental pulp cell bank as a possible future source of individual hepatocytes2018
- Author(s)
  Ohkoshi S, Hirono H, Nakahara T, Ishikawa H.
- Journal Title
  
  World J Hepatol.
  
  Volume: 10 Issue: 10 Pages: 702-707
- DOI
  10.4254/wjh.v10.i10.702
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08966, KAKENHI-PROJECT-18K09733, KAKENHI-PROJECT-16K09564
[Journal Article] 閉塞性睡眠時無呼吸症候群と脂肪肝　－肝フィブロスキャン検査を用いたアプローチー2017
- Author(s)
  大越章吾、廣野玄、渡邉和彦、長谷川勝彦、斎藤満美子、安井浩美
- Journal Title
  
  歯学
  
  Volume: 105 Pages: 21-25
- Data Source
  KAKENHI-PROJECT-16K09564
[Journal Article] Evaluation of Hepatic Steatosis with Controlled Attenuation Parameter (CAP) Technology2017
- Author(s)
  Ohkoshi S, Hirono H, Watanabe K and Hasegawa K
- Journal Title
  
  Journal of Gastroenterology, Hepatology and Endoscopy
  
  Volume: 2 Pages: 1-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09564
[Journal Article] 睡眠時無呼吸症候群における夜間間欠的低酸素血症の改善が肝線維化・脂肪化に及ぼす影響の解析2017
- Author(s)
  廣野玄、渡邉和彦、長谷川勝彦、河野正己、大越章吾
- Journal Title
  
  新潟県医師会報
  
  Volume: 802 Pages: 7-8
- Data Source
  KAKENHI-PROJECT-16K09564
[Presentation] 閉塞性睡眠時無呼吸症候群における夜間の一過性下部食道括約筋弛緩(TLESR)の発生には、わずかな嚥下反応が関与する可能性がある-PSG・食道pH/インピーダンス同時測定からの考察-2021
- Author(s)
  渡辺和彦、廣野玄、長谷川勝彦、大越章吾
- Organizer
  第63回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-18K07429
[Presentation] 夜間睡眠ポリグラフと食道pH/インピーダンス同時測定から検討した、閉塞性睡眠時無呼吸症候群と胃食道逆流症の関連性2021
- Author(s)
  渡辺和彦、廣野玄、長谷川勝彦、大越章吾、河野茜、猪子芳美、河野正己
- Organizer
  日本睡眠学会第46回定期学術集会
- Data Source
  KAKENHI-PROJECT-18K07429
[Presentation] 改訂Fスケール問診を用いた、閉塞性睡眠時無呼吸症候群と胃食道逆流症の関連性及び治療効果の検討2020
- Author(s)
  渡辺和彦、廣野玄、長谷川勝彦、大越章吾
- Organizer
  第62回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-18K07429
[Presentation] 夜間低酸素血症の影響を考慮にいれたNAFLDの治療指針の提案2019
- Author(s)
  廣野　玄
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16K09564
[Presentation] いびき症に潜む動脈硬化危険因子　～睡眠から発する検診メッセージ～　（肝フィブロスキャン検査を用いたアプローチ）2018
- Author(s)
  廣野玄、渡邉和彦、長谷川勝彦、大越章吾、河野正己
- Organizer
  2017年度　新潟市医師会地域医療研究助成発表会
- Data Source
  KAKENHI-PROJECT-16K09564
[Presentation] 夜間低酸素血症がNAFLDに及ぼすインパクト2018
- Author(s)
  廣野　玄
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16K09564
[Presentation] 睡眠時無呼吸症候群（SAS）と脂肪肝の関係　～フィブロスキャンを用いて～2017
- Author(s)
  廣野玄、渡邉和彦、長谷川勝彦、大越章吾、猪子芳美、河野正己
- Organizer
  第14回　新潟睡眠呼吸障害研究会
- Data Source
  KAKENHI-PROJECT-16K09564

1. Shogo Ohkoshi (70231199)

# of Collaborated Projects: 7 results

# of Collaborated Products: 11 results
2. Hasegawa Katsuhiko (60328870)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
3. Watanabe Kazuhiko (70742758)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
4. 河野正己 (20170201)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
5. 松田康伸 (40334669)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 石川博 (30089784)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 猪子芳美 (50386265)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 白野美和 (60318558)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 道川誠 (40270912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hirono Haruka 廣野 玄

HIRONO Haruka 廣野 玄

Research Projects

Research Products

Co-Researchers

睡眠時無呼吸症に着目した、脂肪肝と動脈硬化ネットワークの解明とその改善法の提案Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

消化管逆流の視点から考える、誤嚥性肺炎に対する新しい予防戦略の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploration of new clinical markers for arteriosclerosis that contribute the inhibition of vascular events induced by obstructive sleep apnea

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of NASH patients who obtain therapeutic benefit from the improvement of nocturnal intermittent hypoxia and its application for clinical practice.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of new treatment strategy for sleep apnea syndrome with less burden on patients

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regenetative medicine using decidouous teeth preparing for future diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of new treatment strategy for NASH by elucidating the mechanisms of fibrosis progression due to nocturnal intermittent hypoxia.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Impact of continuous positive airway pressure therapy for nonalcoholic fatty liver disease in patients with obstructive sleep apnea2021

Author(s)

Journal Title

Data Source

[Journal Article] Anti-Dementia Drugs and Hepatotoxicity Report of Two Cases2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dental pulp cell bank as a possible future source of individual hepatocytes2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 閉塞性睡眠時無呼吸症候群と脂肪肝 －肝フィブロスキャン検査を用いたアプローチー2017

Author(s)

Journal Title

Data Source

[Journal Article] Evaluation of Hepatic Steatosis with Controlled Attenuation Parameter (CAP) Technology2017

Author(s)

Journal Title

Data Source

[Journal Article] 睡眠時無呼吸症候群における夜間間欠的低酸素血症の改善が肝線維化・脂肪化に及ぼす影響の解析2017

Author(s)

Journal Title

Data Source

[Presentation] 閉塞性睡眠時無呼吸症候群における夜間の一過性下部食道括約筋弛緩(TLESR)の発生には、わずかな嚥下反応が関与する可能性がある-PSG・食道pH/インピーダンス同時測定からの考察-2021

Author(s)

Organizer

Data Source

[Presentation] 夜間睡眠ポリグラフと食道pH/インピーダンス同時測定から検討した、閉塞性睡眠時無呼吸症候群と胃食道逆流症の関連性2021

Author(s)

Organizer

Hirono Haruka 廣野玄

HIRONO Haruka 廣野玄

[Journal Article] 閉塞性睡眠時無呼吸症候群と脂肪肝　－肝フィブロスキャン検査を用いたアプローチー2017

[Presentation] いびき症に潜む動脈硬化危険因子　～睡眠から発する検診メッセージ～　（肝フィブロスキャン検査を用いたアプローチ）2018

[Presentation] 睡眠時無呼吸症候群（SAS）と脂肪肝の関係　～フィブロスキャンを用いて～2017