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Sasai Noriaki  笹井 紀明

… Alternative Names

SASAI Noriaki  笹井 紀明

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Researcher Number 80391960
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-0360-1138
Affiliation (Current) 2025: 奈良先端科学技術大学院大学, 先端科学技術研究科, 准教授
Affiliation (based on the past Project Information) *help 2018 – 2025: 奈良先端科学技術大学院大学, 先端科学技術研究科, 准教授
2015 – 2017: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 准教授
2005 – 2007: 独立行政法人理化学研究所, 細胞分化・器官発生研究グループ, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 44020:Developmental biology-related / Developmental biology / Cell biology / Complex systems / Biological Sciences / Biology of Cells to Organisms, and related fields
Except Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 48040:Medical biochemistry-related / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 44020:Developmental biology-related
Keywords
Principal Investigator
ニワトリ胚 / 神経管 / 中枢神経系 / ソニック・ヘッジホッグ / パターン形成 / Prominin-1 / オルガノイド / エピゲノム / 細胞増殖 / 胚性幹細胞 … More / 前駆細胞 / 増殖と分化 / ウズラ胚 / コンピテンス / 初期胚 / アフリカツメガエル / マウス胚 / ゲノム編集 / 細胞分化 / 神経分化 / 幹細胞 / モルフォゲン / 神経損傷 / マウス / BMPシグナル / 大脳腹側部 / ES細胞 / Phc1 / マウス幹細胞 / 光受容細胞 / 網膜 / 網羅的発現解析 / 網膜色素変性症 / CRISPR/Cas9 / 網膜オルガノイド / 種特異的な発生時計 / サイズ制御 / 器官サイズ / キメラ胚 / 発生時間 / フィードバック効果 / 量的比率 / 神経発生 / 中枢神経 / シグナル活性 / シグナルの経時的変化 / シグナル因子 / 神経発生学 / サイズ決定 / mRNAシーケンス法 / 介在神経 / 底板細胞 / 転写因子 / 細胞外シグナル因子 / signal transduction / Xenopus laevis / small GTPase / neurotrophin receptor / morphogenetic movements / 細胞運動 / ニワトリ / シグナル伝達 / 低分子GTPアーゼ / ニューロトロフィン受容体 / 形態形成運動 / Wnt / 細胞外マトリックス / BMP … More
Except Principal Investigator
遺伝子発現 / エピジェネティック因子 / 心臓前駆細胞 / 転写調節因子 / 発生 / 体節 / 先天性心疾患 / 胚発生 / ノックアウトマウス / ES細胞 / 神経分化 / 神経細胞 / 神経幹細胞 / 細胞増殖 / アポトーシス / 中枢神経系の発生 / コンディショナル欠損(cKO)マウス / メチル化DNA結合タンパク質 / 胚盤胞補完法 / 異種間キメラ / 臓器移植 / 脱細胞 / 再生医療 / 奇形 / 体軸骨格 / Cell-cell communication / 神経 / 細胞の社会性 / 細胞の集団行動 / 有毛細胞 / マウス / ゼブラフィッシュ / クッペル胞 / 側線器官 / 器官サイズ Less
  • Research Projects

    (16 results)
  • Research Products

    (83 results)
  • Co-Researchers

    (20 People)
  •  クロマチン制御因子がもたらす脳サイズ調節遺伝子ネットワークの解明Principal Investigator

    • Principal Investigator
      笹井 紀明
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 44020:Developmental biology-related
    • Research Institution
      Nara Institute of Science and Technology
  •  Cell-cell communicationから紐解く、心臓前駆細胞を取り巻く細胞社会の解明

    • Principal Investigator
      白井 学
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  The site of action of intra- and extra-embryonic fluctuations that cause malformation and mechanisms of robustness that prevent them

    • Principal Investigator
      別所 康全
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Nara Institute of Science and Technology
  •  胎児の臓器を立体構造を保持したまま成体内で育てる研究

    • Principal Investigator
      磯谷 綾子
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Nara Institute of Science and Technology
  •  The role of methylated DNA-binding proteins in embryonic central nervous system development

    • Principal Investigator
      松田 永照
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Nara Institute of Science and Technology
  •  Crosstalk between transcriptional factors and epigenetic factors in cardiac progenitor cell development.

    • Principal Investigator
      Shirai Manabu
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  The Regulatory mechanisms leading Cellular Photosensitivity and Organ Robustness by Retinal OrganoidsPrincipal Investigator

    • Principal Investigator
      笹井 紀明
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Nara Institute of Science and Technology
  •  Positional and quantitative regulation of the central nervous cells by interaction of pattern formation, proliferation and differentiation timingPrincipal Investigator

    • Principal Investigator
      Sasai Noriaki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 44020:Developmental biology-related
    • Research Institution
      Nara Institute of Science and Technology
  •  Regulation of the organ size and conservation of pattern formation by controlled by species-specific developmental clocksPrincipal Investigator

    • Principal Investigator
      笹井 紀明
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Nara Institute of Science and Technology
  •  Epigenetic regulation of cardiac progenitor cells development in lateral plate mesoderm/pharyngeal region.

    • Principal Investigator
      Shirai Manabu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  The mechanism of organ-size determination via social behavior of their progenitor cells in animal development

    • Principal Investigator
      Bessho Yasumasa
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 44020:Developmental biology-related
    • Research Institution
      Nara Institute of Science and Technology
  •  Elucidation of the mechanism for the determination of the size of the central nervous system by developing a new screening methodPrincipal Investigator

    • Principal Investigator
      SASAI NORIAKI
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Biology of Cells to Organisms, and related fields
    • Research Institution
      Nara Institute of Science and Technology
  •  Molecular mechanisms leading to the balance between qualitative and quantitative changes of the neural progenitor cellsPrincipal Investigator

    • Principal Investigator
      Sasai Noriaki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Developmental biology
    • Research Institution
      Nara Institute of Science and Technology
  •  Dynamic regulation of the genes involved in the neural tube pattern formationPrincipal Investigator

    • Principal Investigator
      Sasai Noriaki
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Developmental biology
    • Research Institution
      Nara Institute of Science and Technology
  •  Anterior neural development requires the matrix protein Del1, which attenuates intracellular Wnt signalingPrincipal Investigator

    • Principal Investigator
      INOMATA Hidehiko, 笹井 紀明
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Regulation of Morphogenetic movements by the neurotrophin-related transmembrane protein NRHPrincipal Investigator

    • Principal Investigator
      SASAI Noriaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      RIKEN

All 2024 2023 2022 2021 2020 2019 2018 2017 2015 2008 2007

All Journal Article Presentation

  • [Journal Article] Regulation of progenitor cell survival by a novel chromatin remodelling factor during neural tube development2024

    • Author(s)
      Noriaki Sasai, Shogo Tada, Jumi Ohshiro, Chikara Kogiso, Takuma Shinozuka
    • Journal Title

      Development Growth and Differentiation

      Volume: 66 Issue: 1 Pages: 89-100

    • DOI

      10.1111/dgd.12905

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Journal Article] Combination of blockade of endothelin signalling and compensation of IGF1 expression protects the retina from degeneration2024

    • Author(s)
      Shigesada Naoya、Shikada Naoya、Shirai Manabu、Toriyama Michinori、Higashijima Fumiaki、Kimura Kazuhiro、Kondo Toru、Bessho Yasumasa、Shinozuka Takuma、Sasai Noriaki
    • Journal Title

      Cellular and Molecular Life Sciences

      Volume: 81 Issue: 1 Pages: 1-18

    • DOI

      10.1007/s00018-023-05087-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06382, KAKENHI-PROJECT-20H03263
  • [Journal Article] Acquisition of neural fate by combination of BMP blockade and chromatin modification2023

    • Author(s)
      Ong Agnes Lee Chen、Kokaji Toshiya、Kishi Arisa、Takihara Yoshihiro、Shinozuka Takuma、Shimamoto Ren、Isotani Ayako、Shirai Manabu、Sasai Noriaki
    • Journal Title

      iScience

      Volume: 26 Issue: 11 Pages: 108257-108257

    • DOI

      10.1016/j.isci.2023.108257

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02889
  • [Journal Article] Manipulation of signal gradient and transcription factors recapitulates multiple hypothalamic identities2023

    • Author(s)
      Maho Yamamoto, Agnes Ong Lee Chen, Takuma Shinozuka, Manabu Shirai, Noriaki Sasai.
    • Journal Title

      Stem Cells

      Volume: N/A Issue: 5 Pages: 453-467

    • DOI

      10.1093/stmcls/sxad018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Journal Article] Acquisition of neural fate by combination of BMP blockade and chromatin modification2023

    • Author(s)
      Ong Agnes Lee Chen、Kokaji Toshiya、Kishi Arisa、Takihara Yoshihiro、Shinozuka Takuma、Shimamoto Ren、Isotani Ayako、Shirai Manabu、Sasai Noriaki
    • Journal Title

      iScience

      Volume: 26 Issue: 10 Pages: 107887-107887

    • DOI

      10.1016/j.isci.2023.107887

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K16349, KAKENHI-PROJECT-20H03263
  • [Journal Article] The Rx transcription factor is required for determination of the retinal lineage and regulates the timing of neuronal differentiation2022

    • Author(s)
      Maho Yamamoto, Agnes Ong Lee Chen, Takuma Shinozuka, Noriaki Sasai
    • Journal Title

      Development Growth and Differentiation

      Volume: 64 Issue: 6 Pages: 318-324

    • DOI

      10.1111/dgd.12796

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03263, KAKENHI-PUBLICLY-20H05036
  • [Journal Article] Heterozygous loss of Zbtb38 leads to early embryonic lethality via the suppression of Nanog and Sox2 expression2022

    • Author(s)
      Nishio Miki、Matsuura Takuya、Hibi Shunya、Ohta Shiomi、Oka Chio、Sasai Noriaki、Ishida Yasumasa、Matsuda Eishou
    • Journal Title

      Cell Proliferation

      Volume: 55 Issue: 4 Pages: 1-14

    • DOI

      10.1111/cpr.13215

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06883
  • [Journal Article] Sox14 is essential for initiation of interneuron differentiation in the chick spinal cord2021

    • Author(s)
      Taiki Katsuyama, Minori Kadoya, Manabu Shirai, Noriaki Sasai
    • Journal Title

      Research Square

      Volume: -

    • DOI

      10.21203/rs.3.rs-243180/v1

    • Open Access
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Journal Article] Early manifestations and differential gene expression associated with photoreceptor degeneration in Prom1-deficient retina2021

    • Author(s)
      Kobayashi Y,Watanabe S,Ong ALC,Shirai M,Yamashiro C,Ogata T,Higashijima F,Yoshimoto T,Hayano T,Asai Y,Sasai N,Kimura K
    • Journal Title

      Dis Model Mech

      Volume: 14 Issue: 11

    • DOI

      10.1242/dmm.048962

    • NAID

      120007185295

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09805, KAKENHI-PUBLICLY-20H05036
  • [Journal Article] Sox14 is essential for initiation of neuronal differentiation in the chick spinal cord2021

    • Author(s)
      Katsuyama Taiki、Kadoya Minori、Shirai Manabu、Sasai Noriaki
    • Journal Title

      Developmental Dynamics

      Volume: 251 Issue: 2 Pages: 350-361

    • DOI

      10.1002/dvdy.392

    • NAID

      120007165093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02889, KAKENHI-PROJECT-21K15105
  • [Journal Article] Neural induction: Historical views and application to pluripotent stem cells2021

    • Author(s)
      Sasai, N. Kadoya, M. Ong Lee Chen, A.
    • Journal Title

      Dev Growth Differ

      Volume: 63 Issue: 1 Pages: 26-37

    • DOI

      10.1111/dgd.12703

    • NAID

      120006949518

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Journal Article] 脳の領域化2020

    • Author(s)
      笹井 紀明
    • Journal Title

      脳科学辞典

      Volume: -

    • DOI

      10.14931/bsd.9270

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-19H04781, KAKENHI-PROJECT-20H03263
  • [Journal Article] コーディン2020

    • Author(s)
      笹井 紀明
    • Journal Title

      脳科学辞典

      Volume: -

    • DOI

      10.14931/bsd.9269

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-19H04781, KAKENHI-PROJECT-20H03263
  • [Journal Article] Prominin-1 Modulates Rho/ROCK-Mediated Membrane Morphology and Calcium-Dependent Intracellular Chloride Flux.2019

    • Author(s)
      Hori A, Nishide K, Yasukuni Y, Haga K, Kakuta W, Ishikawa Y, Hayes MJ, Ohnuma SI, Kiyonari H, Kimura K, Kondo T, Sasai N.
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 15911-15911

    • DOI

      10.1038/s41598-019-52040-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-19H04781, KAKENHI-PROJECT-17H03684, KAKENHI-PROJECT-17K11451
  • [Journal Article] Hedgehog Signal and Genetic Disorders.2019

    • Author(s)
      Sasai N, Toriyama M, Kondo T.
    • Journal Title

      Frontiers in Genetics

      Volume: 10 Pages: 1103-1103

    • DOI

      10.3389/fgene.2019.01103

    • NAID

      120006772118

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-19H04781, KAKENHI-PROJECT-17H03684, KAKENHI-PROJECT-17K19399, KAKENHI-PROJECT-17H05003
  • [Journal Article] GPR17 is an essential regulator for the temporal adaptation of sonic hedgehog signalling in neural tube development.2019

    • Author(s)
      Yatsuzuka A, Hori A, Kadoya M, Matsuo-Takasaki M, Kondo T, Sasai N.
    • Journal Title

      Development

      Volume: 146

    • DOI

      10.1242/dev.176784

    • NAID

      120006718070

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-19H04781, KAKENHI-PROJECT-17H03684
  • [Journal Article] Negative Regulation of mTOR Signaling Restricts Cell Proliferation in the Floor Plate.2019

    • Author(s)
      Kadoya M, Sasai N.
    • Journal Title

      Frontiers in Neuroscience

      Volume: 13 Pages: 1022-1022

    • DOI

      10.3389/fnins.2019.01022

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-19H04781, KAKENHI-PROJECT-17H03684, KAKENHI-PROJECT-17K19399
  • [Journal Article] GPR17 is an essential component of the negative feedback Loop of the Sonic Hedgehog signalling pathway in neural tube development2018

    • Author(s)
      Atsuki Yatsuzuka, Akiko Hori, Minori Kadoya, Mami Matsuo-Takasaki, Toru Kondo, Noriaki Sasai
    • Journal Title

      BioRxiv

      Volume: -

    • Open Access
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Journal Article] 神経誘導2017

    • Author(s)
      笹井紀明
    • Journal Title

      脳科学辞典

      Volume: -

    • DOI

      10.14931/bsd.2114

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19399, KAKENHI-PROJECT-17H03684
  • [Journal Article] ソニック・ヘッジホッグ2017

    • Author(s)
      笹井紀明
    • Journal Title

      脳科学辞典

      Volume: -

    • DOI

      10.14931/bsd.7348

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19399, KAKENHI-PROJECT-17H03684
  • [Journal Article] Robust Stability of the Embryonic Dorsal Axial Pattern Requires ONT1, a Secreted Scaffold for Chordin Degradation2008

    • Author(s)
      Inomata, H., Haraguchi, T. and Sasai, Y
    • Journal Title

      Cell 134

      Pages: 854-865

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570192
  • [Journal Article] Ectodermal Factor Restricts Mesoderm Differentiation by Inhibiting p532008

    • Author(s)
      Noriaki Sasai
    • Journal Title

      Cell 133

      Pages: 878-890

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570192
  • [Journal Article] Ectodermal Factor Restricts Mesoderm Differentiation by Inhibiting p532008

    • Author(s)
      Sasai, N., Yakura, R,, Kamiya, D., Nakazawa, Y. and Sasai, Y
    • Journal Title

      Cell 133

      Pages: 878-890

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570192
  • [Journal Article] XTsh3 is an essential enhancing factor of canonical Wnt signaling in Xenopus axial determination2007

    • Author(s)
      Onai, T., Matsuo-Takasaki, M., Inomata, H., Aramaki, T., Matsumura, M., Yakura, R., Sasai, N., and Sasai, Y
    • Journal Title

      EMBO J 26

      Pages: 2350-2360

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570192
  • [Journal Article] The secreted EGF-Discoidin factor xDel1 is essential for dorsal development of the Xenopus embryo2007

    • Author(s)
      Arakawa, A., Matsuo-Takasaki, M., Takai, A., Inomata, H., Matsumura, M., Ikeya, M., Takahashi, K., Miyachi, Y., Sasai, N. and Sasai,Y
    • Journal Title

      Developmental Biology 306

      Pages: 160-169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570192
  • [Presentation] BMPシグナルの抑制とクロマチン修飾の協働による神経分化制御2023

    • Author(s)
      Agnes Lee Chen Ong、小鍛冶俊也、篠塚琢磨、白井学、笹井紀明
    • Organizer
      第46回 日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-21H02889
  • [Presentation] ES細胞からのオリゴデンドロサイトと神経堤細胞への分化とSox10の機能解析2023

    • Author(s)
      肥塚梨菜篠塚琢磨笹井紀明
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] 脊髄損傷に応答したShhシグナルの活性化2023

    • Author(s)
      篠塚琢磨笹井紀明
    • Organizer
      日本動物学会 第94回大会
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] Acquisition of Neural Fate by Combination of BMP Blockade and Chromatin Modification2023

    • Author(s)
      Noriaki Sasai Toshiya Kokaji Takuma ShinozukaManabu Shirai Agnes Ong Lee Chen
    • Organizer
      第46回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] 神経幹細胞の分化多様性の解析2023

    • Author(s)
      岸亜吏紗篠塚琢磨笹井紀明
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] アデノ随伴ウイルスベクターの効率的な作成方法と、網膜への導入の検討2023

    • Author(s)
      鹿田直哉重定直弥近藤亨篠塚琢磨笹井紀明
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] In vitro神経分化システムを用いた領域特異的なグリア細胞の分化誘導2023

    • Author(s)
      篠塚琢磨肥塚梨菜笹井紀明
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] 種特異的な発生時間によって制御される神経管のサイズ2022

    • Author(s)
      笹井 紀明 白井学 篠塚 琢磨 磯谷 綾子
    • Organizer
      第45回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] Species-specific developmental rate determining the size of the vertebrate neural tube2022

    • Author(s)
      Noriaki Sasai, Manabu Shirai, Takuma Shinozuka
    • Organizer
      第45回 日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-21H02889
  • [Presentation] 新規WDドメインタンパク質WDR17の機能解析2022

    • Author(s)
      根本直幸篠塚琢磨笹井紀明
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] 眼の発生に関与する転写因子ネットワークの解析2022

    • Author(s)
      吉永早織山本真帆Agnes Ong Lee Chen笹井紀明
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] マウスES細胞からの領域特異的なグリア細胞の分化誘導2022

    • Author(s)
      篠塚 琢磨笹井 紀明
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] An Essential Role of Polyhomeotic Homolog 1 (Phc1) in Early Neural Development2022

    • Author(s)
      Agnes Ong Lee Chen Manabu Shirai Noriaki Sasai
    • Organizer
      ASCB/EMBO meeting 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] 生物種に特有の神経管サイズを制御する分子メカニズムの解明2020

    • Author(s)
      勝山大暉、白井学、笹井紀明
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] ニワトリ胚神経外植片による脊髄パターン形成の再構築と遺伝子制御ネットワークの解析2020

    • Author(s)
      笹井紀明、作村諭一
    • Organizer
      日本発生生物学会
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] mTORシグナルとソニック・ヘッジホッグシグナルの協調による神経管細胞増殖の制御機構2020

    • Author(s)
      笹井 紀明
    • Organizer
      第93回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Presentation] Reconstituting spinal cord patterning and analyzing the gene regulatory networks by using chick2020

    • Author(s)
      Noriaki Sasai
    • Organizer
      第53回日本発生生物学会
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Presentation] 初期眼発生におけるPHC1の必須の機能2020

    • Author(s)
      Noriaki Sasai
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Presentation] Essential Roles of Polyhomeotic Homolog 1 (Phc1) in Early Retinal Development2020

    • Author(s)
      Agnes Ong Lee Chen, Manabu Shirai, Noriaki Sasai
    • Organizer
      American Society of Cell Biology, ASCB (American Society of cell biology) / EMBO meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] Essential Roles of Polyhomeotic Homolog 1 (Phc1) in Early Retinal Development2020

    • Author(s)
      Noriaki Sasai, Agnes Ong Lee Chen, Manabu Shirai
    • Organizer
      第43回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] 種特異的な神経管サイズを制御する分子メカニズムの解析2020

    • Author(s)
      勝山大暉、白井学、吉鷹玲奈、笹井紀明
    • Organizer
      第42回 日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-18H02786
  • [Presentation] Prominin-1遺伝子の変異による男性不妊のメカニズムの解析2020

    • Author(s)
      吉原えりか、笹井紀明
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H03263
  • [Presentation] GPR17 is an essential regulator for the temporal adaptation of Sonic Hedgehog signaling in neural tube development2019

    • Author(s)
      Atsuki Yatsuzuka, Akiko Hori, Minori Kadoya, Mami Matsuo-Takasaki, Toru Kondo and Noriaki Sasai
    • Organizer
      BSCB/BSDB Joint Annual Spring Meeting 2019
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] Region-specific inactivation of mTOR signal and the regulation of cell proliferation2019

    • Author(s)
      Kadoya Minori, Noriaki Sasai
    • Organizer
      第42回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Presentation] CDK18はGli3のリン酸化を介してSonic Hedgehog経路を調節する2019

    • Author(s)
      西(堀)晶子, 井上亜美, 渡邊仁美, 近藤玄, 廣田圭司, 笹井紀明
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Presentation] Region-specific inactivation of mTOR signal and the regulation of cell proliferation2019

    • Author(s)
      Minori Kadoya, Noriaki Sasai
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] 神経管発生におけるGタンパク共役型受容体GPR17によるSonic Hedgehogシグナルへの負の制御機構2019

    • Author(s)
      八塚敦輝, 西(堀)晶子, 角谷美典, 高崎(松尾)真美, 近藤亨, 笹井紀明
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Presentation] GPR17 is an essential regulator for the temporal adaptation of Sonic Hedgehog signaling in neural tube development2019

    • Author(s)
      Atsuki Yatsuzuka, Akiko Hori, Minori Kadoya, Mami Matsuo-Takasaki, Toru Kondo, Noriaki Sasai
    • Organizer
      BSCB/BSDB Joint Annual Spring Meeting 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Presentation] Region-specific inactivation of mTOR signal and the regulation of cell proliferation2019

    • Author(s)
      Kadoya Minori, Noriaki Sasai
    • Organizer
      第42回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] Polyhomeotic homolog 1 regulates the formation of optic cup-like organoids.2019

    • Author(s)
      Agnes Ong Lee Chen, Manabu Shirai, Noriaki Sasai
    • Organizer
      第41回 日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-18H02786
  • [Presentation] mTORC1 signaling pathway determines the floor plate cell number during the neural tube development2019

    • Author(s)
      Minori Kadoya and Noriaki Sasai
    • Organizer
      BSCB/BSDB Joint Annual Spring Meeting 2019
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] 遺伝性眼疾患の原因遺伝子Prominin-1の解析2019

    • Author(s)
      渡邉静香, 小林由佳, 白井学, 木村和博, 笹井紀明
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] 新規ヘリカーゼ因子ERCC6L2の神経発生における役割の解析2019

    • Author(s)
      小木曽力, 大城樹実, 笹井 紀明
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] ヒト間葉系幹細胞由来神経分化型新規幹細胞の単離と神経障害治療への応用2019

    • Author(s)
      中西徹, 山崎勤, 中野敬介, 長塚仁, 杉野哲造, 笹井紀明
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Presentation] 神経管発生におけるGタンパク共役型受容体GPR17によるSonic Hedgehogシグナルへの負の制御機構2019

    • Author(s)
      八塚敦輝, 西(堀)晶子, 角谷美典, 高崎(松尾)真美, 近藤亨, 笹井紀明
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] ヒト間葉系幹細胞由来神経分化型新規幹細胞の単離と神経障害治療への応用2019

    • Author(s)
      中西徹, 山崎勤, 中野敬介, 長塚仁, 杉野哲造, 笹井紀明
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] The G-protein coupled receptor GPR17 is an essential component of the negative feedback loop of the sonic hedgehog pathway in the neural tube development2019

    • Author(s)
      Atsuki Yatsuzuka, Akiko Hori-Nishi, Minori Kadoya, Toru Kondo and Noriaki Sasai
    • Organizer
      第52回日本発生生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Presentation] Polyhomeotic homolog 1 regulates the formation of optic cup-like organoids2019

    • Author(s)
      Agnes Lee Chen Ong, Manabu Shirai and Noriaki Sasai
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] CDK18はGli3のリン酸化を介してSonic Hedgehog経路を調節する2019

    • Author(s)
      西(堀)晶子, 井上亜美, 渡邊仁美, 近藤玄, 廣田圭司, 笹井紀明
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] 新規ヘリカーゼ因子ERCC6L2の神経発生における役割の解析2019

    • Author(s)
      小木曽力, 大城樹実, 笹井 紀明
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Presentation] Polyhomeotic homolog 1 regulates the formation of optic cup-like organoids2019

    • Author(s)
      Agnes Lee Chen Ong, Manabu Shirai and Noriaki Sasai
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Presentation] The G-protein coupled receptor GPR17 is an essential component of the negative feedback loop of the sonic hedgehog pathway in the neural tube development2019

    • Author(s)
      Atsuki Yatsuzuka, Akiko Hori-Nishi, Minori Kadoya, Toru Kondo and Noriaki Sasai
    • Organizer
      第52回日本発生生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] mTORC1 signaling pathway determines the floor plate cell number during the neural tube development2019

    • Author(s)
      Minori Kadoya and Noriaki Sasai
    • Organizer
      BSCB/BSDB Joint Annual Spring Meeting 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Presentation] Region-specific inactivation of mTOR signal and the regulation of cell proliferation2019

    • Author(s)
      Minori Kadoya, Noriaki Sasai
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Presentation] 遺伝性眼疾患の原因遺伝子Prominin-1の解析2019

    • Author(s)
      渡邉静香, 小林由佳, 白井学, 木村和博, 笹井紀明
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-19H04781
  • [Presentation] GPR17 Is an Essential Component of the Negative Feedback Loop of the Sonic Hedgehog Signalling Pathway in Neural Tube Development2018

    • Author(s)
      Yatsuzuka A, Nishi-Hori A, Kadoya M, Kondo T, Sasai N
    • Organizer
      米国細胞生物学会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] ソニック・ヘッジホッグシグナルによる細胞の増殖・分化制御メカニズム2018

    • Author(s)
      井上 亜美、堀-西 晶子、市川 朋、笹井 紀明
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] PRC関連遺伝子による神経前駆細胞の分化制御2018

    • Author(s)
      豊田 真奈美、白井 学、笹井 紀明
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] 脊椎動物の神経管サイズを決定する分子メカニズム2018

    • Author(s)
      笹井 紀明、吉鷹 玲奈
    • Organizer
      第41回日本分子生物学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19399
  • [Presentation] Prominin-1による細胞突起形成のメカニズム2018

    • Author(s)
      堀-西 晶子、西出 賢次、近藤 亨、笹井 紀明
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] 神経管底板領域に発現するmTORC1の負の制御因子2018

    • Author(s)
      角谷美典、笹井紀明
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] The Novel G-protein coupled receptor GPR17 is the Negative Feedback Loop component of the Sonic Hedgehog Pathway in the Neural Tube Development2018

    • Author(s)
      Atsuki Yatsuzuka, Akiko Hori-Nishi,, Minori Kadoya, Noriaki Sasai
    • Organizer
      第51回日本発生生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] A Screening for the new regulatory pathway of the floor plate differentiation2018

    • Author(s)
      Minori Kadoya, Noriaki Sasai
    • Organizer
      第51回日本発生生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] 眼疾患の原因遺伝子Prominin-1の変異細胞の作製2018

    • Author(s)
      角田 航人、堀-西 晶子、笹井 紀明
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] Induction of Cell membrane protrusions induced by Promimin-12018

    • Author(s)
      Nishi-Hori A, Nishide K, Kondo T, Sasai N.
    • Organizer
      米国細胞生物学会
    • Data Source
      KAKENHI-PROJECT-17H03684
  • [Presentation] 生物種に特有の神経管サイズを制御する分子メカニズム2018

    • Author(s)
      吉鷹 玲奈、笹井 紀明
    • Organizer
      第41回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-17K19399
  • [Presentation] 腹側中枢神経発生の遺伝子ネットワークの解析2015

    • Author(s)
      八塚敦輝、市川朋、安国勇貴、笹井紀明
    • Organizer
      日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15H06411
  • [Presentation] 神経管のパターン形成における時空間の分子制御2015

    • Author(s)
      笹井紀明
    • Organizer
      日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H06411
  • 1.  Bessho Yasumasa (70261253)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  Shirai Manabu (70294121)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 13 results
  • 3.  INOMATA Hidehiko (60372166)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 4.  若林 真樹 (70552024)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  作村 諭一 (50324968)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  松井 貴輝 (60403333)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  磯谷 綾子 (20444523)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 8.  西 晶子 (50772422)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 9.  中畑 泰和 (50390810)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  近藤 亨 (30270573)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  奥崎 大介 (00346131)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  劉 祐誠 (50894698)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  山岸 敬幸 (40255500)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  秋山 隆太郎 (00790403)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  由利 俊祐 (10800881)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  松田 永照 (00335481)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  鳥山 道則
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  鳥山 真奈美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  木村 和博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  小鍛治 俊也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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