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HARUTA Masayuki  春田 雅之

ORCIDConnect your ORCID iD *help
Researcher Number 80392190
Other IDs
Affiliation (Current) 2022: 地方独立行政法人埼玉県立病院機構埼玉県立がんセンター(臨床腫瘍研究所), 臨床腫瘍研究所, 研究員
Affiliation (based on the past Project Information) *help 2016 – 2020: 埼玉県立がんセンター(臨床腫瘍研究所), 臨床腫瘍研究所, 研究員
2012 – 2015: 埼玉県立がんセンター(臨床腫瘍研究所), その他部局等, 研究員
2014: 埼玉県立がんセンター, 臨床腫瘍研究所, 研究員
2013: 埼玉県立がんセンター(臨床腫瘍研究所), 臨床腫瘍研究所, 研究員
2011: 埼玉県立がんセンター, 臨床腫瘍研究所, 研究員
2009 – 2010: Research Institute for Clinical Oncology, Saitama Cancer Center, 臨床腫瘍研究所, 研究員
2006 – 2008: 埼玉県立がんセンター, 臨床腫瘍研究所, 研究員
Review Section/Research Field
Principal Investigator
Pediatrics / Basic Section 50010:Tumor biology-related
Except Principal Investigator
Pediatric surgery / Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords
Principal Investigator
腎芽腫 / WTX / Wilms腫瘍 / 染色体異数性 / 細胞周期制御遺伝子 / エピジェネティックス / DNAメチル化 / 癌 / 遺伝子異常 / βカテニン / 予後因子 / 予後予測因子 / CGH+ SNP array … More
Except Principal Investigator
… More 神経芽腫 / 小児がん / 小児腫瘍学 / 倍数性 / 異数性染色体異常 / 3倍体腫瘍 / 2倍体腫瘍 / 中心体異常 / 3極分裂 / MYCN増幅 / 細胞質不分離 / 倍数性・異数性染色体異常 / 染色体異常 / MYCN / 異数性異常 / 倍数性異常 / M期チェックポイント遺伝子 / 癌幹細胞 / 腫瘍スフェア / 網羅的解析 / 癌 / 遺伝子 / がん幹細胞 / 腎腫瘍 / 腎芽腫 / バイオマーカー / 小児腎腫瘍 / リスク分類 / 白血病 / クロモスリプシス / SNPアレイ / PNA-FISH / 思春期・若年成人 / 次世代シークエンス Less
  • Research Projects

    (9 results)
  • Research Products

    (84 results)
  • Co-Researchers

    (27 People)
  •  小児腎腫瘍(腎芽腫)における11p13-14の新規原因遺伝子同定と機能解析Principal Investigator

    • Principal Investigator
      春田 雅之
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Research Institute for Clinical Oncology, Saitama Cancer Center
  •  思春期若年成人白血病のクロモスリプシスによる悪性化機構解明とゲノム医療への応用

    • Principal Investigator
      川村 眞智子
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Research Institute for Clinical Oncology, Saitama Cancer Center
  •  A novel strategy for pediatric renal tumors using biomarkers as indicators

    • Principal Investigator
      KOSHINAGA Tsugumichi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatric surgery
    • Research Institution
      Nihon University
  •  Analysis of drug-resistant mechanism in nephroblastoma with WTX abnormalityPrincipal Investigator

    • Principal Investigator
      Masayuki Haruta
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Research Institute for Clinical Oncology, Saitama Cancer Center
  •  Development of cancer stem cell-targeted therapy by study of tumor sphere formation mechanism using comprehensive and genetic approach

    • Principal Investigator
      KAMIJO Takehiko
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Research Institute for Clinical Oncology, Saitama Cancer Center
      Chiba Cancer Center (Research Institute)
  •  Establishment of prognostic factor(s) by analysis of genetic abnormality and elucidation of the mechanism of drug resistance in nephroblastomaPrincipal Investigator

    • Principal Investigator
      MASAYUKI Haruta
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Research Institute for Clinical Oncology, Saitama Cancer Center
  •  Analysis of genes involved inβ-catenin degradation in nephroblastomaPrincipal Investigator

    • Principal Investigator
      HARUTA Masayuki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      埼玉県立がんセンター
      Research Institute for Clinical Oncology, Saitama Cancer Center
  •  The mechanism of polyploidy and aneuploidy formation in neuroblastoma

    • Principal Investigator
      KANEKO Yasuhiko
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatric surgery
    • Research Institution
      Research Institute for Clinical Oncology, Saitama Cancer Center
  •  ウイルムス腫瘍における細胞周期制御遺伝子のエピジェネティック異常Principal Investigator

    • Principal Investigator
      春田 雅之
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Research Institute for Clinical Oncology, Saitama Cancer Center

All 2021 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation

  • [Journal Article] Frequent breakpoints of focal deletion and uniparental disomy in 22q11.1 or 11.2 segmental duplication region reveal distinct tumorigenesis in rhabdoid tumor of the kidney2021

    • Author(s)
      Haruta M, Arai Y, Okita H, Tanaka Y, Takimoto T, Kamijo T, Oue T, Souzaki R, Taguchi T, Kuwahara Y, Chin M, Nakadate H, Hiyama E, Ishida Y, Koshinaga T, Kaneko Y.
    • Journal Title

      Genes Chromosomes Cancer.

      Volume: -

    • DOI

      10.1002/gcc.22952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07579
  • [Journal Article] Blastemal predominant type Wilms tumor in Japan: Japan Children's Cancer Group.2019

    • Author(s)
      Koshinaga Tsugumichi、Takimoto Tetsuya、Okita Hajime、Tanaka Yukichi、Inoue Eisuke、Oue Takaharu、Nozaki Miwako、Tsuchiya Kunihiko、Haruta Masayuki、Kaneko Yasuhiko、Fukuzawa Masahiro
    • Journal Title

      Pediatr Int

      Volume: 61 Pages: 351-357

    • DOI

      10.1111/ped.13811

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07822, KAKENHI-PROJECT-19K08310, KAKENHI-PROJECT-17H04356
  • [Journal Article] Paternally inherited WT1 mutation plus uniparental disomy of 11p may be an essential mechanism for development of WT1-mutated familial Wilms tumor.2019

    • Author(s)
      Sato Yuya、Haruta Masayuki、Kaneko Yasuhiko、Nakasato Yoshimasa、Kurosawa Hidemitsu、Yoshihara Shigemi
    • Journal Title

      Pediatric Blood Cancer

      Volume: 66

    • DOI

      10.1002/pbc.27442

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10050, KAKENHI-PROJECT-17H04356
  • [Journal Article] Combined Genetic and Chromosomal Characterization of Wilms Tumors Identifies Chromosome 12 Gain as a Potential New Marker Predicting a Favorable Outcome,2019

    • Author(s)
      Haruta Masayuki、Arai Yasuhito、Okita Hajime、Tanaka Yukichi、Takimoto Tetsuya、Sugino Ryuichi P.、Yamada Yasuhiro、Kamijo Takehiko、Oue Takaharu、Fukuzawa Masahiro、Koshinaga Tsugumichi、Kaneko Yasuhiko
    • Journal Title

      Neoplasia.

      Volume: 21 Pages: 117-131

    • DOI

      10.1016/j.neo.2018.10.007

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01592, KAKENHI-PROJECT-16K08745, KAKENHI-PROJECT-16K10050, KAKENHI-PROJECT-17K19623, KAKENHI-PROJECT-19K08310, KAKENHI-PROJECT-17H04356, KAKENHI-PROJECT-19H03625
  • [Journal Article] Outcome of renal tumors registered in Japan Wilms Tumor Study-2 (JWiTS-2): A report from the Japan Children's Cancer Group (JCCG)2018

    • Author(s)
      Koshinaga Tsugumichi、Takimoto Tetsuya、Oue Takaharu、Okita Hajime、Tanaka Yukichi、Nozaki Miwako、Tsuchiya Kunihiko、Inoue Eisuke、Haruta Masayuki、Kaneko Yasuhiko、Fukuzawa Masahiro
    • Journal Title

      Pediatric Blood & Cancer

      Volume: 65

    • DOI

      10.1002/pbc.27056

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04356, KAKENHI-PROJECT-15K10931, KAKENHI-PROJECT-16K10050
  • [Journal Article] Anaplastic histology Wilms' tumors registered to the Japan Wilms' Tumor Study Group are less aggressive than that in the National Wilms' Tumor Study 52016

    • Author(s)
      Oue T, Koshinaga T, Takimoto T, Okita H, Tanaka Y, Nozaki M, Haruta M, Kaneko Y, Fukuzawa M
    • Journal Title

      Pediatr Surg Int

      Volume: 32 Pages: 851-855

    • DOI

      10.1007/s00383-016-3929-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461600, KAKENHI-PROJECT-16K10050
  • [Journal Article] 分子生物学の新知見2016

    • Author(s)
      春田雅之,上條岳彦
    • Journal Title

      小児外科

      Volume: 48 Pages: 1129-1132

    • Data Source
      KAKENHI-PROJECT-26461600
  • [Journal Article] Management of pediatric renal tumor: Past and future trials of the Japan Wilms Tumor Study Group.2015

    • Author(s)
      Oue T, Fukuzawa M, Koshinaga T, Okita H, Nozaki M, Chin M, Kaneko Y, Tanaka Y, Haruta M, Tsuchiya K, Kuwashima S, Takimoto T.
    • Journal Title

      Pediatr Int.

      Volume: 57 Pages: 828-31

    • DOI

      10.1111/ped.12787

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Journal Article] A high incidence of WT1 abnormality in bilateral Wilms tumours in Japan, and the penetrance rates in children with WT1 germline mutation.2015

    • Author(s)
      Kaneko Y, Okita H, Haruta M, Arai Y, Oue T, Tanaka Y, Horie H, Hinotsu S, Koshinaga T, Yoneda A, Ohtsuka Y, Taguchi T, Fukuzawa M.
    • Journal Title

      Br J Cancer

      Volume: 112 Pages: 1121-1133

    • DOI

      10.1038/bjc.2015.13

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Journal Article] RASSF1A methylation may have two biological roles in neuroblastoma tumorigenesis depending on the ploidy status and age of patients.2014

    • Author(s)
      Haruta M, Kamijo T, Nakagawara A, Kaneko Y
    • Journal Title

      Cancer lett.

      Volume: 348 Pages: 167-176

    • DOI

      10.1016/j.canlet.2014.03.022

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23390405, KAKENHI-PROJECT-24249061, KAKENHI-PROJECT-24390269, KAKENHI-PROJECT-24791099, KAKENHI-PROJECT-25253095
  • [Journal Article] RASSF1A methylation may have two biological roles in neuroblastoma tumorigenesis depending on the ploidy status and age of patients.2014

    • Author(s)
      Haruta M, Kamijo T, Nakagawara A, Kaneko Y.
    • Journal Title

      Cancer Lett.

      Volume: 348 Pages: 167-76

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Journal Article] RASSF1A methylation may have two biological roles in neuroblastoma tumorigenesis depending on the ploidy status and age of patients2014

    • Author(s)
      Haruta M, Kamijo T, Nakagawara A, Kaneko Y
    • Journal Title

      Cancer lett

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791099
  • [Journal Article] Meiosis error and subsequent genetic and epigenetic alterations invoke the malignant transformation of germ cell tumor2013

    • Author(s)
      Kaneko Y, Ichikawa M, Arai Y, Haruta M, Furukawa S, Ariga T, Kajii T
    • Journal Title

      Genes Chromosomes Cancer

      Volume: 52 Pages: 274-286

    • DOI

      10.1002/gcc.22027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390405, KAKENHI-PROJECT-24791099
  • [Journal Article] RASSF1A methylation indicates a poor prognosis in hepatoblastoma patients.2013

    • Author(s)
      Honda S, Miyagi H, Suzuki H, Minato M, Haruta M, Kaneko Y, Hatanaka KC, Hiyama E, Kamijo T, Okada T, Taketomi A
    • Journal Title

      Pediatr Surg Int.

      Volume: 29 Pages: 1147-1152

    • DOI

      10.1007/s00383-013-3371-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23256006, KAKENHI-PROJECT-23390405, KAKENHI-PROJECT-24249084, KAKENHI-PROJECT-24390269, KAKENHI-PROJECT-24791099, KAKENHI-PROJECT-24791886, KAKENHI-PROJECT-25293359, KAKENHI-PROJECT-25670743
  • [Journal Article] Methylation of the RASSF1A promoteris predictive of poor outcome among patients with Wilms tumor2012

    • Author(s)
      Ohshima J, Haruta M, Fujiwara Y, WatanabeN, Arai Y, Ariga T, Okita H, Koshinaga T, Oue T, Hinotsu S, Nakadate H, Horie H, Fukuzawa M, Kaneko Y
    • Journal Title

      Pediatr Blood Cancer

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Journal Article] Methylation of the RASSF1A Promoter Is Predictive of Poor Outcome among Patients with Wilms Tumor2012

    • Author(s)
      Ohshima J, Haruta M, Fujiwara W, Watanabe N, Arai Y, Ariga T, Okita H, Koshinaga T, Oue T, Hinotsu S, Nakadate H, Horie H, Fukuzawa M, Kaneko Y
    • Journal Title

      Pediatr Blood Cancer.

      Volume: 59 Pages: 499-505

    • DOI

      10.1002/pbc.24093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249085, KAKENHI-PROJECT-21791021, KAKENHI-PROJECT-23390405, KAKENHI-PROJECT-23592629, KAKENHI-PROJECT-24791099
  • [Journal Article] Different incidences of epigenetic but not genetic abnormalities between Wilms tumors in Japanese and Caucasian children.2012

    • Author(s)
      Haruta M., et.al.
    • Journal Title

      Cancer Sci.

      Volume: (In press) Pages: 1129-35

    • DOI

      10.1111/j.1349-7006.2012.02269.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791021, KAKENHI-PROJECT-24791099
  • [Journal Article] Genome-wide analysis of allelic imbalances reveals 4q deletions as a poor prognostic factor and MDM4 amplification at 1q32.1 in hepatoblastoma2010

    • Author(s)
      Arai Y, Honda S, Haruta M, Kasai F, Fujiwara Y, Ohshima J, Sasaki F, Nakagawara A, Horie H, Yamaoka H, Hiyama E, Kaneko Y.
    • Journal Title

      Genes Chromosomes Cancer

      Volume: 49 Pages: 596-609

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Journal Article] 小児腫瘍から学ぶ臓器形成におけるWntシグナリングの重要性2010

    • Author(s)
      金子安比古,春田雅之
    • Journal Title

      小児がん

      Volume: 47 Pages: 252-6

    • Data Source
      KAKENHI-PROJECT-21791021
  • [Journal Article] 小児腫瘍から学ぶ臓器形成におけるWntシグナリングの重要性2010

    • Author(s)
      金子安比古、春田雅之
    • Journal Title

      小児がん

      Volume: 47 Pages: 252-256

    • Data Source
      KAKENHI-PROJECT-21791021
  • [Journal Article] Genome wide analysis of allelic imbalances reveals 4q deletions as a poor prognostic factor and MDM4 amplification at 1q32.1 in hepatoblastoma2010

    • Author(s)
      Arai Y, Honsa S, Haruta M, et.al.
    • Journal Title

      Genes Chromosomes Cancer

      Volume: 49 Pages: 596-609

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Journal Article] Genome-wide analysis of allelic imbalances reveals 4q deletions as a poor prognostic factor and MDM4 amplification at 1q32.1 in hepatoblastoma2010

    • Author(s)
      Arai Y, Honsa S, Haruta M, et. al.
    • Journal Title

      Genes Chromosomes Cancer 49

      Pages: 596-609

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Journal Article] Wilms腫瘍の分子生物学:最新の知見2009

    • Author(s)
      金子安比古,春田雅之
    • Journal Title

      小児がん

      Volume: 46 Pages: 282-6

    • NAID

      110007359158

    • Data Source
      KAKENHI-PROJECT-21791021
  • [Journal Article] Centrosome amplification is correlated with ploidy divergence, but not with MYCN amplification in neuroblastoma tumors2009

    • Author(s)
      Fukushi D, Watanabe N, Kasai F, Haruta M, Kikuchi A, Kikuta A, Kato K, Nakadate H, Tsunematsu Y, Kaneko Y
    • Journal Title

      Cancer Genet Cytogenet 188

      Pages: 32-41

    • Data Source
      KAKENHI-PROJECT-18390475
  • [Journal Article] Two candidate tumor suppressor genes, MEOX2 and SOSTDC1, identified in a 7p21 homozygous deletion region in a Wilms tumor.2009

    • Author(s)
      Ohshima J, Haruta M, et. al
    • Journal Title

      Genes Chromosomes Cancer 48

      Pages: 1037-1050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Journal Article] Two candidate tumor suppressor genes, MEOX2 and SOSTDC1, identified in a 7p21 homozygous deletion region in a Wilm stumor2009

    • Author(s)
      Ohshima J, Haruta M, Arai Y, Kasai F, Fujiwara Y, Ariga T, Okita H, Fukuzawa M, Hata J, Horie H, Kaneko Y
    • Journal Title

      Genes Chromosomes Cancer

      Volume: 48 Pages: 1037-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Journal Article] The methylation status of RASSF1A promoter predicts responsiveness to chemotherapy and eventual cure in hepatoblastoma patients.2008

    • Author(s)
      Honda S, Haruta M, Sugawara W, Sasaki F, Ohira M, Matsunaga T, Yamaoka H, Horie H, Ohnuma N, Nakagawara A, Hjyama E, Todo S, Kaneko Y.
    • Journal Title

      Int.J.Cancer, (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390475
  • [Journal Article] Duplication of paternal IGF2 or loss of maternal IGF2 imprinting occurs in half of Wilms tumors with various structural WT1Abnormalities.2008

    • Author(s)
      Haruta M, Arai Y, Sugawara W, Watanabe N, Honda S, Ohshima J, Soejima H, Nakadate H, Okita H, Hata H, Fukuzawa M, Kaneko Y
    • Journal Title

      Chromosomes Cancer (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390475
  • [Journal Article] Combhled BubR1 protein down-regulation and RASSF1A hypermethylation in Wilms tumors with diverse cytogenetic changes.2008

    • Author(s)
      Haruta M, Matsumoto Y, Izumi H, Watanabe N, Fukuzawa M, Matsuura S, Kaneko Y.
    • Journal Title

      Mol Carcinog, (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390475
  • [Journal Article] Promoter hypermethylation of the RASSF1A gene predicts the poor outcome of patients with hepatoblastoma2007

    • Author(s)
      Sugawara W, Haruta M, Sasaki F, Watanabe N, Tsunematsu Y, Kikuta, A, Kaneko Y.
    • Journal Title

      Pediatr Blood & Cancer 49

      Pages: 240-249

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390475
  • [Journal Article] Duplication of the paternal IGF2 allele in trisomy 11 and elevated expression levels of IGF2 mRNA in congenitat mesoblastic nephroma of the cellular ormixed type.2007

    • Author(s)
      Watanabe N, Haruta M, et. al.
    • Journal Title

      Genes Chromosomes Cancer 46

      Pages: 929-935

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18790745
  • [Journal Article] Duplieation of the paternal IGF2 allele in trisomy 11 and elevated expression levels of IGF2 mRNA in congenital mesoblastic nephrqma of the cellular or mixed type.2007

    • Author(s)
      Watanabe N, Haruta M, Soejima H, Fukushi D, Yokomori K, Nakadate H, Okita H, Hata JI, Fukuzawa M, Kaneko Y
    • Journal Title

      Genes Chromosomes Cancer 46

      Pages: 929-935

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390475
  • [Journal Article] Promoter hypermethylation of the RASSFLA gene predicts the poor outcome of patients with hepatomlastoma2006

    • Author(s)
      Sugawara W, Haruta M, et al.
    • Journal Title

      Pediatric Blood & Cancer (in press)

    • Data Source
      KAKENHI-PROJECT-18790745
  • [Journal Article] Assosiation of 11q loss, trisomy 12 and possible 16q loss with loss of imprinting of insulin-like growth gactor-II in wilms tumor2006

    • Author(s)
      Watanabe N, Nakadate H, Haruta M, et al.
    • Journal Title

      Genes Chromosomes Cancer 45

      Pages: 592-601

    • Data Source
      KAKENHI-PROJECT-18790745
  • [Journal Article] Association of 11q loss, trisomy 12 and prossible 16q loss with loss of imprinting of insulin-like growth factor-II in wilms tumor.2006

    • Author(s)
      Watanabe N, Nakadate H, Haruta M, Sugawara W, Sasaki F, Tsunematsu Y, Kikuta A, Fukuzawa M, Okita H, Hata J, Hidenobu H, Kaneko Y
    • Journal Title

      Genes Chromosomes Cancer 45

      Pages: 592-601

    • Data Source
      KAKENHI-PROJECT-18390475
  • [Journal Article] Promoter hypermethylation of the RASSF1A gene predicts the poor outcome of patients with hepatoblastoma.2006

    • Author(s)
      Sugawara W, Haruta M, Sasaki F, Watanabe N, Tsunematsu Y, Kikuta A, Kaneko Y
    • Journal Title

      Pediatr Blood & Cancer (in press)

    • Data Source
      KAKENHI-PROJECT-18390475
  • [Journal Article] Down-regulation of BubR1 protein expression and promoter hypermethylationof RASSF1A in Wilms tumors with diverse cytogenetic changes.

    • Author(s)
      Haruta M, et. al.
    • Journal Title

      Molecular Carcinogenesis In press.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18790745
  • [Journal Article] Duplication of paternal IGF2 or loss of maternal IGF2 imprinting occurs in half of Wilms tumors with various structural WTI abnormalities.

    • Author(s)
      Haruta M, et. al.
    • Journal Title

      Genes Chromosomes Cancer In press.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18790745
  • [Journal Article] Association of germline or somatic TP53 missense mutation with oncogene amplification in tumors developed inpatients with Li-Fraumeni or Li-Fraumeni-like syndrome

    • Author(s)
      Sugawara W, Arai Y, Kasai F, Fujiwara Y, Haruta M
    • Journal Title

      Genes Chromosomes Cancer

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Presentation] Chromothripsis and a NUP98 fusion gene observed in an adolescent case with secondary acute myeloid leukemia2019

    • Author(s)
      Kawamura M, Haruta M, Kaneko Y
    • Organizer
      第78回日本癌学会学術集会 (2019.9.28)京都
    • Data Source
      KAKENHI-PROJECT-19K08310
  • [Presentation] 思春期・若年成人の二次性急性白血病の3例の分子遺伝学的解析2019

    • Author(s)
      川村眞智子、春田雅之、金子安比古
    • Organizer
      第61回 日本小児血液・がん学会(2019.11.16)広島
    • Data Source
      KAKENHI-PROJECT-19K08310
  • [Presentation] Genetic and chromosomal characterization defines favorable or unfavorable outcomes in Wilms tumor patients.2018

    • Author(s)
      春田雅之, 新井康仁, 大喜多肇, 上條岳彦, 野崎美和子, 大植孝治, 福澤正洋, 越永従道.
    • Organizer
      第77回日本癌学会総会学術集会, 大阪, 大阪国際会議場, 2018.9.27
    • Data Source
      KAKENHI-PROJECT-17H04356
  • [Presentation] Prognostic Significance of Chromosome Abnormalities in Wilms Tumor may be Causally Related to Upregulation or Downregulation of Genes on Extra Chromosomes or Lost Chromosome Arms.2018

    • Author(s)
      Kaneko Y, Haruta M, Arai Y, Sugino RP, Kamijo T, Okita H, Tanaka T, Takimoto H, Oue T, Nozaki M, M Chin, Fukuzawa M, Koshinaga T.
    • Organizer
      The 50th Congress of International Society of Paediatric Oncology, Kyoto, 京都国際会館, 2018.11.19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04356
  • [Presentation] The lower incidence of Wilms tumor in Japan than in Caucasian countries: Molecular background of the difference.2017

    • Author(s)
      Kaneko Y, Haruta M, Kamijo T, Arai Y, Okita H, Tanaka T, Takimoto H, Nakadate H, Oue T, Nozaki M, M Chin, Koshinaga T, Fukuzawa M.
    • Organizer
      SIOP-RTSG COMMITTEE MEETING
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04356
  • [Presentation] Genetic and chromosomal characterization correlated with favorable or unfavorable outcomes in Wilms Tumor2017

    • Author(s)
      Masayuki Haruta, Yasuhito Arai, Hajime Okita, Yukichi Tanaka, Tetsuya Takimoto, Ryuichi P. Sugino, Miwako Nozaki, Takaharu Oue, Takehiko Kamijo, Tsugumichi Koshinaga, Masahiro Fukuzawa, and Yasuhiko Kaneko
    • Organizer
      第59回日本小児血液・がん学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04356
  • [Presentation] Pathological analysis of the Renal tumors Registered to the Japan Wilms Tumor Study Group2017

    • Author(s)
      Okita H, Tanaka T, Kaneko Y, Haruta M, Kamijo T, Arai Y, Takimoto H, Nakadate H, Oue T, Nozaki M, M Chin, Koshinaga T, Fukuzawa M.
    • Organizer
      SIOP-RTSG COMMITTEE MEETING
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04356
  • [Presentation] Results of genetic analysis of Wilms tumors registered in JWiTS.2016

    • Author(s)
      Oue T, Haruta M, Kaneko Y.
    • Organizer
      SIOP-RTSG COMMITTEE MEETING.
    • Place of Presentation
      Tubingen
    • Year and Date
      2016-06-10
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Presentation] Characteristics of the Anaplastic Histology Wilms’ Tumors Registered to the Japan Wilms’ Tumor Study Group.2016

    • Author(s)
      Oue T, Koshinaga T, Takimoto T, Okita H, Tanaka Y, Nozaki M, Haruta M, Kaneko Y, Fukuzawa M.
    • Organizer
      48th Annual Congress of the International Society of Paediatric Oncology.
    • Place of Presentation
      Dublin
    • Year and Date
      2016-10-19
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Presentation] 22q uniparental disomyを伴うSMARCB1遺伝子変異の頻度は欧米人の腎または脳ラブドイド腫瘍より日本人の腎ラブドイド腫瘍に高い2016

    • Author(s)
      金子 安比古, 春田 雅之, 上條 岳彦、新井 康仁, 大喜多 肇, 陳 基明, 大植 孝治, 越永 従道, 福澤 正洋
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Presentation] Trisomy 12 occurs before alteration of IGF2 expression and predicts favorable outcome in patients with Wilms tumors.2016

    • Author(s)
      Kaneko Y, Haruta M, Kamijo T, Arai Y, Okita H, Tanaka T, Takimoto H, Nakadate H, Oue T, Nozaki M, M Chin, Koshinaga T, Fukuzawa M.
    • Organizer
      48th Annual Congress of the International Society of Paediatric Oncology.
    • Place of Presentation
      Dublin
    • Year and Date
      2016-10-19
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Presentation] 術前化学療法を受けたtriple-negative乳癌患者の予後はBRCA1ゲノム・エピゲノム異常の有無に左右される2015

    • Author(s)
      金子安比古、高田護、 永井成勲、春田雅之、 戸塚勝理、 武井寛幸、井上賢一、黒住昌史、宮崎勝、 佐藤悠佑、 小川誠司
    • Organizer
      第74回日本癌学会学術集会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Presentation] SIX1/2, DROSHAおよびDGCR8遺伝子変異でなくWTX遺伝子変異はWilms腫瘍の予後因子である2015

    • Author(s)
      春田雅之、新井 康仁、大喜多 肇、大植 孝治、野崎 美和子、越永 従道、福澤 正洋、上條 岳彦、金子 安比古
    • Organizer
      第74回日本癌学会学術集会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Presentation] Relationships between genetic and chromosomal alterations and outcomes in Japanese Wilms tumor patients2015

    • Author(s)
      春田雅之, 大島淳二郎, 新井康仁, 大喜多肇, 大植孝治, 田中祐吉, 野崎美和子, 瀧本哲也, 越永従道, 福澤正洋, 上條岳彦, 金子安比古
    • Organizer
      第57回日本小児血液・がん学会学術集会
    • Place of Presentation
      甲府富士屋ホテル
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Presentation] Polycomb member proteins are new target of anti-neuroblastoma therapy2015

    • Author(s)
      力石浩志、秋田直洋、春田雅之、大平美紀、竹信尚典、古関明彦、上條岳彦
    • Organizer
      第57回日本小児血液・がん学会学術集会
    • Place of Presentation
      甲府富士屋ホテル
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Presentation] ポリコーム群タンパク質L3MBTL2はBMI1と協調的に腫瘍細胞死を抑制する2015

    • Author(s)
      力石 浩志、秋田直洋、春田雅之、大平美紀、竹信尚典、古関明彦、上條岳彦
    • Organizer
      第74回日本癌学会学術集会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Presentation] 神経芽腫のがん幹細胞性を制御する経路の探索2015

    • Author(s)
      竹信尚典、大平美紀、力石 浩志、秋田直洋、 山口 (末永) 陽子、春田雅之、古関明彦、上條岳彦
    • Organizer
      第74回日本癌学会学術集会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Presentation] WTX 遺伝子変異は腎芽腫の予後予測因子である2012

    • Author(s)
      春田雅之, 他
    • Organizer
      第54回日本小児血液・がん学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24791099
  • [Presentation] WTX mutation is a new prognostic factor for Wilms tumor2012

    • Author(s)
      Haruta M, et. Al
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24791099
  • [Presentation] WTX mutation is a new prognostic factor for Wilms tumor.2012

    • Author(s)
      Haruta M, et. al.
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24791099
  • [Presentation] WTX遺伝子変異は腎芽腫の予後予測因子である2012

    • Author(s)
      春田雅之 他
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24791099
  • [Presentation] がん抑制遺伝子RASSF1Aのプロモーターメチル化はWilms腫瘍の予後不良因子である2011

    • Author(s)
      大島淳二,郎春田雅之, 他
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Presentation] The different incidence rate of Wilms in races profoundly contributes to IGF2LOI, but not abnormality of WT1, WTX and CTNNB1.2010

    • Author(s)
      Haruta M, et.al.
    • Organizer
      AACR 101^<st> Annual Meeting
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Presentation] HER2 genomic copy mumber predicts response to trastuzumab-combined chemotherapy better than HER2 immunohistochemistry.2010

    • Author(s)
      Higuchi T, Kasai F, Haruta M, et.al.
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Presentation] SNP array patterns in Wilms tumors with the possibility of abnormalities of unknown genes responsible for tomorigenesis2010

    • Author(s)
      Haruta M, et. al
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Presentation] The different incidence rate of Wilms in races profoundly contributes toIGF2 LOI, but not abnormality of WT1, WTX and CTNNB12010

    • Author(s)
      Haruta M, et. Al
    • Organizer
      AACR 101^<st> Annual Meeting
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Presentation] TP53 germeline mutations may induce oncogene amplification in tumors developing in patients with Li-Fraumeni syndrome.2010

    • Author(s)
      Kaneko Y, Arai Y, Kasai F, Haruta M, et.al.
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Presentation] SNPアレイ解析により検出された肝芽腫の4q欠失は予後不良因子である2009

    • Author(s)
      金子安比古、新井康仁、本多昌平、春田雅之, 他
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Presentation] Wilms腫瘍の7p21ホモ欠失領域から同定された候補腫瘍抑制遺伝子MEOX2とSOTDC12009

    • Author(s)
      大島淳二郎、春田雅之, 他
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Presentation] Loss of Heterozygosity Analysis in Wilms Tumor2009

    • Author(s)
      Padilla R, Haruta M, et. al
    • Organizer
      ASHG 59th Annual Meeting
    • Place of Presentation
      Honolulu
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Presentation] ウィルムス腫瘍で初めて同定されたAPC遺伝子変異2009

    • Author(s)
      春田雅之, 他
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Presentation] Wilms腫瘍の7p21ホモ欠失領域から同定された候補腫瘍抑制遺伝子MEOX2とSOTDC12009

    • Author(s)
      大島淳二郎春田雅之, 他
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Presentation] ウィルムス腫瘍で初めて同定されたAPC遺伝子変異2009

    • Author(s)
      春田雅之, 他
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-21791021
  • [Presentation] 乳児と小児2倍体神経芽腫の特徴-中心体の増幅と異数性細胞の混在-2008

    • Author(s)
      笠井文生、福士大輔、渡辺直樹、春田雅之、金子安比古
    • Organizer
      第67回日本癌学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390475
  • [Presentation] Centrosome amplification is correlated with ploidy instability in infant neuroblastoma (NB) tumors, but not with MYCN amplification in infant and childhood NB tumors or cell line2008

    • Author(s)
      Kaneko Y, Fukushi D, Watanabe N, Kasai F, Haruta M, Kikuchi A, Kikuta A, Tsunematsu Y
    • Organizer
      Advances in Neuroblastoma Research
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-18390475
  • [Presentation] 神経芽腫のploidy異常の発生に3極分極が関与するのか?2007

    • Author(s)
      福士大輔、渡辺直樹、春田雅之、金子安比古
    • Organizer
      第66回日本癌学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390475
  • [Presentation] Loss of imprinting (LOI) of IGF2was found in a substantial number of Wilms tumors in Japanese children.2007

    • Author(s)
      Haruta M, et. al.
    • Organizer
      American Association for Cancer Research Annual Meeting 2007
    • Place of Presentation
      Los Angels Convention Center
    • Year and Date
      2007-04-15
    • Data Source
      KAKENHI-PROJECT-18790745
  • [Presentation] 神経芽腫のploidy異常の発生に中心体異常は関与するのか?2006

    • Author(s)
      福士大輔、渡辺直樹、春田雅之、金子安比古
    • Organizer
      第22回日本小児がん学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-18390475
  • [Presentation] マススクリ-ニングで発見された神経芽腫におけるアポトーシス関連遺伝子のメチル化異常2006

    • Author(s)
      春田雅之、大平美紀、中川原章、金子安比古
    • Organizer
      第22回日本小児がん学会.
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-18390475
  • [Presentation] RASSF1A遺伝子DNAメチル化は神経芽腫の患者年齢とploidyにより異なる生物学的役割をもつ

    • Author(s)
      春田 雅之、上條 岳彦、中川原 章、金子 安比古
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Presentation] WT1 遺伝子異常タイプとその親由来が遺伝性 Wilms 腫瘍の浸透率に影響する

    • Author(s)
      金子 安比古、大喜多 肇、春田 雅之、新井 康仁、大植 孝治、越永 従道、福澤 正洋
    • Organizer
      第59回日本人類遺伝学会
    • Place of Presentation
      東京
    • Year and Date
      2014-11-19 – 2014-11-22
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Presentation] DNAメチル化解析による肝芽腫の新規予後予測マーカーの確立

    • Author(s)
      本多 昌平、湊 雅嗣、鈴木 拓、春田 雅之、金子 安比古、檜山 英三、武冨 紹信
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Presentation] Parental Inheritance and WT1 Abnormality Types May Affect the Penetrance Rate of Hereditary Wilms Tumor.

    • Author(s)
      Y. Kaneko, H. Okita, M. Haruta, Y. Arai, T. Oue, T. Koshinaga, M. Fukuzawa
    • Organizer
      The 63rd Annual Meeting of the American Society of Human Genetics
    • Place of Presentation
      San Diego
    • Year and Date
      2014-10-18 – 2014-10-22
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Presentation] BRCA1関連ゲノム異常は予後良好トリプルネガティブ乳癌と、BRCA2関連ゲノム異常は予後不良ER陽性乳癌と相関する

    • Author(s)
      金子 安比古、高田 護、春田 雅之、戸塚 勝理、武井 寛幸、永井 成勲、井上 賢一、黒住 昌史、宮崎 勝、佐藤 亜以子、佐藤 悠祐、小川 誠司
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26461600
  • [Presentation] RASSF1A遺伝子DNAメチル化は神経芽腫の患者年齢とploidyにより異なる生物学的役割をもつ

    • Author(s)
      春田 雅之, 上條 岳彦, 中川原 章, 金子 安比古
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24390269
  • 1.  KANEKO Yasuhiko (50373387)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 40 results
  • 2.  KASAI Fumio (60393055)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 3.  FUKUSHI Daisuke (90397159)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 4.  KAMIJO Takehiko (90262708)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 5.  KOSHINAGA Tsugumichi (70205376)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 6.  田尻 達郎 (80304806)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  吉田 英生 (60210712)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  竹信 尚典 (60392247)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  野崎 美和子 (10175523)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  瀧本 哲也 (40393178)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 11.  陳 基明 (50277422)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 12.  大植 孝治 (50314315)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 13.  大喜多 肇 (50317260)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 14.  井上 永介 (50528338)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 15.  谷ヶ崎 博 (90378141)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  安藤 清宏 (10455389)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  川村 眞智子 (80450592)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 18.  小林 泰文 (50455375)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  KANEKO Michio
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  FUKUZAWA Masahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  Yamada Yasuhiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  HONDA Shohei
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  中川原 章
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  滝 智彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 25.  桧山 英三
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  田中 祐吉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  田中 水緒
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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