HARUTA Masayuki 春田雅之

Researcher Number	80392190
Other IDs
Affiliation (Current)	2022: 地方独立行政法人埼玉県立病院機構埼玉県立がんセンター(臨床腫瘍研究所), 臨床腫瘍研究所, 研究員
Affiliation (based on the past Project Information) *help	2016 – 2020: 埼玉県立がんセンター(臨床腫瘍研究所), 臨床腫瘍研究所, 研究員 2012 – 2015: 埼玉県立がんセンター(臨床腫瘍研究所), その他部局等, 研究員 2014: 埼玉県立がんセンター, 臨床腫瘍研究所, 研究員 2013: 埼玉県立がんセンター(臨床腫瘍研究所), 臨床腫瘍研究所, 研究員 2011: 埼玉県立がんセンター, 臨床腫瘍研究所, 研究員 2009 – 2010: Research Institute for Clinical Oncology, Saitama Cancer Center, 臨床腫瘍研究所, 研究員 2006 – 2008: 埼玉県立がんセンター, 臨床腫瘍研究所, 研究員
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 50010:Tumor biology-related Except Principal Investigator Pediatric surgery / Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator 腎芽腫 / WTX / Wilms腫瘍 / 染色体異数性 / 細胞周期制御遺伝子 / エピジェネティックス / DNAメチル化 / 癌 / 遺伝子異常 / βカテニン / 予後因子 / 予後予測因子 / CGH＋ SNP array … More Except Principal Investigator … More

小児腎腫瘍（腎芽腫）における11p13-14の新規原因遺伝子同定と機能解析Principal Investigator
- Principal Investigator
  
  春田雅之
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
思春期若年成人白血病のクロモスリプシスによる悪性化機構解明とゲノム医療への応用
- Principal Investigator
  
  川村眞智子
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
A novel strategy for pediatric renal tumors using biomarkers as indicators
- Principal Investigator
  
  KOSHINAGA Tsugumichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatric surgery
- Research Institution
  Nihon University
Analysis of drug-resistant mechanism in nephroblastoma with WTX abnormalityPrincipal Investigator
- Principal Investigator
  
  Masayuki Haruta
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
Development of cancer stem cell-targeted therapy by study of tumor sphere formation mechanism using comprehensive and genetic approach
- Principal Investigator
  
  KAMIJO Takehiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
  Chiba Cancer Center (Research Institute)
Establishment of prognostic factor(s) by analysis of genetic abnormality and elucidation of the mechanism of drug resistance in nephroblastomaPrincipal Investigator
- Principal Investigator
  
  MASAYUKI Haruta
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
Analysis of genes involved inβ-catenin degradation in nephroblastomaPrincipal Investigator
- Principal Investigator
  
  HARUTA Masayuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  埼玉県立がんセンター
   Research Institute for Clinical Oncology, Saitama Cancer Center
The mechanism of polyploidy and aneuploidy formation in neuroblastoma
- Principal Investigator
  
  KANEKO Yasuhiko
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatric surgery
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
ウイルムス腫瘍における細胞周期制御遺伝子のエピジェネティック異常Principal Investigator
- Principal Investigator
  
  春田雅之
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center

[Journal Article] Frequent breakpoints of focal deletion and uniparental disomy in 22q11.1 or 11.2 segmental duplication region reveal distinct tumorigenesis in rhabdoid tumor of the kidney2021
- Author(s)
  Haruta M, Arai Y, Okita H, Tanaka Y, Takimoto T, Kamijo T, Oue T, Souzaki R, Taguchi T, Kuwahara Y, Chin M, Nakadate H, Hiyama E, Ishida Y, Koshinaga T, Kaneko Y.
- Journal Title
  
  Genes Chromosomes Cancer.
  
  Volume: -
- DOI
  10.1002/gcc.22952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07579
[Journal Article] Blastemal predominant type Wilms tumor in Japan: Japan Children's Cancer Group.2019
- Author(s)
  Koshinaga Tsugumichi、Takimoto Tetsuya、Okita Hajime、Tanaka Yukichi、Inoue Eisuke、Oue Takaharu、Nozaki Miwako、Tsuchiya Kunihiko、Haruta Masayuki、Kaneko Yasuhiko、Fukuzawa Masahiro
- Journal Title
  
  Pediatr Int
  
  Volume: 61 Pages: 351-357
- DOI
  10.1111/ped.13811
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07822, KAKENHI-PROJECT-19K08310, KAKENHI-PROJECT-17H04356
[Journal Article] Paternally inherited WT1 mutation plus uniparental disomy of 11p may be an essential mechanism for development of WT1-mutated familial Wilms tumor.2019
- Author(s)
  Sato Yuya、Haruta Masayuki、Kaneko Yasuhiko、Nakasato Yoshimasa、Kurosawa Hidemitsu、Yoshihara Shigemi
- Journal Title
  
  Pediatric Blood Cancer
  
  Volume: 66
- DOI
  10.1002/pbc.27442
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10050, KAKENHI-PROJECT-17H04356
[Journal Article] Combined Genetic and Chromosomal Characterization of Wilms Tumors Identifies Chromosome 12 Gain as a Potential New Marker Predicting a Favorable Outcome,2019
- Author(s)
  Haruta Masayuki、Arai Yasuhito、Okita Hajime、Tanaka Yukichi、Takimoto Tetsuya、Sugino Ryuichi P.、Yamada Yasuhiro、Kamijo Takehiko、Oue Takaharu、Fukuzawa Masahiro、Koshinaga Tsugumichi、Kaneko Yasuhiko
- Journal Title
  
  Neoplasia.
  
  Volume: 21 Pages: 117-131
- DOI
  10.1016/j.neo.2018.10.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01592, KAKENHI-PROJECT-16K08745, KAKENHI-PROJECT-16K10050, KAKENHI-PROJECT-17K19623, KAKENHI-PROJECT-19K08310, KAKENHI-PROJECT-17H04356, KAKENHI-PROJECT-19H03625
[Journal Article] Outcome of renal tumors registered in Japan Wilms Tumor Study-2 (JWiTS-2): A report from the Japan Children's Cancer Group (JCCG)2018
- Author(s)
  Koshinaga Tsugumichi、Takimoto Tetsuya、Oue Takaharu、Okita Hajime、Tanaka Yukichi、Nozaki Miwako、Tsuchiya Kunihiko、Inoue Eisuke、Haruta Masayuki、Kaneko Yasuhiko、Fukuzawa Masahiro
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 65
- DOI
  10.1002/pbc.27056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04356, KAKENHI-PROJECT-15K10931, KAKENHI-PROJECT-16K10050
[Journal Article] Anaplastic histology Wilms' tumors registered to the Japan Wilms' Tumor Study Group are less aggressive than that in the National Wilms' Tumor Study 52016
- Author(s)
  Oue T, Koshinaga T, Takimoto T, Okita H, Tanaka Y, Nozaki M, Haruta M, Kaneko Y, Fukuzawa M
- Journal Title
  
  Pediatr Surg Int
  
  Volume: 32 Pages: 851-855
- DOI
  10.1007/s00383-016-3929-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461600, KAKENHI-PROJECT-16K10050
[Journal Article] 分子生物学の新知見2016
- Author(s)
  春田雅之,上條岳彦
- Journal Title
  
  小児外科
  
  Volume: 48 Pages: 1129-1132
- Data Source
  KAKENHI-PROJECT-26461600
[Journal Article] Management of pediatric renal tumor: Past and future trials of the Japan Wilms Tumor Study Group.2015
- Author(s)
  Oue T, Fukuzawa M, Koshinaga T, Okita H, Nozaki M, Chin M, Kaneko Y, Tanaka Y, Haruta M, Tsuchiya K, Kuwashima S, Takimoto T.
- Journal Title
  
  Pediatr Int.
  
  Volume: 57 Pages: 828-31
- DOI
  10.1111/ped.12787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461600
[Journal Article] A high incidence of WT1 abnormality in bilateral Wilms tumours in Japan, and the penetrance rates in children with WT1 germline mutation.2015
- Author(s)
  Kaneko Y, Okita H, Haruta M, Arai Y, Oue T, Tanaka Y, Horie H, Hinotsu S, Koshinaga T, Yoneda A, Ohtsuka Y, Taguchi T, Fukuzawa M.
- Journal Title
  
  Br J Cancer
  
  Volume: 112 Pages: 1121-1133
- DOI
  10.1038/bjc.2015.13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461600
[Journal Article] RASSF1A methylation may have two biological roles in neuroblastoma tumorigenesis depending on the ploidy status and age of patients.2014
- Author(s)
  Haruta M, Kamijo T, Nakagawara A, Kaneko Y
- Journal Title
  
  Cancer lett.
  
  Volume: 348 Pages: 167-176
- DOI
  10.1016/j.canlet.2014.03.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390405, KAKENHI-PROJECT-24249061, KAKENHI-PROJECT-24390269, KAKENHI-PROJECT-24791099, KAKENHI-PROJECT-25253095
[Journal Article] RASSF1A methylation may have two biological roles in neuroblastoma tumorigenesis depending on the ploidy status and age of patients.2014
- Author(s)
  Haruta M, Kamijo T, Nakagawara A, Kaneko Y.
- Journal Title
  
  Cancer Lett.
  
  Volume: 348 Pages: 167-76
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461600
[Journal Article] RASSF1A methylation may have two biological roles in neuroblastoma tumorigenesis depending on the ploidy status and age of patients2014
- Author(s)
  Haruta M, Kamijo T, Nakagawara A, Kaneko Y
- Journal Title
  
  Cancer lett
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791099
[Journal Article] Meiosis error and subsequent genetic and epigenetic alterations invoke the malignant transformation of germ cell tumor2013
- Author(s)
  Kaneko Y, Ichikawa M, Arai Y, Haruta M, Furukawa S, Ariga T, Kajii T
- Journal Title
  
  Genes Chromosomes Cancer
  
  Volume: 52 Pages: 274-286
- DOI
  10.1002/gcc.22027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390405, KAKENHI-PROJECT-24791099
[Journal Article] RASSF1A methylation indicates a poor prognosis in hepatoblastoma patients.2013
- Author(s)
  Honda S, Miyagi H, Suzuki H, Minato M, Haruta M, Kaneko Y, Hatanaka KC, Hiyama E, Kamijo T, Okada T, Taketomi A
- Journal Title
  
  Pediatr Surg Int.
  
  Volume: 29 Pages: 1147-1152
- DOI
  10.1007/s00383-013-3371-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23256006, KAKENHI-PROJECT-23390405, KAKENHI-PROJECT-24249084, KAKENHI-PROJECT-24390269, KAKENHI-PROJECT-24791099, KAKENHI-PROJECT-24791886, KAKENHI-PROJECT-25293359, KAKENHI-PROJECT-25670743
[Journal Article] Methylation of the RASSF1A promoteris predictive of poor outcome among patients with Wilms tumor2012
- Author(s)
  Ohshima J, Haruta M, Fujiwara Y, WatanabeN, Arai Y, Ariga T, Okita H, Koshinaga T, Oue T, Hinotsu S, Nakadate H, Horie H, Fukuzawa M, Kaneko Y
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791021
[Journal Article] Methylation of the RASSF1A Promoter Is Predictive of Poor Outcome among Patients with Wilms Tumor2012
- Author(s)
  Ohshima J, Haruta M, Fujiwara W, Watanabe N, Arai Y, Ariga T, Okita H, Koshinaga T, Oue T, Hinotsu S, Nakadate H, Horie H, Fukuzawa M, Kaneko Y
- Journal Title
  
  Pediatr Blood Cancer.
  
  Volume: 59 Pages: 499-505
- DOI
  10.1002/pbc.24093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249085, KAKENHI-PROJECT-21791021, KAKENHI-PROJECT-23390405, KAKENHI-PROJECT-23592629, KAKENHI-PROJECT-24791099
[Journal Article] Different incidences of epigenetic but not genetic abnormalities between Wilms tumors in Japanese and Caucasian children.2012
- Author(s)
  Haruta M., et.al.
- Journal Title
  
  Cancer Sci.
  
  Volume: (In press) Pages: 1129-35
- DOI
  10.1111/j.1349-7006.2012.02269.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791021, KAKENHI-PROJECT-24791099
[Journal Article] Genome-wide analysis of allelic imbalances reveals 4q deletions as a poor prognostic factor and MDM4 amplification at 1q32.1 in hepatoblastoma2010
- Author(s)
  Arai Y, Honda S, Haruta M, Kasai F, Fujiwara Y, Ohshima J, Sasaki F, Nakagawara A, Horie H, Yamaoka H, Hiyama E, Kaneko Y.
- Journal Title
  
  Genes Chromosomes Cancer
  
  Volume: 49 Pages: 596-609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791021
[Journal Article] 小児腫瘍から学ぶ臓器形成におけるWntシグナリングの重要性2010
- Author(s)
  金子安比古,春田雅之
- Journal Title
  
  小児がん
  
  Volume: 47 Pages: 252-6
- Data Source
  KAKENHI-PROJECT-21791021
[Journal Article] 小児腫瘍から学ぶ臓器形成におけるWntシグナリングの重要性2010
- Author(s)
  金子安比古、春田雅之
- Journal Title
  
  小児がん
  
  Volume: 47 Pages: 252-256
- Data Source
  KAKENHI-PROJECT-21791021
[Journal Article] Genome wide analysis of allelic imbalances reveals 4q deletions as a poor prognostic factor and MDM4 amplification at 1q32.1 in hepatoblastoma2010
- Author(s)
  Arai Y, Honsa S, Haruta M, et.al.
- Journal Title
  
  Genes Chromosomes Cancer
  
  Volume: 49 Pages: 596-609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791021
[Journal Article] Genome-wide analysis of allelic imbalances reveals 4q deletions as a poor prognostic factor and MDM4 amplification at 1q32.1 in hepatoblastoma2010
- Author(s)
  Arai Y, Honsa S, Haruta M, et. al.
- Journal Title
  
  Genes Chromosomes Cancer 49
  
  Pages: 596-609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791021
[Journal Article] Wilms腫瘍の分子生物学:最新の知見2009
- Author(s)
  金子安比古,春田雅之
- Journal Title
  
  小児がん
  
  Volume: 46 Pages: 282-6
- NAID
  110007359158
- Data Source
  KAKENHI-PROJECT-21791021
[Journal Article] Centrosome amplification is correlated with ploidy divergence, but not with MYCN amplification in neuroblastoma tumors2009
- Author(s)
  Fukushi D, Watanabe N, Kasai F, Haruta M, Kikuchi A, Kikuta A, Kato K, Nakadate H, Tsunematsu Y, Kaneko Y
- Journal Title
  
  Cancer Genet Cytogenet 188
  
  Pages: 32-41
- Data Source
  KAKENHI-PROJECT-18390475
[Journal Article] Two candidate tumor suppressor genes, MEOX2 and SOSTDC1, identified in a 7p21 homozygous deletion region in a Wilms tumor.2009
- Author(s)
  Ohshima J, Haruta M, et. al
- Journal Title
  
  Genes Chromosomes Cancer 48
  
  Pages: 1037-1050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791021
[Journal Article] Two candidate tumor suppressor genes, MEOX2 and SOSTDC1, identified in a 7p21 homozygous deletion region in a Wilm stumor2009
- Author(s)
  Ohshima J, Haruta M, Arai Y, Kasai F, Fujiwara Y, Ariga T, Okita H, Fukuzawa M, Hata J, Horie H, Kaneko Y
- Journal Title
  
  Genes Chromosomes Cancer
  
  Volume: 48 Pages: 1037-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791021
[Journal Article] The methylation status of RASSF1A promoter predicts responsiveness to chemotherapy and eventual cure in hepatoblastoma patients.2008
- Author(s)
  Honda S, Haruta M, Sugawara W, Sasaki F, Ohira M, Matsunaga T, Yamaoka H, Horie H, Ohnuma N, Nakagawara A, Hjyama E, Todo S, Kaneko Y.
- Journal Title
  
  Int.J.Cancer, (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390475
[Journal Article] Duplication of paternal IGF2 or loss of maternal IGF2 imprinting occurs in half of Wilms tumors with various structural WT1Abnormalities.2008
- Author(s)
  Haruta M, Arai Y, Sugawara W, Watanabe N, Honda S, Ohshima J, Soejima H, Nakadate H, Okita H, Hata H, Fukuzawa M, Kaneko Y
- Journal Title
  
  Chromosomes Cancer (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390475
[Journal Article] Combhled BubR1 protein down-regulation and RASSF1A hypermethylation in Wilms tumors with diverse cytogenetic changes.2008
- Author(s)
  Haruta M, Matsumoto Y, Izumi H, Watanabe N, Fukuzawa M, Matsuura S, Kaneko Y.
- Journal Title
  
  Mol Carcinog, (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390475
[Journal Article] Promoter hypermethylation of the RASSF1A gene predicts the poor outcome of patients with hepatoblastoma2007
- Author(s)
  Sugawara W, Haruta M, Sasaki F, Watanabe N, Tsunematsu Y, Kikuta, A, Kaneko Y.
- Journal Title
  
  Pediatr Blood & Cancer 49
  
  Pages: 240-249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390475
[Journal Article] Duplication of the paternal IGF2 allele in trisomy 11 and elevated expression levels of IGF2 mRNA in congenitat mesoblastic nephroma of the cellular ormixed type.2007
- Author(s)
  Watanabe N, Haruta M, et. al.
- Journal Title
  
  Genes Chromosomes Cancer 46
  
  Pages: 929-935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790745
[Journal Article] Duplieation of the paternal IGF2 allele in trisomy 11 and elevated expression levels of IGF2 mRNA in congenital mesoblastic nephrqma of the cellular or mixed type.2007
- Author(s)
  Watanabe N, Haruta M, Soejima H, Fukushi D, Yokomori K, Nakadate H, Okita H, Hata JI, Fukuzawa M, Kaneko Y
- Journal Title
  
  Genes Chromosomes Cancer 46
  
  Pages: 929-935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390475
[Journal Article] Promoter hypermethylation of the RASSFLA gene predicts the poor outcome of patients with hepatomlastoma2006
- Author(s)
  Sugawara W, Haruta M, et al.
- Journal Title
  
  Pediatric Blood ＆ Cancer (in press)
- Data Source
  KAKENHI-PROJECT-18790745
[Journal Article] Assosiation of 11q loss, trisomy 12 and possible 16q loss with loss of imprinting of insulin-like growth gactor-II in wilms tumor2006
- Author(s)
  Watanabe N, Nakadate H, Haruta M, et al.
- Journal Title
  
  Genes Chromosomes Cancer 45
  
  Pages: 592-601
- Data Source
  KAKENHI-PROJECT-18790745
[Journal Article] Association of 11q loss, trisomy 12 and prossible 16q loss with loss of imprinting of insulin-like growth factor-II in wilms tumor.2006
- Author(s)
  Watanabe N, Nakadate H, Haruta M, Sugawara W, Sasaki F, Tsunematsu Y, Kikuta A, Fukuzawa M, Okita H, Hata J, Hidenobu H, Kaneko Y
- Journal Title
  
  Genes Chromosomes Cancer 45
  
  Pages: 592-601
- Data Source
  KAKENHI-PROJECT-18390475
[Journal Article] Promoter hypermethylation of the RASSF1A gene predicts the poor outcome of patients with hepatoblastoma.2006
- Author(s)
  Sugawara W, Haruta M, Sasaki F, Watanabe N, Tsunematsu Y, Kikuta A, Kaneko Y
- Journal Title
  
  Pediatr Blood ＆ Cancer (in press)
- Data Source
  KAKENHI-PROJECT-18390475
[Journal Article] Down-regulation of BubR1 protein expression and promoter hypermethylationof RASSF1A in Wilms tumors with diverse cytogenetic changes.
- Author(s)
  Haruta M, et. al.
- Journal Title
  
  Molecular Carcinogenesis In press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790745
[Journal Article] Duplication of paternal IGF2 or loss of maternal IGF2 imprinting occurs in half of Wilms tumors with various structural WTI abnormalities.
- Author(s)
  Haruta M, et. al.
- Journal Title
  
  Genes Chromosomes Cancer In press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790745
[Journal Article] Association of germline or somatic TP53 missense mutation with oncogene amplification in tumors developed inpatients with Li-Fraumeni or Li-Fraumeni-like syndrome
- Author(s)
  Sugawara W, Arai Y, Kasai F, Fujiwara Y, Haruta M
- Journal Title
  
  Genes Chromosomes Cancer
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791021
[Presentation] Chromothripsis and a NUP98 fusion gene observed in an adolescent case with secondary acute myeloid leukemia2019
- Author(s)
  Kawamura M, Haruta M, Kaneko Y
- Organizer
  第78回日本癌学会学術集会 (2019.9.28)京都
- Data Source
  KAKENHI-PROJECT-19K08310
[Presentation] 思春期・若年成人の二次性急性白血病の3例の分子遺伝学的解析2019
- Author(s)
  川村眞智子、春田雅之、金子安比古
- Organizer
  第61回日本小児血液・がん学会（2019．11.16）広島
- Data Source
  KAKENHI-PROJECT-19K08310
[Presentation] Genetic and chromosomal characterization defines favorable or unfavorable outcomes in Wilms tumor patients.2018
- Author(s)
  春田雅之, 新井康仁, 大喜多肇, 上條岳彦, 野崎美和子, 大植孝治, 福澤正洋, 越永従道.
- Organizer
  第77回日本癌学会総会学術集会, 大阪, 大阪国際会議場, 2018.9.27
- Data Source
  KAKENHI-PROJECT-17H04356
[Presentation] Prognostic Significance of Chromosome Abnormalities in Wilms Tumor may be Causally Related to Upregulation or Downregulation of Genes on Extra Chromosomes or Lost Chromosome Arms.2018
- Author(s)
  Kaneko Y, Haruta M, Arai Y, Sugino RP, Kamijo T, Okita H, Tanaka T, Takimoto H, Oue T, Nozaki M, M Chin, Fukuzawa M, Koshinaga T.
- Organizer
  The 50th Congress of International Society of Paediatric Oncology, Kyoto, 京都国際会館, 2018.11.19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04356
[Presentation] The lower incidence of Wilms tumor in Japan than in Caucasian countries: Molecular background of the difference.2017
- Author(s)
  Kaneko Y, Haruta M, Kamijo T, Arai Y, Okita H, Tanaka T, Takimoto H, Nakadate H, Oue T, Nozaki M, M Chin, Koshinaga T, Fukuzawa M.
- Organizer
  SIOP-RTSG COMMITTEE MEETING
- Invited
- Data Source
  KAKENHI-PROJECT-17H04356
[Presentation] Genetic and chromosomal characterization correlated with favorable or unfavorable outcomes in Wilms Tumor2017
- Author(s)
  Masayuki Haruta, Yasuhito Arai, Hajime Okita, Yukichi Tanaka, Tetsuya Takimoto, Ryuichi P. Sugino, Miwako Nozaki, Takaharu Oue, Takehiko Kamijo, Tsugumichi Koshinaga, Masahiro Fukuzawa, and Yasuhiko Kaneko
- Organizer
  第59回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04356
[Presentation] Pathological analysis of the Renal tumors Registered to the Japan Wilms Tumor Study Group2017
- Author(s)
  Okita H, Tanaka T, Kaneko Y, Haruta M, Kamijo T, Arai Y, Takimoto H, Nakadate H, Oue T, Nozaki M, M Chin, Koshinaga T, Fukuzawa M.
- Organizer
  SIOP-RTSG COMMITTEE MEETING
- Invited
- Data Source
  KAKENHI-PROJECT-17H04356
[Presentation] Results of genetic analysis of Wilms tumors registered in JWiTS.2016
- Author(s)
  Oue T, Haruta M, Kaneko Y.
- Organizer
  SIOP-RTSG COMMITTEE MEETING.
- Place of Presentation
  Tubingen
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-26461600
[Presentation] Characteristics of the Anaplastic Histology Wilms’ Tumors Registered to the Japan Wilms’ Tumor Study Group.2016
- Author(s)
  Oue T, Koshinaga T, Takimoto T, Okita H, Tanaka Y, Nozaki M, Haruta M, Kaneko Y, Fukuzawa M.
- Organizer
  48th Annual Congress of the International Society of Paediatric Oncology.
- Place of Presentation
  Dublin
- Year and Date
  2016-10-19
- Data Source
  KAKENHI-PROJECT-26461600
[Presentation] 22q uniparental disomyを伴うSMARCB1遺伝子変異の頻度は欧米人の腎または脳ラブドイド腫瘍より日本人の腎ラブドイド腫瘍に高い2016
- Author(s)
  金子安比古, 春田雅之, 上條岳彦、新井康仁, 大喜多肇, 陳基明, 大植孝治, 越永従道, 福澤正洋
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26461600
[Presentation] Trisomy 12 occurs before alteration of IGF2 expression and predicts favorable outcome in patients with Wilms tumors.2016
- Author(s)
  Kaneko Y, Haruta M, Kamijo T, Arai Y, Okita H, Tanaka T, Takimoto H, Nakadate H, Oue T, Nozaki M, M Chin, Koshinaga T, Fukuzawa M.
- Organizer
  48th Annual Congress of the International Society of Paediatric Oncology.
- Place of Presentation
  Dublin
- Year and Date
  2016-10-19
- Data Source
  KAKENHI-PROJECT-26461600
[Presentation] 術前化学療法を受けたtriple-negative乳癌患者の予後はBRCA1ゲノム・エピゲノム異常の有無に左右される2015
- Author(s)
  金子安比古、高田護、永井成勲、春田雅之、戸塚勝理、武井寛幸、井上賢一、黒住昌史、宮崎勝、佐藤悠佑、小川誠司
- Organizer
  第74回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26461600
[Presentation] SIX1/2, DROSHAおよびDGCR8遺伝子変異でなくWTX遺伝子変異はWilms腫瘍の予後因子である2015
- Author(s)
  春田雅之、新井康仁、大喜多肇、大植孝治、野崎美和子、越永従道、福澤正洋、上條岳彦、金子安比古
- Organizer
  第74回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26461600
[Presentation] Relationships between genetic and chromosomal alterations and outcomes in Japanese Wilms tumor patients2015
- Author(s)
  春田雅之, 大島淳二郎, 新井康仁, 大喜多肇, 大植孝治, 田中祐吉, 野崎美和子, 瀧本哲也, 越永従道, 福澤正洋, 上條岳彦, 金子安比古
- Organizer
  第57回日本小児血液･がん学会学術集会
- Place of Presentation
  甲府富士屋ホテル
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-26461600
[Presentation] Polycomb member proteins are new target of anti-neuroblastoma therapy2015
- Author(s)
  力石浩志、秋田直洋、春田雅之、大平美紀、竹信尚典、古関明彦、上條岳彦
- Organizer
  第57回日本小児血液･がん学会学術集会
- Place of Presentation
  甲府富士屋ホテル
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-26461600
[Presentation] ポリコーム群タンパク質L3MBTL2はBMI1と協調的に腫瘍細胞死を抑制する2015
- Author(s)
  力石浩志、秋田直洋、春田雅之、大平美紀、竹信尚典、古関明彦、上條岳彦
- Organizer
  第74回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26461600
[Presentation] 神経芽腫のがん幹細胞性を制御する経路の探索2015
- Author(s)
  竹信尚典、大平美紀、力石浩志、秋田直洋、山口 (末永) 陽子、春田雅之、古関明彦、上條岳彦
- Organizer
  第74回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26461600
[Presentation] WTX 遺伝子変異は腎芽腫の予後予測因子である2012
- Author(s)
  春田雅之, 他
- Organizer
  第54回日本小児血液・がん学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24791099
[Presentation] WTX mutation is a new prognostic factor for Wilms tumor2012
- Author(s)
  Haruta M, et. Al
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24791099
[Presentation] WTX mutation is a new prognostic factor for Wilms tumor.2012
- Author(s)
  Haruta M, et. al.
- Organizer
  第７１回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24791099
[Presentation] WTX遺伝子変異は腎芽腫の予後予測因子である2012
- Author(s)
  春田雅之　他
- Organizer
  第５３回日本小児血液･がん学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24791099
[Presentation] がん抑制遺伝子RASSF1Aのプロモーターメチル化はWilms腫瘍の予後不良因子である2011
- Author(s)
  大島淳二,郎春田雅之, 他
- Organizer
  第53回日本小児血液・がん学会学術集会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-21791021
[Presentation] The different incidence rate of Wilms in races profoundly contributes to IGF2LOI, but not abnormality of WT1, WTX and CTNNB1.2010
- Author(s)
  Haruta M, et.al.
- Organizer
  AACR 101^<st> Annual Meeting
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-21791021
[Presentation] HER2 genomic copy mumber predicts response to trastuzumab-combined chemotherapy better than HER2 immunohistochemistry.2010
- Author(s)
  Higuchi T, Kasai F, Haruta M, et.al.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21791021
[Presentation] SNP array patterns in Wilms tumors with the possibility of abnormalities of unknown genes responsible for tomorigenesis2010
- Author(s)
  Haruta M, et. al
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21791021
[Presentation] The different incidence rate of Wilms in races profoundly contributes toIGF2 LOI, but not abnormality of WT1, WTX and CTNNB12010
- Author(s)
  Haruta M, et. Al
- Organizer
  AACR 101^<st> Annual Meeting
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-21791021
[Presentation] TP53 germeline mutations may induce oncogene amplification in tumors developing in patients with Li-Fraumeni syndrome.2010
- Author(s)
  Kaneko Y, Arai Y, Kasai F, Haruta M, et.al.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21791021
[Presentation] SNPアレイ解析により検出された肝芽腫の4q欠失は予後不良因子である2009
- Author(s)
  金子安比古、新井康仁、本多昌平、春田雅之, 他
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21791021
[Presentation] Wilms腫瘍の7p21ホモ欠失領域から同定された候補腫瘍抑制遺伝子MEOX2とSOTDC12009
- Author(s)
  大島淳二郎、春田雅之, 他
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21791021
[Presentation] Loss of Heterozygosity Analysis in Wilms Tumor2009
- Author(s)
  Padilla R, Haruta M, et. al
- Organizer
  ASHG 59th Annual Meeting
- Place of Presentation
  Honolulu
- Data Source
  KAKENHI-PROJECT-21791021
[Presentation] ウィルムス腫瘍で初めて同定されたAPC遺伝子変異2009
- Author(s)
  春田雅之, 他
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21791021
[Presentation] Wilms腫瘍の7p21ホモ欠失領域から同定された候補腫瘍抑制遺伝子MEOX2とSOTDC12009
- Author(s)
  大島淳二郎春田雅之, 他
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21791021
[Presentation] ウィルムス腫瘍で初めて同定されたAPC遺伝子変異2009
- Author(s)
  春田雅之, 他
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21791021
[Presentation] 乳児と小児2倍体神経芽腫の特徴-中心体の増幅と異数性細胞の混在-2008
- Author(s)
  笠井文生、福士大輔、渡辺直樹、春田雅之、金子安比古
- Organizer
  第67回日本癌学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390475
[Presentation] Centrosome amplification is correlated with ploidy instability in infant neuroblastoma (NB) tumors, but not with MYCN amplification in infant and childhood NB tumors or cell line2008
- Author(s)
  Kaneko Y, Fukushi D, Watanabe N, Kasai F, Haruta M, Kikuchi A, Kikuta A, Tsunematsu Y
- Organizer
  Advances in Neuroblastoma Research
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-18390475
[Presentation] 神経芽腫のploidy異常の発生に3極分極が関与するのか?2007
- Author(s)
  福士大輔、渡辺直樹、春田雅之、金子安比古
- Organizer
  第66回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390475
[Presentation] Loss of imprinting (LOI) of IGF2was found in a substantial number of Wilms tumors in Japanese children.2007
- Author(s)
  Haruta M, et. al.
- Organizer
  American Association for Cancer Research Annual Meeting 2007
- Place of Presentation
  Los Angels Convention Center
- Year and Date
  2007-04-15
- Data Source
  KAKENHI-PROJECT-18790745
[Presentation] 神経芽腫のploidy異常の発生に中心体異常は関与するのか?2006
- Author(s)
  福士大輔、渡辺直樹、春田雅之、金子安比古
- Organizer
  第22回日本小児がん学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18390475
[Presentation] マススクリ-ニングで発見された神経芽腫におけるアポトーシス関連遺伝子のメチル化異常2006
- Author(s)
  春田雅之、大平美紀、中川原章、金子安比古
- Organizer
  第22回日本小児がん学会.
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18390475
[Presentation] RASSF1A遺伝子DNAメチル化は神経芽腫の患者年齢とploidyにより異なる生物学的役割をもつ
- Author(s)
  春田雅之、上條岳彦、中川原章、金子安比古
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26461600
[Presentation] WT1 遺伝子異常タイプとその親由来が遺伝性 Wilms 腫瘍の浸透率に影響する
- Author(s)
  金子安比古、大喜多肇、春田雅之、新井康仁、大植孝治、越永従道、福澤正洋
- Organizer
  第59回日本人類遺伝学会
- Place of Presentation
  東京
- Year and Date
  2014-11-19 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26461600
[Presentation] DNAメチル化解析による肝芽腫の新規予後予測マーカーの確立
- Author(s)
  本多昌平、湊雅嗣、鈴木拓、春田雅之、金子安比古、檜山英三、武冨紹信
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26461600
[Presentation] Parental Inheritance and WT1 Abnormality Types May Affect the Penetrance Rate of Hereditary Wilms Tumor.
- Author(s)
  Y. Kaneko, H. Okita, M. Haruta, Y. Arai, T. Oue, T. Koshinaga, M. Fukuzawa
- Organizer
  The 63rd Annual Meeting of the American Society of Human Genetics
- Place of Presentation
  San Diego
- Year and Date
  2014-10-18 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-26461600
[Presentation] BRCA1関連ゲノム異常は予後良好トリプルネガティブ乳癌と、BRCA2関連ゲノム異常は予後不良ER陽性乳癌と相関する
- Author(s)
  金子安比古、高田護、春田雅之、戸塚勝理、武井寛幸、永井成勲、井上賢一、黒住昌史、宮崎勝、佐藤亜以子、佐藤悠祐、小川誠司
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26461600
[Presentation] RASSF1A遺伝子DNAメチル化は神経芽腫の患者年齢とploidyにより異なる生物学的役割をもつ
- Author(s)
  春田雅之, 上條岳彦, 中川原章, 金子安比古
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24390269

1. KANEKO Yasuhiko (50373387)

# of Collaborated Projects: 3 results

# of Collaborated Products: 40 results
2. KASAI Fumio (60393055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. FUKUSHI Daisuke (90397159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. KAMIJO Takehiko (90262708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. KOSHINAGA Tsugumichi (70205376)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. 田尻達郎 (80304806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 吉田英生 (60210712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 竹信尚典 (60392247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 野崎美和子 (10175523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 瀧本哲也 (40393178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. 陳基明 (50277422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. 大植孝治 (50314315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
13. 大喜多肇 (50317260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
14. 井上永介 (50528338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 谷ヶ崎博 (90378141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 安藤清宏 (10455389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 川村眞智子 (80450592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. 小林泰文 (50455375)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KANEKO Michio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. FUKUZAWA Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. Yamada Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. HONDA Shohei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 中川原章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 滝智彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
25. 桧山英三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 田中祐吉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 田中水緒

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HARUTA Masayuki 春田 雅之

Research Projects

Research Products

Co-Researchers

小児腎腫瘍（腎芽腫）における11p13-14の新規原因遺伝子同定と機能解析Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

思春期若年成人白血病のクロモスリプシスによる悪性化機構解明とゲノム医療への応用

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

A novel strategy for pediatric renal tumors using biomarkers as indicators

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of drug-resistant mechanism in nephroblastoma with WTX abnormalityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of cancer stem cell-targeted therapy by study of tumor sphere formation mechanism using comprehensive and genetic approach

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of prognostic factor(s) by analysis of genetic abnormality and elucidation of the mechanism of drug resistance in nephroblastomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of genes involved inβ-catenin degradation in nephroblastomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism of polyploidy and aneuploidy formation in neuroblastoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ウイルムス腫瘍における細胞周期制御遺伝子のエピジェネティック異常Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

[Journal Article] Frequent breakpoints of focal deletion and uniparental disomy in 22q11.1 or 11.2 segmental duplication region reveal distinct tumorigenesis in rhabdoid tumor of the kidney2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Blastemal predominant type Wilms tumor in Japan: Japan Children's Cancer Group.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Paternally inherited WT1 mutation plus uniparental disomy of 11p may be an essential mechanism for development of WT1-mutated familial Wilms tumor.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combined Genetic and Chromosomal Characterization of Wilms Tumors Identifies Chromosome 12 Gain as a Potential New Marker Predicting a Favorable Outcome,2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Outcome of renal tumors registered in Japan Wilms Tumor Study-2 (JWiTS-2): A report from the Japan Children's Cancer Group (JCCG)2018

Author(s)

HARUTA Masayuki 春田雅之