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Kubota Reiji  久保田 領志

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KUBOTA Reiji  久保田 領志

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Researcher Number 80392299
Other IDs
Affiliation (Current) 2025: 国立医薬品食品衛生研究所, 生活衛生化学部, 室長
Affiliation (based on the past Project Information) *help 2016 – 2018: 国立医薬品食品衛生研究所, 生活衛生化学部, 主任研究官
2011 – 2013: 国立医薬品食品衛生研究所, 生活衛生化学部, 主任研究官
2007 – 2008: National Institute of Health Sciences, 環境衛生化学部, 主任研究官
2006: 国立医薬品食品衛生研究所, 環境衛生化学部, 研究員
Review Section/Research Field
Principal Investigator
Risk sciences of radiation/Chemicals / Environmental risk control and evaluation
Keywords
Principal Investigator
フラーレン / 汚染物質 / 水環境 / パッシブ法 / モニタリング / LC-MS/MS / 水酸化物 / LC-MS/MS / 一斉分析法 / 酸化物 … More / 肝ミクロゾーム / 細胞毒性 / in vitro / LC/MS/MS / 代謝物 / 投与 / 腹腔内投与 / マウス / 尾静脈投与 / ラット / in vivo / 高感度分析法 / MS / LC-MS / 健康影響評価 / ナノマテリアル / 微量化学物質汚染評価 Less
  • Research Projects

    (3 results)
  • Research Products

    (15 results)
  •  Establishment and application of time weighted average sampling method for continuous monitoring and recording of pollutants in water environmentPrincipal Investigator

    • Principal Investigator
      Kubota Reiji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental risk control and evaluation
    • Research Institution
      National Institute of Health Sciences
  •  A study on metabolic pathway of fullerene C60 in vivo.Principal Investigator

    • Principal Investigator
      KUBOTA Reiji
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      National Institute of Health Sciences
  •  Development of a sensitive method for determination of fullerenes in biological samples and health risk assessmentPrincipal Investigator

    • Principal Investigator
      KUBOTA Reiji
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      National Institute of Health Sciences

All 2012 2011 2010 2009 2008 2006

All Journal Article Presentation

  • [Journal Article] Sub-acute oral toxicity study with fullerene C60 in rats2012

    • Author(s)
      Takahashi, M., Kato, H., Doi, Y., Hagiwara, A., Hirata-Koizumi, M., Ono, A., Kubota, R., Nishimura, T., Hirose, A.
    • Journal Title

      The Journal of Toxicological Sciences

      Volume: 37, 2 April Pages: 353-361

    • NAID

      10030126828

    • Data Source
      KAKENHI-PROJECT-23710083
  • [Journal Article] Time-dependent variation in the biodistribution of C60 in rats determined by liquid chromatography-tandem mass spectrometry2011

    • Author(s)
      Kubota, R., Tahara, M., Shimizu, K., Sugimoto, N., Hirose, A., Nishimura T.
    • Journal Title

      Toxicology Letters

      Volume: 206 Pages: 172-177

    • Data Source
      KAKENHI-PROJECT-23710083
  • [Presentation] Time-dependent biodistribution of C60 in rat after tail-vein administration2011

    • Author(s)
      Kubota, R., Tahara, M., Shimizu, K., Kobayashi, N., Sugimoto, N., Hirose, A., Nishimura T.
    • Organizer
      47th Congress of the European Societies of Toxicology, abstracts.
    • Place of Presentation
      Paris, France(2342)
    • Data Source
      KAKENHI-PROJECT-23710083
  • [Presentation] Bio-distribution of fullerenes intravenous administration in rat2011

    • Author(s)
      Nishimura, T., Kubota, R., Tahara, M., Shimizu, K., Obama, T., Sugimoto, N., Hirose, A.
    • Organizer
      50th Anniversary Annual Meeting & ToxExpo, abstracts
    • Place of Presentation
      SOT, Washington, D.C., USA
    • Data Source
      KAKENHI-PROJECT-23710083
  • [Presentation] Bio-distribution of C60 fullerene injected into the rat tail vein2011

    • Author(s)
      Nishimura, T., Kubota, R., Tahara, M., Shimizu, K., Obama, T., Hirose, A., Sugimoto, N.
    • Organizer
      5th International Symposium on Nanotechnology, Occupational and Environmental Health (NanOEH)
    • Place of Presentation
      Boston, USA(abstracts)
    • Data Source
      KAKENHI-PROJECT-23710083
  • [Presentation] Bio-distribution of fullerenes intravenous administration2010

    • Author(s)
      Nishimura, T., Kubota, R., Tahara, M., Shimizu, K., Obama, T., Sugimoto, N., Hirose, A., Ikarashi, Y.
    • Organizer
      2010 Annual Meeting of the Korea Society of Environmental Health and Toxicology, abstracts
    • Place of Presentation
      Suwon, Korea
    • Data Source
      KAKENHI-PROJECT-23710083
  • [Presentation] Tissue distribution of fullerene after injected into rat tail vein to mimic the absorption from the digestive tract2010

    • Author(s)
      Nishimura, T., Kubota, R., Shimizu, K., Tahara, M., Obama, T., Sugimoto, N., Kanno, J., Hirose, A.
    • Organizer
      XII International Congress of Toxicology, abstracts. P303-024
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-23710083
  • [Presentation] LC-MS/MSによるC60フラーレンのラットへの経口、尾静脈投与による体内分布2009

    • Author(s)
      久保田領志、田原麻衣子、清水久美子、杉本直樹、西村哲治
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18710059
  • [Presentation] LC-MS/MSによるC60フラーレンへの経口、尾静脈投与による体内分布2009

    • Author(s)
      久保田領志, 田原麻衣子, 清水久美子, 杉本直樹, 西村哲治
    • Organizer
      日本薬理学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-18710059
  • [Presentation] Tissue distribution of fullerene C60 in rat after oral and tail-vein administration by LC-MS/MS2008

    • Author(s)
      Kubota, R., Tahara, M., Shimizu, K.., Hirose A., Shimizu, K., Oku, N., and Nishimura, T
    • Organizer
      The 45th Congress of the European Societies of Toxicology
    • Place of Presentation
      Rhodes, Greece
    • Data Source
      KAKENHI-PROJECT-18710059
  • [Presentation] Quantitative determination of C60 fullerene by LC-MS/MS and its tissue distribution following oral administration2008

    • Author(s)
      Kubota, R., Tahara, M., Shimizu, K.., Tokunaga, H., Hirose A., Ema, M., and Nishimura, T
    • Organizer
      47th of the Society of Toxicology Annual Meeting
    • Place of Presentation
      Seattle, USA
    • Data Source
      KAKENHI-PROJECT-18710059
  • [Presentation] Tissue distribution of fullerene C60 in rat after oral and tail-vein administration by LC-MS/MS2008

    • Author(s)
      Kubota, R., Tahara, M., Shimizu, K., Hirose A., Shimizu, K., Oku, N., and Nishimura, T.
    • Organizer
      The 45^<th> Congress of the European Societies of Toxicology
    • Place of Presentation
      Rhodes, Greece
    • Year and Date
      2008-10-07
    • Data Source
      KAKENHI-PROJECT-18710059
  • [Presentation] Quantitative determination of C60 fullerene by LC-MS/MS and its tissue distribution following oral administration.2008

    • Author(s)
      Kubota, R., Tahara, M., Shimizu, K., Tokunaga, H., Hirose A., Ema, M., and Nishimura, T.
    • Organizer
      47th of the Society of Toxicology Annual Meeting
    • Place of Presentation
      Seattle, USA
    • Data Source
      KAKENHI-PROJECT-18710059
  • [Presentation] Tissue distribution of C60 fullerene in mice after intraperitoneal administration by liquid chromatography-tandem massspectrometry2006

    • Author(s)
      Kubota, R., Tahara, M., Shimizu, K.., Tokunaga, H., Hirose A., and Nishimura, T
    • Organizer
      27th Annual Meeting of American College of Toxicology
    • Place of Presentation
      Indian Wells, USA
    • Data Source
      KAKENHI-PROJECT-18710059
  • [Presentation] Tissue distribution of C60 fullerene in micea after intraperitoneal administration by liquid chromatography-tandem mass spectrometry.2006

    • Author(s)
      Kubota, R., Tahara, M., Shimizu, K., Tokunaga, H., Hirose A., and Nishimura, T.
    • Organizer
      27th Annual Meeting of American College of Toxicology
    • Place of Presentation
      Indian Wells, USA
    • Data Source
      KAKENHI-PROJECT-18710059

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