NAKAMURA Akiko 中村明子

Researcher Number	80397413
Affiliation (based on the past Project Information) *help	2006: Hamamatsu University School of Medicine, First Department of Medicine, 医学附属病院, 医員 2005: 浜松医科大学, 医学部附属病院, 医員
Review Section/Research Field	Except Principal Investigator Applied pharmacology
Keywords	Except Principal Investigator 23S rRNA / CYP2C19 / eradication / amoxicillin / clarithromycin / lansoprazole / tailored Medicine / Helicobacter pylori / 遺伝子多型 / テーラーメイド … More / H.pylori / 除菌療法 / アモキシシリン / クラリスロマイシン / ランソプラゾール / テーラーメイド治療 / 23S RNA / ヘリコバクター・ピロリ / CYP2Cl9 Less

Pharmacogenomics-based tailored strategy for eradication of H. pylori
- Principal Investigator
  
  FURUTA Takahisa
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Hamamatsu University School of Medicine

All 2007 2006 2005 Other

All Journal Article Book

[Book] Recent Advance in Gastrointestinal Carcinogenesis, polymorphisms associated with gastric cancer risks2006
- Author(s)
  Furuta T, Shirai N, Sugimoto M, Nakamura A, Sugimura H, Hishida A
- Publisher
  TRANSWORLD RESEARCH NETWORK
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Book] Recent Advance in Gastrointestinal Carcinogenesis
- Author(s)
  Furuta T, Shirai N, Sugimoto M, Nakamura A, Sugimura H, Hishida A.
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Different effects of polymorphisms of tumor necrosis factor-alpha and interleukin-1 beta on development of peptic ulcer and gastric cancer2007
- Author(s)
  Sugimoto M, Furuta T, Shirai N, Nakamura A, Xiao F, Kajimura M, Sugimura H, Hishida A
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 51-59
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Different effects of polymorphisms of tumor necrosis factor-alpha an interleukin-1 beta on development of peptic ulcer and gastric cancer2007
- Author(s)
  Sugimoto M, Furuta T, Shirai N, Nakamura A, Xiao I, Kajimura M, Sugimura H, Hishida A.
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 51-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Hydroxylation of lansopraozle in poor metabolizers of CYP2C19.2006
- Author(s)
  Furuta T, Shirai N, Sugimoto M, Nakamura A, Hishida A.
- Journal Title
  
  British Journal of Clin Pharmacol 61
  
  Pages: 361-361
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Helicobacter pylori eradication and metachronous gastric cancer after endoscopic mucosal resection of early gastric cancer.2006
- Author(s)
  Nakagawa S, Asaka M, Kato M, Nakamura T, Kato C, Fujioka T, Tatsuta M, Keida K, Terao S, Takahashi S, Uemura N, Kato T, Aoyama N, Saito D, Suzuki M, Imamura A, Sato K, Miwa H, Nomura H, Kaise M, Oohara S, Kawai T, Urabe K, Sakaki N, Ito S, Noda Y, Yanaka A, Kusugami K, Goto H, Furuta T, Fujino M, Kinjyou F, Ookusa T
- Journal Title
  
  Aliment Pharmacol Ther. 2006 Suppl 4
  
  Pages: 214-218
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Helicobacter pylori eradication and metachronous gastric cancer after endoscopic mucosal resection of earl gastric cancer.2006
- Author(s)
  Nakagawa S, Asaka M, Kato M, Nakamura T, Kato C, Fujioka T, Tatsuta M, Keida K, Terao S, Takahashi S, Uemura N, Kato T, Aoyama N, Saito D, Suzuki M, Imamura A, Sato K, Miwa H, Nomura H, Kaise M, Oohara S, Kawai T, Urabe K, Sakaki N, Ito S, Noda Y, Yanaka A, Kusugami K, Goto H, Furuta T, Fujino M, Kinjyou F, Ookusa T.
- Journal Title
  
  Aliment Pharmacol Ther Suppl 4
  
  Pages: 214-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Hydroxylation of lansopraozle in poor metabolizers of CYP2C19.2006
- Author(s)
  Furuta T, Shirai N, Sugimoto M, Nakamura A, Hishida A
- Journal Title
  
  British Journal of Clin Pharmacol 61
  
  Pages: 361-361
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] 二次除菌療法の検討一次除菌無効例における薬物感受性、薬物代謝・動態とそれに基づく投与法の検討-CAM感受性検査、CYP2Cl9のSNP検査-2005
- Author(s)
  古田隆久, 白井直人, 杉本光繁, 中村明子
- Journal Title
  
  日本臨床 63 Supple 11
  
  Pages: 426-433
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Influence of CYP 2C19 polymorphism and H. pylori genotype determined from gastric tissue samples on response to triple therapy for H. pylori infection.2005
- Author(s)
  Furuta T, Sagehashi Y, Shirai N, Sugimoto M, Nakamura A, Kodaira M, Kenmotsu K, Nagano M, Egashira T, Ueda K, Yoneyama M, Ohashi K, Ishizaki T, Hishida A.
- Journal Title
  
  Clin Gastroenterol Hepatol 3
  
  Pages: 564-73
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] 肝薬物代謝酵素の関与におけるPPI・H2RAの比較.2005
- Author(s)
  古田隆久, 白井直人, 杉本光繁, 中村明子
- Journal Title
  
  臨床消化器内科 20
  
  Pages: 1137-1147
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] PPIの効果と遺伝子多型.2005
- Author(s)
  古田隆久, 白井直人, 杉本光繁, 中村明子
- Journal Title
  
  治療学 2005,39(5):532-4. 39
  
  Pages: 532-534
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Poor metabolizer genotype status of CYP2C19 is a risk factor for developing gastric cancer in Japanese patients with Helicobacter pylori infection2005
- Author(s)
  Sugimoto M, Furuta T, Shirai N, Nakamura A, Kajimura M, Sugimura H, Hishida A, Ishizaki
- Journal Title
  
  Aliment Pharmacol Ther 22
  
  Pages: 1033-1040
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Effect of concomitant dosing of famotidine with lansoprazole on gastric acid secretion in relation to CYP2C19 genotype status2005
- Author(s)
  Furuta T, Shirai N, Sugimoto M, Nakamura A, Okudaira K, Kajimura M. Hishida A
- Journal Title
  
  Aliment Pharmacol Ther 22
  
  Pages: 67-74
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Influence of CYP2C19 Pharmacogenetic Polymorphism on Proton Pump Inhibitor-based Therapies.2005
- Author(s)
  Furuta T, Shirai N, Sugimoto M, Nakamura A, Hishida A, Ishizaki T.
- Journal Title
  
  Drug Metab Pharmacokinet. 20
  
  Pages: 153-67
- NAID
  130004462957
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Influence of CYP 2C19 polymorphism and H. pylori genotype determined from gastric tissue samples on response to triple therapy for H. pylori infection2005
- Author(s)
  Furuta T, Sagehashi Y, Shirai N, Sugimoto M, Nakamura A, Kodaira M, et al.
- Journal Title
  
  Clin Gastroenterol Hepatol 3
  
  Pages: 564-573
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] CYP2C19遺伝子多型とプロトンポンプ阻害薬動態の個体差に基づく薬物投与設計.2005
- Author(s)
  古田隆久, 白井直人, 杉本光繁, 中村明子, 菱田明, 石崎高志
- Journal Title
  
  DMPKレクチャーノート 20
  
  Pages: 8-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Effect of concomitant dosing of famotidine with lansoprazole on gastric acid secretion in relation to CYP2C19 genotype status2005
- Author(s)
  Furuta T, Shirai N, Sugimoto M, Nakamura A, Okudaira K, Kajimura M, Hishida A
- Journal Title
  
  Aliment Pharmacol Ther 22
  
  Pages: 67-74
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] プロトンポンプ阻害剤ラベプラゾール2005
- Author(s)
  杉本光繁, 古田隆久, 白井直人, 中村明子
- Journal Title
  
  日本臨床 63 Supple 11
  
  Pages: 350-353
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Effect of concomitant dosing of famotidine with lansoprazole on gastric acid secretion in relation to CYP2C19 genotype status.2005
- Author(s)
  Furuta T, Shirai N, Sugimoto M, Nakamura A, Okudaira K, Kajimura M, Hishida A.
- Journal Title
  
  Aliment Pharmacol Ther 22
  
  Pages: 67-74
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Influence of CYP2C19 Pharmacogenetic Polymorphism on Proton Pump Inhibitor-based Therapies.2005
- Author(s)
  Furuta T, Shirai N, Sugimoto M, Nakamura A, Hishida A, Ishizaki T
- Journal Title
  
  Drug Metab Pharmacokinet 20
  
  Pages: 153-167
- NAID
  130004462957
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] 二次除菌治療の検討二次除菌レジメの検討高用量2剤併用療法(PPI+AMPC分轄投与)2005
- Author(s)
  白井直人, 古田隆久, 杉本光繁, 中村明子
- Journal Title
  
  日本臨床 63 Supple 11
  
  Pages: 438-441
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Poor metabolize genotype status of CYP2C19 is a risk factor for developing gastric cancer in Japanese patients with Helicobacter pylori infection2005
- Author(s)
  Sugimoto M, Furuta T, Shirai N, Nakamura A, Kajimura M, Sugimura H, Hishida A,, Ishizaki.
- Journal Title
  
  Aliment Pharmacol Ther 22
  
  Pages: 1033-40
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Influence of CYP 2C19 polymorphism and H.pylori genotype determined from gastric tissue samples on response to triple therapy for H.pylori infection2005
- Author(s)
  Furuta T, Sagehashi Y, Shirai N, Sugimoto M, Nakamura A, Kodaira M, et al.
- Journal Title
  
  Clin Gastroenterol Hepatol 3
  
  Pages: 564-573
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] 消化器疾患用薬のファーマコジェノミクスと薬力学薬-効・副作用・相互作用-.2005
- Author(s)
  古田隆久, 白井直人, 杉本光繁, 中村明子, 菱田明
- Journal Title
  
  最新医学 60
  
  Pages: 1879-1890
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] 二次除菌療法の検討一次除菌無効例における薬物感受性、薬物代謝・動態とそれに基づく投与法の検討-CAM感受性検査、CYP2C19のSNP検査-2005
- Author(s)
  古田隆久, 白井直人, 杉本光繁, 中村明子
- Journal Title
  
  日本臨床 63・Supple 11
  
  Pages: 426-433
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Determination of Mutations of 23S rRNA Gene of H. pylori by Allele Specific Primer-PCR method.
- Author(s)
  Nakamura A, Furuta T, Shirai N, Sugimoto M, Kajimuram M, Soya Y, Hishida A
- Journal Title
  
  J Gastroenterol Hepatol (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Modified allele specific primer-PCR method for analyses of susceptibility of H. pylori strains to clarithromycin.
- Author(s)
  Furuta T, Soya Y, Sugimoto M, Shirai N, Nakamura A, Kodaira, Nishino M, Okuda M, Okimoto T, Murakami K, Fujioka T, Akira Hishida A.
- Journal Title
  
  J Gastroenterol Hepatol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Effects of Interleukin-10 gene polymorphism on the development of gastric cancer and peptic ulcer in Japanese.
- Author(s)
  Sugimoto M, Furuta T, Shirai N, Nakamura A, Kajimura M, Haruhiko Sugimura H, Hishida A
- Journal Title
  
  J Gastroenterol Hepatol (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Effects of Interleukin-10 gene polymorphism on the development of gastric cancer and peptic ulcer in Japanese.
- Author(s)
  Sugimoto M, Furuta T, Shirai N, Nakamura A, Kajimura M, Haruhiko Sugimura H, Hishida A.
- Journal Title
  
  J Gastroenterol Hepatol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Modified allele specific primer-PCR method for analyses of susceptibility of H. pylori strains to clarithromycin
- Author(s)
  Furuta T, Soya Y, Sugimoto M, Shirai N, Nakamura A, Kodaira, Nishino M, Okuda M, Okimoto T, Murakami K, Fujioka T, Akira Hishida A.
- Journal Title
  
  J Gastroenterol Hepatol (In press)
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Modified allele specific primer-PCR method for analyses of susceptibility of H. pylori strains to clarithromycin
- Author(s)
  Furuta T, Soya Y, Sugimoto M, Shirai N, Nakamura A, Kodaira, Nishino M, Okuda M, Okimoto T, Murakami K, Fujioka T, Akira Hishida A
- Journal Title
  
  J Gastroenterol Hepatol (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590470
[Journal Article] Determination of Mutations of 23S rRNA Gene of H. pylori by Allele Specific Primer-PCR method
- Author(s)
  Nakamura A, Furuta T, Shirai N, Sugimoto M, Kajimuram M, Soya Y, Hishida A.
- Journal Title
  
  J Gastroenterol Hepatol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590470

1. FURUTA Takahisa (10303546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 33 results
2. SHIRAI Naohito (90362194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 31 results
3. SUGIMOTO Mistustuge (80397398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 31 results

NAKAMURA Akiko 中村 明子

Research Projects

Research Products

Co-Researchers

Pharmacogenomics-based tailored strategy for eradication of H. pylori

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Recent Advance in Gastrointestinal Carcinogenesis, polymorphisms associated with gastric cancer risks2006

Author(s)

Publisher

Description

Data Source

[Book] Recent Advance in Gastrointestinal Carcinogenesis

Author(s)

Data Source

[Journal Article] Different effects of polymorphisms of tumor necrosis factor-alpha and interleukin-1 beta on development of peptic ulcer and gastric cancer2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Different effects of polymorphisms of tumor necrosis factor-alpha an interleukin-1 beta on development of peptic ulcer and gastric cancer2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Hydroxylation of lansopraozle in poor metabolizers of CYP2C19.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Helicobacter pylori eradication and metachronous gastric cancer after endoscopic mucosal resection of early gastric cancer.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Helicobacter pylori eradication and metachronous gastric cancer after endoscopic mucosal resection of earl gastric cancer.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Hydroxylation of lansopraozle in poor metabolizers of CYP2C19.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] 二次除菌療法の検討 一次除菌無効例における薬物感受性、薬物代謝・動態とそれに基づく投与法の検討-CAM感受性検査、CYP2Cl9のSNP検査-2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Influence of CYP 2C19 polymorphism and H. pylori genotype determined from gastric tissue samples on response to triple therapy for H. pylori infection.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] 肝薬物代謝酵素の関与におけるPPI・H2RAの比較.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] PPIの効果と遺伝子多型.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Poor metabolizer genotype status of CYP2C19 is a risk factor for developing gastric cancer in Japanese patients with Helicobacter pylori infection2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Effect of concomitant dosing of famotidine with lansoprazole on gastric acid secretion in relation to CYP2C19 genotype status2005

Author(s)

Journal Title

Data Source

[Journal Article] Influence of CYP2C19 Pharmacogenetic Polymorphism on Proton Pump Inhibitor-based Therapies.2005

Author(s)

Journal Title

NAKAMURA Akiko 中村明子

[Journal Article] 二次除菌療法の検討一次除菌無効例における薬物感受性、薬物代謝・動態とそれに基づく投与法の検討-CAM感受性検査、CYP2Cl9のSNP検査-2005

[Journal Article] プロトンポンプ阻害剤ラベプラゾール2005

[Journal Article] 二次除菌治療の検討二次除菌レジメの検討高用量2剤併用療法(PPI+AMPC分轄投与)2005

[Journal Article] 二次除菌療法の検討一次除菌無効例における薬物感受性、薬物代謝・動態とそれに基づく投与法の検討-CAM感受性検査、CYP2C19のSNP検査-2005