Hayashi Aki 林亜紀

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HAYASHI Aki 林亜紀

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Researcher Number	80399534
Other IDs
Affiliation (Current)	2025: 基礎生物学研究所, クロマチン制御研究部門, 特任助教
Affiliation (based on the past Project Information) *help	2017: 関西学院大学, 理工学部, 助教 2013: 独立行政法人理化学研究所, その他部局等, 研究員 2010 – 2013: 独立行政法人理化学研究所, クロマチン動態研究チーム, 研究員
Review Section/Research Field	Principal Investigator Genetics/Chromosome dynamics / Molecular biology Except Principal Investigator Applied molecular and cellular biology / Genetics/Genome dynamics
Keywords	Principal Investigator HP1 / ヒストン修飾 / RNAi機構 / ヘテロクロマチン Except Principal Investigator 分裂酵母 / ゲノム / SUMO翻訳後修飾 / Rif1 / SUMO / タンパク質翻訳後修飾 … More / テロメア / 染色体 / ユビキチン化 / RNAi / RNA干渉 / ヘテロクロマチン / 発現制御 / 遺伝子 Less

The search for the novel safeguard system to maintain the telomere length
- Principal Investigator
  
  Tanaka Katsunori
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Kwansei Gakuin University
RNAi機構が介するヘテロクロマチン形成を制御する細胞内事象メカニズムの解析Principal Investigator
- Principal Investigator
  
  林亜紀
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  The Institute of Physical and Chemical Research
The molecular mechanisms of heterochromatin establishment and maintenance
- Principal Investigator
  
  NAKAYAMA Jun-ichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  Nagoya City University
  The Institute of Physical and Chemical Research
Analysis of the mechanism of histone methylation by using genetic approachesPrincipal Investigator
- Principal Investigator
  
  HAYASHI Aki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  The Institute of Physical and Chemical Research

All 2012 2011

All Journal Article Presentation

[Journal Article] A novel RNAi protein, Dsh1, assembles RNAi machinery on chromatin to amplify heterochromatic siRNA2012
- Author(s)
  Kawakami K, Hayashi A, Nakayama J, Murakami Y.
- Journal Title
  
  Genes Dev.
  
  Volume: 26 Pages: 1811-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570176
[Journal Article] Two different RFC proteins, Ctf18 and RFC1 separately control PCNA-CRL4Cdt2-mediated Cdt1 proteolysis during S phase and following UV-irradiation2012
- Author(s)
  Shiomi Y, Ishii T, Hayashi A, Shinmyozu K, Nakayama J, Sugasawa K, & Nishitani H
- Journal Title
  
  Mol Cell Biol
  
  Volume: 32 Issue: 12 Pages: 2279-88
- DOI
  10.1128/mcb.06506-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370004, KAKENHI-PROJECT-24241019, KAKENHI-ORGANIZER-23114001, KAKENHI-PLANNED-23114005, KAKENHI-PLANNED-23116008, KAKENHI-PUBLICLY-23131512
[Journal Article] Intrinsic nucleic acid-binding activity of Chp1 chromodomain is required for heterochromatin assembly2012
- Author(s)
  3.Ishida M, Shimojo H, Hayashi A, Kawaguchi R, Ohtani Y, Uegaki K, Nishimura Y, Nakayama J.
- Journal Title
  
  Mol Cell.
  
  Volume: 47 Pages: 1-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570176
[Journal Article] Heterochromatin protein 1 homologue Swi6 acts in concert with Ers1 to regulate RNAi-directed heterochromatin assembly2012
- Author(s)
  Hayashi, A., Ishida, M., Kawaguchi, R., Urano, T., Murakami, Y., Nakayama, J-I.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: (印刷中) Issue: 16 Pages: 6159-64
- DOI
  10.1073/pnas.1116972109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247001, KAKENHI-PUBLICLY-22019001, KAKENHI-PUBLICLY-23114701, KAKENHI-PROJECT-23370004, KAKENHI-ORGANIZER-23114001, KAKENHI-PLANNED-23114005
[Journal Article] Heterochromatin protein 1 homologue Swi6 acts in concert with Ers1 to regulate RNAi-directed heterochromatin assembly2012
- Author(s)
  Hayashi A, Ishida M, Kawaguchi R, Urano T, Murakami Y, Nakayama J.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 109 Pages: 6159-6164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570176
[Journal Article] Intrinsic Nucleic Acid-Binding activity of Chp1 Chromodomain Is Required for Heterochromatic Gene Silencing2012
- Author(s)
  Ishida M, Shimojo H, Hayashi A, Kawaguchi R, Ohtani Y, Uegaki K, Nishimura Y, Nakayama J
- Journal Title
  
  Mol Cell
  
  Volume: 47 Issue: 2 Pages: 228-241
- DOI
  10.1016/j.molcel.2012.05.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20227009, KAKENHI-PLANNED-21113003, KAKENHI-PROJECT-22570128, KAKENHI-PROJECT-23370004, KAKENHI-ORGANIZER-23114001, KAKENHI-PLANNED-23114005
[Journal Article] A novel RNAi protein, Dsh1, assembles RNAi machinery on chromatin to amplify heterochromatic siRNA2012
- Author(s)
  Kawakami K, Hayashi A, Nakayama J, & Murakami Y
- Journal Title
  
  Genes Dev
  
  Volume: 26 Issue: 16 Pages: 811-1824
- DOI
  10.1101/gad.190272.112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370004, KAKENHI-ORGANIZER-23114001, KAKENHI-PLANNED-23114005, KAKENHI-PUBLICLY-23114701
[Journal Article] Roles of fission yeast Grc3 protein in ribosomal RNA processing and heterochromatic gene silencing2011
- Author(s)
  Jun-ichi Nakayama
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 286 Issue: 17 Pages: 15391-402
- DOI
  10.1074/jbc.m110.201343
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22115513, KAKENHI-PROJECT-23370004
[Presentation] HP1/Swi6 Acts in Concert with Ers1 to Regulate RNAi-directed Heterochromatin Assembly2012
- Author(s)
  Aki Hayashi
- Organizer
  22nd CDB meeting: RNA Sciences in Cell and Developmental Biology II
- Place of Presentation
  CDB, Kobe
- Data Source
  KAKENHI-PROJECT-22570176
[Presentation] Ers1はHP1を介してRNAi機構をヘテロクロマチンにリクルートする2012
- Author(s)
  林亜紀
- Organizer
  第４５回酵母遺伝学フォーラム
- Place of Presentation
  きはだホール・宇治
- Data Source
  KAKENHI-PROJECT-22570176
[Presentation] Ers1はHP1を介してRNAi機構をヘテロクロマチンにリクルートする2012
- Author(s)
  林亜紀
- Organizer
  第45回酵母遺伝学フォーラム
- Place of Presentation
  宇治(口頭)
- Data Source
  KAKENHI-PROJECT-22570176
[Presentation] Ers1因子はHP1を介してヘテロクロマチン上にRNAi機構をリクルートする2012
- Author(s)
  林亜紀
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  博多(口頭)
- Data Source
  KAKENHI-PROJECT-22570176
[Presentation] HP1/Swi6 Acts in Concert with Ers1 to Regulate RNAi-directed Heterochromatin Assembly2012
- Author(s)
  Aki Hayashi
- Organizer
  22^<nd> CDB meeting: RNA Sciences in Cell and Developmental Biology II
- Place of Presentation
  Kobe(oral)
- Data Source
  KAKENHI-PROJECT-22570176
[Presentation] Ers1因子はHP1を介してヘテロクロマチン上にRNAi機構をリクルートする2012
- Author(s)
  林亜紀
- Organizer
  日本遺伝学会第８４回大会
- Place of Presentation
  九大百年講堂・博多
- Data Source
  KAKENHI-PROJECT-22570176
[Presentation] Ers1 links heterochromatin and RNAi machinery2011
- Author(s)
  Aki Hayashi
- Organizer
  The Sixth International Fission Yeast Meeting
- Place of Presentation
  Harvard Medical School (Boston, U.S.A.,)
- Year and Date
  2011-06-26
- Data Source
  KAKENHI-PROJECT-22570176
[Presentation] HP1/Swi6 acts in concert with Ers1 to drive RNAi-directed heterochromatin assembly2011
- Author(s)
  林亜紀
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜(口頭+ポスター)
- Data Source
  KAKENHI-PROJECT-22570176
[Presentation] 分裂酵母ヘテロクロマチン形成とRNAi機構のリンク2011
- Author(s)
  林亜紀・石田真由美・中山潤一
- Organizer
  第28回染色体ワークショップ
- Place of Presentation
  瑠璃光・石川県加賀市
- Year and Date
  2011-01-13
- Data Source
  KAKENHI-PROJECT-22570176
[Presentation] HP1/Swi6はErs1を介してRNAi機構によるヘテロクロマチン形成を促進する2011
- Author(s)
  林亜紀
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22570176
[Presentation] Ers1 links heterochromatin and RNAi machinery2011
- Author(s)
  Aki Hayashi.
- Organizer
  6th International Fission Yeast Meeting
- Place of Presentation
  Boston, U.S.A.(poster)
- Data Source
  KAKENHI-PROJECT-22570176
[Presentation] 分裂酵母ヘテロクロマチン形成とRNAi機構のリンク2011
- Author(s)
  林亜紀
- Organizer
  第28回染色体ワークショップ
- Place of Presentation
  山代(口頭)
- Data Source
  KAKENHI-PROJECT-22570176

1. NAKAYAMA Jun-ichi (60373338)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. Tanaka Katsunori (60273926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 村上洋太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 西村善文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hayashi Aki 林 亜紀

HAYASHI Aki 林 亜紀

Research Projects

Research Products

Co-Researchers

The search for the novel safeguard system to maintain the telomere length

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

RNAi機構が介するヘテロクロマチン形成を制御する細胞内事象メカニズムの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The molecular mechanisms of heterochromatin establishment and maintenance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the mechanism of histone methylation by using genetic approachesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A novel RNAi protein, Dsh1, assembles RNAi machinery on chromatin to amplify heterochromatic siRNA2012

Author(s)

Journal Title

Data Source

[Journal Article] Two different RFC proteins, Ctf18 and RFC1 separately control PCNA-CRL4Cdt2-mediated Cdt1 proteolysis during S phase and following UV-irradiation2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intrinsic nucleic acid-binding activity of Chp1 chromodomain is required for heterochromatin assembly2012

Author(s)

Journal Title

Data Source

[Journal Article] Heterochromatin protein 1 homologue Swi6 acts in concert with Ers1 to regulate RNAi-directed heterochromatin assembly2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heterochromatin protein 1 homologue Swi6 acts in concert with Ers1 to regulate RNAi-directed heterochromatin assembly2012

Author(s)

Journal Title

Data Source

[Journal Article] Intrinsic Nucleic Acid-Binding activity of Chp1 Chromodomain Is Required for Heterochromatic Gene Silencing2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel RNAi protein, Dsh1, assembles RNAi machinery on chromatin to amplify heterochromatic siRNA2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Roles of fission yeast Grc3 protein in ribosomal RNA processing and heterochromatic gene silencing2011

Author(s)

Journal Title

DOI

Data Source

[Presentation] HP1/Swi6 Acts in Concert with Ers1 to Regulate RNAi-directed Heterochromatin Assembly2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Ers1はHP1を介してRNAi機構をヘテロクロマチンにリクルートする2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Ers1はHP1を介してRNAi機構をヘテロクロマチンにリクルートする2012

Author(s)

Organizer

Place of Presentation

Hayashi Aki 林亜紀

HAYASHI Aki 林亜紀