MITSUHASI Noboru 三橋登

Researcher Number	80400985
Affiliation (based on the past Project Information) *help	2007 – 2009: Chiba University, Research Center for Frontier Medical Engineering, Associate Professor 2008: 千葉大学, フトンティアメディカル工学研究開発センター, 准教授 2008: 千葉大学, フロンティアメディカルセンター, 准教授 2008: 千葉大学, フロンティアメディカル工学研究開発センター, 准教授 2007: 千葉大学, フロンティアメディカル工学研究センター, 准教授 2006: 千葉大学, フロンティアメディカル工学研究開発センター, 助教授
Review Section/Research Field	Principal Investigator General surgery Except Principal Investigator Digestive surgery / General surgery
Keywords	Principal Investigator AFP / VEGF / Homing / Bone Marrow Stem Cell / ホーミング / 骨髄幹細胞 Except Principal Investigator 癌 / 肝切除 / 血管内皮前駆細胞 / 類洞内皮細胞 … More / 肝再生 / 細胞・組織 / 組織 / 細胞 / 再生医学 / 遺伝子 / 間葉系細胞 / シグナル伝達 / 遣伝子 / 細胞浸潤能 / 細胞遊走能 / 間質細胞 / FGFR2 / FGF10 / 膵臓癌 / 消化器癌 / 実験外科学 Less

Evaluation of the signal transduction that controls hepatic sinusoidal regeneration and attempt to promote liver regeneration using endothelial progenitor cells.
- Principal Investigator
  
  SHIMIZU Hiroaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
Mechanismsoftheinteractionbetweencancercells andmesenchymal Cells in gastroirltestinal cancer.
- Principal Investigator
  
  YOSHLTOML Hldeyukl
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Chiba University
Antitumor effects and promotion of liver regeneration by controlling angiogenetic signal transduction
- Principal Investigator
  
  SHIMIZU Shimizu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
A Novel Gene Therapy with Bone Marrow Stem Cell HomingPrincipal Investigator
- Principal Investigator
  
  MITSUHASHI Noboru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Chiba University

All 2012 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinoma2012
- Author(s)
  Miura S, Mitsuhashi N, Shimizu H, Kimura F, Yoshidome H, Ohtsuka M, Kato A, Shida T, Okamura D, Miyazaki M
- Journal Title
  
  BMC Cancer
  
  Volume: 12 Pages: 56-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591744
[Journal Article] Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinoma2012
- Author(s)
  Miura S, Mitsuhashi N, Shimizu H, et al.
- Journal Title
  
  BMC Cancer
  
  Volume: 6 Pages: 56-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591744
[Journal Article] Induction of antitumor response by in vivo allogeneic major histocompatibility complex gene transfer using electroporation2009
- Author(s)
  Shimizu H, Nukui Y, Mitsuhashi N, Kimura F, Yoshidome H, Ohtsuka M, Kato A, Miyazaki M
- Journal Title
  
  J Surg Res
  
  Volume: 154 Pages: 60-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591744
[Journal Article] Preoperative GATA3 mRNA expression in peripheral blood mononuclear cells is up-regulated in patients with postoperative infection following hepatobiliary pancreatic surgery2008
- Author(s)
  kawamoto J, Kimura F, Yoshitomi H, Shimizu H, Yoshidome H, Ohtsuka M, Kato A, Nozawa S, Furukawa K, Mitsuhashi N, Takeuchi D, Miyazaki M
- Journal Title
  
  J Surg Res(Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591503
[Journal Article] Clinical significance of a-Fetoprotein ; involvement on proliferation, angiogenesis, and apoptosis of hepatocellular carcinoma2008
- Author(s)
  Mitsuhashi N, Kobayashi S, Doki T, Kimura F, Shimizu H, Yoshidome H, Ohtsuka M, Kato A, Yoshitomi H, Nozawa S, Furukawa K, Takeuchi D, Suda K, Miura S, Miyazaki M.
- Journal Title
  
  J Gastroenterol Hepatol 23
  
  Pages: 189-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591503
[Journal Article] Angiopoietin-2 levels ithe hepatic vein as a useful predictor of tumor invasiveness and prognosis in human hepatocellular carcinoma2008
- Author(s)
  Kuboki S, Shimizu H, Mitsuhashi N, Kusashio K, Kimura F, Yoshidome H, Ohtsuka M, Kato A, Yoshitomi H, Miyazaki M
- Journal Title
  
  J Gastroenterol Hepatol 23
  
  Pages: 157-164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591503
[Journal Article] Angiopoietin-2 levels in the hepatic vein as a useful predictor of tumor invasiveness and prognosis in human hepatocellular carcinoma2008
- Author(s)
  Kuboki S, Shimizu H, Mitsuhashi N, Kusashio K, Kimura F, Yoshidome H, Ohtsuka M, Kato A, Yoshitomi H, Miyazaki M
- Journal Title
  
  J Gastroenterol Hepatol 23
  
  Pages: 157-64
- Data Source
  KAKENHI-PROJECT-19591575
[Journal Article] Rat chemokine CXCLll: structure, tissue distribution, function and expression incardiac transplantation models.2007
- Author(s)
  Noboru Mitsuhashi, et. al.
- Journal Title
  
  Mol Cell Biochem. 296
  
  Pages: 1-9
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591431
[Journal Article] Rat chemokine CXCL11: structure, tissue distribution, function and expression in cardiac transplantation models2007
- Author(s)
  Noboru Mitsuhashi, et. al.
- Journal Title
  
  Mol Cell Biochem 296
  
  Pages: 1-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591431
[Journal Article] Aggressive surgical approach for Stage IV gallbladder carcinoma based on Japanese Society of Biliary Surgery Classification2007
- Author(s)
  Shimizu H, Kimura F, Yoshidome F, Ohtsuka M, Kato A, Yoshitomi H, Nozawa S, Furukawa K, Mitsuhashi M, Takeuchi D,Suda K, Miyazaki M
- Journal Title
  
  J Hepatobiliary Pancreat Surg 14
  
  Pages: 358-365
- Data Source
  KAKENHI-PROJECT-19591575
[Journal Article] Clinical significance of α-Fetoprotein; involvement on proliferation, angiogenesis, and apoptosis of hepatocellular carcinoma
- Author(s)
  Noboru Mitsuhashi, et. al.
- Journal Title
  
  J Gastroenterol Hepatol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591431
[Journal Article] Clinical significance of α-Fetoprotein; involvement on proliferation, angiogenesis, and apoptosis of hepatocellular carcinoma
- Author(s)
  Noboru Mitsuhashi, et. al.
- Journal Title
  
  J Gastroenterol Hepatol. (In press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591431
[Presentation] 膵癌分子標的治療薬としてのAnnexinII臨床応用への挑戦2008
- Author(s)
  高野重紹、吉富秀幸、外川明、志田崇、木村文夫、清水宏明、吉留博之、大塚将之、加藤厚、野澤聡志、古川勝規、三橋登、竹内男、高屋敷吏、須田浩介、野村文夫、宮崎勝
- Organizer
  第108回日本外科学会定期学術集会
- Place of Presentation
  長崎
- Year and Date
  2008-05-18
- Data Source
  KAKENHI-PROJECT-19591503
[Presentation] FGFIO/FGFR2-IIIbsignalを介した膵癌細胞遊走浸潤能の誘導2008
- Author(s)
  野村悟、吉富秀幸、高野重紹、志田崇、小林壮一、木村文夫、清水宏明、吉留博之、大塚将之、加藤厚、野澤聡志、古川勝規、三橋登、竹内男、高屋敷吏、須田浩介、宮崎勝
- Organizer
  第108回日本外科学会定期学術集会
- Place of Presentation
  長崎
- Year and Date
  2008-05-18
- Data Source
  KAKENHI-PROJECT-19591503
[Presentation] 勝FGF10およびFGFR2-IIIbのシグナルを介した膵癌における細胞遊走浸潤能の誘導2008
- Author(s)
  野村悟、吉富秀幸、高野重紹、志田崇、小林壮一、木村文夫、清水宏明、吉留博之、大塚将之、加藤厚、野澤聡志、古川勝規、三橋登、竹内男、高屋敷吏、須田浩介、宮崎勝
- Organizer
  第63回日本消化器外科学会
- Place of Presentation
  札幌
- Year and Date
  2008-07-17
- Data Source
  KAKENHI-PROJECT-19591503
[Presentation] Significance of AFP expression in Hepatocellular Carcinoma2007
- Author(s)
  Noboru Mitsuhashi, et. al.
- Organizer
  Annual Congress of Liver Cancer Study Group ofJapan 43rd
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2007-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591431
[Presentation] Alpha-fetoprotein in Hepatocelular Carcinoma2007
- Author(s)
  Noboru Mitsuhashi, et. al.
- Organizer
  Annual Congress of Japanese Society of Gastroenterological Surgery 62nd
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2007-07-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591431
[Presentation] VEGF, PIGF/VEGFR-1システムは間葉系幹細胞の同種移植心へのホーミングと増殖に関与する2007
- Author(s)
  三橋登他
- Organizer
  第107回日本外科学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-04-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591431
[Presentation] Involvement of VEGF, P1GF/VEGFR-1 system in Mesenchymal Stem Cell homing to allogeneic heart graft2007
- Author(s)
  Noboru Mitsuhashi, et. al.
- Organizer
  Annual Congress of Japan Surgical Society 108th
- Place of Presentation
  Osaka, Japan
- Year and Date
  2007-04-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591431
[Presentation] Small Interfering RNA Administration against AFP Inhibits Proliferation and Anti-apoptotic Properties of Hepatocellular Carcinoma Cell Lines.2007
- Author(s)
  Noboru Mitsuhashi, et. al.
- Organizer
  European Cancer Conference 14th (ECCO14)
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2007-09-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591431
[Presentation] Small Interfering RNA Administration against AFP Inhibits Proliferation and Anti-apoptotic Properties of Hepatocellular Carcinoma Cell Lines2007
- Author(s)
  Noboru Mitsuhashi, et. al.
- Organizer
  European Cancer Conference 14th
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2007-09-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591431
[Presentation] VEGF,PIGF/VEGFR-1システムは間葉系幹細胞の同種移植心へのホーミングと増殖に関与する2007
- Author(s)
  三橋登, 他
- Organizer
  第107回日本外科学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-04-12
- Data Source
  KAKENHI-PROJECT-18591431
[Presentation] 肝細胞癌還流領域の肝静脈血のAngiopoietin-2値と測定の意義 : 予後因子としての肝静脈血Angiopoietin-2の有用性について.2007
- Author(s)
  清水宏明、木村文夫、吉留博之、大塚將之、加藤厚、吉富秀幸、野沢聡志、古川勝規、三橋登、竹内男、須田浩介、吉岡伊作、宮崎勝
- Organizer
  第107回日本外科学会定期学術集会
- Place of Presentation
  大阪
- Year and Date
  2007-04-11
- Data Source
  KAKENHI-PROJECT-19591575
[Presentation] 肝細胞癌におけるAFPの役割2007
- Author(s)
  三橋登他
- Organizer
  第62回日本消化器外科学会総会
- Place of Presentation
  東京
- Year and Date
  2007-07-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591431
[Presentation] 肝細胞癌におけるAFP発現の意義と発現制御の基礎的検討2007
- Author(s)
  三橋登他
- Organizer
  第43回日本肝癌研究会
- Place of Presentation
  東京
- Year and Date
  2007-06-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591431
[Presentation] Small Interfering RNA Administration against AFP Inhibits Proliferation and Anti-apoptotic Properties of Hepatocellular Carcinoma Cell Lines.2007
- Author(s)
  Noboru Mitsuhashi, et. al.
- Organizer
  European Cancer Conference 14th(ECCO14)
- Place of Presentation
  Barcelona,Spain
- Year and Date
  2007-09-24
- Data Source
  KAKENHI-PROJECT-18591431

1. OHTSUKA Masayuki (90334185)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
2. MIYAZAKI Masaru (70166156)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
3. SUDA Kosuke (50400908)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. SHIMIZU Shimizu (80272318)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
5. KIMURA Fumio (70334208)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
6. YOSHLTOML Hldeyukl (60375631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. TAKANO Shigetsugu (20436380)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. YOSHIDOME Hiroyuki (10312935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MITSUHASI Noboru 三橋 登

Research Projects

Research Products

Co-Researchers

Evaluation of the signal transduction that controls hepatic sinusoidal regeneration and attempt to promote liver regeneration using endothelial progenitor cells.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanismsoftheinteractionbetweencancercells andmesenchymal Cells in gastroirltestinal cancer.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Antitumor effects and promotion of liver regeneration by controlling angiogenetic signal transduction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A Novel Gene Therapy with Bone Marrow Stem Cell HomingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinoma2012

Author(s)

Journal Title

Data Source

[Journal Article] Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinoma2012

Author(s)

Journal Title

Data Source

[Journal Article] Induction of antitumor response by in vivo allogeneic major histocompatibility complex gene transfer using electroporation2009

Author(s)

Journal Title

Data Source

[Journal Article] Preoperative GATA3 mRNA expression in peripheral blood mononuclear cells is up-regulated in patients with postoperative infection following hepatobiliary pancreatic surgery2008

Author(s)

Journal Title

Data Source

[Journal Article] Clinical significance of a-Fetoprotein ; involvement on proliferation, angiogenesis, and apoptosis of hepatocellular carcinoma2008

Author(s)

Journal Title

Data Source

[Journal Article] Angiopoietin-2 levels ithe hepatic vein as a useful predictor of tumor invasiveness and prognosis in human hepatocellular carcinoma2008

Author(s)

Journal Title

Data Source

[Journal Article] Angiopoietin-2 levels in the hepatic vein as a useful predictor of tumor invasiveness and prognosis in human hepatocellular carcinoma2008

Author(s)

Journal Title

Data Source

[Journal Article] Rat chemokine CXCLll: structure, tissue distribution, function and expression incardiac transplantation models.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Rat chemokine CXCL11: structure, tissue distribution, function and expression in cardiac transplantation models2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Aggressive surgical approach for Stage IV gallbladder carcinoma based on Japanese Society of Biliary Surgery Classification2007

Author(s)

Journal Title

Data Source

[Journal Article] Clinical significance of α-Fetoprotein; involvement on proliferation, angiogenesis, and apoptosis of hepatocellular carcinoma

Author(s)

Journal Title

Description

Data Source

[Journal Article] Clinical significance of α-Fetoprotein; involvement on proliferation, angiogenesis, and apoptosis of hepatocellular carcinoma

Author(s)

Journal Title

Description

Data Source

MITSUHASI Noboru 三橋登