KAWAGUCHI Yoshihiko 河口賀彦

… Alternative Names

河口賀彦カワグチヨシヒコ

Less

Researcher Number	80402048
Other IDs
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 講師
Affiliation (based on the past Project Information) *help	2021 – 2022: 山梨大学, 大学院総合研究部, 講師 2020: 山梨大学, 大学院総合研究部, 助教 2014: 山梨大学, 総合研究部, 助教 2012 – 2013: 山梨大学, 医学工学総合研究部, 助教 2011 – 2012: 山梨大学, 大学院・医学工学総合研究部, 助教 … More 2010: 山梨大学, 医学部・付属病院, 診療助教 2010: 山梨大学, 医学部・附属病院, 診療助教 2009 – 2010: University of Yamanashi, 医学部附属病院, 診療助教 2008: University of Yamanashi, 医学部・附属病院, 医員 2007 – 2008: University of Yamanashi, Hospital, Medical Official Less
Review Section/Research Field	Principal Investigator Digestive surgery Except Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator 抗体療法 / 食道扁平上皮癌 / 抗体依存性細胞障害 / Herceptin / trastuzumab / 抗HER3抗体 / HER2 / HER3 / granzyme / perforin … More / ADCC / 細胞障害活性 / Trastuzumab / 抗体依存性細胞傷害 … More Except Principal Investigator 癌ワクチン療法 / 胃癌 / 食道癌 / exosome / 血球細胞 / 消化器癌 / 悪性度 / 膵液漏 / 膵臓癌 / 血小板 / 癌悪性度 / Esophageal cancer / Cancer vaccination / 樹状細胞 / Th2 / Th1 / Th17細胞 / ノックアウトマウス / 酸化ストレス / アポトーシス / 制御性T細胞 / IL-17 / 癌微小環境 / Foxp3 / Treg / Th17 / 癌免疫療法 / 胃十二指腸外科学 / 癌拒絶抗原 / 免疫療法 / ペプチドワクチン / 食道がん / 食道扁平上皮がん / Cancer-testis抗原 / ペプチド抗原 Less

Elucidation of the mechanism of hematopoietic cell-mediated cancer progression in gastrointestinal cancer and development of new treatment methods
- Principal Investigator
  
  Ichikawa Daisuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  University of Yamanashi
Development of the anti-HER3 antibody therapy for esophageal squamous cell carcinoma.Principal Investigator
- Principal Investigator
  
  KAWAGUCHI Yoshihiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Yamanashi
Distribution of Th17 cells related to regulatory T cells withintumor-microenvironment in cancer-bearing hosts.
- Principal Investigator
  
  MIZUKAMI Yoshiki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Yamanashi
Mechanisms of escape from trastuzumab-mediated ADCC in esophageal squamous cell carcinoma.Principal Investigator
- Principal Investigator
  
  KAWAGUCHI Yoshihiko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Yamanashi
Development of Cancer Vaccination with Multiple Peptides derived from Novel Cancer-Testis Antigens against esophageal cancer
- Principal Investigator
  
  KONO Koji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Yamanashi
Mechanisms of escape from trastuzumab-mediated ADCC in esophageal squamous cell carcinoma.Principal Investigator
- Principal Investigator
  
  KAWAGUCHI Yoshihiko
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Yamanashi
Cancer vaccination therapy for gastric and esophageal cancer as an adjuvant setting after resection
- Principal Investigator
  
  KONO Koji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Yamanashi

All 2022 2021 2020 2012 2011 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Soluble podoplanin as a biomarker in diffuse type gastric cancer.2022
- Author(s)
  Takiguchi K, Shoda K, Nakayama T, Takahashi K, Saito R, Yamamoto A, Furuya S, Akaike H, Hosomura N, Kawaguchi Y, Amemiya H, Kawaida H, Inoue S, Kono H, Konishi H, Otsuji E, Ichikawa D.
- Journal Title
  
  Oncology Reports
  
  Volume: 47 Issue: 3 Pages: 51-51
- DOI
  10.3892/or.2022.8262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09031
[Journal Article] Platelets enhance malignant behaviours of gastric cancer cells via direct contacts.2021
- Author(s)
  Saito R, Shoda K, Maruyama S, Yamamoto A, Takiguchi K, Furuya S, Hosomura N, Akaike H, Kawaguchi Y, Amemiya H, Kawaida H, Sudo M, Inoue S, Kono H, Suzuki-Inoue K, Ichikawa D.
- Journal Title
  
  British Journal of Cancer
  
  Volume: 124 Issue: 3 Pages: 570-573
- DOI
  10.1038/s41416-020-01134-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09031
[Journal Article] Exposure to Blood Components and Inflammation Contribute to Pancreatic Cancer Progression2021
- Author(s)
  Saito Ryo、Kawaida Hiromichi、Hosomura Naohiro、Amemiya Hidetake、Itakura Jun、Yamamoto Atsushi、Takiguchi Koichi、Maruyama Suguru、Shoda Katsutoshi、Furuya Shinji、Akaike Hidenori、Kawaguchi Yoshihiko、Sudo Makoto、Inoue Shingo、Kono Hiroshi、Ichikawa Daisuke
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 28 Issue: 13 Pages: 8263-8272
- DOI
  10.1245/s10434-021-10250-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09031
[Journal Article] Lapatinib inhibits receptor phosphorylation and cell growth and enhances antibody dependent cellular cytotoxicity (ADCC) of EGFR and HER2 over-expressing esophageal cancer cell lines.2011
- Author(s)
  Kousaku Mimura, Koji Kono, Takanori Maruyama, Mitsuaki Watanabe, Shinichiro Izawa, Shugo Shiba, Yoshiki Mizukami, Yoshihiko Kawaguchi, Masayuki Inoue, Tetsuo Kono, Aniruddha Choudhury, Rolf Kiessling, Hideki Fujii.
- Journal Title
  
  Int J Cancer.[Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591566
[Journal Article] Lapatinib inhibits receptorphosphorylation and cell growth andenhances antibody dependent cellularcytotoxicity(ADCC) of EGFR and HER2over-expressing esophageal cancercell lines2011
- Author(s)
  Mimura K, Kono K, MizukamiY, Kawaguchi Y
- Journal Title
  
  Int J Cancer.
  
  Volume: 129(10) Pages: 2408-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591452
[Journal Article] Immunonutritional diet modulatesnatural killer cell activation andTh17 cell distribution in patientswith gastric and esophageal cancer2011
- Author(s)
  Maruyama T, Kawaguchi Y, Kono K
- Journal Title
  
  Nutrition
  
  Volume: 27(2) Pages: 146-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591452
[Journal Article] Immunonutritional diet modulates NK cell activation and Th17 cell distribution in patients with gastric and esophageal cancer.2011
- Author(s)
  Takanori Maruyama, Kousaku Mimura, Shinichiro Izawa, Shugo Shiba, Mitsuaki Watanabe, Yoshihiko Kawaguchi, Hideki Fujii, Koji Kono.
- Journal Title
  
  Nutrition. 27(2)
  
  Pages: 146-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591566
[Journal Article] Lapatinib inhibits receptor phosphorylation and cell growth and enhances antibody dependent cellular cytotoxicity(ADCC) of EGFR and HER2 over-expressing esophageal cancer cell lines2011
- Author(s)
  Mimura K, Kono K, Maruyama T, WatanabeM, Izawa S, Shiba S, Mizukami Y, Kawaguchi Y, Inoue M, Kono T, Choudhury A, Kiessking R, and Fujii H
- Journal Title
  
  Int J Cancer
  
  Volume: 29(10) Pages: 2408-2416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791268
[Journal Article] Lapatinib enhances Hercep tin-mediated antibody-dependent cellu lar cytotoxicity by up-regulation of cell surface HER2 expression2011
- Author(s)
  Maruyama T, Mimura K, Izawa S, InoueA, Shiba S, Watanabe M, Kawaguchi Y, Inoue M, Nogata H, Inoue S, Fujii H, and Kono K
- Journal Title
  
  Anticancer Res
  
  Volume: 31(9) Pages: 2999-3005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791268
[Journal Article] Distribution of Th17 cells and Foxp3(+) regulatory T cells intumor-infiltrating lymphocytes,tumor draining lymph nodes andperipheral blood lymphocytes inpatients with gastric cancer2010
- Author(s)
  Maruyama T, Kono K, Mizukami Y,Kawaguchi Y, Fujii H
- Journal Title
  
  Cancer Science
  
  Volume: 101(9) Pages: 1947-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591452
[Journal Article] Inverse correlation of HER2 with MHC class I expression on oesophageal squamous cell carcinoma2010
- Author(s)
  Maruyama T, Mimura K, Sato E, Watanabe M, Mizukami Y, Kawaguchi Y, Ando T, Kinouchi H, Fujii H, and Kono K
- Journal Title
  
  Br J Cancer
  
  Volume: 103巻 Pages: 552-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791268
[Journal Article] CCL17 and CCL22 chemokines withintumor microenvironment are related toinfiltration of regulatory T cells inesophageal squamous cell carcinoma2010
- Author(s)
  Maruyama T, Kono K, Mizukami Y,Kawaguchi Y, Fujii H
- Journal Title
  
  Disease Esophagus
  
  Volume: 23(5) Pages: 422-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591452
[Journal Article] Distribution of Th17 cells and FoxP3(+) regulatory T cells in tumor-infiltrating lymphocytes, tumor-draining lymph nodes, and peripheral blood lymphocytes in patients with gastric cancer.2010
- Author(s)
  Takanori Maruyama, Koji Kono, Yoshiki Mizukami, Yoshihiko Kawaguchi, Kousaku Mimura, Mitsuaki Watanabe, Shinichirou Izawa, Hideki Fujii.
- Journal Title
  
  Cancer Science 101(9)
  
  Pages: 1947-1954
- NAID
  10027831238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591566
[Journal Article] Interleukin-21 can efficiently restore impaired antibody-dependent cell-mediated cytotoxicity in patients with oesophageal squamous cell carcinoma2010
- Author(s)
  Watanabe M, Kono K, Kawaguchi Y, Mizukami Y, Mimura K, Maruyama T, Fujii H
- Journal Title
  
  Br J Cancer
  
  Volume: 102巻 Pages: 520-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791268
[Journal Article] CCL17 and CCL22 Chemokines within Tumor Microenvironment are Related to Infiltration of Regulatory T Cells in Esophageal Squamous Cell Carcinoma.2010
- Author(s)
  Takanori Maruyama, Koji Kono, Shinichirou Izawa, Yoshiki Mizukami, Yoshihiko Kawaguchi, Kousaku Mimura, Mitsuaki Watanabe, Hideki Fujii.
- Journal Title
  
  Disease of the Esophagus. 23(5)
  
  Pages: 422-429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591566
[Journal Article] Interleukin-21 can efficiently restore impaired antibody-dependent cell-mediated cytotoxicity in patients with esophageal squamous cell carcinoma.2010
- Author(s)
  Mitsuaki Watanabe, Koji Kono, Yoshihiko Kawaguchi, Yoshiki Mizukami, Kousaku Mimura, Takanori Maruyama, Hideki Fujii.
- Journal Title
  
  Br J Cancer. 102(3)
  
  Pages: 520-529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591566
[Journal Article] NK cell dysfunction with down-regulated CD16 and up-regulated CD56 molecules in patients with esophageal squamous cell carcinoma.2010
- Author(s)
  Mitsuaki Watanabe, Koji Kono, Yoshihiko Kawaguchi, Yoshiki Mizukami, Kousaku Mimura, Takanori Maruyama, Shinichirou Izawa, Hideki Fujii
- Journal Title
  
  Disease of the Esophagus 23(8)
  
  Pages: 675-681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591566
[Journal Article] Inverse correlation of HER2 with MHC class I expression on esophageal squamous cell carcinoma.2010
- Author(s)
  Takanori Maruyama, Kousaku Mimura, Eiji Sato, Mitsuaki Watanabe, Yoshiki Mizukami, Yoshihiko Kawaguchi, Takashi Ando, Hiroyuki Kinouchi, Hideki Fujii, Koji Kono.
- Journal Title
  
  British Journal of Cancer 103
  
  Pages: 552-559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591566
[Journal Article] Mechanisms of escape from trastuzumab-mediated ADCC in esophageal squamorscell carcinoma.2009
- Author(s)
  Yoshihiko Kawaguchi
- Journal Title
  
  Anticancer Res. 29
  
  Pages: 2137-2146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790947
[Journal Article] Mechanisms of escape from trastuzumab-mediated ADCC in esophageal squamous cell carcinoma.2009
- Author(s)
  Yoshihiko Kawaguchi
- Journal Title
  
  Anticancer Res. 29
  
  Pages: 2137-2146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591566
[Journal Article] Hideki Fujii Mechanisms of escape from trastuzumab-mediated ADCC in esophageal squamous cell carcinoma : Relation to susceptibility to perforin-granzyme.2009
- Author(s)
  Yoshihiko Kawaguchi, Koji Kono, Yoshiki Mizukami, Kousaku Mimura
- Journal Title
  
  Anticancer Res. 29(6)
  
  Pages: 2137-2146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591566
[Journal Article] Mechanisms of escape from Trastuzumab-mediated ADCC in esophageal squamous cell carcinoma: Relation to susceptibility to perforin-granzyme.2009
- Author(s)
  Kawaguchi Y, Kono K, Mizukami Y, Mimura K, Fujii H
- Journal Title
  
  Anticancer Res. 29
  
  Pages: 2137-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790947
[Journal Article] Vaccination with multiple peptides derived from novel cancer-testis antigens can induce specific T-cell responses and clinical responses in advanced esophageal cancer.2009
- Author(s)
  Kono K, Mizukami Y, Daigo Y, Takano A, Masuda K, Yoshida K, Tsunoda T, Kawaguchi Y, Nakamura Y, Fujii H
- Journal Title
  
  Cancer Sci 100(8)
  
  Pages: 1502-9
- NAID
  10027193584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790947
[Journal Article] Vaccination with Multiple Peptides derived from Novel Cancer-Testis Antigens Can Induce Specific T-Cell Responses and Clinical Responses in Advanced Esophageal cancer.2009
- Author(s)
  Koji Kono, Yoshiki Mizukami, Yataro Daigo, Atsushi Takano, Ken Masuda, Koji Yoshida, Takuya Tsunoda, Yoshihiko Kawaguchi, Yusuke Nakamura, Hideki Fujii
- Journal Title
  
  Cancer Sci. 100(8)
  
  Pages: 1502-1509
- NAID
  10027193584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591566
[Journal Article] Protein-bound polysaccharide K partially prevents apoptosis of circulating T cells induced by anti-cancer drug S-1 in patients with gastric cancer.2008
- Author(s)
  Kono K, Kawaguchi Y, Mizukami Y, Mimura K, Sugai H, Akaike H, Fujii H
- Journal Title
  
  Oncology 74(3-4)
  
  Pages: 143-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790947
[Journal Article] CCL17 and CCL22 chemokines within Tumor Microenvironment are related to Accumulation of Foxp3^+ Regulatory T cells in Gastric Cancer.2008
- Author(s)
  Yoshiki Mizukami, Koji Kono, Yoshihiko Kawaguchi, Hidemitsu Sugai, et. al.
- Journal Title
  
  International Journal of Cancer 122
  
  Pages: 2286-2293
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591459
[Journal Article] Detection of novel Cancer-Testis antigen-specific T-cell responses in TIL, regional lymph nodes and PBL in patients with esophageal squamous cell carcinoma.2008
- Author(s)
  Yoshiki Mizukami, Koji Kono, Yataro Daigo, Atsushi Takano, Takuya Tsunoda, Yoshihiko Kawaguchi, Yusuke Nakamura, Hideki Fujii.
- Journal Title
  
  Cancer Science 99(7)
  
  Pages: 1448-1454
- NAID
  10024008885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591566
[Journal Article] Down-regulation of HLA Class I molecules in the tumor is associated with a poor prognosis in patients with esophageal squamous cell carcinoma.2008
- Author(s)
  Yoshiki Mizukami, Koji Kono, Takanori Maruyama, Mitsuaki Watanabe, Yoshihiko Kawaguchi, Kazuyasu Kamimura, Hideki Fujii
- Journal Title
  
  British Journal of Cancer 4;99(9)
  
  Pages: 1462-1467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591566
[Journal Article] Localisation pattern of Foxp3+ regulatory T cell is associated with clinical behaviour in gastric cancer.2008
- Author(s)
  Mizukami Y, Kono K, Kawaguchi Y, Akaike H, Kamimura K, Sugai H, Fujii H
- Journal Title
  
  Br J Cancer 98(1)
  
  Pages: 148-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790947
[Journal Article] Protein-bound polysaccharide K (PSK) partially prevents apoptosis of circulating T cells induced by anti-cancer drug S-1 in patients with gastric2008
- Author(s)
  Koji Kono, Yoshihiko Kawaguchi, Yoshiki Mizukami, Kousaku Mimura, Hidemitsu Sugai, Hidenori Akaike, Hideki Fujii
- Journal Title
  
  cancer Oncology 74
  
  Pages: 143-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591566
[Journal Article] CCL17 and CCL22 chemokines within Tumor Microenvironment are related to Accumulation of Foxp3^+ Regulatory T cells in Gastric Cancer.2008
- Author(s)
  Yoshiki Mizukami, Koji Kono, Yoshihiko Kawaguchi, Hidenori Akaike, Kazuyasu Kamimura, Hidemitsu Sugai, Hideki Fujii
- Journal Title
  
  International Journal of Cancer 122(10)
  
  Pages: 2286-2293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591566
[Journal Article] Detection of novel cacer-testis antigen-specific T-cell responses in TIL, regional lymph nodes, and PBL in patients with esophageal squamous cell carinoma.2008
- Author(s)
  Mizukami Y, Kono K, Daigo Y, Takano A, Tsunoda T, Kawaguchi Y, Nakamura Y, Fujii H
- Journal Title
  
  Cancer Sci 99(7)
  
  Pages: 1448-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790947
[Journal Article] CCL17 and CCL22 chemokines within Tumor Microenvironment are related to Accumulation of Foxp3^+ Regulatory T cells in Gastric Cancer2008
- Author(s)
  Yoshiki, Mizukami, Koji, Kono, Yoshihiko, Kawaguchi, Hidemitsu, Sugai
- Journal Title
  
  International Journal of Cancer 122
  
  Pages: 2286-2293
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591459
[Journal Article] Downregulation of HLA Class I molecules in the tumor is associated with a poor prognosis in patients with oesophageal squamous cell carcinoma.2008
- Author(s)
  Mizukami Y, Kono K, Maruyama T, Watanabe M, Kawaguchi Y, Kamimura K, Fujii H
- Journal Title
  
  Br J Cancer 99(9)
  
  Pages: 1462-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790947
[Journal Article] Localization Pattern of Foxp3^+ Regulatory T cells is associated with Clinical Behavior in Gastric Cancer.2008
- Author(s)
  Yoshiki Mizukami, Koji Kono, Yoshihiko Kawaguchi, Hidenori Akaike, Kazuyasu Kamimura, Hidemitsu Sugai, Hideki Fujii
- Journal Title
  
  British Journal of Cancer 98
  
  Pages: 148-153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591566
[Journal Article] CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cell in gastric cancer.2008
- Author(s)
  Mizukami Y, Kono K, Kawaguchi Y, Akaike H, Kamimura K, Sugai H, Fujii H
- Journal Title
  
  Int J Cancer 122(10)
  
  Pages: 2286-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790947
[Journal Article] Targeting EGFR and HER2 with Cetuximab and Trastuzumab-mediated immunotherapy in esophageal squamous cell carcinoma.2007
- Author(s)
  Yoshihiko Kawaguchi, Koji Kono, et. al.
- Journal Title
  
  British Journal of Cancer 97
  
  Pages: 491-501
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591459
[Journal Article] Cetuximab induce antibody-dependent cellular cytotoxicity against EGFR-expressing esophageal squamous cell carcinoma.2007
- Author(s)
  Yoshihiko Kawaguchi, Koji Kono, Hidemitsu Sugai, et. al.
- Journal Title
  
  International Journal of Cancer. 120
  
  Pages: 781-787
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591459
[Journal Article] Targeting EGFR and HER2 with Cetuximab- and Trastuzumab-mediated immunotherapy in esophageal squamous cell carcinoma.2007
- Author(s)
  Yoshihiko Kawaguchi
- Journal Title
  
  British Journal of Cancer 97
  
  Pages: 494-501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591459
[Journal Article] Cetuximab induce antibody-dependent cellular cytotoxicity against EGFR-expressing esophageal squamous cell carcinoma.2007
- Author(s)
  Kawaguchi Y, Kono K, Mimura K, Sugai H, Akaike H, Fujii H
- Journal Title
  
  International Journal of Cancer. 120
  
  Pages: 781-787
- Data Source
  KAKENHI-PROJECT-18591459
[Journal Article] Targeting EGFR and HER2 with Cetuximab and Trastuzumab-mediated immunotherapy in esophageal squamous cell carcinoma2007
- Author(s)
  Yoshihiko, Kawaguchi, Koji, Kono, et. al.
- Journal Title
  
  British journal of Cancer 97
  
  Pages: 494-501
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591459
[Journal Article] Cetuximab induce antibody-dependent cellular cytotoxicity against EGFR-expressing esophageal squamous cell carcinoma.2007
- Author(s)
  Yoshihiko Kawaguchi
- Journal Title
  
  International Journal of Cancer. 120
  
  Pages: 781-787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591459
[Presentation] 胃癌細胞に対する可溶性Podoplaninの作用機序の解析2022
- Author(s)
  滝口光一、庄田勝俊、古屋信二、仲山孝、高橋和徳、山本淳史、齊藤亮、白石謙介、赤池英憲、細村直弘、河口賀彦、雨宮秀武、川井田博充、河野寛、大辻英吾、市川大輔
- Organizer
  JDDW2022
- Data Source
  KAKENHI-PROJECT-20K09031
[Presentation] スキルス胃癌の制圧に向けての進歩　血小板に着目した胃癌術後腹膜播種再発　新規治療標的の開発と臨床応用を目指して2021
- Author(s)
  齊藤亮, 庄田勝俊, 古屋信二, 仲山孝, 赤池英憲, 河口賀彦, 雨宮秀武, 川井田博充, 河野寛, 市川大輔
- Organizer
  日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-20K09031
[Presentation] 胃癌進展における血小板の役割2021
- Author(s)
  齊藤亮, 庄田勝俊, 丸山傑, 赤池英憲, 河口賀彦, 山本淳史, 滝口光一, 古屋信二, 細村直弘, 雨宮秀武, 川井田博充, 須藤誠, 井上慎吾, 河野寛, 市川大輔
- Organizer
  日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K09031
[Presentation] 胃癌進展における血小板の役割2020
- Author(s)
  齊藤亮、庄田勝俊、丸山傑、山本淳史、滝口光一、古屋信二、赤池英憲、細村直弘、河口賀彦、雨宮秀武、川井田博充、須藤誠、井上慎吾、河野寛、市川大輔
- Organizer
  第31回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-20K09031
[Presentation] 胃癌における CY1 PO 症例の検討2012
- Author(s)
  河口賀彦
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  幕張メッセ(千葉県)
- Year and Date
  2012-04-12
- Data Source
  KAKENHI-PROJECT-22591452
[Presentation] 進行再発食道癌に対するDocetaxel/CDDP/5-FU(DCF)療法の検討2011
- Author(s)
  河口賀彦
- Organizer
  第65回日本食道学会学術集会
- Place of Presentation
  仙台国際センター(宮城県)
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-22591452
[Presentation] 食道扁平上皮癌に対する癌ワクチン療法の開発2010
- Author(s)
  河野浩二, 水上佳樹, 河口賀彦, 三村耕作, 渡邉光章, 丸山孝教, 井澤伸一郎, 柴修吾, 藤井秀樹
- Organizer
  第47回日本癌治療学会学術集会
- Place of Presentation
  神奈川
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-20591566
[Presentation] 新規Oncoantigenを用いた食道扁平上皮癌に対する癌ワクチン療法の臨床試験2010
- Author(s)
  河野浩二, 水上佳樹, 河口賀彦, 三村耕作, 柴修吾, 井澤伸一郎, 渡邉光章, 丸山孝教, 中村祐輔, 藤井秀樹
- Organizer
  第18回日本消化器関連学会週間
- Place of Presentation
  神奈川
- Year and Date
  2010-10-12
- Data Source
  KAKENHI-PROJECT-20591566
[Presentation] 新規Oncoantigenを用いた食道扁平上皮癌に対する。癌ワクチン療法の開発2010
- Author(s)
  河野浩二, 水上佳樹, 河口賀彦, 三村耕作, 柴修吾, 渡邉光章, 丸山孝教, 井澤伸一郎, 藤井秀樹, 中村祐輔
- Organizer
  第110回日本外科学会定期学術集会
- Place of Presentation
  愛知
- Year and Date
  2010-04-08
- Data Source
  KAKENHI-PROJECT-20591566
[Presentation] Vaccination with multiple peptides derived from novel cancer-testis antigens against advanced cancer2010
- Author(s)
  河野浩二, 水上佳樹, 三村耕作, 河口賀彦, 藤井秀樹, 中村祐輔
- Organizer
  69th Annual Meeting of the Japanese
- Place of Presentation
  Osaka
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20591566
[Presentation] 食道扁平上皮癌に対する癌ワクチン療法と宿主免疫応答2009
- Author(s)
  河野浩二, 水上佳樹, 河口賀彦, 渡邉光章, 丸山孝教, 平井優, 醍醐弥太郎, 中村祐輔, 藤井秀樹
- Organizer
  第109回日本外科学会定期学術集会
- Place of Presentation
  福岡
- Year and Date
  2009-04-02
- Data Source
  KAKENHI-PROJECT-20591566
[Presentation] 食道扁平上皮癌に対する癌ワクチン療法2009
- Author(s)
  河野浩二, 水上佳樹, 醍醐弥太郎, 三村耕作, 河口賀彦, 藤井秀樹, 吉田浩二, 中村祐輔
- Organizer
  第63回日本食道学会学術集会
- Place of Presentation
  神奈川
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20591566
[Presentation] 食道扁平上皮癌に対する癌ワクチン療法の開発2009
- Author(s)
  河野浩二, 水上佳樹, 河口賀彦, 三村耕作, 渡邉光章, 丸山孝教, 藤井秀樹, 醍醐弥太郎, 中村祐輔
- Organizer
  第63回日本食道学会学術集会
- Place of Presentation
  神奈川
- Year and Date
  2009-06-25
- Data Source
  KAKENHI-PROJECT-20591566
[Presentation] 食道扁平上皮癌に対する新規癌拒絶抗原を用いた癌ワクチン療法の開発2009
- Author(s)
  河野浩二, 水上佳樹, 河口言彦, 三村耕作, 渡邉光章, 丸山孝教, 井澤伸一郎, 藤井秀樹, 中村祐輔
- Organizer
  第64回日本消化器外科学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-07-16
- Data Source
  KAKENHI-PROJECT-20591566
[Presentation] 食道癌のTrastuzumab耐性のメカニズムに関する検討2008
- Author(s)
  河口賀彦
- Organizer
  第29回癌免疫外科研究会
- Place of Presentation
  ホテル日航東京
- Year and Date
  2008-06-19
- Data Source
  KAKENHI-PROJECT-20790947
[Presentation] 食道癌のTrastuzumab耐性のメカニズムに関する検討2008
- Author(s)
  河口賀彦, 河野浩二, 水上佳樹, 三村耕作, 渡邉光章, 丸山孝教, 藤井秀樹
- Organizer
  第29回癌免疫外科研究会
- Place of Presentation
  東京
- Year and Date
  2008-06-19
- Data Source
  KAKENHI-PROJECT-20790947
[Presentation] 新規CTA抗原を用いた食道癌に対するマルチエピドープ癌ワクチン療法第1相試験2008
- Author(s)
  河野浩二, 水上佳樹, 醍醐弥太郎, 角田卓也, 河口賀彦, 中村祐輔, 藤井秀樹
- Organizer
  第67回日本癌学会学術総会
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20591566

1. KONO Koji (40283204)

# of Collaborated Projects: 3 results

# of Collaborated Products: 33 results
2. 赤池英憲 (00402032)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. NAKAMURA Yusuke (70217909)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
4. MIZUKAMI Yoshiki (70530111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. SUGAI Hidemitsu (10345712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. Ichikawa Daisuke (20347446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
7. 古屋信二 (80622381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. 庄田勝俊 (70783421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

KAWAGUCHI Yoshihiko 河口 賀彦

河口 賀彦 カワグチ ヨシヒコ

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism of hematopoietic cell-mediated cancer progression in gastrointestinal cancer and development of new treatment methods

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the anti-HER3 antibody therapy for esophageal squamous cell carcinoma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Distribution of Th17 cells related to regulatory T cells withintumor-microenvironment in cancer-bearing hosts.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of escape from trastuzumab-mediated ADCC in esophageal squamous cell carcinoma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Cancer Vaccination with Multiple Peptides derived from Novel Cancer-Testis Antigens against esophageal cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of escape from trastuzumab-mediated ADCC in esophageal squamous cell carcinoma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cancer vaccination therapy for gastric and esophageal cancer as an adjuvant setting after resection

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Soluble podoplanin as a biomarker in diffuse type gastric cancer.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Platelets enhance malignant behaviours of gastric cancer cells via direct contacts.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Exposure to Blood Components and Inflammation Contribute to Pancreatic Cancer Progression2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lapatinib inhibits receptor phosphorylation and cell growth and enhances antibody dependent cellular cytotoxicity (ADCC) of EGFR and HER2 over-expressing esophageal cancer cell lines.2011

Author(s)

Journal Title

Data Source

[Journal Article] Lapatinib inhibits receptorphosphorylation and cell growth andenhances antibody dependent cellularcytotoxicity(ADCC) of EGFR and HER2over-expressing esophageal cancercell lines2011

Author(s)

Journal Title

Data Source

[Journal Article] Immunonutritional diet modulatesnatural killer cell activation andTh17 cell distribution in patientswith gastric and esophageal cancer2011

Author(s)

Journal Title

Data Source

[Journal Article] Immunonutritional diet modulates NK cell activation and Th17 cell distribution in patients with gastric and esophageal cancer.2011

Author(s)

Journal Title

Data Source

[Journal Article] Lapatinib inhibits receptor phosphorylation and cell growth and enhances antibody dependent cellular cytotoxicity(ADCC) of EGFR and HER2 over-expressing esophageal cancer cell lines2011

Author(s)

KAWAGUCHI Yoshihiko 河口賀彦

河口賀彦カワグチヨシヒコ