Yamashita Kouhei 山下浩平

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YAMASHITA Kouhei 山下浩平

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Researcher Number	80402858
Affiliation (Current)	2025: 京都大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2023: 京都大学, 医学研究科, 准教授 2015: 京都大学, 医学(系)研究科(研究院), 准教授 2011 – 2013: 京都大学, 医学(系)研究科(研究院), 講師 2011 – 2012: 京都大学, 医学研究科, 講師 2010: Kyoto University, 大学院・医学研究科, 助教 2007 – 2010: Kyoto University, Medicine, Assistant Professor 2006: 京都大学, 医学研究科, 助手
Review Section/Research Field	Principal Investigator Infectious disease medicine / Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 54010:Hematology and medical oncology-related / Hematology Except Principal Investigator Anesthesiology/Resuscitation studies
Keywords	Principal Investigator 好中球細胞外トラップ / 好中球 / 血管炎 / 自然免疫 / 川崎病 / 形質細胞様樹状細胞 / スフィンゴ脂質 / IgG4関連疾患 / 一重項酸素 / 殺菌 … More / 免疫寛容 / 同種移植 / 慢性移植片対宿主病 / Ⅰ型インターフェロン / 慢性GVHD / 血管障害 / シトルリン化ヒストン / PAD阻害薬 / 炎症性疾患 / 移植片対宿主病 / IL-33 / 1型インターフェロン / PAD4阻害剤 / PAD阻害剤 / 流産 / スフィンゴシンキナーゼ / 不育症 / 自己免疫性膵炎 / 慢性肉芽腫症 / 活性酸素 / 微小血管障害 / 同種造血細胞移植 / 血管内皮細胞障害 / 細胞外トラップ / 心血管障害 / 高尿酸血症 / 造血幹細胞移植 / 血栓性微小血管障害 / NADPH oxidase / アミノ酸 / 免疫グロブリン / オゾン … More Except Principal Investigator 一重項酸素 / 活性酸素 / スーパーオキシド / ヒト好中球 / siRNA / プテリン化合物 / エダラボン / グルタミン酸 / 神経細胞 / 細胞死 / Interleukin-8 / Human umbilical endothelial cells / Reactive oxygen species / Real time PCR / Short interfering RNA / RNA interference / Myeronperoxidaes / Neutreopils / 化学発光 / ミエロペルオキシダーゼ / 蛍光試薬DCFH / フローサイトメーター / RNA干渉 / インターロイキン-8 / ヒト臍帯静脈内皮細胞 / インターロイキン-8(IL-8) / ヒト臍帯静脈内皮細胞(HUVECs) / リアルタイムPCR / 短鎖干渉用RNA(siRNA) / RNA干渉(RNAi) / ミエロペルオキシダーゼ(MPO) / ラマン分光法 / アジ化ナトリウム / 放射線障害 / 皮膚細胞 / 特異的消去剤 / ELISA / ゲル電気泳動 / リアルタイムPC / MTTアッセイ / 遺伝子導入 / 組織因子 / 播種性血管内凝固症候 / NADPHオキシダーゼ-1 / インターロイキン8 / LPS / 血管内皮細胞 / 組織傷害 / 白血病細胞 / 新規一重項酸素消去剤 / オートファジー / 神経様細胞 / NETs / 好中球 / 細胞活性 / NETosis / アポトーシス / 自己貪食型 / 壊死型 Less

自然免疫に着目した、川崎病の病態解明および新規治療法の開発Principal Investigator
- Principal Investigator
  
  山下浩平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kyoto University
The role of neutrophil extracellular traps in the pathogenesis of chronic GVHDPrincipal Investigator
- Principal Investigator
  
  Yamashita Kouhei
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
The role of neutrophil extracellular traps in the pathogenesis of immunological, inflammatory, or thrombotic diseasesPrincipal Investigator
- Principal Investigator
  
  Yamashita Kouhei
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
Analysis of a mechanism of neutrophil extracellular trap (NET) fromation and a role of NETs in infectious and inflammatory diseases.Principal Investigator
- Principal Investigator
  
  YAMASHITA KOUHEI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Kyoto University
Development of the novel compound which specifically scavenges singlet oxygen extra- and intracellularly.
- Principal Investigator
  
  ARAI Toshiyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kyoto University
Determination of the active reactive oxygen species that generated in cells during ischemia-reperfusion and selection of its specific scavenger.
- Principal Investigator
  
  ARAI Toshiyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kyoto University
RNA干渉を用いた血管内皮細胞インターロイキン発現抑制による敗血症組織傷害の緩和
- Principal Investigator
  
  荒井俊之
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kyoto University
Study of the mechanism of ozone production and application for enhancement of bactericidal activity in human neutrophilsPrincipal Investigator
- Principal Investigator
  
  YAMASHITA Kouhei
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Kyoto University
Protection against ischemia-reperfusion injury using a short interfering RNA that inhibits the activity of myeloperoxidase
- Principal Investigator
  
  ARAI Toshiyuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kyoto University

All 2020 2017 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Exaggerated neutrophil extracellular trap formation in Kawasaki disease: A key phenomenon behind the outbreak in western countries?2020
- Author(s)
  Yamashita K, Takaori-Kondo A, Mizugishi K.
- Journal Title
  
  Ann Rheum Dis
  
  Volume: Aug 21 Issue: 9 Pages: 2020-218593
- DOI
  10.1136/annrheumdis-2020-218593
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08353
[Journal Article] Neutrophil extracellular traps are critical for pregnancy loss in sphingosine kinase-deficient mice on 129Sv/C57BL/6 background.2017
- Author(s)
  Mizugishi K and Yamashita K.
- Journal Title
  
  FASEB J.
  
  Volume: 31 Issue: 12 Pages: 5577-5591
- DOI
  10.1096/fj.201700399rr
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09499, KAKENHI-PROJECT-15K09711
[Journal Article] Chronic Fibro-Inflammatory Responses in Autoimmune Pancreatitis Depend on IFN-α and IL-33 Produced by Plasmacytoid Dendritic Cells.2017
- Author(s)
  Watanabe T, Yamashita K, Arai Y, Minaga K, Kamata K, Nagai T, Komeda Y, Takenaka M, Hagiwara S, Ida H, Sakurai T, Nishida N, Strober W, Kudo M.
- Journal Title
  
  J Immunol
  
  Volume: 印刷中 Issue: 10 Pages: 3886-3896
- DOI
  10.4049/jimmunol.1700060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460979, KAKENHI-PROJECT-15K09499, KAKENHI-PROJECT-17K09396
[Journal Article] Phagocytosis by human monocytes is required for the secretion of presepsin.2015
- Author(s)
  Arai Y, Mizugishi K, Nonomura K, Naito K, Takaori-Kondo A, Yamashita K.
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 21 Issue: 8 Pages: 564-569
- DOI
  10.1016/j.jiac.2015.04.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09499, KAKENHI-PROJECT-15K09711, KAKENHI-PROJECT-24591600
[Journal Article] Enhancement of neutrophil autophagy by an IVIG preparation against　multi-drug-resistant bacteria as well as drug sensitive strains.2015
- Author(s)
  Itoh H, Matsuo H, Kitamura N, Yamamoto S, Higuchi T, Takematsu H, Kamikubo Y, Kondo T, Yamashita K, Sasada M, Takaori-Kondo A, Adachi S.
- Journal Title
  
  Journal of Leukocyte Biology
  
  Volume: 98 Issue: 1 Pages: 107-117
- DOI
  10.1189/jlb.4a0813-422rrr
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09499, KAKENHI-PROJECT-25461420, KAKENHI-PROJECT-26670484
[Journal Article] 自己免疫性膵炎の診断について　診断基準の変遷と診断の現状2015
- Author(s)
  内田一茂, 岡崎和一
- Journal Title
  
  日本臨床免疫学会雑誌
  
  Volume: 38 Issue: 7 Pages: 127-134
- DOI
  10.4049/jimmunol.1500971
- NAID
  130005089220
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09052, KAKENHI-PROJECT-15K09499, KAKENHI-PROJECT-15K09501, KAKENHI-PROJECT-15K09711, KAKENHI-PROJECT-26460979, KAKENHI-PROJECT-15K15370, KAKENHI-PROJECT-24591600, KAKENHI-PROJECT-25293172
[Journal Article] 好中球の細胞外殺菌機構(NETs)-感染防御における役割と自己免疫・炎症病態への関与-2014
- Author(s)
  新井康之,山下浩平
- Journal Title
  
  炎症と免疫
  
  Volume: 22 Pages: 122-34
- Data Source
  KAKENHI-PROJECT-23591474
[Journal Article] Uric acid induces NADPH oxidase-independent neutrophil extracellular trap formation2014
- Author(s)
  Arai Y, Nishinaka Y, Arai T, Morita M, Mizugishi K, Adachi S, Takaori-Kondo A, Watanabe T, Yamashita K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 443 Pages: 556-61
- NAID
  40021104154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474
[Journal Article] Uric acid induces NADPH oxidase-independent neutrophil extracellular trap formation.2014
- Author(s)
  Arai Y, Nishinaka Y, Arai T, Morita M, Mizugishi K, Adachi S, Takaori-Kondo A, Watanabe T, Yamashita K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 443 Issue: 2 Pages: 556-561
- DOI
  10.1016/j.bbrc.2013.12.007
- NAID
  40021104154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474, KAKENHI-PROJECT-24591600
[Journal Article] CKIP-1 Is an Intrinsic Negative Regulator of T-Cell Activation through an Interaction with CARMA1.2014
- Author(s)
  Sakamoto T, Kobayashi M, Tada K, Shinohara M, Io K, Nagata K, Iwai F, Takiuchi Y, Arai Y, Yamashita K, Shindo K, Kadowaki N, Koyanagi Y, Takaori-Kondo A
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 1 Pages: 1-11
- DOI
  10.1371/journal.pone.0085762
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390110, KAKENHI-PROJECT-23591383, KAKENHI-PROJECT-23591474, KAKENHI-PLANNED-24115004, KAKENHI-PLANNED-24115008
[Journal Article] Toll-like receptor activation in basophils contributes to the development of IgG4-related disease.2013
- Author(s)
  Watanabe T, Yamashita K, Sakurai T, et al
- Journal Title
  
  J Gastroenterol
  
  Volume: 48 Issue: 2 Pages: 247-253
- DOI
  10.1007/s00535-012-0626-8
- NAID
  10031156310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590998, KAKENHI-PROJECT-23591474, KAKENHI-PROJECT-24591020
[Journal Article] Enhanced generation of reactive oxygen species by interferon-may have contributed to successful treatment of invasive pulmonary aspergillosis in a patient with chronic granulomatous disease2013
- Author(s)
  Yamashita K, Miyoshi T, Arai Y, Mizugishi K, Takaori-Kondo A, Ueyama T
- Journal Title
  
  Int J Hematol
  
  Volume: 97 Pages: 505-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474
[Journal Article] The implication of myelodysplastic syndrome-associated chromosomal abnormalities in the development of graft-versus-host disease2013
- Author(s)
  Arai Y, Yamashita K, Mizugishi K, Takaori-Kondo A, Chiba T, Watanabe T
- Journal Title
  
  Eur J Haematol
  
  Volume: 90 Pages: 525-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474
[Journal Article] Toll-like receptor activation in basophils contributes to the development of IgG4-related disease2013
- Author(s)
  Watanabe T, Yamashita K, Sakurai T, Kudo M, Shiokawa M, Uza N, Kodama Y, Uchida K, Okazaki K, Chiba T
- Journal Title
  
  J Gastroenterol
  
  Volume: 48 Pages: 247-53
- NAID
  10031156310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474
[Journal Article] Familial Mediterranean fever mutations in a patient with recurrent episodes of acute respiratory distress syndrome.2013
- Author(s)
  Arai Y, Yamashita K, Mizugishi K, Watanabe T, Kondo T, Kitano T, Kawabata H, Kadowaki N, Takaori-Kondo A.
- Journal Title
  
  Clin Immunol
  
  Volume: 147 Issue: 1 Pages: 58-60
- DOI
  10.1016/j.clim.2013.02.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474, KAKENHI-PROJECT-24591600
[Journal Article] Clinical value of (11)C-methionine PET/CT in patients with plasma cell malignancy: comparison with (18)F-FDG PET/CT2013
- Author(s)
  Nakamoto Y, et al
- Journal Title
  
  Eur J Nucl Med Mol Imaging
  
  Volume: Vol.40、No.5 Issue: 5 Pages: 708-715
- DOI
  10.1007/s00259-012-2333-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591329, KAKENHI-PROJECT-23591474
[Journal Article] Serum neutrophil extracellular traps levels predict thrombotic microangiopathy after allogeneic stem cell transplantation.2013
- Author(s)
  Arai Y, Yamashita K, Mizugishi K, Watanabe T, Sakamoto S, Kitano T, Kondo T, Kawabata H, Kadowaki N, Takaori-Kondo A.
- Journal Title
  
  Biol Blood Marrow Transpl
  
  Volume: 19 Issue: 12 Pages: 1683-1689
- DOI
  10.1016/j.bbmt.2013.09.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474, KAKENHI-PROJECT-24591600
[Journal Article] The implication of myelodysplastic syndrome-associated chromosomal abnormalities in the development of graft-versus-host disease.2013
- Author(s)
  Arai Y, Yamashita K, Mizugishi K, Takaori-Kondo A, Chiba T, Watanabe T.
- Journal Title
  
  Eur J Haematol
  
  Volume: 90 Issue: 6 Pages: 525-530
- DOI
  10.1111/ejh.12100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591474, KAKENHI-PROJECT-24229005, KAKENHI-PROJECT-24591600
[Journal Article] Differing impacts of pretransplant serum ferritin and c-reactive protein levels on the incidence of chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation2013
- Author(s)
  Sakamoto S, Kawabata H, Kanda J, Uchiyama T, Mizumoto C, Kondo T, Yamashita K, Ichinohe T, Ishikawa T, Kadowaki N, Takaori-Kondo A
- Journal Title
  
  Int J Hematol
  
  Volume: 97 Issue: 1 Pages: 109-116
- DOI
  10.1007/s12185-012-1229-0
- NAID
  10031144642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591033, KAKENHI-PROJECT-23591474
[Journal Article] Enhanced generation of reactive oxygen species by interferon-gamma may have contributed to successful treatment of invasive pulmonary aspergillosis in a patient with chronic granulomatous disease.2013
- Author(s)
  Yamashita K, Miyoshi T, Arai Y, Mizugishi K, Takaori-Kondo A, Ueyama T.
- Journal Title
  
  Int J Hematol
  
  Volume: 97 Issue: 4 Pages: 505-510
- DOI
  10.1007/s12185-013-1315-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474, KAKENHI-PROJECT-24591600
[Journal Article] Serum neutrophil extracellular traps levels predict thrombotic microangiopathy after allogeneic stem cell transplantation2013
- Author(s)
  Arai Y, Yamashita K, Mizugishi K, Watanabe T, Sakamoto S, Kitano T, Kondo T, Kawabata H, Kadowaki N, Takaori-Kondo A
- Journal Title
  
  Biol Blood Marrow Transpl
  
  Volume: 19 Pages: 1683-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474
[Journal Article] Familial Mediterranean fever mutations in a patient with recurrent episodes of acute respiratory distress syndrome2013
- Author(s)
  Arai Y, Yamashita K, Mizugishi K, Watanabe T, Kondo T, Kitano T, Kawabata H, Kadowaki N, Takaori-Kondo A
- Journal Title
  
  Clin Immunol
  
  Volume: 147 Pages: 58-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474
[Journal Article] Activation of toll-like receptors and NOD-like receptors in involved in enhanced IgG4 responses in autoimmune pancreatitis2012
- Author(s)
  Watanabe T, Yamashita K, Fujikawa S, Sakurai T, Kudo M, Shiokawa M, Kodama Y, Uchida K, Okazaki K, Chiba T
- Journal Title
  
  Arthritis Rheum
  
  Volume: 64 Pages: 914-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474
[Journal Article] Involvement of activation of toll-like receptors and nucleotide-binding oligomerization domain-like receptors in enhanced IgG4 responses in autoimmune pancreatitis.2012
- Author(s)
  Watanabe T, Yamashita K, Fujikawa S, Sakurai T, Kudo M, Shiokawa M, Kodama Y, Uchida K, Okazaki K, Chiba T.
- Journal Title
  
  Arthritis Rheum
  
  Volume: 64 Pages: 914-924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474
[Journal Article] Singlet oxygen is essential for neutrophil extracellular trap formation2011
- Author(s)
  Nishinaka Y, Arai T, Adachi S, Takaori-Kondo A, Yamashita K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 413 Pages: 75-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474
[Journal Article] Singlet oxygen is essential for neutrophil extracellular trap formation2011
- Author(s)
  Yoko Nishinaka
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 413 Issue: 1 Pages: 75-79
- DOI
  10.1016/j.bbrc.2011.08.052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03388, KAKENHI-PROJECT-21390433, KAKENHI-PROJECT-23659740
[Journal Article] Singlet oxygen is essential for neutrophil extracellular trap formation.2011
- Author(s)
  Nishinaka Y, Arai T, Adachi S, Takaori-Kondo A, Yamashita K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 413 Pages: 75-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591474
[Journal Article] 造血器疾患・続発性免疫不全症における低ガンマグロブリン血症2010
- Author(s)
  山下浩平
- Journal Title
  
  血液フロンティア 20
  
  Pages: 1999-2006
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] Edaravone directly reacts with singlet oxygen and protects cells from attack.2010
- Author(s)
  Nishinaka Y, Mori H, Endo N, Miyoshi T, Yamashita K, Adachi S, Arai T
- Journal Title
  
  Life Sci 86
  
  Pages: 808-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] 広範囲血液・尿化学検査第7版,免疫学的検査(3)-その数値をどう読むか-.2010
- Author(s)
  山下浩平, 三好隆史
- Journal Title
  
  好中球機能検査(貪食能、殺菌能、遊走能、活性酸素産生能、接着分子発現能)(日本臨床社)
  
  Pages: 877-80
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] NB4 cells treated with all-trans retinoic acid generate toxic reactive oxygen species that cause endothelial hyperpermeability.2010
- Author(s)
  Miyoshi T, Arai T, Yamashita K, Sasada M, Uchiyama T.
- Journal Title
  
  Leuk Res 34
  
  Pages: 373-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] 学会印象記-第84回日本感染症学会総会-.2010
- Author(s)
  山下浩平
- Journal Title
  
  臨床と微生物 37
  
  Pages: 407-407
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] Substituient effects of pterin derivatives on singlet oxygen scavenging activity2010
- Author(s)
  Mori H, Nishinaka Y, Nonogawa M, Sommani P, Makino K, Yamashita K
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 33 Pages: 905-908
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390433
[Journal Article] Edaravone directly reacts with singlet oxygen and protects cells from attack.2010
- Author(s)
  Nishinaka Y, Mori H, Yamashita K, et al.
- Journal Title
  
  Life Sciences
  
  Volume: 86 Pages: 803-813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] Edaravone directly reacts with singlet oxygen and protects cells from attack2010
- Author(s)
  Nishinaka Y, Mori H, Endo N, Miyoshi T, Yamashita K, Adachi S
- Journal Title
  
  Life Sci
  
  Volume: 86 Issue: 21-22 Pages: 808-813
- DOI
  10.1016/j.lfs.2010.03.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390433
[Journal Article] The rapid induction of HLA-E is essential for the survival of antigen-activated naive CD4 T cells from attack by NK cells.2010
- Author(s)
  Takao S, Ishikawa T, Yamashita K, Uchiyama T.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 185 Pages: 6031-6040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] Substituent effects of pterin derivatives on singlet oxygen scavenging activity.2010
- Author(s)
  Mori H, Nishinaka Y, Nonogawa M, Sommani P, Makino K, Yamashita K, Arai T
- Journal Title
  
  Biol Pharm Bull 33
  
  Pages: 905-8
- NAID
  130000248057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] Uchiyama T : NB4 cells treated with all-trans retinoic acid generate toxic reactive oxygen species that cause endothelial hyper permeability2010
- Author(s)
  Miyoshi T, Arai T, Yamashita K, Sasada M
- Journal Title
  
  Leukemia Res
  
  Volume: 34 Issue: 3 Pages: 373-378
- DOI
  10.1016/j.leukres.2009.05.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390433
[Journal Article] The role of endothelial interleukin-8/NADPH oxidase 1 axis in sepsis2010
- Author(s)
  Miyoshi T, Yamashita K, et al.
- Journal Title
  
  Immunology
  
  Volume: 131 Pages: 331-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] NB4 cells treated with all-trans retinoic acid generate toxic reactive oxygen species that cause endothelial hyperpermeability.2010
- Author(s)
  Miyoshi T, Arai T, Yamashita K, et al.
- Journal Title
  
  Leukemia Research 34
  
  Pages: 373-378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] The role of endothelial Interleukin-8/NADPH oxidasel axis in sepsis.2010
- Author(s)
  Miyoshi T, Yamashita K, Arai T, Yamamoto K, Mizugishi K, Uchiyama T
- Journal Title
  
  Immunology 131
  
  Pages: 331-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] The radical scavenger edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one) reacts with a pterin derivative and produces a cytotoxic substance that induces intracellular reactive oxygen species generation and cell death.2008
- Author(s)
  Arai T, Nonogawa M, Makino K, Endo N, Mori H, Miyoshi T, Yamashita K, Sasada M, Kakuyama M, Fukuda K
- Journal Title
  
  J Pharmcol Exp Ther 324
  
  Pages: 529-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] Ozone production by amino acids contributes to killing of bacteria.2008
- Author(s)
  Yamashita K, Miyoshi T, Arai T, Endo N, Itoh H, Makino K, Mizugishi K, Uchiyama T, Sasada M
- Journal Title
  
  Proc Natl Acad Sci USA 105
  
  Pages: 16912-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] Effects of iniectable propofol emulsion on singlet oxygen released from activated human neutrophils and that cheiically generated.2008
- Author(s)
  Senda C, Nishinaka Y, Yamashita K, et al.
- Journal Title
  
  J Pharmacol Sci 107
  
  Pages: 460-464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] Anticancer photodynamic and non-photodynamic effects of pterin derivatives on a pancreatic cancer cell line2008
- Author(s)
  Miyoshi, T., Arai, T., Nonogawa, M., Makino, K., Mori, H., Yamashita, K., Sasada, M., Uchiyama, T
- Journal Title
  
  J Pharmacol Sci (in press)
- NAID
  10024321141
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390428
[Journal Article] a-Phenyl-N-tert-butyl nitrone has scavenging activity against singlet oxygen (1O2) and attenuates 1^O_2-induced neuronal cell death.2008
- Author(s)
  Kawai A, Nishinaka Y, Arai T, Hirota K, Mori H, Endo N, Miyoshi T, Yamashita K, Sasada M
- Journal Title
  
  J Pharmacol Sci 108
  
  Pages: 545-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] The radical scavenger edaravone (3-methyl-l-phenyl-2-pyrazolin-5-one) reacts with a pterin derivative and produces a cytotoxic substance that induces intracellular ROS generation and cell death2008
- Author(s)
  Arai, T., Nonogawa, M., Makino, K., Endo, N., Mori, H., Miyoshi, T., Yamashita, K., Sasada, M., Kakuyama, M., Fukuda, K
- Journal Title
  
  J Pharmacol Exp Ther 324
  
  Pages: 529-538
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390428
[Journal Article] Effects of injectable propofol emulsion on singlet oxygen released from activated human neutrophils and that chemically generated.2008
- Author(s)
  Senda C, Nishinaka Y, Arai T, Segawa H, Mori H, Nonogawa M, Endo N, Miyoshi T, Yamashita K, Sasada M
- Journal Title
  
  J Pharmacol Sci 107
  
  Pages: 460-4
- NAID
  10024322116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] Anticancer photodynamic and non-photodynamic effects of pterin derivatives on a pancreatic cancer cell line.2008
- Author(s)
  Miyoshi T, Arai T, Nonogawa M, Makino K, Mori H, Yamashita K, Sasada M
- Journal Title
  
  J Pharmacol Sci 107
  
  Pages: 221-5
- NAID
  10024321141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] 疾患と検査値の推移-家族性地中海熱-.2008
- Author(s)
  山下浩平, 三好隆史
- Journal Title
  
  検査と技術 36
  
  Pages: 29-34
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] Familial Mediterranean fever gene as a possible modifier of Sweet syndrome with chronic myelogenous leukemia.2008
- Author(s)
  Miyoshi T, Yamashita K, Ohno T, et al.
- Journal Title
  
  Acta Haeraatol 120
  
  Pages: 57-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] Ozone production by amino aicds contributes to killing of bacteria.2008
- Author(s)
  Yamashita K, Miyoshi T, Arai T, et al.
- Journal Title
  
  Proc Natl Acad Sci USA. 105
  
  Pages: 16912-16917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591200
[Journal Article] Inhibitory effects of 6-formylpterin on HIF-la protein accumulation2007
- Author(s)
  Sommani, P., Yamashita, K., Miyoshi, T., Tsunemine, H., Kodaki, T., Mori, H., Hirota, K., Arai, T., Sasada, M., Makino, K
- Journal Title
  
  Biol Pharm Bull 30
  
  Pages: 2181-2184
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390428
[Journal Article] Effects of edaravone on singlet oxygen released from activated human neutrophils.2007
- Author(s)
  Sommani P, Arai T, Yamashita K, et al.
- Journal Title
  
  J Pharmacol Sci 103
  
  Pages: 117-120
- NAID
  10024312242
- Data Source
  KAKENHI-PROJECT-18390428
[Journal Article] Effects of edaravone on singlet oxygen released from activated human neutrophils2007
- Author(s)
  Sommani, P., Arai, T., Yamashita, K., Miyoshi, T., Mori, H., Sasada, M., Makino, K
- Journal Title
  
  J Pharmacol Sci 103
  
  Pages: 117-120
- NAID
  10024312242
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390428
[Journal Article] Effects of edaravone on singlet oxygen released from activated human neutrophils.2007
- Author(s)
  Sommani P, Arai T, Yamashita K, et. al.
- Journal Title
  
  J Pharmacol Sci 1003
  
  Pages: 117-120
- NAID
  10024312242
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390428
[Journal Article] Inhibitory effects of 6-formylpterin on HIF-la protein accumulation.2007
- Author(s)
  Sommari P, Yamashita K, Miyoshi T, et. al.
- Journal Title
  
  Biol Pharm Bull 30
  
  Pages: 2181-2184
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390428
[Presentation] Uric Acid Induces NADPH Oxidase-Independent Neutrophil Extracellular Trap Formation2013
- Author(s)
  Arai Y, Nishinaka Y, Arai T, Mizugishi K, Adachi S, Takaori-Kondo A, Yamashita K
- Organizer
  55th Annual Meeting of the American Society of Hematology
- Place of Presentation
  New Orleans, USA
- Year and Date
  2013-12-10
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] Plasmacytoid dendritic cells activated by neutrophil extracellular traps contribute to the pathogenesis of IgG4-related disease2013
- Author(s)
  Arai Y, Yamashita K, Mizugishi K, Takaori-Kondo A
- Organizer
  Annual European Congress of Rheumatology EULAR 2013
- Place of Presentation
  Madrid, Spain
- Year and Date
  2013-06-13
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] Serum Neutrophil Extracellular Traps (NETs) Are a Potential Predictive Marker for Thrombotic Microangiopathy (TMA) After Allogeneic Stem Cell Transplantation.2012
- Author(s)
  Arai Y, Sakamoto S, Yamashita K, Mizugishi K, Kitano T, Kondo T, Kawabata H, Kadowaki N, Takaori-Kondo A.
- Organizer
  54th Annual Meeting of the American Society of Hematology
- Place of Presentation
  米国Atlanta, Convention Center
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] 高濃度尿酸によるNADPH oxidase非依存性NETosisの誘導．2012
- Author(s)
  西中瑶子，森田真紀子，荒井俊之，山下浩平，足立壯一．
- Organizer
  第21回日本Cell Death学会学術集会
- Place of Presentation
  名古屋、名古屋大学医学部付属病院中央診療棟3階講堂
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] リツキシマブ投与後の遅発性好中球減少症に関する検討．2012
- Author(s)
  新井康之, 山下浩平, 近藤忠一, 高折晃史．
- Organizer
  第82回日本感染症学会中日本地方会学術集会．
- Place of Presentation
  福岡、アクロス福岡
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] 高濃度尿酸によるNADPH oxidase 非依存性 NETosis の誘導2012
- Author(s)
  西中瑶子、森田真紀子、山下浩平、荒井俊之、足立壮一
- Organizer
  第21回日本Cell Death学会
- Place of Presentation
  名古屋(名古屋大学)
- Data Source
  KAKENHI-PROJECT-23659740
[Presentation] A novel role of uric acid in neutrophil extracellular trap formation2012
- Author(s)
  Nishinaka Y, Arai T, Morita M, Arai Y, Mizugishi K, Adachi S, Takaori-Kondo A, Yamashita K
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] A novel role of uric acid in neutrophil extracellular trap formation.2012
- Author(s)
  Nishinaka Y, Arai T, Morita M, Arai Y, Mizugishi K, Adachi S, Takaori-Kondo A, Yamashita K.
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都、国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] A novel role of uric acid in neutrophils extracellular trap formation2012
- Author(s)
  Yoko Nishinaka, Toshiyuki Arai, Makiko Morita, Yasuyuki Arai, Kiyomi Mizugishi, Souichi Adachi, Akifumi Takaori-Kondo, Kouhei Yamashita
- Organizer
  第74回日本血液学会総会
- Place of Presentation
  京都(京都国際会議場)
- Data Source
  KAKENHI-PROJECT-23659740
[Presentation] Serum Neutrophil Extracellular Traps (NETs) Are a Potential Predictive Marker for Thrombotic Microangiopathy (TMA) After Allogeneic Stem Cell Transplantation2012
- Author(s)
  Arai Y, Sakamoto S, Yamashita K, Mizugishi K, Kitano T, Kondo T, Kawabata H, Kadowaki N, Takaori-Kondo A
- Organizer
  54th Annual Meeting of the American Society of Hematology
- Place of Presentation
  Atlanta, USA
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] 高濃度尿酸によるNADPH oxidase非依存性NETosisの誘導2012
- Author(s)
  西中瑶子,森田真紀子,荒井俊之,山下浩平,足立壯一
- Organizer
  第21回日本Cell Death学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2012-07-28
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] ARDSを繰り返し発症した，MEFV遺伝子変異を有するMDS/MPNの一例．2012
- Author(s)
  新井康之, 山下浩平, 水岸貴代美, 近藤忠一, 北野俊行, 川端浩, 高折晃史．
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都、国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] Singlet oxygen is essential for neutrophil extracellular trap formation.2011
- Author(s)
  Nishinaka Y, Morita M, Arai T, Adachi S, Takaori-Kondo A, Yamashita K.
- Organizer
  53rd ASH Annual Meeting and Exposition
- Place of Presentation
  米国San Diego, Convention Center
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] Singlet oxygen is essential for neutrophil extracellular trap formation2011
- Author(s)
  Nishinaka Y, Morita M, Arai T, Adachi S, Takaori-Kondo A, Yamashita K
- Organizer
  The 53^<rd> ASH Annual Meeting and Exposition
- Place of Presentation
  San Diego, USA
- Year and Date
  2011-12-12
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] NETosisにおける一重項酸素の役割2011
- Author(s)
  西中瑶子、森田真紀子、山下浩平、荒井俊之、足立壮一
- Organizer
  第20回日本Cell Death学会
- Place of Presentation
  東京(東京大学)
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-23659740
[Presentation] Akifumi Takaori-Kondo : Singlet oxygen is essential for neutrophil extracellular trap formation2011
- Author(s)
  Kouhei Yamashita, Yoko Nishinaka, Toshiyuki Arai, Souichi Adachi
- Organizer
  第73回日本血液学会総会
- Place of Presentation
  名古屋(名古屋国際会議場)
- Data Source
  KAKENHI-PROJECT-21390433
[Presentation] NETosisにおける一重項酸素の役割2011
- Author(s)
  西中瑶子、森田真紀子、山下浩平、荒井俊之、足立壮一
- Organizer
  第20回日本CellDeath学会
- Place of Presentation
  東京(東京大学)
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-21390433
[Presentation] Singlet oxygen is essential for neutrophil extracellular trap formation2011
- Author(s)
  Yoko Nishinaka, Makiko Morita, Toshiyuki Arai, Souichi Adachi, Akifumi Takaori-Kondo, Kouhei Yamashita
- Organizer
  第53回米国血液学会
- Place of Presentation
  San Diego (San Diego Convention Center, CA, USA)
- Year and Date
  2011-12-12
- Data Source
  KAKENHI-PROJECT-23659740
[Presentation] Singlet oxygen is essential for neutrophil extracellular trap formation2011
- Author(s)
  Kouhei Yamashita, Yoko Nishinaka, Toshiyuki Arai, Souichi Adachi, Akifumi Takaori-Kondo
- Organizer
  第73回日本血液学会総会
- Place of Presentation
  名古屋(名古屋国際会議場)
- Data Source
  KAKENHI-PROJECT-23659740
[Presentation] Singlet oxygen is essential for neutrophil extracellular trap formation.2011
- Author(s)
  Yamashita K, Nishinaka Y, Arai T, Adachi S, Takaori-Kondo A.
- Organizer
  第73回日本血液学会総会
- Place of Presentation
  名古屋市、名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] Singlet oxygen is essential for neutrophil extracellular trap formation2011
- Author(s)
  Kouhei Yamashita
- Organizer
  第73回日本血液学会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-21390433
[Presentation] Singlet oxygen is essential for neutrophil extracellular trap formation2011
- Author(s)
  Yamashita K, Nishinaka Y, Arai T, adachi S, Takaori-Kondo A
- Organizer
  第73回日本血液学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] 好中球の殺菌作用-活性酸素の役割2010
- Author(s)
  山下浩平
- Organizer
  第84回日本感染症学会総会
- Place of Presentation
  京都(招待講演)
- Data Source
  KAKENHI-PROJECT-20591200
[Presentation] 細胞内で発生させた一重項酸素による細胞死に対するエダラボンの効果2010
- Author(s)
  西中瑶子、荒井俊之、山下浩平、足立壮一
- Organizer
  第19回日本CellDeath学会
- Place of Presentation
  名古屋(愛知県産業労働センター)
- Year and Date
  2010-07-31
- Data Source
  KAKENHI-PROJECT-21390433
[Presentation] 好中球の殺菌作用-活性酸素の役割2010
- Author(s)
  山下浩平
- Organizer
  第84回日本感染症学会総会教育講演
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591200
[Presentation] ATRA症候群における血管透過性亢進病態形成への活性酸素関与の可能性の検討2009
- Author(s)
  三好隆史、山下浩平、荒井俊之、笹田昌孝、内山卓
- Organizer
  第71回日本血液学会総会
- Place of Presentation
  京都(京都国際会議場)
- Data Source
  KAKENHI-PROJECT-21390433
[Presentation] N-アセチルシステインの一重項酸素消去能と細胞死について2009
- Author(s)
  西中瑶子、荒井俊之、三好隆史、山下浩平、足立壮一
- Organizer
  第18回日本アポトーシス研究会学術集会
- Place of Presentation
  長崎(長崎大学)
- Year and Date
  2009-08-02
- Data Source
  KAKENHI-PROJECT-21390433
[Presentation] ATRA症候群における血管透過性亢進病態形成への活性酸素関与の可能性の検討2009
- Author(s)
  三好隆史, 山下浩平, 荒井俊之, 笹田昌孝, 内山卓
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591200
[Presentation] 敗血症におけるIL-8の血管内皮細胞に対する作用についての検討2008
- Author(s)
  三好隆史, 山下浩平, 伊藤洋志, 山本孝吉, 笹田昌孝
- Organizer
  第82回日本感染症学会総会
- Place of Presentation
  松江
- Data Source
  KAKENHI-PROJECT-20591200
[Presentation] 敗血症病態におけるIL-8の血管内皮細胞に対する作用の検討2008
- Author(s)
  三好隆史, 山下浩平, 荒井俊之, 山本孝吉, 内山卓, 笹田昌孝
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591200
[Presentation] 難治性非腫瘍性造血器疾患の病態と新しい治療戦略-好中球機能異常症2008
- Author(s)
  山下浩平
- Organizer
  第89回近畿血液学地方会特別講演
- Place of Presentation
  枚方
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-20591200
[Presentation] 難治性非腫瘍性造血器疾患の病態と新しい治療戦略-好中球機能異常症2008
- Author(s)
  山下浩平
- Organizer
  第89回近畿血液学地方会
- Place of Presentation
  枚方
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-20591200
[Presentation] 敗血症におけるIL-8の新たな役割の解明-血管内皮細胞の活性酸素産生に対する作用-2007
- Author(s)
  三好隆史、山下浩平、荒井俊之, ら
- Organizer
  第69回日本血液学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390428
[Presentation] The new role of interleukin-8 in sepsis (Reactive oxygen production from endothelial cells by IL-B)2007
- Author(s)
  Miyoshi, T., Yamashita, K., Arai, T., Itoh, H., Uchiyama, T., Sasada, M
- Organizer
  The 69th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390428
[Presentation] 敗血症におけるIL-8の新たな役割の解明-血管内皮細胞の活性酸素産生に対する作用-。2007
- Author(s)
  三好隆史、山下浩平、荒井俊之、伊藤洋志、内山卓、笹田昌孝
- Organizer
  第69回日本血液学会総会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390428
[Presentation] Photoactivation of pterin derivative induces apoptotic and necrotic cell death on a CTCL cell line2006
- Author(s)
  Tsunemine, H., Yamashita, K., Arai, T., Sasada, M., Uchiyama, T
- Organizer
  The 68th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Fukuoka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390428
[Presentation] 細胞透過性プテリン化合物の光化学反応が誘導する皮膚T細胞性リンパ腫細胞株における細胞死の解析。2006
- Author(s)
  常峰紘子、山下浩平、荒井俊之、笹田昌孝、内山卓
- Organizer
  第68回日本血液学会総会・第48回日本臨床血液学会総会
- Place of Presentation
  福岡
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390428
[Presentation] Plasmacytoid dendritic cells activated by neutrophil extracellular traps contribute to the pathogenesis of IgG4-related disease.
- Author(s)
  Arai Y, Yamashita K, Mizugishi K, Takaori-Kondo A.
- Organizer
  Annual European Congress of Rheumatology EULAR 2013.
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] 同種造血幹細胞移植後の低ガンマグロブリン血症に関する後方視的解析．
- Author(s)
  新井康之, 山下浩平, 近藤忠一, 北野俊行, 高折晃史．
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591474
[Presentation] Uric Acid Induces NADPH Oxidase-Independent Neutrophil Extracellular Trap Formation.
- Author(s)
  Arai Y, Nishinaka Y, Arai T, Mizugishi K, Adachi S, Takaori-Kondo A, Yamashita K.
- Organizer
  55th Annual Meeting of the American Society of Hematology.
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23591474

1. ARAI Toshiyuki (80175950)

# of Collaborated Projects: 4 results

# of Collaborated Products: 22 results
2. ENDO Nobuyuki (30359244)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. Mizugishi Kiyomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. KAWABATA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. KUDO Masatoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. UCHIDA Kazushige

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 櫻井俊治

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 高折晃史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 小柳義夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 中本裕士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamashita Kouhei 山下 浩平

YAMASHITA Kouhei 山下 浩平

Research Projects

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Co-Researchers

自然免疫に着目した、川崎病の病態解明および新規治療法の開発Principal Investigator

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The role of neutrophil extracellular traps in the pathogenesis of chronic GVHDPrincipal Investigator

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The role of neutrophil extracellular traps in the pathogenesis of immunological, inflammatory, or thrombotic diseasesPrincipal Investigator

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Analysis of a mechanism of neutrophil extracellular trap (NET) fromation and a role of NETs in infectious and inflammatory diseases.Principal Investigator

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Development of the novel compound which specifically scavenges singlet oxygen extra- and intracellularly.

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Determination of the active reactive oxygen species that generated in cells during ischemia-reperfusion and selection of its specific scavenger.

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RNA干渉を用いた血管内皮細胞インターロイキン発現抑制による敗血症組織傷害の緩和

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Study of the mechanism of ozone production and application for enhancement of bactericidal activity in human neutrophilsPrincipal Investigator

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Protection against ischemia-reperfusion injury using a short interfering RNA that inhibits the activity of myeloperoxidase

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[Journal Article] Exaggerated neutrophil extracellular trap formation in Kawasaki disease: A key phenomenon behind the outbreak in western countries?2020

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[Journal Article] Neutrophil extracellular traps are critical for pregnancy loss in sphingosine kinase-deficient mice on 129Sv/C57BL/6 background.2017

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[Journal Article] Chronic Fibro-Inflammatory Responses in Autoimmune Pancreatitis Depend on IFN-α and IL-33 Produced by Plasmacytoid Dendritic Cells.2017

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[Journal Article] Phagocytosis by human monocytes is required for the secretion of presepsin.2015

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[Journal Article] Enhancement of neutrophil autophagy by an IVIG preparation against multi-drug-resistant bacteria as well as drug sensitive strains.2015

Yamashita Kouhei 山下浩平

YAMASHITA Kouhei 山下浩平

[Journal Article] Enhancement of neutrophil autophagy by an IVIG preparation against　multi-drug-resistant bacteria as well as drug sensitive strains.2015

[Journal Article] 自己免疫性膵炎の診断について　診断基準の変遷と診断の現状2015