Ogawa Takashi 小川崇

… Alternative Names

小川崇オガワタカシ

OGAWA Takashi 小川崇

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Researcher Number	80405018
Other IDs
Affiliation (Current)	2025: 香川大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2025: 香川大学, 医学部, 助教 2021: 香川大学, 医学部, 助教 2014 – 2015: 香川大学, 医学部, 助教 2011 – 2012: 香川大学, 医学部, 助教 2010: 横浜市立大学, 大学院・生命ナノシステム科学研究科, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 50010:Tumor biology-related / Pathological medical chemistry / Tumor biology Except Principal Investigator Biological Sciences
Keywords	Principal Investigator ガレクチン / 大腸がん / 細胞内シグナル / 細胞増殖 / CRISPR / ツメガエル / 腸 / レクチン / 消化管 / ECM … More / 浸潤 / がん / プロセシング / ラミニン / がん微小環境 … More Except Principal Investigator 細胞接着 / マトリプターゼ / ラミニン5 / 細胞移動 / マトリライシン / 阻害剤 / プロテアーゼ / 腫瘍増殖 / 浸潤・転移 / がん / 細胞外マトリックス / 上皮-間葉変換(EMT) / 細胞接着分子 / 転移 / がん浸潤 / MMP / ラミニン / 浸潤 / 基底膜 / がん転移 Less

ガレクチン4の生理的・病理的役割の解明と腸疾患治療への応用Principal Investigator
- Principal Investigator
  
  小川崇
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kagawa University
ガレクチン4の糖鎖結合活性非依存的な大腸がん抑制機構の解明Principal Investigator
- Principal Investigator
  
  小川崇
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kagawa University
Biological activity of galectin-4 and its roles in colorectal cancer and normal tissue.Principal Investigator
- Principal Investigator
  
  Ogawa Takashi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagawa University
Roles of laminin g2 chain in tumor growth and invasion.Principal Investigator
- Principal Investigator
  
  OGAWA Takashi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kagawa University
Interaction of cancer cells with basement membrane proteins
- Principal Investigator
  
  MIYAZAKI Kaoru
- Project Period (FY)
  2005 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University

All 2022 2021 2016 2015 2013 2012 2011 2010 2009 2008 2007 2005 Other

All Journal Article Presentation Book

[Book] 細胞外マトリックス分子と細胞接着。「タンパク質科学-構造・物性・機能」2005
- Author(s)
  小川崇, 宮崎香(分担)
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-17014077
[Journal Article] Crystal structure and conformational stability of a galectin-1 tandem-repeat mutant with a short linker2022
- Author(s)
  Yasuhiro Nonaka, Takashi Ogawa, Hiroki Shoji, Nozomu Nishi, Shigehiro Kamitori, Takanori Nakamura
- Journal Title
  
  Glycobiology
  
  Volume: 32 Issue: 3 Pages: 251-259
- DOI
  10.1093/glycob/cwab101
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07151, KAKENHI-PROJECT-21K09526
[Journal Article] Modulation of the carbohydrate-binding specificity of two Xenopus proto-type galectins by site-directed mutagenesis2021
- Author(s)
  Yasuhiro Nonaka, Takashi Ogawa, Hiroki Shoji, Nozomu Nishi, Shigehiro Kamitori, Takanori Nakamura
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  
  Volume: 1869 Issue: 10 Pages: 140684-140684
- DOI
  10.1016/j.bbapap.2021.140684
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07151, KAKENHI-PROJECT-21K09526
[Journal Article] Cooperative interactions of oligosaccharide and peptide moieties of a glycopeptide derived from IgE with galectin-92016
- Author(s)
  Nakakita, S.-I., Itoh, A., Nakakita, Y., Nonaka, Y., Ogawa, T., Nakamura, T., Nishi, N.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 291 Issue: 2 Pages: 968-979
- DOI
  10.1074/jbc.m115.694448
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06974, KAKENHI-PROJECT-26860213
[Journal Article] 1)Crystal structure of a Xenopus laevis skin proto-type galectin, close to but distinct from galectin-12015
- Author(s)
  Nonaka Y, Ogawa T, Yoshida H, Shoji H, Nishi N, Kamitori S, Nakamura T
- Journal Title
  
  Glycobiology
  
  Volume: 25 Pages: 792-803
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860213
[Journal Article] Crystal structure of a Xenopus laevis skin proto-type galectin, close to but distinct from galectin-12015
- Author(s)
  Nonaka Y, Ogawa T, Yoshida H, Shoji H, Nishi N, Kamitori S, Nakamura T
- Journal Title
  
  Glycobiology
  
  Volume: 印刷中 Issue: 7 Pages: 792-803
- DOI
  10.1093/glycob/cwv020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462502, KAKENHI-PROJECT-26560242, KAKENHI-PROJECT-26860213
[Journal Article] Optimization of the inter-domain structure of galectin-9 for recombinant production.2013
- Author(s)
  Itoh A, Fukata Y, Miyanaka H, Nonaka Y, Ogawa T, Nakamura T, Nishi N.
- Journal Title
  
  Glycobiology. Glycobiology.
- Data Source
  KAKENHI-PROJECT-23701059
[Journal Article] Self-association of the galectin-9 C-terminal domain via the opposite surface of the sugar-binding site2013
- Author(s)
  Nonaka, Y., Ogawa, T., Oomizu, S., Nakakita, S., Nishi, N., Kamitori, S., Hirashima, M. & Nakamura, T
- Journal Title
  
  J. Biochem
  
  Volume: 153 Issue: 5 Pages: 463-471
- DOI
  10.1093/jb/mvt009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370054, KAKENHI-PROJECT-23591438, KAKENHI-PROJECT-23701059
[Journal Article] Optimization of the inter-domain structure of galectin-9 for recombinant production.2013
- Author(s)
  Itoh A, Fukata Y, Miyanaka H, Nonaka Y, Ogawa T, Nakamura T, Nishi N.
- Journal Title
  
  Glycobiology.
  
  Volume: Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701059
[Journal Article] Self-association of the galectin-9 C-terminal domain via the opposite surface of the sugar-binding site.2013
- Author(s)
  Nonaka Y, Ogawa T, Oomizu S, Nakakita S, Nishi N, Kamitori S, Hirashima M, Nakamura T.
- Journal Title
  
  J Biochem. J Biochem.
- NAID
  40019646873
- Data Source
  KAKENHI-PROJECT-23701059
[Journal Article] Epithelial mesenchymal transition stimulates human cancer cells to extend microtubule-based invasiveprotrusions and suppresses cell growth in collagen gel.2012
- Author(s)
  Oyanagi J, Ogawa T, Sato H, Higashi S, Miyazaki K.
- Journal Title
  
  PLoS One
  
  Volume: 7(12)
- Data Source
  KAKENHI-PROJECT-23701059
[Journal Article] Epithelial-mesenchymal transition stimulates human cancer cells to extend microtubule-based invasive protrusions and suppresses cell growth in collagen gel.2012
- Author(s)
  Oyanagi J, Ogawa T, Sato H, Higashi S, Miyazaki K.
- Journal Title
  
  PLoS One.
  
  Volume: 7(12) Issue: 12 Pages: e53209-e53209
- DOI
  10.1371/journal.pone.0053209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701059
[Journal Article] Laminin-3B11, a novel vascular type laminin capable of inducing prominent lamellipodial protrusions in microvascular endothelial cells.2010
- Author(s)
  Mori, T., Ono, K., Kariya, Y., Ogawa, T., Higashi, S., Miyazaki, K.
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 35068-35078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014077
[Journal Article] Expression of laminin gamma2 chain monomer enhances invasive growth of human carcinoma cells in vivo.2010
- Author(s)
  Tsubota, Y., Ogawa, T., Oyanagi, J., Nagashima, Y., Miyazaki, K.
- Journal Title
  
  Int.J.Cancer 127
  
  Pages: 2031-2041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014077
[Journal Article] 癌の基底膜浸潤におけるEMT-細胞外マトリックス分子の作用2008
- Author(s)
  小川崇、宮崎香
- Journal Title
  
  細胞工学 27
  
  Pages: 348-352
- Data Source
  KAKENHI-PROJECT-17014077
[Journal Article] Localization of laminin alpha3B chain in vascular and epithelial basement membranes of normal human tissues and its down-regulation in skin cancers.2008
- Author(s)
  Kariya Y, Mori T, Yasuda C, Watanabe N, Kaneko Y, Nakashima Y, Ogawa T, Miyazaki K.
- Journal Title
  
  J.Mol.Histol. 39
  
  Pages: 435-446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014077
[Journal Article] Localization of laminin alpha3B chain in vascular and epithelial basement membranes of normal human tissues and its down-regulation in skin cancers2008
- Author(s)
  Kariya Y, Mori T, Yasuda C, Watanabe N, Kaneko Y, Nakashima Y, Ogawa T, Miyazaki K
- Journal Title
  
  J Mol Histol 39
  
  Pages: 435-446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014077
[Journal Article] The short arm of laminin gamma2 chain of laminin-5(laminin-332)binds syndecan-1 and regulates cellular adhesion and migration by suppressing phosphorylation of integrin beta4 chain.2007
- Author(s)
  Ogawa, T., Miyazaki, K., et. al.
- Journal Title
  
  Mol. Biol. Cell 18
  
  Pages: 1621-1633
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014077
[Journal Article] The short arm of laminin.2 chain of laminin-5 (laminin-332) binds syndecan-1 and regulates cellular adhesion and migration by suppressing phosphorylation of integrin.4 chain.2007
- Author(s)
  Ogawa, T., Tsubota, Y., Hashimoto, J., Miyazaki, K.
- Journal Title
  
  Mol.Biol.Cell 18
  
  Pages: 1621-1633
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014077
[Journal Article] The short arm of laminin gamma2 chain of laminin-5 (laminin-332) binds syndecan-1 and regulates cellular adhesion and migration by suppressing phosphorylation of integrin beta4 chain.2007
- Author(s)
  Ogawa, T., Miyazaki, K.et al.
- Journal Title
  
  Mol. Biol. Cell (印刷中)
- Data Source
  KAKENHI-PROJECT-17014077
[Journal Article] Laminin-5 suppresses chondrogenic differentiation of murine teratocarcinoma cell line ATDC5.2005
- Author(s)
  Hashimoto, J., Ogawa, T., Tsubota, Y., Miyazaki, K.
- Journal Title
  
  Exp.Cell.Res. 310
  
  Pages: 256-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014077
[Journal Article] Regulation of biological activity and matrix assembly of laminin-5 by COOH-terminal, LG4-5 domain of alfa3 chain.2005
- Author(s)
  Tsubota, Y., Yasuda, C., Kariya, Y., Ogawa, T., Hirosaki, T., Mizushima, H., Miyazaki, K.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 14370-14377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014077
[Presentation] ヒト大腸がんおよび正常腸組織におけるガレクチン-4の発現及び機能解析2021
- Author(s)
  小川崇、野中康宏、東海林博樹、舘野浩章、平林淳、西望、中村隆範
- Organizer
  第94回日本生化学会大会　（オンライン開催）
- Data Source
  KAKENHI-PROJECT-21K07151
[Presentation] Functional and expression analysis of Galectin-4 in Xenopus digestive tract and human colon carcinoma2015
- Author(s)
  小川崇，東海林博樹，野中康宏, 舘野浩章, 平林淳, 西望，中村隆範
- Organizer
  BMB2015(第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会）
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26860213
[Presentation] 大腸がんにおけるガレクチン4の役割2015
- Author(s)
  Takashi Ogawa
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26860213
[Presentation] ツメガエル消化管及びヒト大腸がん細胞におけるガレクチン 4 の発現及び機能解析2012
- Author(s)
  小川崇,東海林博樹,野中康宏, 舘野浩章, 平林淳, 西望,中村隆範
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23701059
[Presentation] Laminin Gamma2 Chain Promotes Invasion of Tumor Cells into Vascular Endothelial Cell Layer In Vitro2012
- Author(s)
  Sato H., Ogawa T., Eriko K., Oyanagi J., Higashi S., and Miyazaki K
- Organizer
  14th International Biennial Congress of the Metastasis Research　Society
- Place of Presentation
  Brisbane, Australia
- Data Source
  KAKENHI-PROJECT-23701059
[Presentation] ツメガエル消化管及びヒト大腸がん細胞におけるガレクチン4の発現及び機能解析2012
- Author(s)
  小川崇，東海林博樹，野中康宏, 舘野浩章, 平林淳, 西望，中村隆範
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23701059
[Presentation] Laminin Gamma2 Chain Promotes Invasion ofTumor Cells into Vascular Endothelial Cell LayerIn Vitro2012
- Author(s)
  Sato H., Ogawa T., Eriko K., Oyanagi J., Higashi S., and Miyazaki K
- Organizer
  14th International Biennial Congress of the Metastasis Research Society
- Place of Presentation
  オーストラリアブリスベン
- Data Source
  KAKENHI-PROJECT-23701059
[Presentation] アフリカツメガエル消化管におけるガレクチンファミリーの発現解析2011
- Author(s)
  小川崇、東海林博樹、野中康宏、舘野浩章、平林淳、西望、中村隆範
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会合同大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23701059
[Presentation] がん浸潤マーカー分子ラミニンγ2鎖の機能2009
- Author(s)
  宮崎香、小川崇
- Organizer
  第18回日本がん転移学会学術集会・総会
- Place of Presentation
  旭川グランドホテル(北海道)
- Data Source
  KAKENHI-PROJECT-17014077
[Presentation] がんの基底膜浸潤におけるラミニンγ2鎖の発現と上皮-間葉変換(EMT)2009
- Author(s)
  小川崇、宮崎香, 他
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫>
- Data Source
  KAKENHI-PROJECT-17014077
[Presentation] 癌の基底膜浸潤におけるラミニンY2鎖の発現と上皮-間葉変換(EMT)2008
- Author(s)
  小川崇、清水翔太、宮崎香
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-17014077
[Presentation] ラミニンY2鎖の癌の悪性増殖やEMTのおける役割2008
- Author(s)
  小川崇、宮崎香
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-17014077
[Presentation] 新規ラミニンアイソフォームラミニン3B11(ラミニン6B)の発現と機能解析2008
- Author(s)
  森泰三、小川崇、小野孝太、吉村祐太、苅谷慶喜、宮崎香
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-17014077
[Presentation] ヒトがん細胞におけるラミニン5(ラミニン332)構成鎖の常発現と腫瘍増殖におけるその意義2008
- Author(s)
  小川崇、宮崎香
- Organizer
  第17回日本がん転移学会学術集会・総会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-17014077
[Presentation] ツメガエル消化管およびヒト大腸がん細胞におけるガレクチン4の発現及び機能解析
- Author(s)
  小川崇，東海林博樹，野中康宏, 舘野浩章, 平林淳, 西望，中村隆範
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26860213
[Presentation] Biological activity of galectin-4 and its roles in CRCs growth.
- Author(s)
  Takashi Ogawa
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26860213

1. MIYAZAKI Kaoru (70112068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
2. HIGASHI Shouichi (10275076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. NAKAKITA Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. NONAKA Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 西望

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 神鳥成弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 東海林博樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ogawa Takashi 小川 崇

小川 崇 オガワ タカシ

OGAWA Takashi 小川 崇

Research Projects

Research Products

Co-Researchers

ガレクチン4の生理的・病理的役割の解明と腸疾患治療への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ガレクチン4の糖鎖結合活性非依存的な大腸がん抑制機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Biological activity of galectin-4 and its roles in colorectal cancer and normal tissue.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of laminin g2 chain in tumor growth and invasion.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Interaction of cancer cells with basement membrane proteins

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 細胞外マトリックス分子と細胞接着。「タンパク質科学-構造・物性・機能」2005

Author(s)

Publisher

Data Source

[Journal Article] Crystal structure and conformational stability of a galectin-1 tandem-repeat mutant with a short linker2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modulation of the carbohydrate-binding specificity of two Xenopus proto-type galectins by site-directed mutagenesis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cooperative interactions of oligosaccharide and peptide moieties of a glycopeptide derived from IgE with galectin-92016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 1)Crystal structure of a Xenopus laevis skin proto-type galectin, close to but distinct from galectin-12015

Author(s)

Journal Title

Data Source

[Journal Article] Crystal structure of a Xenopus laevis skin proto-type galectin, close to but distinct from galectin-12015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Optimization of the inter-domain structure of galectin-9 for recombinant production.2013

Author(s)

Journal Title

Data Source

[Journal Article] Self-association of the galectin-9 C-terminal domain via the opposite surface of the sugar-binding site2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Optimization of the inter-domain structure of galectin-9 for recombinant production.2013

Author(s)

Journal Title

Data Source

[Journal Article] Self-association of the galectin-9 C-terminal domain via the opposite surface of the sugar-binding site.2013

Author(s)

Journal Title

Ogawa Takashi 小川崇

小川崇オガワタカシ

OGAWA Takashi 小川崇