Sozu Takashi 寒水孝司

… Alternative Names

Takashi Sozu 寒水孝司

SOZU Takashi 寒水孝司

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Researcher Number	80408723
Other IDs
Affiliation (Current)	2025: 東京理科大学, 工学部情報工学科, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 東京理科大学, 工学部情報工学科, 教授 2016 – 2018: 東京理科大学, 工学部情報工学科, 准教授 2016: 東京理科大学, 工学部, 准教授 2015: 東京理科大学, 工学部第一部経営工学科, 准教授 2014: 京都大学, 医学研究科, 准教授 … More 2012 – 2014: 京都大学, 医学(系)研究科(研究院), 准教授 2013: 京都大学, 大学院・医学研究科, 准教授 2010 – 2011: 京都大学, 医学研究科, 准教授 2008 – 2009: 大阪大学, 臨床医工学融合研究教育センター, 特任准教授(常勤) Less
Review Section/Research Field	Principal Investigator Basic Section 60030:Statistical science-related / Statistical science / Epidemiology and preventive medicine / Statistical science Except Principal Investigator Statistical science / Statistical science
Keywords	Principal Investigator 医薬品開発 / 多重性 / 臨床試験 / 既存データ / 累積データ / リアルワールドデータ / Bayes / Bayesian shrinkage prior / ヒストリカルデータ / 試験期間 … More / 2段階試験 / 事象時間データ / 3群比較試験 / 感度解析 / 標本サイズ設計 / 標的部分集団 / 階層モデル / Bayes法 / 生存時間解析 / 多群比較臨床試験 / 臨床試験デザイン / 群逐次デザイン / サンプルサイズ / 費用効率 / エンドポイント / 主要評価変数 / 治験 / 症例数設計 / 非劣性 / 優越性 / 生物統計学 / 標本サイズ … More Except Principal Investigator 臨床試験 / 医薬品開発 / エンリッチメントデザイン / 多重エンドポイント / 個別化医療 / 適応的デザイン / 生物統計学 / 予測解析 / バイオマーカー / 統計解析 / ゲノムデータ解析 / ゲノムデータの解析 / 診断法開発 / 先端医療技術の開発 / 臨床試験の計画と解析 / 先端医療技術 / データ解析 / 統計的デザイン / 予測バイオマーカ / 標本サイズ再計算 / 生存時間データ / 統計科学 / 群逐次デザイン / 多重性 / 国際共同試験 / Enrichmentデザイン / 部分集団解析 / 国際研究者交流 / 国際共同臨床試験 / 確率化操作 / 標本サイズの設定 / 多重評価指標 / 統計的シミュレーション / 多重評価項目 / 標本サイズ Less

Evaluation and construction of the Bayesian method to accelerate drug developmentPrincipal Investigator
- Principal Investigator
  
  寒水孝司
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 60030:Statistical science-related
- Research Institution
  Tokyo University of Science
A statistical method for achieving efficient and rapid clinical trialsPrincipal Investigator
- Principal Investigator
  
  Takashi Sozu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 60030:Statistical science-related
- Research Institution
  Tokyo University of Science
A study design for achieving efficient and rapid clinical trialsPrincipal Investigator
- Principal Investigator
  
  Sozu Takashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Statistical science
- Research Institution
  Tokyo University of Science
Statistical frameworks for efficient decision-making in complex clinical trial designs
- Principal Investigator
  
  Hamasaki Toshimitsu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Statistical science
- Research Institution
  Osaka University
A new clinical trial design considering the efficiency of multiple primary endpointsPrincipal Investigator
- Principal Investigator
  
  SOZU Takashi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Epidemiology and preventive medicine
- Research Institution
  Kyoto University
Design and statistical analysis in translational clinical trials
- Principal Investigator
  
  Matsui Shigeyuki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Statistical science
- Research Institution
  Nagoya University
  The Institute of Statistical Mathematics
Statistical Issues in Complex Medical Product Development
- Principal Investigator
  
  TOSHIMITSU Hamasaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Statistical science
- Research Institution
  Osaka University
Design and Analysis of Clinical Trials with Multiple Co-primary EndpointsPrincipal Investigator
- Principal Investigator
  
  SOZU Takashi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Statistical science
- Research Institution
  Kyoto University
Statistical Methodologies for Improving Predictability in Clinical Research and Development of Drugs
- Principal Investigator
  
  HAMASAKI Toshimitsu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Statistical science
- Research Institution
  Osaka University

[Book] Sample Size Determination in Clinical Trials with Multiple Primary Endpoints2015
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T, Evans SR
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25870332
[Journal Article] Copula-Based Model for Incorporating Single-Agent Historical Data into Dual-Agent Phase I Cancer Trials2023
- Author(s)
  Hashizume Koichi、Tsuchida Jun、Sozu Takashi
- Journal Title
  
  Statistics in Biopharmaceutical Research
  
  Volume: - Issue: 1 Pages: 71-88
- DOI
  10.1080/19466315.2023.2190932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K11717
[Journal Article] Using horseshoe prior for incorporating multiple historical control data in randomized controlled trials2022
- Author(s)
  Ohigashi Tomohiro、Maruo Kazushi、Sozu Takashi、Gosho Masahiko
- Journal Title
  
  Statistical Methods in Medical Research
  
  Volume: - Issue: 7 Pages: 1392-1404
- DOI
  10.1177/09622802221090752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K11187, KAKENHI-PROJECT-20K11717
[Journal Article] Predicting study duration in clinical trials with a time-to-event endpoint2021
- Author(s)
  Machida R. Fujii Y. Sozu T
- Journal Title
  
  Statistics in Medicine
  
  Volume: 40 Issue: 10 Pages: 2413-2421
- DOI
  10.1002/sim.8911
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K11717
[Journal Article] Sizing clinical trials when comparing bivariate time-to-event outcomes2017
- Author(s)
  Sugimoto T, Hamasaki T, Evans S.R., Sozu T.
- Journal Title
  
  Statistics in Medicine
  
  Volume: 36 Issue: 9 Pages: 1363-1382
- DOI
  10.1002/sim.7225
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26330032, KAKENHI-PROJECT-26330038, KAKENHI-PROJECT-16K09046, KAKENHI-PROJECT-17K00054, KAKENHI-PROJECT-17K00069
[Journal Article] Reducing unnecessary measurements in clinical trials with multiple primary endpoints2016
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Journal Title
  
  Journal of Biopharmaceutical Statistics
  
  Volume: 26 Issue: 4 Pages: 631-643
- DOI
  10.1080/10543406.2015.1052497
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26330038
[Journal Article] Sample size considerations in clinical trials when comparing two interventions using multiple co-primary binary relative risk contrasts2015
- Author(s)
  Ando Y, Hamasaki T, Evans SR, Asakura K, Sugimoto T, Sozu T, Ohno Y
- Journal Title
  
  Statistics in Biopharmaceutical Research
  
  Volume: 掲載確定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870332
[Journal Article] Group-sequential designs when considering two binary outcomes as co-primary endpoints2015
- Author(s)
  Asakura K, Hamasaki T, Evans S, Sugimoto T, Sozu T
- Journal Title
  
  Applied Statistics in Biomedicine and Clinical Trials Design
  
  Volume: 14 Pages: 235-262
- DOI
  10.1007/978-3-319-12694-4_14
- ISBN
  9783319126937, 9783319126944
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26330038
[Journal Article] Sample size considerations in clinical trials when comparing two interventions using multiple co-primary binary relative risk contrasts2015
- Author(s)
  Ando Y, Hamasaki T, Evans S, Asakura K, Sugimoto T, Sozu T, Ohno, Y
- Journal Title
  
  Statistics in Biopharmaceutical Research
  
  Volume: 7 Issue: 2 Pages: 81-94
- DOI
  10.1080/19466315.2015.1006373
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26330038, KAKENHI-PROJECT-15K15957
[Journal Article] A new procedure of one-sided test in clinical trials with multiple endpoints2015
- Author(s)
  Nakazuru Y, Sozu T, Hamada C, Yoshimura I
- Journal Title
  
  Japanese Journal of Biometrics
  
  Volume: 35 Pages: 17-35
- NAID
  130004840600
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25870332
[Journal Article] Reducing unnecessary measurements in clinical trials with multiple primary endpoints2015
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Journal Title
  
  Journal of Biopharmaceutical Statistics
  
  Volume: 掲載確定
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25870332
[Journal Article] Group-sequential strategies in clinical trials with multiple co-primary outcomes2015
- Author(s)
  Hamasaki H, Asakura K, Evans, SR, Sugimoto T, Sozu T
- Journal Title
  
  Statistics in Biopharmaceutical Research
  
  Volume: 7 Issue: 1 Pages: 36-54
- DOI
  10.1080/19466315.2014.1003090
- NAID
  120005619770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870332, KAKENHI-PROJECT-26330032, KAKENHI-PROJECT-26330038
[Journal Article] Sample size determination in group-sequential clinical trials with two co-primary endpoints2014
- Author(s)
  Asakura, K., Hamasaki, T., Sugimoto, T., Hayashi, K., Evans, S., Sozu T
- Journal Title
  
  Statistics in Medicine
  
  Volume: (First published online) Issue: 17 Pages: 2897-2913
- DOI
  10.1002/sim.6154
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22300096, KAKENHI-PROJECT-23500348, KAKENHI-PROJECT-24700276, KAKENHI-PROJECT-25870332, KAKENHI-PROJECT-26330032, KAKENHI-PROJECT-26330038
[Journal Article] Sample size determination for clinical trials with co-primary outcomes. Exponential event-times2013
- Author(s)
  Hamasaki T, Sugimoto T, Evans SR, Sozu T
- Journal Title
  
  Pharmaceutical Statistics
  
  Volume: 12 Issue: 1 Pages: 28-34
- DOI
  10.1002/pst.1545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500348, KAKENHI-PROJECT-23700336
[Journal Article] A logrank test-based method for sizing clinical trials with two co-primary time-to-events endpoints2013
- Author(s)
  Sugimoto T, Sozu T, Hamasaki T, Evans SR
- Journal Title
  
  Biostatistics
  
  Volume: 14 Issue: 3 Pages: 409-421
- DOI
  10.1093/biostatistics/kxs057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500348, KAKENHI-PROJECT-23700336
[Journal Article] 主要評価変数が複数ある臨床試験の統計的諸問題2013
- Author(s)
  寒水孝司，杉本知之，濱崎俊光
- Journal Title
  
  計量生物学
  
  Volume: 34 Pages: 35-52
- NAID
  10031194714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870332
[Journal Article] Statistical Issues in Clinical Trials with Multiple Primary Endpoints2013
- Author(s)
  寒水孝司・杉本知之・濱崎俊光
- Journal Title
  
  Japanese Journal of Biometrics
  
  Volume: 34 Issue: 1 Pages: 35-52
- DOI
  10.5691/jjb.34.35
- NAID
  10031194714
- ISSN
  0918-4430, 2185-6494
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500348
[Journal Article] A convenient formula for sample size calculations in clinical trials with multiple co-primary continuous endpoints2012
- Author(s)
  Sugimoto T, Sozu T, Hamasaki T
- Journal Title
  
  Pharmaceutical Statistics
  
  Volume: 11 Issue: 2 Pages: 118-128
- DOI
  10.1002/pst.505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700290, KAKENHI-PROJECT-23500348, KAKENHI-PROJECT-23700336
[Journal Article] Sample size determination in clinical trials with multiple co-primary endpoints including mixed continuous and binary variables2012
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Journal Title
  
  Biometrical Journal
  
  Volume: 54 Issue: 5 Pages: 716-729
- DOI
  10.1002/bimj.201100221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500348, KAKENHI-PROJECT-23700336
[Journal Article] Sample size determination in superiority clinical trials with multiple co-primary correlated endpoints2011
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Journal Title
  
  Journal of Biopharmaceutical Statistics
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500255
[Journal Article] Sample size determination in superiority clinical trials with multiple co-primary correlated end-points.2011
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Journal Title
  
  Journal of Biopharmaceutical Statistics in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500255
[Journal Article] Sample size determination in superiority clinical trials with multiple co-primary correlated endpoints2011
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Journal Title
  
  Journal of Biopharmaceutical Statistics
  
  Volume: 21 Issue: 4 Pages: 650-668
- DOI
  10.1080/10543406.2011.551329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700290, KAKENHI-PROJECT-23500348, KAKENHI-PROJECT-23700336
[Journal Article] Sample size determination in clinical trials with multiple co-primary binary endpoints.2010
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Journal Title
  
  Statistics in Medicine 29
  
  Pages: 2169-2179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500255
[Journal Article] Sample size determination in clinical trials with multiple co-primary binary endpoints2010
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Journal Title
  
  Statistics in Medicine
  
  Volume: 29 Pages: 2169-2179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700290
[Journal Article] Sample size determination in clinical trials with multiple co-primary binary endpoints2010
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Journal Title
  
  Statistics in Medicine 2010
  
  Volume: 29(21) Issue: 21 Pages: 2169-2179
- DOI
  10.1002/sim.3972
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700290
[Journal Article] Sample size determination in clinical trials with multiple co-primary binary endpoints2010
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Journal Title
  
  Statistics in Medicine
  
  Volume: 29 Pages: 2169-2179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500255
[Presentation] Dirichlet過程混合モデルを用いたクラスタリングによる既存データ利用2023
- Author(s)
  大東智洋, 丸尾和司, 寒水孝司, 五所正彦
- Organizer
  2023年度日本計量生物学会年会
- Data Source
  KAKENHI-PROJECT-20K11717
[Presentation] A comparison of dose-finding method for incorporating single-agent historical data into dual-agent trial2023
- Author(s)
  Hashizume K, Tsuchida J, Sozu T
- Organizer
  44th Annual Conference of the International Society for Clinical Biostatistics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K11015
[Presentation] Dirichlet過程混合モデルを用いたクラスタリングによる既存データ利用法の提案2023
- Author(s)
  大東智洋, 丸尾和司, 寒水孝司, 五所正彦
- Organizer
  2023年度日本計量生物学会年会
- Data Source
  KAKENHI-PROJECT-23K11015
[Presentation] 臨床試験の被験者登録の時間変化を考慮した試験期間の不確実性の評価2022
- Author(s)
  三枝美耶, 町田龍之介, 寒水孝司
- Organizer
  2022年度日本計量生物学会年会
- Data Source
  KAKENHI-PROJECT-20K11717
[Presentation] 潜在的レスポンダーを仮定した2段階ランダム化デザインにおける治療効果の推定2022
- Author(s)
  入江佳輝, 寒水孝司, 土田潤
- Organizer
  2022年度統計関連学会連合大会
- Data Source
  KAKENHI-PROJECT-20K11717
[Presentation] 既存試験データを利用するためのBayesian shrinkage priorに基づく方法の提案2022
- Author(s)
  大東智洋, 丸尾和司, 寒水孝司, 澤本涼, 五所正彦
- Organizer
  2022年度日本計量生物学会年会
- Data Source
  KAKENHI-PROJECT-20K11717
[Presentation] Copula-based model for incorporating single-agent historical data into dual-agent phase I cancer trials2022
- Author(s)
  Hashizume K, Tsuchida J, Sozu T
- Organizer
  31st International Biometric Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11717
[Presentation] Sequential parallel comparison design における部分集団の結果変数の非正規性を考慮した検定法2021
- Author(s)
  土田潤, 宮内佑, 安藤宗司, 寒水孝司
- Organizer
  応用統計学会2021年年会
- Data Source
  KAKENHI-PROJECT-20K11717
[Presentation] 既存試験データを用いたhorseshoe priorに基づく二値応答の群間比較法2021
- Author(s)
  大東智洋, 丸尾和司, 寒水孝司, 五所正彦
- Organizer
  2021年度日本計量生物学会年会
- Data Source
  KAKENHI-PROJECT-20K11717
[Presentation] Covariate adjustment for considering between-trial heterogeneity in clinical trials using historical data for evaluating the treatment efficacy2019
- Author(s)
  Ohigashi T,Sozu T, Tsuchida J
- Organizer
  ENAR 2019 Spring Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00058
[Presentation] Breast cancer multi-arm clinical trials with multiple objectives: A literature review of major journals2018
- Author(s)
  Miyauchi Y, Nomura S, Ajisawa Y, Sozu T
- Organizer
  ENAR 2018 Spring Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00058
[Presentation] Two-stage design considering superiority and non-inferiority tests in three-arm clinical trials2018
- Author(s)
  Ajisawa Y, Nomura S, Sozu T
- Organizer
  ENAR 2018 Spring Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00058
[Presentation] Bayesian methods for evaluating the efficacy of a new treatment considering between-trial heterogeneity in clinical trials using historical data2018
- Author(s)
  Ohigashi T, Sozu T
- Organizer
  XXIX International Biometric Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00058
[Presentation] 臨床試験における累積データの不均一性を考慮して試験治療の有効性を評価するベイズ流解析法2017
- Author(s)
  加藤雄一郎, 寒水孝司
- Organizer
  2017年度日本計量生物学会年会
- Place of Presentation
  中央大学, 東京都文京区
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-16K00058
[Presentation] 標的部分集団解析を設定する臨床試験における多重比較法に関する研究2017
- Author(s)
  玉井宗一郎, 寒水孝司
- Organizer
  2017年度日本計量生物学会年会
- Place of Presentation
  中央大学, 東京都文京区
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-16K00058
[Presentation] 生存時間解析を主解析とする臨床試験の標本サイズと試験期間の設計2017
- Author(s)
  町田龍之介, 藤井陽介, 寒水孝司
- Organizer
  2017年度日本計量生物学会年会
- Place of Presentation
  中央大学, 東京都文京区
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-16K00058
[Presentation] 生存時間解析を主解析とする臨床試験の標本サイズと試験期間の設計2016
- Author(s)
  町田龍之介, 藤井陽介, 寒水孝司
- Organizer
  日本計算機統計学会第30回シンポジウム
- Place of Presentation
  プラサヴェルデ, 静岡県沼津市
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-16K00058
[Presentation] Sample size and duration of study in clinical trials with time-to-event endpoint2016
- Author(s)
  Machida R, Fujii Y, Sozu T
- Organizer
  Joint Statistical Meetings 2016
- Place of Presentation
  McCormick Place, Chicago, IL, USA
- Year and Date
  2016-08-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00058
[Presentation] Sample size determination in clinical trials with two time-to-event outcomes2016
- Author(s)
  Hamasaki T, Sugimoto T, Evans SR, Sozu T.
- Organizer
  DIA/FDA Statistics 2016 Forum
- Place of Presentation
  Bethesda, MD, USA
- Year and Date
  2016-04-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26330038
[Presentation] Sizing clinical trials when comparing two interventions using two time-to-event outcomes2015
- Author(s)
  Sugimoto T, Hamasaki T, Evans SR, Sozu T
- Organizer
  Joint Statistical Meetings 2015
- Place of Presentation
  Seattle, USA
- Year and Date
  2015-08-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26330038
[Presentation] 臨床試験における多重性の諸問題2014
- Author(s)
  寒水孝司
- Organizer
  2014年計量生物セミナー
- Place of Presentation
  キャンパスプラザ京都（京都府京都市）
- Year and Date
  2014-12-19
- Data Source
  KAKENHI-PROJECT-25870332
[Presentation] 主要評価変数が複数ある臨床試験の統計的諸問題2014
- Author(s)
  寒水孝司
- Organizer
  バイオ統計センター公開セミナー
- Place of Presentation
  久留米大学（福岡県久留米市）
- Year and Date
  2014-10-09
- Invited
- Data Source
  KAKENHI-PROJECT-25870332
[Presentation] Sample size evaluation in group sequential designs for clinical trials with two continuous endpoints as co-primary contrasts2013
- Author(s)
  Asakura K, Hayashi K, Sugimoto T, Sozu T, Hamasaki T
- Organizer
  Joint Statistical Meetings 2013
- Place of Presentation
  Montreal, Quebec, Canada
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Sample size considerations in complex clinical trials2013
- Author(s)
  Hamasaki T, Sozu T, Sugimoto T, Evans SR
- Organizer
  The 8th International Conference on Multiple Comparison Procedures
- Place of Presentation
  University of Southampton, UK
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Sample size evaluation in clinical trials with co-primary endpoints2013
- Author(s)
  Hamasaki T, Sozu T, Sugimoto T, Evans SR
- Organizer
  2013 ENAR Spring Meeting
- Place of Presentation
  Orlando, Florida, United States
- Invited
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Sample size considerations when using two time-to-event outcomes for comparing two interventions in clinical trials2013
- Author(s)
  Sugimoto T, Hamasaki T, Sozu T, Evans SR
- Organizer
  Joint Statistical Meetings 2013
- Place of Presentation
  Montreal, Quebec, Canada
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Sample size considerations in complex clinical trials2013
- Author(s)
  Hamasaki T, Sozu T, Sugimoto T, Evans SR
- Organizer
  The 8th International Conference on Multiple Comparison Procedures
- Place of Presentation
  University of Southampton, United Kingdom
- Invited
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Sample size considerations when using two time-to-event outcomes for comparing two interventions in clinical trials2013
- Author(s)
  Sugimoto T, Hamasaki T, Sozu T, Evans SR
- Organizer
  Joint Statistical Meetings 2013
- Place of Presentation
  Montr?al, Qu?bec, Canada
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Sample size determination in group sequential trials with two co-primary endpoints2012
- Author(s)
  Asakura K, Hayashi K, Sugimoto T, Sozu T, Hamasaki T
- Organizer
  The XXVIth International Biometric Conference
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Sample size determination in clinical trials with multiple correlated endpoints2012
- Author(s)
  Hamasaki T, Sozu T, Sugimoto T, Evans SR
- Organizer
  Joint Statistical Meetings 2012
- Place of Presentation
  San Diego, United States
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Adjustment methods for testing co-primary endpoints in clinical trials2012
- Author(s)
  Sozu T, Hamasaki T
- Organizer
  East Asia Regional Biometric Conference 2012
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Sample size determination in clinical trials with two correlated time-to-events endpoints as primary contrasts2012
- Author(s)
  Hamasaki T, Sugimoto T, Sozu T, Evans SR
- Organizer
  The 6th Annual FDA-DIA Statistics Forum
- Place of Presentation
  Bethesda, United States
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] 二つの主要変数をもつ群逐次試験の標本サイズの設計と評価2012
- Author(s)
  朝倉こう子・林賢一・杉本知之・寒水孝司・濱崎俊光
- Organizer
  日本計量生物学会2012年度年会・講演予稿集
- Place of Presentation
  統計数理研究所, 東京
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Adjustment methods for testing co-primary endpoints in clinical trials2012
- Author(s)
  Sozu T, Hamasaki T
- Organizer
  East Asia Regional Biometric Conference 2012（ポスター発表）
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Sample size determination in clinical trials with two correlated time-to-events endpoints as primary contrasts2012
- Author(s)
  Hamasaki T, Sugimoto T, Sozu T, Evans SR
- Organizer
  The 6th Annual FDA-DIA Statistics Forum
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] 複数の主要評価変数の費用効率を考慮した臨床試験のデザイン2012
- Author(s)
  寒水孝司・杉本知之・濱崎俊光
- Organizer
  2012年度統計関連学会連合大会
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Sample size determination in clinical trials with multiple binary relative risks2012
- Author(s)
  Hamasaki T, Evans SR, Sugimoto T, Sozu T
- Organizer
  2012 ENAR Spring Meeting
- Place of Presentation
  Washington DC, United States
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Adjustment methods for testing co-primary endpoints in clinical trials2012
- Author(s)
  Sozu T, Hamasaki T
- Organizer
  The 3rd East Asia Regional Biometric Conference 2012
- Place of Presentation
  Seoul, Korea
- Year and Date
  2012-02-23
- Data Source
  KAKENHI-PROJECT-22700290
[Presentation] Power and sample size determination in clinical trials with multiple correlated endpoints2012
- Author(s)
  Hamasaki T, Sozu T, Sugimoto T, Evans SR
- Organizer
  Advances in Clinical Trial Statistics
- Place of Presentation
  National Health Research Institute, Taiwan
- Year and Date
  2012-11-20
- Invited
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Sample size determination in clinical trials with multiple co-primary endpoints2011
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Organizer
  Joint Meeting of the 2011 Taipei International Statistical Symposium and 7th Conference of the Asian Regional Section of the IASC
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22700290
[Presentation] Sample size determination in clinical trials with multiple co-primary Endpoints2011
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Organizer
  Joint Meeting of the 2011 Taipei International Statistical Symposium and 7th Conference of the Asian Regional Section of the IASC
- Place of Presentation
  Taipei, Taiwan(招待講演)
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22700290
[Presentation] Sample size determination in clinical trials with two correlated co-primary time-to-event endpoints2011
- Author(s)
  Sugimoto T, Hamasaki T, Sozu T
- Organizer
  The 7th International Conference on Multiple Comparison Procedures
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] 複数の主要評価変数をもつ臨床試験における標本サイズの公式2011
- Author(s)
  寒水孝司・杉本知之・濱崎俊光
- Organizer
  2011年度統計関連学会連合大会
- Place of Presentation
  九州大学
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Sample size determination in clinical trials with multiple correlated endpoints2011
- Author(s)
  Sozu T, Hamasaki T, Sugimoto, T
- Organizer
  Joint Meeting of the 2011 Taipei International Statistical Symposium and the 7th Conference of Asian Regional Section of the IASC(招待講演)
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] 二つの主要変数をもつ群逐次試験の標本サイズの設計2011
- Author(s)
  朝倉こう子・林賢一・杉本知之・寒水孝司・濱崎俊光
- Organizer
  2011年度統計関連学会連合大会
- Place of Presentation
  九州大学
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] 二つの主要変数をもつ群逐次試験の標本サイズの設計2011
- Author(s)
  朝倉こう子, 林賢一, 杉本知之, 寒水孝司, 濱崎俊光
- Organizer
  2011年度統計関連学会連合大会
- Place of Presentation
  九州大学,福岡県福岡市
- Year and Date
  2011-09-06
- Data Source
  KAKENHI-PROJECT-22700290
[Presentation] Sample size determination for clinical trials with two correlated time-to-event co-primary endpoints2011
- Author(s)
  Hamasaki T, Evans S, Sugimoto T, Sozu T
- Organizer
  Joint Meeting of the 2011 Taipei International Statistical Symposium and 7th Conference of the Asian Regional Section of the IASC
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2011-12-17
- Data Source
  KAKENHI-PROJECT-22700290
[Presentation] Sample size determination for clinical trials with two correlated time-to-event co-primary endpoints2011
- Author(s)
  Hamasaki T, Evans SR, Sugimoto T, Sozu T
- Organizer
  Joint Meeting of the 2011 Taipei International Statistical Symposium and the 7th Conference of Asian Regional Section of the IASC
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] 複数の主要評価変数をもつ臨床試験における標本サイズの公式2011
- Author(s)
  寒水孝司, 杉本知之, 濱崎俊光
- Organizer
  2011年度統計関連学会連合大会
- Place of Presentation
  九州大学,福岡県福岡市
- Year and Date
  2011-09-06
- Data Source
  KAKENHI-PROJECT-22700290
[Presentation] 二つの主要変数をもつ群逐次試験の標本サイズの設計2011
- Author(s)
  朝倉こう子･林　賢一･杉本知之･寒水孝司･濱崎俊光
- Organizer
  2011年度統計関連学会連合大会
- Place of Presentation
  九州大学（福岡県）
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] 複数の主要評価変数をもつ臨床試験における標本サイズの公式2011
- Author(s)
  寒水孝司･杉本知之･濱崎俊光
- Organizer
  2011年度統計関連学会連合大会
- Place of Presentation
  九州大学（福岡県）
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Sample size determination in clinical trials with multiple correlated endpoints2011
- Author(s)
  Sozu T, Hamasaki T, Sugimoto, T
- Organizer
  Joint Meeting of the 2011 Taipei International Statistical Symposium and the 7th Conference of Asian Regional Section of the IASC
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Sample size determination in clinical trials with two correlated time-to-event endpoints2011
- Author(s)
  Sugimoto T, Hamasaki T, Sozu T
- Organizer
  The 7th International Conference on Multiple Comparison Procedures
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2011-08-31
- Data Source
  KAKENHI-PROJECT-22700290
[Presentation] 複数の主要評価変数をもつ臨床試験の症例数設計:正規変数と2値変数が存在する場合2010
- Author(s)
  寒水孝司, 杉本知之, 濱崎俊光
- Organizer
  日本計量生物学会
- Place of Presentation
  統計数理研究所,東京
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22700290
[Presentation] 複数の主要評価変数をもつ臨床試験の症例数設計:正規変数と2 値変数が存在する場合2010
- Author(s)
  寒水孝司, 杉本知之, 濱崎俊光
- Organizer
  日本計量生物学会・2010年度年会,講演予稿集,13-18
- Place of Presentation
  統計数理研究所
- Data Source
  KAKENHI-PROJECT-20500255
[Presentation] Sample size determination in clinical trials with multiple co-primary binary endpoints.2010
- Author(s)
  寒水孝司, 杉本知之, 濱崎俊光
- Organizer
  The XXVth International Biometric Conference
- Place of Presentation
  Florianopo-lis, Brazil
- Data Source
  KAKENHI-PROJECT-20500255
[Presentation] Sample size determination in clinical trials with multiple co-primary endpoints including mixed continuous and binary variables2010
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Organizer
  XXVth International Biometric Conference
- Place of Presentation
  Florianolis, Brazil
- Year and Date
  2010-12-06
- Data Source
  KAKENHI-PROJECT-22700290
[Presentation] Sample size determination in clinical trials with multiple co-primary binary endpoints2010
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Organizer
  The XXVth International Biometric Conference
- Place of Presentation
  Florianopolis, Brazil
- Year and Date
  2010-12-06
- Data Source
  KAKENHI-PROJECT-20500255
[Presentation] 複数の主要評価変数をもつ臨床試験の症例数設計:正規変数と2値変数が存在する場合2010
- Author(s)
  寒水孝司, 杉本知之, 濱崎俊光
- Organizer
  2010年度日本計量生物学会年会
- Place of Presentation
  統計数理研究所,東京都立川市
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22700290
[Presentation] Sample size determination in clinical trials with multiple co-primary endpoints including mixed continuous and binary variables2010
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Organizer
  XXVth International Biometric Conference
- Place of Presentation
  Florianopolis, Brazil
- Year and Date
  2010-12-06
- Data Source
  KAKENHI-PROJECT-22700290
[Presentation] 複数の主要評価変数をもつ臨床試験の症例数設計:正規変数と2値変数が存在する場合2010
- Author(s)
  寒水孝司, 杉本知之, 濱崎俊光
- Organizer
  日本計量生物学会
- Place of Presentation
  統計数理研究所,東京
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-20500255
[Presentation] Sample size determination in clinical trials with multiple co-primary binary endpoints.2009
- Author(s)
  寒水孝司, 杉本知之, 濱崎俊光
- Organizer
  Joint Sta-tistical Meeting 2009
- Place of Presentation
  Washington D.C.
- Data Source
  KAKENHI-PROJECT-20500255
[Presentation] Power and sample size calculations in clinical trials with multiple co-primary binary variables2009
- Author(s)
  Sozu, T., et al.
- Organizer
  Joint Statistical Meeting
- Place of Presentation
  Washington DC., USA
- Data Source
  KAKENHI-PROJECT-20500255
[Presentation] Sample size determination in clinical trials with multiple co-primary binary endpoints.2009
- Author(s)
  寒水孝司, 杉本知之, 濱崎俊光
- Organizer
  US Food and Drug Administration
- Place of Presentation
  (Invited Presentation)
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-20500255
[Presentation] Preparing the next generation of applied statistician : A global aspect2008
- Author(s)
  Sozu, T.
- Organizer
  The 15th Biopharmaceutical Applied Statistics Symposium
- Place of Presentation
  Savannah, Georgia, USA
- Data Source
  KAKENHI-PROJECT-20500255
[Presentation] Power and Sample Size Determination in Clinical Trials with Two-Correlated Relative Risks
- Author(s)
  Hamasaki T, Evans SR, Sugimoto T, Sozu T
- Organizer
  ENAR 2012 Spring Meeting
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Designing and monitoring clinical trials when considering multiple outcomes as co-primary endpoints
- Author(s)
  Hamasaki T, Sugimoto T, Sozu T.
- Organizer
  Austria-Japan Joint Statistics Workshop
- Place of Presentation
  Osaka, Japan
- Year and Date
  2015-03-23 – 2015-03-27
- Invited
- Data Source
  KAKENHI-PROJECT-26330038
[Presentation] 複数の主要評価変数の費用効率を考慮した臨床試験のデザイン
- Author(s)
  寒水孝司･杉本知之･濱﨑俊光
- Organizer
  2012年度統計関連学会連合大会
- Place of Presentation
  北海道大学，北海道
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] 二つの主要変数をもつ群逐次試験の標本サイズの設計と評価
- Author(s)
  朝倉こう子･林　賢一･杉本知之･寒水孝司･濱﨑俊光
- Organizer
  日本計量生物学会 2012年度年会
- Place of Presentation
  統計数理研究所, 立川，東京
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] Sample size evaluation in clinical trials with co-primary endpoints
- Author(s)
  Hamasaki T, Sozu T, Sugimoto T, Evans SR
- Organizer
  ENAR 2013 Spring Meeting
- Place of Presentation
  Orlando, Florida, USA
- Invited
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] A cost-effective clinical trial design with multiple primary endpoints
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T.
- Organizer
  The XXVII International Biometric Conference
- Place of Presentation
  Florence, Italy
- Year and Date
  2014-07-05 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-26330038
[Presentation] Sample size determination in clinical trials with multiple correlated endpoints
- Author(s)
  Hamasaki T, Sozu T, Sugimoto T, Evans SR
- Organizer
  Joint Statistical Meetings 2012
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-23500348
[Presentation] A cost-effective clinical trial design with multiple primary endpoints
- Author(s)
  Sozu T, Sugimoto T, Hamasaki T
- Organizer
  XXVII International Biometric Conference
- Place of Presentation
  Florence (Italy)
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-25870332

1. HAMASAKI Toshimitsu (40379243)

# of Collaborated Projects: 3 results

# of Collaborated Products: 48 results
2. SUGIMOTO Tomoyuki (70324829)

# of Collaborated Projects: 3 results

# of Collaborated Products: 49 results
3. UESAKA Hiroyuki (60446250)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 五所正彦 (70701019)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. HAYASHI Kenichi (70617274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. SUGITANI Toshifumi (70626879)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Matsui Shigeyuki (80305854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YAMAGUCHI Takuhiro (50313101)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. FUJISAWA Hironori (00301177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. DAIMON Takashi (40372156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAWAGUCHI Atsushi (60389319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ITO Yoichi (80061167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMANAKA Takeharu (00325466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HIRAKAWA Akihiro (90609330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NOMA Hisashi (70633486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 山本紘司 (10548176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 高橋佳苗 (80726761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 江口真透 (10168776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 手良向聡 (20359798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 松浦正明 (40173794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 森田智視 (60362480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 大東智洋 (90980863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Sozu Takashi 寒水 孝司

Takashi Sozu 寒水 孝司

SOZU Takashi 寒水 孝司

Research Projects

Research Products

Co-Researchers

Evaluation and construction of the Bayesian method to accelerate drug developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

A statistical method for achieving efficient and rapid clinical trialsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A study design for achieving efficient and rapid clinical trialsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Statistical frameworks for efficient decision-making in complex clinical trial designs

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

A new clinical trial design considering the efficiency of multiple primary endpointsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Design and statistical analysis in translational clinical trials

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Statistical Issues in Complex Medical Product Development

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Design and Analysis of Clinical Trials with Multiple Co-primary EndpointsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Statistical Methodologies for Improving Predictability in Clinical Research and Development of Drugs

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

[Book] Sample Size Determination in Clinical Trials with Multiple Primary Endpoints2015

Author(s)

Publisher

Data Source

[Journal Article] Copula-Based Model for Incorporating Single-Agent Historical Data into Dual-Agent Phase I Cancer Trials2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Using horseshoe prior for incorporating multiple historical control data in randomized controlled trials2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Predicting study duration in clinical trials with a time-to-event endpoint2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sizing clinical trials when comparing bivariate time-to-event outcomes2017

Sozu Takashi 寒水孝司

Takashi Sozu 寒水孝司

SOZU Takashi 寒水孝司