KAWASE Atsushi 川瀬篤史

… Alternative Names

川瀬篤史カワセアツシ

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Researcher Number	80411578
Other IDs
Affiliation (Current)	2025: 近畿大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2023: 近畿大学, 薬学部, 准教授 2011 – 2017: 近畿大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Medical pharmacy Except Principal Investigator Medical pharmacy
Keywords	Principal Investigator 裏打ちタンパク質 / トランスポーター / radixin / 抗がん薬 / ERMタンパク質 / P-糖タンパク質 / サイトカイン / 炎症 / デリバリー / ペプチド … More / 多剤耐性 / 抗がん剤 / がん細胞 / 足場タンパク質 / ABCB / ABCC / P-glycoprotein / MRP / プロテオーム / 生体分子 / 薬学 / MRP2 / リン酸化 / 肝細胞 / 胆汁排泄 / 肝臓 / 一酸化窒素 … More Except Principal Investigator 反応性代謝物 / 肝毒性 / グルタチオン / ミクロソーム / アシルCoAチオエステル体 / 特異体質性肝障害 / CoAチオエステル体 / NSAIDs / マクロファージ / アシルグルクロン酸抱合体 / アシルCoAチオエステル / 肝障害 / 免疫細胞 / 非ステロイド性抗炎症薬 / 特異体質性肝毒性 / アシルグルクロナイド / siRNA / 代謝酵素 / トランスポーター / 薬物動態・代謝学 Less

Effect of transporter-associated protein-targeting peptides on anticancer drug delivery efficiencyPrincipal Investigator
- Principal Investigator
  
  Kawase Atsushi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kindai University
Modulation of transporter-associated proteins to overcome the anticancer drug resistancePrincipal Investigator
- Principal Investigator
  
  Kawase Atsushi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kindai University
Involvement of acyl-CoA thioester metabolite in drug-induced idiosyncratic liver injury
- Principal Investigator
  
  Iwaki Masahiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kindai University
Effects of inflammatory factors on ERM proteins and transporters functionsPrincipal Investigator
- Principal Investigator
  
  KAWASE Atsushi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kindai University
Relation between ERM protein expression and transporter functions in inflammationPrincipal Investigator
- Principal Investigator
  
  KAWASE Atsushi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kinki University
Involvement of metabolic enzymes and transporters in diclofenac-induced liver injury
- Principal Investigator
  
  IWAKI Masahiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kinki University

All 2023 2022 2021 2020 2019 2018 2016 2014 Other

All Journal Article Presentation

[Journal Article] トランスポーター機能調節ペプチドを利用した抗がん薬デリバリー効率の改善2023
- Author(s)
  川瀬篤史
- Journal Title
  
  月刊細胞
  
  Volume: 55 Pages: 704-705
- Data Source
  KAKENHI-PROJECT-21K06698
[Journal Article] Slc25a39 and Slc25a40 Expression in Mice with Bile Duct Ligation or Lipopolysaccharide Treatment2022
- Author(s)
  Kawase Atsushi、Hatanaka Momoko、Matsuda Naoya、Shimada Hiroaki、Iwaki Masahiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 15 Pages: 8573-8573
- DOI
  10.3390/ijms23158573
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06698
[Journal Article] Stereoselective Covalent Adduct Formation of Acyl Glucuronide Metabolite of Nonsteroidal Anti-Inflammatory Drugs with UDP-Glucuronosyltransferase2022
- Author(s)
  Kawase Atsushi、Yamashita Rio、Yoshizato Tsubasa、Yoshikawa Mashiro、Shimada Hiroaki、Iwaki Masahiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 9 Pages: 4724-4724
- DOI
  10.3390/ijms23094724
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06698
[Journal Article] Changes in Radixin Expression and Interaction with Efflux Transporters in the Liver of Adjuvant-Induced Arthritic Rats2020
- Author(s)
  Kawase Atsushi, Nakasaka Misaki, Bando Hatsune, Yasuda Saori, Shimada Hiroaki, Iwaki Masahiro
- Journal Title
  
  Inflammation
  
  Volume: 43 Issue: 1 Pages: 85-94
- DOI
  10.1007/s10753-019-01097-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06806
[Journal Article] Involvement of diclofenac acyl-β-d-glucuronide in diclofenac-induced cytotoxicity in glutathione-depleted isolated murine hepatocytes co-cultured with peritoneal macrophages2019
- Author(s)
  Kawase Atsushi、Kaneto Ayaka、Ishibashi Mao、Kobayashi Akihiro、Shimada Hiroaki、Iwaki Masahiro
- Journal Title
  
  Toxicology Mechanisms and Methods
  
  Volume: 29 Issue: 3 Pages: 203-210
- DOI
  10.1080/15376516.2018.1544384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08432
[Journal Article] Decrease in Multidrug Resistance-associated Protein 2 Activities by Knockdown of Phosphatidylinositol 4-phosphate 5-kinase in Hepatocytes and Cancer Cells2019
- Author(s)
  Kawase Atsushi、Inoue Yuta、Hirosoko Miho、Sugihara Yuka、Shimada Hiroaki、Iwaki Masahiro
- Journal Title
  
  Journal of Pharmacy & Pharmaceutical Sciences
  
  Volume: 22 Pages: 576-584
- DOI
  10.18433/jpps30444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06806
[Journal Article] Radixin knockdown improves the accumulation and efficiency of methotrexate in tumor cells2019
- Author(s)
  Kawase Atsushi、Inoue Yuta、Nakazaki Sayaka、Koizumi Erika、Iwaki Masahiro
- Journal Title
  
  Oncology Reports
  
  Volume: 42 Pages: 283-290
- DOI
  10.3892/or.2019.7162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06806
[Journal Article] Decreased radixin function for ABC transporters in liver in adjuvant-induced arthritis rats.2014
- Author(s)
  Kawase A, Sakata M, Yada N, Nakasaka M, Shimizu T, Kato Y, Iwaki M.
- Journal Title
  
  J Pharm Sci
  
  Volume: 103 Issue: 12 Pages: 4058-4065
- DOI
  10.1002/jps.24210
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390040, KAKENHI-PROJECT-26860119
[Journal Article] Distinct Alterations in ABC Transporter Expression in Liver, Kidney, Small Intestine, and Brain in Adjuvant-induced Arthritic Rats.2014
- Author(s)
  Kawase A, Norikane S, Okada A, Adachi M, Kato Y, Iwaki M.
- Journal Title
  
  J Pharm Sci
  
  Volume: 103 Issue: 8 Pages: 2556-2564
- DOI
  10.1002/jps.24043
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390040, KAKENHI-PROJECT-26860119
[Presentation] 炎症モデルマウスにおけるグルタチオン輸送トランスポーターSlc25a39/40発現および機能変動2022
- Author(s)
  川瀬篤史，畑中もも子，松田尚也，首藤礼華，島田紘明，岩城正宏
- Organizer
  第49回日本毒性学会
- Data Source
  KAKENHI-PROJECT-21K06698
[Presentation] NHERF1/EBP50を標的とした排出トランスポーターの機能調節2021
- Author(s)
  川瀬篤史，小山勇之介，深江彩加，首藤礼華，島田紘明，岩城正宏
- Organizer
  第71回日本薬学会関西支部
- Data Source
  KAKENHI-PROJECT-21K06698
[Presentation] In situ肝還流法によるジクロフェナクの肝毒性評価2020
- Author(s)
  清水佑里子、島田紘明、藤原麻由、川瀬篤史、岩城正宏
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08432
[Presentation] 肝細胞とマクロファージの共培養系を用いたジクロフェナク誘発性細胞傷害の評価2020
- Author(s)
  山下莉央、川瀬篤史、高島桜花、吉里翼、島田紘明、岩城正宏
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08432
[Presentation] ジクロフェナクのグルクロン酸抱合に与えるCa2+およびMg2+の影響2019
- Author(s)
  清水佑里子，島田紘明，濵口健斗，川瀬篤史，岩城正宏
- Organizer
  未来創薬医療イノベーションシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08432
[Presentation] 非ステロイド性抗炎症薬のアシルグルクロン酸抱合体の生成・分解パラメータによる毒性予測の可能性2019
- Author(s)
  熊澤佳亮、島田紘明、野見真人、塩尻眞弓、川瀬篤史、岩城正宏
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-17K08432
[Presentation] 非ステロイド性抗炎症薬のアシルグルクロン酸抱合体生成に対するCa2+およびMg2+の促進作用2019
- Author(s)
  島田紘明、清水佑里子、濵口健斗、藤本和佳、川瀬篤史、岩城正宏
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-17K08432
[Presentation] 肝ミクロソーム中におけるアシルグルクロン酸抱合体の生成・分解パラメータによる毒性評価の可能性2019
- Author(s)
  島田紘明、熊澤佳亮、野見真人、塩尻真弓、生田博之、川瀬篤史、岩城正宏
- Organizer
  日本薬物動態学会第34年会
- Data Source
  KAKENHI-PROJECT-17K08432
[Presentation] Modulation of transporter activities in cancer cells by transporter-associated proteins2018
- Author(s)
  Kawase Atsushi, Inoue Yuta, Hirosoko Miho, Shimada Hiroaki, Iwaki Masahiro
- Organizer
  2018 MDO/JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06806
[Presentation] Impact of Ca2+ and Mg2+ depletion on glucuronidation of diclofenac2018
- Author(s)
  Hiroaki Shimada, Kento Hamaguchi, Yuriko Shimizu, Atsushi kawase, Masahiro Iwaki
- Organizer
  2018 International Meeting on 22th MDO and 33rd JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08432
[Presentation] 抗がん薬デリバリー効率の改善を目指して～トランスポーター裏打ちタンパク質の調節を利用したトランスポーター発現低下への試み～2018
- Author(s)
  廣底美保，川瀬篤史，井上裕太，杉原由華，小山勇之介，島田紘明，岩城正宏
- Organizer
  未来創薬医療イノベーションシンポジウム
- Data Source
  KAKENHI-PROJECT-18K06806
[Presentation] トランスポーター裏打ちタンパク質を利用した抗がん薬デリバリー効率の改善2018
- Author(s)
  川瀬篤史，井上裕太，廣底美保，杉原由華，島田紘明，岩城正宏
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K06806
[Presentation] Modulation of transporter activities in hepatocytes and cancer cells by knockdown of transporter-associated proteins2018
- Author(s)
  Kawase Atsushi
- Organizer
  The 2nd Workshop for Korea-Japan Young Scientists on Pharmaceutics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06806
[Presentation] 非ステロイド性抗炎症薬のアシルグルクロン酸抱合体生成に対するCa2+およびMg2+の影響2018
- Author(s)
  島田紘明，濵口健斗，清水佑里子，藤本和佳，川瀬篤史，岩城正宏
- Organizer
  第68回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-17K08432
[Presentation] Effect of ERM protein function depression on ABC transporter activities2016
- Author(s)
  井上裕太，川瀬篤史，中崎紗也香，小泉栄里香，島田紘明，岩城正宏
- Organizer
  日本薬物動態学会第31回年会
- Place of Presentation
  キッセイ文化ホール（長野）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K18966
[Presentation] Influence of radixin knockdown on drug efflux transporters of cancer cells2016
- Author(s)
  井上裕太，川瀬篤史，中崎紗也香，小泉栄里香，島田紘明，岩城正宏
- Organizer
  第12回プロテインホスファターゼ国際カンファレンス
- Place of Presentation
  近畿大学（大阪）
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18966
[Presentation] Alterations in expression and function of ABC transporters and ERM proteins in inflammation2014
- Author(s)
  Kawase A
- Organizer
  Global Education Seminar West 2014-1st, Academy of Pharmaceutical Science and Technology, Japan
- Place of Presentation
  Kyoto University (Kyoto, Kyoto)
- Year and Date
  2014-12-12
- Invited
- Data Source
  KAKENHI-PROJECT-26860119
[Presentation] 炎症時におけるトランスポーター変動とERMタンパク質の関連2014
- Author(s)
  川瀬篤史
- Organizer
  第64回日本薬学会近畿支部総会・大会
- Place of Presentation
  京都薬科大学（京都府京都市）
- Year and Date
  2014-10-11
- Invited
- Data Source
  KAKENHI-PROJECT-26860119
[Presentation] Alterations in expression and function of ABC transporters and ERM proteins in adjuvant-induced arthritis rats2014
- Author(s)
  Kawase A, Iwaki M
- Organizer
  Anti-Aging International Mini-Symposium 2014 Cell Signaling and Therapeutic Targets for Geriatric and Inflammatory Diseases
- Place of Presentation
  Kinki University (Higashi-osaka, Osaka)
- Year and Date
  2014-06-07
- Invited
- Data Source
  KAKENHI-PROJECT-26860119
[Presentation] Alterations in expression and function of ezrin/radixin/moesin proteins for transporters in adjuvant-induced arthritis rats
- Author(s)
  Iwaki M, Kawase A, Sakata M, Nakasaka M, Kato Y
- Organizer
  19th North American Regional ISSX Meeting and 29th JSSX Meeting
- Place of Presentation
  Hilton San Francisco (San Francisco, USA)
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-26860119

1. IWAKI Masahiro (30140346)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. 山下哲生 (80444727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 島田紘明 (40783444)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. 加藤将夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

KAWASE Atsushi 川瀬 篤史

川瀬 篤史 カワセ アツシ

Research Projects

Research Products

Co-Researchers

Effect of transporter-associated protein-targeting peptides on anticancer drug delivery efficiencyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Modulation of transporter-associated proteins to overcome the anticancer drug resistancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Involvement of acyl-CoA thioester metabolite in drug-induced idiosyncratic liver injury

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of inflammatory factors on ERM proteins and transporters functionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Relation between ERM protein expression and transporter functions in inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of metabolic enzymes and transporters in diclofenac-induced liver injury

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] トランスポーター機能調節ペプチドを利用した抗がん薬デリバリー効率の改善2023

Author(s)

Journal Title

Data Source

[Journal Article] Slc25a39 and Slc25a40 Expression in Mice with Bile Duct Ligation or Lipopolysaccharide Treatment2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stereoselective Covalent Adduct Formation of Acyl Glucuronide Metabolite of Nonsteroidal Anti-Inflammatory Drugs with UDP-Glucuronosyltransferase2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Changes in Radixin Expression and Interaction with Efflux Transporters in the Liver of Adjuvant-Induced Arthritic Rats2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Involvement of diclofenac acyl-β-d-glucuronide in diclofenac-induced cytotoxicity in glutathione-depleted isolated murine hepatocytes co-cultured with peritoneal macrophages2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Decrease in Multidrug Resistance-associated Protein 2 Activities by Knockdown of Phosphatidylinositol 4-phosphate 5-kinase in Hepatocytes and Cancer Cells2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Radixin knockdown improves the accumulation and efficiency of methotrexate in tumor cells2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Decreased radixin function for ABC transporters in liver in adjuvant-induced arthritis rats.2014

Author(s)

Journal Title

DOI

Data Source

KAWASE Atsushi 川瀬篤史

川瀬篤史カワセアツシ

[Presentation] 抗がん薬デリバリー効率の改善を目指して～トランスポーター裏打ちタンパク質の調節を利用したトランスポーター発現低下への試み～2018