NAKAGOMI Hiroshi 中込宙史

Researcher Number	80418714
Affiliation (based on the past Project Information) *help	2017: 山梨大学, 大学院総合研究部, 助教 2016: 山梨大学, 総合研究部, 助教 2013: 山梨大学, 医学工学総合研究部, 助教 2012 – 2013: 山梨大学, 医学部附属病院, 助教 2011: 山梨大学, 医学部附属病院, 診療助教 2010: 山梨大学, 医学部・附属病院, 医員
Review Section/Research Field	Principal Investigator Urology Except Principal Investigator Urology
Keywords	Principal Investigator 排尿機能学 / ｃAMP / 閉塞膀胱 / 膀胱上皮 / Epac / 国際情報交流 / 国際情報交換 / 神経科学 / 生理学 / シグナル伝達 … More Except Principal Investigator … More Piezo1 / メカノセンサー / ATP / 膀胱 / 尿路上皮 / VNUT / 国際情報交換 / piezo1 / 機械受容体 / 夜間頻尿 / 過活動膀胱 / 時計遺伝子 / 多国籍 / 国際情報交流 / ペインコントロール / 附子 / 漢方 / 慢性疼痛症候群 / 神経障害性疼痛 / ボツリヌス毒素 / トリカブト / 附子（トリカブト） / ボツリヌストキシン / 漢方治療 / 間質性膀胱炎 / 蓄尿障害 / 求心性シグナル伝達 / TRPV4 / ＴＲＰＶ４ / TRPV４ / 膀胱上皮 / P2Y6 / PIEZO / TRP / イオンチャネル / Overactive bladder / Urinary bladder / Afferent nerve / 末梢神経障害 / 脊髄損傷 / 外尿道括約筋 / 下部尿路機能 / 神経障害 / 切迫性尿失禁 / 尿意切迫感 / 反射排尿 / 残尿 / 排尿収縮圧 / 膀胱コンプライアンス / 神経ペプチド / 脊髄 / 下部尿路障害 / 低活動膀胱 / マウス / 脳下垂体アデニル酸シクラーゼ活性化ポリペプチド(PACAP) / 糖尿病 / 尿道 / 排尿障害 Less

Elucidation of the role of bladder epithelial Epac in the condition of the obstructed bladderPrincipal Investigator
- Principal Investigator
  
  NAKAGOMI Hiroshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
The mechanosensor Piezo1 is expressed in the urothelium and has a crucial function in the urine storage phase in the bladder.
- Principal Investigator
  
  MIYAMOTO Tatsuya
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
Research on the afferent transduction in the lower urinary tract
- Principal Investigator
  
  TAKEDA Masayuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
Involvements of TRPV1 and TRPV4 channels in regulatory function to maintain bladder stability during urine storage: integrated analysis of behavior and reflex
- Principal Investigator
  
  MOCHIZUKI Tsutomu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
The mechanism of action of aconite and botulinum toxin for interstitial cystitis pain
- Principal Investigator
  
  TSUCHIDA Takayuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
Mechanisms And Possible Novel Treatments for Nocturiarelated to Abnormal Circadian Rhythm
- Principal Investigator
  
  TAKEDA Masayuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
The elucidation of ATP releasing pathway of bladder epithelial cell upon stretch stimulationPrincipal Investigator
- Principal Investigator
  
  NAKAGOMI Hiroshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
Strategy targeting neuropeptide receptors in the central and peripheral nervous systems in treatment of underactive bladder
- Principal Investigator
  
  YOSHIYAMA Mitsuharu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi

All 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book Patent

[Book] 排尿障害プラクティス2012
- Author(s)
  中込宙史、望月勉、武田正之
- Total Pages
  8
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-23592361
[Journal Article] Functional role for Piezo1 in stretch-evoked Ca2+ influx and ATP release in urothelial cell cultures2014
- Author(s)
  Tatsuya Miyamoto, Tsutomu Mochizuki, Hiroshi Nakagomi, Satoru Kira, Masaki Watanabe, Yasunori Takayama, Yoshiro Suzuki, Schuichi Koizumi, Masayuki Takeda and MakotoTominaga
- Journal Title
  
  J Biol Chem
  
  Volume: (Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-23592361
[Journal Article] Functional role for Piezo1 in stretch-evoked Ca 2+ influx and ATP release in urothelial cell cultures.2014
- Author(s)
  Miyamoto T, Mochizuki T, Nakagomi H, Kira S, Watanabe M, Takayama Y, Suzuki Y, Koizumi S, Takeda M, Tominaga M.
- Journal Title
  
  J Biol Chem.
  
  Volume: 53 Pages: 1230-1238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592361
[Journal Article] 医薬ジャーナル2013
- Author(s)
  武田正之、荒木勇雄、澤田智史、中込宙史、望月勉、小林英樹、座光寺秀典、芳山充晴
- Journal Title
  
  新薬展望 2013
  
  Volume: Vol. 49
- Data Source
  KAKENHI-PROJECT-23791749
[Journal Article] 医薬ジャーナル2013
- Author(s)
  武田正之、荒木勇雄、澤田智史、中込宙史、望月勉、小林英樹、座光寺秀典、芳山充晴
- Journal Title
  
  新薬展望2013
  
  Volume: Vol.49 S-1
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] 膀胱上皮におけるTRPVチャネルとATP放出メカニズム2013
- Author(s)
  中込宙史、望月勉、武田正之
- Journal Title
  
  膀胱上皮におけるTRPVチャネルとATP放出メカニズム
  
  Volume: vol.20 Pages: 7-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592361
[Journal Article] 膀胱上皮におけるTRPVチャネルとATP放出メカニズム2012
- Author(s)
  中込宙史、望月勉、武田正之
- Journal Title
  
  排尿障害プラクティス
  
  Volume: vol.20, No.1 Pages: 7-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592361
[Journal Article] 排尿障害におけるβ3 受容体刺激(作動)薬2012
- Author(s)
  武田正之、中込宙史、芳山充晴、荒木勇雄
- Journal Title
  
  診断と治療
  
  Volume: 第100巻・第8号 Pages: 1379-1385
- Data Source
  KAKENHI-PROJECT-23791749
[Journal Article] 排尿障害におけるβ3受容体刺激(作動)薬2012
- Author(s)
  武田正之、中込宙史、芳山充晴、荒木勇雄
- Journal Title
  
  診断と治療
  
  Volume: 第100巻・第8号 Pages: 1379-1385
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] 排尿障害におけるβ3 受容体作動薬2012
- Author(s)
  武田正之、中込宙史、芳山充晴、荒木勇雄
- Journal Title
  
  Progress in Medicine
  
  Volume: Vol. 32 (No. 4) Pages: 37-42
- Data Source
  KAKENHI-PROJECT-23791749
[Journal Article] 排尿障害におけるβ3受容体作動薬2012
- Author(s)
  武田正之、中込宙史、芳山充晴、荒木勇雄
- Journal Title
  
  Progress in Medicine
  
  Volume: Vol.32 (No.4) Pages: 37-42
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] 第4回国際尿失禁会議からの報告 Committee3 Cell Biology 「細胞生物学」2011
- Author(s)
  武田正之、中込宙史、宮本達也、吉良聡、芳山充晴
- Journal Title
  
  排尿障害プラクティス
  
  Volume: Vol.19(1) Pages: 66-88
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] 第4回国際尿失禁会議からの報告2011
- Author(s)
  武田正之、中込宙史、宮本達也、吉良聡、芳山充晴
- Journal Title
  
  Committee3 Cell Biology 「細胞生物学」.排尿障害プラクティス
  
  Volume: Vol.19(1) Pages: 66-88
- Data Source
  KAKENHI-PROJECT-23791749
[Journal Article] VNUT(Vesicular Nucleotide Transporter)を介する膀胱上皮からのATP放出メカニズム2011
- Author(s)
  中込宙史、望月勉、芳山充晴、宮本達也吉良聡、川原和也、荒木勇雄、小泉修一森山芳則、武田正之
- Journal Title
  
  日本排尿機能学会誌
  
  Volume: Vol.22(1) Pages: 121-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592361
[Journal Article] Decreased Expression of the Epithelial Ca2+ Channel TRPV5 and TRPV6 in Human Renal Cell Carcinoma: Associated with Vitamin D Receptor2011
- Author(s)
  Yongyang Wu, Tatsuya Miyamoto, Kai Li, Hiroshi Nakagomi, Norifumi Sawada, Satoru Kira, Hideki Kobayashi, Hidenori Zakoji, Takayuki Tsuchida, Mizuya Fukazawa, Isao Araki, Masayuki Takeda
- Journal Title
  
  J. Urol
  
  Volume: 186 Pages: 2419-2425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659754
[Journal Article] Sensor mechanism and afferent signal transduction of the urinary bladder: special focus on transient receptor potential ion channels2010
- Author(s)
  Takeda M, Mochizuki T, Yoshiyama M, Nakagomi H, Kobayashi H, Sawada N, Zakohji H, Du S, Araki I
- Journal Title
  
  LUTS (Lower Urinary Tract Symptoms)
  
  Volume: 2 Pages: 51-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] 尿路上皮と排尿2010
- Author(s)
  荒木勇雄、中込宙史、望月勉、小林英樹、芳山充晴、武田正之
- Journal Title
  
  臨床検査
  
  Volume: Vol.54(7) Pages: 726-730
- Data Source
  KAKENHI-PROJECT-22591787
[Journal Article] Sensor mechanism and afferent signal transduction of the urinary bladder: special focus on transient receptor potential ion channels2010
- Author(s)
  Takeda M, Mochizuki T, Yoshiyama M, Nakagomi H, Kobayashi H, Sawada N, Zakohji H, Du S, Araki I
- Journal Title
  
  LUTS (Lower Urinary Tract Symptoms)
  
  Volume: 2 Pages: 51-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791749
[Journal Article] 尿路上皮と排尿2010
- Author(s)
  荒木勇雄、中込宙史、望月勉、小林英樹、芳山充晴、武田正之
- Journal Title
  
  臨床検査
  
  Volume: Vol.54(7) Pages: 726-730
- Data Source
  KAKENHI-PROJECT-23791749
[Patent] 新規頻尿治療薬としての GsMTX4の効果2012
- Inventor(s)
  宮本達也, 武田正之, 小泉修一, 中込宙史
- Industrial Property Rights Holder
  国立大学法人山梨大学
- Industrial Property Rights Type
  特許
- Filing Date
  2012-10-19
- Data Source
  KAKENHI-PROJECT-23390381
[Presentation] VNUT plays a crucial role in stretch-evoked ATP releasefrom urothelium2013
- Author(s)
  中込　宙史
- Organizer
  アメリカ泌尿器科学会
- Place of Presentation
  Georgia World Congress Center(Atlanta USA)
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] ヒト膀胱上皮における VNUT m-RNA発現量と各種排尿パラメータとの関連性2013
- Author(s)
  中込　宙史
- Organizer
  日本泌尿器科学会総会
- Place of Presentation
  さっぽろ芸術文化の館（北海道）
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] VNUT (vesicular nucleotide transporter) plays a crucial role in stretch-evoked ATP release from urothelium2012
- Author(s)
  Nakagomi H, Mochizuki T, Miyamoto T, Yoshiyama M, Araki I, Moriyama Y, Koizumi S, Takeda M
- Organizer
  (Abstract No. 495, May 20, 2012) American Urological Association Annual Meeting, Georgia World Congress Center
- Place of Presentation
  Atlanta, Georgia, U.S.A
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] Evaluation of increased voiding frequency in mice with type 2 diabetes mellitus2012
- Author(s)
  Yoshiyama M, Mochizuki T, Nakagomi H, Miyamoto T, Takeda M
- Organizer
  American Urological Association Annual Meeting, Georgia World Congress Center
- Place of Presentation
  Atlanta, Georgia, U.S.A.
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] 代謝型グルタミン酸受容体サブタイプ5を介する神経伝達の遮断は膀胱収縮性及び排尿を損ねずに蓄尿を促す2012
- Author(s)
  芳山充晴、土屋幸子、望月勉、中込宙史、宮本達也、吉良聡、武田正之
- Organizer
  第19回日本排尿機能学会
- Place of Presentation
  愛知県名古屋市
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Vesicular nucleotide transporter (VNUT) is a key molecule for mechanosensing in the human urinary bladder: negative correlation between VNUT expression in human bladder mucosa and first desire to void. (Abstract No. 12)2012
- Author(s)
  Nakagomi H, Mochizuki T, Miyamoto T, Kira S, Yoshiyama M, Kawahara K, Moriyama Y, Koizumi S, Takeda M.
- Organizer
  International Continence Society 42nd Annual meeting, China National Convention Centre
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] (vesicular nucleotide transporter) plays a crucial role in stretch-evoked ATP release from urothelium.2012
- Author(s)
  Nakagomi H, Mochizuki T, Miyamoto T, Yoshiyama M, Araki I, Moriyama Y, Koizumi S, Takeda M.
- Organizer
  American Urological Association Annual Meeting, Georgia World Congress Center
- Place of Presentation
  Atlanta, Georgia, U.S.A.
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Significant correlation between Vitamine D receptor and epithelial Ca2+ ion channel TRPV5 and TRPV6 in renal cell carcinoma2012
- Author(s)
  Wu Yongyang, Tatsuya Miyamoto , Li Kai , Hiroshi Nakagomi, Norifumi Sawada, Satoru Kira, Hideki Kobayashi , Hidenori Zakoji, Isao Araki , Masayuki Takeda
- Organizer
  The 107th Annual Meeting of The American Urological Association
- Place of Presentation
  Atlanta, USA
- Year and Date
  2012-05-20
- Data Source
  KAKENHI-PROJECT-23659754
[Presentation] 代謝型グルタミン酸受容体サブタイプ5 を介する神経伝達の遮断は膀胱収縮性及び排尿を損ねずに蓄尿を促す2012
- Author(s)
  芳山充晴、土屋幸子、望月勉、中込宙史、宮本達也、吉良聡、武田正之
- Organizer
  第19回日本排尿機能学会
- Place of Presentation
  愛知県名古屋市・名古屋国際会議場
- Year and Date
  2012-08-30
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] Evaluation of increased voiding frequency in mice with type 2 diabetes mellitus2012
- Author(s)
  Yoshiyama M, Mochizuki T, Nakagomi H, Miyamoto T, Takeda M
- Organizer
  (Abstract No. 256, May 20, 2012) American Urological Association Annual Meeting
- Place of Presentation
  Georgia World Congress Center, Atlanta, Georgia, U.S.A.
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] Vesicular nucleotide transporter (VNUT) is a key molecule for mechanosensing in the human urinary bladder: negative correlation between VNUT expression in human bladder mucosa and first desire to void2012
- Author(s)
  Nakagomi H, Mochizuki T, Miyamoto T, Kira S, Yoshiyama M, Kawahara K, Moriyama Y, Koizumi S, Takeda M
- Organizer
  (Abstract No. 12) International Continence Society 42nd Annual meeting, China National Convention Centre
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] Evaluation of increased voiding frequency in mice with type 2 diabetes mellitus2012
- Author(s)
  Mitsuharu Yoshiyama, Tsutomu Mochizuki , Hiroshi Nakagomi, Tatsuya Miyamoto, Masayuki Takeda
- Organizer
  The 107th Annual Meeting of The American Urological Association
- Place of Presentation
  Atlanta, USA
- Year and Date
  2012-05-21
- Data Source
  KAKENHI-PROJECT-23659754
[Presentation] 伸展刺激時の膀胱上皮からのATP放出機構におけるVNUT／開口放出経路の解析2012
- Author(s)
  中込　宙史
- Organizer
  日本泌尿器科学会総会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] 伸展刺激に対する膀胱上皮細胞からのＡＴＰ放出メカニズム2012
- Author(s)
  中込宙史
- Organizer
  第85回日本薬理学会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] VNUT(Vesivularnucleotide transporter) plays a crucial role in atretch-evoked ATP release from the urothelium2012
- Author(s)
  Hiroshi Nakagomi, Tsutomu Mochizuki , Tatsuya Miyamoto, Mitsuharu Yoshiyama , Isao Araki, Yoshinori Moriyama, Schuichi Koizumi, Masayuki Takeda
- Organizer
  The 107th Annual Meeting of The American Urological Association
- Place of Presentation
  Atlanta, USA
- Year and Date
  2012-05-20
- Data Source
  KAKENHI-PROJECT-23659754
[Presentation] VNUT(Vesicular Nucleotide Transporter)を介する膀胱上皮からのATP放出メカニズムの解明2011
- Author(s)
  中込宙史
- Organizer
  第18回日本排尿機能学会
- Place of Presentation
  福井フェニックスプラザ（福井）
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] VNUT plays an important role in vesicular storage and subsequent exocytosis of ATP from bladder epithelium upon mechanical stretch stimulation2011
- Author(s)
  中込宙史
- Organizer
  日本泌尿器科学会総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23592362
[Presentation] 膀胱上皮細胞の伸展刺激に対するＡＴＰ放出メカニズムの解明2011
- Author(s)
  中込宙史
- Organizer
  第99回日本泌尿器科学会総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] 遺伝性発症2 型糖尿病マウスの若年期における頻尿の病態解析2011
- Author(s)
  芳山充晴,望月勉,中込宙史,宮本達也,武田正之
- Organizer
  第18回日本排尿機能学会
- Place of Presentation
  福井県福井市
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] Evalutations of increased voiding frequency in mice with diabetes mellitus at early stage.2011
- Author(s)
  Yoshiyama M, Mochizuki T, Nakagomi H, Miyamoto T, Kobayashi H, Zakoji H, Takeda M.
- Organizer
  International Continence Society Meeting 41st
- Place of Presentation
  Glasgow, U.K
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Comparisons between voluntary behaviour and reflex response in control of the lower urinary tract function of mice.2011
- Author(s)
  Yoshiyama M, Mochizuki T, Nakagomi H, Kobayashi H, Miyamoto T, Zakoji H, Takeda M.
- Organizer
  International Continence Society Meeting 41st
- Place of Presentation
  Glasgow, U.K
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] VNUT (Vesicular Nucleotide Transporter) を介する膀胱上皮からの ATP 放出メカニズムの解明2011
- Author(s)
  中込宙史,望月勉,芳山充晴,宮本達也,吉良聡,川原和也,荒木勇雄,小泉修一,森山芳則,武田正之
- Organizer
  第18回日本排尿機能学会
- Place of Presentation
  福井県福井市
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] VNUT PLAYS AN IMPORTANT ROLE IN VESICULAR STORAGE AND SUBSEQUENT EXOCYTOSIS OF ATP FROM BLADDER EPITHELIUM UPON MECHANICAL STRETCH STIMULATION2011
- Author(s)
  中込宙史
- Organizer
  41st ANNUAL MEETING OF THE INTERNATIONAL CONTINENCE SOCIETY (ICS)
- Place of Presentation
  Scotish Exhibition&conference Center（Glasgow,UK）
- Data Source
  KAKENHI-PROJECT-23592362
[Presentation] VNUT PLAYS AN IMPORTANT ROLE IN VESICULAR STORAGE AND SUBSEQUENT EXOCYTOSIS OF ATP FROM BLADDER EPITHELIUM UPON MECHANICAL STRETCH STIMULATION2011
- Author(s)
  Hiroshi Nakagomi
- Organizer
  41st ANNUAL MEETING OF THE INTERNATIONAL CONTINENCE SOCIETY (ICS)
- Place of Presentation
  ScotishiExhibition&conference Center（Glasgow,UK）
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] 新規のマウス用排尿代謝ケージ構築ならびに各種パラメーターについて～野生型マウスとTRPV4 ノックアウトマウスとの比較～2011
- Author(s)
  望月勉,中込宙史,芳山充晴,高山靖規,富永真琴,水町凉治,武田正之
- Organizer
  第18回日本排尿機能学会
- Place of Presentation
  福井県福井市
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] Evalutations of increased voiding frequency in mice with diabetes mellitus at early stage2011
- Author(s)
  Yoshiyama M, Mochizuki T, Nakagomi H, Miyamoto T, Kobayashi H, Zakoji H, Takeda M
- Organizer
  (Abstract No. 182) International Continence Society Meeting 41st
- Place of Presentation
  Glasgow, U.K.
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] Comparisons between voluntary behaviour and reflex response in control of the lower urinary tract function of mice2011
- Author(s)
  Yoshiyama M, Mochizuki T, Nakagomi H, Kobayashi H, Miyamoto T, Zakoji H, Takeda M
- Organizer
  (Abstract No. 453) International Continence Society Meeting 41st
- Place of Presentation
  Glasgow, U.K.
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] VNUT plays an important role in vesicular storage and subsequent exocytosis of ATP from bladder epithelium upon mechanical stretch stimulation.2011
- Author(s)
  Nakagomi H, Mochizuki T, Miyamoto T, Kira S, Yoshiyama M, Araki I, Koizumi S, Moriyama Y, Takeda M
- Organizer
  International Continence Society Meeting 41st
- Place of Presentation
  Glasgow, U.K
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] VNUT plays an important role in vesicular storage and subsequent exocytosis of ATP from bladder epithelium upon mechanical stretch stimulation2011
- Author(s)
  Nakagomi H, Mochizuki T, Miyamoto T, Kira S, Yoshiyama M, Araki I, Koizumi S, Moriyama Y, Takeda M
- Organizer
  (Abstract No. 278) International Continence Society Meeting 41st
- Place of Presentation
  Glasgow, U.K.
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] VNUT plays an important role in vesicular storage and subsequent exocytosis of ATP from bladder epithelium upon mechanical stretch stimulation2011
- Author(s)
  Nakagomi, H., et al
- Organizer
  International Continence Society 41^<st> Annual Meeting
- Place of Presentation
  ScotishExhibition&conference Center (Glasgow, U.K.)
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Risk factors of nocturia and assessment of nocturia-related quality of life in Japanese population.2011
- Author(s)
  Imamura N, Yoda Y, Nakagomi H, Miyamoto T, Tsuchida T, Fukazawa M, Araki I, Yoshiyama M, Takeda M.
- Organizer
  International Continence Society Meeting 41st
- Place of Presentation
  Glasgow, U.K
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Risk factors of nocturia and assessment of nocturia-related quality of life in Japanese population2011
- Author(s)
  Imamura N, Yoda Y, Nakagomi H, Miyamoto T, Tsuchida T, Fukazawa M, Araki I, Yoshiyama M, Takeda M
- Organizer
  (Abstract No. 375) International Continence Society Meeting 41st
- Place of Presentation
  Glasgow, U.K.
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] TRPV4-deficient mice exhibit increased frequency of voiding ~evaluation of micturition behaviour using novel metabolic cage system~.2011
- Author(s)
  Mochizuki T, Yoshiyama M, Nakagomi H, Miyamoto T, Takeda M
- Organizer
  International Continence Society Meeting 41st
- Place of Presentation
  Glasgow, U.K
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] 膀胱上皮のＴＲＰＶチャネルとＡＴＰ放出メカニズム2011
- Author(s)
  中込宙史
- Organizer
  第99回日本泌尿器科学会総会(招待講演)
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] TRPV4-deficient mice exhibit increased frequency of voiding ~evaluation of micturition behaviour using novel metabolic cage system2011
- Author(s)
  Mochizuki T, Yoshiyama M, Nakagomi H, Miyamoto T, Takeda M
- Organizer
  (Abstract No. 411) International Continence Society Meeting 41st
- Place of Presentation
  Glasgow, U.K.
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] VNUT (Vesicular Nucleotide Transporter)を介する膀胱上皮からのATP放出メカニズムの解明2011
- Author(s)
  中込宙史, 他
- Organizer
  第18回日本排尿機能学会
- Place of Presentation
  ホテルフジタ福井(福井県福井市)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Hypertension and type 2 diabetes mellitus are highly associated with nocturia than metabolic syndrome in Japanese population.2010
- Author(s)
  Imamura N, Nakagomi H, Yoda Y, Zakoji H, Kobayashi H, Tsuchida T, Fukazawa M, Yoshiyama M, Araki I, Takeda M.
- Organizer
  International Continence Society 40th /International Uro-Gynecology Association Joint Meeting
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] 新規ディバイス排尿用代謝ケージを用いたマウス排尿測定～野生型マウスの各種排尿パラメーターにおける雌雄差について2010
- Author(s)
  望月勉,中込宙史,芳山充晴,水町凉治,武田正之
- Organizer
  第17回日本排尿機能学会
- Place of Presentation
  山梨県甲府市
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] Gene expression patterns of acid-sensing ion channels (ASICs) families in mammalian bladder2010
- Author(s)
  Kobayashi H, Yoshiyama M, Inuzuka H, Kira S, Nakagomi H, Miyamoto T, Haneda Y, Sawada N, Zakoji H, Tsuchida T, Araki I, Takeda M
- Organizer
  (Abstract No. 520) International Continence Society 40th/International Uro-Gynecology Association Joint Meeting
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] Gene expression patterns of acid-sensing ion channels (ASICs) families in mammalian bladder.2010
- Author(s)
  Kobayashi H, Yoshiyama M, Inuzuka H, Kira S, Nakagomi H, Miyamoto T, Haneda Y, Sawada N, Zakoji H, Tsuchida T, Araki I, Takeda M.
- Organizer
  International Continence Society 40th/International Uro-Gynecology Association Joint Meeting
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Hypertension and type 2 diabetes mellitus are highly associated with nocturia than metabolic syndrome in Japanese population2010
- Author(s)
  Imamura N, Nakagomi H, Yoda Y, Zakoji H, Kobayashi H, Tsuchida T, Fukazawa M, Yoshiyama M, Araki I, Takeda M
- Organizer
  (Abstract No. 381) International Continence Society 40th /International Uro-Gynecology Association Joint Meeting
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-23791749
[Presentation] VNUT (vesicular nucleotide transporter) plays a crucial role in stretch-evoked ATP release from urothelium
- Author(s)
  Hiroshi Nakagomi
- Organizer
  American Urological Association Annual Meeting
- Place of Presentation
  Georgia World Congress Center(Atlanta, Georgia, U.S.A.)
- Data Source
  KAKENHI-PROJECT-22591787
[Presentation] Vesicular nucleotide transporter (VNUT) is a key molecule for mechanosensing in the human urinary bladder: negative correlation between VNUT expression in human bladder mucosa and first desire o void
- Author(s)
  Hiroshi Nakagomi
- Organizer
  International Continence Society 42nd Annualmeeting
- Place of Presentation
  China National Convention Centre(Beijing, China)
- Data Source
  KAKENHI-PROJECT-22591787

1. TAKEDA Masayuki (80197318)

# of Collaborated Projects: 5 results

# of Collaborated Products: 10 results
2. YOSHIYAMA Mitsuharu (20422694)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
3. MIYAMOTO Tatsuya (80456459)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. MOCHIDUKI Tsutomu (50377496)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. KOBAYASHI Hideki (50402053)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ZAKOJI Hidenori (60345717)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. SAWADA Norifumi (70402055)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. TOMINAGA Makoto (90260041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KOIZUMI Syuichi (10280752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KIRA Satoru (10530115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TSUCHIDA Takayuki (30217327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 荒木勇雄 (50252424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKAGOMI Hiroshi 中込 宙史

Research Projects

Research Products

Co-Researchers

Elucidation of the role of bladder epithelial Epac in the condition of the obstructed bladderPrincipal Investigator

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The mechanosensor Piezo1 is expressed in the urothelium and has a crucial function in the urine storage phase in the bladder.

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Research on the afferent transduction in the lower urinary tract

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Involvements of TRPV1 and TRPV4 channels in regulatory function to maintain bladder stability during urine storage: integrated analysis of behavior and reflex

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The mechanism of action of aconite and botulinum toxin for interstitial cystitis pain

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Mechanisms And Possible Novel Treatments for Nocturiarelated to Abnormal Circadian Rhythm

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The elucidation of ATP releasing pathway of bladder epithelial cell upon stretch stimulationPrincipal Investigator

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Strategy targeting neuropeptide receptors in the central and peripheral nervous systems in treatment of underactive bladder

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[Book] 排尿障害プラクティス2012

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[Journal Article] Functional role for Piezo1 in stretch-evoked Ca2+ influx and ATP release in urothelial cell cultures2014

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[Journal Article] Functional role for Piezo1 in stretch-evoked Ca 2+ influx and ATP release in urothelial cell cultures.2014

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[Journal Article] 医薬ジャーナル2013

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[Journal Article] 医薬ジャーナル2013

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[Journal Article] 膀胱上皮におけるTRPVチャネルとATP放出メカニズム2013

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Data Source

[Journal Article] 膀胱上皮におけるTRPVチャネルとATP放出メカニズム2012

Author(s)

Journal Title

NAKAGOMI Hiroshi 中込宙史

[Journal Article] 排尿障害におけるβ3 受容体刺激(作動)薬2012