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ISHIKAWA SHINJI  石川 晋之

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ISHIKAWA Shinji  石川 晋之

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Researcher Number 80419639
Other IDs
Affiliation (Current) 2021: 熊本大学, 大学院生命科学研究部(医), 特定研究員
Affiliation (based on the past Project Information) *help 2019: 熊本大学, 病院, 非常勤診療医師
2015 – 2018: 熊本大学, 医学部附属病院, 非常勤診療医師
2007 – 2013: Kumamoto University, 医学部附属病院, 非常勤診療医師
Review Section/Research Field
Principal Investigator
Digestive surgery / Basic Section 55020:Digestive surgery-related
Keywords
Principal Investigator
スタチン / 大腸癌 / HDAC5 / SREBP2 / コレステロール合成経路 / EZH2 / p27 / MEK/ERK / Akt/PKB / 遺伝子 … More / 癌 / シグナル伝達 / 分子標的治療 / ORP5 / コレステロール / 膵癌 / MC1568 / 消化器癌 / K-ras / BRAF / 併用療法 / 相乗効果 / 薬剤耐性 / pERK / pAkt / Elk-1 / statin(スタチン) / 薬物療法 / バイオマーカー / EGFR経路 / Wnt経路 / TGFβ経路 Less
  • Research Projects

    (5 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (19 People)
  •  バイオマーカーに沿ったスタチン併用大腸癌治療法の開発Principal InvestigatorOngoing

    • Principal Investigator
      石川 晋之
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kumamoto University
  •  Elucidation of anti-tumor effect mechanism of statin in colorectal cancer and development of new treatmentPrincipal Investigator

    • Principal Investigator
      ISHIKAWA Shinji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kumamoto University
  •  Clarification of the lipid metabolism concerning progression of gastrointestinal cancer, followed by developing new therapy.Principal Investigator

    • Principal Investigator
      ISHIKAWA Shinji
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kumamoto University
  •  The crosstalk between cholesterol synthesis pathway and TGF-beta in pancreatic cancerPrincipal Investigator

    • Principal Investigator
      ISHIKAWA Shinji
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kumamoto University
  •  Identify the mechanism of invasion and metastasis of pancreatic cancer and development of novel treatment starategy.Principal Investigator

    • Principal Investigator
      ISHIKAWA Shinji
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kumamoto University

All 2019 2018 2014 2013 2010 2008 Other

All Journal Article Presentation

  • [Journal Article] Construction and validation of a simple scoring system for stage III colorectal cancer recurrence (SiS-SCORE). A case control study2019

    • Author(s)
      Ishikawa Shinji、Sawayama Hiroshi、Matsuo Akinobu、Uchino Ryojin、Honda Shinobu、Hirota Masahiko、Baba Hideo
    • Journal Title

      Japanese Journal of Clinical Oncology

      Volume: 49 Pages: 238-244

    • DOI

      10.1093/jjco/hyy192

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10544
  • [Journal Article] Construction and validation of a simple scoring system for stage III colorectal cancer recurrence (SiS-SCORE).2018

    • Author(s)
      Shinji Ishikawa, Hiroshi Sawayama, Akinobu Matsuo, Ryojin Uchino, Shinobu Honda, Masahiko Hirota, Hideo Baba
    • Journal Title

      Annals of Surgical Oncology

      Volume: 査読中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10544
  • [Journal Article] Statins inhibit tumor progression via an enhancer of zeste homolog 2-mediated epigenetic alteration in colorectal cancer2014

    • Author(s)
      S. Ishikawa, H. Hayashi, K. Kinoshita, M. Abe, H. Kuroki, R. Tokunaga, S. Tomiyasu, H. Tanaka, H. Sugita, T. Arita, Y. Yagi, M. Watanabe, M. Hirotaand H. Baba
    • Journal Title

      International Journal of Cancer

      Volume: Epub ahead of print Pages: 2528-36

    • DOI

      10.1002/ijc.28672

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592016, KAKENHI-PROJECT-24591911, KAKENHI-PROJECT-25462062, KAKENHI-PROJECT-25670588
  • [Journal Article] The role of oxysterol bindingprotein related protein 5 inpancreatic cancer2010

    • Author(s)
      Ishikawa S,Nagai Y, Masuda T, Nakamura T,Imamura Y,Takamori H,Hirota M, Funakosi A,Fukushima M,Baba H
    • Journal Title

      Cancer Sci

      Volume: 101 Pages: 898-905

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591525
  • [Journal Article] The role of oxysterol binding protein-related protein 5 in pancreatic cancer2010

    • Author(s)
      Ishikawa S, Nagai Y, Baba H, et al
    • Journal Title

      Cancer Science

      Volume: 101 Pages: 898-905

    • NAID

      10026590764

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591525
  • [Journal Article] The role of Oxyster ol binding protein related protein 5 in pancreatic cancer

    • Author(s)
      Ishikawa S
    • Journal Title

      Cancer Scie nce (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591594
  • [Presentation] StageⅢ大腸癌根治術後再発予測簡易スコアリングシステム(Simple Scoring System for StageⅢ Colorectal cancer Recurrence : SiS-SCORE)の構築と評価2018

    • Author(s)
      石川晋之、澤山 浩、松尾彰章、内野良仁、本田志延、廣田昌彦、馬場秀夫
    • Organizer
      第118回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-16K10544
  • [Presentation] StageⅢ大腸癌根治術後再発予測簡易スコアリングシステム(Simple Scoring System for StageⅢ Colorectal cancer Recurrence : SiS-SCORE)の構築と評価2018

    • Author(s)
      石川晋之、澤山 浩、松尾彰宣、内野良仁、本田志延、廣田昌彦、馬場秀夫
    • Organizer
      第118回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-16K10544
  • [Presentation] 大腸癌high risk StageⅡを考え直す2018

    • Author(s)
      石川晋之、松尾彰宣、内野良仁、本田志延、蔵野良一、廣田昌彦、馬場秀夫
    • Organizer
      第73回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-16K10544
  • [Presentation] 大腸癌術後補助療法としてのスタチンの可能性とそのメカニズム2013

    • Author(s)
      石川晋之
    • Organizer
      第13回日本外科学会定期学術集会
    • Place of Presentation
      マリンメッセ福岡
    • Data Source
      KAKENHI-PROJECT-25462062
  • [Presentation] 大腸癌術後補助療法としてのスタチンの導入2013

    • Author(s)
      石川晋之
    • Organizer
      第68回日本消化器外科学会総会
    • Place of Presentation
      宮崎シーガイアコンベンションセンター
    • Data Source
      KAKENHI-PROJECT-25462062
  • [Presentation] コレステロール合成経路と0RP5 : 膵癌浸潤とスタチンの効果のメカニズム2008

    • Author(s)
      石川 晋之
    • Organizer
      第63回日本消化器外科学会
    • Place of Presentation
      札幌
    • Year and Date
      2008-07-16
    • Data Source
      KAKENHI-PROJECT-19591594
  • [Presentation] コレステロール合成経路とORP5:膵癌浸潤とスタチンの効果のメカニズム2008

    • Author(s)
      石川晋之
    • Organizer
      第63回日本消化器外科学会
    • Place of Presentation
      札幌, ロイトン札幌・札幌プリンスホテル
    • Year and Date
      2008-07-16
    • Data Source
      KAKENHI-PROJECT-19591594
  • [Presentation] 脂質代謝関連遺伝子ORP5と膵臓癌浸潤との関係2008

    • Author(s)
      石川晋之
    • Organizer
      第108回日本外科学会
    • Place of Presentation
      長崎, ベストウェスタンプレミアホテル長崎
    • Year and Date
      2008-05-15
    • Data Source
      KAKENHI-PROJECT-19591594
  • [Presentation] 脂質代謝関連遺伝子0RP5と膵臓癌浸潤との関係2008

    • Author(s)
      石川 晋之
    • Organizer
      第108回日本外科学会
    • Place of Presentation
      長崎
    • Year and Date
      2008-05-15
    • Data Source
      KAKENHI-PROJECT-19591594
  • 1.  TAKAMORI Hiroshi (90363514)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  BABA Hideo (20240905)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 3.  徳永 竜馬 (20594881)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  東 孝暁 (70594878)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  宮本 裕士 (80551259)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  HIROTA Masahiko (80284769)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  HORINO Kei (60452900)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  BEPPU Touru (70301372)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  WATANABE Masayuki (80254639)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  船越 顕博 (80112340)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  林 洋光 (80625773)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  日吉 幸晴 (30573612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  清住 雄希 (30827324)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  宮田 辰徳 (80594887)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  OHUCHI Mayuko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  SUGITA Hiroki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  HAYASHI Naoko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  木下 浩一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  馬場 祥史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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