Nagai Makiko 永井真貴子

… Alternative Names

永井真貴子ナガイマキコ

NAGAI Makiko 永井真貴子

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Researcher Number	80420488
Other IDs
Affiliation (Current)	2025: 北里大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2019 – 2023: 北里大学, 医学部, 講師 2010 – 2015: 北里大学, 医学部, 講師 2009: Okayama University, 大学病院, 助教 2007 – 2008: Okayama University, 医学部・歯学部附属病院, 助教 2005 – 2006: 岡山大学, 医学部・歯学部附属病院, 助手 2005: Okayama University, University Hospital of Medicine and Dentistry, Assistant professor, 医学部歯学部附属病院, 助手
Review Section/Research Field	Principal Investigator Neurology / Basic Section 52020:Neurology-related Except Principal Investigator Neurology / Basic Section 51030:Pathophysiologic neuroscience-related
Keywords	Principal Investigator 筋萎縮性側索硬化症 / 脊髄 / トランスジェニックマウス / アデノ随伴ウィルス / TDP-43 / ALS / 神経変性 / SOD1 / 運動ニューロン / アストロサイト … More / 前頭側頭型認知症 / 海馬 / prion-like propagation / AAV / VachT-Cre / Thy-1 / 運動神経 / Thy-1プロモーター / ＴＤＰ－43 / optineurin / 動物モデル / アデノ随伴ウイルス / 脊髄前角細胞 / マウスモデル / RNA / トランスジェニックウス / オートファジー / レチノイド / 分化誘導 / 胚性幹細胞 / 筋萎縮性側索硬化症(ALS) / Bax / 初代培養 / スーパーオキシドディスムターゼ1 … More Except Principal Investigator IGF-1 / SOD1 / ALS / 筋萎縮性側索硬化症 / SODG93A transgenic mice / FNK / 神経栄養因子 / 髄腔内投与 / トランスジェニックマウス / alpha-synuclein / 腸管神経系 / α-シヌクレイン / 水膜輸送 / 腸管神経 / パーキンソン病 / intrathecal infusion / neurotrophic factors / neural precursor cell / ant-apoptotic therapy / 筋萎縮性側索硬化症(ALS) / 抗アポトーシス治療法 / 再生治療 / 抗アポトーシス治療 / hypoxia / neurotrophic factor / intrathecal administration / transgenic mice / Amyotrophic lateral sclerosis / モデル動物 / EGF / FGF2 / 分化 / 神経幹細胞 / 診断マーカー / 小胞体ストレス / ミトコンドリア / オートファジー / TAT蛋白 / protein transduction domain / TRIAD / 再生療法 / 遺伝子療法 / 蛋白療法 / 神経分子病態学 Less

腸管神経におけるalphaシヌクレインの凝集と水膜輸送の関係
- Principal Investigator
  
  前川達則
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kitasato University
Analysis for prion-like propagation of pathological TDP-43Principal Investigator
- Principal Investigator
  
  Nagai Makiko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kitasato University
The production of newly ALS model micePrincipal Investigator
- Principal Investigator
  
  NAGAI MAKIKO
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kitasato University
Analysis for factors toxic to motor neurons released from astrocytes expressing ALS-linked mutated SOD1.Principal Investigator
- Principal Investigator
  
  NAGAI Makiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kitasato University
  Okayama University
Analysis of the mutated SOD1 astrocyte-releasing factors toxic to motor neuronsPrincipal Investigator
- Principal Investigator
  
  NAGAI Makiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Okayama University
Molecular characterization and gene/regeneration therapy for amyotrophic lateral sclerosis
- Principal Investigator
  
  ABE Koji
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Okayama University
Anti-apoptotic Therapy (Intrathecal Injection of Anti-apoptotic PTD-FNK Protein) in a Mouse Model of Amyotrophic Lateral Sclerosis
- Principal Investigator
  
  TAKEHISA Yasushi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Okayama University
The study for the molecular mechanisms and the newly developed treatment for ALS
- Principal Investigator
  
  ABE Koji
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Okayama University

All 2015 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] パーキンソン病の細胞移植・遺伝子治療2010
- Author(s)
  永井真貴子, 望月秀樹
- Publisher
  Medical Science Disest
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Clinicopathological examination of optineurin-immunoreactive inclusions in patients with sporadic ALS2015
- Author(s)
  Kawanami A, Nagai M, Nihiira T, Ogino M, Nishiyama K.
- Journal Title
  
  The Kitasato Medical Journal
  
  Volume: 45 Pages: 21-28
- NAID
  40020413545
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591275
[Journal Article] Loss of DARPP-32 and calbindin in multiple system atrophy2013
- Author(s)
  Hayakawa H, Nagai M, Kawanami A, Nakata Y, Nihira T, Ogino M, Takada M, Saido T, Takano J, Saegusa M, Mikami T, Hamada J, Nishiyama K, Mochizuki H, Mizuno Y
- Journal Title
  
  Journal of Neural Transmission
  
  Volume: 120 Issue: 12 Pages: 1689-1698
- DOI
  10.1007/s00702-013-1039-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591275, KAKENHI-PUBLICLY-25110716, KAKENHI-PROJECT-25250003, KAKENHI-PROJECT-25640011
[Journal Article] 筋萎縮性側索硬化症の病態解明と治療戦略2012
- Author(s)
  永井真貴子，西山和利
- Journal Title
  
  北里医学
  
  Volume: 42(2) Pages: 85-93
- NAID
  40019551506
- Data Source
  KAKENHI-PROJECT-24591275
[Journal Article] Accumulation of a-synuclein triggered by presynaptic dysfunction2012
- Author(s)
  Nakata Y, Yasuda T, Fukaya M, Yamamori S, Itakura M, Nihira T, Hayakawa H, Kawanami A, Kataoka M, Nagai M, Sakagami H, Takahashi M, Mizuno Y, Mochizuki H
- Journal Title
  
  J. Neurosci
  
  Volume: 32 Issue: 48 Pages: 17186-17196
- DOI
  10.1523/jneurosci.2220-12.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300114, KAKENHI-PROJECT-23650193, KAKENHI-PROJECT-23659101, KAKENHI-PROJECT-23700416, KAKENHI-PROJECT-24240055, KAKENHI-PROJECT-24591275
[Journal Article] Comparisons of acoustic function in SCA31 and other forms of ataxias2011
- Author(s)
  Ikeda Y, Nagai M, Kurata T, Yamashita T, Ohta Y, Nagotani S, Deguchi K, Takehisa Y, Shiro Y, Matsuura T, Abe K
- Journal Title
  
  Neurol Res
  
  Volume: 33(4) Pages: 427-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice2011
- Author(s)
  Kurata T, Miyazaki K, Kozuki M, Violeta-Lukic-Panin, Morimoto N, Ohta Y, Nagai M, Ikeda Y, Matsuura T, Abe K
- Journal Title
  
  Brain Res
  
  Volume: 31 Pages: 161-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice2011
- Author(s)
  Kurata T, Miyazaki K, Kozuki M, Panin VL, Morimoto N, Ohta Y, Nagai M, Ikeda Y, Matsuura T, Abe K
- Journal Title
  
  Brain Res
  
  Volume: 1371 Pages: 161-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Disruption of neurovascular unit prior to motor neuron degeneration in amyotrophie lateral sclerosis2011
- Author(s)
  Miyazaki K, Ohta Y, Nagai M, Morimoto N, Kurata T, Takehisa Y, Ikeda Y, Matsuura T, Abe K
- Journal Title
  
  J Neurosci Res
  
  Volume: 89(5) Issue: 5 Pages: 718-28
- DOI
  10.1002/jnr.22594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Disruption of neurovascular unit prior to motor neuron degeneration in amyotrophic lateral sclerosis2011
- Author(s)
  Miyazaki K, Ohta Y, Nagai M, Morimoto N, Kurata T, Takehisa Y, Ikeda Y, Matsuura T, Abe K
- Journal Title
  
  J Neurosci Res
  
  Volume: 89(5) Pages: 718-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Parkin-Mediated Protection of Dopaminergic Neurons in a Chronic MPTP-Minipump Mouse Model of Parkinson Disease2011
- Author(s)
  Yasuda T, Hayakawa H, Nihira T, Ren YR, Nakata Y, Nagai M, Hattori N, Miyake K, Takada M, Shimada T, Mizuno Y, Mochizuki H
- Journal Title
  
  J Neuropathol Exp Neurol
  
  Volume: 70(8) Pages: 686-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Induction of parkinsonism-related proteins in the spinal motor neurons of transgenic mouse carrying a mutant SOD1 gene2010
- Author(s)
  Morimoto N, Nagai M, Miyazaki K, Ohta Y, Kurata T, Takehisa Y, Ikeda Y, Matsuura T, Asanuma M, Abe K
- Journal Title
  
  J Neurosci Res
  
  Volume: 88(8) Pages: 1804-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Induction of parkinsonism-related proteins in the spinal motor neurons of transgenic mouse carrying a mutant SOD1 gene.2010
- Author(s)
  Morimoto N, Nagai M, Miyazaki K, Ohta Y, Kurata T, Takehisa Y, Ikeda Y, Matsuura T, Asanuma M, Abe K.
- Journal Title
  
  J Neurosci Res
  
  Volume: 88(8) Pages: 1804-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Spinal anterior horn has the capacity to self-regenerate in amyotrophic lateral sclerosis model mice2009
- Author(s)
  Miyazaki K, Nagai M, Morimoto N, Kurata T, Takehisa Y, Ikeda Y, Abe K
- Journal Title
  
  J Neurosci Res
  
  Volume: 87(16) Pages: 3639-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Progressive decrease in the level of YAPdeltaCs, prosurvival isoforms of YAP, in the spinal cord of transgenic mouse carrying a mutant SOD1 gene.2009
- Author(s)
  Morimoto N, Nagai M, Mlyazaki K, Kurata T, Takehisa Y, Ikeda Y, Kamiya T Okazawa H Abe K
- Journal Title
  
  J Neurosci Res. 87
  
  Pages: 928-936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article] Changes of Nogo-A and receptor NgR in the lumbar spinal cord of ALS model mice2009
- Author(s)
  Miyazaki K, Nagai M, Ohta Y, Morimoto N, Kurata T, Murakami T, Takehisa Y, Ikeda Y, Kamiya T, Abe K
- Journal Title
  
  Neurol Res
  
  Volume: 31(3) Pages: 316-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Progressive decrease in the level of YAPdeltaCs, prosurvival isoforms of YAP, in the spinal cord of transgenic mouse carrying a mutant SODI gene.2009
- Author(s)
  Morimoto N, Nagai M, Miyazaki K, Kurata T, Takehisa Y, Ikeda Y, Kamiya T, Okazawa H, Abe K
- Journal Title
  
  J Neurosci Res. 87(4)
  
  Pages: 928-936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Spinal anterior horn has the capacity to self-regenerate in amyotrophic lateral sclerosis model mice.2009
- Author(s)
  Miyazaki K, Nagai M, Morimoto N, Kurata T, Takehisa Y, Ikeda Y, Abe K
- Journal Title
  
  J Neurosci Res. 87(16)
  
  Pages: 3639-3648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease2009
- Author(s)
  Hoang T, Choi DK, Nagai M, Wu DC, Nagata T, Prou D, Wilson GL, Vila M, Jackson-Lewis V, Dawson VL, Dawson TM, Chesselet MF, Przedborski S
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 47(7) Pages: 1049-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Progressive decrease in the level of YAPdeltaCs, prosurvival isoforms of YAP, in the spinal cord of transgenic mouse carrying a mutant SOD1 gene2009
- Author(s)
  Morimoto N, Nagai M, Miyazaki K, Kurata T, Takehisa Y, Ikeda Y, Kamiya T, Okazawa H, Abe K
- Journal Title
  
  J Neurosci Res
  
  Volume: 87(4) Pages: 928-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Mitochondrial alterations in transgenic mice with an H46R mutant Cu/Zn superoxide dismutase gene2009
- Author(s)
  Sasaki S, Aoki M, Nagai M, Kobayashi M, Itoyama Y
- Journal Title
  
  J Neuropathol Exp Neurol
  
  Volume: 68(4) Pages: 365-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Mitochondrial alterations in transgenic mice with an H46R mutant Cu/Zn superoxide dismutase gene.2009
- Author(s)
  asaki S, Aoki M, Nagai M, Kobayashi M, Itoyama Y
- Journal Title
  
  J Neuropathol Exp Neurol. 68(4)
  
  Pages: 365-373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Progressive decrease in the level of YAPdeltaCs, prosurvival isoforms of YAP, in the spinal cord of transgenic mouse carrying a mutant SOD1 gene2009
- Author(s)
  Morimoto N, Nagai M, Miyazaki K, Kurata T, Takehisa Y, Ikeda Y, Kamiya T, Okazawa H, Abe K.
- Journal Title
  
  J Neurosci Res 87
  
  Pages: 928-936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article] Early detachment of neuromuscular junction proteins in ALS mice with SODG93A mutation2009
- Author(s)
  Narai H, Manabe Y, Nagai M, Nagano I, Ohta Y, Murakami T, Takehisa Y, Kamiya T, Abe K
- Journal Title
  
  Neurol Int
  
  Volume: 1(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591083
[Journal Article] Therapeutic benefits of intrathecal protein therapy in a mouse model of amyotrophic lateral sclerosis2008
- Author(s)
  Ohta Y, Kamiya T, Nagai M, Nagata T, Morimoto N, Miyazaki K, Murakami T, Kurata T, Takehisa Y, Ikeda Y, Asoh S, Ohta S, Abe K.
- Journal Title
  
  J Neurosci Res 86
  
  Pages: 3028-3037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article]2008
- Author(s)
  Kurata T, Hayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai M, Kawarabayashi T, Takao Y, Ohta T, Harigaya Y, Manabe Y, Kamiya T, Shoji M, Abe K.
- Journal Title
  
  Neurol Res 30
  
  Pages: 860-867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article] Therapeutic benefits of intrathecal protein therapy in a mouse model of amyotrophic lateral sclerosis2008
- Author(s)
  Ohta Y, Kamiya T, Nagai M, Abe K(他8名)
- Journal Title
  
  J Neurosci Res 86(13)
  
  Pages: 3028-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590991
[Journal Article] Differentiation of PA from early PSP with different patterns of symptoms and CBF reduction.2008
- Author(s)
  Kurata T, Hayashi T, Muiakami T. Miyazaki K, Morimoto N, Ohia Y, Takthisa Y, Nagai M, Kawarabayashi T, Takao Y, Ohta T, Karigaya Y, Manabe Y, Kamiya T. shoji M, Abe K.
- Journal Title
  
  Neurol Res 30(8)
  
  Pages: 860-867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590991
[Journal Article] 遺伝性ALS2008
- Author(s)
  永井真貴子
- Journal Title
  
  モダンフィジシャン 28
  
  Pages: 1803-1807
- Data Source
  KAKENHI-PROJECT-19590991
[Journal Article] Differentiation of PA from early PSP with different patterns of symptomsand CBF reduction.2008
- Author(s)
  Kurata T, Hayashi T. Murakaoi T, Miyazaki K, Morinoto N, Ohta Y. Takehisa Y, Nagai M, Kanarabayashi T, Takao Y. Ohta. T, Harigaya Y. Manabe Y, Kamiya T. Shoji M, Abe K.
- Journal Title
  
  Neurol Res. 30
  
  Pages: 860-867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article] Therapeutic benefits of intrathecal protein therapy in a mouse model of amyotrophic lateral sclerosis.2008
- Author(s)
  Ohta Y, Kamiya T, Nagai K. Nagata T, Norimoto N, Miyazaki K. Murakami T, Kurata T. Takehisa Y, Iksda Y, Asoh s. Ohta S, Abe K.
- Journal Title
  
  J Neurosci Res. 86
  
  Pages: 3028-3037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article] PINK1, a gene product of PARK6, accumulates in □-synucleinopathy brains.2007
- Author(s)
  Murakami T, Moriwaki Y, Kawarabayashi T, Nagai M, Ohta Y, Deguchi K, Kurata T, Takehisa Y, Matsubara E, Ikeda M, Harigaya Y, Shoji M, Takahashi R, Abe
- Journal Title
  
  J Neurol Neurosurg Psychiatry. 8 (Epub ahead of prin)
- Data Source
  KAKENHI-PROJECT-17590879
[Journal Article] Early decrease of mitochondrial DNA repair enzymes in spinal motor neurons of presymptomatic transgenic mice carrying a mutant SOD1 gene.2007
- Author(s)
  Murakami T, Nagai M, Miyazaki K, Morimoto N, Ohta Y, Kurata T, Takehisa Y, Kamiya T, Ahe K
- Journal Title
  
  Brain Res 1150
  
  Pages: 182-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article] Two cases of spinocerebellar ataxia accompanied by involvement of the skeletal motor neuron system and bulbar palsy.2007
- Author(s)
  Ohta Y, Hayashi T, Nagai M, Okamoto M, Nagotani S, Nagano I, Ohmori N, Takehisa Y, Murakami T, Shoji M, Kamiya T, and Abe K
- Journal Title
  
  Intern Med 46
  
  Pages: 751-755
- NAID
  130000076727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article] Enhanced accumulation ophosphorylated alpha-synuclein in double transgenic mice expressing mutant beta-amyloid precursor protein and presenilin-12007
- Author(s)
  Kurata T, Kawarabayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai M, Ikeda M, Matsubara E, Westaway D, Hyslop PS, Harigaya Y, Kamiya T, Shoji M, Abe K.
- Journal Title
  
  J Neurosci Res 85
  
  Pages: 2246-2252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article] Early decrease of mitochondrial DNA repair enzymes in spinal motor neurons of presymptomatic transgenic mice carrying a mutant SOD1 gene.2007
- Author(s)
  Murakami T, Nagai M, Miyazaki K, Morimoto N, Ohta Y, Kurata T, Takehisa Y, Kamiya T, Abe K.
- Journal Title
  
  Brain Res. 8 (Epub ahead of prin)
- Data Source
  KAKENHI-PROJECT-17590879
[Journal Article] PINK1, a gene product of PARK6, accumulates in □-synucleinopathy brains.2007
- Author(s)
  Murakami T, Moriwaki Y, Kawarabayashi T, Nagai M, Ohta Y, Deguchi K, Kurata T, Takehisa Y, Matsubara E, Ikeda M, Harigaya Y, Shoji M, Takahashi R, Abe
- Journal Title
  
  J Neurol Neurosurg Psychiatry. 8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590879
[Journal Article] Intrathecal delivery of hepatocyte growth factor from amyotrophic lateral sclerosis onset suppresses disease progression in rat amyotrophic lateral sclerosis model2007
- Author(s)
  Ishigaki A, Aoki M, Nagai M, Itoyama Y(他5名)
- Journal Title
  
  J Neuropathol Exp Neurol 66(11)
  
  Pages: 1037-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590991
[Journal Article] Early decrease of mitochondrial DNA repair enzymes in spinal motor neurons of presymptomatic transgenic mice carrying a mutant SOD1 gene.2007
- Author(s)
  Murakami T, Nagai M, Miyazaki K, Morimoto N, Ohta Y, Kurata T, Takehisa Y, Kamiya T, Abe K
- Journal Title
  
  Brain Res. 8(Epub ahead of prin)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590879
[Journal Article] Increased autophagy in transgenic mice with a G93A mutant SOD1 gene2007
- Author(s)
  Morimoto N, Nagai M, Ohta Y, Miyazaki K, Kurata T, Morimoto M, Murakami T, Takehisa Y, Ikeda Y, Kamiya T, Abe K.
- Journal Title
  
  Brain Res 1167
  
  Pages: 112-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article] Motor Neuron Disease in Transgenic Mice With an H46R Mutant SOD1 Gene.2007
- Author(s)
  Sasaki S, Nagai M, Aoki M, Komori T, Itoyama Y, Iwata M
- Journal Title
  
  J Neuropathol Exp Neurol 66
  
  Pages: 517-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590991
[Journal Article] Two cases of spinocerebellar ataxiaccompanied by involvement of the skeletal motor neuron system and bulbar palsy2007
- Author(s)
  Ohta Y, Hayashi T, Nagai M, Okamoto M, Nagotani S, Nagano I, Ohmori N, TakehisaY, Murakami T, Shoji M, Kamiya T, and Abe K.
- Journal Title
  
  Intern Med 46
  
  Pages: 751-755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article] Early decrease of mitochondrial DNA repair enzymes in spinal motor neurons of presymptomatic transgenic mice carrying a mutant SOD1 gene.2007
- Author(s)
  Murakami T, Nagai M, Miyazaki K, Morimoto N, Ohta Y, Kurata T, Takehisa Y, Kamiya T, Abe K.
- Journal Title
  
  Brain Res. 8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590879
[Journal Article] PINK1, a gene product of PARK6, accumulates in □-synucleinopathy brains.2007
- Author(s)
  Murakami T, Moriwaki Y, Kawarabayashi T, Nagai M, Ohta, Y, Deguchi K, Kurata T, Takehisa Y, Matsubara E, Ikeda M, Harigaya Y, Shoji M, Takahashi R, Abe
- Journal Title
  
  J Neurol Neurosurg Psychiatry. 8(Epub ahead of prin)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590879
[Journal Article] Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons.2007
- Author(s)
  Nagai M, Re DB, Nagata T, Chalazonitis A, Jessell TM, Wichterle H, Przedborski S.
- Journal Title
  
  Nature Neurosci. 10(5)
  
  Pages: 615-622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590991
[Journal Article] Enhanced accumulation of phosphorylated alpha-synuclein in double transgenic mice expressing mutant beta-amyloid precursor prtotein and presenilin-1.2007
- Author(s)
  Kurata T, Kawarabayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai N, Ikeda M, Natsubara E, Westaway D, Hyslop PS, Harigaya Y, Kamiya T, Shoji M, Abe K
- Journal Title
  
  J Neurosci Res 85
  
  Pages: 2246-2252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article] Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons2007
- Author(s)
  Nagai M, Re DB, Nagata T, Chalazonitis A, Jessell TM, Wichterle H, Przedborski S
- Journal Title
  
  Nature Neurosci 10(5)
  
  Pages: 615-622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590991
[Journal Article] Increased autophagy in transgenic mice with a G93A mutant SOD1 gene2007
- Author(s)
  Morimoto N, Nagai M, Abe K(他8名)
- Journal Title
  
  Brain Res 1167
  
  Pages: 112-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590991
[Journal Article] Increased autophagy in transgenic mice with a G93A mutant SOD1 gene.2007
- Author(s)
  Morimoto N, Nagai M, Ohta Y, Miyazaki K, Kurata T, Morimoto M, Murakami T, Takehisa Y, Ikeda Y, Kamiya T, Ahe K.
- Journal Title
  
  Brain Res. 1167
  
  Pages: 112-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590991
[Journal Article] Motor Neuron Disease in Transgenic Mice With an H46R Mutant SOD1 Gene2007
- Author(s)
  Sasaki S, Nagai M, Iwata M(他3名)
- Journal Title
  
  J Neuropathol Exp Neurol 66
  
  Pages: 517-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590991
[Journal Article] Increased autophagy in transgenic mice with a G93A mutant SOD1 gene.2007
- Author(s)
  Morimoto N, Nagai M, Ohta Y, Miyazaki K, Kurata T, Morimoto M, Murakami T, Takehisa Y, Ikeda Y, Kamiya T, Abe K
- Journal Title
  
  Brain Res 1167
  
  Pages: 112-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article] Early decrease of mitochondrial DNA repair enzymes in spinal motor neurons of presymptomatic transgenic mice carrying a mutant SOD1 gene2007
- Author(s)
  Murakami T, Nagai M, Miyazaki K, Morimoto N, Ohta Y, Kurata T, Takehisa Y, Kamiya T, Abe K.
- Journal Title
  
  Brain Res 1150
  
  Pages: 182-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article] Intrathecal injection of epidermal growth factor and fibroblast growth factor 2 promotes proliferation of neural precursor cells in the spinal cords of mice with mutant human SOD1 gene2006
- Author(s)
  Ohta Y, Nagai M, Nagata T, Murakami T, Nagano I, Narai H, Kurata T, Shiote M, Shoji M, Abe K.
- Journal Title
  
  J Neurosci Res 84
  
  Pages: 980-992
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article] Intrathecal injection of epidermal growth factor and fibroblast growth factor 2 promotes proliferation of neural precursor cells in the spinal cords of mice with mutant human SOD1 gene.2006
- Author(s)
  Ohta Y, Nagai M, Nagata T, Murakami T, Nagano I, Narai H, Kurata T, Shiote M, Shoji M, Abe K.
- Journal Title
  
  J. Neurosci. Res. 84
  
  Pages: 980-992
- Data Source
  KAKENHI-PROJECT-17590879
[Journal Article] Intrathecal injection of epidermal growth factor and fibroblast growth factor 2 promotes proliferation of neural precursor cells in the spinal cords of mice with mutant human SOD1 gene.2006
- Author(s)
  Ohta Y, Nagai M, Nagata T, Murakami T, Nagano I, Narai H, Kurata T, Shiote M, Shoji M, Abe K
- Journal Title
  
  J Neurosci Res. 84
  
  Pages: 980-992
- Data Source
  KAKENHI-PROJECT-18390257
[Journal Article] Intrathecal injection of epidermal growth factor and fibroblast growth factor 2 promotes proliferation of neural precursor cells in the spinal cords of mice with mutant human SOD1 gene.2006
- Author(s)
  Ohta Y, Nagai M, Nagata T, Murakami T, Nagano I, Narai H, Kurata T, Shiote M, Shoji M, Abe K
- Journal Title
  
  J. Neurosci. Res. 84
  
  Pages: 980-992
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590879
[Journal Article] Intrathecal injection of epidermal growth factor and fibroblast growth factor 2 promotes proliferation of neural precursor cells in the spinal cords of mice with mutant human SOD1 gene
- Author(s)
  Ohta Y, Nagai M, Nagata T, Murakami T, Nagano I, Narai H, Kurata T, Shiote M, Shoji M, Abe K.
- Journal Title
  
  J. Neurosci. Res. 8 4
  
  Pages: 980-992
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590879
[Presentation] 認知症を伴う筋萎縮性側索硬化症の臨床・病理学的評価2015
- Author(s)
  永井真貴子，川浪文，近藤裕子，西山和利
- Organizer
  第34回日本認知症学会学術集会
- Place of Presentation
  リンクステーションホテル（青森市）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-24591275
[Presentation] 認知症を伴った筋萎縮性側索硬化症剖検脳の免疫組織学的検討2015
- Author(s)
  永井真貴子，川浪文、荻野美恵子、西山和利
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟市）
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-24591275
[Presentation] TDP43発現ALSマウスモデルの作製2012
- Author(s)
  永井真貴子，川浪文，早川英規，仁平友子，望月秀樹
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591275
[Presentation] Mutant TDP-43 overexpression produces the motor neuron cell death in mouse spinal cord.2012
- Author(s)
  Nagai M, Kawanami A, NihiraT, Hayakawa H, Nakata Y, Mizuno Y, Mochizuki H
- Organizer
  8th FENS Forum of Neuroscience
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-24591275
[Presentation] ALS患者における黒質神経細胞脱落の検討2011
- Author(s)
  遠藤基, 早川英規, 梁正淵, 永井真貴子, 荻野美恵子, 望月秀樹
- Organizer
  第52回日本神経学会学術大会
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-21591083
[Presentation] ALS剖検脊髄の免疫染色による検討2011
- Author(s)
  永井真貴子, 早川英規, 荻野美恵子, 望月秀樹
- Organizer
  第52回日本神経学会学術大会
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-21591083
[Presentation] ALS剖検脊髄の免疫染色による検討2011
- Author(s)
  永井真貴子, 早川英規, 荻野美恵子, 望月秀樹
- Organizer
  日本神経学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-21591083
[Presentation] ALS患者における栄養管理と生命予後2009
- Author(s)
  永井真貴子、出口健太郎、名古谷章子、池田佳生、阿部康二
- Organizer
  第27回日本神経治療学会総会
- Year and Date
  2009-06-11
- Data Source
  KAKENHI-PROJECT-21591083
[Presentation] 運動ニューロンを障害する変異SOD1アストロサイト由来液性因子の解析2009
- Author(s)
  永田哲也, Diane Re, 永井真貴子, Serge Przedborski, 阿部康二
- Organizer
  第50回日本神経学会学術大会
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-21591083
[Presentation] 変異SOD1遺伝子発現アストロサイトの運動神経細胞死への関与2008
- Author(s)
  永井真貴子
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-19590991
[Presentation] Increased autophagy in transgenic mice with a G93A mutant SOD1 gene2008
- Author(s)
  Morimoto N, Nagai M, Miyazaki K, KurataT, Takehisa Y, Ikeda Y, Kamiya T, Abe K.
- Organizer
  12th Congress of the European Federation of Neurologica Societies
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-18390257
[Presentation] Increased autophagy in transgenic mice with a G93A mutant SOD1 gene.2008
- Author(s)
  Morimoto N, Nagai M, Miyazaki K, Kurata T, Takehisa Y, Ikeda Y, Kamiya T, Abe K.
- Organizer
  12th Congress of the European Federation of Neurological Societies
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-18390257
[Presentation] 変異SOD1遺伝子発現アストロサイトの運動神経細胞死への関与2008
- Author(s)
  永井真貴子, 宮崎一徳, 森本展年, 倉田智子, 武久康, 池田佳生, 神谷達司, 阿部康二
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590991
[Presentation] Enhanced accumulation of phosphorylated α-synuclein in transgenic mice expressing APP and PS-1.2007
- Author(s)
  Kurata T, Kawarabayashi T, Nurakami T, Morimoto N, Ota Y, Ikeda Y, Nagai N, Takehisa Y, Matsubara E, David Westaway, Peter St. George Hyslop, Harigaya Y, Kamiya T, Shoji M, and Abe K
- Organizer
  13th Congress of International Psychogeriatric Association
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-18390257
[Presentation] Dysfunction of mitochondrial oxidative phosphorylation in ALS rat model2007
- Author(s)
  Nagai M
- Organizer
  The 23^<rd> International symposium on Cerebral Blood Flow and Metabolism
- Place of Presentation
  大阪
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-19590991
[Presentation] Dysfunction ofmitochondrial oxidative phosphorylation in ALS rat model2007
- Author(s)
  Nagai M, Murakami T, Ohta Y, Takehisa Y, Morimoto N, Miyazaki K, Kurata T, Kamiya T, Abe K, and Przedborski S.
- Organizer
  The 23rd InternatSymposium on Cerebral Blood Flow, Metabolism and The 8th International Conference on Quantification of Brain Functio with PET
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-18390257
[Presentation] Beneficial Effects of Intrathecal Administration in Patients with Amyotrophic Lateral Screlosis.2007
- Author(s)
  Morimoto N, Nagano I, Murakami T, Nagai M, Shiote M, Ohta Y, Morimoto M, Takehisa Y, Kamiya T, and Abe K
- Organizer
  The 23rd International Symposium on Cerebral Blood Flow, Metabolism and The 8th International Conference on Quantification of Brain Function with PET
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-18390257
[Presentation] Enhanced accumulation of phosphorylated α-synuclein in transgenic mice eAPP and PS-12007
- Author(s)
  Kurata T, Kawarabayashi T, Murakami T, Morimoto N, Ota Y, Ikeda Y, Nagai M, Takehisa Y, Matsubara E, David Westaway, Peter St. George Hyslop, Harigaya Y, T, Shoji M, and Abe K.
- Organizer
  13th Congress of International Psychogeriatric
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-18390257
[Presentation] Beneficial Effectsof Intrathecal Administration in Patientswith Amyotrophic Lateral Screlosis2007
- Author(s)
  Morimoto N, Nagano I, Murakami T, Nagai M, Shiote M, Ohta Y, Morimoto M, Takehisa Y, Kamiya T, and Abe K.
- Organizer
  The 23rd International Symposium on CereBlood Flow, Metabolism and ThInternational Conference on Quantification of Brain Funct
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-18390257
[Presentation] Intrathecal injection of EGF and FGF2 promotes proliferation of neural precursor cells in the spinal cords owith mutant human SOD1 gene2007
- Author(s)
  Ohta Y, Nagai M, Nagata T, Murakami T, Nagano I, Narai H, Kurata T, Shiote M, Shoji M, and Abe K.
- Organizer
  12thInternational Congress of World Muscle Society
- Place of Presentation
  Naxos, Italy
- Data Source
  KAKENHI-PROJECT-18390257
[Presentation] Familial ALS with a novel Leu126Ser mutation in the SOD1 gene showing mild clinical features and low penetrance in females2007
- Author(s)
  Takehisa Y, Murakami T, Nagai M, Ohta Y, Morimoto N, Ikeda Y, Kamiya T, and Abe K.
- Organizer
  The 23rd International Symposium on Cerebral Blood Flow, Metabolism8th International Conference on Quantification of Brain Function with PET
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-18390257
[Presentation] Familial ALS with a novel Leu126Ser mutation in the SOD1 gene showing mild clinical features and low penetrance in females.2007
- Author(s)
  Takehisa Y, Murakami T, Nagai M, Ohta Y, Morimoto N, Ikeda Y, Kamiya T, and Abe K
- Organizer
  The 23rd International Symposium on Cerebral Blood Flow, Metabolism and The 8th International Conference on Quantification of Brain Function with PET
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-18390257
[Presentation] Dysfunction of mitochondrial oxidative phosphorylation in ALS rat model.2007
- Author(s)
  Nagai M, Ohta Y, Morimoto N, Miyazaki K, Kurata T, Morimoto M, Murakami T, Takehisa Y, Ikeda Y, Kamiya T, Abe K.
- Organizer
  Brain 07
- Place of Presentation
  Osaka
- Year and Date
  2007-05-21
- Data Source
  KAKENHI-PROJECT-19590991
[Presentation] Intrathecal injection of EGF and FGF2 promotes proliferation of neural precursor cells in the spinal cords of mice with mutant human SOD1 gene.2007
- Author(s)
  Ohta Y, Nagai M, Nagata T, Murakami T, Nagano I, Narai H, Kurata T, Shiote M, Shoji M, and Abe K
- Organizer
  12th International Congress of World Muscle Society
- Place of Presentation
  Naxos, Italy
- Data Source
  KAKENHI-PROJECT-18390257
[Presentation] Dysfunction of mitochondrial oxidative phosphorylation in ALS rat model.2007
- Author(s)
  Nagai M, Murakami T, Ohta Y, Takehisa Y, Morimoto N, Miyazaki K, Kurata T, Kamiya T, Abe K, and Przedborski S
- Organizer
  The 23rd International Symposium on Cerebral Blood Flow, Metabolism and The 8th International Conference on Quantification of Brain Function with PET
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-18390257
[Presentation] Enhanced accumulation of phosphorylated α-synuclein in transgenic mice expressingAPP and PS-12006
- Author(s)
  Kurata T, Kawarabayashi T, Murakami T, Miyazaki K, Morimoto N, Ota Y, Takehisa Y, Nagai M, Ikeda M, Matsubara E, Westaway D, St George Hyslop P, Harigaya Y, Kamiya T, Shoji M, and Abe K.
- Organizer
  The 6^<th> Annual Meetingof International Collegeof Geriatric Psychoneuropharmacology
- Place of Presentation
  Hiroshima, Japan
- Data Source
  KAKENHI-PROJECT-18390257
[Presentation] Accumulation of Parkinson's-disease-related moleculLewy bodies and glial cytoplasmic inclusions2006
- Author(s)
  Murakami T, Imai Y, Inoue H, Kawarabayashi T, Nagai M, Kurata T, Takehisa Y, Harig Y, Shoji M, Takahashi Y, Harigaya Y, Shoji M, Takahashi R, and Abe K.
- Organizer
  10^<th> International Congress of Parkinson's Disease and Movement
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-18390257
[Presentation] Beneficial effects of intrathecal IGF-1 administration inpatients with amyotrophic lateralsclerosis2006
- Author(s)
  Murakami T, Nagano I, Nagai M, Shiote M, Ohta Y, Morimoto N, Takehisa Y, Kaand Abe K.
- Organizer
  17^<th> International Symposium on ALS/MND
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-18390257
[Presentation] TDP-43のC末端断片発現ALSモデルマウスの作製
- Author(s)
  永井真貴子，川浪文、仁平友子、西山和利
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡国際会議場（福岡県・福岡市）
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24591275
[Presentation] C-terminal fragment of TDP-43 induce chronic motor neuron degeneration in mouse spinal cord
- Author(s)
  Nagai M, Kawanami A, Nihira T, Nishiyama K, Mizuno Y.
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24591275
[Presentation] C-terminal fragment of TDP-43 induce chronic motor neuron degeneration in mouse spinal cord
- Author(s)
  Nagai M, Kawanami A, Nihira T, Nishiyama K.
- Organizer
  9th FENS Forum of Neuroscience
- Place of Presentation
  ミラノ（イタリア）
- Year and Date
  2014-07-05 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-24591275
[Presentation] TDP-43のC末端断片発現ALSモデルマウスの作成
- Author(s)
  永井真貴子，川浪文，仁平友子，早川英規，水野美邦，西山和利
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591275
[Presentation] 孤発性ALS剖検脊髄におけるOptineurin陽性封入体の検討
- Author(s)
  川浪文，永井真貴子，仁平友子，荻野美恵子，西山和利
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡国際会議場（福岡県・福岡市）
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24591275

1. ABE Koji (20212540)

# of Collaborated Projects: 3 results

# of Collaborated Products: 39 results
2. TAKEHISA Yasushi (00379752)

# of Collaborated Projects: 2 results

# of Collaborated Products: 33 results
3. MURAKAMI Tetsuro (70403475)

# of Collaborated Projects: 2 results

# of Collaborated Products: 34 results
4. HAYASHI Takeshi (40314679)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KAMIYA Tatsushi (70233955)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results
6. IKEDA Yoshio (00282400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
7. SHOJI Mikio (60171021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 永野功 (80335603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 永田哲也 (50362976)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 瓦林毅 (90186156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. 前川達則 (30647673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 太田悦朗 (60508042)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NIHIRA Tomoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
14. KAWANAMI Aya

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
15. 阪上洋行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagai Makiko 永井 真貴子

永井 真貴子 ナガイ マキコ

NAGAI Makiko 永井 真貴子

Research Projects

Research Products

Co-Researchers

腸管神経におけるalphaシヌクレインの凝集と水膜輸送の関係

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Analysis for prion-like propagation of pathological TDP-43Principal Investigator

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The production of newly ALS model micePrincipal Investigator

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Analysis for factors toxic to motor neurons released from astrocytes expressing ALS-linked mutated SOD1.Principal Investigator

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Analysis of the mutated SOD1 astrocyte-releasing factors toxic to motor neuronsPrincipal Investigator

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Molecular characterization and gene/regeneration therapy for amyotrophic lateral sclerosis

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Anti-apoptotic Therapy (Intrathecal Injection of Anti-apoptotic PTD-FNK Protein) in a Mouse Model of Amyotrophic Lateral Sclerosis

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The study for the molecular mechanisms and the newly developed treatment for ALS

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[Book] パーキンソン病の細胞移植・遺伝子治療2010

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[Journal Article] Clinicopathological examination of optineurin-immunoreactive inclusions in patients with sporadic ALS2015

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NAID

Data Source

[Journal Article] Loss of DARPP-32 and calbindin in multiple system atrophy2013

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DOI

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[Journal Article] 筋萎縮性側索硬化症の病態解明と治療戦略2012

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Journal Title

NAID

Data Source

[Journal Article] Accumulation of a-synuclein triggered by presynaptic dysfunction2012

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Journal Title

DOI

Data Source

[Journal Article] Comparisons of acoustic function in SCA31 and other forms of ataxias2011

Author(s)

Nagai Makiko 永井真貴子

永井真貴子ナガイマキコ

NAGAI Makiko 永井真貴子