MAEHARA Kayoko 前原佳代子

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Maehara Kayoko 前原佳代子

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Researcher Number	80421311
Other IDs	https://orcid.org/0000-0001-5573-7673
Affiliation (Current)	2025: 畿央大学, 健康科学部, 教授
Affiliation (based on the past Project Information) *help	2015 – 2018: 畿央大学, 健康科学部, 教授 2012 – 2014: 独立行政法人国立成育医療研究センター, 周産期病態研究部, 室長 2010: Kurume University, 周産期病態研究部, 室長 2008 – 2009: Kurume University, 分子生命科学研究所, 助教
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Experimental pathology
Keywords	Principal Investigator 産科学 / 細胞・組織 / 遺伝子 / ゲノム編集 / NLRP7遺伝子 / 反復胞状奇胎 / ゲノム / 一塩基多型 / 周産期疾患 / 細胞 … More / ヘテロクロマチン / CENP-B / CENP-A / セントロメア / 染色体 / 細胞老化 Less

The analysis of roles of NLRP7 in molar pregnancies using NLRP7-deleted HTR-8/SVneo cells.Principal Investigator
- Principal Investigator
  
  Maehara Kayoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kio University
The analysis of genetic features of rare obstetric diseases using whole-exome sequencing and genome-wide association studyPrincipal Investigator
- Principal Investigator
  
  Maehara Kayoko
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kio University
  National Research Institute for Child Health and Development
Do centromere proteins play a crucial role in regulating commitment to the senescent state?Principal Investigator
- Principal Investigator
  
  MAEHARA Kayoko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kurume University

All 2018 2017 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] 学生と考える生命倫理［第2版］2018
- Author(s)
  金子　章道、金内　雅夫、河野　由美、島　恒生、前原　佳代子、堀江　尚子、藤澤　弘枝、福本　貴彦、山本　隆、森岡　周、西井　康惠、訓覇　秋麿、細越　寛樹、小野　尚香、安井　義和
- Total Pages
  232
- Publisher
  ナカニシヤ出版
- ISBN
  9784779512216
- Data Source
  KAKENHI-PROJECT-16K11120
[Book] Senescence2012
- Author(s)
  Maehara K
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-24592494
[Journal Article] Elucidation of the developmental mechanism of ovarian mature cystic teratomas using B allele-frequency plots of single nucleotide polymorphism array data2018
- Author(s)
  Usui Hirokazu、Nakabayashi Kazuhiko、Kaku Hiroshi、Maehara Kayoko、Hata Kenichiro、Shozu Makio
- Journal Title
  
  Genes, Chromosomes and Cancer
  
  Volume: 57 Issue: 8 Pages: 409-419
- DOI
  10.1002/gcc.1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08689, KAKENHI-PROJECT-18K09281, KAKENHI-PROJECT-17H01588, KAKENHI-PROJECT-16K11120
[Journal Article] A versatile technology for targeted genome editing has an impact on our lives.2017
- Author(s)
  前原　佳代子
- Journal Title
  
  畿央大学紀要
  
  Volume: 14 Issue: 1 Pages: 1-8
- DOI
  10.24482/00000009
- NAID
  120006323665
- URL
  https://kio.repo.nii.ac.jp/records/18
- Year and Date
  2017-06-30
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11120
[Journal Article] Genomic, epigenomic, and transcriptomic profiling towards identifying omics -features and specific biomarkers that distinguish uterine leiomyosarcoma and leiomyoma at molecular levels.2015
- Author(s)
  Miyata T, Sonoda K, Tomikawa J, Tayama C, Maehara K, Kobayashi H, Wake N, Kato K, Hata K, Nakabayashi K
- Journal Title
  
  Sarcoma
  
  Volume: 2015 Pages: 412068-412068
- DOI
  10.1155/2015/412068
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460409, KAKENHI-PROJECT-24592494
[Journal Article] Novel Nonsense Mutation in the NLRP7 Gene Associated with Recurrent Hydatidiform Mole.2015
- Author(s)
  Ito Y, Maehara K, Kaneki E, Matsuoka K, Sugahara N, Miyata T, Kamura H, Yamaguchi Y, Kono A, Nakabayashi K, Migita O, Higashimoto K, Soejima H, Okamoto A, Nakamura H, Kimura T, Wake N, Taniguchi T, Hata K.
- Journal Title
  
  Gynecol Obstet Invest
  
  Volume: Epub ahead of print Issue: 4 Pages: 1-6
- DOI
  10.1159/000441780
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860258, KAKENHI-PROJECT-24592494, KAKENHI-PROJECT-26670169, KAKENHI-PROJECT-16K11086, KAKENHI-PROJECT-16K11087, KAKENHI-PROJECT-16K11120
[Journal Article] Compilation of copy number variants identified in phenotypically normal and parous Japanese women2014
- Author(s)
  Migita O, Maehara K, Kamura H, Miyakoshi K, Tanaka M, Morokuma S, Fukushima K, Shimamoto T, Saito S, Sago H, Nishihama K, Abe K, Nakabayashi K, Umezawa A, Okamura K, Hata K
- Journal Title
  
  J. Hum. Genet.
  
  Volume: 59 Issue: 6 Pages: 326-331
- DOI
  10.1038/jhg.2014.27
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23770273, KAKENHI-PROJECT-24592494, KAKENHI-PROJECT-25860258, KAKENHI-PROJECT-26670717
[Journal Article] Cellular senescence as a self-defense mechanism against centromere dysfunction.2011
- Author(s)
  Maehara, K.
- Journal Title
  
  Biomedical Gerontology
  
  Volume: 35 Pages: 17-23
- NAID
  10027835722
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590387
[Journal Article] Cellular senescence as a self-defense mechanism against centromere dysfunction.2011
- Author(s)
  Maehara K.
- Journal Title
  
  Biomedical Gerontology Vol.35
  
  Pages: 17-23
- NAID
  10027835722
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590387
[Journal Article] CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses2010
- Author(s)
  Maehara, K., Takahashi K., Saitoh S.
- Journal Title
  
  Mol.Cell.Biol. 30
  
  Pages: 2090-2104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590387
[Journal Article] CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses.2010
- Author(s)
  Maehara K., Takahashi K., Saitoh S.
- Journal Title
  
  Mol.Cell.Biol. Vol.30
  
  Pages: 2090-2104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590387
[Journal Article] CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses.2010
- Author(s)
  Maehara, K., Takahashi K., Saitoh S.
- Journal Title
  
  Mol.Cell.Biol.
  
  Volume: 30 Pages: 2090-2104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590387
[Presentation] ヒト早老症モデル細胞の開発2018
- Author(s)
  前原佳代子
- Organizer
  第36回日本ヒト細胞学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11120
[Presentation] 日本人妊娠糖尿病の分子遺伝学的病態解析2015
- Author(s)
  春日義史、秦健一郎、宮越敬、福武麻里絵、正木繭、池ノ上学、落合大吾、松本直、峰岸一宏、前原佳代子、田中守、青木大輔
- Organizer
  第67回日本産科婦人科学会学術講演会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-04-11
- Data Source
  KAKENHI-PROJECT-24592494
[Presentation] 正常分娩妊婦に観察される遺伝的多様性2013
- Author(s)
  右田王介、前原佳代子、嶋本富博、諸隈誠一、福嶋恒太郎、和氣徳夫、左合治彦、宮越敬、田中守、齋藤滋、秦健一郎
- Organizer
  日本産科婦人科学会　第65回学術講演会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24592494
[Presentation] The alteration of centromere in cellular senescence2012
- Author(s)
  Maehara K
- Organizer
  2012 Spring Conference of the Korea Society for Gerontology and the 11th Korea-Japan Gerontologist Joint meeting
- Place of Presentation
  Osong Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24592494
[Presentation] 日本人集団に共通するコピー数多型2012
- Author(s)
  右田王介、前原佳代子、岡村浩司、西濱啓一郎、中林一彦、秦健一郎
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24592494
[Presentation] 生殖補助医療技術が出生児のDNAメチル化状態に及ぼす影響の検討2012
- Author(s)
  久須美真紀、中林一彦、前原佳代子、田嶋敦、秦健一郎
- Organizer
  第6回日本エピジェネティクス研究会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24592494
[Presentation] CENP-Aノックダウンによる細胞老化とp53の役割2010
- Author(s)
  前原佳代子
- Organizer
  第27回染色体ワークショップ
- Place of Presentation
  御殿場市
- Data Source
  KAKENHI-PROJECT-20590387
[Presentation] CENP-Aの低下は、p53依存性の細胞老化を誘導し、染色体分配異常を抑制する2010
- Author(s)
  前原佳代子
- Organizer
  第33回日本基礎老化学会
- Place of Presentation
  名古屋市
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-20590387
[Presentation] 動原体機能不全はヒト正常細胞では細胞老化を誘導する2010
- Author(s)
  前原佳代子
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20590387
[Presentation] CENP-Aの低下はp53依存性の細胞老化を誘導し染色体分配異常を抑制する2010
- Author(s)
  前原佳代子
- Organizer
  第33回日本基礎老化学会
- Place of Presentation
  名古屋大学(愛知県)
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-20590387
[Presentation] 動原体機能不全はヒト正常細胞では細胞老化を誘導する2010
- Author(s)
  前原佳代子
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20590387
[Presentation] CENP-Aの低下と細胞老化2009
- Author(s)
  前原佳代子
- Organizer
  第26回染色体ワークショップ
- Place of Presentation
  姫路市
- Data Source
  KAKENHI-PROJECT-20590387
[Presentation] CENP-Aの低下と細胞老化2009
- Author(s)
  前原佳代子
- Organizer
  第26回染色体ワークショップ
- Place of Presentation
  姫路
- Data Source
  KAKENHI-PROJECT-20590387
[Presentation] 染色体安定分配に必須な動原体タンパク質CENP-Aと細胞老化機構の機能的関連2009
- Author(s)
  前原佳代子
- Organizer
  第32回日本基礎老化学会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-20590387
[Presentation] キネトコア機能異常と細胞老化2008
- Author(s)
  前原佳代子
- Organizer
  第31回日本基礎老化学会
- Place of Presentation
  松本市
- Data Source
  KAKENHI-PROJECT-20590387
[Presentation] キネトコア機能異常と細胞老化2008
- Author(s)
  前原佳代子
- Organizer
  第31回日本基礎老化学会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-20590387
[Presentation] Copy number variants identified in Japanese women.
- Author(s)
  Migita O., Maehara K., Nakabayashi K., Okamura K., and Hata K.
- Organizer
  The American Society of Human Genetics 2014 Annual Meeting
- Place of Presentation
  U.S.A.
- Year and Date
  2014-10-18 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-24592494
[Presentation] 日本人妊娠糖尿病の分子遺伝学的病態解析
- Author(s)
  春日義史、秦健一郎、宮越敬、福武麻里絵、正木繭、池ノ上学、落合大吾、松本直、峰岸一宏、前原佳代子、田中守、青木大輔
- Organizer
  第67回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜
- Year and Date
  2015-04-10 – 2015-04-12
- Data Source
  KAKENHI-PROJECT-24592494
[Presentation] SNPアレイ解析による雄核発生ヘテロ奇胎発生機序の推定
- Author(s)
  碓井宏和、瞿佳、前原佳代子、塙真輔、山本憲子、錦見恭子、植原貴史、楯真一、三橋暁、秦健一郎、生水真紀夫
- Organizer
  第66回日本産科婦人科学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2014-04-18 – 2014-04-20
- Data Source
  KAKENHI-PROJECT-24592494
[Presentation] 日本人正常分娩妊婦集団の遺伝的特徴～標準データとしての有用性と注意点～
- Author(s)
  右田王介、前原佳代子、嶋本富博、諸隈誠一、福嶋恒太郎、和氣徳夫、宮越敬、田中守、齋藤滋、左合治彦、秦健一郎
- Organizer
  第66回日本産科婦人科学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2014-04-18 – 2014-04-20
- Data Source
  KAKENHI-PROJECT-24592494
[Presentation] ヒト新規中心体タンパクMOREの機能解析
- Author(s)
  伊藤睦美，荻山友貴，榊みずほ，石井浩二郎，齋藤成昭，秦健一郎，高橋考太，前原佳代子
- Organizer
  第31回染色体ワークショップ・第12回核ダイナミクス研究会
- Place of Presentation
  足柄下郡
- Data Source
  KAKENHI-PROJECT-24592494
[Presentation] ヒト新規中心体タンパクMOREの機能解析
- Author(s)
  伊藤睦美，荻山友貴，榊みずほ，石井浩二郎，齋藤成昭，秦健一郎，高橋考太，前原佳代子
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24592494
[Presentation] 日本人正常分娩集団に観察される遺伝的多様性
- Author(s)
  右田王介，岡村浩司，前原佳代子，嘉村浩美，中林一彦，秦健一郎
- Organizer
  日本人類遺伝学会第58回大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24592494
[Presentation] 正常分娩妊婦に観察される遺伝的多様性
- Author(s)
  右田王介, 前原佳代子, 嶋本富博, 諸隈誠一, 福嶋恒太郎, 和氣徳夫, 左合治彦, 宮越敬, 田中守, 齋藤滋, 秦健一郎
- Organizer
  日本産婦人科学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24592494
[Presentation] 正常二倍体だが反復する胞状奇胎に観察される母由来アレルのDNAメチル化異常とNLRP7遺伝子変異
- Author(s)
  伊藤由紀、前原佳代子、兼城英輔、宮田知子、増田彩子、右田王介、岡村愛光、中村仁美、木村正、和氣徳夫、谷口武、秦健一郎
- Organizer
  第66回日本産科婦人科学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2014-04-18 – 2014-04-20
- Data Source
  KAKENHI-PROJECT-24592494
[Presentation] ヒト老化細胞を利用したエピゲノム解析
- Author(s)
  榊みずほ、海老原侑子、岡村浩司、中林一彦、秦健一郎、小林芳郎、前原佳代子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24592494

1. 祐實泰子 (80425454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KAMURA Hiromi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. TAYAMA Chiharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. MIGITA Ohsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 中林一彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 冨川順子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 岡村浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MAEHARA Kayoko 前原 佳代子

Maehara Kayoko 前原 佳代子

Research Projects

Research Products

Co-Researchers

The analysis of roles of NLRP7 in molar pregnancies using NLRP7-deleted HTR-8/SVneo cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analysis of genetic features of rare obstetric diseases using whole-exome sequencing and genome-wide association studyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Do centromere proteins play a crucial role in regulating commitment to the senescent state?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 学生と考える生命倫理［第2版］2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] Senescence2012

Author(s)

Publisher

Data Source

[Journal Article] Elucidation of the developmental mechanism of ovarian mature cystic teratomas using B allele-frequency plots of single nucleotide polymorphism array data2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A versatile technology for targeted genome editing has an impact on our lives.2017

Author(s)

Journal Title

DOI

NAID

URL

Year and Date

Language

Data Source

[Journal Article] Genomic, epigenomic, and transcriptomic profiling towards identifying omics -features and specific biomarkers that distinguish uterine leiomyosarcoma and leiomyoma at molecular levels.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel Nonsense Mutation in the NLRP7 Gene Associated with Recurrent Hydatidiform Mole.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Compilation of copy number variants identified in phenotypically normal and parous Japanese women2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cellular senescence as a self-defense mechanism against centromere dysfunction.2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Cellular senescence as a self-defense mechanism against centromere dysfunction.2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses2010

Author(s)

Journal Title

Data Source

[Journal Article] CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses.2010

Author(s)

Journal Title

Data Source

MAEHARA Kayoko 前原佳代子

Maehara Kayoko 前原佳代子